-
1
-
-
79958205445
-
Sensing disease and danger: a survey of vertebrate PRRs and their origins
-
Hansen J.D., Vojtech L.N., Laing K.J. Sensing disease and danger: a survey of vertebrate PRRs and their origins. Dev Comp Immunol 2011, 35(9):886-897.
-
(2011)
Dev Comp Immunol
, vol.35
, Issue.9
, pp. 886-897
-
-
Hansen, J.D.1
Vojtech, L.N.2
Laing, K.J.3
-
2
-
-
78650694286
-
Toll-like receptors in innate immunity and infectious diseases
-
Wu M.H., Zang P., Huang X. Toll-like receptors in innate immunity and infectious diseases. Front Med in China 2010, 4(4):385-393.
-
(2010)
Front Med in China
, vol.4
, Issue.4
, pp. 385-393
-
-
Wu, M.H.1
Zang, P.2
Huang, X.3
-
3
-
-
73949127723
-
Pattern recognition receptor-dependent mechanisms of acute lung injury
-
Xiang M., Fan J. Pattern recognition receptor-dependent mechanisms of acute lung injury. Mol Med 2010, 16(1-2):69-82.
-
(2010)
Mol Med
, vol.16
, Issue.1-2
, pp. 69-82
-
-
Xiang, M.1
Fan, J.2
-
5
-
-
46249097190
-
What is idiosyncratic hepatotoxicity? What is it not?
-
Senior J.R. What is idiosyncratic hepatotoxicity? What is it not?. J Hepatol 2008, 47(6):1813-1815.
-
(2008)
J Hepatol
, vol.47
, Issue.6
, pp. 1813-1815
-
-
Senior, J.R.1
-
6
-
-
77249143567
-
Intrinsic versus idiosyncratic drug-induced hepatotoxicity-two villains or one?
-
Roth R.A., Ganey P.E. Intrinsic versus idiosyncratic drug-induced hepatotoxicity-two villains or one?. J Pharmacol Exp Ther 2010, 332(3):692-697.
-
(2010)
J Pharmacol Exp Ther
, vol.332
, Issue.3
, pp. 692-697
-
-
Roth, R.A.1
Ganey, P.E.2
-
7
-
-
32644474169
-
Acetaminophen-induced acute liver failure: results of a United States multicenter, prospective study
-
Larson A.M., Polson J., Fontana R.J., Davern T.J., Lalani E., Hynan L.S., et al. Acetaminophen-induced acute liver failure: results of a United States multicenter, prospective study. J Hepatol 2005, 42(6):1364-1372.
-
(2005)
J Hepatol
, vol.42
, Issue.6
, pp. 1364-1372
-
-
Larson, A.M.1
Polson, J.2
Fontana, R.J.3
Davern, T.J.4
Lalani, E.5
Hynan, L.S.6
-
8
-
-
3042738919
-
Acetaminophen and the U.S. Acute Liver Failure Study Group: lowering the risks of hepatic failure
-
Lee W.M. Acetaminophen and the U.S. Acute Liver Failure Study Group: lowering the risks of hepatic failure. J Hepatol 2004, 40(1):6-9.
-
(2004)
J Hepatol
, vol.40
, Issue.1
, pp. 6-9
-
-
Lee, W.M.1
-
9
-
-
79954615800
-
Current issues with acetaminophen hepatotoxicity-a clinically relevant model to test the efficacy of natural products
-
Jaeschke H., McGill M.R., Williams C.D., Ramachandran A. Current issues with acetaminophen hepatotoxicity-a clinically relevant model to test the efficacy of natural products. Life Sci 2011, 88(17-18):737-745.
-
(2011)
Life Sci
, vol.88
, Issue.17-18
, pp. 737-745
-
-
Jaeschke, H.1
McGill, M.R.2
Williams, C.D.3
Ramachandran, A.4
-
10
-
-
3042826208
-
Acetaminophen hepatotoxicity: what do we know, what don't we know, and what do we do next?
-
Kaplowitz N. Acetaminophen hepatotoxicity: what do we know, what don't we know, and what do we do next?. J Hepatol 2004, 40(1):23-26.
-
(2004)
J Hepatol
, vol.40
, Issue.1
, pp. 23-26
-
-
Kaplowitz, N.1
-
11
-
-
75349095405
-
The role of damage associated molecular pattern molecules in acetaminophen induced liver injury in mice
-
Martin-Murphy B.V., Holt M.P., Ju C. The role of damage associated molecular pattern molecules in acetaminophen induced liver injury in mice. Toxicol Lett 2010, 192(3):387-394.
-
(2010)
Toxicol Lett
, vol.192
, Issue.3
, pp. 387-394
-
-
Martin-Murphy, B.V.1
Holt, M.P.2
Ju, C.3
-
12
-
-
61749099391
-
Acetaminophen-induced hepatotoxicity in mice is dependent on Tlr9 and the Nalp3 inflammasome
-
Imaeda A.B., Watanabe A., Sohail M.A., Mahmood S., Mohamadnejad M., Sutterwala F.S., et al. Acetaminophen-induced hepatotoxicity in mice is dependent on Tlr9 and the Nalp3 inflammasome. J Clin Invest 2009, 119(2):305-314.
-
(2009)
J Clin Invest
, vol.119
, Issue.2
, pp. 305-314
-
-
Imaeda, A.B.1
Watanabe, A.2
Sohail, M.A.3
Mahmood, S.4
Mohamadnejad, M.5
Sutterwala, F.S.6
-
13
-
-
33646874825
-
Involvement of toll-like receptor 4 in acetaminophen hepatotoxicity
-
Yohe H.C., O'Hara K.A., Hunt J.A., Kitzmiller T.J., Wood S.G., Bement J.L., et al. Involvement of toll-like receptor 4 in acetaminophen hepatotoxicity. Am J Physiol-Gastrointest Liver Physiol 2006, 290(6):1269-1279.
-
(2006)
Am J Physiol-Gastrointest Liver Physiol
, vol.290
, Issue.6
, pp. 1269-1279
-
-
Yohe, H.C.1
O'Hara, K.A.2
Hunt, J.A.3
Kitzmiller, T.J.4
Wood, S.G.5
Bement, J.L.6
-
14
-
-
80051882006
-
Extracellular histones are mediators of death through TLR2 and TLR4 in mouse fatal liver injury
-
Xu J., Zhang X., Monestier M., Esmon N.L., Esmon C.T. Extracellular histones are mediators of death through TLR2 and TLR4 in mouse fatal liver injury. J Immunol 2011, 187(5):2626-2631.
-
(2011)
J Immunol
, vol.187
, Issue.5
, pp. 2626-2631
-
-
Xu, J.1
Zhang, X.2
Monestier, M.3
Esmon, N.L.4
Esmon, C.T.5
-
15
-
-
63149171602
-
CD24 and Siglec-10 selectively repress tissue damage-induced immune responses
-
Chen G.Y., Tang J., Zheng P., Liu Y. CD24 and Siglec-10 selectively repress tissue damage-induced immune responses. Science 2009, 323(5922):1722-1725.
-
(2009)
Science
, vol.323
, Issue.5922
, pp. 1722-1725
-
-
Chen, G.Y.1
Tang, J.2
Zheng, P.3
Liu, Y.4
-
16
-
-
80053075831
-
Cyclophilin A is a damage-associated molecular pattern molecule that mediates acetaminophen-induced liver injury
-
Dear J.W., Simpson K.J., Nicolai M.P., Catterson J.H., Street J., Huizinga T., et al. Cyclophilin A is a damage-associated molecular pattern molecule that mediates acetaminophen-induced liver injury. J Immunol 2011, 187(6):3347-3352.
-
(2011)
J Immunol
, vol.187
, Issue.6
, pp. 3347-3352
-
-
Dear, J.W.1
Simpson, K.J.2
Nicolai, M.P.3
Catterson, J.H.4
Street, J.5
Huizinga, T.6
-
17
-
-
0028096889
-
Kupffer cell stimulation with Cornybacterium parvum reduces some cytochrome P450-dependent activities and diminishes acetaminophen and carbon tetrachloride-induced liver injury in the rat
-
Raiford D.S., Thigpen M.C. Kupffer cell stimulation with Cornybacterium parvum reduces some cytochrome P450-dependent activities and diminishes acetaminophen and carbon tetrachloride-induced liver injury in the rat. Toxicol Appl Pharmacol 1994, 129(1):36-45.
-
(1994)
Toxicol Appl Pharmacol
, vol.129
, Issue.1
, pp. 36-45
-
-
Raiford, D.S.1
Thigpen, M.C.2
-
18
-
-
52449129584
-
Hepatic Mrp4 induction following acetaminophen exposure is dependent on Kupffer cell function
-
Campion S.N., Johnson R., Aleksunes L.M., Goedken M.J., van Rooijen N., Scheffer G.L., et al. Hepatic Mrp4 induction following acetaminophen exposure is dependent on Kupffer cell function. Am J Physiol-Gastrointest Liver Physiol 2008, 295(2):294-304.
-
(2008)
Am J Physiol-Gastrointest Liver Physiol
, vol.295
, Issue.2
, pp. 294-304
-
-
Campion, S.N.1
Johnson, R.2
Aleksunes, L.M.3
Goedken, M.J.4
van Rooijen, N.5
Scheffer, G.L.6
-
19
-
-
0023037216
-
Potential role of activated macrophages in acetaminophen hepatotoxicity. I. Isolation and characterization of activated macrophages from rat liver
-
Laskin D., Pilaro A.M. Potential role of activated macrophages in acetaminophen hepatotoxicity. I. Isolation and characterization of activated macrophages from rat liver. Toxicol Appl Pharmacol 1986, 86(2):204-215.
-
(1986)
Toxicol Appl Pharmacol
, vol.86
, Issue.2
, pp. 204-215
-
-
Laskin, D.1
Pilaro, A.M.2
-
20
-
-
0022968021
-
Potential role of activated macrophages in acetaminophen hepatotoxicity. II. Mechanism of macrophage accumulation and activation
-
Laskin D.L., Pilaro A.M., Ji S. Potential role of activated macrophages in acetaminophen hepatotoxicity. II. Mechanism of macrophage accumulation and activation. Toxicol Appl Pharmacol 1986, 86(2):216-226.
-
(1986)
Toxicol Appl Pharmacol
, vol.86
, Issue.2
, pp. 216-226
-
-
Laskin, D.L.1
Pilaro, A.M.2
Ji, S.3
-
21
-
-
0035007341
-
Protective effect of rhlL-11 in murine model of acetaminophen-induced hepatotoxicity
-
Trepicchio W.L., Bozza M., Bouchard P., Dorner A.J. Protective effect of rhlL-11 in murine model of acetaminophen-induced hepatotoxicity. Toxicol Pathol 2001, 29(2):242-249.
-
(2001)
Toxicol Pathol
, vol.29
, Issue.2
, pp. 242-249
-
-
Trepicchio, W.L.1
Bozza, M.2
Bouchard, P.3
Dorner, A.J.4
-
22
-
-
0028948724
-
Modulation of macrophage functioning abrogates the acute hepatotoxicity of acetaminophen
-
Laskin D.L., Gardner C.R., Price V.F., Jollow D.J. Modulation of macrophage functioning abrogates the acute hepatotoxicity of acetaminophen. J Hepatol 1995, 21(4):1045-1050.
-
(1995)
J Hepatol
, vol.21
, Issue.4
, pp. 1045-1050
-
-
Laskin, D.L.1
Gardner, C.R.2
Price, V.F.3
Jollow, D.J.4
-
23
-
-
0033000310
-
Pretreatment of mice with macrophage inactivators decreases acetaminophen hepatotoxicity and the formation of reactive oxygen and nitrogen species
-
Michael S.L., Pumford N.R., Mayeux P.R., Niesman M.R., Hinson J.A. Pretreatment of mice with macrophage inactivators decreases acetaminophen hepatotoxicity and the formation of reactive oxygen and nitrogen species. J Hepatol 1999, 30(1):186-195.
-
(1999)
J Hepatol
, vol.30
, Issue.1
, pp. 186-195
-
-
Michael, S.L.1
Pumford, N.R.2
Mayeux, P.R.3
Niesman, M.R.4
Hinson, J.A.5
-
24
-
-
0029844037
-
Role of macrophages in acetaminophen (paracetamol)-induced hepatotoxicity
-
Goldin R.D., Ratnayaka I.D., Breach C.S., Brown I.N., Wickramasinghe S.N. Role of macrophages in acetaminophen (paracetamol)-induced hepatotoxicity. J Pathol 1996, 179(4):432-435.
-
(1996)
J Pathol
, vol.179
, Issue.4
, pp. 432-435
-
-
Goldin, R.D.1
Ratnayaka, I.D.2
Breach, C.S.3
Brown, I.N.4
Wickramasinghe, S.N.5
-
25
-
-
0036913249
-
Protective role of Kupffer cells in acetaminophen-induced hepatic injury in mice
-
Ju C., Reilly T.P., Bourdi M., Radonovich M.F., Brady J.N., George J.W., et al. Protective role of Kupffer cells in acetaminophen-induced hepatic injury in mice. Chem Res Toxicol 2002, 15(12):1504-1513.
-
(2002)
Chem Res Toxicol
, vol.15
, Issue.12
, pp. 1504-1513
-
-
Ju, C.1
Reilly, T.P.2
Bourdi, M.3
Radonovich, M.F.4
Brady, J.N.5
George, J.W.6
-
26
-
-
77950485581
-
Exacerbation of acetaminophen-induced disturbances of liver sinusoidal endothelial cells in the absence of Kupffer cells in mice
-
Holt M.P., Yin H., Ju C. Exacerbation of acetaminophen-induced disturbances of liver sinusoidal endothelial cells in the absence of Kupffer cells in mice. Toxicol Lett 2010, 194(1-2):34-41.
-
(2010)
Toxicol Lett
, vol.194
, Issue.1-2
, pp. 34-41
-
-
Holt, M.P.1
Yin, H.2
Ju, C.3
-
27
-
-
0346727504
-
Role of nitric oxide in hepatic microvascular injury elicited by acetaminophen in mice
-
Ito Y., Abril E.R., Bethea N.W., McCuskey R.S. Role of nitric oxide in hepatic microvascular injury elicited by acetaminophen in mice. Am J Physiol-Gastrointest Liver Physiol 2004, 286(1):60-67.
-
(2004)
Am J Physiol-Gastrointest Liver Physiol
, vol.286
, Issue.1
, pp. 60-67
-
-
Ito, Y.1
Abril, E.R.2
Bethea, N.W.3
McCuskey, R.S.4
-
28
-
-
57149108312
-
Identification and characterization of infiltrating macrophages in acetaminophen-induced liver injury
-
Holt M.P., Cheng L., Ju C. Identification and characterization of infiltrating macrophages in acetaminophen-induced liver injury. J Leukoc Biol 2008, 84(6):1410-1421.
-
(2008)
J Leukoc Biol
, vol.84
, Issue.6
, pp. 1410-1421
-
-
Holt, M.P.1
Cheng, L.2
Ju, C.3
-
29
-
-
0036242256
-
Role of CCR2 in macrophage migration into the liver during acetaminophen-induced hepatotoxicity in the mouse
-
Dambach D.M., Watson L.M., Gray K.R., Durham S.K., Laskin D.L. Role of CCR2 in macrophage migration into the liver during acetaminophen-induced hepatotoxicity in the mouse. J Hepatol 2002, 35(5):1093-1103.
-
(2002)
J Hepatol
, vol.35
, Issue.5
, pp. 1093-1103
-
-
Dambach, D.M.1
Watson, L.M.2
Gray, K.R.3
Durham, S.K.4
Laskin, D.L.5
-
30
-
-
0032867463
-
Novel CXCR2-dependent liver regenerative qualities of ELR-containing CXC chemokines
-
Hogaboam C.M., Bone-Larson C.L., Steinhauser M.L., Lukacs N.W., Colletti L.M., Simpson K.J., et al. Novel CXCR2-dependent liver regenerative qualities of ELR-containing CXC chemokines. J Fed Am Societies Exp Biol 1999, 13(12):1565-1574.
-
(1999)
J Fed Am Societies Exp Biol
, vol.13
, Issue.12
, pp. 1565-1574
-
-
Hogaboam, C.M.1
Bone-Larson, C.L.2
Steinhauser, M.L.3
Lukacs, N.W.4
Colletti, L.M.5
Simpson, K.J.6
-
31
-
-
0038241619
-
Mechanisms for sensitization to TNF-induced apoptosis by acute glutathione depletion in murine hapatocytes
-
Matsumaru K., Ji C., Kaplowitz N. Mechanisms for sensitization to TNF-induced apoptosis by acute glutathione depletion in murine hapatocytes. J Hepatol 2003, 37(6):1425-1434.
-
(2003)
J Hepatol
, vol.37
, Issue.6
, pp. 1425-1434
-
-
Matsumaru, K.1
Ji, C.2
Kaplowitz, N.3
-
32
-
-
32544432347
-
Distinct roles of NF-kappaB p50 in the regulation of acetaminophen-induced inflammatory mediator production and hepatotoxicity
-
Dambach D.M., Durham S.K., Laskin J.D., Laskin D.L. Distinct roles of NF-kappaB p50 in the regulation of acetaminophen-induced inflammatory mediator production and hepatotoxicity. Toxicol Appl Pharmacol 2006, 211(2):157-165.
-
(2006)
Toxicol Appl Pharmacol
, vol.211
, Issue.2
, pp. 157-165
-
-
Dambach, D.M.1
Durham, S.K.2
Laskin, J.D.3
Laskin, D.L.4
-
33
-
-
0029058466
-
Role of proinflammatory cytokines in acetaminophen hepatotoxicity
-
Blazka M.E., Wilmer J.L., Holladay S.D., Wilson R.E., Luster M.I Role of proinflammatory cytokines in acetaminophen hepatotoxicity. Toxicol Appl Pharmacol 1995, 133(1):43-52.
-
(1995)
Toxicol Appl Pharmacol
, vol.133
, Issue.1
, pp. 43-52
-
-
Blazka, M.E.1
Wilmer, J.L.2
Holladay, S.D.3
Wilson, R.E.4
Luster, M.I.5
-
34
-
-
0029871839
-
Histopathology of acetaminophen-induced liver changes: role of interleukin 1 alpha and tumor necrosis factor alpha
-
Blazka M.E., Elwell M.R., Holladay S.D., Wilson R.E., Luster M.I. Histopathology of acetaminophen-induced liver changes: role of interleukin 1 alpha and tumor necrosis factor alpha. Toxicol Pathol 1996, 24(2):181-189.
-
(1996)
Toxicol Pathol
, vol.24
, Issue.2
, pp. 181-189
-
-
Blazka, M.E.1
Elwell, M.R.2
Holladay, S.D.3
Wilson, R.E.4
Luster, M.I.5
-
35
-
-
0842282902
-
The pathogenic roles of tumor necrosis factor receptor p55 in acetaminophen-induced liver injury in mice
-
Ishida Y., Kondo T., Tsuneyama K., Lu P., Takayasu T., Mukaida N. The pathogenic roles of tumor necrosis factor receptor p55 in acetaminophen-induced liver injury in mice. J Leukoc Biol 2004, 75(1):59-67.
-
(2004)
J Leukoc Biol
, vol.75
, Issue.1
, pp. 59-67
-
-
Ishida, Y.1
Kondo, T.2
Tsuneyama, K.3
Lu, P.4
Takayasu, T.5
Mukaida, N.6
-
36
-
-
0034061236
-
Inhibition of tumor necrosis factor alpha does not prevent experimental paracetamol-induced hepatic necrosis
-
Simpson K.J., Lukacs N.W., McGregor A.H., Harrsion D.J., Streiter R.M., Kunkel S.L. Inhibition of tumor necrosis factor alpha does not prevent experimental paracetamol-induced hepatic necrosis. J Pathol 2000, 190(4):489-494.
-
(2000)
J Pathol
, vol.190
, Issue.4
, pp. 489-494
-
-
Simpson, K.J.1
Lukacs, N.W.2
McGregor, A.H.3
Harrsion, D.J.4
Streiter, R.M.5
Kunkel, S.L.6
-
37
-
-
0031924162
-
Acetaminophen hepatotoxicity in tumor necrosis factor/lymphotoxin-alpha gene knockout mice
-
Boess F., Bopst M., Althaus R., Polsky S., Cohen S.D., Eugster H.P., et al. Acetaminophen hepatotoxicity in tumor necrosis factor/lymphotoxin-alpha gene knockout mice. J Hepatol 1998, 27(4):1021-1029.
-
(1998)
J Hepatol
, vol.27
, Issue.4
, pp. 1021-1029
-
-
Boess, F.1
Bopst, M.2
Althaus, R.3
Polsky, S.4
Cohen, S.D.5
Eugster, H.P.6
-
38
-
-
0141503509
-
Exaggerated hepatotoxicity of acetaminophen in mice lacking tumor necrosis factor receptor-1. Potential role of inflammatory mediators
-
Gardner C.R., Laskin J.D., Dambach D.M., Chiu H., Durham S.K., Zhou P., et al. Exaggerated hepatotoxicity of acetaminophen in mice lacking tumor necrosis factor receptor-1. Potential role of inflammatory mediators. Toxicol Appl Pharmacol 2003, 192(2):119-130.
-
(2003)
Toxicol Appl Pharmacol
, vol.192
, Issue.2
, pp. 119-130
-
-
Gardner, C.R.1
Laskin, J.D.2
Dambach, D.M.3
Chiu, H.4
Durham, S.K.5
Zhou, P.6
-
39
-
-
21244451115
-
Tumor necrosis factor receptor 1 and hepatocyte regeneration in acetaminophen toxicity: a kinetic study of proliferating cell nuclear antigen and cytokine expression
-
James L.P., Kurten R.C., Lamps L.W., McCullough S., Hinson J.A. Tumor necrosis factor receptor 1 and hepatocyte regeneration in acetaminophen toxicity: a kinetic study of proliferating cell nuclear antigen and cytokine expression. Basic Clin Pharmacol Toxicol 2005, 97(1):8-14.
-
(2005)
Basic Clin Pharmacol Toxicol
, vol.97
, Issue.1
, pp. 8-14
-
-
James, L.P.1
Kurten, R.C.2
Lamps, L.W.3
McCullough, S.4
Hinson, J.A.5
-
40
-
-
0142244128
-
Role of p55 tumor necrosis factor receptor 1 in acetaminophen-induced antioxidant defense
-
Chiu H., Gardener C.R., Dambach D.M., Brittingham J.A., Durham S.K., Laskin J.D., et al. Role of p55 tumor necrosis factor receptor 1 in acetaminophen-induced antioxidant defense. Am J Physiol-Gastrointest Liver Physiol 2003, 285(5):959-966.
-
(2003)
Am J Physiol-Gastrointest Liver Physiol
, vol.285
, Issue.5
, pp. 959-966
-
-
Chiu, H.1
Gardener, C.R.2
Dambach, D.M.3
Brittingham, J.A.4
Durham, S.K.5
Laskin, J.D.6
-
41
-
-
0345687490
-
Role of tumor necrosis factor receptor 1 (p55) in hepatocyte proliferation during acetaminophen induced toxicity in mice
-
Chiu H., Gardner C.R., Dambach D.M., Durham S.K., Brittingham J.A., Laskin J.D., et al. Role of tumor necrosis factor receptor 1 (p55) in hepatocyte proliferation during acetaminophen induced toxicity in mice. Toxicol Appl Pharmacol 2003, 193(2):218-227.
-
(2003)
Toxicol Appl Pharmacol
, vol.193
, Issue.2
, pp. 218-227
-
-
Chiu, H.1
Gardner, C.R.2
Dambach, D.M.3
Durham, S.K.4
Brittingham, J.A.5
Laskin, J.D.6
-
42
-
-
70349655657
-
Protective effects from carnosine and histidine on acetaminophen-induced liver injury
-
Yan S.L., Wu S.T., Yin M.C., Chen H.T., Chen H.C. Protective effects from carnosine and histidine on acetaminophen-induced liver injury. J Food Sci 2009, 74(8):259-265.
-
(2009)
J Food Sci
, vol.74
, Issue.8
, pp. 259-265
-
-
Yan, S.L.1
Wu, S.T.2
Yin, M.C.3
Chen, H.T.4
Chen, H.C.5
-
43
-
-
73749085094
-
Hepatoprotective effects of an active part from Artemisia sacrorum Ledeb. against acetaminophen-induced toxicity in mice
-
Yuan H.D., Jin G.Z., Piao G.C. Hepatoprotective effects of an active part from Artemisia sacrorum Ledeb. against acetaminophen-induced toxicity in mice. J Ethnopharmacol 2010, 127(2):528-533.
-
(2010)
J Ethnopharmacol
, vol.127
, Issue.2
, pp. 528-533
-
-
Yuan, H.D.1
Jin, G.Z.2
Piao, G.C.3
-
44
-
-
84940561205
-
Hepatoprotective and antioxidant effects of gallic acid in paracetamol-induced liver damage in mice
-
Rasool M.K., Sabina E.P., Ramya S.R., Preety P., Patel S., Mandal N., et al. Hepatoprotective and antioxidant effects of gallic acid in paracetamol-induced liver damage in mice. J Pharm Pharmacol 2010, 62(5):638-643.
-
(2010)
J Pharm Pharmacol
, vol.62
, Issue.5
, pp. 638-643
-
-
Rasool, M.K.1
Sabina, E.P.2
Ramya, S.R.3
Preety, P.4
Patel, S.5
Mandal, N.6
-
45
-
-
33947159213
-
Role of IL-6 in an IL-10 and IL-4 double knockout mouse model uniquely susceptible to acetaminophen-induced liver injury
-
Bourdi M., Eiras D.P., Holt M.P., Webster M.R., Reilly T.P., Wlech K.D., et al. Role of IL-6 in an IL-10 and IL-4 double knockout mouse model uniquely susceptible to acetaminophen-induced liver injury. Chem Res Toxicol 2007, 20(2):208-216.
-
(2007)
Chem Res Toxicol
, vol.20
, Issue.2
, pp. 208-216
-
-
Bourdi, M.1
Eiras, D.P.2
Holt, M.P.3
Webster, M.R.4
Reilly, T.P.5
Wlech, K.D.6
-
46
-
-
34250733492
-
Hepatoprotective role of endogenous interleukin-13 in a murine model of acetaminophen-induced liver disease
-
Yee S.B., Bourdi M., Masson M.J., Pohl L.R. Hepatoprotective role of endogenous interleukin-13 in a murine model of acetaminophen-induced liver disease. Chem Res Toxicol 2007, 20(5):734-744.
-
(2007)
Chem Res Toxicol
, vol.20
, Issue.5
, pp. 734-744
-
-
Yee, S.B.1
Bourdi, M.2
Masson, M.J.3
Pohl, L.R.4
-
47
-
-
9644289366
-
Innate immune system plays a critical role in determining the progression and severity of acetaminophen hepatotoxicity
-
Liu Z.X., Govindarajan S., Kaplowitz N. Innate immune system plays a critical role in determining the progression and severity of acetaminophen hepatotoxicity. Gastroenterology 2004, 127(6):1760-1774.
-
(2004)
Gastroenterology
, vol.127
, Issue.6
, pp. 1760-1774
-
-
Liu, Z.X.1
Govindarajan, S.2
Kaplowitz, N.3
-
48
-
-
0033891369
-
Reduction of liver Fas expression by an antisense oligonucleotide protects mice from fulminant hepatitis
-
Zhang H., Cook J., Nickel J., Yu R., Stecker K., Myers K., et al. Reduction of liver Fas expression by an antisense oligonucleotide protects mice from fulminant hepatitis. Nat Biotechnol 2000, 18:862-867.
-
(2000)
Nat Biotechnol
, vol.18
, pp. 862-867
-
-
Zhang, H.1
Cook, J.2
Nickel, J.3
Yu, R.4
Stecker, K.5
Myers, K.6
-
49
-
-
51349122739
-
Pathogenic role of natural killer T and natural killer cells in acetaminophen-induced liver injury in mice is dependent on the presence of dimethyl sulfoxide
-
Masson M.J., Carpenter L.D., Graf M.L., Pohl L.R. Pathogenic role of natural killer T and natural killer cells in acetaminophen-induced liver injury in mice is dependent on the presence of dimethyl sulfoxide. J Hepatol 2008, 48(3):889-897.
-
(2008)
J Hepatol
, vol.48
, Issue.3
, pp. 889-897
-
-
Masson, M.J.1
Carpenter, L.D.2
Graf, M.L.3
Pohl, L.R.4
-
50
-
-
0036325858
-
A pivotal involvement of IFN-gamma in the pathogenesis of acetaminophen-induced acute liver injury
-
Ishida Y., Kondo T., Ohshima T., Fujiwara H., Iwakura Y., Mukaida N. A pivotal involvement of IFN-gamma in the pathogenesis of acetaminophen-induced acute liver injury. J Fed Am Societies Exp Biol 2002, 16(10):1227-1236.
-
(2002)
J Fed Am Societies Exp Biol
, vol.16
, Issue.10
, pp. 1227-1236
-
-
Ishida, Y.1
Kondo, T.2
Ohshima, T.3
Fujiwara, H.4
Iwakura, Y.5
Mukaida, N.6
-
51
-
-
0033848060
-
Exaggerated hepatic injury due to acetaminophen challenge in mice lacking C-C chemokine receptor 2
-
Hogaboam C.M., Bone-Larson C.L., Steinhauser M.L., Matsukawa A., Gosling J., Boring L., et al. Exaggerated hepatic injury due to acetaminophen challenge in mice lacking C-C chemokine receptor 2. Am J Pathol 2000, 156(4):1245-1252.
-
(2000)
Am J Pathol
, vol.156
, Issue.4
, pp. 1245-1252
-
-
Hogaboam, C.M.1
Bone-Larson, C.L.2
Steinhauser, M.L.3
Matsukawa, A.4
Gosling, J.5
Boring, L.6
-
52
-
-
33947245418
-
Over expression of suppressor of cytokine signaling-3 in T cells exacerbates acetaminophen-induced hepatotoxicity
-
Numata K., Kubo M., Watanabe H., Takagi K., Mizuta H., Okada S., et al. Over expression of suppressor of cytokine signaling-3 in T cells exacerbates acetaminophen-induced hepatotoxicity. J Immunol 2007, 178(6):3777-3785.
-
(2007)
J Immunol
, vol.178
, Issue.6
, pp. 3777-3785
-
-
Numata, K.1
Kubo, M.2
Watanabe, H.3
Takagi, K.4
Mizuta, H.5
Okada, S.6
-
53
-
-
0029121479
-
Chemotactic factors released from hepatocytes exposed to acetaminophen
-
Takada H., Mawet E., Shiratori Y., Hikiba Y., Nakata R., Yoshida H., et al. Chemotactic factors released from hepatocytes exposed to acetaminophen. Dig Dis Sci J 1995, 40(8):1831-1836.
-
(1995)
Dig Dis Sci J
, vol.40
, Issue.8
, pp. 1831-1836
-
-
Takada, H.1
Mawet, E.2
Shiratori, Y.3
Hikiba, Y.4
Nakata, R.5
Yoshida, H.6
-
54
-
-
0030943046
-
Influence of acetaminophen treatment and hydrogen peroxide treatment on the release of a CINC-related protein and TNF-alpha from rat hepatocyte cultures
-
Horbach M., Gerber E., Kahl R. Influence of acetaminophen treatment and hydrogen peroxide treatment on the release of a CINC-related protein and TNF-alpha from rat hepatocyte cultures. J Toxicol 1997, 121(2):117-126.
-
(1997)
J Toxicol
, vol.121
, Issue.2
, pp. 117-126
-
-
Horbach, M.1
Gerber, E.2
Kahl, R.3
-
55
-
-
0034127036
-
The hepatic inflammatory response after acetaminophen overdose: role of neutrophils
-
Lawson J.A., Farhood A., Hopper R.D., Bajt M.L., Jaeschke H. The hepatic inflammatory response after acetaminophen overdose: role of neutrophils. Toxicol Sci 2000, 54(2):509-516.
-
(2000)
Toxicol Sci
, vol.54
, Issue.2
, pp. 509-516
-
-
Lawson, J.A.1
Farhood, A.2
Hopper, R.D.3
Bajt, M.L.4
Jaeschke, H.5
-
56
-
-
33645950774
-
Opposite roles of neutrophils and macrophages in the pathogenesis of acetaminophen-induced acute liver injury
-
Ishida Y., Kondo T., Kimura A., Tsuneyama K., Takayasu T., Mukaida N. Opposite roles of neutrophils and macrophages in the pathogenesis of acetaminophen-induced acute liver injury. Eur J Immunol 2006, 36(4):1028-1038.
-
(2006)
Eur J Immunol
, vol.36
, Issue.4
, pp. 1028-1038
-
-
Ishida, Y.1
Kondo, T.2
Kimura, A.3
Tsuneyama, K.4
Takayasu, T.5
Mukaida, N.6
-
57
-
-
0032430858
-
Role of neutrophils in hepatotoxicity induced by oral acetaminophen administration in rats
-
Smith G.S., Nadig D.E., Kokoska E.R., Solomon H., Tiniakos D.G, Miller T.A. Role of neutrophils in hepatotoxicity induced by oral acetaminophen administration in rats. J Surg Res 1998, 80(2):252-258.
-
(1998)
J Surg Res
, vol.80
, Issue.2
, pp. 252-258
-
-
Smith, G.S.1
Nadig, D.E.2
Kokoska, E.R.3
Solomon, H.4
Tiniakos, D.G.5
Miller, T.A.6
-
58
-
-
33745549377
-
Neutrophil depletion protects against murine acetaminophen hepatotoxicity
-
Liu Z.X., Han D., Gunawan B., Kaplowitz N. Neutrophil depletion protects against murine acetaminophen hepatotoxicity. J Hepatol 2006, 43(6):1220-1230.
-
(2006)
J Hepatol
, vol.43
, Issue.6
, pp. 1220-1230
-
-
Liu, Z.X.1
Han, D.2
Gunawan, B.3
Kaplowitz, N.4
-
59
-
-
33745522546
-
Pathophysiological role of the acute inflammatory response during acetaminophen hepatotoxicity
-
Cover C., Liu J., Farhood A., Malle E., Waalkes M.P., Bajt M.L., et al. Pathophysiological role of the acute inflammatory response during acetaminophen hepatotoxicity. Toxicol Appl Pharmacol 2006, 216(1):98-107.
-
(2006)
Toxicol Appl Pharmacol
, vol.216
, Issue.1
, pp. 98-107
-
-
Cover, C.1
Liu, J.2
Farhood, A.3
Malle, E.4
Waalkes, M.P.5
Bajt, M.L.6
-
60
-
-
78349236196
-
Acetaminophen-induced hepatic neutrophil accumulation and inflammatory liver injury in CD18-deficient mice
-
Williams C.D., Bajt M.L., Farhood A., Jaeschke H. Acetaminophen-induced hepatic neutrophil accumulation and inflammatory liver injury in CD18-deficient mice. Liver Int 2010, 30(9):1280-1292.
-
(2010)
Liver Int
, vol.30
, Issue.9
, pp. 1280-1292
-
-
Williams, C.D.1
Bajt, M.L.2
Farhood, A.3
Jaeschke, H.4
-
61
-
-
0344117500
-
Acetaminophen toxicity in mice lacking NADPH oxidase activity: role of peroxynitrite formation and mitochondrial oxidant stress
-
James L.P., McCullough S.S., Knight T.R., Jaeschke H., Hinson J.A. Acetaminophen toxicity in mice lacking NADPH oxidase activity: role of peroxynitrite formation and mitochondrial oxidant stress. Free Radic Res 2003, 37:1289-1297.
-
(2003)
Free Radic Res
, vol.37
, pp. 1289-1297
-
-
James, L.P.1
McCullough, S.S.2
Knight, T.R.3
Jaeschke, H.4
Hinson, J.A.5
-
62
-
-
34250310047
-
Neutrophil depletion protects against murine acetaminophen hepatotoxicity: another perspective
-
Jaeschke H., Liu J. Neutrophil depletion protects against murine acetaminophen hepatotoxicity: another perspective. J Hepatol 2007, 45(6):1588-1589.
-
(2007)
J Hepatol
, vol.45
, Issue.6
, pp. 1588-1589
-
-
Jaeschke, H.1
Liu, J.2
-
63
-
-
83255192265
-
Acetaminophen hepatotoxicity and repair: the role of sterile inflammation and innate immunity
-
Jaeschke H., Williams C.D., Ramachandran A., Bajt M.L. Acetaminophen hepatotoxicity and repair: the role of sterile inflammation and innate immunity. Liver Int 2011, 32(1):8-20.
-
(2011)
Liver Int
, vol.32
, Issue.1
, pp. 8-20
-
-
Jaeschke, H.1
Williams, C.D.2
Ramachandran, A.3
Bajt, M.L.4
-
64
-
-
0041407282
-
Hyaluronic acid and endothelial damage due to paracetamol-induced hepatotoxicity
-
Williams A.M., Langley P.G., Osei-Hwediah J., Wendon J.A., Hughes R.D. Hyaluronic acid and endothelial damage due to paracetamol-induced hepatotoxicity. Liver Int 2003, 23(2):110-115.
-
(2003)
Liver Int
, vol.23
, Issue.2
, pp. 110-115
-
-
Williams, A.M.1
Langley, P.G.2
Osei-Hwediah, J.3
Wendon, J.A.4
Hughes, R.D.5
-
65
-
-
0030793294
-
Sinusoidal endothelial cells as a target for acetaminophen toxicity. Direct action versus requirement for hepatocyte activation in different mouse strains
-
DeLeve L.D., Wang X., Kaplowitz N., Shulman H.M., Bart J.A., van der Hoek A. Sinusoidal endothelial cells as a target for acetaminophen toxicity. Direct action versus requirement for hepatocyte activation in different mouse strains. Biochem Pharmacol 1997, 53(9):1339-1345.
-
(1997)
Biochem Pharmacol
, vol.53
, Issue.9
, pp. 1339-1345
-
-
DeLeve, L.D.1
Wang, X.2
Kaplowitz, N.3
Shulman, H.M.4
Bart, J.A.5
van der Hoek, A.6
-
66
-
-
0347080722
-
Early hepatic microvascular injury in response to acetaminophen toxicity
-
Ito Y., Bethna N.W., Abril E.R., McCuskey R.S. Early hepatic microvascular injury in response to acetaminophen toxicity. Microcirculation 2003, 10(5):391-400.
-
(2003)
Microcirculation
, vol.10
, Issue.5
, pp. 391-400
-
-
Ito, Y.1
Bethna, N.W.2
Abril, E.R.3
McCuskey, R.S.4
-
67
-
-
33646513512
-
Endothelially derived nitric oxide affects the severity of early acetaminophen-induced hepatic injury in mice
-
Salhanick S.D., Orlow D., Holt D.E., Pavlides S., Reenstra W., Buras J.A. Endothelially derived nitric oxide affects the severity of early acetaminophen-induced hepatic injury in mice. Acad Emerg Med 2006, 13(5):479-485.
-
(2006)
Acad Emerg Med
, vol.13
, Issue.5
, pp. 479-485
-
-
Salhanick, S.D.1
Orlow, D.2
Holt, D.E.3
Pavlides, S.4
Reenstra, W.5
Buras, J.A.6
-
68
-
-
77449150253
-
The role of prostacyclin in modifying acute hepatotoxicity of acetaminophen in mice
-
Cavar I., Kelava T., Heinzel R., Culo F. The role of prostacyclin in modifying acute hepatotoxicity of acetaminophen in mice. Coll Anthropol 2009, 33(2):25-29.
-
(2009)
Coll Anthropol
, vol.33
, Issue.2
, pp. 25-29
-
-
Cavar, I.1
Kelava, T.2
Heinzel, R.3
Culo, F.4
-
69
-
-
79952080602
-
Vascular growth factor receptor-1 signaling promotes liver repair through restoration of liver microvasculature after acetaminophen hepatotoxicity
-
Kato T., Ito Y., Hosono K., Suzuki T., Tamaki H., Minamino T., et al. Vascular growth factor receptor-1 signaling promotes liver repair through restoration of liver microvasculature after acetaminophen hepatotoxicity. Toxicol Sci 2011, 120(1):218-229.
-
(2011)
Toxicol Sci
, vol.120
, Issue.1
, pp. 218-229
-
-
Kato, T.1
Ito, Y.2
Hosono, K.3
Suzuki, T.4
Tamaki, H.5
Minamino, T.6
-
70
-
-
79954631441
-
Acetaminophen hepatotoxicity and HIF-1α induction in acetaminophen toxicity in mice occurs without hypoxia
-
Chaudhuri S., McCullough S.S., Hennings L., Letzig L., Simpson P.M., Hinson J.A., et al. Acetaminophen hepatotoxicity and HIF-1α induction in acetaminophen toxicity in mice occurs without hypoxia. Toxicol Appl Pharmacol 2011, 252(3):211-220.
-
(2011)
Toxicol Appl Pharmacol
, vol.252
, Issue.3
, pp. 211-220
-
-
Chaudhuri, S.1
McCullough, S.S.2
Hennings, L.3
Letzig, L.4
Simpson, P.M.5
Hinson, J.A.6
-
71
-
-
79960481622
-
The role of hypoxia-inducible factor-1α in acetaminophen hepatotoxicity
-
Sparkenbaugh E.M., Saini Y., Greenwood K.K, LaPres J.J., Luyendyk J.P., Copple B.L., et al. The role of hypoxia-inducible factor-1α in acetaminophen hepatotoxicity. J Pharmacol Exp Ther 2011, 338(2):492-502.
-
(2011)
J Pharmacol Exp Ther
, vol.338
, Issue.2
, pp. 492-502
-
-
Sparkenbaugh, E.M.1
Saini, Y.2
Greenwood, K.K.3
LaPres, J.J.4
Luyendyk, J.P.5
Copple, B.L.6
-
72
-
-
0024781736
-
Effects of inhibitors of phospholipase A2, cyclooxygenase and thromboxane synthetase on paracetamol hepatotoxicity in the rat
-
Horton A.A., Wood J.M. Effects of inhibitors of phospholipase A2, cyclooxygenase and thromboxane synthetase on paracetamol hepatotoxicity in the rat. Eicosanoids 1989, 2(2):123-129.
-
(1989)
Eicosanoids
, vol.2
, Issue.2
, pp. 123-129
-
-
Horton, A.A.1
Wood, J.M.2
-
73
-
-
0025914692
-
Prevention of paracetamol-induced hepatotoxicity in the rat by the thromboxane receptor antagonist, Sulotroban (BM 13177)
-
Horton A.A., Wood J.M. Prevention of paracetamol-induced hepatotoxicity in the rat by the thromboxane receptor antagonist, Sulotroban (BM 13177). J Lipid Mediators Cell Signalling 1991, 4(2):245-247.
-
(1991)
J Lipid Mediators Cell Signalling
, vol.4
, Issue.2
, pp. 245-247
-
-
Horton, A.A.1
Wood, J.M.2
-
74
-
-
0035663287
-
A protective role for cyclooxygenase-2 in drug-induced liver injury in mice
-
Reilly T.P., Brady J.N., Marchick M.R., Bourdi M., George J.W., Randovich M.F., et al. A protective role for cyclooxygenase-2 in drug-induced liver injury in mice. Chem Res Toxicol 2001, 14(12):1620-1628.
-
(2001)
Chem Res Toxicol
, vol.14
, Issue.12
, pp. 1620-1628
-
-
Reilly, T.P.1
Brady, J.N.2
Marchick, M.R.3
Bourdi, M.4
George, J.W.5
Randovich, M.F.6
-
75
-
-
77956633418
-
The role of prostaglandin E2 in acute acetaminophen hepatotoxicity in mice
-
Cavar I., Kelava T., Vukojević K., Saraga-Babić M., Culo F. The role of prostaglandin E2 in acute acetaminophen hepatotoxicity in mice. Histol Histopathol 2010, 25(7):819-830.
-
(2010)
Histol Histopathol
, vol.25
, Issue.7
, pp. 819-830
-
-
Cavar, I.1
Kelava, T.2
Vukojević, K.3
Saraga-Babić, M.4
Culo, F.5
-
76
-
-
2442507155
-
Morphology of hepatic stellate cells in patients with fulminant or subfulminant hepatitis requiring liver transplantation
-
Bernard P.H., Le Bail B., Carles J., Fawaz R., Balabaud C., Rosenbaum J., et al. Morphology of hepatic stellate cells in patients with fulminant or subfulminant hepatitis requiring liver transplantation. J Submicrosc Cytol Pathol 1996, 28(1):5-12.
-
(1996)
J Submicrosc Cytol Pathol
, vol.28
, Issue.1
, pp. 5-12
-
-
Bernard, P.H.1
Le Bail, B.2
Carles, J.3
Fawaz, R.4
Balabaud, C.5
Rosenbaum, J.6
-
77
-
-
79961013798
-
Depletion of activated hepatic stellate cells correlates with severe liver damage and abnormal liver regeneration in acetaminophen-induced liver injury
-
Shen K., Chang W., Gao X., Wang H., Niu W., Song L., et al. Depletion of activated hepatic stellate cells correlates with severe liver damage and abnormal liver regeneration in acetaminophen-induced liver injury. Acta Biochim Biophys Sin (Shanghai) 2011, 43(4):307-315.
-
(2011)
Acta Biochim Biophys Sin (Shanghai)
, vol.43
, Issue.4
, pp. 307-315
-
-
Shen, K.1
Chang, W.2
Gao, X.3
Wang, H.4
Niu, W.5
Song, L.6
-
78
-
-
80052037842
-
Dendritic cell depletion exacerbates acetaminophen hepatotoxicity
-
Connolly M.K., Ayo D., Malhorta A., Hackman M., Bedrosian A.S., Ibrahim J., et al. Dendritic cell depletion exacerbates acetaminophen hepatotoxicity. J Hepatol 2011, 54(3):959-968.
-
(2011)
J Hepatol
, vol.54
, Issue.3
, pp. 959-968
-
-
Connolly, M.K.1
Ayo, D.2
Malhorta, A.3
Hackman, M.4
Bedrosian, A.S.5
Ibrahim, J.6
-
79
-
-
0036088394
-
Predictors of outcome after acetaminophen poisoning in children and adolescents
-
James L.P., Wells E., Beard R.H., Farrar H.C. Predictors of outcome after acetaminophen poisoning in children and adolescents. J Pediatr 2002, 140(5):522-526.
-
(2002)
J Pediatr
, vol.140
, Issue.5
, pp. 522-526
-
-
James, L.P.1
Wells, E.2
Beard, R.H.3
Farrar, H.C.4
-
80
-
-
25444529963
-
Cytokines and toxicity in acetaminophen overdose
-
James L.P., Simpson P.M., Farrar H.C., Kearns G.L., Wasserman G.S., Blumer J.L., et al. Cytokines and toxicity in acetaminophen overdose. J Clin Pharmacol 2005, 45(10):1165-1171.
-
(2005)
J Clin Pharmacol
, vol.45
, Issue.10
, pp. 1165-1171
-
-
James, L.P.1
Simpson, P.M.2
Farrar, H.C.3
Kearns, G.L.4
Wasserman, G.S.5
Blumer, J.L.6
-
81
-
-
0347407814
-
Prothrombin time prolongation in paracetamol poisoning: a relevant marker of hepatic failure?
-
Payen C., Dachraoui A., Pulce C., Descotes J. Prothrombin time prolongation in paracetamol poisoning: a relevant marker of hepatic failure?. Hum Exp Toxicol 2003, 22(11):617-621.
-
(2003)
Hum Exp Toxicol
, vol.22
, Issue.11
, pp. 617-621
-
-
Payen, C.1
Dachraoui, A.2
Pulce, C.3
Descotes, J.4
-
82
-
-
0041624337
-
New insights into haemostasis in liver failure
-
Kerr R. New insights into haemostasis in liver failure. Blood Coagul Fibrinolysis 2003, 14(1):43-45.
-
(2003)
Blood Coagul Fibrinolysis
, vol.14
, Issue.1
, pp. 43-45
-
-
Kerr, R.1
-
83
-
-
36349032390
-
Role of the coagulation system in acetaminophen-induced hepatotoxicity in mice
-
Ganey P.E., Luyendyk J.P., Newport S.W., Eagle T.M., Maddox J.F., Mackman N., et al. Role of the coagulation system in acetaminophen-induced hepatotoxicity in mice. J Hepatol 2007, 46(4):1177-1186.
-
(2007)
J Hepatol
, vol.46
, Issue.4
, pp. 1177-1186
-
-
Ganey, P.E.1
Luyendyk, J.P.2
Newport, S.W.3
Eagle, T.M.4
Maddox, J.F.5
Mackman, N.6
-
84
-
-
66949144423
-
The regulation of liver cell survival by complement
-
Markiewski M.M., DeAngelis R.A., Strey C.W., Foukas P.G., Gerard C., Gerard N., et al. The regulation of liver cell survival by complement. J Immunol 2009, 182(9):5412-5418.
-
(2009)
J Immunol
, vol.182
, Issue.9
, pp. 5412-5418
-
-
Markiewski, M.M.1
DeAngelis, R.A.2
Strey, C.W.3
Foukas, P.G.4
Gerard, C.5
Gerard, N.6
-
85
-
-
0035849176
-
Complement. Second of two parts
-
Walport M.J. Complement. Second of two parts. N Engl J Med 2001, 344(15):1140-1144.
-
(2001)
N Engl J Med
, vol.344
, Issue.15
, pp. 1140-1144
-
-
Walport, M.J.1
-
86
-
-
1142310879
-
The dark side of C5a in sepsis
-
Ward P.A. The dark side of C5a in sepsis. Nat Rev Immunol 2004, 4(2):133-142.
-
(2004)
Nat Rev Immunol
, vol.4
, Issue.2
, pp. 133-142
-
-
Ward, P.A.1
-
87
-
-
0031048335
-
Neutrophil superoxide and hydrogen peroxide production in patients with acute liver failure
-
Clapperton M., Rolando N., Sandoval L., Davies E., Williams R. Neutrophil superoxide and hydrogen peroxide production in patients with acute liver failure. Eur J Clin Invest 1997, 27(2):164-168.
-
(1997)
Eur J Clin Invest
, vol.27
, Issue.2
, pp. 164-168
-
-
Clapperton, M.1
Rolando, N.2
Sandoval, L.3
Davies, E.4
Williams, R.5
-
88
-
-
0025181831
-
Complement levels in patients with hepatic dysfunction
-
Ellison R.T., Horsburgh C.R., Curd J. Complement levels in patients with hepatic dysfunction. Dig Dis Sci 1990, 35(2):231-235.
-
(1990)
Dig Dis Sci
, vol.35
, Issue.2
, pp. 231-235
-
-
Ellison, R.T.1
Horsburgh, C.R.2
Curd, J.3
-
89
-
-
84859977248
-
The role of complement activation in acetaminophen-induced liver injury in mice
-
Singhal R., Ganey P.E., Roth R.A. The role of complement activation in acetaminophen-induced liver injury in mice. J Pharmacol Exp Ther 2012, 341(2):377-385.
-
(2012)
J Pharmacol Exp Ther
, vol.341
, Issue.2
, pp. 377-385
-
-
Singhal, R.1
Ganey, P.E.2
Roth, R.A.3
-
91
-
-
33845681113
-
Role of neutrophils in a mouse model of halothane-induced liver injury
-
You Q., Cheng L., Reilly T.P., Wegmann D., Ju C. Role of neutrophils in a mouse model of halothane-induced liver injury. J Hepatol 2006, 44(6):1421-1431.
-
(2006)
J Hepatol
, vol.44
, Issue.6
, pp. 1421-1431
-
-
You, Q.1
Cheng, L.2
Reilly, T.P.3
Wegmann, D.4
Ju, C.5
-
92
-
-
77952671411
-
Involvement of natural killer T cells in halothane-induced liver injury in mice
-
Cheng L., You Q., Yin H., Holt M.P., Ju C. Involvement of natural killer T cells in halothane-induced liver injury in mice. Biochem Pharmacol 2010, 80(2):255-261.
-
(2010)
Biochem Pharmacol
, vol.80
, Issue.2
, pp. 255-261
-
-
Cheng, L.1
You, Q.2
Yin, H.3
Holt, M.P.4
Ju, C.5
-
93
-
-
70349298831
-
Halothane-induced liver injury is mediated by interleukin-17 in mice
-
Kobayashi E., Kobayashi M., Tsuneyama K., Fukami T., Nakajima M., Yokoi T. Halothane-induced liver injury is mediated by interleukin-17 in mice. Toxicol Sci 2009, 111(2):302-310.
-
(2009)
Toxicol Sci
, vol.111
, Issue.2
, pp. 302-310
-
-
Kobayashi, E.1
Kobayashi, M.2
Tsuneyama, K.3
Fukami, T.4
Nakajima, M.5
Yokoi, T.6
-
94
-
-
57249103376
-
Interleukin 10 deficiency exacerbate halothane induced liver injury by increasing interleukin 8 expression and neutrophil infiltration
-
Feng D., Wang Y., Xu Y., Luo Q., Lan B., Xu L. Interleukin 10 deficiency exacerbate halothane induced liver injury by increasing interleukin 8 expression and neutrophil infiltration. Biochem Pharmacol 2009, 77(2):277-284.
-
(2009)
Biochem Pharmacol
, vol.77
, Issue.2
, pp. 277-284
-
-
Feng, D.1
Wang, Y.2
Xu, Y.3
Luo, Q.4
Lan, B.5
Xu, L.6
-
95
-
-
77951050219
-
A mouse model of severe halothane hepatitis based on human risk factors
-
Dugan C.M., MacDonald A.E., Roth R.A., Ganey P.E. A mouse model of severe halothane hepatitis based on human risk factors. J Pharmacol Exp Ther 2010, 333(2):364-372.
-
(2010)
J Pharmacol Exp Ther
, vol.333
, Issue.2
, pp. 364-372
-
-
Dugan, C.M.1
MacDonald, A.E.2
Roth, R.A.3
Ganey, P.E.4
-
96
-
-
79953084405
-
Natural killer cells mediate severe liver injury in a murine model of halothane hepatitis
-
Dugan C.M., Fullerton A.M., Roth R.A., Ganey P.E. Natural killer cells mediate severe liver injury in a murine model of halothane hepatitis. Toxicol Sci 2011, 120(2):507-518.
-
(2011)
Toxicol Sci
, vol.120
, Issue.2
, pp. 507-518
-
-
Dugan, C.M.1
Fullerton, A.M.2
Roth, R.A.3
Ganey, P.E.4
-
97
-
-
77954212492
-
Pathological role of stressed-induced glucocorticoids in drug-induced liver injury in mice
-
Masson M.J., Collins L.A., Carpenter L.D., Graf M.L., Ryan P.M., Bourdi M., et al. Pathological role of stressed-induced glucocorticoids in drug-induced liver injury in mice. Biochem Biophys Res Commun 2010, 397(3):453-458.
-
(2010)
Biochem Biophys Res Commun
, vol.397
, Issue.3
, pp. 453-458
-
-
Masson, M.J.1
Collins, L.A.2
Carpenter, L.D.3
Graf, M.L.4
Ryan, P.M.5
Bourdi, M.6
-
98
-
-
79957798819
-
Estradiol and progesterone modulate halothane-induced liver injury in mice
-
Toyoda Y., Miyashita T., Endo S., Tsuneyama K., Fukami T., Nakajima M., et al. Estradiol and progesterone modulate halothane-induced liver injury in mice. Toxicol Lett 2011, 204(1):17-24.
-
(2011)
Toxicol Lett
, vol.204
, Issue.1
, pp. 17-24
-
-
Toyoda, Y.1
Miyashita, T.2
Endo, S.3
Tsuneyama, K.4
Fukami, T.5
Nakajima, M.6
-
99
-
-
17444444908
-
Bacterial endotoxin enhances the hepatotoxicity of allyl alcohol
-
Sneed R.A., Grimes S.D., Schultze A.E., Brown A.P., Ganey P.E. Bacterial endotoxin enhances the hepatotoxicity of allyl alcohol. Toxicol Appl Pharmacol 1997, 144:77-87.
-
(1997)
Toxicol Appl Pharmacol
, vol.144
, pp. 77-87
-
-
Sneed, R.A.1
Grimes, S.D.2
Schultze, A.E.3
Brown, A.P.4
Ganey, P.E.5
-
100
-
-
0034120093
-
Bacterial lipopolysaccharide exposure augments aflatoxin B1-induced liver injury
-
Barton C.C., Hill D.A., Yee S.B., Barton E.X., Ganey P.E., Roth R.A. Bacterial lipopolysaccharide exposure augments aflatoxin B1-induced liver injury. Toxicol Sci 2000, 55:444-452.
-
(2000)
Toxicol Sci
, vol.55
, pp. 444-452
-
-
Barton, C.C.1
Hill, D.A.2
Yee, S.B.3
Barton, E.X.4
Ganey, P.E.5
Roth, R.A.6
-
101
-
-
0033891439
-
Synergistic hepatotoxicity from coexposure to bacterial endotoxin and the pyrrolizidine alkaloid monocrotaline
-
Yee S.B., Kinser S., Hill D.A, Barton C.C., Hotchkiss J.A., Harkema J.R., et al. Synergistic hepatotoxicity from coexposure to bacterial endotoxin and the pyrrolizidine alkaloid monocrotaline. Toxicol Appl Pharmacol 2000, 166:173-1850.
-
(2000)
Toxicol Appl Pharmacol
, vol.166
, pp. 173-1850
-
-
Yee, S.B.1
Kinser, S.2
Hill, D.A.3
Barton, C.C.4
Hotchkiss, J.A.5
Harkema, J.R.6
-
102
-
-
0042824112
-
Viral and clinical factors associated with the fulminant course of hepatitis A infection
-
Rezende G., Roque-Afonso A.M., Samuel D., Gigou M., Nicand E., Ferre V., et al. Viral and clinical factors associated with the fulminant course of hepatitis A infection. J Hepatol 2003, 38(3):613-618.
-
(2003)
J Hepatol
, vol.38
, Issue.3
, pp. 613-618
-
-
Rezende, G.1
Roque-Afonso, A.M.2
Samuel, D.3
Gigou, M.4
Nicand, E.5
Ferre, V.6
-
103
-
-
33745488448
-
Influence of acetaminophen at therapeutic doses on surrogate markers of severity of acute viral hepatitis
-
Yaghi C., Honein K., Boujaoude J., Slim R., Moucari R., Sayegh R. Influence of acetaminophen at therapeutic doses on surrogate markers of severity of acute viral hepatitis. Gastroentérologie Clinique et Biologique 2006, 30(5):763-768.
-
(2006)
Gastroentérologie Clinique et Biologique
, vol.30
, Issue.5
, pp. 763-768
-
-
Yaghi, C.1
Honein, K.2
Boujaoude, J.3
Slim, R.4
Moucari, R.5
Sayegh, R.6
-
104
-
-
71549150588
-
Bacterial- and viral-induced inflammation increases sensitivity to acetaminophen hepatotoxicity
-
Maddox J.F., Amuzie C.J., Li M., Newport S.W., Sparkenbaugh E., Cuff C.F., et al. Bacterial- and viral-induced inflammation increases sensitivity to acetaminophen hepatotoxicity. J Toxicol Environ Health Part A 2010, 73(1):58-73.
-
(2010)
J Toxicol Environ Health Part A
, vol.73
, Issue.1
, pp. 58-73
-
-
Maddox, J.F.1
Amuzie, C.J.2
Li, M.3
Newport, S.W.4
Sparkenbaugh, E.5
Cuff, C.F.6
-
105
-
-
77951663905
-
Role of c-Jun N-terminal kinase (JNK) in regulating tumor necrosis factor-alpha (TNF-alpha) mediated increase of acetaminophen (APAP) and chlorpromazine (CPZ) toxicity in murine hepatocytes
-
Gandhi A., Guo T., Ghose R. Role of c-Jun N-terminal kinase (JNK) in regulating tumor necrosis factor-alpha (TNF-alpha) mediated increase of acetaminophen (APAP) and chlorpromazine (CPZ) toxicity in murine hepatocytes. J Toxicol Sci 2010, 35(2):163-173.
-
(2010)
J Toxicol Sci
, vol.35
, Issue.2
, pp. 163-173
-
-
Gandhi, A.1
Guo, T.2
Ghose, R.3
-
106
-
-
0034608777
-
Endotoxin pretreatment protects against the hepatotoxicity of acetaminophen and carbon tetrachloride: role of cytochrome P450 suppression
-
Liu J., Sendelbach L.E., Parkinson A., Klaassen C.D. Endotoxin pretreatment protects against the hepatotoxicity of acetaminophen and carbon tetrachloride: role of cytochrome P450 suppression. J Toxicol 2000, 147(3):167-176.
-
(2000)
J Toxicol
, vol.147
, Issue.3
, pp. 167-176
-
-
Liu, J.1
Sendelbach, L.E.2
Parkinson, A.3
Klaassen, C.D.4
-
108
-
-
0025037727
-
Histopathology of cocaine hepatotoxicity. Report of four patients
-
Wanless I.R., Dore S., Gopinath N., Tan J., Cameron R., Heathcote E.J., et al. Histopathology of cocaine hepatotoxicity. Report of four patients. Gastroenterology 1990, 98:497-501.
-
(1990)
Gastroenterology
, vol.98
, pp. 497-501
-
-
Wanless, I.R.1
Dore, S.2
Gopinath, N.3
Tan, J.4
Cameron, R.5
Heathcote, E.J.6
-
109
-
-
0025332683
-
Cocaine-induced liver cell injury: comparison of morphological features in man and in experimental models
-
Kanel G.C., Cassidy W., Shuster L., Reynolds T.B. Cocaine-induced liver cell injury: comparison of morphological features in man and in experimental models. J Hepatol 1990, 11:646-651.
-
(1990)
J Hepatol
, vol.11
, pp. 646-651
-
-
Kanel, G.C.1
Cassidy, W.2
Shuster, L.3
Reynolds, T.B.4
-
110
-
-
0043197250
-
Endotoxin potentiates cocaine-mediated hepatotoxicity by nitric oxide and reactive oxygen species
-
Labib R., Turkall R., Abdel-Rahman M.S. Endotoxin potentiates cocaine-mediated hepatotoxicity by nitric oxide and reactive oxygen species. Int J Toxicol 2003, 22:305-316.
-
(2003)
Int J Toxicol
, vol.22
, pp. 305-316
-
-
Labib, R.1
Turkall, R.2
Abdel-Rahman, M.S.3
-
112
-
-
0036154009
-
Underlying endotoxemia augments toxic responses to chlorpromazine: is there a relationship to drug idiosyncrasy?
-
Buchweitz J.P., Ganey P.E., Bursian S.J., Roth R.A. Underlying endotoxemia augments toxic responses to chlorpromazine: is there a relationship to drug idiosyncrasy?. J Pharmacol Exp Ther 2002, 300:460-467.
-
(2002)
J Pharmacol Exp Ther
, vol.300
, pp. 460-467
-
-
Buchweitz, J.P.1
Ganey, P.E.2
Bursian, S.J.3
Roth, R.A.4
-
113
-
-
0141563559
-
Ranitidine treatment during a modest inflammatory response precipitates idiosyncrasy-like liver injury in rats
-
Luyendyk J.P., Maddox J.F., Cosma G.N., Ganey P.E., Cockerell G.L., Roth R.A. Ranitidine treatment during a modest inflammatory response precipitates idiosyncrasy-like liver injury in rats. J Pharmacol Exp Ther 2003, 307:9-16.
-
(2003)
J Pharmacol Exp Ther
, vol.307
, pp. 9-16
-
-
Luyendyk, J.P.1
Maddox, J.F.2
Cosma, G.N.3
Ganey, P.E.4
Cockerell, G.L.5
Roth, R.A.6
-
114
-
-
33644781852
-
Microarray analysis of LPS potentiation of trovafloxacin-induced liver injury in rats suggests a role for proinflammatory chemokines and neutrophils
-
Waring J.F., Liguori M.J., Luyendyk J.P., Maddox J.F., Ganey P.E., Stachlewitz R.F., et al. Microarray analysis of LPS potentiation of trovafloxacin-induced liver injury in rats suggests a role for proinflammatory chemokines and neutrophils. J Pharmacol Exp Ther 2006, 316:1080-1087.
-
(2006)
J Pharmacol Exp Ther
, vol.316
, pp. 1080-1087
-
-
Waring, J.F.1
Liguori, M.J.2
Luyendyk, J.P.3
Maddox, J.F.4
Ganey, P.E.5
Stachlewitz, R.F.6
-
115
-
-
33751183319
-
Modest inflammation enhances diclofenac hepatotoxicity in rats: role of neutrophils and bacterial translocation
-
Deng X., Stachlewitz R.F., Liguori M.J., Blomme E.A., Waring J.F., Luyendyk J.P., et al. Modest inflammation enhances diclofenac hepatotoxicity in rats: role of neutrophils and bacterial translocation. J Pharmacol Exp Ther 2006, 319(3):1191-1199.
-
(2006)
J Pharmacol Exp Ther
, vol.319
, Issue.3
, pp. 1191-1199
-
-
Deng, X.1
Stachlewitz, R.F.2
Liguori, M.J.3
Blomme, E.A.4
Waring, J.F.5
Luyendyk, J.P.6
-
116
-
-
35448973391
-
Lipopolysaccharide and trovafloxacin coexposure in mice causes idiosyncrasy-like liver injury dependent on tumor necrosis factor-alpha
-
Shaw P.J., Hopfensperger M.J., Ganey P.E., Roth R.A. Lipopolysaccharide and trovafloxacin coexposure in mice causes idiosyncrasy-like liver injury dependent on tumor necrosis factor-alpha. Toxicol Sci 2007, 100(1):259-266.
-
(2007)
Toxicol Sci
, vol.100
, Issue.1
, pp. 259-266
-
-
Shaw, P.J.1
Hopfensperger, M.J.2
Ganey, P.E.3
Roth, R.A.4
-
117
-
-
61349127948
-
Hepatotoxic interaction of sulindac with lipopolysaccharide: role of the hemostatic system
-
Zou W., Devi S.S., Sparkenbaugh E., Younis H.S., Roth R.A., Ganey P.E. Hepatotoxic interaction of sulindac with lipopolysaccharide: role of the hemostatic system. Toxicol Sci 2009, 108:184-193.
-
(2009)
Toxicol Sci
, vol.108
, pp. 184-193
-
-
Zou, W.1
Devi, S.S.2
Sparkenbaugh, E.3
Younis, H.S.4
Roth, R.A.5
Ganey, P.E.6
-
118
-
-
84555195380
-
Amiodarone exposure during modest inflammation induces idiosyncrasy-like liver injury in rats: role of tumor necrosis factor-alpha
-
Lu J., Jones A.D., Harkema J.R., Roth R.A., Ganey P.E. Amiodarone exposure during modest inflammation induces idiosyncrasy-like liver injury in rats: role of tumor necrosis factor-alpha. Toxicol Sci 2012, 125(1):126-133.
-
(2012)
Toxicol Sci
, vol.125
, Issue.1
, pp. 126-133
-
-
Lu, J.1
Jones, A.D.2
Harkema, J.R.3
Roth, R.A.4
Ganey, P.E.5
-
119
-
-
80052925417
-
Animal models of idiosyncratic drug-induced liver injury-current status
-
Roth R.A., Ganey P.E. Animal models of idiosyncratic drug-induced liver injury-current status. Crit Rev Toxicol 2011, 41(9):723-739.
-
(2011)
Crit Rev Toxicol
, vol.41
, Issue.9
, pp. 723-739
-
-
Roth, R.A.1
Ganey, P.E.2
-
120
-
-
70349694415
-
Inflammatory stress and idiosyncratic hepatotoxicity: hints from animal models
-
Deng X., Luyendyk J.P., Ganey P.E., Roth R.A. Inflammatory stress and idiosyncratic hepatotoxicity: hints from animal models. Pharmacol Rev 2009, 61:262-282.
-
(2009)
Pharmacol Rev
, vol.61
, pp. 262-282
-
-
Deng, X.1
Luyendyk, J.P.2
Ganey, P.E.3
Roth, R.A.4
-
121
-
-
67649881064
-
Trovafloxacin enhances the inflammatory response to a gram-negative or a gram-positive bacterial stimulus, resulting in neutrophil-dependent liver injury in mice
-
Shaw P., Ganey P.E., Roth R.A. Trovafloxacin enhances the inflammatory response to a gram-negative or a gram-positive bacterial stimulus, resulting in neutrophil-dependent liver injury in mice. J Pharmacol Exp Ther 2009, 330(1):72-78.
-
(2009)
J Pharmacol Exp Ther
, vol.330
, Issue.1
, pp. 72-78
-
-
Shaw, P.1
Ganey, P.E.2
Roth, R.A.3
-
122
-
-
58949083563
-
Effect of polyI:C cotreatment on halothane-induced liver injury in mice
-
Cheng L., You Q., Yin H., Holt M., Franklin C., Ju C. Effect of polyI:C cotreatment on halothane-induced liver injury in mice. J Hepatol 2009, 49(1):215-226.
-
(2009)
J Hepatol
, vol.49
, Issue.1
, pp. 215-226
-
-
Cheng, L.1
You, Q.2
Yin, H.3
Holt, M.4
Franklin, C.5
Ju, C.6
-
123
-
-
35448966687
-
The role of tumor necrosis factor alpha in lipopolysaccharide/ranitidine-induced inflammatory liver injury
-
Tukov F.F., Luyendyk J.P., Ganey P.E., Roth R.A. The role of tumor necrosis factor alpha in lipopolysaccharide/ranitidine-induced inflammatory liver injury. Toxicol Sci 2007, 100(1):267-280.
-
(2007)
Toxicol Sci
, vol.100
, Issue.1
, pp. 267-280
-
-
Tukov, F.F.1
Luyendyk, J.P.2
Ganey, P.E.3
Roth, R.A.4
-
124
-
-
70349330690
-
Sulindac metabolism and synergy with tumor necrosis factorα in a drug-inflammation interaction model of idiosyncratic liver injury
-
Zou W., Beggs K.M., Sparkenbaugh E.M., Jones A.D., Younis H.S., Roth R.A., et al. Sulindac metabolism and synergy with tumor necrosis factorα in a drug-inflammation interaction model of idiosyncratic liver injury. J Pharmacol Exp Ther 2009, 331(1):114-121.
-
(2009)
J Pharmacol Exp Ther
, vol.331
, Issue.1
, pp. 114-121
-
-
Zou, W.1
Beggs, K.M.2
Sparkenbaugh, E.M.3
Jones, A.D.4
Younis, H.S.5
Roth, R.A.6
-
125
-
-
70349294048
-
Trovafloxacin enhances TNF-induced inflammatory stress and cell death signaling and reduces TNF clearance in a murine model of idiosyncratic hepatotoxicity
-
Shaw P.J., Beggs K.M., Sparkenbaugh E.M., Dugan C.M., Ganey P.E., Roth R.A. Trovafloxacin enhances TNF-induced inflammatory stress and cell death signaling and reduces TNF clearance in a murine model of idiosyncratic hepatotoxicity. Toxicol Sci 2009, 111(2):288-301.
-
(2009)
Toxicol Sci
, vol.111
, Issue.2
, pp. 288-301
-
-
Shaw, P.J.1
Beggs, K.M.2
Sparkenbaugh, E.M.3
Dugan, C.M.4
Ganey, P.E.5
Roth, R.A.6
-
126
-
-
45749092159
-
P38 mitogen-activated protein kinase-dependent tumor necrosis factor-alpha-converting enzyme is important for liver injury in hepatotoxic interaction between lipopolysaccharide and ranitidine
-
Deng X., Lu J., Lehman-McKeeman L.D., Malle E., Crandall D.L., Ganey P.E., et al. p38 mitogen-activated protein kinase-dependent tumor necrosis factor-alpha-converting enzyme is important for liver injury in hepatotoxic interaction between lipopolysaccharide and ranitidine. J Pharmacol Exp Ther 2008, 326(1):144-152.
-
(2008)
J Pharmacol Exp Ther
, vol.326
, Issue.1
, pp. 144-152
-
-
Deng, X.1
Lu, J.2
Lehman-McKeeman, L.D.3
Malle, E.4
Crandall, D.L.5
Ganey, P.E.6
-
127
-
-
59149094002
-
Tumor necrosis factor alpha is a proximal mediator of synergistic hepatotoxicity from trovafloxacin/lipopolysaccharide coexposure
-
Shaw P.J., Ganey P.E., Roth R.A. Tumor necrosis factor alpha is a proximal mediator of synergistic hepatotoxicity from trovafloxacin/lipopolysaccharide coexposure. J Pharmacol Exp Ther 2009, 328(1):62-68.
-
(2009)
J Pharmacol Exp Ther
, vol.328
, Issue.1
, pp. 62-68
-
-
Shaw, P.J.1
Ganey, P.E.2
Roth, R.A.3
-
128
-
-
58049194180
-
Coexposure of mice to trovafloxacin and lipopolysaccharide, a model of idiosyncratic hepatotoxicity, results in a unique gene expression profile and interferon gamma-dependent liver injury
-
Shaw P.J., Ditewig A.C., Waring J.F., Liguori M.J., Blomme E.A., Ganey P.E., et al. Coexposure of mice to trovafloxacin and lipopolysaccharide, a model of idiosyncratic hepatotoxicity, results in a unique gene expression profile and interferon gamma-dependent liver injury. Toxicol Sci 2009, 107(1):270-280.
-
(2009)
Toxicol Sci
, vol.107
, Issue.1
, pp. 270-280
-
-
Shaw, P.J.1
Ditewig, A.C.2
Waring, J.F.3
Liguori, M.J.4
Blomme, E.A.5
Ganey, P.E.6
-
129
-
-
67349272258
-
Synergistic drug-cytokine induction of hepatocellular death as an in vitro approach for the study of inflammation-associated idiosyncratic drug hepatotoxicity
-
Cosgrove B.D., King B.M., Hasan M.A., Alexopoulos L.G., Farazi P.A., Hendriks B.S., et al. Synergistic drug-cytokine induction of hepatocellular death as an in vitro approach for the study of inflammation-associated idiosyncratic drug hepatotoxicity. Toxicol Appl Pharmacol 2009, 237(3):317-330.
-
(2009)
Toxicol Appl Pharmacol
, vol.237
, Issue.3
, pp. 317-330
-
-
Cosgrove, B.D.1
King, B.M.2
Hasan, M.A.3
Alexopoulos, L.G.4
Farazi, P.A.5
Hendriks, B.S.6
-
130
-
-
34547117370
-
Neutrophil interaction with the hemostatic system contributes to liver injury in rats cotreated with lipopolysaccharide and ranitidine
-
Deng X., Luyendyk J.P., Zou W., Lu J., Malle E., Ganey P.E., et al. Neutrophil interaction with the hemostatic system contributes to liver injury in rats cotreated with lipopolysaccharide and ranitidine. J Pharmacol Exp Ther 2007, 322(2):852-861.
-
(2007)
J Pharmacol Exp Ther
, vol.322
, Issue.2
, pp. 852-861
-
-
Deng, X.1
Luyendyk, J.P.2
Zou, W.3
Lu, J.4
Malle, E.5
Ganey, P.E.6
-
131
-
-
84858623486
-
Neutrophil-cytokine interactions in a rat model of sulindac-induced idiosyncratic liver injury
-
Zou W., Roth R.A., Younis H.S., Malle E., Ganey P.E. Neutrophil-cytokine interactions in a rat model of sulindac-induced idiosyncratic liver injury. J Toxicol 2011, 290(2-3):279-286.
-
(2011)
J Toxicol
, vol.290
, Issue.2-3
, pp. 279-286
-
-
Zou, W.1
Roth, R.A.2
Younis, H.S.3
Malle, E.4
Ganey, P.E.5
-
132
-
-
23944501121
-
Coagulation-mediated hypoxia and neutrophil-dependent hepatic injury in rats given lipopolysaccharide and ranitidine
-
Luyendyk J.P., Shaw P.J., Green C.D., Maddox J.F., Ganey P.E., Roth R.A. Coagulation-mediated hypoxia and neutrophil-dependent hepatic injury in rats given lipopolysaccharide and ranitidine. J Pharmacol Exp Ther 2005, 314:1023-1031.
-
(2005)
J Pharmacol Exp Ther
, vol.314
, pp. 1023-1031
-
-
Luyendyk, J.P.1
Shaw, P.J.2
Green, C.D.3
Maddox, J.F.4
Ganey, P.E.5
Roth, R.A.6
-
133
-
-
0024207188
-
Toxicity of phorbol myristate acetate-stimulated polymorphonuclear neutrophils against rat hepatocytes. Demonstration and mechanism
-
Guigui B., Rosenbaum J., Préaux A.M., Martin N., Zafrani E.S., Dhumeaux D., et al. Toxicity of phorbol myristate acetate-stimulated polymorphonuclear neutrophils against rat hepatocytes. Demonstration and mechanism. Lab Invest 1988, 59(6):831-837.
-
(1988)
Lab Invest
, vol.59
, Issue.6
, pp. 831-837
-
-
Guigui, B.1
Rosenbaum, J.2
Préaux, A.M.3
Martin, N.4
Zafrani, E.S.5
Dhumeaux, D.6
-
134
-
-
0029891492
-
Identification of factors from rat neutrophils responsible for cytotoxicity to isolated hepatocytes
-
Ho J.S., Buchweitz J.P., Roth R.A., Ganey P.E. Identification of factors from rat neutrophils responsible for cytotoxicity to isolated hepatocytes. J Leukoc Biol 1996, 59:716-724.
-
(1996)
J Leukoc Biol
, vol.59
, pp. 716-724
-
-
Ho, J.S.1
Buchweitz, J.P.2
Roth, R.A.3
Ganey, P.E.4
-
135
-
-
63649113233
-
The role of the hemostatic system in murine liver injury induced by coexposure to lipopolysaccharide and trovafloxacin, a drug with idiosyncratic liability
-
Shaw P.J., Fullerton A.M., Scott M.A., Ganey P.E., Roth R.A. The role of the hemostatic system in murine liver injury induced by coexposure to lipopolysaccharide and trovafloxacin, a drug with idiosyncratic liability. Toxicol Appl Pharmacol 2009, 236(3):293-300.
-
(2009)
Toxicol Appl Pharmacol
, vol.236
, Issue.3
, pp. 293-300
-
-
Shaw, P.J.1
Fullerton, A.M.2
Scott, M.A.3
Ganey, P.E.4
Roth, R.A.5
-
136
-
-
7444233368
-
Role of hepatic fibrin in idiosyncrasy-like liver injury from lipopolysaccharide-ranitidine coexposure in rats
-
Luyendyk J.P., Maddox J.F., Green C.D., Ganey P.E., Roth R.A. Role of hepatic fibrin in idiosyncrasy-like liver injury from lipopolysaccharide-ranitidine coexposure in rats. J Hepatol 2004, 40:1342-1351.
-
(2004)
J Hepatol
, vol.40
, pp. 1342-1351
-
-
Luyendyk, J.P.1
Maddox, J.F.2
Green, C.D.3
Ganey, P.E.4
Roth, R.A.5
-
137
-
-
57349168116
-
Gene expression profiles in livers from diclofenac-treated rats reveal intestinal bacteria-dependent and -independent pathways associated with liver injury
-
Deng X., Liguori M.J., Sparkenbaugh E.M., Waring J.F., Blomme E.A., Ganey P.E., et al. Gene expression profiles in livers from diclofenac-treated rats reveal intestinal bacteria-dependent and -independent pathways associated with liver injury. J Pharmacol Exp Ther 2008, 327(3):634-644.
-
(2008)
J Pharmacol Exp Ther
, vol.327
, Issue.3
, pp. 634-644
-
-
Deng, X.1
Liguori, M.J.2
Sparkenbaugh, E.M.3
Waring, J.F.4
Blomme, E.A.5
Ganey, P.E.6
-
138
-
-
77952878753
-
Oxidative stress is important in the pathogenesis of liver injury induced by sulindac and lipopolysaccharide cotreatment
-
Zou W., Roth R.A., Younis H.S., Burgoon L.D., Ganey P.E. Oxidative stress is important in the pathogenesis of liver injury induced by sulindac and lipopolysaccharide cotreatment. Toxicology 2010, 272:32-38.
-
(2010)
Toxicology
, vol.272
, pp. 32-38
-
-
Zou, W.1
Roth, R.A.2
Younis, H.S.3
Burgoon, L.D.4
Ganey, P.E.5
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