Natural Killer cell lytic granule secretion occurs through a pervasive actin network at the immune synapse

PLoS Biology

Volumn 9, Issue 9, 2011, Pages

  Rak, Gregory D ^a,b   Mace, Emily M ^b   Banerjee, Pinaki P ^b   Svitkina, Tatyana ^c   Orange, Jordan S ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1;

ACTIN FILAMENT; ARTICLE; CELL GRANULE; CELL INTERACTION; CELL LYTIC GRANULE; CELL MEMBRANE; CELL ORGANELLE; CELL SECRETION; CONTROLLED STUDY; CYTOTOXICITY; DEGRANULATION; HUMAN; HUMAN CELL; IMMUNOLOGICAL SYNAPSE; MICROSCOPY; NATURAL KILLER CELL; PERMEABILITY BARRIER; ALGORITHM; CELL LINE; CONFOCAL MICROSCOPY; ELECTRON MICROSCOPY; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GENETIC TRANSFECTION; GENETICS; IMAGE PROCESSING; LYMPHOCYTE ACTIVATION; METABOLISM; METHODOLOGY; MICROTUBULE ORGANIZING CENTER; PHYSIOLOGY; PLASMID; SECRETION; SECRETORY PATHWAY; SENSITIVITY AND SPECIFICITY; SIGNAL TRANSDUCTION; ULTRASTRUCTURE;

ACTINS; ALGORITHMS; CELL DEGRANULATION; CELL LINE; CELL MEMBRANE; FLOW CYTOMETRY; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMMUNOLOGICAL SYNAPSES; KILLER CELLS, NATURAL; LYMPHOCYTE ACTIVATION; LYSOSOMAL-ASSOCIATED MEMBRANE PROTEIN 1; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON; MICROSCOPY, FLUORESCENCE; MICROTUBULE-ORGANIZING CENTER; PLASMIDS; SECRETORY PATHWAY; SENSITIVITY AND SPECIFICITY; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 80053321288     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1001151     Document Type: Article

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