-
1
-
-
0033534533
-
Adaptors and molecular scaffolds in immune cell signaling
-
C. E. Rudd, Adaptors and molecular scaffolds in immune cell signaling. Cell 96, 5-8 (1999).
-
(1999)
Cell.
, vol.96
, pp. 5-8
-
-
Rudd, C.E.1
-
2
-
-
0030906543
-
Regulation of Vav-SLP-76 binding by ZAP-70 and its relevance to TCRz/CD3 induction of interleukin-2
-
M. Raab, A. J. da Silva, P. R. Findell, C. E. Rudd, Regulation of Vav-SLP-76 binding by ZAP-70 and its relevance to TCRz/CD3 induction of interleukin-2. Immunity 6, 155-164 (1997).
-
(1997)
Immunity
, vol.6
, pp. 155-164
-
-
Raab, M.1
Da Silva, A.J.2
Findell, P.R.3
Rudd, C.E.4
-
3
-
-
0032498231
-
LAT: The ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation
-
W. Zhang, J. Sloan-Lancaster, J. Kitchen, R. P. Trible, L. E. Samelson, LAT: The ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation. Cell 92, 83-92 (1998).
-
(1998)
Cell.
, vol.92
, pp. 83-92
-
-
Zhang, W.1
Sloan-Lancaster, J.2
Kitchen, J.3
Trible, R.P.4
Samelson, L.E.5
-
4
-
-
0000082758
-
Phosphorylation of SLP-76 by the ZAP-70 protein-tyrosine kinase is required for T-cell receptor function
-
J. Bubeck Wardenburg, C. Fu, J. K. Jackman, H. Flotow, S. E. Wilkinson, D. H. Williams, R. Johnson, G. Kong, A. C. Chan, P. R. Findell, Phosphorylation of SLP-76 by the ZAP-70 protein-tyrosine kinase is required for T-cell receptor function. J. Biol. Chem. 271, 19641-19644 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 19641-19644
-
-
Wardenburg, J.B.1
Fu, C.2
Jackman, J.K.3
Flotow, H.4
Wilkinson, S.E.5
Williams, D.H.6
Johnson, R.7
Kong, G.8
Chan, A.C.9
Findell, P.R.10
-
5
-
-
0033519283
-
Grf40, a novel Grb2 familymember, is involved in T cell signaling through interaction with SLP-76 and LAT
-
H. Asada, N. Ishii, Y. Sasaki, K. Endo, H. Kasai, N. Tanaka, T. Takeshita, S. Tsuchiya, T. Konno, K. Sugamura, Grf40, a novel Grb2 familymember, is involved in T cell signaling through interaction with SLP-76 and LAT. J. Exp. Med. 189, 1383-1390 (1999).
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1383-1390
-
-
Asada, H.1
Ishii, N.2
Sasaki, Y.3
Endo, K.4
Kasai, H.5
Tanaka, N.6
Takeshita, T.7
Tsuchiya, S.8
Konno, T.9
Sugamura, K.10
-
6
-
-
0343181431
-
The hematopoietic-specific adaptor protein gads functions in T-cell signaling via interactions with the SLP-76 and LAT adaptors
-
S. K. Liu, N. Fang, G. A. Koretzky, C. J. McGlade, The hematopoietic-specific adaptor protein gads functions in T-cell signaling via interactions with the SLP-76 and LAT adaptors. Curr. Biol. 9, 67-75 (1999).
-
(1999)
Curr. Biol.
, vol.9
, pp. 67-75
-
-
Liu, S.K.1
Fang, N.2
Koretzky, G.A.3
McGlade, C.J.4
-
7
-
-
0033538574
-
The immunological synapse: A molecular machine controlling T cell activation
-
DOI 10.1126/science.285.5425.221
-
A. Grakoui, S. K. Bromley, C. Sumen, M. M. Davis, A. S. Shaw, P. M. Allen, M. L. Dustin, The immunological synapse: A molecular machine controlling T cell activation. Science 285, 221-227 (1999). (Pubitemid 29329988)
-
(1999)
Science
, vol.285
, Issue.5425
, pp. 221-227
-
-
Grakoui, A.1
Bromley, S.K.2
Sumen, C.3
Davis, M.M.4
Shaw, A.S.5
Allen, P.M.6
Dustin, M.L.7
-
8
-
-
0032480279
-
Three-dimensional segregation of supramolecular activation clusters in T cells
-
C. R. Monks, B. A. Freiberg, H. Kupfer, N. Sciaky, A. Kupfer, Three-dimensional segregation of supramolecular activation clusters in T cells. Nature 395, 82-86 (1998).
-
(1998)
Nature
, vol.395
, pp. 82-86
-
-
Monks, C.R.1
Freiberg, B.A.2
Kupfer, H.3
Sciaky, N.4
Kupfer, A.5
-
9
-
-
0033593045
-
The human natural killer cell immune synapse
-
D. M. Davis, I. Chiu, M. Fassett, G. B. Cohen, O. Mandelboim, J. L. Strominger, The human natural killer cell immune synapse. Proc. Natl. Acad. Sci. U. S. A. 96, 15062-15067 (1999).
-
(1999)
Proc. Natl. Acad. Sci. U. S. A
, vol.96
, pp. 15062-15067
-
-
Davis, D.M.1
Chiu, I.2
Fassett, M.3
Cohen, G.B.4
Mandelboim, O.5
Strominger, J.L.6
-
10
-
-
0035942781
-
B cells acquire antigen from target cells after synapse formation
-
F. D. Batista, D. Iber, M. S. Neuberger, B cells acquire antigen from target cells after synapse formation. Nature 411, 489-494 (2001).
-
(2001)
Nature
, vol.411
, pp. 489-494
-
-
Batista, F.D.1
Iber, D.2
Neuberger, M.S.3
-
11
-
-
12344272845
-
Dynamic molecular interactions linking the T cell antigen receptor to the actin cytoskeleton
-
M. Barda-Saad, A. Braiman, R. Titerence, S. C. Bunnell, V. A. Barr, L. E. Samelson, Dynamic molecular interactions linking the T cell antigen receptor to the actin cytoskeleton. Nat. Immunol. 6, 80-89 (2005).
-
(2005)
Nat. Immunol.
, vol.6
, pp. 80-89
-
-
Barda-Saad, M.1
Braiman, A.2
Titerence, R.3
Bunnell, S.C.4
Barr, V.A.5
Samelson, L.E.6
-
12
-
-
33746962713
-
T-cell antigen receptor-induced signaling complexes: Internalization via a cholesterol-dependent endocytic pathway
-
V. A. Barr, L. Balagopalan, M. Barda-Saad, R. Polishchuk, H. Boukari, S. C. Bunnell, K. M. Bernot, Y. Toda, R. Nossal, L. E. Samelson, T-cell antigen receptor-induced signaling complexes: Internalization via a cholesterol- dependent endocytic pathway. Traffic 7, 1143-1162 (2006).
-
(2006)
Traffic
, vol.7
, pp. 1143-1162
-
-
Barr, V.A.1
Balagopalan, L.2
Barda-Saad, M.3
Polishchuk, R.4
Boukari, H.5
Bunnell, S.C.6
Bernot, K.M.7
Toda, Y.8
Nossal, R.9
Samelson, L.E.10
-
13
-
-
33749171235
-
Persistence of cooperatively stabilized signaling clusters drives T-cell activation
-
S. C. Bunnell, A. L. Singer, D. I. Hong, B. H. Jacque, M. S. Jordan, M. C. Seminario, V. A. Barr, G. A. Koretzky, L. E. Samelson, Persistence of cooperatively stabilized signaling clusters drives T-cell activation. Mol. Cell. Biol. 26, 7155-7166 (2006).
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 7155-7166
-
-
Bunnell, S.C.1
Singer, A.L.2
Hong, D.I.3
Jacque, B.H.4
Jordan, M.S.5
Seminario, M.C.6
Barr, V.A.7
Koretzky, G.A.8
Samelson, L.E.9
-
14
-
-
33746011209
-
T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster
-
R. Varma, G. Campi, T. Yokosuka, T. Saito, M. L. Dustin, T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster. Immunity 25, 117-127 (2006).
-
(2006)
Immunity
, vol.25
, pp. 117-127
-
-
Varma, R.1
Campi, G.2
Yokosuka, T.3
Saito, T.4
Dustin, M.L.5
-
15
-
-
30044441433
-
Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76
-
T. Yokosuka, K. Sakata-Sogawa, W. Kobayashi, M. Hiroshima, A. Hashimoto-Tane, M. Tokunaga, M. L. Dustin, T. Saito, Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76. Nat. Immunol. 6, 1253-1262 (2005).
-
(2005)
Nat. Immunol.
, vol.6
, pp. 1253-1262
-
-
Yokosuka, T.1
Sakata-Sogawa, K.2
Kobayashi, W.3
Hiroshima, M.4
Hashimoto-Tane, A.5
Tokunaga, M.6
Dustin, M.L.7
Saito, T.8
-
16
-
-
27544441784
-
Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling
-
G. Campi, R. Varma, M. L. Dustin, Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling. J. Exp. Med. 202, 1031-1036 (2005).
-
(2005)
J. Exp. Med.
, vol.202
, pp. 1031-1036
-
-
Campi, G.1
Varma, R.2
Dustin, M.L.3
-
17
-
-
0037144842
-
T cell receptor ligation induces the formation of dynamically regulated signaling assemblies
-
S. C. Bunnell, D. I. Hong, J. R. Kardon, T. Yamazaki, C. J. McGlade, V. A. Barr, L. E. Samelson, T cell receptor ligation induces the formation of dynamically regulated signaling assemblies. J. Cell Biol. 158, 1263-1275 (2002).
-
(2002)
J. Cell. Biol.
, vol.158
, pp. 1263-1275
-
-
Bunnell, S.C.1
Hong, D.I.2
Kardon, J.R.3
Yamazaki, T.4
McGlade, C.J.5
Barr, V.A.6
Samelson, L.E.7
-
18
-
-
33745861018
-
Microclusters of inhibitory killer immunoglobulin-like receptor signaling at natural killer cell immunological synapses
-
B. Treanor, P. M. Lanigan, S. Kumar, C. Dunsby, I. Munro, E. Auksorius, F. J. Culley, M. A. Purbhoo, D. Phillips, M. A. Neil, D. N. Burshtyn, P. M. French, D. M. Davis, Microclusters of inhibitory killer immunoglobulin-like receptor signaling at natural killer cell immunological synapses. J. Cell Biol. 174, 153-161 (2006).
-
(2006)
J. Cell. Biol.
, vol.174
, pp. 153-161
-
-
Treanor, B.1
Lanigan, P.M.2
Kumar, S.3
Dunsby, C.4
Munro, I.5
Auksorius, E.6
Culley, F.J.7
Purbhoo, M.A.8
Phillips, D.9
Neil, M.A.10
Burshtyn, D.N.11
French, P.M.12
Davis, D.M.13
-
19
-
-
68049118970
-
Natural killer cell signal integration balances synapse symmetry and migration
-
F. J. Culley, M. Johnson, J. H. Evans, S. Kumar, R. Crilly, J. Casasbuenas, T. Schnyder, M. Mehrabi, M. P. Deonarain, D. S. Ushakov, V. Braud, G. Roth, R. Brock, K. Köhler, D. M. Davis, Natural killer cell signal integration balances synapse symmetry and migration. PLoS Biol. 7, e1000159 (2009).
-
(2009)
PLoS Biol.
, vol.7
-
-
Culley, F.J.1
Johnson, M.2
Evans, J.H.3
Kumar, S.4
Crilly, R.5
Casasbuenas, J.6
Schnyder, T.7
Mehrabi, M.8
Deonarain, M.P.9
Ushakov, D.S.10
Braud, V.11
Roth, G.12
Brock, R.13
Köhler, K.14
Davis, D.M.15
-
20
-
-
58149280494
-
High-speed high-resolution imaging of intercellular immune synapses using optical tweezers
-
S. Oddos, C. Dunsby, M. A. Purbhoo, A. Chauveau, D. M. Owen, M. A. Neil, D. M. Davis, P. M. French, High-speed high-resolution imaging of intercellular immune synapses using optical tweezers. Biophys. J. 95, L66-L68 (2008).
-
(2008)
Biophys. J.
, vol.95
-
-
Oddos, S.1
Dunsby, C.2
Purbhoo, M.A.3
Chauveau, A.4
Owen, D.M.5
Neil, M.A.6
Davis, D.M.7
French, P.M.8
-
21
-
-
0033638003
-
On the dynamics of TCR:CD3 complex cell surface expression and downmodulation
-
H. Liu, M. Rhodes, D. L. Wiest, D. A. Vignali, On the dynamics of TCR:CD3 complex cell surface expression and downmodulation. Immunity 13, 665-675 (2000).
-
(2000)
Immunity
, vol.13
, pp. 665-675
-
-
Liu, H.1
Rhodes, M.2
Wiest, D.L.3
Vignali, D.A.4
-
22
-
-
11144354114
-
Dynamic recruitment of the adaptor protein LAT: LAT exists in two distinct intracellular pools and controls its own recruitment
-
G. Bonello, N. Blanchard, M. C. Montoya, E. Aguado, C. Langlet, H. T. He, S. Nunez-Cruz, M. Malissen, F. Sanchez-Madrid, D. Olive, C. Hivroz, Y. Collette, Dynamic recruitment of the adaptor protein LAT: LAT exists in two distinct intracellular pools and controls its own recruitment. J. Cell Sci. 117, 1009-1016 (2004).
-
(2004)
J. Cell. Sci.
, vol.117
, pp. 1009-1016
-
-
Bonello, G.1
Blanchard, N.2
Montoya, M.C.3
Aguado, E.4
Langlet, C.5
He, H.T.6
Nunez-Cruz, S.7
Malissen, M.8
Sanchez-Madrid, F.9
Olive, D.10
Hivroz, C.11
Collette, Y.12
-
23
-
-
0036172558
-
Role of ICAM-3 in the initial interaction of T lymphocytes and APCs
-
M. C. Montoya, D. Sancho, G. Bonello, Y. Collette, C. Langlet, H. T. He, P. Aparicio, A. Alcover, D. Olive, F. Sanchez-Madrid, Role of ICAM-3 in the initial interaction of T lymphocytes and APCs. Nat. Immunol. 3, 159-168 (2002).
-
(2002)
Nat. Immunol.
, vol.3
, pp. 159-168
-
-
Montoya, M.C.1
Sancho, D.2
Bonello, G.3
Collette, Y.4
Langlet, C.5
He, H.T.6
Aparicio, P.7
Alcover, A.8
Olive, D.9
Sanchez-Madrid, F.10
-
24
-
-
37549071047
-
C-Cbl mediated regulation of LAT-nucleated signaling complexes
-
L. Balagopalan, V. A. Barr, C. L. Sommers, M. Barda-Saad, A. Goyal, M. S. Isakowitz, L. E. Samelson, c-Cbl mediated regulation of LAT-nucleated signaling complexes. Mol. Cell. Biol. 27, 8622-8636 (2007).
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 8622-8636
-
-
Balagopalan, L.1
Barr, V.A.2
Sommers, C.L.3
Barda-Saad, M.4
Goyal, A.5
Isakowitz, M.S.6
Samelson, L.E.7
-
25
-
-
0034725625
-
Association of Grb2, Gads, and phospholipase C-g1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell antigen receptor-mediated signaling
-
W. Zhang, R. P. Trible, M. Zhu, S. K. Liu, C. J. McGlade, L. E. Samelson, Association of Grb2, Gads, and phospholipase C-g1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell antigen receptor-mediated signaling. J. Biol. Chem. 275, 23355-23361 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 23355-23361
-
-
Zhang, W.1
Trible, R.P.2
Zhu, M.3
Liu, S.K.4
McGlade, C.J.5
Samelson, L.E.6
-
26
-
-
44649191160
-
T cell costimulation via the integrin VLA-4 inhibits the actin-dependent centralization of signaling microclusters containing the adaptor SLP-76
-
K. Nguyen, N. R. Sylvain, S. C. Bunnell, T cell costimulation via the integrin VLA-4 inhibits the actin-dependent centralization of signaling microclusters containing the adaptor SLP-76. Immunity 28, 810-821 (2008).
-
(2008)
Immunity
, vol.28
, pp. 810-821
-
-
Nguyen, K.1
Sylvain, N.R.2
Bunnell, S.C.3
-
27
-
-
20444404267
-
Single-molecule microscopy reveals plasma membrane microdomains created by protein-protein networks that exclude or trap signaling molecules in T cells
-
A. D. Douglass, R. D. Vale, Single-molecule microscopy reveals plasma membrane microdomains created by protein-protein networks that exclude or trap signaling molecules in T cells. Cell 121, 937-950 (2005).
-
(2005)
Cell.
, vol.121
, pp. 937-950
-
-
Douglass, A.D.1
Vale, R.D.2
-
28
-
-
0030819308
-
A common inhibitory receptor for major histocompatibility complex class I molecules on human lymphoid and myelomonocytic cells
-
M. Colonna, F. Navarro, T. Bellón, M. Llano, P. Garcia, J. Samaridis, L. Angman, M. Cella, M. López-Botet, A common inhibitory receptor for major histocompatibility complex class I molecules on human lymphoid and myelomonocytic cells. J. Exp. Med. 186, 1809-1818 (1997).
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1809-1818
-
-
Colonna, M.1
Navarro, F.2
Bellón, T.3
Llano, M.4
Garcia, P.5
Samaridis, J.6
Angman, L.7
Cella, M.8
López-Botet, M.9
-
29
-
-
0035865379
-
Ig-like transcript 2 (ILT2)/leukocyte Ig-like receptor 1 (LIR1) inhibits TCR signaling and actin cytoskeleton reorganization
-
J. Dietrich, M. Cella, M. Colonna, Ig-like transcript 2 (ILT2)/leukocyte Ig-like receptor 1 (LIR1) inhibits TCR signaling and actin cytoskeleton reorganization. J. Immunol. 166, 2514-2521 (2001).
-
(2001)
J. Immunol.
, vol.166
, pp. 2514-2521
-
-
Dietrich, J.1
Cella, M.2
Colonna, M.3
-
30
-
-
38349074305
-
CTLA-4 disrupts ZAP70 microcluster formation with reduced T cell/APC dwell times and calcium mobilization
-
H. Schneider, X. Smith, H. Liu, G. Bismuth, C. E. Rudd, CTLA-4 disrupts ZAP70 microcluster formation with reduced T cell/APC dwell times and calcium mobilization. Eur. J. Immunol. 38, 40-47 (2008).
-
(2008)
Eur. J. Immunol.
, vol.38
, pp. 40-47
-
-
Schneider, H.1
Smith, X.2
Liu, H.3
Bismuth, G.4
Rudd, C.E.5
-
31
-
-
70350414453
-
Organization of proximal signal initiation at the TCR:CD3 complex
-
C. S. Guy, D. A. Vignali, Organization of proximal signal initiation at the TCR:CD3 complex. Immunol. Rev. 232, 7-21 (2009).
-
(2009)
Immunol. Rev.
, vol.232
, pp. 7-21
-
-
Guy, C.S.1
Vignali, D.A.2
-
32
-
-
0035817631
-
High resolution mapping of mast cell membranes reveals primary and secondary domains of Fc0RI and LAT
-
B. S. Wilson, J. R. Pfeiffer, Z. Surviladze, E. A. Gaudet, J. M. Oliver, High resolution mapping of mast cell membranes reveals primary and secondary domains of Fc0RI and LAT. J. Cell Biol. 154, 645-658 (2001).
-
(2001)
J. Cell. Biol.
, vol.154
, pp. 645-658
-
-
Wilson, B.S.1
Pfeiffer, J.R.2
Surviladze, Z.3
Gaudet, E.A.4
Oliver, J.M.5
-
33
-
-
74049157769
-
TCR and Lat are expressed on separate protein islands on T cell membranes and concatenate during activation
-
B. F. Lillemeier, M. A. Mortelmaier, M. B. Forstner, J. B. Huppa, J. T. Groves, M. M. Davis, TCR and Lat are expressed on separate protein islands on T cell membranes and concatenate during activation. Nat. Immunol. 11, 90-96 (2010).
-
(2010)
Nat. Immunol.
, vol.11
, pp. 90-96
-
-
Lillemeier, B.F.1
Mortelmaier, M.A.2
Forstner, M.B.3
Huppa, J.B.4
Groves, J.T.5
Davis, M.M.6
-
34
-
-
17844364513
-
Paradigm shift of the plasma membrane concept from the two-dimensional continuum fluid to the partitioned fluid: High-speed single-molecule tracking of membrane molecules
-
A. Kusumi, C. Nakada, K. Ritchie, K. Murase, K. Suzuki, H. Murakoshi, R. S. Kasai, J. Kondo, T. Fujiwara, Paradigm shift of the plasma membrane concept from the two-dimensional continuum fluid to the partitioned fluid: High-speed single-molecule tracking of membrane molecules. Annu. Rev. Biophys. Biomol. Struct. 34, 351-378 (2005).
-
(2005)
Annu. Rev. Biophys. Biomol. Struct.
, vol.34
, pp. 351-378
-
-
Kusumi, A.1
Nakada, C.2
Ritchie, K.3
Murase, K.4
Suzuki, K.5
Murakoshi, H.6
Kasai, R.S.7
Kondo, J.8
Fujiwara, T.9
-
35
-
-
75749096347
-
The endocytic matrix
-
G. Scita, P. P. Di Fiore, The endocytic matrix. Nature 463, 464-473 (2010).
-
(2010)
Nature
, vol.463
, pp. 464-473
-
-
Scita, G.1
Di Fiore, P.P.2
|