Synthesis and antimalarial evaluation of a series of piperazinyl flavones

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 4, 2007, Pages 959-963

  Auffret, Gwenola ^a   Labaied, Mehdi ^b   Frappier, François ^c   Rasoanaivo, Philippe ^d   Grellier, Philippe ^b   Lewin, Guy ^a  

^a UNIVERSITÉ PARIS SACLAY   (France)

^b MUSÉUM NATIONAL D'HISTOIRE NATURELLE   (France)

^c CNRS   (France)

^d INSTITUT MALGACHE DE RECHERCHES APPLIQUÉES   (Madagascar)

Author keywords

Antimalarial drugs; Diosmin; Flavonoids; Piperazinyl chain; Plasmodium falciparum

Indexed keywords

2,3,4 TRIMETHOXYBENZYLPIPERAZINYL DERIVATIVE; ANTIMALARIAL AGENT; CHLOROQUINE; FLAVONE DERIVATIVE; PIPERAZINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SUBSTITUTION; DRUG SYNTHESIS; IN VITRO STUDY; MOUSE; NONHUMAN; PLASMODIUM FALCIPARUM; PLASMODIUM YOELII; STRAIN IDENTIFICATION; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTIMALARIALS; CELL LINE, TUMOR; CELL SURVIVAL; CHLOROQUINE; DRUG RESISTANCE; DRUG SCREENING ASSAYS, ANTITUMOR; FLAVONES; GENES, MDR; HUMANS; INDICATORS AND REAGENTS; MALARIA; MICE; PIPERAZINES; PLASMODIUM FALCIPARUM; STRUCTURE-ACTIVITY RELATIONSHIP;

PLASMODIUM FALCIPARUM; PLASMODIUM YOELII NIGERIENSIS;

EID: 33846681593     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.11.051     Document Type: Article

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