Synthesis and antimalarial activity of hydroxyethylpiperazine derivatives

European Journal of Medicinal Chemistry

Volumn 44, Issue 3, 2009, Pages 1363-1368

  Cunico, Wilson ^a   Gomes, Claudia R B ^a   Moreth, Marcele ^a   Manhanini, Diogo P ^a   Figueiredo, Isabela H ^a   Penido, Carmen ^a   Henriques, Maria G M O ^a   Varotti, Fernando P ^b   Krettli, Antoniana U ^b  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

Author keywords

Hydroxyethylpiperazine; Malaria; Piperazine

Indexed keywords

ANTIMALARIAL AGENT; BENZYLPIPERAZINE DERIVATIVE; CHLOROQUINE; EPOXIDE; HYDROXYETHYLPIPERAZINE DERIVATIVE; LOPINAVIR; N TERT BUTYLOXYCARBONYL PHENYLALANINE EPOXIDE; PIPERAZINE DERIVATIVE; SAQUINAVIR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIMALARIAL ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; IN VITRO STUDY; MOUSE; NONHUMAN; PLASMODIUM FALCIPARUM;

ANIMALS; ANTIMALARIALS; CHROMATOGRAPHY, LIQUID; DRUG EVALUATION, PRECLINICAL; ERYTHROCYTES; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; PIPERAZINES; PLASMODIUM FALCIPARUM;

EID: 60549100346     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2008.04.009     Document Type: Article

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