-
1
-
-
64949154427
-
Synthesis of novel bis-heterocycles: Bis pyrroles, pyrrolyl pyrazolines and pyrrolyl isoxazolines
-
Padmavathi, V.; Radhalakshmi, T.; Mahesh, K.; Mohan, A. V. N. Synthesis of novel bis-heterocycles: Bis pyrroles, pyrrolyl pyrazolines and pyrrolyl isoxazolines. Indian J. Chem. 2008, 47B, 1707-1712.
-
(2008)
Indian J. Chem
, vol.47 B
, pp. 1707-1712
-
-
Padmavathi, V.1
Radhalakshmi, T.2
Mahesh, K.3
Mohan, A.V.N.4
-
2
-
-
84888036558
-
Piperazine-pyrazine and their multiple biological activities
-
Meher, C. P.; Rao, A. M.; Omar, M. Piperazine-pyrazine and their multiple biological activities. Asian J. Pharm. Sci. Res. 2013, 3, 43-60.
-
(2013)
Asian J. Pharm. Sci. Res
, vol.3
, pp. 43-60
-
-
Meher, C.P.1
Rao, A.M.2
Omar, M.3
-
3
-
-
84872820836
-
A valuable insight into recent advances on antimicrobial activity of piperazine Derivatives
-
Kharb, R.; Bansal, K.; Sharma, A. K. A valuable insight into recent advances on antimicrobial activity of piperazine Derivatives. Der Pharm. Chem. 2012, 4, 2470-2488.
-
(2012)
Der Pharm. Chem
, vol.4
, pp. 2470-2488
-
-
Kharb, R.1
Bansal, K.2
Sharma, A.K.3
-
4
-
-
84875228758
-
Copper(II) triflate promoted multicomponent catalytic clubbing of piperazinylthiazoloquinolines and thiazolocoumarins as antimicrobials
-
Patel, R. V.; Patel, J. K.; Nile, S. H.; Park, S. W. Copper(II) triflate promoted multicomponent catalytic clubbing of piperazinylthiazoloquinolines and thiazolocoumarins as antimicrobials. Arch. Pharm. Chem. Life Sci. 2013, 346, 221-231.
-
(2013)
Arch. Pharm. Chem. Life Sci
, vol.346
, pp. 221-231
-
-
Patel, R.V.1
Patel, J.K.2
Nile, S.H.3
Park, S.W.4
-
5
-
-
84879773263
-
Green construction of fluoro/methoxy phenyl piperazinyl-2-(benzo)thiophen/furan-2-yl-acetonitriles: Strecker reaction products as antimicrobial agents
-
Patel, R. V.; Patel, J. K.; Nile, S. H.; Park, S. W. Green construction of fluoro/methoxy phenyl piperazinyl-2-(benzo)thiophen/furan-2-yl-acetonitriles: Strecker reaction products as antimicrobial agents. Lett. Drug Des. Dis. 2013, 10, 462-470.
-
(2013)
Lett. Drug Des. Dis
, vol.10
, pp. 462-470
-
-
Patel, R.V.1
Patel, J.K.2
Nile, S.H.3
Park, S.W.4
-
6
-
-
84865804105
-
Synthesis of novel quinolone and coumarin based 1, 3, 4-thiazdiazolyl and 1, 3, 4-oxadiazolyl N-Mannich bases as potential antimicrobials
-
Patel, R. V.; Patel, J. K.; Kumari, P.; Chikhalia, K. H. Synthesis of novel quinolone and coumarin based 1, 3, 4-thiazdiazolyl and 1, 3, 4-oxadiazolyl N-Mannich bases as potential antimicrobials. Lett. Org. Chem. 2012, 9, 478-486.
-
(2012)
Lett. Org. Chem
, vol.9
, pp. 478-486
-
-
Patel, R.V.1
Patel, J.K.2
Kumari, P.3
Chikhalia, K.H.4
-
7
-
-
84872014856
-
Synthesis of coumarin based 1, 3, 4-oxadiazol-2ylthio-N-phenyl (benzothiazolyl) acetamides as antimicrobial and antituberculosis agents
-
Patel, R. V.; Patel, A. B.; Kumari, P.; Chikhalia, K. H. Synthesis of coumarin based 1, 3, 4-oxadiazol-2ylthio-N-phenyl (benzothiazolyl) acetamides as antimicrobial and antituberculosis agents. Med. Chem. Res. 2013, 22, 195-210.
-
(2013)
Med. Chem. Res
, vol.22
, pp. 195-210
-
-
Patel, R.V.1
Patel, A.B.2
Kumari, P.3
Chikhalia, K.H.4
-
8
-
-
84887495816
-
Design, synthesis, antimicrobial activity and anti-HIV activity evaluation of novel hybrid quinazoline-triazine derivatives
-
Early Online, 2013, Accepted Manuscript, DOI: 10. 3109/14756366. 2012. 755622
-
Modh, R. P.; De Clercq, E.; Pannecouque, C.; Chikhalia, K. H. Design, synthesis, antimicrobial activity and anti-HIV activity evaluation of novel hybrid quinazoline-triazine derivatives. J. Enzyme Inhib. Med. Chem. Early Online, 2013, Accepted Manuscript, DOI: 10. 3109/14756366. 2012. 755622.
-
J. Enzyme Inhib. Med. Chem
-
-
Modh, R.P.1
De Clercq, E.2
Pannecouque, C.3
Chikhalia, K.H.4
-
9
-
-
84866743102
-
Synthesis and biological evaluation of novel piperazine derivatives of flavone as potent anti-inflammatory and antimicrobial agent
-
Hatnapure, G. D.; Keche, A. P.; Rodge, A. H.; Birajdar, S. S.; Tale, R. H.; Kamble, V. M. Synthesis and biological evaluation of novel piperazine derivatives of flavone as potent anti-inflammatory and antimicrobial agent. Bioorg. Med. Chem. Lett. 2012, 22, 6385-6390.
-
(2012)
Bioorg. Med. Chem. Lett
, vol.22
, pp. 6385-6390
-
-
Hatnapure, G.D.1
Keche, A.P.2
Rodge, A.H.3
Birajdar, S.S.4
Tale, R.H.5
Kamble, V.M.6
-
10
-
-
84867008865
-
Effects of Varied Substituents on the Antibacterial Activity of Triazolylmethyl Oxazolidinones
-
Phillips, O. A.; Udo, E. E.; Abdel-Hamid, M. E.; Varghese, R. Effects of Varied Substituents on the Antibacterial Activity of Triazolylmethyl Oxazolidinones. Arch. Pharm. Chem. Life Sci. 2012, 345, 790-803.
-
(2012)
Arch. Pharm. Chem. Life Sci
, vol.345
, pp. 790-803
-
-
Phillips, O.A.1
Udo, E.E.2
Abdel-Hamid, M.E.3
Varghese, R.4
-
11
-
-
79951545568
-
Synthesis and in-vitro antibacterial activity of N-alkyl and N-aryl piperazine derivatives
-
Singh, K. K.; Joshi, S. C.; Mathela, S. C. Synthesis and in-vitro antibacterial activity of N-alkyl and N-aryl piperazine derivatives. Ind. J. Chem. 2011, 50B, 196-200.
-
(2011)
Ind. J. Chem
, vol.50 B
, pp. 196-200
-
-
Singh, K.K.1
Joshi, S.C.2
Mathela, S.C.3
-
12
-
-
48549105219
-
Synthesis and antimicrobial studies of novel 1-benzhydryl-piperazine sulfonamide and carboxamide derivatives
-
AnandaKumar, C. S.; Vinaya, K.; Chandra, N. S.; Thimmegowda, N. R.; Benaka, S. B.; Sadashiva, C. T.; Rangappa. K. S. Synthesis and antimicrobial studies of novel 1-benzhydryl-piperazine sulfonamide and carboxamide derivatives. J. Enzyme Inhib. Med. Chem. 2008, 23, 462-469.
-
(2008)
J. Enzyme Inhib. Med. Chem
, vol.23
, pp. 462-469
-
-
AnandaKumar, C.S.1
Vinaya, K.2
Chandra, N.S.3
Thimmegowda, N.R.4
Benaka, S.B.5
Sadashiva, C.T.6
Rangappa, K.S.7
-
13
-
-
1842787547
-
Optically active antifungal azoles: Synthesis and antifungal activity of (2R, 3S)-2-(2, 4-difluorophenyl)-3-(5-[2-[4-aryl-piperazin-1-yl]-ethyl]-tetrazol-2-yl/1-yl)-1-[1, 2, 4]-triazol-1-ylbutan-2-ol
-
Upadhayaya, R. S.; Sinha, N.; Jain, S.; Kishore, N.; Chandra, R.; Arora, S. K. Optically active antifungal azoles: synthesis and antifungal activity of (2R, 3S)-2-(2, 4-difluorophenyl)-3-(5-[2-[4-aryl-piperazin-1-yl]-ethyl]-tetrazol-2-yl/1-yl)-1-[1, 2, 4]-triazol-1-ylbutan-2-ol. Bioorg. Med. Chem. 2004, 12, 2225-2238.
-
(2004)
Bioorg. Med. Chem
, vol.12
, pp. 2225-2238
-
-
Upadhayaya, R.S.1
Sinha, N.2
Jain, S.3
Kishore, N.4
Chandra, R.5
Arora, S.K.6
-
14
-
-
3242703332
-
Synthesis of novel substituted tetrazoles having antifungal activity
-
Upadhayaya, Sinha, N.; R. S.; Jain, S.; Kishore, N.; Chandra, R.; Arora, S. K. Synthesis of novel substituted tetrazoles having antifungal activity. Eur. J. Med. Chem. 2004, 39, 579-592.
-
(2004)
Eur. J. Med. Chem
, vol.39
, pp. 579-592
-
-
Upadhayaya, R.S.1
Sinha, N.2
Jain, S.3
Kishore, N.4
Chandra, R.5
Arora, S.K.6
-
15
-
-
78649325628
-
Synthesis andin vitro antimicrobial evaluation of novel fluoroquinolone derivatives
-
Srinivasan, S.; Shafreen, R. M. B.; Nithyanand, P.; Manisankar, P.; Pandian. S. K. Synthesis andin vitro antimicrobial evaluation of novel fluoroquinolone derivatives. Eur. J. Med. Chem. 2010, 45, 6101-6105.
-
(2010)
Eur. J. Med. Chem
, vol.45
, pp. 6101-6105
-
-
Srinivasan, S.1
Shafreen, R.M.B.2
Nithyanand, P.3
Manisankar, P.4
Pandian, S.K.5
-
16
-
-
80755128442
-
Ynthesis and antibacterial activity of some novel N2-hydroxymethyl and N2-aminomethyl derivatives of 4-aryl-5-(3-chlorophenyl)-2, 4-dihydro-3H-1, 2, 4-triazole-3-thione
-
Plech, T.; Wujec, M.; Kapron, B.; Kosikowska, U.; Malm, A. ynthesis and antibacterial activity of some novel N2-hydroxymethyl and N2-aminomethyl derivatives of 4-aryl-5-(3-chlorophenyl)-2, 4-dihydro-3H-1, 2, 4-triazole-3-thione. Heteroatom Chem. 2011, 22, 737-743.
-
(2011)
Heteroatom Chem
, vol.22
, pp. 737-743
-
-
Plech, T.1
Wujec, M.2
Kapron, B.3
Kosikowska, U.4
Malm, A.5
-
17
-
-
32044472790
-
Synthesis and antimicrobial activity of N-alkyl and N-aryl piperazine derivatives
-
Chaudhary, P.; Kumar, R.; Verma, A. K.; Singh, D.; Yadav, V.; Chhillar, A. K.; Sharma, G. L.; Chandra, R. Synthesis and antimicrobial activity of N-alkyl and N-aryl piperazine derivatives. Bioorg. Med. Chem. 2006, 15, 1819-1826.
-
(2006)
Bioorg. Med. Chem
, vol.15
, pp. 1819-1826
-
-
Chaudhary, P.1
Kumar, R.2
Verma, A.K.3
Singh, D.4
Yadav, V.5
Chhillar, A.K.6
Sharma, G.L.7
Chandra, R.8
-
18
-
-
0037534121
-
Structural features of piperazinyl-linked ciprofloxacin dimers required for activity against drug-resistant strains of Staphylococcus aureus
-
Kerns, R. J.; Rybak, M. J.; Kaatz, G. W.; Vaka, F.; Cha, R.; Grucz, R. G.; Diwadkard, V. U. Structural features of piperazinyl-linked ciprofloxacin dimers required for activity against drug-resistant strains of Staphylococcus aureus. Bioorg. Med. Chem. Lett. 2003, 13, 2109-2112.
-
(2003)
Bioorg. Med. Chem. Lett
, vol.13
, pp. 2109-2112
-
-
Kerns, R.J.1
Rybak, M.J.2
Kaatz, G.W.3
Vaka, F.4
Cha, R.5
Grucz, R.G.6
Diwadkard, V.U.7
-
19
-
-
77957825924
-
Synthesis and biological evaluation of some 1, 3, 4-oxadiazole derivatives
-
Manjunatha, K.; Poojary, B.; Lobo, P. L.; Fernandes, J.; Kumari, N. S. Synthesis and biological evaluation of some 1, 3, 4-oxadiazole derivatives. Eur. J. Med. Chem. 2010, 45, 5225-5233.
-
(2010)
Eur. J. Med. Chem
, vol.45
, pp. 5225-5233
-
-
Manjunatha, K.1
Poojary, B.2
Lobo, P.L.3
Fernandes, J.4
Kumari, N.S.5
-
20
-
-
84857045387
-
Synthesis and antibacterial activity of betulonic acid amides with piperazine derivatives
-
Chue, K. T.; Chang, M. S.; Ten, L. N. Synthesis and antibacterial activity of betulonic acid amides with piperazine derivatives. Chem. Nat. Compd. 2011, 47, 759-763.
-
(2011)
Chem. Nat. Compd
, vol.47
, pp. 759-763
-
-
Chue, K.T.1
Chang, M.S.2
Ten, L.N.3
-
21
-
-
67349229301
-
Synthesis and antibacterial activity of novel 5-(4-methyl-1H-1, 2, 3-triazole) methyl oxazolidinones
-
Phillips, O. A.; Udo, E. E.; Abdel-Hamid, M. E.; Varghese, R. Synthesis and antibacterial activity of novel 5-(4-methyl-1H-1, 2, 3-triazole) methyl oxazolidinones. Eur. J. Med. Chem. 2009, 44, 3217-3227.
-
(2009)
Eur. J. Med. Chem
, vol.44
, pp. 3217-3227
-
-
Phillips, O.A.1
Udo, E.E.2
Abdel-Hamid, M.E.3
Varghese, R.4
-
22
-
-
84870157233
-
-
J. Chem. Accepted Manuscript, doi: 10. 1155/2013/462594
-
Patil, B. S.; Krishnamurthy, G.; Shashikumar, N. D.; Lokesh, M. R.; Naik, H. S. B. Synthesis and antimicrobial activity of some [1, 2, 4]-triazole derivatives. J. Chem. 2013, Accepted Manuscript, doi: 10. 1155/2013/462594.
-
(2013)
Synthesis and antimicrobial activity of some [1, 2, 4]-triazole derivatives
-
-
Patil, B.S.1
Krishnamurthy, G.2
Shashikumar, N.D.3
Lokesh, M.R.4
Naik, H.S.B.5
-
23
-
-
33747194780
-
Synthesis and in vitroantimicrobial studies of medicinally important novel N-alkyl and N-sulfonyl derivatives of 1-[bis (4-fluorophenyl)-methyl] piperazine
-
Narendra, J. N.; Chandra, S.; Sadashiva, C. T.; Kavitha, C. V.; Rangappa, K. S. Synthesis and in vitroantimicrobial studies of medicinally important novel N-alkyl and N-sulfonyl derivatives of 1-[bis (4-fluorophenyl)-methyl] piperazine. Bioorg. Med. Chem. 2006, 14, 6621-6627.
-
(2006)
Bioorg. Med. Chem
, vol.14
, pp. 6621-6627
-
-
Narendra, J.N.1
Chandra, S.2
Sadashiva, C.T.3
Kavitha, C.V.4
Rangappa, K.S.5
-
24
-
-
84879688615
-
Synthesis antimicrobial and anticancer activity of N'-arylmethylidene-piperazine-1-carbothiohydrazide
-
Kulandaivelu, U.; Shireesha, B.; Mahesh, C.; Vidyasagar, J. V.; Rao, T. R.; Jayaveera, K. N.; Saiko, P.; Graser, G.; Szekeres, T.; Jayaprakash, V. Synthesis antimicrobial and anticancer activity of N'-arylmethylidene-piperazine-1-carbothiohydrazide. Med. Chem. Res. 2013, 22, 2802-2808.
-
(2013)
Med. Chem. Res
, vol.22
, pp. 2802-2808
-
-
Kulandaivelu, U.1
Shireesha, B.2
Mahesh, C.3
Vidyasagar, J.V.4
Rao, T.R.5
Jayaveera, K.N.6
Saiko, P.7
Graser, G.8
Szekeres, T.9
Jayaprakash, V.10
-
25
-
-
77953404992
-
Synthesis of novel piperazine and morpholine linked substituted pyrimidine derivatives as antimicrobial agents
-
Basavaraja, H. S.; Jayadevaiah, K. V.; Hussain, M. M.; VijayKumar, M. M.; Basavaraj, P. Synthesis of novel piperazine and morpholine linked substituted pyrimidine derivatives as antimicrobial agents. J. Pharm. Sci. Res. 2010, 2, 5-12.
-
(2010)
J. Pharm. Sci. Res
, vol.2
, pp. 5-12
-
-
Basavaraja, H.S.1
Jayadevaiah, K.V.2
Hussain, M.M.3
VijayKumar, M.M.4
Basavaraj, P.5
-
26
-
-
84873992855
-
Synthesis and antimicrobial screening of 4-thiazolidinone and 2-azetidinone derivatives of piperazine
-
Shingade, S. G.; Bari, S. B. Synthesis and antimicrobial screening of 4-thiazolidinone and 2-azetidinone derivatives of piperazine. Med. Chem. Res. 2013, 22, 699-706.
-
(2013)
Med. Chem. Res
, vol.22
, pp. 699-706
-
-
Shingade, S.G.1
Bari, S.B.2
-
27
-
-
84870512293
-
-
WHO
-
WHO, Global tuberculosis report 2012, http://apps. who. int/iris/bitstream/10665/75938/1/9789241564502_eng. pdf.
-
Global tuberculosis report 2012
-
-
-
28
-
-
84862529315
-
Antimicrobial, anti-TB, anticancer and anti-HIV evaluation of newer s-triazine based heterocycles
-
Patel, R. V.; Kumari, P.; Rajani, D. P.; Pannecouque, C.; De Clercq, E.; Chikhalia, K. H. Antimicrobial, anti-TB, anticancer and anti-HIV evaluation of newer s-triazine based heterocycles. Fut. Med. Chem. 2012, 4, 1053-1065.
-
(2012)
Fut. Med. Chem
, vol.4
, pp. 1053-1065
-
-
Patel, R.V.1
Kumari, P.2
Rajani, D.P.3
Pannecouque, C.4
De Clercq, E.5
Chikhalia, K.H.6
-
29
-
-
84860363364
-
A new class of 2-(4-cyanophenyl amino)-4-(6-bromo-4-quinolinyloxy)-6-piperazinyl(piperidinyl)-1, 3, 5-triazine analogues with antimicrobial/antimycobacterial activity
-
Patel, R. V.; Kumari, P.; Rajani, D. P.; Chikhalia, K. H. A new class of 2-(4-cyanophenyl amino)-4-(6-bromo-4-quinolinyloxy)-6-piperazinyl(piperidinyl)-1, 3, 5-triazine analogues with antimicrobial/antimycobacterial activity. J. Enzyme Inhib. Med. Chem. 2012, 27, 370-379.
-
(2012)
J. Enzyme Inhib. Med. Chem
, vol.27
, pp. 370-379
-
-
Patel, R.V.1
Kumari, P.2
Rajani, D.P.3
Chikhalia, K.H.4
-
30
-
-
84255189563
-
Synthesis and Antimycobacterial Activity of Various 1-(8-quinolinyloxy)-3-piperazinyl(piperidinyl)-5-(4-cyano-3-trifluoromethylphenyl amino)-s-triazines
-
Patel, R. V.; Kumari, P.; Rajani, D. P.; Chikhalia, K. H. Synthesis and Antimycobacterial Activity of Various 1-(8-quinolinyloxy)-3-piperazinyl(piperidinyl)-5-(4-cyano-3-trifluoromethylphenyl amino)-s-triazines. Acta Chim. Slov. 2011, 58, 802-810.
-
(2011)
Acta Chim. Slov
, vol.58
, pp. 802-810
-
-
Patel, R.V.1
Kumari, P.2
Rajani, D.P.3
Chikhalia, K.H.4
-
31
-
-
80052941882
-
Synthesis and studies of novel 2-(4-cyano-3-trifluoromethylphenyl amino)-4-(quinoline-4-yloxy)-6-(piperazinyl/piperidinyl)-s-triazines as potential antimicrobial, antimycobacterial and anticancer agents
-
Patel, R. V.; Kumari, P.; Rajani, D. P.; Chikhalia, K. H. Synthesis and studies of novel 2-(4-cyano-3-trifluoromethylphenyl amino)-4-(quinoline-4-yloxy)-6-(piperazinyl/piperidinyl)-s-triazines as potential antimicrobial, antimycobacterial and anticancer agents. Eur. J. Med. Chem. 2011, 46, 4354-4365.
-
(2011)
Eur. J. Med. Chem
, vol.46
, pp. 4354-4365
-
-
Patel, R.V.1
Kumari, P.2
Rajani, D.P.3
Chikhalia, K.H.4
-
32
-
-
78650512116
-
Novel isatinyl thiosemicarbazones derivatives as potential molecule to combat HIV-TB co-infection
-
Banerjee, D.; Yogeeswari, P.; Bhat, P.; Thomas, A.; Srividya, M.; Sriram. D. Novel isatinyl thiosemicarbazones derivatives as potential molecule to combat HIV-TB co-infection. Eur. J. Med. Chem. 2011, 46, 106-121.
-
(2011)
Eur. J. Med. Chem
, vol.46
, pp. 106-121
-
-
Banerjee, D.1
Yogeeswari, P.2
Bhat, P.3
Thomas, A.4
Srividya, M.5
Sriram, D.6
-
33
-
-
33644810533
-
Bioorg. Synthesis of pyrazinamide Mannich bases and its antitubercular properties
-
Sriram, D.; Yogeeswari, P.; Reddy, S. P. Bioorg. Synthesis of pyrazinamide Mannich bases and its antitubercular properties. Bioorg. Med. Chem. Lett. 2006, 16, 2113-2116.
-
(2006)
Bioorg. Med. Chem. Lett
, vol.16
, pp. 2113-2116
-
-
Sriram, D.1
Yogeeswari, P.2
Reddy, S.P.3
-
34
-
-
24344459482
-
Synthesis and in vitro and in vivo antimycobacterial activity of isonicotinoyl hydrazones
-
Sriram, D.; Yogeeswari, P.; Madhu, K. Synthesis and in vitro and in vivo antimycobacterial activity of isonicotinoyl hydrazones. Bioorg. Med. Chem. Lett. 2005, 15, 4502-4505.
-
(2005)
Bioorg. Med. Chem. Lett
, vol.15
, pp. 4502-4505
-
-
Sriram, D.1
Yogeeswari, P.2
Madhu, K.3
-
35
-
-
29744457268
-
Synthesis and evaluation of cyclic secondary amine substituted phenyl and benzyl nitrofuranyl amides as novel antituberculosis agents
-
Tangallapally, R. P.; Yendapally, R.; Lee, R. E.; Lenaerts, A. J. M.; Lee, R. E. Synthesis and evaluation of cyclic secondary amine substituted phenyl and benzyl nitrofuranyl amides as novel antituberculosis agents. J. Med. Chem. 2005, 48, 8261-8269.
-
(2005)
J. Med. Chem
, vol.48
, pp. 8261-8269
-
-
Tangallapally, R.P.1
Yendapally, R.2
Lee, R.E.3
Lenaerts, A.J.M.4
Lee, R.E.5
-
36
-
-
77949488931
-
Novel quinoline and naphthalene derivatives as potent antimycobacterial agents
-
Upadhayaya, R. S.; Vandavasi, J. K.; Kardile, R. A.; Lahore, S. V.; Dixit, S. S.; Deokar, H. S.; Shinde, P. D.; Sarmah, M. P.; Chattopadhyaya, J. Novel quinoline and naphthalene derivatives as potent antimycobacterial agents. Eur. J. Med. Chem. 2010, 45, 1854-1867.
-
(2010)
Eur. J. Med. Chem
, vol.45
, pp. 1854-1867
-
-
Upadhayaya, R.S.1
Vandavasi, J.K.2
Kardile, R.A.3
Lahore, S.V.4
Dixit, S.S.5
Deokar, H.S.6
Shinde, P.D.7
Sarmah, M.P.8
Chattopadhyaya, J.9
-
37
-
-
70349774229
-
Pentacyclo-undecane derived cyclic tetra-amines: Synthesis and evaluation as potent anti-tuberculosis agents
-
Onajole, O. K.; Govender, K.; Govender, P.; van Helden, P. D.; Kruger, H. G.; Maguire, G. E. M.; Muthusamy, K.; Pillay, M.; Wiid, I.; Govender, T. Pentacyclo-undecane derived cyclic tetra-amines: Synthesis and evaluation as potent anti-tuberculosis agents. Eur. J. Med. Chem. 2009, 44, 4297-4305.
-
(2009)
Eur. J. Med. Chem
, vol.44
, pp. 4297-4305
-
-
Onajole, O.K.1
Govender, K.2
Govender, P.3
van Helden, P.D.4
Kruger, H.G.5
Maguire, G.E.M.6
Muthusamy, K.7
Pillay, M.8
Wiid, I.9
Govender, T.10
-
38
-
-
19444378522
-
Synthesis and antimycobacterial evaluation of certain fluoroquinolone derivatives
-
Zhao, Y. L.; Chen, Y. L.; Sheu, J. Y.; Chen, I. L.; Wang, T. C.; Tzeng, C. C. Synthesis and antimycobacterial evaluation of certain fluoroquinolone derivatives. Bioorg. Med. Chem. 2005, 13, 3921-3926.
-
(2005)
Bioorg. Med. Chem
, vol.13
, pp. 3921-3926
-
-
Zhao, Y.L.1
Chen, Y.L.2
Sheu, J.Y.3
Chen, I.L.4
Wang, T.C.5
Tzeng, C.C.6
-
39
-
-
79952437599
-
Synthesis and in vitro antimycobacterial activities of novel 6-substituted-3(2H)-pyridazinone-2-acetyl-2-(substituted/nonsubstituted acetophenone) hydrazone
-
Utku, S.; Gokce, M.; Aslan, G.; Bayram, G.; Ulger, M.; Emekdas, G.; Sahin, M. F. Synthesis and in vitro antimycobacterial activities of novel 6-substituted-3(2H)-pyridazinone-2-acetyl-2-(substituted/nonsubstituted acetophenone) hydrazone. Turk. J. Chem. 2011, 35, 331-339.
-
(2011)
Turk. J. Chem
, vol.35
, pp. 331-339
-
-
Utku, S.1
Gokce, M.2
Aslan, G.3
Bayram, G.4
Ulger, M.5
Emekdas, G.6
Sahin, M.F.7
-
40
-
-
82955178707
-
Synthesis and in-vitro antimycobacterial activity of fluoroquinolone derivatives containing a coumarin moiety
-
Guo, Q.; Liu, M. L.; Feng, L. S.; Lv, K.; Guan, Y.; Guo, H. Y.; Xiao, C. L. Synthesis and in-vitro antimycobacterial activity of fluoroquinolone derivatives containing a coumarin moiety. Arch. Pharm. Chem. Life Sci. 2011, 344, 802-809.
-
(2011)
Arch. Pharm. Chem. Life Sci
, vol.344
, pp. 802-809
-
-
Guo, Q.1
Liu, M.L.2
Feng, L.S.3
Lv, K.4
Guan, Y.5
Guo, H.Y.6
Xiao, C.L.7
-
41
-
-
79955643105
-
New quinolin-4-yl-1, 2, 3-triazoles carrying amides, sulphonamides and amidopiperazines as potential antitubercular agents
-
Thomas, K. D.; Adhikari, A. V.; Chowdhury, I. H.; Sumesh, E.; Pal, N. K. New quinolin-4-yl-1, 2, 3-triazoles carrying amides, sulphonamides and amidopiperazines as potential antitubercular agents. Eur. J. Med. Chem. 2011, 46, 2503-2512.
-
(2011)
Eur. J. Med. Chem
, vol.46
, pp. 2503-2512
-
-
Thomas, K.D.1
Adhikari, A.V.2
Chowdhury, I.H.3
Sumesh, E.4
Pal, N.K.5
-
42
-
-
77951136077
-
Progress of bis(heteroaryl)piperazines (BHAPs) as nonnucleoside reverse transcriptase inhibitors (NNRTIs) against human immunodeficiency virus type 1 (HIV-1)
-
Xu, H. Progress of bis(heteroaryl)piperazines (BHAPs) as nonnucleoside reverse transcriptase inhibitors (NNRTIs) against human immunodeficiency virus type 1 (HIV-1). Mini Rev. Med. Chem. 2010, 10, 62-72.
-
(2010)
Mini Rev. Med. Chem
, vol.10
, pp. 62-72
-
-
Xu, H.1
-
43
-
-
24344485653
-
Synthesis and evaluation of anti-HIV activity of isatin beta-thiosemicarbazone derivatives
-
Bal, T. R.; Anand, B.; Yogeeswari, P.; Sriram. D. Synthesis and evaluation of anti-HIV activity of isatin beta-thiosemicarbazone derivatives. Bioorg. Med. Chem. Lett. 2005, 15, 4451-4455.
-
(2005)
Bioorg. Med. Chem. Lett
, vol.15
, pp. 4451-4455
-
-
Bal, T.R.1
Anand, B.2
Yogeeswari, P.3
Sriram, D.4
-
44
-
-
68349141359
-
Inhibitors of HIV-1 attachment. Part 4: A study of the effect of piperazine substitution patterns on antiviral potency in the context of indole-based derivatives
-
Wang, T.; Kadow, J. F.; Zhang, Z.; Yin, Z.; Gao, Q.; Wu, D.; Parker, D. D.; Yang, Z.; Zadjura, L.; Robinson, B. A.; Gong, Y. F.; Spicer, T. P.; Blair, W. S.; Shi, P. Y.; Yamanaka, G.; Lin, P. F.; Meanwell, N. A. Inhibitors of HIV-1 attachment. Part 4: A study of the effect of piperazine substitution patterns on antiviral potency in the context of indole-based derivatives. Bioorg. Med. Chem. Lett. 2009, 19, 5140-5145.
-
(2009)
Bioorg. Med. Chem. Lett
, vol.19
, pp. 5140-5145
-
-
Wang, T.1
Kadow, J.F.2
Zhang, Z.3
Yin, Z.4
Gao, Q.5
Wu, D.6
Parker, D.D.7
Yang, Z.8
Zadjura, L.9
Robinson, B.A.10
Gong, Y.F.11
Spicer, T.P.12
Blair, W.S.13
Shi, P.Y.14
Yamanaka, G.15
Lin, P.F.16
Meanwell, N.A.17
-
45
-
-
0032535256
-
Potent piperazine hydroxyethylamine HIV protease inhibitors containing novel P3 ligands
-
Chert, X.; Kempf, D. J.; Sham, H. L.; Green, B. E.; Molla, A.; Korneyeva, M.; Vasavanonda, S.; Wideburg, N. E.; Saldivar, A.; Marsh, K. C.; McDonald, E.; Norbeck, D. W. Potent piperazine hydroxyethylamine HIV protease inhibitors containing novel P3 ligands. Bioorg. Med. Chem. Lett. 1998, 8, 3531-3536.
-
(1998)
Bioorg. Med. Chem. Lett
, vol.8
, pp. 3531-3536
-
-
Chert, X.1
Kempf, D.J.2
Sham, H.L.3
Green, B.E.4
Molla, A.5
Korneyeva, M.6
Vasavanonda, S.7
Wideburg, N.E.8
Saldivar, A.9
Marsh, K.C.10
McDonald, E.11
Norbeck, D.W.12
-
46
-
-
6044239447
-
Structure modifications of 6-aminoquinolones with potent anti-HIV activity
-
Tabarrini, O.; Stevens, M.; Cecchetti, V.; Sabatini, S.; DellUomo, M.; Manfroni, G.; Palumbo, M.; Pannecouque, C.; De Clercq, E.; Fravolini, A. Structure modifications of 6-aminoquinolones with potent anti-HIV activity. J. Med. Chem. 2004, 47, 5567-5578.
-
(2004)
J. Med. Chem
, vol.47
, pp. 5567-5578
-
-
Tabarrini, O.1
Stevens, M.2
Cecchetti, V.3
Sabatini, S.4
DellUomo, M.5
Manfroni, G.6
Palumbo, M.7
Pannecouque, C.8
De Clercq, E.9
Fravolini, A.10
-
47
-
-
77249177585
-
A 1, 8-naphthyridone derivative targets the HIV-1 Tat-mediated transcription and potently inhibits the HIV-1 replication
-
Massari, S.; Daelemans, D.; Barreca, M. L.; Knezevich, A.; Sabatini, S.; Cecchetti, V.; Marcello, A.; Pannecouque, C.; Tabarrini, O. A 1, 8-naphthyridone derivative targets the HIV-1 Tat-mediated transcription and potently inhibits the HIV-1 replication. J. Med. Chem. 2010, 53, 641-648.
-
(2010)
J. Med. Chem
, vol.53
, pp. 641-648
-
-
Massari, S.1
Daelemans, D.2
Barreca, M.L.3
Knezevich, A.4
Sabatini, S.5
Cecchetti, V.6
Marcello, A.7
Pannecouque, C.8
Tabarrini, O.9
-
48
-
-
84871027952
-
Part 10. The discovery and structure-activity relationships of 4-azaindole cores
-
Inhibitors of HIV-1 attachment
-
Wang, T.; Yang, Z.; Zhang, Z.; Gong, Y. F.; Riccardi, K. A.; Lin, P. F.; Parker, D. D.; Rahematpura, S.; Mathew, M.; Zheng, M.; Meanwell, N. A.; Kadow, J. F.; Bender, J. A.; Inhibitors of HIV-1 attachment. Part 10. The discovery and structure-activity relationships of 4-azaindole cores. Bioorg. Med. Chem. Lett. 2013, 23, 213-217.
-
(2013)
Bioorg. Med. Chem. Lett
, vol.23
, pp. 213-217
-
-
Wang, T.1
Yang, Z.2
Zhang, Z.3
Gong, Y.F.4
Riccardi, K.A.5
Lin, P.F.6
Parker, D.D.7
Rahematpura, S.8
Mathew, M.9
Zheng, M.10
Meanwell, N.A.11
Kadow, J.F.12
Bender, J.A.13
-
49
-
-
0033231154
-
Synthesis and anti-HIV activity of arylpiperazinyl fluoroquinolones: A new class of anti-HIV agents
-
Hagihara, M.; Kashiwase, H.; Katsube, T.; Kimura, T.; Komai, T.; Momota, K.; Ohmine, T.; Nishigaki, T.; Kimura, S.; Shimad, K. Synthesis and anti-HIV activity of arylpiperazinyl fluoroquinolones: a new class of anti-HIV agents. Bioorg. Med. Chem. Lett. 1999, 9, 3063-3068.
-
(1999)
Bioorg. Med. Chem. Lett
, vol.9
, pp. 3063-3068
-
-
Hagihara, M.1
Kashiwase, H.2
Katsube, T.3
Kimura, T.4
Komai, T.5
Momota, K.6
Ohmine, T.7
Nishigaki, T.8
Kimura, S.9
Shimad, K.10
-
50
-
-
84655163250
-
Inhibition of noroviruses by piperazine derivatives
-
Dou, D.; He, G.; Mandadapu, S. R.; Aravapalli, S.; Kim, Y.; Chang, K.; Groutas, W. C. Inhibition of noroviruses by piperazine derivatives. Bioorg. Med. Chem. Lett. 2012, 22, 377-379.
-
(2012)
Bioorg. Med. Chem. Lett
, vol.22
, pp. 377-379
-
-
Dou, D.1
He, G.2
Mandadapu, S.R.3
Aravapalli, S.4
Kim, Y.5
Chang, K.6
Groutas, W.C.7
-
51
-
-
78751650641
-
Pharmacophore-based design, synthesis, and biological evaluation of novel chloro-pyridazine piperazines as human rhinovirus (HRV-3) inhibitors
-
Wang, H.; Xiao, J.; Gao, D.; Zhang, X.; Yan, H.; Gong, Z.; Suna, T.; Li, S. Pharmacophore-based design, synthesis, and biological evaluation of novel chloro-pyridazine piperazines as human rhinovirus (HRV-3) inhibitors. Bioorg. Med. Chem. Lett. 2011, 21, 1057-1059.
-
(2011)
Bioorg. Med. Chem. Lett
, vol.21
, pp. 1057-1059
-
-
Wang, H.1
Xiao, J.2
Gao, D.3
Zhang, X.4
Yan, H.5
Gong, Z.6
Suna, T.7
Li, S.8
-
52
-
-
1942438497
-
Design, synthesis, and structure-activity relationships of pyrazolo[3, 4-d]pyrimidines: A novel class of potent enterovirus inhibitors
-
Chern, J. H.; Shia, K. S.; Hsu, T. A.; Tai, C. L.; Lee, C. C.; Lee, Y. C.; Chang, C. S.; Tseng, S. N.; Shih, S. R. Design, synthesis, and structure-activity relationships of pyrazolo[3, 4-d]pyrimidines: a novel class of potent enterovirus inhibitors. Bioorg. Med. Chem. Lett. 2004, 14, 2519-2525.
-
(2004)
Bioorg. Med. Chem. Lett
, vol.14
, pp. 2519-2525
-
-
Chern, J.H.1
Shia, K.S.2
Hsu, T.A.3
Tai, C.L.4
Lee, C.C.5
Lee, Y.C.6
Chang, C.S.7
Tseng, S.N.8
Shih, S.R.9
-
53
-
-
84863232815
-
Design, synthesis, and in vitro biological evaluation of 1H-1, 2, 3-triazole-4-carboxamide derivatives as new anti-influenza A agents targeting virus nucleoprotein
-
Cheng, H.; Wan, J.; Lin, M. I.; Liu, Y.; Lu, X.; Liu, J.; Xu, Y.; Chen, J.; Tu, Z.; Cheng, Y. S. E.; Ding, K. Design, synthesis, and in vitro biological evaluation of 1H-1, 2, 3-triazole-4-carboxamide derivatives as new anti-influenza A agents targeting virus nucleoprotein. J. Med. Chem. 2012, 55, 2144-2153.
-
(2012)
J. Med. Chem
, vol.55
, pp. 2144-2153
-
-
Cheng, H.1
Wan, J.2
Lin, M.I.3
Liu, Y.4
Lu, X.5
Liu, J.6
Xu, Y.7
Chen, J.8
Tu, Z.9
Cheng, Y.S.E.10
Ding, K.11
-
54
-
-
78449260687
-
Synthesis and anticancer activity of new 1-[(5 or 6-substituted 2-alkoxyquinoxalin-3-yl)aminocarbonyl]-4-(hetero)arylpiperazine derivatives
-
Lee, Y. B.; Gong, Y. D.; Yoon, H.; Ahn, C. H.; Jeon, M. K.; Kong, J. Y. Synthesis and anticancer activity of new 1-[(5 or 6-substituted 2-alkoxyquinoxalin-3-yl)aminocarbonyl]-4-(hetero)arylpiperazine derivatives. Bioorg. Med. Chem. 2010, 18, 7966-7974.
-
(2010)
Bioorg. Med. Chem
, vol.18
, pp. 7966-7974
-
-
Lee, Y.B.1
Gong, Y.D.2
Yoon, H.3
Ahn, C.H.4
Jeon, M.K.5
Kong, J.Y.6
-
55
-
-
77954349751
-
Synthesis and structureactivity relationship study of 8-hydroxyquinoline-derived Mannich bases as anticancer agents
-
Shawa, A. Y.; Chang, C. Y.; Hsu, M. Y.; Lu, P. J.; Yang, C. N.; Chen, H. L.; Lo, C. W.; Shia, C. W.; Chern, M. K. Synthesis and structureactivity relationship study of 8-hydroxyquinoline-derived Mannich bases as anticancer agents. Eur. J. Med. Chem. 2010, 45, 2860-2867.
-
(2010)
Eur. J. Med. Chem
, vol.45
, pp. 2860-2867
-
-
Shawa, A.Y.1
Chang, C.Y.2
Hsu, M.Y.3
Lu, P.J.4
Yang, C.N.5
Chen, H.L.6
Lo, C.W.7
Shia, C.W.8
Chern, M.K.9
-
56
-
-
84863885254
-
Design, synthesis, and biological evaluation of indole-based 1, 4-disubstituted piperazines as cytotoxic agents
-
Akkoc, M. K.; Yuksel, M. Y.; Durmaz, I.; Atalay, R. C. Design, synthesis, and biological evaluation of indole-based 1, 4-disubstituted piperazines as cytotoxic agents Turk. J. Chem. 2012, 36, 515-525.
-
(2012)
Turk. J. Chem
, vol.36
, pp. 515-525
-
-
Akkoc, M.K.1
Yuksel, M.Y.2
Durmaz, I.3
Atalay, R.C.4
-
57
-
-
84859806562
-
Synthesis of novel 6-(4-substituted piperazine-1-yl)-9-(-D-ribofuranosyl)purine derivatives, which lead to senescence-induced cell death in liver cancer cells
-
Tuncbilek, M.; Guven, E. B.; Onder, T.; Atalay, R. C. Synthesis of novel 6-(4-substituted piperazine-1-yl)-9-(-D-ribofuranosyl)purine derivatives, which lead to senescence-induced cell death in liver cancer cells. J. Med. Chem. 2012, 55, 3058-3065.
-
(2012)
J. Med. Chem
, vol.55
, pp. 3058-3065
-
-
Tuncbilek, M.1
Guven, E.B.2
Onder, T.3
Atalay, R.C.4
-
58
-
-
65349118307
-
Synthesis and evaluation of piperazine and homopiperazine analogues of JS-K, an anti-cancer lead compound
-
Nandurdikar, R. S.; Maciag, A. E.; Citro, M. L.; Shami, P. J.; Keefer, L. K.; Saavedra, J. E.; Chakrapani, H. Synthesis and evaluation of piperazine and homopiperazine analogues of JS-K, an anti-cancer lead compound. Bioorg. Med. Chem. Lett. 2009, 19, 2760-2762.
-
(2009)
Bioorg. Med. Chem. Lett
, vol.19
, pp. 2760-2762
-
-
Nandurdikar, R.S.1
Maciag, A.E.2
Citro, M.L.3
Shami, P.J.4
Keefer, L.K.5
Saavedra, J.E.6
Chakrapani, H.7
-
59
-
-
84856000764
-
Synthesis of novel 2, 5-dihydrofuran derivatives and evaluation of their anticancer activity
-
Zhang, Y.; Zhong, H.; Wang, T.; Geng, D.; Zhang, M.; Li, K. Synthesis of novel 2, 5-dihydrofuran derivatives and evaluation of their anticancer activity. Eur. J. Med. Chem. 2012, 48, 69-80.
-
(2012)
Eur. J. Med. Chem
, vol.48
, pp. 69-80
-
-
Zhang, Y.1
Zhong, H.2
Wang, T.3
Geng, D.4
Zhang, M.5
Li, K.6
-
60
-
-
84860466359
-
Synthesis, α, β-receptors binding affinity and antiproliferative action of new C1-substituted adamantanes
-
Riganas, S.; Papanastasiou, I.; Foscolos, G. B.; Tsotinis, A.; Bourguignon, J. J.; Serin, G.; Mirjolet, J. F.; Dimas, K.; Kourafalos, V. N.; Eleutheriades, A.; Moutsos, V. I.; Khan, H.; Georgakopoulou, S.; Zaniou, A.; Prassa, M.; Theodoropoulou, M.; Pondiki, S.; Vamvakides, A. Synthesis, α, β-receptors binding affinity and antiproliferative action of new C1-substituted adamantanes. Bioorg. Med. Chem. 2012, 20, 3323-3331.
-
(2012)
Bioorg. Med. Chem
, vol.20
, pp. 3323-3331
-
-
Riganas, S.1
Papanastasiou, I.2
Foscolos, G.B.3
Tsotinis, A.4
Bourguignon, J.J.5
Serin, G.6
Mirjolet, J.F.7
Dimas, K.8
Kourafalos, V.N.9
Eleutheriades, A.10
Moutsos, V.I.11
Khan, H.12
Georgakopoulou, S.13
Zaniou, A.14
Prassa, M.15
Theodoropoulou, M.16
Pondiki, S.17
Vamvakides, A.18
-
61
-
-
84856235620
-
Synthesis, anticancer activity and pharmacokinetic analysis of 1-[(substituted 2-alkoxyquinoxalin-3-yl)aminocarbonyl]-4-(hetero) arylpiperazine derivatives
-
Lee, Y. B.; Gong, Y. D.; Kim, D. J.; Ahn, C. H.; Kong, J. Y.; Kang, N. S. Synthesis, anticancer activity and pharmacokinetic analysis of 1-[(substituted 2-alkoxyquinoxalin-3-yl)aminocarbonyl]-4-(hetero) arylpiperazine derivatives. Bioorg. Med. Chem. 2012, 20, 1303-1309.
-
(2012)
Bioorg. Med. Chem
, vol.20
, pp. 1303-1309
-
-
Lee, Y.B.1
Gong, Y.D.2
Kim, D.J.3
Ahn, C.H.4
Kong, J.Y.5
Kang, N.S.6
-
62
-
-
84879696557
-
Synthesis and screening of 2-(2-(4-substituted piperazine-1-yl)-5-phenylthiazol-4-yl)-3-aryl quinazolinone derivatives as anticancer agents
-
Sharma, R. N.; Ravani, R. Synthesis and screening of 2-(2-(4-substituted piperazine-1-yl)-5-phenylthiazol-4-yl)-3-aryl quinazolinone derivatives as anticancer agents. Med. Chem. Res. 2013, 22, 2788-2794.
-
(2013)
Med. Chem. Res
, vol.22
, pp. 2788-2794
-
-
Sharma, R.N.1
Ravani, R.2
-
63
-
-
62549131192
-
Synthesis and cytotoxicity screening of piperazine-1-carbodithioate derivatives of 2-substituted quinazolin-4(3H)-ones
-
Cao, S. L.; Guo, Y. W.; Wang, X. B.; Zhang, M.; Feng, Y. P.; Jiang, Y. Y.; Wang, Y.; Gao, Q.; Ren, J. Synthesis and cytotoxicity screening of piperazine-1-carbodithioate derivatives of 2-substituted quinazolin-4(3H)-ones. Arch. Pharm. Chem. Life Sci. 2009, 342, 182-189.
-
(2009)
Arch. Pharm. Chem. Life Sci
, vol.342
, pp. 182-189
-
-
Cao, S.L.1
Guo, Y.W.2
Wang, X.B.3
Zhang, M.4
Feng, Y.P.5
Jiang, Y.Y.6
Wang, Y.7
Gao, Q.8
Ren, J.9
-
64
-
-
84859724187
-
Synthesis and cytotoxic evaluation of some new phthalazinylpiperazine derivatives
-
Liu, Y.; Zhang, S.; Li, Y.; Wang, J.; Song, Y.; Gong, P. Synthesis and cytotoxic evaluation of some new phthalazinylpiperazine derivatives. Arch. Pharm. Chem. Life Sci. 2012, 345, 287-293.
-
(2012)
Arch. Pharm. Chem. Life Sci
, vol.345
, pp. 287-293
-
-
Liu, Y.1
Zhang, S.2
Li, Y.3
Wang, J.4
Song, Y.5
Gong, P.6
-
65
-
-
80052929303
-
Synthesis and biological evaluation of derivatives of 4-deoxypodophyllotoxin as antitumor agents
-
Jin, Y.; Liu, J.; Huang, W. T.; Chen, S. W.; Hui, L. Synthesis and biological evaluation of derivatives of 4-deoxypodophyllotoxin as antitumor agents. Eur. J. Med. Chem. 2011, 46, 4056-4061.
-
(2011)
Eur. J. Med. Chem
, vol.46
, pp. 4056-4061
-
-
Jin, Y.1
Liu, J.2
Huang, W.T.3
Chen, S.W.4
Hui, L.5
-
66
-
-
60549097869
-
Synthesis and in vitro antiproliferative activity of novel 1-benzhydrylpiperazine derivatives against human cancer cell lines
-
Ananda, C. S.; Kumar, S. B.; Prasad, B.; Vinaya, K.; Chandrappa, S.; Thimmegowda, N. R.; Sunil Kumar, Y. C.; Swarup, S.; Rangappa, K. S. Synthesis and in vitro antiproliferative activity of novel 1-benzhydrylpiperazine derivatives against human cancer cell lines. Eur. J. Med. Chem. 2009, 44, 1223-1229.
-
(2009)
Eur. J. Med. Chem
, vol.44
, pp. 1223-1229
-
-
Ananda, C.S.1
Kumar, S.B.2
Prasad, B.3
Vinaya, K.4
Chandrappa, S.5
Thimmegowda, N.R.6
Sunil Kumar, Y.C.7
Swarup, S.8
Rangappa, K.S.9
-
67
-
-
84864416960
-
Synthesis and biological activity assays of some new N1-(flavon-7-yl)amidrazone derivatives and related congeners
-
Abu-Aisheh, M. N.; Mustafa, M. S.; El-Abadelah, M. M.; Naffa, R. G.; Ismail, S. I.; Zihlif, M. A.; Taha, M. O.; Mubarak, M. S. Synthesis and biological activity assays of some new N1-(flavon-7-yl)amidrazone derivatives and related congeners. Eur. J. Med. Chem. 2012, 54, 65-74.
-
(2012)
Eur. J. Med. Chem
, vol.54
, pp. 65-74
-
-
Abu-Aisheh, M.N.1
Mustafa, M.S.2
El-Abadelah, M.M.3
Naffa, R.G.4
Ismail, S.I.5
Zihlif, M.A.6
Taha, M.O.7
Mubarak, M.S.8
-
68
-
-
77954315435
-
Design, synthesis and anticancer activity of piperazine hydroxamates and their histone deacetylase (HDAC) inhibitory activity
-
Chetan, B.; Bunha, M.; Jagrat, M.; Sinha, B. N.; Saiko, P.; Graser, G.; Szekeres, T.; Raman, G.; Rajendran, P.; Moorthy, D.; Basu, A.; Jayaprakash, V. Design, synthesis and anticancer activity of piperazine hydroxamates and their histone deacetylase (HDAC) inhibitory activity. Bioorg. Med. Chem. Lett. 2010, 20, 3906-3910.
-
(2010)
Bioorg. Med. Chem. Lett
, vol.20
, pp. 3906-3910
-
-
Chetan, B.1
Bunha, M.2
Jagrat, M.3
Sinha, B.N.4
Saiko, P.5
Graser, G.6
Szekeres, T.7
Raman, G.8
Rajendran, P.9
Moorthy, D.10
Basu, A.11
Jayaprakash, V.12
-
69
-
-
84868242594
-
Synthesis and cytotoxicity of novel ursolic acid derivatives containing an acyl piperazine moiety
-
Liu, M. C.; Yang, S. J.; Jin, L. H.; Hu, D. Y.; Xue, W.; Song, B. A.; Yang, S. Synthesis and cytotoxicity of novel ursolic acid derivatives containing an acyl piperazine moiety. Eur. J. Med. Chem. 2012, 58, 128-135.
-
(2012)
Eur. J. Med. Chem
, vol.58
, pp. 128-135
-
-
Liu, M.C.1
Yang, S.J.2
Jin, L.H.3
Hu, D.Y.4
Xue, W.5
Song, B.A.6
Yang, S.7
-
70
-
-
83655184806
-
QSAR on aryl-piperazine derivatives with activity on malaria
-
Ibezim, E.; Duchowicz, P. R.; Ortiz, E. V.; Castro, E. A. QSAR on aryl-piperazine derivatives with activity on malaria. Chemometr. Intell. Lab. 2012, 110, 81-88.
-
(2012)
Chemometr. Intell. Lab
, vol.110
, pp. 81-88
-
-
Ibezim, E.1
Duchowicz, P.R.2
Ortiz, E.V.3
Castro, E.A.4
-
71
-
-
0141656369
-
Synthesis and antimalarial evaluation of new 1, 4-bis(3-aminopropyl)piperazine derivatives
-
Ryckebusch, A.; Deprez-Poulain, R.; Debreu-Fontaine, M. A.; Vandaele, R.; Mouray, E.; Grellierb, P.; Sergheraerta, C. Synthesis and antimalarial evaluation of new 1, 4-bis(3-aminopropyl)piperazine derivatives. Bioorg. Med. Chem. Lett. 2003, 13, 3783-3787.
-
(2003)
Bioorg. Med. Chem. Lett
, vol.13
, pp. 3783-3787
-
-
Ryckebusch, A.1
Deprez-Poulain, R.2
Debreu-Fontaine, M.A.3
Vandaele, R.4
Mouray, E.5
Grellierb, P.6
Sergheraerta, C.7
-
72
-
-
10644221022
-
Synthesis and antimalarial evaluation of new N1-(7-chloro-4-quinolyl)-1, 4-bis(3-aminopropyl)piperazine derivatives
-
Ryckebusch, A.; Debreu-Fontaine, M. A.; Mouray, E.; Grellierb, P.; Sergheraerta, C.; Melnyk, P. Synthesis and antimalarial evaluation of new N1-(7-chloro-4-quinolyl)-1, 4-bis(3-aminopropyl)piperazine derivatives. Bioorg. Med. Chem. Lett. 2005, 15, 297-302.
-
(2005)
Bioorg. Med. Chem. Lett
, vol.15
, pp. 297-302
-
-
Ryckebusch, A.1
Debreu-Fontaine, M.A.2
Mouray, E.3
Grellierb, P.4
Sergheraerta, C.5
Melnyk, P.6
-
73
-
-
60549100346
-
Synthesis and antimalarial activity of hydroxyethylpiperazine derivatives
-
Cunico, W.; Gomes, C. R. B.; Moreth, M.; Manhanini, D. P.; Figueiredo, I. H.; Penido, C.; Henriques, M. G. M. O.; Varotti, F. P.; Krettli, A. U. Synthesis and antimalarial activity of hydroxyethylpiperazine derivatives. Eur. J. Med. Chem. 2009, 44, 1363-1368.
-
(2009)
Eur. J. Med. Chem
, vol.44
, pp. 1363-1368
-
-
Cunico, W.1
Gomes, C.R.B.2
Moreth, M.3
Manhanini, D.P.4
Figueiredo, I.H.5
Penido, C.6
Henriques, M.G.M.O.7
Varotti, F.P.8
Krettli, A.U.9
-
74
-
-
34547532755
-
Application of multicomponent reactions to antimalarial drug discovery. Part 3: Discovery of aminoxazole 4-aminoquinolines with potent antiplasmodial activity in vitro
-
Musonda, C. C.; Little, S.; Yardley, V.; Chibale. K. Application of multicomponent reactions to antimalarial drug discovery. Part 3: discovery of aminoxazole 4-aminoquinolines with potent antiplasmodial activity in vitro. Bioorg. Med. Chem. Lett. 2007, 17, 4733-4736.
-
(2007)
Bioorg. Med. Chem. Lett
, vol.17
, pp. 4733-4736
-
-
Musonda, C.C.1
Little, S.2
Yardley, V.3
Chibale, K.4
-
75
-
-
33846681593
-
Synthesis and antimalarial evaluation of a series of piperazinyl flavones
-
Auffret, G.; Labaied, M.; Frappier, F.; Rasoanaivo, P.; Grellier, P.; Lewin, G. Synthesis and antimalarial evaluation of a series of piperazinyl flavones. Bioorg. Med. Chem. Lett. 2007, 17, 959-963.
-
(2007)
Bioorg. Med. Chem. Lett
, vol.17
, pp. 959-963
-
-
Auffret, G.1
Labaied, M.2
Frappier, F.3
Rasoanaivo, P.4
Grellier, P.5
Lewin, G.6
-
76
-
-
78149279661
-
Synthesis of new 4-aminoquinolines and quinoline-acridine hybrids as antimalarial agents
-
Kumar, A.; Srivastava, K.; Kumar, S. R.; Puri, S. K.; Chauhan, P. M. S. Synthesis of new 4-aminoquinolines and quinoline-acridine hybrids as antimalarial agents. Bioorg. Med. Chem. Lett. 2010, 20, 7059-7063.
-
(2010)
Bioorg. Med. Chem. Lett
, vol.20
, pp. 7059-7063
-
-
Kumar, A.1
Srivastava, K.2
Kumar, S.R.3
Puri, S.K.4
Chauhan, P.M.S.5
-
77
-
-
56249130079
-
Synthesis and bioevaluation of hybrid 4-aminoquinoline triazines as a new class of antimalarial agents
-
Kumar, A.; Srivastava, K.; Kumar, S. R.; Puri, S. K.; Chauhan, P. M. S. Synthesis and bioevaluation of hybrid 4-aminoquinoline triazines as a new class of antimalarial agents. Bioorg. Med. Chem. 2008, 18, 6530-6533.
-
(2008)
Bioorg. Med. Chem
, vol.18
, pp. 6530-6533
-
-
Kumar, A.1
Srivastava, K.2
Kumar, S.R.3
Puri, S.K.4
Chauhan, P.M.S.5
-
78
-
-
19944399749
-
Antimalarial activity and synthesis of new trisubstituted pyrimidines
-
Agarwal, A.; Srivastava, K.; Puri, S. K.; Chauhan, P. M. S. Antimalarial activity and synthesis of new trisubstituted pyrimidines. Bioorg. Med. Chem. 2005, 15, 3130-3132.
-
(2005)
Bioorg. Med. Chem
, vol.15
, pp. 3130-3132
-
-
Agarwal, A.1
Srivastava, K.2
Puri, S.K.3
Chauhan, P.M.S.4
-
79
-
-
84863834611
-
Lead optimization of antimalarial propafenone analogues
-
Lowes, D.; Pradhan, A.; Iyer, L. V.; Parman, T.; Gow, J.; Zhu, F.; Furimsky, A.; Lemoff, A.; Guiguemde, W. A.; Sigal, M.; Clark, J. A.; Wilson, E.; Tang, L.; Connelly, M. C.; DeRisi, J. L.; Kyle, D. E.; Mirsalis, J.; Guy, R. K. Lead optimization of antimalarial propafenone analogues. J. Med. Chem. 2012, 55, 6087-6093.
-
(2012)
J. Med. Chem
, vol.55
, pp. 6087-6093
-
-
Lowes, D.1
Pradhan, A.2
Iyer, L.V.3
Parman, T.4
Gow, J.5
Zhu, F.6
Furimsky, A.7
Lemoff, A.8
Guiguemde, W.A.9
Sigal, M.10
Clark, J.A.11
Wilson, E.12
Tang, L.13
Connelly, M.C.14
DeRisi, J.L.15
Kyle, D.E.16
Mirsalis, J.17
Guy, R.K.18
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