Organelle proteomics: Identification of the exocytic machinery associated with the natural killer cell secretory lysosome

Molecular and Cellular Proteomics

Volumn 6, Issue 5, 2007, Pages 767-780

  Casey, Tammy M ^a   Meade, Josephine L ^b   Hewitt, Eric W ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE PROTEIN; RAB PROTEIN; RAB27A PROTEIN; SNARE PROTEIN; SYNAPTOBREVIN; SYNAPTOBREVIN 7; TRITON X 114; UNCLASSIFIED DRUG;

ARTICLE; CELL FRACTIONATION; CELL ISOLATION; CELL ORGANELLE; CELL VACUOLE; CONTROLLED STUDY; ELECTROSPRAY MASS SPECTROMETRY; EXOCYTOSIS; HUMAN; HUMAN CELL; LIQUID CHROMATOGRAPHY; LYSOSOME; NATURAL KILLER CELL; NUCLEOTIDE SEQUENCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PREDICTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FAMILY; PROTEOMICS; SEPARATION TECHNIQUE; UNINDEXED SEQUENCE;

CELL LINE; CHROMATOGRAPHY, LIQUID; EXOCYTOSIS; KILLER CELLS, NATURAL; LYSOSOMES; PROTEOMICS; R-SNARE PROTEINS; RAB GTP-BINDING PROTEINS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 34249668425     PISSN: 15359476     EISSN: None     Source Type: Journal    
DOI: 10.1074/mcp.M600365-MCP200     Document Type: Article

References (46)

1. Trambas, C. M., and Griffiths, G. M. (2003) Delivering the kiss of death. Nat. Immunol. 4, 399-403
2. Davis, D. M., and Dustin, M. L. (2004) What is the importance of the immunological synapse? Trends Immunol. 25, 323-327
3. Trapani, J. A., and Smyth, M. J. (2002) Functional significance of the perforin/granzyme cell death pathway. Nat. Rev. Immunol. 2, 735-747
4. Blott, E. J., and Griffiths, G. M. (2002) Secretory lysosomes. Nat. Rev. Mol. Cell. Biol. 3, 122-131
5. Clark, R. H., Stinchcombe, J. C., Day, A., Blott, E., Booth, S., Bossi, G., Hamblin, T., Davies, E. G., and Griffiths, G. M. (2003) Adaptor protein 3-dependent microtubule-mediated movement of lytic granules to the immunological synapse. Nat. Immunol. 4, 1111-1120
6. Stinchcombe, J. C., Barral, D. C., Mules, E. H., Booth, S., Hume, A. N., Machesky, L. M., Seabra, M. C., and Griffiths, G. M. (2001) Rab27a is required for regulated secretion in cytotoxic T lymphocytes. J. Cell Biol. 152, 825-834
7. Haddad, E. K., Wu, X., Hammer, J. A., III, and Henkart, P. A. (2001) Defective granule exocytosis in Rab27a-deficient lymphocytes from Ashen mice. J. Cell Biol. 152, 835-842
8. Feldmann, J., Callebaut, I., Raposo, G., Certain, S., Bacq, D., Dumont, C., Lambert, N., Ouachee-Chardin, M., Chedeville, G., Tamary, H., Minard-Colin, V., Vilmer, E., Blanche, S., Le Deist, F., Fischer, A., and de Saint Basile, G. (2003) Munc 13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3). Cell 115, 461-473
9. Hong, W. (2005) SNAREs and traffic. Biochim. Biophys. Acta 1744, 493-517
10. Brunet, S., Thibault, P., Gagnon, E., Kearney, P., Bergeron, J. J., and Desjardins, M. (2003) Organelle proteomics: looking at less to see more. Trends Cell Biol. 13, 629-638
11. Stam, N. J., Spits, H., and Ploegh, H. L. (1986) Monoclonal antibodies raised against denatured HLA-B locus heavy chains permit biochemical characterization of certain HLA-C locus products. J. Immunol. 137, 2299-2306
12. Strom, M., Hume, A. N., Tarafder, A. K., Barkagianni, E., and Seabra, M. C. (2002) A family of Rab27-binding proteins. Melanophilin links Rab27a and myosin Va function in melanosome transport. J. Biol. Chem. 277, 25423-25430
13. Prekeris, R., Klumperman, J., and Scheller, R. H. (2000) Syntaxin 11 is an atypical SNARE abundant in the immune system. Eur. J. Cell Biol. 79, 771-780
14. Meade, J. L., de Wynter, E. A., Brett, P., Sharif, S. M., Woods, C. G., Markham, A. F., and Cook, G. P. (2006) A family with Papillon-Lefevre syndrome reveals a requirement for cathepsin C in granzyme B activation and NK cell cytolytic activity. Blood 107, 3665-3668
15. Beaufay, H., Amar-Costesec, A., Feytmans, E., Thines-Sempoux, D., Wibo, M., Robbi, M., and Berthet, J. (1974) Analytical study of microsomes and isolated subcellular membranes from rat liver. I. Biochemical methods. J Cell Biol. 61, 188-200
16. Bordier, C. (1981) Phase separation of integral membrane proteins in Triton X-114 solution. J Biol. Chem. 256, 1604-1607
17. Santoni, V., Molloy, M., and Rabilloud, T. (2000) Membrane proteins and proteomics: un amour impossible? Electrophoresis 21, 1054-1070
18. Casey, T. M., Arthur, P. G., and Bogoyevitch, M. A. (2005) Proteomic analysis reveals different protein changes during endothelin-1- or leukemic inhibitory factor-induced hypertrophy of cardiomyocytes in vitro. Mol. Cell. Proteomics 4, 651-661
19. Wilm, M., Shevchenko, A., Houthaeve, T., Breit, S., Schweigerer, L., Fotsis, T., and Mann, M. (1996) Femtomole sequencing of proteins from polyacrylamide gels by nano-electrospray mass spectrometry. Nature 379, 466-469
20. Sonnhammer, E. L., Eddy, S. R., Birney, E., Bateman, A., and Durbin, R. (1998) Pfam: multiple sequence alignments and HMM-profiles of protein domains. Nucleic Acids Res. 26, 320-322
21. Krogh, A., Larsson, B., von Heijne, G., and Sonnhammer, E. L. (2001) Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. J Mol. Biol. 305, 567-580
22. Peters, P. J., Borst, J., Oorschot, V., Fukuda, M., Krahenbuhl, O., Tschopp, J., Slot, J. W., and Geuze, H. J. (1991) Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes. J. Exo. Med. 173, 1099-1109
23. Garin, J., Diez, R., Kieffer, S., Dermine, J. F., Duclos, S., Gagnon, E., Sadoul, R., Rondeau, C., and Desjardins, M. (2001) The phagosome proteome: insight into phagosome functions. J. Cell Biol. 152, 165-180
24. Bell, A. W., Ward, M. A., Blackstock, W. P., Freeman, H. N., Choudhary, J. S., Lewis, A. P., Chotai, D., Fazel, A., Gushue, J. N., Paiement, J., Palcy, S., Chevet, E., Lafreniere-Roula, M., Solari, R., Thomas, D. Y., Rowley, A., and Bergeron, J. J. (2001) Proteomics characterization of abundant Golgi membrane proteins. J. Biol. Chem. 276, 5152-5165
25. Taylor, R. S., Wu, C. C., Hays, L. G., Eng, J. K., Yates, J. R., III, and Howell, K. E. (2000) Proteomics of rat liver Golgi complex: minor proteins are identified through sequential fractionation. Electrophoresis 21, 3441-3459
26. Moebius, J., Zahedi, R. P., Lewandrowski, U., Berger, C., Walter, U., and Sickmann, A. (2005) The human platelet membrane proteome reveals several new potential membrane proteins. Mol. Cell. Proteomics 4, 1754-1761
27. Sedelies, K. A., Sayers, T. J., Edwards, K. M., Chen, W., Pellicci, D. G., Godfrey, D. I., and Trapani, J. A. (2004) Discordant regulation of granzyme H and granzyme B expression in human lymphocytes. J. Biol. Chem. 279, 26581-26587
28. Carlsson, S. R., Roth, J., Piller, F., and Fukuda, M. (1988) Isolation and characterization of human lysosomal membrane glycoproteins, h-lamp-1 and h-lamp-2. Major sialoglycoproteins carrying polylactosaminoglycan. J. Biol. Chem. 263, 18911-18919
29. van Dam, E. M., and Robinson, P. J. (2006) Ral: mediator of membrane trafficking. Int. J. Biochem. Cell Biol. 38, 1841-1847
30. Chen, S., Liang, M. C., Chia, J. N., Ngsee, J. K., and Ting, A. E. (2001) Rab8b and its interacting partner TRIP8b are involved in regulated secretion in AtT20 cells. J. Biol. Chem. 276, 13209-13216
31. Wang, L., Li, G., and Sugita, S. (2004) RalA-exocyst interaction mediates GTP-dependent exocytosis. J. Biol. Chem. 279, 19875-19881
32. Vitale, N., Mawet, J., Camonis, J., Regazzi, R., Bader, M. F., and Chasserot-Golaz, S. (2005) The Small GTPase RalA controls exocytosis of large dense core secretory granules by interacting with ARF6-dependent phospholipase D1. J. Biol. Chem. 280, 29921-29928
33. Rao, S. K., Huynh, C., Proux-Gillardeaux, V., Galli, T., and Andrews, N. W. (2004) Identification of SNAREs involved in synaptotagmin VII-regulated lysosomal exocytosis. J. Biol. Chem. 279, 20471-20479
34. Pryor, P. R., Mullock, B. M., Bright, N. A., Lindsay, M. R., Gray, S. R., Richardson, S. C., Stewart, A., James, D. E., Piper, R. C., and Luzio, J. P. (2004) Combinatorial SNARE complexes with VAMP7 or VAMP8 define different late endocytic fusion events. EMBO Rep. 5, 590-595
35. Mullock, B. M., Smith, C. W., Ihrke, G., Bright, N. A., Lindsay, M., Parkinson, E. J., Brooks, D. A., Parton, R. G., James, D. E., Luzio, J. P., and Piper, R. C. (2000) Syntaxin 7 is localized to late endosome compartments, associates with Vamp 8, and is required for late endosome-lysosome fusion. Mol. Biol. Cell 11, 3137-3153
36. zur Stadt, U., Schmidt, S., Kasper, B., Beutel, K., Diler, A. S., Henter, J. I., Kabisch, H., Schneppenheim, R., Numberg, P., Janka, G., and Hennies, H. C. (2005) Linkage of familial hemophagocytic lymphohistiocytosis (FHL) type-4 to chromosome 6q24 and identification of mutations in syntaxin 11. Hum. Mol. Genet. 14, 827-834
37. Rudd, E., Goransdotter Ericson, K., Zheng, C., Uysal, Z., Ozkan, A., Gurgey, A., Fadeel, B., Nordenskjold, M., and Henter, J. I. (2006) Spectrum and clinical implications of syntaxin 11 gene mutations in familial haemophagocytic lymphohistiocytosis: association with disease-free remissions and haematopoetic malignancies. J. Med. Genet. 43, e14
38. Cuervo, A. M. (2004) Autophagy: in sickness and in health. Trends Cell Biol. 14, 70-77
39. Hicke, L., and Dunn, R. (2003) Regulation of membrane protein transport by ubiquitin and ubiquitin-binding proteins. Annu. Rev. Cell Dev. Biol. 19, 141-172
40. Bagshaw, R. D., Mahuran, D. J., and Callahan, J. W. (2005) A proteomic analysis of lysosomal integral membrane proteins reveals the diverse composition of the organelle. Mol. Cell. Proteomics, 4, 133-143
41. Hanna, J., Gonen-Gross, T., Fitchett, J., Rowe, T., Daniels, M., Amon, T. I., Gazit, R., Joseph, A., Schjetne, K. W., Steinle, A., Porgador, A., Mevorach, D., Goldman-Wohl, D., Yagel, S., LaBarre, M. J., Buckner, J. H., and Mandelboim, O. (2004) Novel APC-like properties of human NK cells directly regulate T cell activation. J. Clin. Investig. 114, 1612-1623
42. Watts, C. (1997) Capture and processing of exogenous antigens for presentation on MHC molecules. Annu. Rev. Immunol. 15, 821-850
43. Tsuboi, T., and Fukuda, M. (2006) Rab3A and Rab27A cooperatively regulate the docking step of dense-core vesicle exocytosis in PC12 cells. J. Cell Sci. 119, 2196-2203
44. 2+-regulated exocytosis of lysosomes. Cell 106, 157-169
45. Valdez, A. C., Cabaniols, J. P., Brown, M. J., and Roche, P. A. (1999) Syntaxin 11 is associated with SNAP-23 on late endosomes and the trans-Golgi network. J. Cell Sci. 112, 845-854
46. Tang, B. L., Low, D. Y., and Hong, W. (1998) Syntaxin 11: a member of the syntaxin family without a carboxyl terminal transmembrane domain. Biochem. Biophys. Res. Commun. 245, 627-632