Supercritical Fluid Extraction Using CO2: Main Applications and Future Perspectives

Separation Science and Technology (Philadelphia)

Volumn 48, Issue 18, 2013, Pages 2741-2760

  Machado, Bruna Aparecida Souza ^a,b   Pereira, Camila Gambini ^c   Nunes, Silmar Baptista ^a   Padilha, Francine Ferreira ^d   Umsza Guez, Marcelo Andres ^e  

^a Servico Nacional de Aprendizagem Industrial   (Brazil)

^b FEDERAL UNIVERSITY OF SERGIPE   (Brazil)

^c FEDERAL UNIVERSITY OF RIO GRANDE DO NORTE   (Brazil)

^d TIRADENTES UNIVERSITY   (Brazil)

^e FEDERAL UNIVERSITY OF BAHIA   (Brazil)

Author keywords

food; natural compounds; supercritical extraction patents; supercritical fluid extraction

Indexed keywords

CHEMICAL RESIDUES; FUTURE PERSPECTIVES; NATURAL COMPOUNDS; PATENT DOCUMENTS; SCIENTIFIC ARTICLES; SCIENTIFIC PAPERS; SUPERCRITICAL EXTRACTION; SUPERCRITICAL FLUID EXTRACTION (SFE);

CARBON DIOXIDE; FOOD PRODUCTS; PATENTS AND INVENTIONS;

SUPERCRITICAL FLUID EXTRACTION;

EID: 84887865145     PISSN: 01496395     EISSN: 15205754     Source Type: Journal    
DOI: 10.1080/01496395.2013.811422     Document Type: Review

References (196)

1. Brunner, G. (2000) Fractionation of fats with supercritical carbon dioxide. Eur. J. Lipid Sci. Technol., 102 (3): 240 - 244.
2. Budich, M.; Brunner, G. (2003) Supercritical fluid extraction of ethanol from aqueous solutions. J. Supercrit. Fluids, 25 (1): 45 - 55.
3. King, M.B.; Boot, T.R. (1993) Extraction of Natural Products Using Near-Critical Solvents, 1st ed.; Chapman and Hall: London, UK.
4. Bundschuh, G. (1986) High pressure extraction in the food technology. ZFL, 8: 525 - 534.
5. Brunner, G. (1994) Gas Extraction: An Introduction to Fundamentals of Supercritical Fluids and the Application to Separation Process, 1st ed.; Steikopff Darmastadt: New York.
6. Herrero, M.; Mendiola, J.A.; Cifuentes, A.; Ibáñes, E. (2010) Supercritical fluid extraction: Recent advances and applications. J. Chromatogr., 1217 (16): 2495 - 2511.
7. Chiu, K.L.; Cheng, Y.C.; Chen, J.H.; Chang, C.J.; Yang, P.W. (2002) Supercritical fluids extraction of Ginkgo ginkgolides and flavonoids. J. Supercrit. Fluids, 24 (1): 77 - 87.
8. Nalawade, S.P.; Picchioni, F.; Janssen, L.P.B.M. (2006) Supercritical carbon dioxide as a green solvent for processing polymer melts: Processing aspects and applications. Progress Polym. Sci., 31 (1): 19 - 43.
9. Wang, L.; Yang, B.; Dua, X.; Yi, C. (2008) Optimization of supercritical fluid extraction of flavonoids from Pueraria lobata. Food Chem., 108 (2): 737 - 741.
10. Temelli, F. (2009) Perspectives on supercritical fluid processing of fats and oils. J. Supercrit. Fluids, 47 (3): 583 - 590.
11. Gomes, P.B.; Mata, V.G.; Rodrigues, A.E. (2007) Production of rose geranium oil using supercritical fluid extraction. J. Supercrit. Fluids, 41 (1): 50 - 60.
12. Pourmortazavi, S.M.; Hajimirsadeghi, S.S. (2007) Supercritical fluid extraction in plant essential and volatile oil analysis. J. Chromatogr., 1162 (1-2): 2 - 24.
13. Brunner, G. (2005) Supercritical fluids: Technology and application to food processing. J. Food Eng., 67 (1-2): 21-33.
14. Herrero, M.; Cifuentes, A.; Ibáñes, E. (2006) Sub- and supercritical fluid extraction of functional ingredients from different natural sources: Plants, food-by-products, algae and microalgae. Food Chem., 98 (1): 136 - 148.
15. Mattea, F.; Martin, A.; Cocero, M.J. (2009) Carotenoid processing with supercritical fluids. J. Food Eng., 93 (3): 255 - 265.
16. Mendiola, J.A.; Herrero, M.; Cifuentes, A.; Ibáñes, E. (2007) Use of compressed fluids for sample preparation: Food applications. J. Chromatogr., 8 (1152): 234 - 46.
17. Leal, P.F.; Braga, M.E.M.; Sato, D.N.; Carvalho, J.E.; Marques, M.O.M.; Meireles, M.A.A. (2003) Functional properties of spice extracts obtained via supercritical fluid extraction. J. Agric. Food Chem., 51 (9): 2520 - 2525.
18. Pereira, C.G.; Meireles, M.A.A. (2007) Economic analysis of rosemary, fennel and anise essential oils obtained by supercritical fluid extraction. Flavor Fragrance J., 22 (5): 407 - 413.
19. Safaralie, A.; Fatemi, S.; Salimi, A. (2010) Experimental design on supercritical extraction of essential oil from valerian roots and study of optimal conditions. Food Bioproducts Processing, 88 (2): 312 - 318.
20. Biscaia, D.; Ferreira, S.R.S. (2009) Propolis extracts obtained by low pressure methods and supercritical fluid extraction. J. Supercrit. Fluids, 51 (1): 17 - 23.
21. Zhang, S.; Xi, J.; Wang, C. (2005) High hydrostatic pressure extraction of flavonoids from propolis. J. Chem. Technol. Biotechnol., 80 (1): 50 - 54.
22. Topal, U.; Sasaki, M.; Goto, M.; Hayakawa, K. (2006) Extraction of lycopene from tomato skin with supercritical carbon dioxide: Effect of operating conditions and solubility analysis. J. Agric. Food Chem., 54 (15): 5604 - 5610.
23. Huang, W.; Li, Z.; Niu, H.; Li, D.; Zhang, J. (2008) Optimization of operating parameters for supercritical carbon dioxide extraction of lycopene by response surface methodology. J. Food Eng., 89 (3): 298 - 302.
24. La-Fuente, J.C.; Oyarz, B.; Quezada, N.; Del-Valle, J.M. (2006) Solubility of carotenoid pigments (lycopene and astaxanthin) in supercritical carbon dioxide. Fluid Phase Equilib., 247 (1): 90 - 95.
25. Gelmez, N.; Kincal, N.S.; Yener, M.E. (2009) Optimization of supercritical carbon dioxide extraction of antioxidants from roasted wheat germ based on yield, total phenolic and tocopherol contents, and antioxidant activities of the extracts. J. Supercrit. Fluids, 48 (3): 217 - 224.
26. Meei, M.G.; Keat, T.L., Bhatia, S. (2009) Supercritical carbon dioxide extraction of xanthones with antioxidant activity from Garcinia mangostana: Characterization by HPLC/LC-ESI-MS. J. Supercrit. Fluids, 49 (3): 330 - 337a.
27. 2 and different co-solvents. J. Supercrit. Fluids, 45 (2): 189 - 194.
28. 2 applications in the processing of polymers. Ind. Eng. Chem. Res., 42 (25): 6431 - 6456.
29. Sameer, P.N.; Picchiono, F.; Janssen, L.P.B.M. (2006) Supercritical carbon dioxide as a green solvent for processing polymer melts: Processing aspects and applications. Prog. Polym. Sci., 31 (1): 19 - 43.
30. Wang, W.; Yang, H.J.; Hu, J.; Guo, C.Y. (2009) Extraction of metal ions with non-fluorous bipyridine derivatives as chelating ligands in supercritical carbon dioxide. J. Supercrit. Fluids, 51 (2): 181 - 187.
31. Albarelli, J.; Rabelo, R.B. Santos, D.T.; Beppu, M.M. Meireles, M.A.A. (2011) Effects of supercritical carbon dioxide on waste banana peels for heavy metal removal. J. Supercrit. Fluids, 58 (3): 343 - 351.
32. 3+ ions from a solid matrix using bis (2,4,4-trimethylpentyl) dithiophosphinic acid + tributylphosphate. Chem. Eng. Res. Des., 89 (6): 827 - 835.
33. Meei, M.G.; Keat, T.L., Bhatia, S. (2009) Supercritical ethanol technology for the production of biodiesel: Process optimization studies. J. Supercrit. Fluids, 49 (2): 286 - 292b.
34. Wen, D.; Jiang, H.; Zhang, K. (2009) Supercritical fluids technology for clean biofuel production. Prog. Nat. Sci., 19 (3): 273 - 284.
35. Paulo, C.I.; Diaz, M.S.; Bringnole, E.A. (2009) Energy Consumption Minimization in Bioethanol Dehydration with Supercritical Fluids. Comput. Aided Chem. Eng., 27: 1833 - 1838.
36. 2. 9° Latin American Symposium on Food Science, Unicamp, Campinas, 2011.
37. 2 supercrítico. Sci. Food Technol., 17 (4): 405 - 407.
38. Akinlua, A.; Torto, N.; Ajayi, T.R. (2008) Supercritical fluid extraction of aliphatic hydrocarbons from Niger Delta sedimentary rock. J. Supercrit. Fluids, 45 (1): 57 - 63.
39. Martinez-Correa, H.A.; Gomes, D.C.A.; Kanehisa, S.L.; Cabral, F.A. (2010) Measurements and thermodynamic modeling of the solubility of squalene in supercritical carbon dioxide. J. Food Eng., 96: 43 - 50.
40. Castro-Vargas, H.I.; Benelli, P.; Ferreira, S.R.S.; Parada-Alfonso, F. (2013) Supercritical fluid extracts from tamarillo (Solanum betaceum Sendtn) epicarp and its application as protectors against lipid oxidation of cooked beef meat. J. Supercrit. Fluids, 76: 17 - 23.
41. Pereira, C.G.; Rosa, P.T.V.; Meireles, M.A.A. (2007) Extraction and isolation of indole alkaloids from Tabernaemontana catharinensis: Technical and economical analysis. J. Supercrit. Fluids, 40: 232 - 238.
42. Rodrigues, R.F.; Tashima, A.K.; Pereira, R.M.S.; Mohamed, R.S.; Cabral, F.A. (2008) Coumarin solubility and extraction from emburana (Torresea cearensis) seeds with supercritical carbon dioxide. J. Supercrit. Fluids, 43: 375 - 382.
43. 2. J. Agric. Food Chem., 47: 3804 - 3808.
44. Catchpole, O.J.; von Kamp, J.C. (1997) Phase equilibrium for the extraction of squalene from shark liver oil using supercritical carbon dioxide. Ind. Eng. Chem. Res., 36: 3762 - 8.
45. Shojaee, S.A.; Rajaei, H.; Hezave, A.Z.; Lashkarbolooki, M.; Esmaeilzadeh, F. (2013) Experimental measurement and correlation for solubility of piroxicam (a Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)) supercritical carbon dioxide. J. Supercrit. Fluids, in press.
46. Su, C.S.; Chen, Y.P. (2007) Correlation for the solubilities of pharmaceutical compounds in supercritical carbon dioxide. Fluid Phase Equilibr., 254: 167 - 173.
47. 2. J. Supercrit. Fluids, 4: 32 - 39.
48. Sane, A.; Taylor, S.; Sun, Y.P.; Thies, M.C. (2004) A semicontinuous flow apparatus for measuring the solubility of opaque solids in supercritical solutions. J. Supercrit. Fluids, 28: 277 - 285.
49. Yu, E.; Richter, M.; Chen, P.; Wang, X.; Zhang, Z.; Tavlarides, L.L. (1995) Solubilities of polychlorinated biphenyls in supercritical carbon dioxide. Ind. Eng. Chem. Res., 34: 340 - 346.
50. Shena, B.; Feng, L.; Li, S.; Li, H. (2013) Correlating and predicting the solubilities of polycyclic aromatic hydrocarbons in supercritical fluids using the compressed gas model and the reference solubilities. Fluid Phase Equilibr., 337: 100 - 108.
51. 2 with EoS/G E models. Fluid Phase Equilibr., 102: 121-141.
52. 2 during thermal cracking of heavy paraffins under supercritical conditions. Ind. Eng. Chem. Res., 36: 4445 - 4451.
53. Pereira, C.G.; Meireles, M.A.A. (2010) Supercritical fluid extraction of bioactive compounds: Fundamentals, applications and economic perspectives. Food Bioprocess Tech., 3 (3): 340 - 372.
54. Anekpankul, T.; Goto, M.; Sasaki, M.; Pavasant, P.; Shotipruk, A. (2007) Extraction of anticancer damnacanthal from roots of Morinda citrifolia by subcritical water. Sep. Purif. Technol., 55 (3): 343 - 349.
55. Bludworth, J.; Knopf, F.C. (1993) Reactive extraction of lignin from wood using supercritical ammonia-water mixtures. J. Supercrit. Fluids, 6 (4): 249 - 254.
56. Shen, J.W.; Domański, K.B.; Kitao, O.; Nakanishi, K. (1995) Computer simulation on supercritical carbon dioxide fluid a potential model for the benzene-carbon dioxide system from ab initio calculations. Fluid Phase Equilibr., 104 (1): 375 - 390.
57. Olsen, M.H.N.; Salomão, G.C.; Drago, V.; Fernandes, C.; Horn Jr., A.; Cardozo, F.L.; Antunes, O.A.C. (2005) Oxidation of cyclohexane in supercritical carbon dioxide catalyzed by iron tetraphenylporphyrin. J. Supercrit. Fluids, 34 (2): 119 - 124.
58. Glisic, S.B.; Misicb, D.R.; Stamenica, M.D.; Zizovica, I.T.; Asaninb, R.M.; Skala, D.U. (2007) Supercritical carbon dioxide extraction of carrot fruit essential oil: Chemical composition and antimicrobial activity. Food Chem., 105 (1): 346 - 352.
59. Brunner, G.; Peter, S. (1982) On the solubility of glycerides and fatty acids incompressed gases in the presence of an entrainer. Sep. Sci. Technol., 17 (1): 199 - 214.
60. Shende, R.V.; Lombardo, S.J. (2002) Supercritical extraction with carbon dioxide and ethylene of poly(vinyl butyral) and dioctyl phthalate from multilayer ceramic capacitors. J. Supercrit. Fluids, 23 (2): 153 - 162.
61. Hamdan, S.; Daood, H.G.; Toth-Markus, M.; Illés, V. (2008) Extraction of cardamom oil by supercritical carbon dioxide and sub-critical propane. J. Supercrit. Fluids, 44 (1): 25 - 30.
62. Banaei, M.; Florusse, L.J.; Raeissi, S.; Peters, C.J. (2012) High-pressure vapor-liquid equilibria of methanol + propylene: Experimental and modeling with SAFT. J. Supercrit. Fluids, 63: 25 - 30.
63. Kershaw, J.R.; Smart, P.J. (1993) Extraction of coal-tar pitch with supercritical toluene. J. Supercrit. Fluids, 6 (3): 155 - 163.
64. Ho, C.H.L.; Cacece, J.E.; Mazza, G. (2007) Extraction of lignans, proteins and carbohydrates from flaxseed meal with pressurized low polarity water. Food Sci. Technol., 40 (9): 1637 - 1647.
65. Straver, E.J.M.; Roo, J.L.; Peters, C.J. Swaan-Arons, J. (1998) Phase behavior of the binary system propane and tristearin. J. Supercrit. Fluids, 11 (3): 139 - 150.
66. 2 and propane at superand subcritical conditions. J. Supercrit. Fluids, 17 (2): 177 - 186.
67. Freitas, L.S.; Oliveira, J.V.; Dariva, C.; Jacques, R.A.; Caramão, E.B. (2008) Extraction of grape seed oil using compressed carbon dioxide and propane: extraction yields and characterization of free glycerol compounds. J. Agr. Food Chem., 56 (8): 2558 - 2564.
68. 2 and co-solvents: A study of the antioxidant activity of the extracts. J. Supercrit. Fluids, 24 (1): 57 - 76.
69. 2 plus water: extraction kinetics and identification of extracted components. J. Food Eng., 57 (2): 125 - 134.
70. Sun, Y.; Liu, Z.; Wang, J.; Tian, W.; Zhou, H.; Zhu, L.; Zahng, C. (2008) Supercritical fluid extraction of paeonol from Cynanchum paniculatum (Bge.) Kitag. and subsequent isolation by high-speed counter-current chromatography coupled with high-performance liquid chromatography-photodiode array detector. Sep. Purif. Technol., 64 (2): 221 - 226.
71. You, G.S.; Lin, S.C.; Chen, C.R.; Tsai, W.C.; Chang, C.J.; Huang, W.W. (2002) Supercritical carbon dioxide extraction enhances flavonoids in water-soluble propolis. J. Chin. Inst. Chem. Eng., 33 (3): 233 - 241.
72. Saldaña, M.D.A.; Zetzl, C.; Mohamed, R.S.; Brunner, G. (2002) Extraction of methylxanthines from guarana seeds, mate leaves, and cocoa beans using supercritical carbon dioxide and ethanol. J. Agr. Food Chem., 50 (17): 4820 - 4826.
73. Catchpole, O.J.; Grey, J.B.; Mitchel, K.A.; Lan, J.S. (2004) Supercritical antisolvent fractionation of propolis tincture. J. Supercrit. Fluids, 29 (1-2): 97 - 106.
74. Lee, Y.N.; Chen, C.R.; Yang, H.L.; Lin, C.C.; Chang, C.M.J. (2007) Isolation and purification of 3,5-diprenyl-4-hydroxycinnamic acid (artepillin C) in Brazilian propolis by supercritical fluid extractions. Sep. Purif. Technol., 54 (1): 130 - 138.
75. Kitzberger, C.S.G.; Smânia, A.J.; Pedrosa, R.C.; Ferreira, S.R.S. (2007) Antioxidant and antimicrobial activities of shiitake (Lentinula edodes) extracts obtained by organic solvents and supercritical fluids. J. Food Eng., 80 (2): 631 - 638.
76. Chen, C.R.; Lee, Y.N.; Lee, M.R., Chang, C.M.J. (2009) Supercritical fluids extraction of cinnamic acid derivatives from Brazilian propolis and the effect on growth inhibition of colon cancer cells. J. Taiwan Inst. Chem. Eng., 40 (2): 130 - 135.
77. Chen, C.R.; Shen, C.T.; Wu, J.J.; Yang, H.L., Hsu, S.L.; Chang, C.M.J. (2009) Precipitation of sub-micron particles of 3,5-diprenyl-4-hydroxycinnamic acid in Brazilian propolis from supercritical carbon dioxide anti-solvent solutions. J. Supercrit. Fluids, 50 (2): 176 - 182.
78. Azevedo, A.B.A.; Kopcak, U.; Mohamed, R.S. (2003) Extraction of fat from fermented Cupuaçu seeds with supercritical solvents. J. Supercrit. Fluids, 27 (2): 223 - 237.
79. Yépez, B.; Espinosa, M.; López, S.; Bolaños, G. (2002) Producing antioxidant fractions from herbaceaus matrices by supercritical fluid extraction. Fluid Phase Equilibr., 194-197: 879 - 884.
80. Mohamed, R.S. (1997) Extraction and fractionation of naturally occurring products with supercritical fluids. Sci. Food Technol., 17 (4): 344 - 353.
81. Dohrn, R.; Brunner, G. (1995) High-pressure fluid-phase equilibria: Experimental methods and systems investigated (1988-1993). Fluid Phase Equilibr., 106 (1-2): 213 - 282.
82. Moura, L.S.; Carvalho, R.N.; Stefanini, M.B.; Ming, L.C.; Meireles, M.A. (2005) Supercritical fluid extraction from fennel (Foeniculum vulgare): global yield, composition and kinetic data. J. Supercrit. Fluids, 35 (3): 212 - 219.
83. Pereira, C.G.; Gualtieri, I.P.; Meireles, M.A.A. (2008) Effect of different extraction processes on the recovery of extracts from Achyrocline satureioides D.C.: An evaluation of antioxidant activity. Sep. Sci. Technol., 43 (6): 1549 - 1563.
84. Braga, M.E.M. (2005) Obtaining bioactive compounds from Curcuma longa L. and Lippia alba M. by supercritical technology: global yields, extraction kinetics, chemical composition, and usage of the starchy residue. PhD Thesis, School of Food Engineering, University of Campinas, SP, Brazil.
85. Seabra, I.J.; Braga, M.E.M.; Batista, M.T.P.; Sousa, H.C. (2010) Fractioned high pressure extraction of anthocyanins from elderberry (Sambucus nigra L.) pomace. Food Bioprocess Technol., 3: 674 - 683.
86. Yonei, Y.; Ohinata, H.; Yoshida, R.; Shimizu, Y.; Yokoyama, C. (1995) Extraction of ginger flavor with liquid or supercritical carbon dioxide. J. Supercrit. Fluids, 8 (2): 156 - 161.
87. 2 + ethanol: An evaluation of the process variables and the raw material origin. J. Supercrit. Fluids, 30 (1): 51-61.
88. Setianto, W.B.; Yoshikawa, S.; Smith Jr., R.L.; Inomata, H.; Florusse, L.J.; Peters, C.J. (2009) Pressure profile separation of phenolic liquid compounds from cashew (Anacardium occidentale) shell with supercritical carbon dioxide and aspects of its phase equilibria. J. Supercrit. Fluids, 48 (3): 203 - 210.
89. King, J.W. (2000) Advances in critical fluid technology for food processing. Food Sci. Technol., 14 (4): 186 - 191.
90. Perrut, M.; Clavier, J.Y. (2003) Supercritical fluid formulation: Process cand scale-up. Ind. Eng. Chem. Res., 42 (25): 6375 - 6383.
91. Meireles, M.A.A. (2003) Supercritical extraction from solid process design data (2001-2003). Cur. Opin. Solid St. M. Sci., 7 (4-5): 321 - 330.
92. Bhat, V.B.; Madyastha, K.M. (2000) C-Phycocyanin: A potent peroxyl radical scavenger in vivo and in vitro. Biochem. Bioph. Res. Co., 275 (1): 20 - 25.
93. Piñero-Estrada, J.E.; Bermejo-Bascós, P.; Villar, F.A.M. (2001) Antioxidant activity of different fractions of Spirulina platensis protean extract. Farmaco, 56 (5-7): 497 - 500.
94. Magnan, C.; Badens, E.; Commenges, N.; Charbit, G. (2000) Soy lecithin micronization by precipitation with a compressed fluid antisolvent: Influence of process parameters. J. Supercrit. Fluids, 19 (1): 69 - 77.
95. Sun, M.; Temelli, F. (2006) Supercritical carbon dioxide extraction of carotenoids from carrot using canola oil as a continuous co-solvent. J. Supercrit. Fluids, 37 (3): 397 - 408.
96. 2: Optimisation of the extraction conditions. J. Food Eng., 78 (2): 488 - 493.
97. Ruivo, R.; Couto, R.; Simoes, P.C. (2008) Supercritical carbon dioxide fractionation of the model mixture squalene/oleic acid in a membrane contactor. Sep. Purif. Technol., 59 (3): 231 - 237.
98. Stashenko, E.E.; Jaramillo, B.E.; Martínez, J.R. (2004) Comparison of different extraction methods for the analysis of volatile secondary metabolites of Lippia Alba (Mill.) N. E. Brown, grown in Colombia, and evaluation of its in vitro antioxidant activity. J. Chromatogr., 1025 (1): 93 - 103.
99. Li, J.; Zhang, M.; Zheng, T. (2009) The in vitro antioxidant activity of lotus germ oil from supercritical fluid carbon dioxide extraction. Food Chem., 115 (3): 939 - 944.
100. Ixtaina, V.Y.; Vega, A.; Nolasco, S.M.; Tomás, M.C.; Gimeno, M.; Bárzana, E.; Tecante, A. (2010) Supercritical carbon dioxide extraction of oil from Mexican chia seed (Salvia hispanica L.): Characterization and process optimization. J. Supercrit. Fluids, 55 (1): 192 - 199.
101. Ribeiro, M.A.; Bernardo-Gil, M.G.; Esquível, M.M. (2001) Melissa officinalis L.: study of antioxidant activity in supercritical residues. J. Supercrit. Fluids, 21 (1): 51 - 60.
102. Yamini, Y.; Khajeh, M.; Ghasemi, E.; Mirza, M.; Javidnia, K. (2008) Comparison of essential oil compositions of Salvia mirzayanii obtained by supercritical carbon dioxide extraction and hydrodistillation methods. Food Chem., 108 (1): 341 - 346.
103. 2 extraction of essential oil and oleoresin from chamomile (Chamomilla recutita [L.] Rauschert). J. Supercrit. Fluids, 21 (3): 245 - 256.
104. 2. J. Supercrit. Fluids, 56 (2): 174 - 178.
105. Kotnik, P.; Skerget, M.; Knez, Z. (2007) Supercritical fluid extraction of chamomile flower heads: Comparison with conventional extraction, kinetics and scale-up. J. Supercrit. Fluids, 43 (2): 192 - 198.
106. 2 extraction of Salvia officinalis L. J. Supercrit. Fluids, 40 (2): 139 - 145.
107. Alhaj, N.A.; Shamsudin, M.N.; Zamri, H.F.; Abdullah, R. (2008) Extraction of essential oil from Nigella sativa using supercritical carbon dioxide: Study of antibacterial activity. Am. J. Pharmacol., 3 (4): 225 - 228.
108. Grigonis, D.; Venskutonis, P.R.; Sivik, B.; Sandahl, M.; Eskilsson, C. (2005) Comparison of different extraction techniques for isolation of antioxidants from sweet grass (Hierochloe odorata). J. Supercrit. Fluids, 33 (3): 223 - 233.
109. Ruetsch, L.; Daghero, J.; Mattea, M. (2003) Supercritical extraction of solid matrices. Model formulation and experiments. Latin Am. Appl. Res., 33 (2): 103 - 107.
110. Ramírez, P.; Senoráns, F.J.; Ibañes, E.; Reglero, G. (2004) Separation of rosemary antioxidant compounds by supercritical fluid chromatography on coated packed capillary columns. J. Chromatogr., 1057 (1-2): 241 - 245.
111. Goli, A.H.; Barzegar, M.; Sahara, M.A. (2005) Antioxidant activity and total phenolic compounds of pistachio (Pistachia vera) hull extracts. Food Chem., 92 (3): 521 - 525.
112. Quispe-Condori, S.; Foglio, M.A.; Rosa, P.T.V.; Meireles, M.A.A. (2008) Obtaining β-caryophyllene from Cordia verbenacea de Candolle by supercritical fluid extraction. J. Supercrit. Fluids, 46 (1): 27 - 32.
113. 2 and by steam distillation. J. Supercrit. Fluids, 48 (1): 15 - 20.
114. Guan, W.; Li, S.; Yan, R.; Tang, S.; Quan, C. (2007) Comparison of essential oils of clove buds extracted with supercritical carbon dioxide and other three traditional extraction methods. Food Chem., 101 (4): 1558 - 1564.
115. Cao, H.; Xiao, J.B.; Xu, M. (2007) Comparison of volatile components of Marchantia convoluta obtained by supercritical carbon dioxide extraction and petrol ether extraction. J. Food Compos. Anal., 20 (1): 45 - 51.
116. 2. J. Supercrit. Fluids, 54 (2): 171 - 177.
117. Özcan, A.; Özcan, A.S. (2004) Comparison of supercritical fluid and Soxhlet extractions for the quantification of hydrocarbons from Euphorbia macroclada. Talanta, 64 (2): 491 - 4958.
118. Felfoldi-Gáva, A.; Szarka, S.; Simándi, B.; Blazics, B.; Simon, B.; Kéry, A. (2012) Supercritical fluid extraction of Alnus glutinosa (L.) Gaertn. J. Supercrit. Fluids, 61: 55 - 61.
119. 2: Kinetic data, chemical composition and selectivity of diterpenes. J. Supercrit. Fluids, 52 (1): 62 - 70.
120. Marcucci, M.C.; Ferreres, F.; Guarcía-Viguera, C.; Bankova, V.S.; De Castro, S.L.; Dantas, A.P.; Valente, P.H.M.; Paulino, N. (2001) Phenolic compounds from Brazilian própolis with pharmacollogical activities. J. Ethnopharmacol., 74 (2): 105 - 112.
121. Park, Y.K.; Alencar, S.M.; Scamparini, A.R.P.; Aguiar, C.L. (2002) Propolis produced in South Brazil, Argentine and Uruguay: Phytochemical evidence for the plant origin. Rural Sci., 32 (6): 997 - 1003.
122. Cunha, I.B.S.; Sawaya, A.C.H.F.; Caetano, F.M.; Shimizu, M.T.; Marcucci, M.C.; Drezza, F.T.; Povia, G.S.; Carvalho, P.O. (2004) Factors that Influence the yield and composition of Brazilian propolis extracts. J. Braz. Chem. Soc., 15 (6): 964 - 970.
123. Nagai, T.; Inoue, R.; Inoue, H.; Suzuki, N. (2003) Preparation and antioxidant properties of water extract of propolis. Food Chem., 80 (1): 29-33.
124. Kumazawa, S.; Hamasaka, T.; Nakayama, T. (2004) Antioxidant activity of propolis of various geographic origin. Food Chem., 84 (3): 329 - 339.
125. Wang, B.J.; Lien, Y.H.; Yu, Z.R. (2004) Supercritical fluid extractive fractionation study of the antioxidant activities of propolis. Food Chem., 86 (2): 237 - 243.
126. Lu, L.C.; Chen, Y.W.; Chou, C.C. (2005) Antibacterial activity of propolis against Staphylococcus aureus. Inter. J. Food Microbiol., 102 (2): 213 - 220.
127. Antungulu, G.G.; Toshitaka, U.; Fumihiko, T.; Daisuke, H. (2008) Effect of vapors from fractionated samples of propolis on microbial and oxidation damage of rice during storage. J. Food Eng., 88: 341 - 352.
128. Paulino, N.; Abreu, S.R.L.; Uto, Y.; Koyama, D.; Nagasawa, H.; Hori, H.; Dirsch, V.M.; Vollmar, A.M.; Scremin, A.; Bretz, W.A. (2008) Anti-inflamatory effects of a bioavailable compound, Artepillin C, in Brazilian propolis. Eur. J. Pharmacol., 587 (1-3): 296 - 301.
129. Ito, J.; Chang, F.R.; Wang, H.K.; Park, Y.K.; Ikegaki, M.; Kilgore, N.; Lee, K.H. (2001) Anti-HIV activity of moronic acid derivatives and the new melliferone-related triterpenoid isolated from Brazilian própolis. J. Nat. Prod., 64 (10): 1278 - 1281.
130. Wu, J.; Luyu, Q. Supercritical multiple extraction of bee glue. Chinese Patent, 1258511, 2000 July 05.
131. Paviani, C.L.; Dariva, C.; Marcucci, M.C.; Cabral, F.A. (2010) Surpercritical cabon dioxide selectivity to fracionate phenolic compounds from the dry ethanolic extract of propolis. J. Food Proc. Eng., 33 (1): 15 - 27.
132. 2. J. Am. Chem. Soc., 85 (1): 83 - 89.
133. Martínez, M.L.; Mattea, M.A.; Maestri, D.M. (2008) Pressing and supercritical carbon dioxide extraction of walnut oil. J. Food Eng., 88 (3): 399 - 404.
134. Sánchez-Vicente, Y.; Cabañas, A.; Renuncio, J.A.R.; Pando, C. (2009) Supercritical fluid extraction of peach (Prunus persica) seed oil using carbon dioxide and ethanol. J. Supercrit. Fluids, 49 (2): 167 - 173.
135. Bhattacharjee, P.; Singhal, R.S.; Tiwari, S.R. (2007) Supercritical carbon dioxide extraction of cottonseed oil. J. Food Eng., 79 (3): 892 - 898.
136. Gomez-Pietro, M.S.; Caja, M.M.; Herraiz, M.; Santa-Maria, G. (2003) Supercritical fluid extraction of all-trans-Lycopene from Tomato. J. Agric. Food Chem., 51 (1): 3 - 7.
137. Vági, E.; Simándi, B.; Vásárhelyine, K.P.; Daood, H.; Kéry, A.; Doleschall, F.; Nagy, B. (2007) Supercritical carbon dioxide extraction of carotenoids, tocopherols and sitosterols from industrial tomato by-products. J. Supercrit. Fluids, 40 (2): 218 - 226.
138. 2 with ethanol as co-solvent. J. Supercrit. Fluids, 41 (1): 61 - 67.
139. Montañés, F.; Olano, A.; Reglero, G.; Ibáñez, E.; Fornari, T. (2009) Supercritical technology as an alternative to fractionate prebiotic galactooligosaccharides. Sep. Purif. Technol., 66 (2): 383 - 389.
140. Perretti, G.; Motori, A.; Bravi, E.; Favati, F.; Montanari, L.; Fantozzi, P. (2007) Supercritical carbon dioxide fractionation of fish oil fatty acid ethyl esters. J. Supercrit. Fluids, 40 (3): 349 - 353.
141. Chang, L.H.; Shen, C.T.; Hsieh, S.J.; Hsu, S.L.; Chang, H.C.; Chang, C.M.J. (2008) Recovery and enhancement of unsaturated fatty acids in soft-shelled turtle fish oil using supercritical carbon dioxide and associated catalase release activity. Separation and Purification Technol., 64 (2): 213 - 220.
142. 2. J. Food Eng., 89 (4): 472 - 478.
143. Espinosa, S.; Díaz, M.S.; Brignole, E.A. (2008) Food additives obtained by supercritical extraction from natural sources. J. Supercrit. Fluids, 45 (2): 213 - 219.
144. Rubio-Rodríguez, N.; Diego, S.M.; Beltrán, S.; Jaime, I.; Sanz, M.T.; Rovira, J. (2012) Supercritical fluid extraction of fish oil from fish by-products: A comparison with other extraction methods. J. Food Eng., 109 (2): 238 - 248.
145. Bernal, J.L.; Nozal, M.J.; Toribio, L.; Diego, C.; Mayo, R.; Maestre, R. (2008) Use of supercritical fluid extraction and gas chromatography-mass spectrometry to obtain amino acid profiles from several genetically modified varieties of maize and soybean. J. Chromatogr. A, 1192 (2): 266 - 272.
146. Toribio, L.; Berbal, J.L.; Nozal, M.J.; Arnaiz, E.; Bernal, J. (2011) Sequential supercritical fluid extraction of lipids application to the obtention of the fatty acid profile of some genetically modified varieties of corn. Food Anal. Method., 4 (2): 196 - 202.
147. Ozkal, S.G.; Salgin, U.; Yener, M.E. (2005) Supercritical carbon dioxide extraction of hazelnut oil. J. Food Eng., 69 (2): 217 - 223.
148. Danielski, L.; Zetzl, C.; Hense, H.; Brunner, G. (2005) A process line for the production of raffinated rice oil from rice bran. J. Supercrit. Fluids, 34 (2): 133 - 141.
149. 2 and ethane. Fluid Phase Equilibr., (194-197): 885 - 894.
150. Saengcharoenrat, C.; Guyer, D.E. (2004) Effects of supercritical carbon dioxide conditions on onion oil desorption. J. Food Eng., 63 (1): 33 - 37.
151. 2 in packed bed extractor. J. Supercrit. Fluids, 28 (1): 11 - 19.
152. 2: Experiments and modeling. J. Supercrit. Fluids, 38 (3): 326 - 331.
153. 2 extraction of essential oil from orange peel; effect of the height of the bed. J. Supercrit. Fluids, 18 (3): 227 - 237.
154. 2. J. Supercrit. Fluids, 18 (1): 35 - 47.
155. 2. J. Supercrit. Fluids, 25 (1): 33 - 44.
156. 2. J. Supercrit. Fluids, 30 (2): 163 - 174.
157. Campos, L.M.A.S.; Leimann, F.V.; Pedrosa, R.C.; Ferreira, S.R.S. (2008) Free radical scavenging of grape pomace extracts from cabernet sauvingnon (Vitis vinifera). Bioresour. Technol., 99 (17): 8413 - 8420.
158. Passos, C.P.; Silva, R.M.; Silva, F.A.; Coimbra, M.A.; Silva, C.M. (2009) Enhancement of the supercritical fluid extraction of grape seed oil by using enzymatically pre-treated seed. J. Supercrit. Fluids, 48 (3): 225 - 229.
159. 2 extraction of Lycopene from tomato in the presence of vegetable oil as co-solvent. J. Supercrit. Fluids, 29 (1-2): 87 - 96.
160. 2 + ethanol) extraction of β-carotene from apricot pomace using response surface methodology. J. Supercrit. Fluids, 34 (3): 331 - 338.
161. Moore, S.; Samdani, S.; Ondrey, G.; Parkinson, G. (1994) New roles for supercritical. Chem. Eng., 32-35.
162. Kim, W.J.; Kim, J.D.; Kim, J.; Oh, S.G.; Lee, Y.W. (2008) Selective caffeine removal from green tea using supercritical carbon dioxide extraction. J. Food Eng., 89 (3): 303 - 309.
163. Sun, Q.L.; Shu, H.; Ye, J.H.; Lu, J.L.; Zheng, X.Q.; Liang, Y.R. (2010) Decaffeination of green tea by supercritical carbon dioxide. J. Med. Plant. Res., 4 (12): 1161 - 1168.
164. Perretti, G. (2006) Supercritical Carbon Dioxide Extraction of Agricultural and Food Processing Wastes and Byproducts. Mod. Ext. Tech. Am. Chem. Soc., 926 (2): 23 - 35.
165. De-Lucas, E.; Martínez, O.; Rincon, J.; Blanco, M.A.; Gracia, I. (2002) Supercritical fluid extraction of tocopherol concentrates from olive tree leaves. J. Supercrit. Fluids, 22 (3): 221 - 228.
166. Machmudah, S.; Winardi, S.; Sasaki, M.; Goto, M.; Kusumoto, N.; Hayakawa, K. (2012) Lycopene extraction from tomato peel by-product containing tomato seed using supercritical carbon dioxide. J. Food Eng., 108 (2): 290 - 296.
167. Klejdus, B.; Lojková, L.; Plaza, M.; Šnóblová, M.; Šterbová, D. (2010) Hyphenated technique for the extraction and determination of isoflavones in algae: Ultrasound-assisted supercritical fluid extraction followed by fast chromatography with tandem mass spectrometry. J. Chromatogr A, 1217 (51): 7956 - 7965.
168. Patil, P.D.; Gude, V.G.; Mannarswamy, A.; Deng, S.; Cooke, P.; Munson-Mcgee, S.; Rhodes, I.; Lammers, P.; Nirmalakhandan, N. (2011) Optimization of direct conversion of wet algae to biodiesel under supercritical methanol conditions. Bioresour. Technol., 102 (1): 118 - 122.
169. Pasquali, I. Bettini, R. (2008) Are pharmaceutics really going supercritical? International J. Pharmaceut., 364 (2): 176 - 187.
170. Lesoin, L.; Crampon, C. Boutin, O. Badens, E. (2011) Preparation of liposomes using the supercritical anti-solvent (SAS) process and comparison with a conventional method. J. Supercrit. Fluids, 57 (2): 162 - 174.
171. Sunarso, J.; Ismadji, S. (2009) Decontamination of hazardous substances from solid matrices and liquids using supercritical fluid extraction: A review. J. Hazard. Mater., 161 (1): 1 - 20.
172. Chen, C.H.; Chen, W.H.; Chang, C.M.J.; Lai, S.M.; Tu, C.H. (2010) Biodiesel production from supercritical carbon dioxide extracted Jatropha oil using subcritical hydrolysis and supercritical methylation. J. Supercrit. Fluids, 52 (2): 228 - 234.
173. Lim, S. Hoong, S.S.; Teong, L.K.; Bhatia, S. (2010) Supercritical fluid reactive extraction of Jatropha curcas L. seeds with methanol: A novel biodiesel production method. Bioresour. Technol., 101 (18): 7169 - 7172.
174. Breet, E.; Nortjé, Y.; Greuning, C. (2011) Supercritical carbon dioxide extracted oil from Jatropha curcas: Directive for the biodiesel industry? J. Supercrit. Fluids, 60: 38 - 44.
175. Lim, S.; Lee, K.T. (2011) Effects of solid pre-treatment towards optimizing supercritical methanol extraction and transesterification of Jatropha curcas L. seeds for the production of biodiesel. Sep. Purif. Technol., 81 (3): 363 - 370.
176. 2 as feedstock for biodiesel production. Biochem. Engn. J., 55 (1): 23 - 31.
177. 2 media. Biochem. Engn. J., 60 (15): 106 - 110.
178. Gui, M.M.; Lee, K.T.; Bhatia, S. (2009) Supercritical ethanol technology for the production of biodiesel: Process optimization studies. J. Supercrit. Fluids, 49 (2): 286 - 292.
179. 2: The effect of process conditions. J. Supercrit. Fluids, 51 (1): 67 - 73.
180. Arias, M.; Penichet, I.; Ysambertt, F.; Bauza, R.; Zougagh, M. Ríos, A. (2009) Fast supercritical fluid extraction of low- and high-density polyethylene additives: Comparison with conventional reflux and automatic Soxhlet extraction. J. Supercrit. Fluids, 50 (1): 22 - 28.
181. 2 in molten polymer. Pol. Eng. Sci., 44 (10): 1915 - 24.
182. Fujiwara, T.; Yamaoka, K.Y.; Wynne, K.J. (2005) Poly (lactide) swelling and melting behavior in supercritical carbon dioxide and post-venting porous material. Biomacromol., 6: 2370 - 3.
183. Furlan, M.; Kluge, J.; Mazzotti, M.; Lattuada, M. (2010) Preparation of biocompatible magnetite-PLGA composite nanoparticles using supercritical fluid extraction of emulsions. J. Supercrit. Fluids, 54 (3): 348 - 356.
184. 2 in the fabrication of polymer systems for drug delivery and tissue engineering. Adv. Drug Deliver. Rev., 60 (3): 373 - 387.
185. Rezaee, M.; Yamini, Y.; Moradi, M.; Saleh, A.; Faraji, M.; Naeeni, M.H. (2010) Supercritical fluid extraction combined with dispersive liquid-liquid microextraction as a sensitive and efficient sample preparation method for determination of organic compounds in solid samples. J. Supercrit. Fluids, 55: 161 - 168.
186. Naeeni, M.H.; Yamini, Y.; Rezaee, M. (2011) Combination of supercritical fluid extraction with dispersive liquid-liquid microextraction for extraction of organophosphorus pesticides from soil and marine sediment samples. J. Supercrit. Fluids, 57: 219 - 226.
187. Yang, T.J.; Tsai, F.J.; Chen, C.Y.; Yang, T.C.C.; Lee, M.R. (2010) Determination of additives in cosmetics by supercritical fluid extraction on-line headspace solid-phase microextraction combined with gas chromatography-mass spectrometry. Anal. Chim. Acta., 668: 188 - 194.
188. Klejdus, B.; Kopecky, J.; Benesová, L.; Vacek, J. (2009) Solid-phase/supercritical-fluid extraction for liquid chromatography of phenolic compounds in freshwater microalgae and selected cyanobacterial species. J. Chromatogr A, 1216: 763 - 771.
189. Melo, C.I.; Bogel-Łukasika, R.; Bogel-Łukasik, E. (2012) Combination of supercritical carbon dioxide and ionic liquid in a novel assembly of carvacrol. J. Supercrit. Fluids, 61: 191 - 198.
190. 2 extraction. Ultrason. Sonochem., 18: 318 - 326.
191. 2. J. Supercrit. Fluids, 44: 315 - 324.
192. Ortuño, C.; Martínez-Pastor, M.T.; Mulet, A.; Benedito, J. (2013) Application of high power ultrasound in the supercritical carbon dioxide inactivation of Saccharomyces cerevisiae. Food Res. Int., 51 (2): 474 - 481.
193. Ortuño, C.; Martínez-Pastor, M.T.; Mulet, A.; Benedito, J. (2012) An ultrasound-enhanced system for microbial inactivation using supercritical carbon dioxide. Innov. Food Sci. Emerg., 15: 31 - 37.
194. Adams, M.K. (1991) Analysis of coffee: production and trade. Allentown: Liquid Carbonic Industries Corporation, pp. 1-30.
195. Anklam, E.; Müller, A. (1995) Extraction of caffeine and vanillin from drugs by supercritical carbon dioxide. Pharmazie, 50 (1): 364 - 365.
196. Mcnally, M.E.P. (1996) Method development in supercritical fluid extraction. J. AOAC Inter., 79 (4): 380 - 387.