Neutrophil-cytokine interactions in a rat model of sulindac-induced idiosyncratic liver injury

Toxicology

Volumn 290, Issue 2-3, 2011, Pages 278-285

  Zou, Wei ^a,b   Roth, Robert A ^b,c   Younis, Husam S ^d   Malle, Ernst ^e   Ganey, Patricia E ^b,c  

^a Michigan State University ^*  (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

^c MICHIGAN STATE UNIVERSITY   (United States)

^d PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

^e MEDICAL UNIVERSITY OF GRAZ   (Austria)

Author keywords

Idiosyncratic drug induced liver injury; Lipopolysaccharide; Plasminogen activator inhibitor 1; Polymorphonuclear neutrophils; Sulindac; Tumor necrosis factor alpha

Indexed keywords

CYTOKINE; EGLIN C; FIBRIN; LIPOPOLYSACCHARIDE; PLASMINOGEN ACTIVATOR INHIBITOR 1; SULINDAC; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; COMPARATIVE STUDY; CONTROLLED STUDY; FIBRIN DEPOSITION; HEMOSTASIS; LEUKOCYTE ACTIVATION; MALE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; RAT; TOXIC HEPATITIS;

RATTUS;

EID: 84858623486     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2011.10.005     Document Type: Article

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