Synthesis and biological evaluation of piperazinyl-2-(benzo)thiophen/- furan-2-yl-acetonitriles as strecker reaction products

Letters in Drug Design and Discovery

Volumn 10, Issue 5, 2013, Pages 462-470

  Patel, Rahul V ^a   Patel, Jigar K ^b   Nile, Shivraj H ^a   Park, Se Won ^a  

^a Konkuk University   (South Korea)

^b SARDAR VALLABHBHAI NATIONAL INSTITUTE OF TECHNOLOGY   (India)

Author keywords

Antimicrobial activity; Catalyst; Furan, piperazine; Indium powder; Thiophehe

Indexed keywords

2 (4 (2 FLUOROPHENYL)PIPERAZIN 1 YL) 2 (FURAN 2 YL)ACETONITRILE; 2 (4 (2 FLUOROPHENYL)PIPERAZIN 1 YL) 2 (THIOPHEN 2 YL)ACETONITRILE; 2 (4 (4 FLUOROPHENYL)PIPERAZIN 1 YL) 2 (FURAN 2 YL)ACETONITRILE; 2 (4 (4 FLUOROPHENYL)PIPERAZIN 1 YL) 2 (THIOPHEN 2 YL)ACETONITRILE; 2 (4 (4 METHOXYPHENYL)PIPERAZIN 1 YL) 2 (THIOPHEN 2 YL)ACETONITRILE; 2 (BENZO[B]THIOPHEN 2 YL) 2 (4 (2 FLUOROPHENYL)PIPERAZIN 1 YL)ACETONITRILE; 2 (BENZO[B]THIOPHEN 2 YL) 2 (4 (2,3,4 TRIMETHOXYBENZYL)PIPERAZIN 1 YL)ACETONITRILE; 2 (BENZO[B]THIOPHEN 2 YL) 2 (4 (3 TRIFLUOROMETHYL)PIPERAZIN 1 YL)ACETONITRILE; 2 (BENZO[B]THIOPHEN 2 YL) 2 (4 (4 FLUOROPHENYL)PIPERAZIN 1 YL)ACETONITRILE; 2 (BENZO[B]THIOPHEN 2 YL) 2 (4 (4 METHOXYPHENYL)PIPERAZIN 1 YL)ACETONITRILE; 2 (BENZO[B]THIOPHEN 2 YL) 2 (4 (4 TRIFLUOROMETHYL)PIPERAZIN 1 YL)ACETONITRILE; 2 (BENZOFURAN 2 YL) 2 (4 (2 FLUOROPHENYL)PIPERAZIN 1 YL)ACETONITRILE; 2 (BENZOFURAN 2 YL) 2 (4 (2,3,4 TRIMETHOXYBENZYL)PIPERAZIN 1 YL)ACETONITRILE; 2 (BENZOFURAN 2 YL) 2 (4 (3 TRIFLUOROMETHYL)PHENYL)PIPERAZIN 1 YL)ACETONITRILE; 2 (BENZOFURAN 2 YL) 2 (4 (4 FLUOROPHENYL)PIPERAZIN 1 YL)ACETONITRILE; 2 (BENZOFURAN 2 YL) 2 (4 (4 METHOXYPHENYL)PIPERAZIN 1 YL)ACETONITRILE; 2 (BENZOFURAN 2 YL) 2 (4 (4 TRIFLUOROMETHYL)PHENYL)PIPERAZIN 1 YL)ACETONITRILE; 2 (FURAN 2 YL) 2 (4 (2,3,4 TRIMETHOXYBENZYL)PIPERAZIN 1 YL) 2 (FURAN 2 YL)ACETONITRILE; 2 (FURAN 2 YL) 2 (4 (3 (TRIFLUOROMETHYL)PIPERAZIN 1 YL) 2 (FURAN 2 YL)ACETONITRILE; 2 (FURAN 2 YL) 2 (4 (4 (TRIFLUOROMETHYL)PIPERAZIN 1 YL) 2 (FURAN 2 YL)ACETONITRILE; 2 (FURAN 2 YL) 2 (4 (4 METHOXYPHENYL)PIPERAZIN 1 YL) 2 (FURAN 2 YL)ACETONITRILE; 2 (THIOPHEN 2 YL) 2 (4 (2,3,4 (TRIMETHOXYBENZYL)PHENYL)PIPERAZIN 1 YL)ACETONITRILE; 2 (THIOPHEN 2 YL) 2 (4 (3 (TRIFLUOROMETHYL)PHENYL)PIPERAZIN 1 YL)ACETONITRILE; 2 (THIOPHEN 2 YL) 2 (4 (4 (TRIFLUOROMETHYL)PHENYL)PIPERAZIN 1 YL)ACETONITRILE; ACETONITRILE DERIVATIVE; AMPICILLIN; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; FLUCONAZOLE; GENTAMICIN; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; ASPERGILLUS NIGER; BACILLUS CEREUS; CANDIDA ALBICANS; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; ESCHERICHIA COLI; IN VITRO STUDY; INFRARED SPECTROSCOPY; KLEBSIELLA PNEUMONIAE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; STRECKER SYNTHESIS; STRUCTURE ACTIVITY RELATION;

EID: 84879773263     PISSN: 15701808     EISSN: 1875628X     Source Type: Journal    
DOI: 10.2174/1570180811310050014     Document Type: Article

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