Synthesis and biological evaluation of novel piperazine derivatives of flavone as potent anti-inflammatory and antimicrobial agent

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 20, 2012, Pages 6385-6390

  Hatnapure, Girish D ^a   Keche, Ashish P ^a   Rodge, Atish H ^c   Birajdar, Satish S ^a   Tale, Rajesh H ^c   Kamble, Vandana M ^a,b  

^a Maharashtra Udaygiri Mahavidayla ^*  (India)

^b INSTITUTE OF SCIENCE   (India)

^c SWAMI RAMANAND TEERTH MARATHWADA UNIVERSITY   (India)

Author keywords

Anti inflammatory; Antibacterial; Antifungal activity; Chrysin; Flavone; Piperazine derivatives

Indexed keywords

5,7 DIMETHOXY 2 (PIPERAZIN 1 YLMETHYL) 4H CHROMEN 4 ONE DERIVATIVE; 6 METHOXY 2 (PIPERAZIN 1 YL) 4H CHROMEN 4 ONE DERIVATIVE; CIPROFLOXACIN; DEXAMETHASONE; FLAVONE DERIVATIVE; INTERLEUKIN 6; MICONAZOLE; PIPERAZINE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN;

ANTI-INFECTIVE AGENTS; ANTI-INFLAMMATORY AGENTS; BACTERIA; BACTERIAL INFECTIONS; FLAVONES; FUNGI; HUMANS; INTERLEUKIN-6; MICROBIAL SENSITIVITY TESTS; MYCOSES; PIPERAZINES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84866743102     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.08.071     Document Type: Article

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