Synthesis and in vitro and in vivo antimycobacterial activity of isonicotinoyl hydrazones

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 20, 2005, Pages 4502-4505

  Sriram, Dharmarajan ^a   Yogeeswari, Perumal ^a   Madhu, Kasinathan ^a  

^a BIRLA INSTITUTE OF TECHNOLOGY AND SCIENCE   (India)

Author keywords

Antimycobacterial; Isoniazide derivatives

Indexed keywords

ACETOPHENONE DERIVATIVE; AMINE; ANTIMYCOBACTERIAL AGENT; FORMALDEHYDE; HYDRAZONE DERIVATIVE; ISONIAZID; ISONIAZID DERIVATIVE; MANNICH BASE; N' [1 [2 HYDROXY 3 (PIPERAZIN 1 YLMETHYL)PHENYL]ETHYLIDENE] ISONICOTINOHYDRAZIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; CHEMICAL REACTION; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; FEMALE; IN VITRO STUDY; IN VIVO STUDY; LABORATORY TEST; LUNG PARENCHYMA; MINIMUM INHIBITORY CONCENTRATION; MOLECULE; MOUSE; MYCOBACTERIOSIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHARMACOPHORE;

ANIMALS; ANTITUBERCULAR AGENTS; CERCOPITHECUS AETHIOPS; FEMALE; ISONIAZID; MICE; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM TUBERCULOSIS; VERO CELLS;

BACTERIA (MICROORGANISMS); MURINAE; MYCOBACTERIUM TUBERCULOSIS;

EID: 24344459482     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.07.011     Document Type: Article

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