-
1
-
-
29444459408
-
Natural killer cells in human health and disease
-
Orange JS, Ballas ZK. Natural killer cells in human health and disease. Clin Immunol 2006;118:1-10.
-
(2006)
Clin Immunol
, vol.118
, pp. 1-10
-
-
Orange, J.S.1
Ballas, Z.K.2
-
3
-
-
0036931320
-
Human natural killer cell deficiencies and susceptibility to infection
-
Orange JS. Human natural killer cell deficiencies and susceptibility to infection. Microbes Infect 2002;4:1545-1558.
-
(2002)
Microbes Infect
, vol.4
, pp. 1545-1558
-
-
Orange, J.S.1
-
4
-
-
33750800121
-
Human natural killer cell deficiencies
-
Orange JS. Human natural killer cell deficiencies. Curr Opin Allergy Clin Immunol 2006;6:399-409.
-
(2006)
Curr Opin Allergy Clin Immunol
, vol.6
, pp. 399-409
-
-
Orange, J.S.1
-
5
-
-
0033593045
-
The human natural killer cell immune synapse
-
Davis DM, Chiu I, Fassett M, Cohen GB, Mandelboim O, Strominger JL. The human natural killer cell immune synapse. Proc Natl Acad Sci USA 1999;96:15062-15067.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 15062-15067
-
-
Davis, D.M.1
Chiu, I.2
Fassett, M.3
Cohen, G.B.4
Mandelboim, O.5
Strominger, J.L.6
-
6
-
-
50249184550
-
Formation and function of the lytic NK-cell immunological synapse
-
Orange JS. Formation and function of the lytic NK-cell immunological synapse. Nat Rev Immunol 2008;8:713-725.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 713-725
-
-
Orange, J.S.1
-
7
-
-
0036644617
-
Assembly of the immunological synapse for T cells and NK cells
-
Davis DM. Assembly of the immunological synapse for T cells and NK cells. Trends Immunol 2002;23:356-363.
-
(2002)
Trends Immunol
, vol.23
, pp. 356-363
-
-
Davis, D.M.1
-
8
-
-
9644275363
-
CTL secretory lysosomes: biogenesis and secretion of a harmful organelle
-
Bossi G, Griffiths GM. CTL secretory lysosomes: biogenesis and secretion of a harmful organelle. Semin Immunol 2005;17:87-94.
-
(2005)
Semin Immunol
, vol.17
, pp. 87-94
-
-
Bossi, G.1
Griffiths, G.M.2
-
10
-
-
0036779576
-
Functional significance of the perforin/granzyme cell death pathway
-
Trapani JA, Smyth MJ. Functional significance of the perforin/granzyme cell death pathway. Nat Rev Immunol 2002;2:735-747.
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 735-747
-
-
Trapani, J.A.1
Smyth, M.J.2
-
11
-
-
33344458030
-
T cells use two directionally distinct pathways for cytokine secretion
-
Huse M, Lillemeier BF, Kuhns MS, Chen DS, Davis MM. T cells use two directionally distinct pathways for cytokine secretion. Nat Immunol 2006;7:247-255.
-
(2006)
Nat Immunol
, vol.7
, pp. 247-255
-
-
Huse, M.1
Lillemeier, B.F.2
Kuhns, M.S.3
Chen, D.S.4
Davis, M.M.5
-
12
-
-
11144299492
-
NK cell recognition
-
Lanier LL. NK cell recognition. Annu Rev Immunol 2005;23:225-274.
-
(2005)
Annu Rev Immunol
, vol.23
, pp. 225-274
-
-
Lanier, L.L.1
-
13
-
-
9444249908
-
Natural killer cell signaling pathways
-
Vivier E, Nunes JA, Vely F. Natural killer cell signaling pathways. Science 2004;306:1517-1519.
-
(2004)
Science
, vol.306
, pp. 1517-1519
-
-
Vivier, E.1
Nunes, J.A.2
Vely, F.3
-
14
-
-
0033618504
-
Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA
-
Bauer S, et al. Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. Science 1999;285:727-729.
-
(1999)
Science
, vol.285
, pp. 727-729
-
-
Bauer, S.1
-
15
-
-
0034924218
-
Interactions of human NKG2D with its ligands MICA, MICB, and homologs of the mouse RAE-1 protein family
-
Steinle A, et al. Interactions of human NKG2D with its ligands MICA, MICB, and homologs of the mouse RAE-1 protein family. Immunogenetics 2001;53:279-287.
-
(2001)
Immunogenetics
, vol.53
, pp. 279-287
-
-
Steinle, A.1
-
16
-
-
0037108353
-
Cutting edge: murine UL16-binding protein-like transcript 1: a newly described transcript encoding a high-affinity ligand for murine NKG2D
-
Carayannopoulos LN, Naidenko OV, Fremont DH, Yokoyama WM. Cutting edge: murine UL16-binding protein-like transcript 1: a newly described transcript encoding a high-affinity ligand for murine NKG2D. J Immunol 2002;169:4079-4083.
-
(2002)
J Immunol
, vol.169
, pp. 4079-4083
-
-
Carayannopoulos, L.N.1
Naidenko, O.V.2
Fremont, D.H.3
Yokoyama, W.M.4
-
17
-
-
0035099068
-
ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor
-
Cosman D, et al. ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor. Immunity 2001;14:123-133.
-
(2001)
Immunity
, vol.14
, pp. 123-133
-
-
Cosman, D.1
-
18
-
-
0022332689
-
Functional properties of a unique subset of cytotoxic CD3+ T lymphocytes that express Fc receptors for IgG (CD16/Leu-11 antigen)
-
Lanier LL, Kipps TJ, Phillips JH. Functional properties of a unique subset of cytotoxic CD3+ T lymphocytes that express Fc receptors for IgG (CD16/Leu-11 antigen). J Exp Med 1985;162:2089-2106.
-
(1985)
J Exp Med
, vol.162
, pp. 2089-2106
-
-
Lanier, L.L.1
Kipps, T.J.2
Phillips, J.H.3
-
19
-
-
0035931861
-
Recognition of haemagglutinins on virus-infected cells by NKp46 activates lysis by human NK cells
-
Mandelboim O, et al. Recognition of haemagglutinins on virus-infected cells by NKp46 activates lysis by human NK cells. Nature 2001;409:1055-1060.
-
(2001)
Nature
, vol.409
, pp. 1055-1060
-
-
Mandelboim, O.1
-
20
-
-
0031898453
-
Fc receptors on natural killer cells
-
Perussia B. Fc receptors on natural killer cells. Curr Top Microbiol Immunol 1998;230:63-88.
-
(1998)
Curr Top Microbiol Immunol
, vol.230
, pp. 63-88
-
-
Perussia, B.1
-
21
-
-
0029003984
-
Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells
-
Colonna M, Samaridis J. Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells. Science 1995;268:405-408.
-
(1995)
Science
, vol.268
, pp. 405-408
-
-
Colonna, M.1
Samaridis, J.2
-
22
-
-
0029551048
-
Killer cell inhibitory receptors specific for HLA-C and HLA-B identified by direct binding and by functional transfer
-
Wagtmann N, Rajagopalan S, Winter CC, Peruzzi M, Long EO. Killer cell inhibitory receptors specific for HLA-C and HLA-B identified by direct binding and by functional transfer. Immunity 1995;3:801-809.
-
(1995)
Immunity
, vol.3
, pp. 801-809
-
-
Wagtmann, N.1
Rajagopalan, S.2
Winter, C.C.3
Peruzzi, M.4
Long, E.O.5
-
23
-
-
0032546001
-
HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C
-
Braud VM, et al. HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C. Nature 1998;391:795-799.
-
(1998)
Nature
, vol.391
, pp. 795-799
-
-
Braud, V.M.1
-
24
-
-
0032538916
-
Mouse CD94/NKG2A is a natural killer cell receptor for the nonclassical major histocompatibility complex (MHC) class I molecule Qa-1(b)
-
Vance RE, Kraft JR, Altman JD, Jensen PE, Raulet DH. Mouse CD94/NKG2A is a natural killer cell receptor for the nonclassical major histocompatibility complex (MHC) class I molecule Qa-1(b). J Exp Med 1998;188:1841-1848.
-
(1998)
J Exp Med
, vol.188
, pp. 1841-1848
-
-
Vance, R.E.1
Kraft, J.R.2
Altman, J.D.3
Jensen, P.E.4
Raulet, D.H.5
-
25
-
-
0033000015
-
A comparison of viral immune escape strategies targeting the MHC class I assembly pathway
-
Fruh K, Gruhler A, Krishna RM, Schoenhals GJ. A comparison of viral immune escape strategies targeting the MHC class I assembly pathway. Immunol Rev 1999;168:157-166.
-
(1999)
Immunol Rev
, vol.168
, pp. 157-166
-
-
Fruh, K.1
Gruhler, A.2
Krishna, R.M.3
Schoenhals, G.J.4
-
27
-
-
51149108034
-
The killer's kiss: the many functions of NK cell immunological synapses
-
Krzewski K, Strominger JL. The killer's kiss: the many functions of NK cell immunological synapses. Curr Opin Cell Biol 2008;20:597-605.
-
(2008)
Curr Opin Cell Biol
, vol.20
, pp. 597-605
-
-
Krzewski, K.1
Strominger, J.L.2
-
28
-
-
2342566929
-
What is the importance of the immunological synapse?
-
Davis DM, Dustin ML. What is the importance of the immunological synapse? Trends Immunol 2004;25:323-327.
-
(2004)
Trends Immunol
, vol.25
, pp. 323-327
-
-
Davis, D.M.1
Dustin, M.L.2
-
29
-
-
0033538574
-
The immunological synapse: a molecular machine controlling T cell activation
-
Grakoui A, et al. The immunological synapse: a molecular machine controlling T cell activation. Science 1999;285:221-227.
-
(1999)
Science
, vol.285
, pp. 221-227
-
-
Grakoui, A.1
-
30
-
-
0032480279
-
Three-dimensional segregation of supramolecular activation clusters in T cells
-
Monks CR, Freiberg BA, Kupfer H, Sciaky N, Kupfer A. Three-dimensional segregation of supramolecular activation clusters in T cells. Nature 1998;395:82-86.
-
(1998)
Nature
, vol.395
, pp. 82-86
-
-
Monks, C.R.1
Freiberg, B.A.2
Kupfer, H.3
Sciaky, N.4
Kupfer, A.5
-
31
-
-
0034714184
-
Differential clustering of CD4 and CD3zeta during T cell recognition
-
Krummel MF, Sjaastad MD, Wulfing C, Davis MM. Differential clustering of CD4 and CD3zeta during T cell recognition. Science 2000;289:1349-1352.
-
(2000)
Science
, vol.289
, pp. 1349-1352
-
-
Krummel, M.F.1
Sjaastad, M.D.2
Wulfing, C.3
Davis, M.M.4
-
32
-
-
0032545218
-
A receptor/cytoskeletal movement triggered by costimulation during T cell activation
-
Wulfing C, Davis MM. A receptor/cytoskeletal movement triggered by costimulation during T cell activation. Science 1998;282:2266-2269.
-
(1998)
Science
, vol.282
, pp. 2266-2269
-
-
Wulfing, C.1
Davis, M.M.2
-
33
-
-
0005448458
-
Polarity of T cell shape, motility, and sensitivity to antigen
-
Negulescu PA, Krasieva TB, Khan A, Kerschbaum HH, Cahalan MD. Polarity of T cell shape, motility, and sensitivity to antigen. Immunity 1996;4:421-430.
-
(1996)
Immunity
, vol.4
, pp. 421-430
-
-
Negulescu, P.A.1
Krasieva, T.B.2
Khan, A.3
Kerschbaum, H.H.4
Cahalan, M.D.5
-
34
-
-
0036858983
-
Differential expression and distribution of ezrin, radixin and moesin in human natural killer cells
-
Ramoni C, Luciani F, Spadaro F, Lugini L, Lozupone F, Fais S. Differential expression and distribution of ezrin, radixin and moesin in human natural killer cells. Eur J Immunol 2002;32:3059-3065.
-
(2002)
Eur J Immunol
, vol.32
, pp. 3059-3065
-
-
Ramoni, C.1
Luciani, F.2
Spadaro, F.3
Lugini, L.4
Lozupone, F.5
Fais, S.6
-
35
-
-
0030847406
-
Moesin interacts with the cytoplasmic region of intercellular adhesion molecule-3 and is redistributed to the uropod of T lymphocytes during cell polarization
-
Serrador JM, et al. Moesin interacts with the cytoplasmic region of intercellular adhesion molecule-3 and is redistributed to the uropod of T lymphocytes during cell polarization. J Cell Biol 1997;138:1409-1423.
-
(1997)
J Cell Biol
, vol.138
, pp. 1409-1423
-
-
Serrador, J.M.1
-
36
-
-
0032193205
-
Roles of chemokines and receptor polarization in NK-target cell interactions
-
Nieto M, et al. Roles of chemokines and receptor polarization in NK-target cell interactions. J Immunol 1998;161:3330-3339.
-
(1998)
J Immunol
, vol.161
, pp. 3330-3339
-
-
Nieto, M.1
-
37
-
-
33751347857
-
The Scribble and Par complexes in polarity and migration: friends or foes?
-
Humbert PO, Dow LE, Russell SM. The Scribble and Par complexes in polarity and migration: friends or foes? Trends Cell Biol 2006;16:622-630.
-
(2006)
Trends Cell Biol
, vol.16
, pp. 622-630
-
-
Humbert, P.O.1
Dow, L.E.2
Russell, S.M.3
-
38
-
-
39849097037
-
Polarity complex proteins
-
Assemat E, Bazellieres E, Pallesi-Pocachard E, Le Bivic A, Massey-Harroche D. Polarity complex proteins. Biochim Biophys Acta 2008;1778:614-630.
-
(2008)
Biochim Biophys Acta
, vol.1778
, pp. 614-630
-
-
Assemat, E.1
Bazellieres, E.2
Pallesi-Pocachard, E.3
Le Bivic, A.4
Massey-Harroche, D.5
-
39
-
-
20444445916
-
A network of PDZ-containing proteins regulates T cell polarity and morphology during migration and immunological synapse formation
-
Ludford-Menting MJ, et al. A network of PDZ-containing proteins regulates T cell polarity and morphology during migration and immunological synapse formation. Immunity 2005;22:737-748.
-
(2005)
Immunity
, vol.22
, pp. 737-748
-
-
Ludford-Menting, M.J.1
-
40
-
-
4043099715
-
The LFA-1-associated molecule PTA-1 (CD226) on T cells forms a dynamic molecular complex with protein 4.1G and human discs large
-
Ralston KJ, et al. The LFA-1-associated molecule PTA-1 (CD226) on T cells forms a dynamic molecular complex with protein 4.1G and human discs large. J Biol Chem 2004;279:33816-33828.
-
(2004)
J Biol Chem
, vol.279
, pp. 33816-33828
-
-
Ralston, K.J.1
-
41
-
-
13644268540
-
Dlgh1 coordinates actin polymerization, synaptic T cell receptor and lipid raft aggregation, and effector function in T cells
-
Round JL, Tomassian T, Zhang M, Patel V, Schoenberger SP, Miceli MC. Dlgh1 coordinates actin polymerization, synaptic T cell receptor and lipid raft aggregation, and effector function in T cells. J Exp Med 2005;201:419-430.
-
(2005)
J Exp Med
, vol.201
, pp. 419-430
-
-
Round, J.L.1
Tomassian, T.2
Zhang, M.3
Patel, V.4
Schoenberger, S.P.5
Miceli, M.C.6
-
42
-
-
78049354941
-
Tethering of intercellular adhesion molecule on target cells is required for LFA-1-dependent NK cell adhesion and granule polarization
-
Gross CC, Brzostowski JA, Liu D, Long EO. Tethering of intercellular adhesion molecule on target cells is required for LFA-1-dependent NK cell adhesion and granule polarization. J Immunol 2010;185:2918-2926.
-
(2010)
J Immunol
, vol.185
, pp. 2918-2926
-
-
Gross, C.C.1
Brzostowski, J.A.2
Liu, D.3
Long, E.O.4
-
43
-
-
0029945112
-
ICAM-2 redistributed by ezrin as a target for killer cells
-
Helander TS, Carpen O, Turunen O, Kovanen PE, Vaheri A, Timonen T. ICAM-2 redistributed by ezrin as a target for killer cells. Nature 1996;382:265-268.
-
(1996)
Nature
, vol.382
, pp. 265-268
-
-
Helander, T.S.1
Carpen, O.2
Turunen, O.3
Kovanen, P.E.4
Vaheri, A.5
Timonen, T.6
-
44
-
-
84881073251
-
Rituximab causes a polarisation of B cells which augments its therapeutic function in NK cell-mediated antibody-dependent cellular cytotoxicity
-
Rudnicka D, et al. Rituximab causes a polarisation of B cells which augments its therapeutic function in NK cell-mediated antibody-dependent cellular cytotoxicity. Blood 2013;121:4694-4702.
-
(2013)
Blood
, vol.121
, pp. 4694-4702
-
-
Rudnicka, D.1
-
45
-
-
33947730608
-
Asymmetric T lymphocyte division in the initiation of adaptive immune responses
-
Chang JT, et al. Asymmetric T lymphocyte division in the initiation of adaptive immune responses. Science 2007;315:1687-1691.
-
(2007)
Science
, vol.315
, pp. 1687-1691
-
-
Chang, J.T.1
-
46
-
-
77956201049
-
Asymmetric cell division of T cells upon antigen presentation uses multiple conserved mechanisms
-
Oliaro J, et al. Asymmetric cell division of T cells upon antigen presentation uses multiple conserved mechanisms. J Immunol 2010;185:367-375.
-
(2010)
J Immunol
, vol.185
, pp. 367-375
-
-
Oliaro, J.1
-
47
-
-
84867814099
-
T cell affinity regulates asymmetric division, effector cell differentiation, and tissue pathology
-
King CG, Koehli S, Hausmann B, Schmaler M, Zehn D, Palmer E. T cell affinity regulates asymmetric division, effector cell differentiation, and tissue pathology. Immunity 2012;37:709-720.
-
(2012)
Immunity
, vol.37
, pp. 709-720
-
-
King, C.G.1
Koehli, S.2
Hausmann, B.3
Schmaler, M.4
Zehn, D.5
Palmer, E.6
-
48
-
-
84856071457
-
Asymmetric B cell division in the germinal center reaction
-
Barnett BE, et al. Asymmetric B cell division in the germinal center reaction. Science 2012;335:342-344.
-
(2012)
Science
, vol.335
, pp. 342-344
-
-
Barnett, B.E.1
-
49
-
-
84856250820
-
Asymmetric segregation of polarized antigen on B cell division shapes presentation capacity
-
Thaunat O, et al. Asymmetric segregation of polarized antigen on B cell division shapes presentation capacity. Science 2012;335:475-479.
-
(2012)
Science
, vol.335
, pp. 475-479
-
-
Thaunat, O.1
-
50
-
-
0034774942
-
Specific and nonspecific NK cell activation during virus infection
-
Dokun AO, Kim S, Smith HR, Kang HS, Chu DT, Yokoyama WM. Specific and nonspecific NK cell activation during virus infection. Nat Immunol 2001;2:951-956.
-
(2001)
Nat Immunol
, vol.2
, pp. 951-956
-
-
Dokun, A.O.1
Kim, S.2
Smith, H.R.3
Kang, H.S.4
Chu, D.T.5
Yokoyama, W.M.6
-
51
-
-
77953741707
-
Immune memory redefined: characterizing the longevity of natural killer cells
-
Sun JC, Beilke JN, Lanier LL. Immune memory redefined: characterizing the longevity of natural killer cells. Immunol Rev 2010;236:83-94.
-
(2010)
Immunol Rev
, vol.236
, pp. 83-94
-
-
Sun, J.C.1
Beilke, J.N.2
Lanier, L.L.3
-
52
-
-
33645989497
-
T cell- and B cell-independent adaptive immunity mediated by natural killer cells
-
O'Leary JG, Goodarzi M, Drayton DL, von Andrian UH. T cell- and B cell-independent adaptive immunity mediated by natural killer cells. Nat Immunol 2006;7:507-516.
-
(2006)
Nat Immunol
, vol.7
, pp. 507-516
-
-
O'Leary, J.G.1
Goodarzi, M.2
Drayton, D.L.3
von Andrian, U.H.4
-
53
-
-
0035887645
-
Spatial organization of signal transduction molecules in the NK cell immune synapses during MHC class I-regulated noncytolytic and cytolytic interactions
-
Vyas YM, et al. Spatial organization of signal transduction molecules in the NK cell immune synapses during MHC class I-regulated noncytolytic and cytolytic interactions. J Immunol 2001;167:4358-4367.
-
(2001)
J Immunol
, vol.167
, pp. 4358-4367
-
-
Vyas, Y.M.1
-
54
-
-
79957621253
-
The insider's guide to leukocyte integrin signalling and function
-
Hogg N, Patzak I, Willenbrock F. The insider's guide to leukocyte integrin signalling and function. Nat Rev Immunol 2011;11:416-426.
-
(2011)
Nat Rev Immunol
, vol.11
, pp. 416-426
-
-
Hogg, N.1
Patzak, I.2
Willenbrock, F.3
-
55
-
-
84857688656
-
Integrin inside-out signaling and the immunological synapse
-
Springer TA, Dustin ML. Integrin inside-out signaling and the immunological synapse. Curr Opin Cell Biol 2012;24:107-115.
-
(2012)
Curr Opin Cell Biol
, vol.24
, pp. 107-115
-
-
Springer, T.A.1
Dustin, M.L.2
-
56
-
-
70350497327
-
Minimal requirement for induction of natural cytotoxicity and intersection of activation signals by inhibitory receptors
-
Bryceson YT, Ljunggren HG, Long EO. Minimal requirement for induction of natural cytotoxicity and intersection of activation signals by inhibitory receptors. Blood 2009;114:2657-2666.
-
(2009)
Blood
, vol.114
, pp. 2657-2666
-
-
Bryceson, Y.T.1
Ljunggren, H.G.2
Long, E.O.3
-
57
-
-
79952774803
-
2B4 engagement mediates rapid LFA-1 and actin-dependent NK cell adhesion to tumor cells as measured by single cell force spectroscopy
-
Hoffmann SC, Cohnen A, Ludwig T, Watzl C. 2B4 engagement mediates rapid LFA-1 and actin-dependent NK cell adhesion to tumor cells as measured by single cell force spectroscopy. J Immunol 2011;186:2757-2764.
-
(2011)
J Immunol
, vol.186
, pp. 2757-2764
-
-
Hoffmann, S.C.1
Cohnen, A.2
Ludwig, T.3
Watzl, C.4
-
58
-
-
33846503506
-
Activating Ly-49 receptors regulate LFA-1-mediated adhesion by NK cells
-
Osman MS, Burshtyn DN, Kane KP. Activating Ly-49 receptors regulate LFA-1-mediated adhesion by NK cells. J Immunol 2007;178:1261-1267.
-
(2007)
J Immunol
, vol.178
, pp. 1261-1267
-
-
Osman, M.S.1
Burshtyn, D.N.2
Kane, K.P.3
-
59
-
-
0037218654
-
Coexpression of CD58 or CD48 with intercellular adhesion molecule 1 on target cells enhances adhesion of resting NK cells
-
Barber DF, Long EO. Coexpression of CD58 or CD48 with intercellular adhesion molecule 1 on target cells enhances adhesion of resting NK cells. J Immunol 2003;170:294-299.
-
(2003)
J Immunol
, vol.170
, pp. 294-299
-
-
Barber, D.F.1
Long, E.O.2
-
60
-
-
0042681786
-
Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins
-
Kim M, Carman CV, Springer TA. Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins. Science 2003;301:1720-1725.
-
(2003)
Science
, vol.301
, pp. 1720-1725
-
-
Kim, M.1
Carman, C.V.2
Springer, T.A.3
-
61
-
-
33845566257
-
Importance of force linkage in mechanochemistry of adhesion receptors
-
Astrof NS, Salas A, Shimaoka M, Chen J, Springer TA. Importance of force linkage in mechanochemistry of adhesion receptors. Biochemistry 2006;45:15020-15028.
-
(2006)
Biochemistry
, vol.45
, pp. 15020-15028
-
-
Astrof, N.S.1
Salas, A.2
Shimaoka, M.3
Chen, J.4
Springer, T.A.5
-
62
-
-
68049118970
-
Natural killer cell signal integration balances synapse symmetry and migration
-
Culley FJ, et al. Natural killer cell signal integration balances synapse symmetry and migration. PLoS Biol 2009;7:e1000159.
-
(2009)
PLoS Biol
, vol.7
-
-
Culley, F.J.1
-
63
-
-
33646454106
-
B cell ligand discrimination through a spreading and contraction response
-
Fleire SJ, Goldman JP, Carrasco YR, Weber M, Bray D, Batista FD. B cell ligand discrimination through a spreading and contraction response. Science 2006;312:738-741.
-
(2006)
Science
, vol.312
, pp. 738-741
-
-
Fleire, S.J.1
Goldman, J.P.2
Carrasco, Y.R.3
Weber, M.4
Bray, D.5
Batista, F.D.6
-
64
-
-
42249090333
-
Phospholipase C-gamma2 and Vav cooperate within signaling microclusters to propagate B cell spreading in response to membrane-bound antigen
-
Weber M, et al. Phospholipase C-gamma2 and Vav cooperate within signaling microclusters to propagate B cell spreading in response to membrane-bound antigen. J Exp Med 2008;205:853-868.
-
(2008)
J Exp Med
, vol.205
, pp. 853-868
-
-
Weber, M.1
-
65
-
-
79951911283
-
Inhibitory signaling blocks activating receptor clustering and induces cytoskeletal retraction in natural killer cells
-
Abeyweera TP, Merino E, Huse M. Inhibitory signaling blocks activating receptor clustering and induces cytoskeletal retraction in natural killer cells. J Cell Biol 2011;192:675-690.
-
(2011)
J Cell Biol
, vol.192
, pp. 675-690
-
-
Abeyweera, T.P.1
Merino, E.2
Huse, M.3
-
66
-
-
3242767507
-
Cutting edge: membrane nanotubes connect immune cells
-
Onfelt B, Nedvetzki S, Yanagi K, Davis DM. Cutting edge: membrane nanotubes connect immune cells. J Immunol 2004;173:1511-1513.
-
(2004)
J Immunol
, vol.173
, pp. 1511-1513
-
-
Onfelt, B.1
Nedvetzki, S.2
Yanagi, K.3
Davis, D.M.4
-
67
-
-
44349098785
-
Membrane nanotubes: dynamic long-distance connections between animal cells
-
Davis DM, Sowinski S. Membrane nanotubes: dynamic long-distance connections between animal cells. Nat Rev Mol Cell Biol 2008;9:431-436.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 431-436
-
-
Davis, D.M.1
Sowinski, S.2
-
68
-
-
77950398569
-
Membrane nanotubes facilitate long-distance interactions between natural killer cells and target cells
-
Chauveau A, Aucher A, Eissmann P, Vivier E, Davis DM. Membrane nanotubes facilitate long-distance interactions between natural killer cells and target cells. Proc Natl Acad Sci USA 2010;107:5545-5550.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 5545-5550
-
-
Chauveau, A.1
Aucher, A.2
Eissmann, P.3
Vivier, E.4
Davis, D.M.5
-
69
-
-
33845421625
-
Structurally distinct membrane nanotubes between human macrophages support long-distance vesicular traffic or surfing of bacteria
-
Onfelt B, et al. Structurally distinct membrane nanotubes between human macrophages support long-distance vesicular traffic or surfing of bacteria. J Immunol 2006;177:8476-8483.
-
(2006)
J Immunol
, vol.177
, pp. 8476-8483
-
-
Onfelt, B.1
-
70
-
-
84872137228
-
Membrane nanotubes in myeloid cells in the adult mouse cornea represent a novel mode of immune cell interaction
-
Seyed-Razavi Y, Hickey MJ, Kuffova L, McMenamin PG, Chinnery HR. Membrane nanotubes in myeloid cells in the adult mouse cornea represent a novel mode of immune cell interaction. Immunol Cell Biol 2013;91:89-95.
-
(2013)
Immunol Cell Biol
, vol.91
, pp. 89-95
-
-
Seyed-Razavi, Y.1
Hickey, M.J.2
Kuffova, L.3
McMenamin, P.G.4
Chinnery, H.R.5
-
71
-
-
44449108230
-
Cutting edge: membrane nanotubes in vivo: a feature of MHC class II+ cells in the mouse cornea
-
Chinnery HR, Pearlman E, McMenamin PG. Cutting edge: membrane nanotubes in vivo: a feature of MHC class II+ cells in the mouse cornea. J Immunol 2008;180:5779-5783.
-
(2008)
J Immunol
, vol.180
, pp. 5779-5783
-
-
Chinnery, H.R.1
Pearlman, E.2
McMenamin, P.G.3
-
72
-
-
67650288199
-
Biochemical and structural properties of the integrin-associated cytoskeletal protein talin
-
Critchley DR. Biochemical and structural properties of the integrin-associated cytoskeletal protein talin. Annu Rev Biophys 2009;38:235-254.
-
(2009)
Annu Rev Biophys
, vol.38
, pp. 235-254
-
-
Critchley, D.R.1
-
73
-
-
60549106555
-
A dual role for talin in NK cell cytotoxicity: activation of LFA-1-mediated cell adhesion and polarization of NK cells
-
Mace EM, Monkley SJ, Critchley DR, Takei F. A dual role for talin in NK cell cytotoxicity: activation of LFA-1-mediated cell adhesion and polarization of NK cells. J Immunol 2009;182:948-956.
-
(2009)
J Immunol
, vol.182
, pp. 948-956
-
-
Mace, E.M.1
Monkley, S.J.2
Critchley, D.R.3
Takei, F.4
-
74
-
-
83755196111
-
Contact-dependent T cell activation and T cell stopping require Talin1
-
Wernimont SA, et al. Contact-dependent T cell activation and T cell stopping require Talin1. J Immunol 2011;187:6256-6267.
-
(2011)
J Immunol
, vol.187
, pp. 6256-6267
-
-
Wernimont, S.A.1
-
75
-
-
10544241952
-
Talin contains three actin-binding sites each of which is adjacent to a vinculin-binding site
-
Hemmings L, et al. Talin contains three actin-binding sites each of which is adjacent to a vinculin-binding site. J Cell Sci 1996;109:2715-2726.
-
(1996)
J Cell Sci
, vol.109
, pp. 2715-2726
-
-
Hemmings, L.1
-
76
-
-
79151482119
-
Vinculin, an adapter protein in control of cell adhesion signalling
-
Carisey A, Ballestrem C. Vinculin, an adapter protein in control of cell adhesion signalling. Eur J Cell Biol 2011;90:157-163.
-
(2011)
Eur J Cell Biol
, vol.90
, pp. 157-163
-
-
Carisey, A.1
Ballestrem, C.2
-
77
-
-
77956535011
-
Elucidation of the integrin LFA-1-mediated signaling pathway of actin polarization in natural killer cells
-
Mace EM, Zhang JY, Siminovitch KA, Takei F. Elucidation of the integrin LFA-1-mediated signaling pathway of actin polarization in natural killer cells. Blood 2010;116:1272-1279.
-
(2010)
Blood
, vol.116
, pp. 1272-1279
-
-
Mace, E.M.1
Zhang, J.Y.2
Siminovitch, K.A.3
Takei, F.4
-
78
-
-
0037143734
-
Wiskott-Aldrich syndrome protein is required for NK cell cytotoxicity and colocalizes with actin to NK cell-activating immunologic synapses
-
Orange JS, et al. Wiskott-Aldrich syndrome protein is required for NK cell cytotoxicity and colocalizes with actin to NK cell-activating immunologic synapses. Proc Natl Acad Sci USA 2002;99:11351-11356.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 11351-11356
-
-
Orange, J.S.1
-
79
-
-
84875454223
-
Dedicator of cytokinesis 8 interacts with talin and Wiskott-Aldrich syndrome protein to regulate NK cell cytotoxicity
-
Ham H, et al. Dedicator of cytokinesis 8 interacts with talin and Wiskott-Aldrich syndrome protein to regulate NK cell cytotoxicity. J Immunol 2013;190:3661-3669.
-
(2013)
J Immunol
, vol.190
, pp. 3661-3669
-
-
Ham, H.1
-
80
-
-
0032559362
-
Rho GTPases and the actin cytoskeleton
-
Hall A. Rho GTPases and the actin cytoskeleton. Science 1998;279:509-514.
-
(1998)
Science
, vol.279
, pp. 509-514
-
-
Hall, A.1
-
81
-
-
61949352480
-
Kindlin-3 is required for beta2 integrin-mediated leukocyte adhesion to endothelial cells
-
Moser M, et al. Kindlin-3 is required for beta2 integrin-mediated leukocyte adhesion to endothelial cells. Nat Med 2009;15:300-305.
-
(2009)
Nat Med
, vol.15
, pp. 300-305
-
-
Moser, M.1
-
82
-
-
66449119343
-
Kindlin-1 and -2 directly bind the C-terminal region of beta integrin cytoplasmic tails and exert integrin-specific activation effects
-
Harburger DS, Bouaouina M, Calderwood DA. Kindlin-1 and -2 directly bind the C-terminal region of beta integrin cytoplasmic tails and exert integrin-specific activation effects. J Biol Chem 2009;284:11485-11497.
-
(2009)
J Biol Chem
, vol.284
, pp. 11485-11497
-
-
Harburger, D.S.1
Bouaouina, M.2
Calderwood, D.A.3
-
83
-
-
70349312643
-
The Kindlin protein family: new members to the club of focal adhesion proteins
-
Meves A, Stremmel C, Gottschalk K, Fässler R. The Kindlin protein family: new members to the club of focal adhesion proteins. Trends Cell Biol 2009;19:504-513.
-
(2009)
Trends Cell Biol
, vol.19
, pp. 504-513
-
-
Meves, A.1
Stremmel, C.2
Gottschalk, K.3
Fässler, R.4
-
84
-
-
70349565999
-
Loss of Kindlin-3 in LAD-III eliminates LFA-1 but not VLA-4 adhesiveness developed under shear flow conditions
-
Manevich-Mendelson E, et al. Loss of Kindlin-3 in LAD-III eliminates LFA-1 but not VLA-4 adhesiveness developed under shear flow conditions. Blood 2009;114:2344-2353.
-
(2009)
Blood
, vol.114
, pp. 2344-2353
-
-
Manevich-Mendelson, E.1
-
85
-
-
79959858924
-
Kindlin-3 is required for the stabilization of TCR-stimulated LFA-1:ICAM-1 bonds critical for lymphocyte arrest and spreading on dendritic cells
-
Feigelson SW, et al. Kindlin-3 is required for the stabilization of TCR-stimulated LFA-1:ICAM-1 bonds critical for lymphocyte arrest and spreading on dendritic cells. Blood 2011;117:7042-7052.
-
(2011)
Blood
, vol.117
, pp. 7042-7052
-
-
Feigelson, S.W.1
-
86
-
-
84868608902
-
Loss of kindlin-3 alters the threshold for NK cell activation in human leukocyte adhesion deficiency-III
-
Gruda R, et al. Loss of kindlin-3 alters the threshold for NK cell activation in human leukocyte adhesion deficiency-III. Blood 2012;120:3915-3924.
-
(2012)
Blood
, vol.120
, pp. 3915-3924
-
-
Gruda, R.1
-
87
-
-
0037144842
-
T cell receptor ligation induces the formation of dynamically regulated signaling assemblies
-
Bunnell SC, et al. T cell receptor ligation induces the formation of dynamically regulated signaling assemblies. J Cell Biol 2002;158:1263-1275.
-
(2002)
J Cell Biol
, vol.158
, pp. 1263-1275
-
-
Bunnell, S.C.1
-
88
-
-
27544441784
-
Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling
-
Campi G, Varma R, Dustin ML. Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling. J Exp Med 2005;202:1031-1036.
-
(2005)
J Exp Med
, vol.202
, pp. 1031-1036
-
-
Campi, G.1
Varma, R.2
Dustin, M.L.3
-
89
-
-
37349077033
-
CD19 is essential for B cell activation by promoting B cell receptor-antigen microcluster formation in response to membrane-bound ligand
-
Depoil D, et al. CD19 is essential for B cell activation by promoting B cell receptor-antigen microcluster formation in response to membrane-bound ligand. Nat Immunol 2008;9:63-72.
-
(2008)
Nat Immunol
, vol.9
, pp. 63-72
-
-
Depoil, D.1
-
90
-
-
68249149660
-
Integrin-dependent organization and bidirectional vesicular traffic at cytotoxic immune synapses
-
Liu D, Bryceson YT, Meckel T, Vasiliver-Shamis G, Dustin ML, Long EO. Integrin-dependent organization and bidirectional vesicular traffic at cytotoxic immune synapses. Immunity 2009;31:99-109.
-
(2009)
Immunity
, vol.31
, pp. 99-109
-
-
Liu, D.1
Bryceson, Y.T.2
Meckel, T.3
Vasiliver-Shamis, G.4
Dustin, M.L.5
Long, E.O.6
-
91
-
-
33746011209
-
T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster
-
Varma R, Campi G, Yokosuka T, Saito T, Dustin ML. T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster. Immunity 2006;25:117-127.
-
(2006)
Immunity
, vol.25
, pp. 117-127
-
-
Varma, R.1
Campi, G.2
Yokosuka, T.3
Saito, T.4
Dustin, M.L.5
-
92
-
-
38049136514
-
Mechanisms for segregating T cell receptor and adhesion molecules during immunological synapse formation in Jurkat T cells
-
Kaizuka Y, Douglass AD, Varma R, Dustin ML, Vale RD. Mechanisms for segregating T cell receptor and adhesion molecules during immunological synapse formation in Jurkat T cells. Proc Natl Acad Sci USA 2007;104:20296-20301.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 20296-20301
-
-
Kaizuka, Y.1
Douglass, A.D.2
Varma, R.3
Dustin, M.L.4
Vale, R.D.5
-
93
-
-
79956106702
-
Dynamic cortical actin remodeling by ERM proteins controls BCR microcluster organization and integrity
-
Treanor B, Depoil D, Bruckbauer A, Batista FD. Dynamic cortical actin remodeling by ERM proteins controls BCR microcluster organization and integrity. J Exp Med 2011;208:1055-1068.
-
(2011)
J Exp Med
, vol.208
, pp. 1055-1068
-
-
Treanor, B.1
Depoil, D.2
Bruckbauer, A.3
Batista, F.D.4
-
94
-
-
80053325995
-
Remodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopy
-
Brown AC, et al. Remodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopy. PLoS Biol 2011;9:e1001152.
-
(2011)
PLoS Biol
, vol.9
-
-
Brown, A.C.1
-
95
-
-
84860007628
-
The adaptor protein Crk controls activation and inhibition of natural killer cells
-
Liu D, Peterson ME, Long EO. The adaptor protein Crk controls activation and inhibition of natural killer cells. Immunity 2012;36:600-611.
-
(2012)
Immunity
, vol.36
, pp. 600-611
-
-
Liu, D.1
Peterson, M.E.2
Long, E.O.3
-
96
-
-
34247552223
-
Inhibitory receptor signals suppress ligation-induced recruitment of NKG2D to GM1-Rich membrane domains at the human NK cell immune synapse
-
Endt J, et al. Inhibitory receptor signals suppress ligation-induced recruitment of NKG2D to GM1-Rich membrane domains at the human NK cell immune synapse. J Immunol 2007;178:5606-5611.
-
(2007)
J Immunol
, vol.178
, pp. 5606-5611
-
-
Endt, J.1
-
97
-
-
23944469458
-
Coexistence of multivalent and monovalent TCRs explains high sensitivity and wide range of response
-
Schamel WW, et al. Coexistence of multivalent and monovalent TCRs explains high sensitivity and wide range of response. J Exp Med 2005;202:493-503.
-
(2005)
J Exp Med
, vol.202
, pp. 493-503
-
-
Schamel, W.W.1
-
98
-
-
74049157769
-
TCR and Lat are expressed on separate protein islands on T cell membranes and concatenate during activation
-
Lillemeier BF, Mortelmaier MA, Forstner MB, Huppa JB, Groves JT, Davis MM. TCR and Lat are expressed on separate protein islands on T cell membranes and concatenate during activation. Nat Immunol 2010;11:90-96.
-
(2010)
Nat Immunol
, vol.11
, pp. 90-96
-
-
Lillemeier, B.F.1
Mortelmaier, M.A.2
Forstner, M.B.3
Huppa, J.B.4
Groves, J.T.5
Davis, M.M.6
-
99
-
-
81955164142
-
Functional nanoscale organization of signaling molecules downstream of the T cell antigen receptor
-
Sherman E, et al. Functional nanoscale organization of signaling molecules downstream of the T cell antigen receptor. Immunity 2011;35:705-720.
-
(2011)
Immunity
, vol.35
, pp. 705-720
-
-
Sherman, E.1
-
100
-
-
84880909774
-
Super-resolution microscopy reveals nanometre-scale reorganisation of inhibitory NK cell receptors upon activation via NKG2D
-
Pageon SV, Cordoba S, Owen DM, Rothery SM, Oszmiana A, Davis DM. Super-resolution microscopy reveals nanometre-scale reorganisation of inhibitory NK cell receptors upon activation via NKG2D. Sci Signal 2013;6:ra62.
-
(2013)
Sci Signal
, vol.6
-
-
Pageon, S.V.1
Cordoba, S.2
Owen, D.M.3
Rothery, S.M.4
Oszmiana, A.5
Davis, D.M.6
-
101
-
-
79953840956
-
Confinement of activating receptors at the plasma membrane controls natural killer cell tolerance
-
Guia S, et al. Confinement of activating receptors at the plasma membrane controls natural killer cell tolerance. Sci Signal 2011;4:ra21.
-
(2011)
Sci Signal
, vol.4
-
-
Guia, S.1
-
102
-
-
0023788823
-
Lipid sorting in epithelial cells
-
Simons K, van Meer G. Lipid sorting in epithelial cells. Biochemistry 1988;27:6197-6202.
-
(1988)
Biochemistry
, vol.27
, pp. 6197-6202
-
-
Simons, K.1
van Meer, G.2
-
104
-
-
9644284452
-
Single-molecule tracking of membrane molecules: plasma membrane compartmentalization and dynamic assembly of raft-philic signaling molecules
-
Kusumi A, Ike H, Nakada C, Murase K, Fujiwara T. Single-molecule tracking of membrane molecules: plasma membrane compartmentalization and dynamic assembly of raft-philic signaling molecules. Semin Immunol 2005;17:3-21.
-
(2005)
Semin Immunol
, vol.17
, pp. 3-21
-
-
Kusumi, A.1
Ike, H.2
Nakada, C.3
Murase, K.4
Fujiwara, T.5
-
105
-
-
34247861082
-
Plasma membrane-associated proteins are clustered into islands attached to the cytoskeleton
-
Lillemeier BF, Pfeiffer JR, Surviladze Z, Wilson BS, Davis MM. Plasma membrane-associated proteins are clustered into islands attached to the cytoskeleton. Proc Natl Acad Sci USA 2006;103:18992-18997.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 18992-18997
-
-
Lillemeier, B.F.1
Pfeiffer, J.R.2
Surviladze, Z.3
Wilson, B.S.4
Davis, M.M.5
-
106
-
-
0030949124
-
Functional rafts in cell membranes
-
Simons K, Ikonen E. Functional rafts in cell membranes. Nature 1997;387:569-572.
-
(1997)
Nature
, vol.387
, pp. 569-572
-
-
Simons, K.1
Ikonen, E.2
-
107
-
-
78650664669
-
Palmitoylation regulates raft affinity for the majority of integral raft proteins
-
Levental I, Lingwood D, Grzybek M, Coskun U, Simons K. Palmitoylation regulates raft affinity for the majority of integral raft proteins. Proc Natl Acad Sci USA 2010;107:22050-22054.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 22050-22054
-
-
Levental, I.1
Lingwood, D.2
Grzybek, M.3
Coskun, U.4
Simons, K.5
-
108
-
-
0037869152
-
T cell glycolipid-enriched membrane domains are constitutively assembled as membrane patches that translocate to immune synapses
-
Jordan S, Rodgers W. T cell glycolipid-enriched membrane domains are constitutively assembled as membrane patches that translocate to immune synapses. J Immunol 2003;171:78-87.
-
(2003)
J Immunol
, vol.171
, pp. 78-87
-
-
Jordan, S.1
Rodgers, W.2
-
109
-
-
33744494534
-
Quantitative proteomic analysis of B cell lipid rafts reveals that ezrin regulates antigen receptor-mediated lipid raft dynamics
-
Gupta N, Wollscheid B, Watts JD, Scheer B, Aebersold R, DeFranco AL. Quantitative proteomic analysis of B cell lipid rafts reveals that ezrin regulates antigen receptor-mediated lipid raft dynamics. Nat Immunol 2006;7:625-633.
-
(2006)
Nat Immunol
, vol.7
, pp. 625-633
-
-
Gupta, N.1
Wollscheid, B.2
Watts, J.D.3
Scheer, B.4
Aebersold, R.5
DeFranco, A.L.6
-
110
-
-
0037054546
-
Phospholipids undergo hop diffusion in compartmentalized cell membrane
-
Fujiwara T, Ritchie K, Murakoshi H, Jacobson K, Kusumi A. Phospholipids undergo hop diffusion in compartmentalized cell membrane. J Cell Biol 2002;157:1071-1081.
-
(2002)
J Cell Biol
, vol.157
, pp. 1071-1081
-
-
Fujiwara, T.1
Ritchie, K.2
Murakoshi, H.3
Jacobson, K.4
Kusumi, A.5
-
111
-
-
2942662120
-
Ultrafine membrane compartments for molecular diffusion as revealed by single molecule techniques
-
Murase K, et al. Ultrafine membrane compartments for molecular diffusion as revealed by single molecule techniques. Biophys J 2004;86:4075-4093.
-
(2004)
Biophys J
, vol.86
, pp. 4075-4093
-
-
Murase, K.1
-
112
-
-
84874274026
-
How membrane structures control T cell signaling
-
Klammt C, Lillemeier BF. How membrane structures control T cell signaling. Front Immunol 2012;3:291.
-
(2012)
Front Immunol
, vol.3
, pp. 291
-
-
Klammt, C.1
Lillemeier, B.F.2
-
113
-
-
76949108167
-
The membrane skeleton controls diffusion dynamics and signaling through the B cell receptor
-
Treanor B, et al. The membrane skeleton controls diffusion dynamics and signaling through the B cell receptor. Immunity 2010;32:187-199.
-
(2010)
Immunity
, vol.32
, pp. 187-199
-
-
Treanor, B.1
-
114
-
-
84875538701
-
The actin and tetraspanin networks organize receptor nanoclusters to regulate B cell receptor-mediated signaling
-
Mattila PK, et al. The actin and tetraspanin networks organize receptor nanoclusters to regulate B cell receptor-mediated signaling. Immunity 2013;38:461-474.
-
(2013)
Immunity
, vol.38
, pp. 461-474
-
-
Mattila, P.K.1
-
115
-
-
0029037210
-
Serial triggering of many T-cell receptors by a few peptide-MHC complexes
-
Valitutti S, Muller S, Cella M, Padovan E, Lanzavecchia A. Serial triggering of many T-cell receptors by a few peptide-MHC complexes. Nature 1995;375:148-151.
-
(1995)
Nature
, vol.375
, pp. 148-151
-
-
Valitutti, S.1
Muller, S.2
Cella, M.3
Padovan, E.4
Lanzavecchia, A.5
-
116
-
-
77951688913
-
Isolation of cytotoxic T cell and NK granules and purification of thir effector proteins
-
37.29.
-
Thiery J, Walch M, Jensen DK, Martinvalet D, Lieberman J. Isolation of cytotoxic T cell and NK granules and purification of thir effector proteins. Curr Protocols Cell Biol 2010;47:1-3.37.29.
-
(2010)
Curr Protocols Cell Biol
, vol.47
, pp. 1-3
-
-
Thiery, J.1
Walch, M.2
Jensen, D.K.3
Martinvalet, D.4
Lieberman, J.5
-
117
-
-
0027457958
-
Lytic granules from cytotoxic T cells exhibit kinesin-dependent motility on microtubules in vitro
-
Burkhardt JK, McIlvain JM Jr, Sheetz MP, Argon Y. Lytic granules from cytotoxic T cells exhibit kinesin-dependent motility on microtubules in vitro. J Cell Sci 1993;205:151-162.
-
(1993)
J Cell Sci
, vol.205
, pp. 151-162
-
-
Burkhardt, J.K.1
McIlvain Jr., J.M.2
Sheetz, M.P.3
Argon, Y.4
-
118
-
-
33749185296
-
Centrosome polarization delivers secretory granules to the immunological synapse
-
Stinchcombe JC, Majorovits E, Bossi G, Fuller S, Griffiths GM. Centrosome polarization delivers secretory granules to the immunological synapse. Nature 2006;443:462-465.
-
(2006)
Nature
, vol.443
, pp. 462-465
-
-
Stinchcombe, J.C.1
Majorovits, E.2
Bossi, G.3
Fuller, S.4
Griffiths, G.M.5
-
119
-
-
0021714772
-
Reorientation of the microtubule-organizing center and the Golgi apparatus in cloned cytotoxic lymphocytes triggered by binding to lysable target cells
-
Kupfer A, Dennert G. Reorientation of the microtubule-organizing center and the Golgi apparatus in cloned cytotoxic lymphocytes triggered by binding to lysable target cells. J Immunol 1984;133:2762-2766.
-
(1984)
J Immunol
, vol.133
, pp. 2762-2766
-
-
Kupfer, A.1
Dennert, G.2
-
120
-
-
0020455120
-
Mechanisms of human cell-mediated cytotoxicity. III. Dependence of natural killing on microtubule and microfilament integrity
-
Katz P, Zaytoun AM, Lee JH Jr. Mechanisms of human cell-mediated cytotoxicity. III. Dependence of natural killing on microtubule and microfilament integrity. J Immunol 1982;129:2816-2825.
-
(1982)
J Immunol
, vol.129
, pp. 2816-2825
-
-
Katz, P.1
Zaytoun, A.M.2
Lee Jr., J.H.3
-
121
-
-
0345060886
-
The mature activating natural killer cell immunologic synapse is formed in distinct stages
-
Orange JS, Harris KE, Andzelm MM, Valter MM, Geha RS, Strominger JL. The mature activating natural killer cell immunologic synapse is formed in distinct stages. Proc Natl Acad Sci USA 2003;100:14151-14156.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 14151-14156
-
-
Orange, J.S.1
Harris, K.E.2
Andzelm, M.M.3
Valter, M.M.4
Geha, R.S.5
Strominger, J.L.6
-
122
-
-
27344449286
-
Human decidual NK cells form immature activating synapses and are not cytotoxic
-
Kopcow HD, et al. Human decidual NK cells form immature activating synapses and are not cytotoxic. Proc Natl Acad Sci USA 2005;102:15563-15568.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 15563-15568
-
-
Kopcow, H.D.1
-
123
-
-
33745882375
-
CD28-stimulated ERK2 phosphorylation is required for polarization of the microtubule organizing center and granules in YTS NK cells
-
Chen X, Allan DSJ, Krzewski K, Ge BX, Kopcow H, Strominger JL. CD28-stimulated ERK2 phosphorylation is required for polarization of the microtubule organizing center and granules in YTS NK cells. Proc Natl Acad Sci USA 2006;103:10346-10351.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 10346-10351
-
-
Chen, X.1
Allan, D.S.J.2
Krzewski, K.3
Ge, B.X.4
Kopcow, H.5
Strominger, J.L.6
-
124
-
-
34948842343
-
Cdc42-interacting protein-4 functionally links actin and microtubule networks at the cytolytic NK cell immunological synapse
-
Banerjee PP, Pandey R, Zheng R, Suhoski MM, Monaco-Shawver L, Orange JS. Cdc42-interacting protein-4 functionally links actin and microtubule networks at the cytolytic NK cell immunological synapse. J Exp Med 2007;204:2305-2320.
-
(2007)
J Exp Med
, vol.204
, pp. 2305-2320
-
-
Banerjee, P.P.1
Pandey, R.2
Zheng, R.3
Suhoski, M.M.4
Monaco-Shawver, L.5
Orange, J.S.6
-
125
-
-
77954197189
-
Rapid lytic granule convergence to the MTOC in natural killer cells is dependent on dynein but not cytolytic commitment
-
Mentlik AN, Sanborn KB, Holzbaur EL, Orange JS. Rapid lytic granule convergence to the MTOC in natural killer cells is dependent on dynein but not cytolytic commitment. Mol Biol Cell 2010;21:2241-2256.
-
(2010)
Mol Biol Cell
, vol.21
, pp. 2241-2256
-
-
Mentlik, A.N.1
Sanborn, K.B.2
Holzbaur, E.L.3
Orange, J.S.4
-
126
-
-
0033789351
-
Dynactin increases the processivity of the cytoplasmic dynein motor
-
King SJ, Schroer TA. Dynactin increases the processivity of the cytoplasmic dynein motor. Nat Cell Biol 2000;2:20-24.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 20-24
-
-
King, S.J.1
Schroer, T.A.2
-
127
-
-
67349243386
-
Localized diacylglycerol drives the polarization of the microtubule-organizing center in T cells
-
Quann EJ, Merino E, Furuta T, Huse M. Localized diacylglycerol drives the polarization of the microtubule-organizing center in T cells. Nat Immunol 2009;10:627-696.
-
(2009)
Nat Immunol
, vol.10
, pp. 627-696
-
-
Quann, E.J.1
Merino, E.2
Furuta, T.3
Huse, M.4
-
128
-
-
79958765719
-
A role for Rab7 in the movement of secretory granules in cytotoxic T lymphocytes
-
Daniele T, et al. A role for Rab7 in the movement of secretory granules in cytotoxic T lymphocytes. Traffic 2011;12:902-911.
-
(2011)
Traffic
, vol.12
, pp. 902-911
-
-
Daniele, T.1
-
129
-
-
34249668425
-
Organelle proteomics: identification of the exocytic machinery associated with the natural killer cell secretory lysosome
-
Casey TM, Meade JL, Hewitt EW. Organelle proteomics: identification of the exocytic machinery associated with the natural killer cell secretory lysosome. Mol Cell Proteomics 2007;6:767-780.
-
(2007)
Mol Cell Proteomics
, vol.6
, pp. 767-780
-
-
Casey, T.M.1
Meade, J.L.2
Hewitt, E.W.3
-
130
-
-
84881065930
-
LAMP1/CD107a is required for efficient perforin delivery to lytic granules and NK cell cytotoxicity
-
Krzewski K, Gil-Krzewska A, Nguyen V, Peruzzi G, Coligan JE. LAMP1/CD107a is required for efficient perforin delivery to lytic granules and NK cell cytotoxicity. Blood 2013;121:4672-4683.
-
(2013)
Blood
, vol.121
, pp. 4672-4683
-
-
Krzewski, K.1
Gil-Krzewska, A.2
Nguyen, V.3
Peruzzi, G.4
Coligan, J.E.5
-
131
-
-
84876061817
-
An initial and rapid step of lytic granule secretion precedes microtubule organizing center polarization at the cytotoxic T lymphocyte/target cell synapse
-
Bertrand F, Muller S, Roh KH, Laurent C, Dupre L, Valitutti S. An initial and rapid step of lytic granule secretion precedes microtubule organizing center polarization at the cytotoxic T lymphocyte/target cell synapse. Proc Natl Acad Sci USA 2013;110:6073-6078.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 6073-6078
-
-
Bertrand, F.1
Muller, S.2
Roh, K.H.3
Laurent, C.4
Dupre, L.5
Valitutti, S.6
-
132
-
-
0029008280
-
Regulation of the Polarization of T-Cells toward Antigen-Presenting Cells by Ras-Related Gtpase Cdc42
-
Stowers L, Yelon D, Berg LJ, Chant J. Regulation of the Polarization of T-Cells toward Antigen-Presenting Cells by Ras-Related Gtpase Cdc42. Proc Natl Acad Sci USA 1995;92:5027-5031.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 5027-5031
-
-
Stowers, L.1
Yelon, D.2
Berg, L.J.3
Chant, J.4
-
133
-
-
33746215226
-
Specific patterns of Cdc42 activity are related to distinct elements of T cell polarization
-
Tskvitaria-Fuller I, Seth A, Mistry N, Gu H, Rosen MK, Wulfing C. Specific patterns of Cdc42 activity are related to distinct elements of T cell polarization. J Immunol 2006;177:1708-1720.
-
(2006)
J Immunol
, vol.177
, pp. 1708-1720
-
-
Tskvitaria-Fuller, I.1
Seth, A.2
Mistry, N.3
Gu, H.4
Rosen, M.K.5
Wulfing, C.6
-
134
-
-
18444369936
-
Rac1 and Cdc42 capture microtubules through IQGAP1 and CLIP-170
-
Fukata M, et al. Rac1 and Cdc42 capture microtubules through IQGAP1 and CLIP-170. Cell 2002;109:873-885.
-
(2002)
Cell
, vol.109
, pp. 873-885
-
-
Fukata, M.1
-
135
-
-
84860330652
-
Terminal transport of lytic granules to the immune synapse is mediated by the kinesin-1/Slp3/Rab27a complex
-
Kurowska M, et al. Terminal transport of lytic granules to the immune synapse is mediated by the kinesin-1/Slp3/Rab27a complex. Blood 2012;119:3879-3889.
-
(2012)
Blood
, vol.119
, pp. 3879-3889
-
-
Kurowska, M.1
-
136
-
-
77958466893
-
Distinct role of Rab27a in granule movement at the plasma membrane and in the cytosol of NK cells
-
Liu D, Meckel T, Long EO. Distinct role of Rab27a in granule movement at the plasma membrane and in the cytosol of NK cells. PLoS ONE 2010;5:e12870.
-
(2010)
PLoS ONE
, vol.5
-
-
Liu, D.1
Meckel, T.2
Long, E.O.3
-
137
-
-
34247880547
-
Secretory cytotoxic granule maturation and exocytosis require the effector protein hMunc13-4
-
Menager MM, et al. Secretory cytotoxic granule maturation and exocytosis require the effector protein hMunc13-4. Nat Immunol 2007;8:257-267.
-
(2007)
Nat Immunol
, vol.8
, pp. 257-267
-
-
Menager, M.M.1
-
138
-
-
34948877989
-
Myosin IIA is required for cytolytic granule exocytosis in human NK cells
-
Andzelm MM, Chen X, Krzewski K, Orange JS, Strominger JL. Myosin IIA is required for cytolytic granule exocytosis in human NK cells. J Exp Med 2007;204:2285-2291.
-
(2007)
J Exp Med
, vol.204
, pp. 2285-2291
-
-
Andzelm, M.M.1
Chen, X.2
Krzewski, K.3
Orange, J.S.4
Strominger, J.L.5
-
139
-
-
67449141628
-
Myosin IIA associates with NK cell lytic granules to enable their interaction with F-actin and function at the immunological synapse
-
Sanborn KB, et al. Myosin IIA associates with NK cell lytic granules to enable their interaction with F-actin and function at the immunological synapse. J Immunol 2009;182:6969-6984.
-
(2009)
J Immunol
, vol.182
, pp. 6969-6984
-
-
Sanborn, K.B.1
-
140
-
-
0037443541
-
The size of the synaptic cleft and distinct distributions of filamentous actin, ezrin, CD43, and CD45 at activating and inhibitory human NK cell immune synapses
-
McCann FE, et al. The size of the synaptic cleft and distinct distributions of filamentous actin, ezrin, CD43, and CD45 at activating and inhibitory human NK cell immune synapses. J Immunol 2003;170:2862-2870.
-
(2003)
J Immunol
, vol.170
, pp. 2862-2870
-
-
McCann, F.E.1
-
141
-
-
80053321288
-
Natural killer cell lytic granule secretion occurs through a pervasive actin network at the immune synapse
-
Rak GD, Mace EM, Banerjee PP, Svitkina T, Orange JS. Natural killer cell lytic granule secretion occurs through a pervasive actin network at the immune synapse. PLoS Biol 2011;9:e1001151.
-
(2011)
PLoS Biol
, vol.9
-
-
Rak, G.D.1
Mace, E.M.2
Banerjee, P.P.3
Svitkina, T.4
Orange, J.S.5
-
142
-
-
84868528135
-
Dual channel STED nanoscopy of lytic granules on actin filaments in natural killer cells
-
Mace EM, Orange JS. Dual channel STED nanoscopy of lytic granules on actin filaments in natural killer cells. Commun Integr Biol 2012;5:184-186.
-
(2012)
Commun Integr Biol
, vol.5
, pp. 184-186
-
-
Mace, E.M.1
Orange, J.S.2
-
143
-
-
0025978984
-
Polarized expression of cytokines in cell conjugates of helper T-cells and splenic B-cells
-
Kupfer A, Mosmann TR, Kupfer H. Polarized expression of cytokines in cell conjugates of helper T-cells and splenic B-cells. Proc Natl Acad Sci USA 1991;88:775-779.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 775-779
-
-
Kupfer, A.1
Mosmann, T.R.2
Kupfer, H.3
-
144
-
-
40749085632
-
In vivo polarization of IFN-gamma at Kupfer and non-Kupfer immunological synapses during the clearance of virally infected brain cells
-
Barcia C, Wawrowsky K, Barrett RJ, Liu C, Castro MG, Lowenstein PR. In vivo polarization of IFN-gamma at Kupfer and non-Kupfer immunological synapses during the clearance of virally infected brain cells. J Immunol 2008;180:1344-1352.
-
(2008)
J Immunol
, vol.180
, pp. 1344-1352
-
-
Barcia, C.1
Wawrowsky, K.2
Barrett, R.J.3
Liu, C.4
Castro, M.G.5
Lowenstein, P.R.6
-
145
-
-
0035313266
-
Cutting edge: in vivo identification of TCR redistribution and polarized IL-2 production by naive CD4 T cells
-
Reichert P, Reinhardt RL, Ingulli E, Jenkins MK. Cutting edge: in vivo identification of TCR redistribution and polarized IL-2 production by naive CD4 T cells. J Immunol 2001;166:4278-4281.
-
(2001)
J Immunol
, vol.166
, pp. 4278-4281
-
-
Reichert, P.1
Reinhardt, R.L.2
Ingulli, E.3
Jenkins, M.K.4
-
146
-
-
84868549451
-
Super-resolution imaging of remodeled synaptic actin reveals different synergies between NK cell receptors and integrins
-
Brown ACN, Dobbie IM, Alakoskela JM, Davis I, Davis DM. Super-resolution imaging of remodeled synaptic actin reveals different synergies between NK cell receptors and integrins. Blood 2012;120:3729-3740.
-
(2012)
Blood
, vol.120
, pp. 3729-3740
-
-
Brown, A.C.N.1
Dobbie, I.M.2
Alakoskela, J.M.3
Davis, I.4
Davis, D.M.5
-
147
-
-
83255176862
-
The new faces of endocytosis in signaling
-
Hupalowska A, Miaczynska M. The new faces of endocytosis in signaling. Traffic 2011;13:1-10.
-
(2011)
Traffic
, vol.13
, pp. 1-10
-
-
Hupalowska, A.1
Miaczynska, M.2
-
148
-
-
67349103762
-
Signaling from endosomes: location makes a difference
-
Sadowski L, Pilecka I, Miaczynska M. Signaling from endosomes: location makes a difference. Exp Cell Res 2009;315:1601-1609.
-
(2009)
Exp Cell Res
, vol.315
, pp. 1601-1609
-
-
Sadowski, L.1
Pilecka, I.2
Miaczynska, M.3
-
149
-
-
62649159446
-
Endocytosis and intracellular trafficking of ErbBs
-
Sorkin A, Goh LK. Endocytosis and intracellular trafficking of ErbBs. Exp Cell Res 2009;315:683-696.
-
(2009)
Exp Cell Res
, vol.315
, pp. 683-696
-
-
Sorkin, A.1
Goh, L.K.2
-
150
-
-
70449552889
-
Endosomes: a legitimate platform for the signaling train
-
Murphy JE, Padilla BE, Hasdemir B, Cottrell GS, Bunnett NW. Endosomes: a legitimate platform for the signaling train. Proc Natl Acad Sci USA 2009;106:17615-17622.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 17615-17622
-
-
Murphy, J.E.1
Padilla, B.E.2
Hasdemir, B.3
Cottrell, G.S.4
Bunnett, N.W.5
-
151
-
-
84875604499
-
Conformational biosensors reveal GPCR signalling from endosomes
-
Irannejad R, et al. Conformational biosensors reveal GPCR signalling from endosomes. Nature 2013;495:534-538.
-
(2013)
Nature
, vol.495
, pp. 534-538
-
-
Irannejad, R.1
-
152
-
-
77953827161
-
Dynamics of subsynaptic vesicles and surface microclusters at the immunological synapse
-
Purbhoo MA, et al. Dynamics of subsynaptic vesicles and surface microclusters at the immunological synapse. Sci Signal 2010;3:ra36.
-
(2010)
Sci Signal
, vol.3
-
-
Purbhoo, M.A.1
-
153
-
-
79959373064
-
Pre-existing clusters of the adaptor Lat do not participate in early T cell signaling events
-
Williamson DJ, et al. Pre-existing clusters of the adaptor Lat do not participate in early T cell signaling events. Nat Immunol 2011;12:655-662.
-
(2011)
Nat Immunol
, vol.12
, pp. 655-662
-
-
Williamson, D.J.1
-
154
-
-
31144460282
-
Activation of NK cells by an endocytosed receptor for soluble HLA-G
-
Rajagopalan S, et al. Activation of NK cells by an endocytosed receptor for soluble HLA-G. PLoS Biol 2006;4:e9.
-
(2006)
PLoS Biol
, vol.4
-
-
Rajagopalan, S.1
-
155
-
-
0036719573
-
Natural killer cells and pregnancy
-
Moffett-King A. Natural killer cells and pregnancy. Nat Rev Immunol 2002;2:656-663.
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 656-663
-
-
Moffett-King, A.1
-
156
-
-
0023658307
-
Heterogeneous mutations in the beta-subunit common to the LFA-1, MAC-1, and P150,95 glycoproteins cause leukocyte adhesion deficiency
-
Kishimoto TK, Hollander N, Roberts TM, Anderson DC, Springer TA. Heterogeneous mutations in the beta-subunit common to the LFA-1, MAC-1, and P150, 95 glycoproteins cause leukocyte adhesion deficiency. Cell 1987;50:193-202.
-
(1987)
Cell
, vol.50
, pp. 193-202
-
-
Kishimoto, T.K.1
Hollander, N.2
Roberts, T.M.3
Anderson, D.C.4
Springer, T.A.5
-
157
-
-
4644324573
-
LFA-1 contributes an early signal for NK cell cytotoxicity
-
Barber DF, Faure M, Long EO. LFA-1 contributes an early signal for NK cell cytotoxicity. J Immunol 2004;173:3653-3659.
-
(2004)
J Immunol
, vol.173
, pp. 3653-3659
-
-
Barber, D.F.1
Faure, M.2
Long, E.O.3
-
158
-
-
0022237923
-
Heritable lymphocyte function-associated antigen-1 deficiency - abnormalitites of cyto-toxicity and proliferation associated with abnormal expression of LFA-1
-
Krensky AM, et al. Heritable lymphocyte function-associated antigen-1 deficiency - abnormalitites of cyto-toxicity and proliferation associated with abnormal expression of LFA-1. J Immunol 1985;135:3102-3108.
-
(1985)
J Immunol
, vol.135
, pp. 3102-3108
-
-
Krensky, A.M.1
-
159
-
-
1642581670
-
LAD-III, a leukocyte adhesion deficiency syndrome associated with defective Rap1 activation and impaired stabilization of integrin bonds
-
Kinashi T, et al. LAD-III, a leukocyte adhesion deficiency syndrome associated with defective Rap1 activation and impaired stabilization of integrin bonds. Blood 2004;103:1033-1036.
-
(2004)
Blood
, vol.103
, pp. 1033-1036
-
-
Kinashi, T.1
-
160
-
-
55249083592
-
Kindlin-3: a new gene involved in the pathogenesis of LAD-III
-
Mory A, et al. Kindlin-3: a new gene involved in the pathogenesis of LAD-III. Blood 2008;112:2591.
-
(2008)
Blood
, vol.112
, pp. 2591
-
-
Mory, A.1
-
162
-
-
3142585003
-
Impaired natural and CD16-mediated NK cell cytotoxicity in patients with WAS and XLT: ability of IL-2 to correct NK cell functional defect
-
Gismondi A, et al. Impaired natural and CD16-mediated NK cell cytotoxicity in patients with WAS and XLT: ability of IL-2 to correct NK cell functional defect. Blood 2004;104:436-443.
-
(2004)
Blood
, vol.104
, pp. 436-443
-
-
Gismondi, A.1
-
163
-
-
14044276352
-
The Wiskott-Aldrich syndrome protein regulates nuclear translocation of NFAT2 and NF-kappa B (RelA) independently of its role in filamentous actin polymerization and actin cytoskeletal rearrangement
-
Huang W, Ochs HD, Dupont B, Vyas YM. The Wiskott-Aldrich syndrome protein regulates nuclear translocation of NFAT2 and NF-kappa B (RelA) independently of its role in filamentous actin polymerization and actin cytoskeletal rearrangement. J Immunol 2005;174:2602-2611.
-
(2005)
J Immunol
, vol.174
, pp. 2602-2611
-
-
Huang, W.1
Ochs, H.D.2
Dupont, B.3
Vyas, Y.M.4
-
164
-
-
79953331939
-
IL-2 induces a WAVE2-dependent pathway for actin reorganization that enables WASp-independent human NK cell function
-
Orange JS, et al. IL-2 induces a WAVE2-dependent pathway for actin reorganization that enables WASp-independent human NK cell function. J Clin Invest 2011;121:1535-1548.
-
(2011)
J Clin Invest
, vol.121
, pp. 1535-1548
-
-
Orange, J.S.1
-
165
-
-
84875226021
-
Defective actin accumulation impairs human natural killer cell function in patients with dedicator of cytokinesis 8 deficiency
-
Mizesko MC, et al. Defective actin accumulation impairs human natural killer cell function in patients with dedicator of cytokinesis 8 deficiency. J Allergy Clin Immunol 2013;131:840-848.
-
(2013)
J Allergy Clin Immunol
, vol.131
, pp. 840-848
-
-
Mizesko, M.C.1
-
166
-
-
70949098060
-
Combined immunodeficiency associated with DOCK8 mutations
-
Zhang Q, et al. Combined immunodeficiency associated with DOCK8 mutations. N Engl J Med 2009;361:2046-2055.
-
(2009)
N Engl J Med
, vol.361
, pp. 2046-2055
-
-
Zhang, Q.1
-
167
-
-
84868014580
-
Vav1 haploinsufficiency in a common variable immunodeficiency patient with defective T-cell function
-
Capitani N, et al. Vav1 haploinsufficiency in a common variable immunodeficiency patient with defective T-cell function. Int J Immunopathol Pharmacol 2012;25:811-817.
-
(2012)
Int J Immunopathol Pharmacol
, vol.25
, pp. 811-817
-
-
Capitani, N.1
-
168
-
-
22144473737
-
Defective Vav expression and impaired F-actin reorganization in a subset of patients with common variable immunodeficiency characterized by T-cell defects
-
Paccani SR, et al. Defective Vav expression and impaired F-actin reorganization in a subset of patients with common variable immunodeficiency characterized by T-cell defects. Blood 2005;106:626-634.
-
(2005)
Blood
, vol.106
, pp. 626-634
-
-
Paccani, S.R.1
-
169
-
-
4644359297
-
Differential requirements for Vav proteins in DAP10- and ITAM-mediated NK cell cytotoxicity
-
Cella M, et al. Differential requirements for Vav proteins in DAP10- and ITAM-mediated NK cell cytotoxicity. J Exp Med 2004;200:817-823.
-
(2004)
J Exp Med
, vol.200
, pp. 817-823
-
-
Cella, M.1
-
170
-
-
33746901647
-
Vav1 controls DAP10-mediated natural cytotoxicity by regulating actin and microtubule dynamics
-
Graham DB, et al. Vav1 controls DAP10-mediated natural cytotoxicity by regulating actin and microtubule dynamics. J Immunol 2006;177:2349-2355.
-
(2006)
J Immunol
, vol.177
, pp. 2349-2355
-
-
Graham, D.B.1
-
171
-
-
33645976783
-
NKG2D-mediated signaling requires a DAP10-bound Grb2-Vav1 intermediate and phosphatidylinositol-3-kinase in human natural killer cells
-
Upshaw JL, Arneson LN, Schoon RA, Dick CJ, Billadeau DD, Leibson PJ. NKG2D-mediated signaling requires a DAP10-bound Grb2-Vav1 intermediate and phosphatidylinositol-3-kinase in human natural killer cells. Nat Immunol 2006;7:524-532.
-
(2006)
Nat Immunol
, vol.7
, pp. 524-532
-
-
Upshaw, J.L.1
Arneson, L.N.2
Schoon, R.A.3
Dick, C.J.4
Billadeau, D.D.5
Leibson, P.J.6
-
172
-
-
0043125648
-
Vav1 phosphorylation is induced by beta2 integrin engagement on natural killer cells upstream of actin cytoskeleton and lipid raft reorganization
-
Riteau B, Barber DF, Long EO. Vav1 phosphorylation is induced by beta2 integrin engagement on natural killer cells upstream of actin cytoskeleton and lipid raft reorganization. J Exp Med 2003;198:469-474.
-
(2003)
J Exp Med
, vol.198
, pp. 469-474
-
-
Riteau, B.1
Barber, D.F.2
Long, E.O.3
-
173
-
-
0344002689
-
Mutations in RAB27A cause Griscelli syndrome associated with haemophagocytic syndrome
-
Menasche G, et al. Mutations in RAB27A cause Griscelli syndrome associated with haemophagocytic syndrome. Nat Genet 2000;25:173-176.
-
(2000)
Nat Genet
, vol.25
, pp. 173-176
-
-
Menasche, G.1
-
174
-
-
0035911160
-
Rab27a is required for regulated secretion in cytotoxic T lymphocytes
-
Stinchcombe JC, et al. Rab27a is required for regulated secretion in cytotoxic T lymphocytes. J Cell Biol 2001;152:825-834.
-
(2001)
J Cell Biol
, vol.152
, pp. 825-834
-
-
Stinchcombe, J.C.1
-
175
-
-
72949100151
-
Different NK cell-activating receptors preferentially recruit Rab27a or Munc13-4 to perforin-containing granules for cytotoxicity
-
Wood SM, et al. Different NK cell-activating receptors preferentially recruit Rab27a or Munc13-4 to perforin-containing granules for cytotoxicity. Blood 2009;114:4117-4127.
-
(2009)
Blood
, vol.114
, pp. 4117-4127
-
-
Wood, S.M.1
-
176
-
-
10744224641
-
Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3)
-
Feldmann J, et al. Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3). Cell 2003;115:461-473.
-
(2003)
Cell
, vol.115
, pp. 461-473
-
-
Feldmann, J.1
-
177
-
-
80051639052
-
The munc13-4-rab27 complex is specifically required for tethering secretory lysosomes at the plasma membrane
-
Elstak ED, et al. The munc13-4-rab27 complex is specifically required for tethering secretory lysosomes at the plasma membrane. Blood 2011;118:1570-1578.
-
(2011)
Blood
, vol.118
, pp. 1570-1578
-
-
Elstak, E.D.1
-
178
-
-
34248370215
-
NK cytotoxicity mediated by CD16 but not by NKp30 is functional in Griscelli syndrome
-
Gazit R, et al. NK cytotoxicity mediated by CD16 but not by NKp30 is functional in Griscelli syndrome. Blood 2007;109:4306-4312.
-
(2007)
Blood
, vol.109
, pp. 4306-4312
-
-
Gazit, R.1
-
179
-
-
0033007616
-
Altered trafficking of lysosomal proteins in Hermansky-Pudlak syndrome due to mutations in the beta 3A subunit of the AP-3 adaptor
-
Dell'Angelica EC, Shotelersuk V, Aguilar RC, Gahl WA, Bonifacino JS. Altered trafficking of lysosomal proteins in Hermansky-Pudlak syndrome due to mutations in the beta 3A subunit of the AP-3 adaptor. Mol Cell 1999;3:11-21.
-
(1999)
Mol Cell
, vol.3
, pp. 11-21
-
-
Dell'Angelica, E.C.1
Shotelersuk, V.2
Aguilar, R.C.3
Gahl, W.A.4
Bonifacino, J.S.5
-
180
-
-
0242539818
-
Adaptor protein 3-dependent microtubule-mediated movement of lytic granules to the immunological synapse
-
Clark RH, et al. Adaptor protein 3-dependent microtubule-mediated movement of lytic granules to the immunological synapse. Nat Immunol 2003;4:1111-1120.
-
(2003)
Nat Immunol
, vol.4
, pp. 1111-1120
-
-
Clark, R.H.1
-
181
-
-
33745083115
-
Innate immunity defects in Hermansky-Pudlak type 2 syndrome
-
Fontana S, et al. Innate immunity defects in Hermansky-Pudlak type 2 syndrome. Blood 2006;107:4857-4864.
-
(2006)
Blood
, vol.107
, pp. 4857-4864
-
-
Fontana, S.1
-
182
-
-
0027937223
-
Isolation of a novel gene mutated in Wiskott-Aldrich syndrome
-
Derry JMJ, Ochs HD, Francke U. Isolation of a novel gene mutated in Wiskott-Aldrich syndrome. Cell 1994;78:635-644.
-
(1994)
Cell
, vol.78
, pp. 635-644
-
-
Derry, J.M.J.1
Ochs, H.D.2
Francke, U.3
-
183
-
-
0034911925
-
Regulation of actin filament network formation through Arp2/3 complex: activation by a diverse array of proteins
-
Higgs HN, Pollard TD. Regulation of actin filament network formation through Arp2/3 complex: activation by a diverse array of proteins. Annu Rev Biochem 2001;70:649-676.
-
(2001)
Annu Rev Biochem
, vol.70
, pp. 649-676
-
-
Higgs, H.N.1
Pollard, T.D.2
-
184
-
-
0034506070
-
The Wiskott-Aldrich syndrome: disordered actin dynamics in haematopoietic cells
-
Thrasher AJ, Burns S, Lorenzi R, Jones GE. The Wiskott-Aldrich syndrome: disordered actin dynamics in haematopoietic cells. Immunol Rev 2000;178:118-128.
-
(2000)
Immunol Rev
, vol.178
, pp. 118-128
-
-
Thrasher, A.J.1
Burns, S.2
Lorenzi, R.3
Jones, G.E.4
-
185
-
-
0034783368
-
Characterization of four CD18 mutants in leucocyte adhesion deficient (LAD) patients with differential capacities to support expression and function of the CD11/CD18 integrins LFA-1, Mac-1 and p150,95
-
Shaw JM, et al. Characterization of four CD18 mutants in leucocyte adhesion deficient (LAD) patients with differential capacities to support expression and function of the CD11/CD18 integrins LFA-1, Mac-1 and p150, 95. Clin Exp Immunol 2001;126:311-318.
-
(2001)
Clin Exp Immunol
, vol.126
, pp. 311-318
-
-
Shaw, J.M.1
-
186
-
-
0033626342
-
Interleukin-2 mediated restoration of natural killer cell function in a patient with Griscelli syndrome
-
Plebani A, Ciravegna B, Ponte M, Mingari MC, Moretta L. Interleukin-2 mediated restoration of natural killer cell function in a patient with Griscelli syndrome. Eur J Pediatr 2000;159:713-714.
-
(2000)
Eur J Pediatr
, vol.159
, pp. 713-714
-
-
Plebani, A.1
Ciravegna, B.2
Ponte, M.3
Mingari, M.C.4
Moretta, L.5
-
188
-
-
0019985228
-
Deficiency of active natural killer cells in the Chediak-Higashi syndrome. Localization of the defect using a single cell cytotoxicity assay
-
Katz P, Zaytoun AM, Fauci AS. Deficiency of active natural killer cells in the Chediak-Higashi syndrome. Localization of the defect using a single cell cytotoxicity assay. J Clin Invest 1982;69:1231-1238.
-
(1982)
J Clin Invest
, vol.69
, pp. 1231-1238
-
-
Katz, P.1
Zaytoun, A.M.2
Fauci, A.S.3
-
189
-
-
0029039291
-
Loss of cytotoxic T lymphocyte function in Chediak-Higashi syndrome arises from a secretory defect that prevents lytic granule exocytosis
-
Baetz K, Isaaz S, Griffiths GM. Loss of cytotoxic T lymphocyte function in Chediak-Higashi syndrome arises from a secretory defect that prevents lytic granule exocytosis. J Immunol 1995;154:6122-6131.
-
(1995)
J Immunol
, vol.154
, pp. 6122-6131
-
-
Baetz, K.1
Isaaz, S.2
Griffiths, G.M.3
-
190
-
-
0020624576
-
The "lazy" NK cells of Chediak-Higashi syndrome
-
Targan SR, Oseas R. The "lazy" NK cells of Chediak-Higashi syndrome. J Immunol 1983;130:2671-2674.
-
(1983)
J Immunol
, vol.130
, pp. 2671-2674
-
-
Targan, S.R.1
Oseas, R.2
-
191
-
-
80055087431
-
Subtle differences in CTL cytotoxicity determine susceptibility to hemophagocytic lymphohistiocytosis in mice and humans with Chediak-Higashi syndrome
-
Jessen B, et al. Subtle differences in CTL cytotoxicity determine susceptibility to hemophagocytic lymphohistiocytosis in mice and humans with Chediak-Higashi syndrome. Blood 2011;118:4620-4629.
-
(2011)
Blood
, vol.118
, pp. 4620-4629
-
-
Jessen, B.1
-
192
-
-
33745633063
-
Lethal hemophagocytic lymphohistiocytosis in Hermansky-Pudlak syndrome type II
-
Enders A, et al. Lethal hemophagocytic lymphohistiocytosis in Hermansky-Pudlak syndrome type II. Blood 2006;108:81-87.
-
(2006)
Blood
, vol.108
, pp. 81-87
-
-
Enders, A.1
-
193
-
-
34948856458
-
Novel insights from adaptor protein 3 complex deficiency
-
quiz 742-743.
-
Badolato R, Parolini S. Novel insights from adaptor protein 3 complex deficiency. J Allergy Clin Immunol 2007;120:735-741; quiz 742-743.
-
(2007)
J Allergy Clin Immunol
, vol.120
, pp. 735-741
-
-
Badolato, R.1
Parolini, S.2
|