Phospholipase C-γ2 and Vav cooperate within signaling microclusters to propagate B cell spreading in response to membrane-bound antigen

Journal of Experimental Medicine

Volumn 205, Issue 4, 2008, Pages 853-868

  Weber, Michele ^a   Treanor, Bebhinn ^a   Depoil, David ^a   Shinohara, Hisaaki ^b   Harwood, Naomi E ^a   Hikida, Masaki ^b   Kurosaki, Tomohiro ^b   Batista, Facundo D ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b RIKEN Center for Integrative Medical Sciences   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR; BRUTON TYROSINE KINASE; MEMBRANE ANTIGEN; PHOSPHOLIPASE C GAMMA2; PROTEIN KINASE LYN; PROTEIN KINASE SYK; VAV PROTEIN; ANTIGEN; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; LYN PROTEIN-TYROSINE KINASE; PHOSPHOLIPASE C GAMMA; PROTEIN TYROSINE KINASE; SIGNAL PEPTIDE;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CELL ACTIVATION; CELL SPREADING; CONTROLLED STUDY; FLUORESCENCE MICROSCOPY; GENE AMPLIFICATION; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; SIGNAL TRANSDUCTION; ANIMAL; BIOLOGICAL MODEL; CELL MEMBRANE; CELL MOTION; CHICKEN; CYTOLOGY; ENZYMOLOGY; METABOLISM; PROTEIN BINDING; RAT;

ANIMALS; ANTIGENS; B-LYMPHOCYTES; CELL MEMBRANE; CELL MOVEMENT; CHICKENS; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MODELS, BIOLOGICAL; PHOSPHOLIPASE C GAMMA; PROTEIN BINDING; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS C-VAV; RATS; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES;

EID: 42249090333     PISSN: 00221007     EISSN: 00221007     Source Type: Journal    
DOI: 10.1084/jem.20072619     Document Type: Article

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