Acetaminophen-induced hepatic neutrophil accumulation and inflammatory liver injury in CD18-deficient mice

Liver International

Volumn 30, Issue 9, 2010, Pages 1280-1292

  Williams, Clarence David ^a   Bajt, Mary Lynn ^a   Farhood, Anwar ^b   Jaeschke, Hartmut ^a  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^b Brackenridge Hospital   (United States)

Author keywords

Acetaminophen; Drug hepatotoxicity; Inflammation; Innate immunity; Integrins; Neutrophils; Oxidant stress

Indexed keywords

CD11B ANTIGEN; CD18 ANTIGEN; CHEMOKINE; CYTOKINE; ENDOTOXIN; PARACETAMOL; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD; CELL DEATH; CELL FUNCTION; CELL ISOLATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE COURSE; DISEASE SEVERITY; INFLAMMATION; LIVER CELL; LIVER NECROSIS; LIVER TOXICITY; MALE; MOUSE; NEUTROPHIL; NONHUMAN; UPREGULATION; WILD TYPE;

ACETAMINOPHEN; ANALGESICS, NON-NARCOTIC; ANIMALS; ANTIGENS, CD18; BIOLOGICAL MARKERS; CHEMOKINES; DRUG-INDUCED LIVER INJURY; ENDOTOXINS; FEMALE; GENE EXPRESSION; HEPATOCYTES; INJECTIONS, INTRAPERITONEAL; LIVER; LIVER FUNCTION TESTS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NECROSIS; NEUTROPHILS; OXIDATIVE STRESS; RNA, MESSENGER;

EID: 78349236196     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/j.1478-3231.2010.02284.x     Document Type: Article

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