Bacterial- and viral-induced inflammation increases sensitivity to acetaminophen hepatotoxicity

Journal of Toxicology and Environmental Health - Part A: Current Issues

Volumn 73, Issue 1, 2010, Pages 58-73

  Maddox, Jane F ^a,b   Amuzie, Chidozie J ^a,b   Li, Maoxiang ^a   Newport, Sandra W ^a   Sparkenbaugh, Erica ^a,b   Cuff, Christopher F ^c   Pestka, James J ^a,b   Cantor, Glenn H ^d   Roth, Robert A ^a,b   Ganey, Patricia E ^a,b  

^a Department of Pharmacology and Toxicology ^*  (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

^c WEST VIRGINIA UNIVERSITY   (United States)

^d BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MACROPHAGE INHIBITORY PROTEIN 2; MESSENGER RNA; PARACETAMOL; PROTEIN; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR ALPHA ANTIBODY; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BACTERIAL INFECTION; CONTROLLED STUDY; DOSE RESPONSE; INFLAMMATION; LIVER TOXICITY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REOVIRUS; VIRUS INFECTION;

ACETAMINOPHEN; ANIMALS; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GLUTATHIONE; INFLAMMATION; LIPOPOLYSACCHARIDES; LIVER; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; NEUTROPHILS; REOVIRIDAE INFECTIONS; TUMOR NECROSIS FACTOR-ALPHA;

BACTERIA (MICROORGANISMS); MUS; ORTHOREOVIRUS;

EID: 71549150588     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/15287390903249057     Document Type: Article

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