Different NK cell-activating receptors preferentially recruit Rab27a or Munc13-4 to perforin-containing granules for cytotoxicity

Blood

Volumn 114, Issue 19, 2009, Pages 4117-4127

  Wood, Stephanie M ^a,b   Meeths, Marie ^a   Chiang, Samuel C C ^a   Bechensteen, Anne Grete ^c   Boelens, Jaap J ^d   Heilmann, Carsten ^e   Horiuchi, Hisanori ^f   Rosthøj, Steen ^g   Rutynowska, Olga ^h   Winiarski, Jacek ^a   Stow, Jennifer L ^b   Nordenskjöld, Magnus ^a   Henter, Jan Inge ^a   Ljunggren, Hans Gustaf ^a   Bryceson, Yenan T ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

^d UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^e Mental Health Services CPH   (Denmark)

^f KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^g AALBORG UNIVERSITY HOSPITAL   (Denmark)

^h CHILDREN'S MEMORIAL HEALTH INSTITUTE   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

IONOMYCIN; MUNC13 4 PROTEIN; MYOSIN; NATURAL KILLER CELL RECEPTOR; NATURAL KILLER CELL RECEPTOR NKG2D; PERFORIN; PHORBOL 13 ACETATE 12 MYRISTATE; RAB27A PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL MEDIATED CYTOTOXICITY; DEGRANULATION; GENE; GENE MUTATION; GRISCELLI SYNDROME; HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS; HUMAN; HUMAN CELL; NATURAL KILLER CELL; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAB27A GENE; UNC13D GENE;

EID: 72949100151     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2009-06-225359     Document Type: Article

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