-
3
-
-
0036963754
-
Characterization of the thyrotropin binding pocket
-
Jeffreys J, Depraetere H, Sanders J, Oda Y, Evans M, Kiddie A, Richards, T, Furmaniak J, Rees Smith B 2002 Characterization of the thyrotropin binding pocket. Thyroid 12:1051-1061.
-
(2002)
Thyroid
, vol.12
, pp. 1051-1061
-
-
Jeffreys, J.1
Depraetere, H.2
Sanders, J.3
Oda, Y.4
Evans, M.5
Kiddie, A.6
Richards, T.7
Furmaniak, J.8
Rees Smith, B.9
-
4
-
-
12244265471
-
Thyroid-stimulating monoclonal antibodies
-
Sanders J, Jeffreys J, Depraetere H, Richards T, Evans M, Kiddie A, Brereton K, Groenen M, Oda Y, Furmaniak J, Rees Smith B 2002 Thyroid-stimulating monoclonal antibodies. Thyroid 12:1043-1050.
-
(2002)
Thyroid
, vol.12
, pp. 1043-1050
-
-
Sanders, J.1
Jeffreys, J.2
Depraetere, H.3
Richards, T.4
Evans, M.5
Kiddie, A.6
Brereton, K.7
Groenen, M.8
Oda, Y.9
Furmaniak, J.10
Rees Smith, B.11
-
5
-
-
0037967531
-
Human monoclonal thyroid stimulating autoantibody
-
Sanders J, Evans M, Premawardhana LDKE, Depraetere H, Jeffreys J, Richards T, Furmaniak J, Rees Smith B 2003 Human monoclonal thyroid stimulating autoantibody. Lancet 362:126-128.
-
(2003)
Lancet
, vol.362
, pp. 126-128
-
-
Sanders, J.1
Evans, M.2
Premawardhana, L.D.K.E.3
Depraetere, H.4
Jeffreys, J.5
Richards, T.6
Furmaniak, J.7
Rees Smith, B.8
-
6
-
-
0029645408
-
Modeling of the three-dimensional structure of proteins with the typical leucine-rich repeats
-
Kajava AV, Vassart G, Wodak SJ 1995 Modeling of the three-dimensional structure of proteins with the typical leucine-rich repeats. Structure 3:867-877.
-
(1995)
Structure
, vol.3
, pp. 867-877
-
-
Kajava, A.V.1
Vassart, G.2
Wodak, S.J.3
-
7
-
-
0029646089
-
Structural predictions for the ligand-binding region of glycoprotein hormone receptors and the nature of hormone-receptor interactions
-
Jiang X, Dreano M, Buckler DR, Cheng S, Ythier A, Wu H, Hendrickson WA, Tayar NE 1995 Structural predictions for the ligand-binding region of glycoprotein hormone receptors and the nature of hormone-receptor interactions. Structure 3:1341-1353.
-
(1995)
Structure
, vol.3
, pp. 1341-1353
-
-
Jiang, X.1
Dreano, M.2
Buckler, D.R.3
Cheng, S.4
Ythier, A.5
Wu, H.6
Hendrickson, W.A.7
Tayar, N.E.8
-
8
-
-
0031790855
-
A conserved tyrosine residue (Y601) in transmembrane domain 5 of the human thyrotropin receptor serves as a molecular switch to determine G-protein coupling
-
Biebermann H, Schoneberg T, Schulz A, Krause G, Gruters A, Schultz G, Gudermann T 1998 A conserved tyrosine residue (Y601) in transmembrane domain 5 of the human thyrotropin receptor serves as a molecular switch to determine G-protein coupling. FASEB J 12:1461-1471.
-
(1998)
FASEB J
, vol.12
, pp. 1461-1471
-
-
Biebermann, H.1
Schoneberg, T.2
Schulz, A.3
Krause, G.4
Gruters, A.5
Schultz, G.6
Gudermann, T.7
-
9
-
-
0034895145
-
A free carboxylate oxygen in the side chain of position 674 in transmembrane domain 7 is necessary for TSH receptor activation
-
Neumann S, Krause G, Chey S, Paschke R 2001 A free carboxylate oxygen in the side chain of position 674 in transmembrane domain 7 is necessary for TSH receptor activation. Mol Endocrinol 15:1294-1305.
-
(2001)
Mol Endocrinol
, vol.15
, pp. 1294-1305
-
-
Neumann, S.1
Krause, G.2
Chey, S.3
Paschke, R.4
-
10
-
-
0042021504
-
Thyrotropin receptor cleavage domain and tissue inhibitor of metalloproteinase-2
-
Miguel RN, Sanders J, Jeffreys J, Depraetere H, Blundell TL, Furmaniak J, Rees Smith B 2003 Thyrotropin receptor cleavage domain and tissue inhibitor of metalloproteinase-2. Thyroid 13:665-666.
-
(2003)
Thyroid
, vol.13
, pp. 665-666
-
-
Miguel, R.N.1
Sanders, J.2
Jeffreys, J.3
Depraetere, H.4
Blundell, T.L.5
Furmaniak, J.6
Rees Smith, B.7
-
11
-
-
0028941763
-
Monoclonal thyroglobulin autoantibodies: Variable region analysis and epitope recognition
-
Prentice L, Kiso Y, Fukuma N, Horimoto M, Petersen V, Grennan F, Pegg C, Furmaniak J, Rees Smith B 1995 Monoclonal thyroglobulin autoantibodies: Variable region analysis and epitope recognition. J Clin Endocrinol Metab 80:977-986.
-
(1995)
J Clin Endocrinol Metab
, vol.80
, pp. 977-986
-
-
Prentice, L.1
Kiso, Y.2
Fukuma, N.3
Horimoto, M.4
Petersen, V.5
Grennan, F.6
Pegg, C.7
Furmaniak, J.8
Rees Smith, B.9
-
12
-
-
0031978101
-
Binding characteristics of antibodies to the TSH receptor
-
Oda Y, Sanders J, Roberts S, Maruyama M, Kato R, Perez M, Petersen VB, Wedlock N, Furmaniak J, Rees Smith B 1998 Binding characteristics of antibodies to the TSH receptor. J Mol Endocrinol 20:233-244.
-
(1998)
J Mol Endocrinol
, vol.20
, pp. 233-244
-
-
Oda, Y.1
Sanders, J.2
Roberts, S.3
Maruyama, M.4
Kato, R.5
Perez, M.6
Petersen, V.B.7
Wedlock, N.8
Furmaniak, J.9
Rees Smith, B.10
-
13
-
-
0023277545
-
Single-step method of RNA isolation by guanidinium thiocyanate-phenol- chloroform extraction
-
Chomczynski P, Sacchi N 1987 Single-step method of RNA isolation by guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159.
-
(1987)
Anal Biochem
, vol.162
, pp. 156-159
-
-
Chomczynski, P.1
Sacchi, N.2
-
14
-
-
0027398107
-
Optimization of primers for cloning libraries of mouse immunoglobulin genes using the polymerase chain reaction
-
Kettleborough CA, Saldanha J, Ansell KH, Bendig MM 1993 Optimization of primers for cloning libraries of mouse immunoglobulin genes using the polymerase chain reaction. Eur J Immunol 23:206-211.
-
(1993)
Eur J Immunol
, vol.23
, pp. 206-211
-
-
Kettleborough, C.A.1
Saldanha, J.2
Ansell, K.H.3
Bendig, M.M.4
-
15
-
-
0033029907
-
Antigen sequence- and library-based mapping of linear and discontinuous protein-protein-interaction sites by spot synthesis
-
Reineke U, Kramer A, Schneider-Mergener J 1999 Antigen sequence- and library-based mapping of linear and discontinuous protein-protein-interaction sites by spot synthesis. Curr Top Microbiol Immunol 243:23-36.
-
(1999)
Curr Top Microbiol Immunol
, vol.243
, pp. 23-36
-
-
Reineke, U.1
Kramer, A.2
Schneider-Mergener, J.3
-
16
-
-
0019831147
-
The gene encoding the common alpha subunit of the four human glycoprotein hormones
-
Fiddes JC, Goodman HM 1981 The gene encoding the common alpha subunit of the four human glycoprotein hormones. J Mol Appl Genet 1:3-18.
-
(1981)
J Mol Appl Genet
, vol.1
, pp. 3-18
-
-
Fiddes, J.C.1
Goodman, H.M.2
-
17
-
-
0021101215
-
Characterization and nucleotide sequence of the gene for the common alpha subunit of the bovine pituitary glycoprotein hormones
-
Goodwin RG, Moncman CL, Rottman FM, Nilson JH 1983 Characterization and nucleotide sequence of the gene for the common alpha subunit of the bovine pituitary glycoprotein hormones. Nucleic Acids Res 11:6873-6882.
-
(1983)
Nucleic Acids Res
, vol.11
, pp. 6873-6882
-
-
Goodwin, R.G.1
Moncman, C.L.2
Rottman, F.M.3
Nilson, J.H.4
-
18
-
-
0021354399
-
The sequence of a cloned cDNA for the beta subunit of bovine thyrotropin predicts a protein containing both NH2- and COOH-terminal
-
Maurer RA, Croyle ML, Donelson JE 1984 The sequence of a cloned cDNA for the beta subunit of bovine thyrotropin predicts a protein containing both NH2- and COOH-terminal. J Biol Chem 259:5024-5027.
-
(1984)
J Biol Chem
, vol.259
, pp. 5024-5027
-
-
Maurer, R.A.1
Croyle, M.L.2
Donelson, J.E.3
-
19
-
-
0022178074
-
Molecular cloning of the human thyrotropin-beta subunit gene
-
Hayashizaki Y, Miyai K, Kato K, Matsubara K 1985 Molecular cloning of the human thyrotropin-beta subunit gene. FEBS Lett 188:394-400.
-
(1985)
FEBS Lett
, vol.188
, pp. 394-400
-
-
Hayashizaki, Y.1
Miyai, K.2
Kato, K.3
Matsubara, K.4
-
20
-
-
0024524615
-
Molecular cloning of cDNAs for precursors of porcine pituitary glycoprotein hormone common alpha-subunit and of thyroid stimulating hormone beta-subunit
-
Hirai T, Takikawa H, Kato Y 1989 Molecular cloning of cDNAs for precursors of porcine pituitary glycoprotein hormone common alpha-subunit and of thyroid stimulating hormone beta-subunit. Mol Cell Endocrinol 63:209-217.
-
(1989)
Mol Cell Endocrinol
, vol.63
, pp. 209-217
-
-
Hirai, T.1
Takikawa, H.2
Kato, Y.3
-
21
-
-
0030801002
-
Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
-
Altschul SF, Madden TL, Schaffer AA, Zhang J, Zhang Z, Miller W, Lipman DJ 1997 Gapped BLAST and PSI-BLAST: A new generation of protein database search programs. Nucleic Acids Res 25:3389-3402.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 3389-3402
-
-
Altschul, S.F.1
Madden, T.L.2
Schaffer, A.A.3
Zhang, J.4
Zhang, Z.5
Miller, W.6
Lipman, D.J.7
-
22
-
-
0029913807
-
An evolutionary trace method defines binding surfaces common to protein families
-
Lichtarge O, Bourne HR, Cohen FE 1996 An evolutionary trace method defines binding surfaces common to protein families. J Mol Biol 257:342-358.
-
(1996)
J Mol Biol
, vol.257
, pp. 342-358
-
-
Lichtarge, O.1
Bourne, H.R.2
Cohen, F.E.3
-
23
-
-
0034459679
-
Evolutionary trace analysis of TGB-β and related growth factors: Implications for site-directed mutagenesis
-
Innis CA, Shi J, Blundell TL 2000 Evolutionary trace analysis of TGB-β and related growth factors: Implications for site-directed mutagenesis. Protein Eng 13:839-847.
-
(2000)
Protein Eng
, vol.13
, pp. 839-847
-
-
Innis, C.A.1
Shi, J.2
Blundell, T.L.3
-
24
-
-
0028773646
-
Structure of human chorionic gonadotropin at 2.6 angstroms resolution from MAD analysis of the selenomethionyl protein
-
Wu H, Lustbader JW, Liu Y, Canfield RE, Hendrickson WA 1994 Structure of human chorionic gonadotropin at 2.6 angstroms resolution from MAD analysis of the selenomethionyl protein. Structure 2:545-558.
-
(1994)
Structure
, vol.2
, pp. 545-558
-
-
Wu, H.1
Lustbader, J.W.2
Liu, Y.3
Canfield, R.E.4
Hendrickson, W.A.5
-
25
-
-
0035105355
-
Three-dimensional structure of human follicle-stimulating hormone
-
Fox KM, Dias JA, vanRoey P 2001 Three-dimensional structure of human follicle-stimulating hormone. Mol Endocrinol 15:378-389.
-
(2001)
Mol Endocrinol
, vol.15
, pp. 378-389
-
-
Fox, K.M.1
Dias, J.A.2
Vanroey, P.3
-
26
-
-
0024852495
-
Molecular cloning, sequence and functional expression of the cDNA for the human thyrotropin receptor
-
Nagayama Y, Kaufman KD, Seto P, Rapoport B 1989 Molecular cloning, sequence and functional expression of the cDNA for the human thyrotropin receptor. Biochem Biophys Res Commun 165:1184-1190.
-
(1989)
Biochem Biophys Res Commun
, vol.165
, pp. 1184-1190
-
-
Nagayama, Y.1
Kaufman, K.D.2
Seto, P.3
Rapoport, B.4
-
27
-
-
0025022499
-
Cloning, sequencing and expression of human TSH receptor
-
Misrahi M, Loosfelt H, Atger M, Sar S, Guiochon-Mantel A, Milgrom E 1990 Cloning, sequencing and expression of human TSH receptor. Biochem Biophys Res Commun 166:394-403.
-
(1990)
Biochem Biophys Res Commun
, vol.166
, pp. 394-403
-
-
Misrahi, M.1
Loosfelt, H.2
Atger, M.3
Sar, S.4
Guiochon-Mantel, A.5
Milgrom, E.6
-
28
-
-
0033654768
-
Hybrid fold recognition: Combining sequence derived properties with evolutionary information
-
January 4-9, 2000, Island of Oahu, Hawaii
-
Fischer D 2000 Hybrid fold recognition: combining sequence derived properties with evolutionary information. In: Pacific Symp Biocomputing, January 4-9, 2000, Island of Oahu, Hawaii, pp. 119-130.
-
(2000)
Pacific Symp Biocomputing
, pp. 119-130
-
-
Fischer, D.1
-
29
-
-
0035967880
-
FUGUE: Sequence-structure homology recognition using environment-specific substitution tables and structure-dependent gap penalties
-
Shi J, Blundell TL, Mizuguchi K 2001 FUGUE: sequence-structure homology recognition using environment-specific substitution tables and structure-dependent gap penalties. J Mol Biol 310:243-257.
-
(2001)
J Mol Biol
, vol.310
, pp. 243-257
-
-
Shi, J.1
Blundell, T.L.2
Mizuguchi, K.3
-
30
-
-
0027136282
-
Comparative protein modeling by satisfaction of spatial restraints
-
Sali A, Blundell TL 1993 Comparative protein modeling by satisfaction of spatial restraints. J Mol Biol 234:779-815.
-
(1993)
J Mol Biol
, vol.234
, pp. 779-815
-
-
Sali, A.1
Blundell, T.L.2
-
32
-
-
0026610767
-
Assessment of protein models with 3-dimensional profiles
-
Luthy R, Bowie JU, Eisenberg D 1992 Assessment of protein models with 3-dimensional profiles. Nature 356:83-85.
-
(1992)
Nature
, vol.356
, pp. 83-85
-
-
Luthy, R.1
Bowie, J.U.2
Eisenberg, D.3
-
33
-
-
0031714858
-
JOY: Protein sequence-structure representation and analysis
-
Mizuguchi K, Deane CM, Blundell TL, Johnson MS, Overington JP 1998 JOY: Protein sequence-structure representation and analysis. Bioinformatics 14:617-623.
-
(1998)
Bioinformatics
, vol.14
, pp. 617-623
-
-
Mizuguchi, K.1
Deane, C.M.2
Blundell, T.L.3
Johnson, M.S.4
Overington, J.P.5
-
34
-
-
0035107308
-
CODA: A combined algorithm for predicting the structurally variable regions of protein models
-
Deane CM, Blundell TL 2001 CODA: A combined algorithm for predicting the structurally variable regions of protein models. Protein Sci 10:599-612.
-
(2001)
Protein Sci
, vol.10
, pp. 599-612
-
-
Deane, C.M.1
Blundell, T.L.2
-
35
-
-
0037375615
-
Ab initio construction of polypeptide fragments: Accuracy of loop decoy discrimination by an all-atom statistical potential and the AMBER force field with Generalized Born solvation model
-
de Bakker PI, DePristo MA, Burke DF, Blundell TL 2003 Ab initio construction of polypeptide fragments: Accuracy of loop decoy discrimination by an all-atom statistical potential and the AMBER force field with Generalized Born solvation model. Proteins Struct Funct Genet 51:21-40.
-
(2003)
Proteins Struct Funct Genet
, vol.51
, pp. 21-40
-
-
De Bakker, P.I.1
DePristo, M.A.2
Burke, D.F.3
Blundell, T.L.4
-
36
-
-
0037375742
-
Ab initio construction of polypeptide fragments: Efficient generation of consistent, representative ensembles
-
DePristo MA, deBakker PIW, Lovell SC, Blundell TL 2003 Ab initio construction of polypeptide fragments: Efficient generation of consistent, representative ensembles. Proteins Struct Funct Genet 51:41-55.
-
(2003)
Proteins Struct Funct Genet
, vol.51
, pp. 41-55
-
-
DePristo, M.A.1
DeBakker, P.I.W.2
Lovell, S.C.3
Blundell, T.L.4
-
37
-
-
11344292435
-
-
Trypos Inc., St Louis, MO
-
SYBYL 1997 6.5 edition. Trypos Inc., St Louis, MO.
-
SYBYL 1997 6.5 Edition
-
-
-
39
-
-
0015222647
-
The interpretation of protein structures: Estimation of static accessibility
-
Lee B, Richards FM 1971 The interpretation of protein structures: Estimation of static accessibility. J Mol Biol 55:379-400.
-
(1971)
J Mol Biol
, vol.55
, pp. 379-400
-
-
Lee, B.1
Richards, F.M.2
-
40
-
-
0021755764
-
Solvent accessible surface area and excluded volume in proteins. Analytical equations for overlapping spheres and implications for the hydrophobic effect
-
Richmond TJ 1984 Solvent accessible surface area and excluded volume in proteins. Analytical equations for overlapping spheres and implications for the hydrophobic effect. J Mol Biol 178:63-89.
-
(1984)
J Mol Biol
, vol.178
, pp. 63-89
-
-
Richmond, T.J.1
-
41
-
-
0028304962
-
Satisfying hydrogen bonding potential in proteins
-
McDonald IK, Thornton JM 1994 Satisfying hydrogen bonding potential in proteins. J Mol Biol 238:777-793.
-
(1994)
J Mol Biol
, vol.238
, pp. 777-793
-
-
McDonald, I.K.1
Thornton, J.M.2
-
42
-
-
0026319199
-
Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons
-
Nicholls A, Sharp K, Honing B 1991 Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons. Proteins 11:281-296.
-
(1991)
Proteins
, vol.11
, pp. 281-296
-
-
Nicholls, A.1
Sharp, K.2
Honing, B.3
-
43
-
-
0001433241
-
Knowledge based modeling of homologous proteins, part I: Three-dimensional frameworks derived from the simultaneous superposition of multiple structures
-
Sutcliffe MJ, Haneef I, Carney D, Blundell TL 1987 Knowledge based modeling of homologous proteins, part I: Three-dimensional frameworks derived from the simultaneous superposition of multiple structures. Protein Eng 1:377-384.
-
(1987)
Protein Eng
, vol.1
, pp. 377-384
-
-
Sutcliffe, M.J.1
Haneef, I.2
Carney, D.3
Blundell, T.L.4
-
44
-
-
0026572775
-
Molecular surface recognition: Determination of geometric fit between proteins and their ligands by correlation techniques
-
Katchalski-Katzir E, Shariv I, Eisestein M, Friesem AA, Aflalo C, Vakser IA 1992 Molecular surface recognition: Determination of geometric fit between proteins and their ligands by correlation techniques. Proc Natl Acad Sci USA 89:2195-2199.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 2195-2199
-
-
Katchalski-Katzir, E.1
Shariv, I.2
Eisestein, M.3
Friesem, A.A.4
Aflalo, C.5
Vakser, I.A.6
-
46
-
-
0034505940
-
Epitope analysis of the human monoclonal thyrotropin (TSH) receptor using monoclonal antibodies
-
Oda Y, Sanders J, Evans M, Kiddie A, Munkley A, James C, Richards T, Wills J, Furmaniak J, Rees Smith B 2000 Epitope analysis of the human monoclonal thyrotropin (TSH) receptor using monoclonal antibodies. Thyroid 10:1051-1059.
-
(2000)
Thyroid
, vol.10
, pp. 1051-1059
-
-
Oda, Y.1
Sanders, J.2
Evans, M.3
Kiddie, A.4
Munkley, A.5
James, C.6
Richards, T.7
Wills, J.8
Furmaniak, J.9
Rees Smith, B.10
-
47
-
-
0004032583
-
-
U.S. Public Health Service, Bethesda, MD
-
Kabat E, Perry H, Wu T, Gottesman K, Foeller C 1991 Sequences of Proteins of Immunological Interest, 5th ed. U.S. Public Health Service, Bethesda, MD.
-
(1991)
Sequences of Proteins of Immunological Interest, 5th Ed.
-
-
Kabat, E.1
Perry, H.2
Wu, T.3
Gottesman, K.4
Foeller, C.5
-
48
-
-
0027251256
-
A structural superfamily of growth factors containing & cystine knot motif
-
McDonald NQ, Hendrickson WA 1993 A structural superfamily of growth factors containing & cystine knot motif. Cell 73:421-424.
-
(1993)
Cell
, vol.73
, pp. 421-424
-
-
McDonald, N.Q.1
Hendrickson, W.A.2
-
49
-
-
0027918158
-
Topological similarities in TGF-beta 2, PDGF-BB and NGF define a superfamily of polypeptide growth factors
-
Murray-Rust J, McDonald NQ, Blundell TL, Hosang M, Oefner C, Winkler F, Bradshaw RA 1993 Topological similarities in TGF-beta 2, PDGF-BB and NGF define a superfamily of polypeptide growth factors. Structure 1:153-159.
-
(1993)
Structure
, vol.1
, pp. 153-159
-
-
Murray-Rust, J.1
McDonald, N.Q.2
Blundell, T.L.3
Hosang, M.4
Oefner, C.5
Winkler, F.6
Bradshaw, R.A.7
-
50
-
-
0030437795
-
Structural and functional diversity in the leucine-rich repeat family of proteins
-
Buchanan SG, Gay NJ 1996 Structural and functional diversity in the leucine-rich repeat family of proteins. Prog Biophys Mol Biol 65:1-44.
-
(1996)
Prog Biophys Mol Biol
, vol.65
, pp. 1-44
-
-
Buchanan, S.G.1
Gay, N.J.2
-
51
-
-
0027718173
-
Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats
-
Kobe B, Deisenhofer J 1993 Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats. Nature 366:751-756.
-
(1993)
Nature
, vol.366
, pp. 751-756
-
-
Kobe, B.1
Deisenhofer, J.2
-
52
-
-
0032898172
-
Sequential cleavage and excision of a segment of the thyrotropin receptor ectodomain
-
de Bernard S, Misrahi M, J-C H, Milgrom E 1999 Sequential cleavage and excision of a segment of the thyrotropin receptor ectodomain. J Biol Chem 274:101-107.
-
(1999)
J Biol Chem
, vol.274
, pp. 101-107
-
-
De Bernard, S.1
Misrahi, M.2
H., J.-C.3
Milgrom, E.4
-
53
-
-
0032509104
-
Three-dimensional structure of human tissue inhibitor of metalloproteinases-2 at 2.1 Å resolution
-
Tuuttila A, Morgunova E, Bergmann U, Lindqvist Y, Tryggvason K, Schneider G 1998 Three-dimensional structure of human tissue inhibitor of metalloproteinases-2 at 2.1 Å resolution. J Mol Biol 284:1133-1140.
-
(1998)
J Mol Biol
, vol.284
, pp. 1133-1140
-
-
Tuuttila, A.1
Morgunova, E.2
Bergmann, U.3
Lindqvist, Y.4
Tryggvason, K.5
Schneider, G.6
-
54
-
-
0027479161
-
OB (oligonucleotide/oligosaccharide binding)-fold: Common structural and functional solution for non-homologous sequences
-
Murzin AG 1993 OB (oligonucleotide/oligosaccharide binding)-fold: Common structural and functional solution for non-homologous sequences. EMBO J 12:861-867.
-
(1993)
EMBO J
, vol.12
, pp. 861-867
-
-
Murzin, A.G.1
-
55
-
-
0034604451
-
Crystal structure of rhodopsin: A G protein-coupled receptor
-
Palczewski K, Kamusaka T, Hori T, Behnke CA, Motoshima H, Fox BA, LeTrong I, Teller DC, Okada T, Stenkamp RE, Yamamoto M, Miyano M 2000 Crystal structure of rhodopsin: A G protein-coupled receptor. Science 289:739-745.
-
(2000)
Science
, vol.289
, pp. 739-745
-
-
Palczewski, K.1
Kamusaka, T.2
Hori, T.3
Behnke, C.A.4
Motoshima, H.5
Fox, B.A.6
LeTrong, I.7
Teller, D.C.8
Okada, T.9
Stenkamp, R.E.10
Yamamoto, M.11
Miyano, M.12
-
56
-
-
0037197848
-
Functional role of internal water molecules in rhodopsin revealed by x-ray crystallography
-
Okada T, Fujiyoshi Y, Silow M, Navarro J, Landau EM, Shichida Y 2002 Functional role of internal water molecules in rhodopsin revealed by x-ray crystallography. Proc Natl Acad Sci USA 95:12854-12859.
-
(2002)
Proc Natl Acad Sci USA
, vol.95
, pp. 12854-12859
-
-
Okada, T.1
Fujiyoshi, Y.2
Silow, M.3
Navarro, J.4
Landau, E.M.5
Shichida, Y.6
-
57
-
-
0038010379
-
3 Cytoplasmatic loops of rhodopsin interact with transducin
-
Konig B, Arendt A, McDowell JH, Kahlert M, Hargrave PA, Hofmann KP 1989 3 Cytoplasmatic loops of rhodopsin interact with transducin. Proc Natl Acad Sci USA 86:6878-6882.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 6878-6882
-
-
Konig, B.1
Arendt, A.2
McDowell, J.H.3
Kahlert, M.4
Hargrave, P.A.5
Hofmann, K.P.6
-
58
-
-
0031576997
-
Three-dimensional structure of an Fab-peptide complex: Structural basis of HIV-1 protease inhibition by a monoclonal antibody
-
Lescar J, Stouracova R, Riottot MM, Chitarra V, Brynda J, Fabry M, Horejsi M, Sedlacek J, Bentley GA 1997 Three-dimensional structure of an Fab-peptide complex: Structural basis of HIV-1 protease inhibition by a monoclonal antibody. J Mol Biol 267:1207-1222.
-
(1997)
J Mol Biol
, vol.267
, pp. 1207-1222
-
-
Lescar, J.1
Stouracova, R.2
Riottot, M.M.3
Chitarra, V.4
Brynda, J.5
Fabry, M.6
Horejsi, M.7
Sedlacek, J.8
Bentley, G.A.9
-
59
-
-
0034730118
-
Structural evidence for a programmed general base in the active site of a catalytic antibody
-
Golinelli-Pimpaneau B, Goncalves O, Dintinger T, Blanchard D, Knossow M, Tellier C 2000 Structural evidence for a programmed general base in the active site of a catalytic antibody. Proc Natl Acad Sci USA 97:9892-9895.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 9892-9895
-
-
Golinelli-Pimpaneau, B.1
Goncalves, O.2
Dintinger, T.3
Blanchard, D.4
Knossow, M.5
Tellier, C.6
-
60
-
-
0029785186
-
Engineering human glycoprotein hormone superactive analogues
-
Szkudlinski MW, Teh NG, Grossmann M, Tropea JE, Weintraub BD 1996 Engineering human glycoprotein hormone superactive analogues. Nature Biotech 14:1257-1263.
-
(1996)
Nature Biotech
, vol.14
, pp. 1257-1263
-
-
Szkudlinski, M.W.1
Teh, N.G.2
Grossmann, M.3
Tropea, J.E.4
Weintraub, B.D.5
-
61
-
-
0030805829
-
Constitutive activation of the TSH receptor by spontaneous mutations affecting the N-terminal extracellular domain
-
Duprez L, Parma J, Costagliola S, Hermans J, Van-Sande J, Dumont JE, Vassart G 1997 Constitutive activation of the TSH receptor by spontaneous mutations affecting the N-terminal extracellular domain. FEBS Letters 409:469-474.
-
(1997)
FEBS Letters
, vol.409
, pp. 469-474
-
-
Duprez, L.1
Parma, J.2
Costagliola, S.3
Hermans, J.4
Van-Sande, J.5
Dumont, J.E.6
Vassart, G.7
-
62
-
-
0031772403
-
Severe congenital hyperthyroidism caused by a germ-line neo mutation in the extracellular portion of the thyrotropin receptor
-
Gruters A, Schoneberg T, Biebermann H, Krude H, Krohn HP, Dralle H, Gudermann T 1998 Severe congenital hyperthyroidism caused by a germ-line neo mutation in the extracellular portion of the thyrotropin receptor. J Clin Endocrinol Metab 83:1431-1436.
-
(1998)
J Clin Endocrinol Metab
, vol.83
, pp. 1431-1436
-
-
Gruters, A.1
Schoneberg, T.2
Biebermann, H.3
Krude, H.4
Krohn, H.P.5
Dralle, H.6
Gudermann, T.7
-
63
-
-
0036083401
-
Thyroid-stimulating hormone and thyroid-stimulating hormone receptor structure-function relationships
-
Szkudlinski MW, Fremont V, Ronin C, Weintraub BD 2002 Thyroid-stimulating hormone and thyroid-stimulating hormone receptor structure-function relationships. Physiol Rev 82:473-502.
-
(2002)
Physiol Rev
, vol.82
, pp. 473-502
-
-
Szkudlinski, M.W.1
Fremont, V.2
Ronin, C.3
Weintraub, B.D.4
-
64
-
-
0036214718
-
Activation of the cAMP pathway by the TSH receptor involves switching of the ectodomain from a tethered inverse agonist to an agonist
-
Vlaeminck-Guillem V, Ho S-C, Rodien P, Vassart G, Costagliola S 2002 Activation of the cAMP pathway by the TSH receptor involves switching of the ectodomain from a tethered inverse agonist to an agonist. Mol Endocrinol 16:736-746.
-
(2002)
Mol Endocrinol
, vol.16
, pp. 736-746
-
-
Vlaeminck-Guillem, V.1
Ho, S.-C.2
Rodien, P.3
Vassart, G.4
Costagliola, S.5
-
65
-
-
0036218255
-
Lysine 183 and glutamic acid 157 of the TSH receptor: Two interacting residues with a key role in determining specificity toward TSH and human CG
-
Smits G, Govaerts C, Nubourgh I, Pardo L, Vassart G, Costagliola S 2002 Lysine 183 and glutamic acid 157 of the TSH receptor: Two interacting residues with a key role in determining specificity toward TSH and human CG. Mol Endocrinol 16:722-735.
-
(2002)
Mol Endocrinol
, vol.16
, pp. 722-735
-
-
Smits, G.1
Govaerts, C.2
Nubourgh, I.3
Pardo, L.4
Vassart, G.5
Costagliola, S.6
-
66
-
-
84986512474
-
CHARMM: A program for macromolecular energy minimisation and dynamics calculations
-
Brooks BR, Bruccolesi RE, Olafson BD, States DJ, Swaminathan S, Karplus M 1983 CHARMM: A program for macromolecular energy minimisation and dynamics calculations. J Comp Chem 4:187-217.
-
(1983)
J Comp Chem
, vol.4
, pp. 187-217
-
-
Brooks, B.R.1
Bruccolesi, R.E.2
Olafson, B.D.3
States, D.J.4
Swaminathan, S.5
Karplus, M.6
-
68
-
-
0032478536
-
Structural diversity of leucine-rich repeat proteins
-
Kajava AV 1998 Structural diversity of leucine-rich repeat proteins. J Mol Biol 277:519-527.
-
(1998)
J Mol Biol
, vol.277
, pp. 519-527
-
-
Kajava, A.V.1
-
69
-
-
0035805619
-
A full biological response to autoantibodies in Graves' disease requires a disulfide-bonded loop in the thyrotropin receptor N terminus homologous to a laminin epidermal growth factor-like domain
-
Chen C-R, Tanaka K, Chazenbalk GD, McLachlan SM, Rapoport B 2001 A full biological response to autoantibodies in Graves' disease requires a disulfide-bonded loop in the thyrotropin receptor N terminus homologous to a laminin epidermal growth factor-like domain. J Biol Chem 276:14767-14772.
-
(2001)
J Biol Chem
, vol.276
, pp. 14767-14772
-
-
Chen, C.-R.1
Tanaka, K.2
Chazenbalk, G.D.3
McLachlan, S.M.4
Rapoport, B.5
-
70
-
-
0028080261
-
The leucine-rich repeat: A versatile binding motif
-
Kobe B, Deisenhofer J 1994 The leucine-rich repeat: A versatile binding motif. Trends Biochem Sci 19:415-421.
-
(1994)
Trends Biochem Sci
, vol.19
, pp. 415-421
-
-
Kobe, B.1
Deisenhofer, J.2
-
71
-
-
0031916977
-
The luteinizing hormone receptor
-
Dufau ML 1998 The luteinizing hormone receptor. Annu Rev Physiol 60:461-496.
-
(1998)
Annu Rev Physiol
, vol.60
, pp. 461-496
-
-
Dufau, M.L.1
-
74
-
-
0035663195
-
Thyrotropin receptor mutations as a tool to understand thyrotropin receptor action
-
Wonerow P, Neumann S, Gudermann T, Paschke R 2001 Thyrotropin receptor mutations as a tool to understand thyrotropin receptor action. J Mol Med 79:707-721.
-
(2001)
J Mol Med
, vol.79
, pp. 707-721
-
-
Wonerow, P.1
Neumann, S.2
Gudermann, T.3
Paschke, R.4
-
75
-
-
0037165664
-
A conserved Asn in TM7 of the thyrotropin receptor is a common requirement for activation by both mutations and its natural agonist
-
Claeysen S, Govaerts C, Lefort A, Van Sande J, Costagliola S, Pardo L, Vassart G 2002 A conserved Asn in TM7 of the thyrotropin receptor is a common requirement for activation by both mutations and its natural agonist. FEBS Lett 517:196-200.
-
(2002)
FEBS Lett
, vol.517
, pp. 196-200
-
-
Claeysen, S.1
Govaerts, C.2
Lefort, A.3
Van Sande, J.4
Costagliola, S.5
Pardo, L.6
Vassart, G.7
-
76
-
-
0038182549
-
Glycoprotein hormone receptors: Determinants in leucine-rich repeats responsible for ligand specificity
-
Smits G, Campillo M, Govaerts C, Janssens V, Richter C, Vassart G, Pardo L, Costagliola S 2003 Glycoprotein hormone receptors: Determinants in leucine-rich repeats responsible for ligand specificity. EMBO J 22:2692-2703.
-
(2003)
EMBO J
, vol.22
, pp. 2692-2703
-
-
Smits, G.1
Campillo, M.2
Govaerts, C.3
Janssens, V.4
Richter, C.5
Vassart, G.6
Pardo, L.7
Costagliola, S.8
-
77
-
-
0030013815
-
Site-directed mutagenesis of amino acids 33-44 of the common alpha-subunit reveals different structural requirements for heterodimer expression among the glycoprotein hormones and suggests that cyclic adenosine 3′,5′-monophosphate production and growth promotion are potentially dissociable functions of human thyrotropin
-
Grossmann M, Szkudlinski MW, Dias JA, Xia HY, Wong R, Puett D, Weintraub BD 1996 Site-directed mutagenesis of amino acids 33-44 of the common alpha-subunit reveals different structural requirements for heterodimer expression among the glycoprotein hormones and suggests that cyclic adenosine 3′,5′-monophosphate production and growth promotion are potentially dissociable functions of human thyrotropin. Mol Endocrinol 10:769-779.
-
(1996)
Mol Endocrinol
, vol.10
, pp. 769-779
-
-
Grossmann, M.1
Szkudlinski, M.W.2
Dias, J.A.3
Xia, H.Y.4
Wong, R.5
Puett, D.6
Weintraub, B.D.7
-
78
-
-
0037084011
-
Tyrosine sulfation is required for agonist recognition by glycoprotein hormone receptors
-
Costagliola S, Panneels V, Bonomi M, Koch J, Many MC, Smits G, Vassart G 2002 Tyrosine sulfation is required for agonist recognition by glycoprotein hormone receptors. EMBO J 21:504-513.
-
(2002)
EMBO J
, vol.21
, pp. 504-513
-
-
Costagliola, S.1
Panneels, V.2
Bonomi, M.3
Koch, J.4
Many, M.C.5
Smits, G.6
Vassart, G.7
-
79
-
-
0035976910
-
Oligomerization of the human thyrotropin receptor
-
Latif R, Graves P, Davies TF 2001 Oligomerization of the human thyrotropin receptor. J Biol Chem 276:45217-45224.
-
(2001)
J Biol Chem
, vol.276
, pp. 45217-45224
-
-
Latif, R.1
Graves, P.2
Davies, T.F.3
-
81
-
-
0037388637
-
Evolution of the thyrotropin receptor: A G protein coupled receptor with an intrinsic capacity to dimerize
-
Kaczur V, Puskás LG, Takács M, Rácz IA, Szendröi A, Tóth S, Nagy Z, Szalai C, Balázs C, Falus A, Knudsen B, Farid N 2003 Evolution of the thyrotropin receptor: A G protein coupled receptor with an intrinsic capacity to dimerize. Mol Genet Metab 78:275-290.
-
(2003)
Mol Genet Metab
, vol.78
, pp. 275-290
-
-
Kaczur, V.1
Puskás, L.G.2
Takács, M.3
Rácz, I.A.4
Szendröi, A.5
Tóth, S.6
Nagy, Z.7
Szalai, C.8
Balázs, C.9
Falus, A.10
Knudsen, B.11
Farid, N.12
-
82
-
-
0037426865
-
Rhodopsin dimers in native disc membranes
-
Fotiadis D, Liang Y, Filipek S, Saperstein DA, Engel A, Palczewski K 2003 Rhodopsin dimers in native disc membranes. Nature 421:127-128.
-
(2003)
Nature
, vol.421
, pp. 127-128
-
-
Fotiadis, D.1
Liang, Y.2
Filipek, S.3
Saperstein, D.A.4
Engel, A.5
Palczewski, K.6
-
83
-
-
0025275610
-
On the nature of antibody combining sites: Unusual structural features that may confer on these sites an enhanced capacity for binding ligands
-
Padlan EA 1990 On the nature of antibody combining sites: Unusual structural features that may confer on these sites an enhanced capacity for binding ligands. Proteins 7:112-124.
-
(1990)
Proteins
, vol.7
, pp. 112-124
-
-
Padlan, E.A.1
-
84
-
-
85047699286
-
X-ray crystal structure of a monoclonal antibody that binds to a major autoantigenic epitope on thyroid peroxidase
-
Hendry E, Taylor G, Grennan-Jones F, Sullivan A, Liddy N, Godfrey J, Hayakawa N, Powell M, Sanders J, Furmaniak J, Rees Smith B 2001 X-ray crystal structure of a monoclonal antibody that binds to a major autoantigenic epitope on thyroid peroxidase. Thyroid 11:1091-1099.
-
(2001)
Thyroid
, vol.11
, pp. 1091-1099
-
-
Hendry, E.1
Taylor, G.2
Grennan-Jones, F.3
Sullivan, A.4
Liddy, N.5
Godfrey, J.6
Hayakawa, N.7
Powell, M.8
Sanders, J.9
Furmaniak, J.10
Rees Smith, B.11
-
85
-
-
0034457935
-
The extracellular domain suppresses constitutive activity of the transmembrane domain of the human TSH receptor: Implications for hormonereceptor interaction and antagonist design
-
Zhang M, Tong K, Fremont V, Chen J, Narayan P, Puett D, Weintraub B, Szkudlinski M 2000 The extracellular domain suppresses constitutive activity of the transmembrane domain of the human TSH receptor: Implications for hormonereceptor interaction and antagonist design. Endocrinology 141:3514-3517.
-
(2000)
Endocrinology
, vol.141
, pp. 3514-3517
-
-
Zhang, M.1
Tong, K.2
Fremont, V.3
Chen, J.4
Narayan, P.5
Puett, D.6
Weintraub, B.7
Szkudlinski, M.8
-
86
-
-
0042421851
-
Evidence that the C terminus of the A subunit suppresses thyrotropin receptor constitutive activity
-
Chen C-R, Chazenbalk GD, McLachlan SM, Rapoport B 2003 Evidence that the C terminus of the A subunit suppresses thyrotropin receptor constitutive activity. Endocrinology 144:3821-3827.
-
(2003)
Endocrinology
, vol.144
, pp. 3821-3827
-
-
Chen, C.-R.1
Chazenbalk, G.D.2
McLachlan, S.M.3
Rapoport, B.4
-
87
-
-
0035748718
-
Sequence-structure homology recognition by iterative alignment refinement and comparative modelling
-
Williams MG, Shirai H, Shi J, Nagendra HG, Mueller J, Mizuguchi K, Miguel RN, Lovell SC, Innis CA, Deane CM, Chen L, Campillo N, Burke DF, Blundell TL, de Bakker PIW 2001 Sequence-structure homology recognition by iterative alignment refinement and comparative modelling. Proteins Suppl 5:92-97.
-
(2001)
Proteins Suppl
, vol.5
, pp. 92-97
-
-
Williams, M.G.1
Shirai, H.2
Shi, J.3
Nagendra, H.G.4
Mueller, J.5
Mizuguchi, K.6
Miguel, R.N.7
Lovell, S.C.8
Innis, C.A.9
Deane, C.M.10
Chen, L.11
Campillo, N.12
Burke, D.F.13
Blundell, T.L.14
De Bakker, P.I.W.15
-
88
-
-
11344261080
-
Protein Fold Recognition and Comparative Modeling using HOSTRAD, JOY and FUGUE
-
Tsigelny I (ed) International University Line (IUL), La Jolla
-
Miguel RN, Shi J, Mizuguchi K 2001 Protein Fold Recognition and Comparative Modeling using HOSTRAD, JOY and FUGUE. In: Tsigelny I (ed) Protein Structure Prediction: Bioinformatic Approach. International University Line (IUL), La Jolla, pp. 143-169.
-
(2001)
Protein Structure Prediction: Bioinformatic Approach
, pp. 143-169
-
-
Miguel, R.N.1
Shi, J.2
Mizuguchi, K.3
|