-
1
-
-
0026770377
-
Integrins: Versatility, modulation, and signaling in cell adhesion
-
Hynes RO. Integrins: versatility, modulation, and signaling in cell adhesion. Cell. 1992;69:11-25.
-
(1992)
Cell
, vol.69
, pp. 11-25
-
-
Hynes, R.O.1
-
2
-
-
34247891506
-
Structural basis of integrin regulation and signaling
-
DOI 10.1146/annurev.immunol.25.022106.141618
-
Luo BH, Carman CV, Springer TA. Structural basis of integrin regulation and signaling. Annu Rev Immunol. 2007;25:619-647. (Pubitemid 46697919)
-
(2007)
Annual Review of Immunology
, vol.25
, pp. 619-647
-
-
Luo, B.-H.1
Carman, C.V.2
Springer, T.A.3
-
4
-
-
4344691642
-
Membranes as messengers in T cell adhesion signalling
-
DOI 10.1038/ni1057
-
Dustin ML, Bivona TG, Philips MR. Membranes as messengers in T cell adhesion signaling. Nat Immunol. 2004;5:363-372. (Pubitemid 38500084)
-
(2004)
Nature Immunology
, vol.5
, Issue.4
, pp. 363-372
-
-
Dustin, M.L.1
Bivona, T.G.2
Philips, M.R.3
-
6
-
-
44149105411
-
Kindlin-2 controls bidirectional signaling of integrins
-
DOI 10.1101/gad.469408
-
Montanez E, Ussar S, Schifferer M, et al. Kindlin-2 controls bidirectional signaling of integrins. Genes Dev. 2008;22:1325-1330. (Pubitemid 351717522)
-
(2008)
Genes and Development
, vol.22
, Issue.10
, pp. 1325-1330
-
-
Montanez, E.1
Ussar, S.2
Schifferer, M.3
Bosl, M.4
Zent, R.5
Moser, M.6
Fassler, R.7
-
7
-
-
40449133970
-
Kindlin-3 is essential for integrin activation and platelet aggregation
-
DOI 10.1038/nm1722, PII NM1722
-
Moser M, Nieswandt B, Ussar S, Pozgajova M, Fassler R. Kindlin-3 is essential for integrin activation and platelet aggregation. Nat Med. 2008;14:325-330. (Pubitemid 351347914)
-
(2008)
Nature Medicine
, vol.14
, Issue.3
, pp. 325-330
-
-
Moser, M.1
Nieswandt, B.2
Ussar, S.3
Pozgajova, M.4
Fassler, R.5
-
8
-
-
66449119343
-
Kindlin-1 and -2 directly bind the C-terminal region of β integrin cytoplasmic tails and exert integrin-specific activation effects
-
Harburger DS, Bouaouina M, Calderwood DA. Kindlin-1 and -2 directly bind the C-terminal region of β integrin cytoplasmic tails and exert integrin-specific activation effects. J Biol Chem. 2009;284:11485-11497.
-
(2009)
J Biol Chem
, vol.284
, pp. 11485-11497
-
-
Harburger, D.S.1
Bouaouina, M.2
Calderwood, D.A.3
-
9
-
-
61949352480
-
2 integrin-mediated leukocyte adhesion to endothelial cells
-
2 integrin-mediated leukocyte adhesion to endothelial cells. Nat Med. 2009;15:300-305.
-
(2009)
Nat Med
, vol.15
, pp. 300-305
-
-
Moser, M.1
Bauer, M.2
Schmid, S.3
-
10
-
-
47549099572
-
SILAC Mouse for Quantitative Proteomics Uncovers Kindlin-3 as an Essential Factor for Red Blood Cell Function
-
DOI 10.1016/j.cell.2008.05.033, PII S0092867408006958
-
Krüger M, Moser M, Ussar S, et al. SILAC mouse for quantitative proteomics uncovers kindlin-3 as an essential factor for red blood cell function. Cell. 2008;134:353-364. (Pubitemid 352010327)
-
(2008)
Cell
, vol.134
, Issue.2
, pp. 353-364
-
-
Kruger, M.1
Moser, M.2
Ussar, S.3
Thievessen, I.4
Luber, C.A.5
Forner, F.6
Schmidt, S.7
Zanivan, S.8
Fassler, R.9
Mann, M.10
-
11
-
-
0141670816
-
LAD-III, a novel group of leukocyte integrin activation deficiencies
-
DOI 10.1016/j.it.2003.08.001
-
Alon R, Etzioni A. LAD-III, a novel group of leukocyte integrin activation deficiencies. Trends Immunol. 2003;24:561-566. (Pubitemid 37205208)
-
(2003)
Trends in Immunology
, vol.24
, Issue.10
, pp. 561-566
-
-
Alon, R.1
Etzioni, A.2
-
12
-
-
34447255182
-
A LAD-III syndrome is associated with defective expression of the Rap-1 activator CalDAG-GEFI in lymphocytes, neutrophils, and platelets
-
DOI 10.1084/jem.20070058
-
Pasvolsky R, Feigelson SW, Kilic SS, et al. A LAD-III syndrome is associated with defective expression of the Rap-1 activator CalDAG-GEFI in lymphocytes, neutrophils, and platelets. J Exp Med. 2007;204:1571-1582. (Pubitemid 47048024)
-
(2007)
Journal of Experimental Medicine
, vol.204
, Issue.7
, pp. 1571-1582
-
-
Pasvolsky, R.1
Feigelson, S.W.2
Kilic, S.S.3
Simon, A.J.4
Tal-Lapidot, G.5
Grabovsky, V.6
Crittenden, J.R.7
Amariglio, N.8
Safran, M.9
Graybiel, A.M.10
Rechavi, G.11
Ben-Dor, S.12
Etzioni, A.13
Alon, R.14
-
13
-
-
55249083592
-
Kindlin-3: A new gene involved in the pathogenesis of LAD-III
-
Mory A, Feigelson SW, Yarali N, et al. Kindlin-3: a new gene involved in the pathogenesis of LAD-III. Blood. 2008;112:2591.
-
(2008)
Blood
, vol.112
, pp. 2591
-
-
Mory, A.1
Feigelson, S.W.2
Yarali, N.3
-
14
-
-
66549121768
-
LAD-1/Variant syndrome is caused by mutations in FERMT3
-
Kuijpers TW, van de Vijver E, Weterman MA, et al. LAD-1/Variant syndrome is caused by mutations in FERMT3. Blood. 2009;113:4740-4746.
-
(2009)
Blood
, vol.113
, pp. 4740-4746
-
-
Kuijpers, T.W.1
Van De Vijver, E.2
Weterman, M.A.3
-
15
-
-
61949240364
-
A point mutation in KINDLIN3 ablates activation of three integrin subfamilies in humans
-
Malinin NL, Zhang L, Choi J, et al. A point mutation in KINDLIN3 ablates activation of three integrin subfamilies in humans. Nat Med. 2009;15:313-318.
-
(2009)
Nat Med
, vol.15
, pp. 313-318
-
-
Malinin, N.L.1
Zhang, L.2
Choi, J.3
-
16
-
-
61949086409
-
Leukocyte adhesion deficiency-III is caused by mutations in KINDLIN3 affecting integrin activation
-
Svensson L, Howarth K, McDowall A, et al. Leukocyte adhesion deficiency-III is caused by mutations in KINDLIN3 affecting integrin activation. Nat Med. 2009;15:306-312.
-
(2009)
Nat Med
, vol.15
, pp. 306-312
-
-
Svensson, L.1
Howarth, K.2
McDowall, A.3
-
18
-
-
0027398448
-
A subpopulation of Mac-1 (CD11b/CD18) molecules mediates neutrophil adhesion to ICAM-1 and fibrinogen
-
DOI 10.1083/jcb.120.2.545
-
Diamond MS, Springer TA. A subpopulation of Mac-1 (CD11b/CD18) molecules mediates neutrophil adhesion to ICAM-1 and fibrinogen. J Cell Biol. 1993;120:545-556. (Pubitemid 23040092)
-
(1993)
Journal of Cell Biology
, vol.120
, Issue.2
, pp. 545-556
-
-
Diamond, M.S.1
Springer, T.A.2
-
19
-
-
0035576186
-
CD18 activation epitopes induced by leukocyte activation
-
Beals CR, Edwards AC, Gottschalk RJ, Kuijpers TW, Staunton DE. CD18 activation epitopes induced by leukocyte activation. J Immunol. 2001;167:6113-6122.
-
(2001)
J Immunol
, vol.167
, pp. 6113-6122
-
-
Beals, C.R.1
Edwards, A.C.2
Gottschalk, R.J.3
Kuijpers, T.W.4
Staunton, D.E.5
-
20
-
-
0036220127
-
Cysteine-rich module structure reveals a fulcrum for integrin rearrangement upon activation
-
DOI 10.1038/nsb779
-
Beglova N, Blacklow SC, Takagi J, Springer TA. Cysteine-rich module structure reveals a fulcrum for integrin rearrangement upon activation. Nat Struct Biol. 2002;9:282-287. (Pubitemid 34289901)
-
(2002)
Nature Structural Biology
, vol.9
, Issue.4
, pp. 282-287
-
-
Beglova, N.1
Blacklow, S.C.2
Takagi, J.3
Springer, T.A.4
-
21
-
-
0034204188
-
1-integrin activation is necessary for high-efficiency T-cell subset interactions with VCAM-1 under flow
-
1-integrin activation is necessary for high-efficiency T-cell subset interactions with VCAM-1 under flow. Microcirculation. 2000;7:201-214.
-
(2000)
Microcirculation
, vol.7
, pp. 201-214
-
-
Lim, Y.C.1
Wakelin, M.W.2
Henault, L.3
-
22
-
-
0034698511
-
4 integrin clustering by immobilized chemokines enhances leukocyte capture and rolling under flow prior to firm adhesion to endothelium
-
4 integrin clustering by immobilized chemokines enhances leukocyte capture and rolling under flow prior to firm adhesion to endothelium. J Exp Med. 2000;192:495-505.
-
(2000)
J Exp Med
, vol.192
, pp. 495-505
-
-
Grabovsky, V.1
Feigelson, S.2
Chen, C.3
-
26
-
-
0026794668
-
The mutational spectrum of single base-pair substitutions in mRNA splice junctions of human genes: Causes and consequences
-
Krawczak M, Reiss J, Cooper DN. The mutational spectrum of single base-pair substitutions in mRNA splice junctions of human genes: causes and consequences. Hum Genet. 1992;90:41-54.
-
(1992)
Hum Genet
, vol.90
, pp. 41-54
-
-
Krawczak, M.1
Reiss, J.2
Cooper, D.N.3
-
27
-
-
18244364123
-
Lymphocyte arrest requires instantaneous induction of an extended LFA-1 conformation mediated by endothelium-bound chemokines
-
DOI 10.1038/ni1194
-
Shamri R, Grabovsky V, Gauguet JM, et al. Lymphocyte arrest requires instantaneous induction of an extended LFA-1 conformation mediated by endothelium-bound chemokines. Nat Immunol. 2005;6:497-506. (Pubitemid 41716763)
-
(2005)
Nature Immunology
, vol.6
, Issue.5
, pp. 497-506
-
-
Shamri, R.1
Grabovsky, V.2
Gauguet, J.-M.3
Feigelson, S.4
Manevich, E.5
Kolanus, W.6
Robinson, M.K.7
Staunton, D.E.8
Von Andrian, U.H.9
Alon, R.10
-
28
-
-
58549086016
-
Regulation of conformer-specific activation of the integrin LFA-1 by a chemokine-triggered Rho signaling module
-
Bolomini-Vittori M, Montresor A, Giagulli C, et al. Regulation of conformer-specific activation of the integrin LFA-1 by a chemokine-triggered Rho signaling module. Nat Immunol. 2009;10:185-194.
-
(2009)
Nat Immunol
, vol.10
, pp. 185-194
-
-
Bolomini-Vittori, M.1
Montresor, A.2
Giagulli, C.3
-
29
-
-
0034507687
-
2 integrin affinity and mobility changes: Differential regulation and roles in lymphocyte arrest under flow
-
2 integrin affinity and mobility changes: differential regulation and roles in lymphocyte arrest under flow. Immunity. 2000;13:759-769.
-
(2000)
Immunity
, vol.13
, pp. 759-769
-
-
Constantin, G.1
Majeed, M.2
Giagulli, C.3
-
30
-
-
33846246384
-
Force as a Facilitator of Integrin Conformational Changes during Leukocyte Arrest on Blood Vessels and Antigen-Presenting Cells
-
DOI 10.1016/j.immuni.2007.01.002, PII S1074761307001021
-
Alon R, Dustin ML. Force as a facilitator of integrin conformational changes during leukocyte arrest on blood vessels and antigen-presenting cells. Immunity. 2007;26:17-27. (Pubitemid 46109349)
-
(2007)
Immunity
, vol.26
, Issue.1
, pp. 17-27
-
-
Alon, R.1
Dustin, M.L.2
-
31
-
-
33845566257
-
Importance of force linkage in mechanochemistry of adhesion receptors
-
DOI 10.1021/bi061566o
-
Astrof NS, Salas A, Shimaoka M, Chen J, Springer TA. Importance of force linkage in mechanochemistry of adhesion receptors. Biochemistry. 2006;45:15020-15028. (Pubitemid 44937014)
-
(2006)
Biochemistry
, vol.45
, Issue.50
, pp. 15020-15028
-
-
Astrof, N.S.1
Salas, A.2
Shimaoka, M.3
Chen, J.4
Springer, T.A.5
-
32
-
-
34548780292
-
Lymph node chemokines promote sustained T lymphocyte motility without triggering stable integrin adhesiveness in the absence of shear forces
-
DOI 10.1038/ni1499, PII NI1499
-
Woolf E, Grigorova I, Sagiv A, et al. Lymph node chemokines promote sustained T lymphocyte motility without triggering stable integrin adhesiveness in the absence of shear forces. Nat Immunol. 2007;8:1076-1085. (Pubitemid 47423755)
-
(2007)
Nature Immunology
, vol.8
, Issue.10
, pp. 1076-1085
-
-
Woolf, E.1
Grigorova, I.2
Sagiv, A.3
Grabovsky, V.4
Feigelson, S.W.5
Shulman, Z.6
Hartmann, T.7
Sixt, M.8
Cyster, J.G.9
Alon, R.10
-
33
-
-
34548495311
-
Talin 1 and paxillin facilitate distinct steps in rapid VLA-4-mediated adhesion strengthening to vascular cell adhesion molecule
-
DOI 10.1074/jbc.M700089200
-
Manevich E, Grabovsky V, Feigelson SW, Alon R. Talin 1 and paxillin facilitate distinct steps in rapid VLA-4-mediated adhesion strengthening to vascular cell adhesion molecule 1. J Biol Chem. 2007;282:25338-25348. (Pubitemid 47372824)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.35
, pp. 25338-25348
-
-
Manevich, E.1
Grabovsky, V.2
Feigelson, S.W.3
Alon, R.4
-
34
-
-
0031596163
-
1 integrin cytoplasmic domain sequences critical for integrin function
-
1 integrin cytoplasmic domain sequences critical for integrin function. Mol Biol Cell. 1998;9:2715-2727.
-
(1998)
Mol Biol Cell
, vol.9
, pp. 2715-2727
-
-
Romzek, N.C.1
Harris, E.S.2
Dell, C.L.3
-
36
-
-
57749116060
-
Structure of a complete integrin ectodomain in a physiologic resting state and activation and deactivation by applied forces
-
Zhu J, Luo BH, Xiao T, Zhang C, Nishida N, Springer TA. Structure of a complete integrin ectodomain in a physiologic resting state and activation and deactivation by applied forces. Mol Cell. 2008;32:849-861.
-
(2008)
Mol Cell
, vol.32
, pp. 849-861
-
-
Zhu, J.1
Luo, B.H.2
Xiao, T.3
Zhang, C.4
Nishida, N.5
Springer, T.A.6
-
38
-
-
0033539801
-
4 integrins modifies integrin-dependent biological responses
-
Liu S, Thomas SM, Woodside DG, et al. Binding of paxillin to α4 integrins modifies integrin-dependent biologic responses. Nature. 1999;402:676-681. (Pubitemid 129516339)
-
(1999)
Nature
, vol.402
, Issue.6762
, pp. 676-681
-
-
Liu, S.1
Thomas, S.M.2
Woodside, D.G.3
Rose, D.M.4
Klosses, W.B.5
Pfaff, M.6
Ginsberg, M.H.7
-
40
-
-
66149128873
-
The tail of integrins, talin, and kindlins
-
Moser M, Legate KR, Zent R, Fassler R. The tail of integrins, talin, and kindlins. Science. 2009;324:895-899.
-
(2009)
Science
, vol.324
, pp. 895-899
-
-
Moser, M.1
Legate, K.R.2
Zent, R.3
Fassler, R.4
-
42
-
-
61949212359
-
When integrins fail to integrate
-
Hidalgo A, Frenette PS. When integrins fail to integrate. Nat Med. 2009;15:249-250.
-
(2009)
Nat Med
, vol.15
, pp. 249-250
-
-
Hidalgo, A.1
Frenette, P.S.2
-
43
-
-
34249863368
-
Mice lacking the signaling molecule CalDAG-GEFI represent a model for leukocyte adhesion deficiency type III
-
DOI 10.1172/JCI30575
-
Bergmeier W, Goerge T, Wang H, et al. Mice lacking the signaling molecule CalDAG-GEFI represent a model for leukocyte adhesion deficiency type III. J Clin Invest. 2007;117:1699-1707. (Pubitemid 46871354)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.6
, pp. 1699-1707
-
-
Bergmeier, W.1
Goerge, T.2
Wang, H.-W.3
Crittenden, J.R.4
Baldwin, A.C.W.5
Cifuni, S.M.6
Housman, D.E.7
Graybiel, A.M.8
Wagner, D.D.9
-
44
-
-
36349034646
-
Essential role for Rap1 GTPase and its guanine exchange factor CalDAG-GEFI in LFA-1 but not VLA-4 integrin-mediated human T-cell adhesion
-
DOI 10.1182/blood-2007-03-077628
-
Ghandour H, Cullere X, Alvarez A, Luscinskas FW, Mayadas TN. Essential role for Rap1 GT-Pase and its guanine exchange factor CalDAG-GEFI in LFA-1 but not VLA-4 integrin mediated human T-cell adhesion. Blood. 2007;110:3682-3690. (Pubitemid 350159637)
-
(2007)
Blood
, vol.110
, Issue.10
, pp. 3682-3690
-
-
Ghandour, H.1
Cullere, X.2
Alvarez, A.3
Luscinskas, F.W.4
Mayadas, T.N.5
|