-
1
-
-
0027751698
-
Hepatic and extrahepatic pathobiology of bacterial lipopolysaccharides
-
Hewett JA, Roth RA. Hepatic and extrahepatic pathobiology of bacterial lipopolysaccharides. Pharmacol Rev 1993;45:382-411.
-
(1993)
Pharmacol Rev
, vol.45
, pp. 382-411
-
-
Hewett, J.A.1
Roth, R.A.2
-
2
-
-
0035965951
-
Concurrent inflammation as a determinant of susceptibility to toxicity from xenobiotic agents
-
Ganey PE, Roth RA. Concurrent inflammation as a determinant of susceptibility to toxicity from xenobiotic agents. Toxicology 2001;169:195-208.
-
(2001)
Toxicology
, vol.169
, pp. 195-208
-
-
Ganey, P.E.1
Roth, R.A.2
-
4
-
-
0025970815
-
Side effects of ranitidine
-
Vial T, Goubier C, Bergeret A, Cabrera F, Evreux JC, Descotes J. Side effects of ranitidine. Drug Saf 1991;6:94-117.
-
(1991)
Drug Saf
, vol.6
, pp. 94-117
-
-
Vial, T.1
Goubier, C.2
Bergeret, A.3
Cabrera, F.4
Evreux, J.C.5
Descotes, J.6
-
5
-
-
0141563559
-
Ranitidine treatment during a modest inflammatory response precipitates idiosyncrasy-like liver injury in rats
-
Luyendyk JP, Maddox JF, Cosma GN, Ganey PE, Cockerell GL, Roth RA. Ranitidine treatment during a modest inflammatory response precipitates idiosyncrasy-like liver injury in rats. J Pharmacol Exp Ther 2003;307:9-16.
-
(2003)
J Pharmacol Exp Ther
, vol.307
, pp. 9-16
-
-
Luyendyk, J.P.1
Maddox, J.F.2
Cosma, G.N.3
Ganey, P.E.4
Cockerell, G.L.5
Roth, R.A.6
-
6
-
-
0028895655
-
The coagulation system, but not circulating fibrinogen, contributes to liver injury in rats exposed to lipopolysaccharide from gram-negative bacteria
-
Hewett JA, Roth RA. The coagulation system, but not circulating fibrinogen, contributes to liver injury in rats exposed to lipopolysaccharide from gram-negative bacteria. J Pharmacol Exp Ther 1995;272:53-62.
-
(1995)
J Pharmacol Exp Ther
, vol.272
, pp. 53-62
-
-
Hewett, J.A.1
Roth, R.A.2
-
7
-
-
0026578080
-
Neutrophil depletion protects against liver injury from bacterial endotoxin
-
Hewett JA, Schultze AE, VanCise S, Roth RA. Neutrophil depletion protects against liver injury from bacterial endotoxin. Lab Invest 1992;66:347-361.
-
(1992)
Lab Invest
, vol.66
, pp. 347-361
-
-
Hewett, J.A.1
Schultze, A.E.2
VanCise, S.3
Roth, R.A.4
-
8
-
-
0027729864
-
Relationship between tumor necrosis factor-alpha and neutrophils in endotoxin-induced liver injury
-
Hewett JA, Jean PA, Kunkel SL, Roth RA. Relationship between tumor necrosis factor-alpha and neutrophils in endotoxin-induced liver injury. Am J Physiol 1993;265(6 Pt 1):G1011-G1015.
-
(1993)
Am J Physiol
, vol.265
, Issue.6 PART 1
-
-
Hewett, J.A.1
Jean, P.A.2
Kunkel, S.L.3
Roth, R.A.4
-
9
-
-
0029366299
-
Platelet participation in liver injury from gram-negative bacterial lipopolysaccharide in the rat
-
Pearson JM, Schultze AE, Jean PA, Roth RA. Platelet participation in liver injury from gram-negative bacterial lipopolysaccharide in the rat. Shock 1995;4:178-186.
-
(1995)
Shock
, vol.4
, pp. 178-186
-
-
Pearson, J.M.1
Schultze, A.E.2
Jean, P.A.3
Roth, R.A.4
-
10
-
-
3242777001
-
Gene expression analysis points to hemostasis in livers of rats cotreated with lipopolysaccharide and ranitidine
-
Luyendyk JP, Mattes WB, Burgoon LD, Zacharewski TR, Maddox JF, Cosma GN, et al. Gene expression analysis points to hemostasis in livers of rats cotreated with lipopolysaccharide and ranitidine. Toxicol Sci 2004;80:203-213.
-
(2004)
Toxicol Sci
, vol.80
, pp. 203-213
-
-
Luyendyk, J.P.1
Mattes, W.B.2
Burgoon, L.D.3
Zacharewski, T.R.4
Maddox, J.F.5
Cosma, G.N.6
-
11
-
-
0002613087
-
Overview of hemostasis
-
Colman RW, Hirsh J, Marder VJ, Salzman EW, eds. Philadelphia, PA: Lippincott
-
Colman R. Overview of hemostasis. In: Colman RW, Hirsh J, Marder VJ, Salzman EW, eds. Hemostasis and Thrombosis. Philadelphia, PA: Lippincott, 1994:3.
-
(1994)
Hemostasis and Thrombosis
, pp. 3
-
-
Colman, R.1
-
12
-
-
0036158951
-
Endothelial cell injury and fibrin deposition in rat liver after monocrotaline exposure
-
Copple BL, Banes A, Ganey PE, Roth RA. Endothelial cell injury and fibrin deposition in rat liver after monocrotaline exposure. Toxicol Sci 2002;65:309-318.
-
(2002)
Toxicol Sci
, vol.65
, pp. 309-318
-
-
Copple, B.L.1
Banes, A.2
Ganey, P.E.3
Roth, R.A.4
-
13
-
-
0032079903
-
Reductive metabolism of the hypoxia marker pimonidazole is regulated by oxygen tension independent of the pyridine nucleotide redox state
-
Arteel GE, Thurman RG, Raleigh JA. Reductive metabolism of the hypoxia marker pimonidazole is regulated by oxygen tension independent of the pyridine nucleotide redox state. Eur J Biochem 1998;253:743-750.
-
(1998)
Eur J Biochem
, vol.253
, pp. 743-750
-
-
Arteel, G.E.1
Thurman, R.G.2
Raleigh, J.A.3
-
14
-
-
0028785458
-
Evidence that hypoxia markers detect oxygen gradients in liver: Pimonidazole and retrograde perfusion of rat liver
-
Arteel GE, Thurman RG, Yates JM, Raleigh JA. Evidence that hypoxia markers detect oxygen gradients in liver: pimonidazole and retrograde perfusion of rat liver. Br J Cancer 1995;72:889-895.
-
(1995)
Br J Cancer
, vol.72
, pp. 889-895
-
-
Arteel, G.E.1
Thurman, R.G.2
Yates, J.M.3
Raleigh, J.A.4
-
15
-
-
1642545520
-
Modes of cell death in rat liver after monocrotaline exposure
-
Copple BL, Rondelli CM, Maddox JF, Hoglen NC, Ganey PE, Roth RA. Modes of cell death in rat liver after monocrotaline exposure. Toxicol Sci 2004;77:172-182.
-
(2004)
Toxicol Sci
, vol.77
, pp. 172-182
-
-
Copple, B.L.1
Rondelli, C.M.2
Maddox, J.F.3
Hoglen, N.C.4
Ganey, P.E.5
Roth, R.A.6
-
16
-
-
0033233243
-
Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1
-
Semenza GL. Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1. Annu Rev Cell Dev Biol 1999;15:551-578.
-
(1999)
Annu Rev Cell Dev Biol
, vol.15
, pp. 551-578
-
-
Semenza, G.L.1
-
17
-
-
0035159670
-
HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxia
-
Stroka DM, Burkhardt T, Desbaillets I, Wenger RH, Neu DA, Bauer C, et al. HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxia. FASEB J 2001;15:2445-2453.
-
(2001)
FASEB J
, vol.15
, pp. 2445-2453
-
-
Stroka, D.M.1
Burkhardt, T.2
Desbaillets, I.3
Wenger, R.H.4
Neu, D.A.5
Bauer, C.6
-
18
-
-
0037480096
-
Endothelial cell injury and coagulation system activation during synergistic hepatotoxiciry from monocrotaline and bacterial lipopolysaccharide coexposure
-
Yee SB, Hanumegowda UM, Copple BL, Shibuya M, Ganey PE, Roth RA. Endothelial cell injury and coagulation system activation during synergistic hepatotoxiciry from monocrotaline and bacterial lipopolysaccharide coexposure. Toxicol Sci 2003;74:203-214.
-
(2003)
Toxicol Sci
, vol.74
, pp. 203-214
-
-
Yee, S.B.1
Hanumegowda, U.M.2
Copple, B.L.3
Shibuya, M.4
Ganey, P.E.5
Roth, R.A.6
-
19
-
-
0029822375
-
Degradation of cross-linked fibrin by matrix metalloproteinase 3 (stromelysin 1): Hydrolysis of the gamma Gly 404-Ala 405 peptidebond
-
Bini A, Itoh Y, Kudryk BJ, Nagase H. Degradation of cross-linked fibrin by matrix metalloproteinase 3 (stromelysin 1): hydrolysis of the gamma Gly 404-Ala 405 peptidebond. Biochemistry 1996;35:13056-13063.
-
(1996)
Biochemistry
, vol.35
, pp. 13056-13063
-
-
Bini, A.1
Itoh, Y.2
Kudryk, B.J.3
Nagase, H.4
-
20
-
-
0037343115
-
Augmentation of aflatoxin B1 hepatotoxicity by endotoxin: Involvement of endothelium and the coagulation system
-
Luyendyk JP, Copple BL, Barton CC, Ganey PE, Roth RA. Augmentation of aflatoxin B1 hepatotoxicity by endotoxin: involvement of endothelium and the coagulation system. Toxicol Sci 2003;72:171-181.
-
(2003)
Toxicol Sci
, vol.72
, pp. 171-181
-
-
Luyendyk, J.P.1
Copple, B.L.2
Barton, C.C.3
Ganey, P.E.4
Roth, R.A.5
-
21
-
-
0033697108
-
Regulation of plasminogen activator inhibitor-1 and urokinase by hyaluronan fragments in mouse macrophages
-
Horton MR, Olman MA, Bao C, White KE, Choi AM, Chin BY, et al. Regulation of plasminogen activator inhibitor-1 and urokinase by hyaluronan fragments in mouse macrophages. Am J Physiol Lung Cell Mol Physiol 2000;279:L707-L715.
-
(2000)
Am J Physiol Lung Cell Mol Physiol
, vol.279
-
-
Horton, M.R.1
Olman, M.A.2
Bao, C.3
White, K.E.4
Choi, A.M.5
Chin, B.Y.6
-
22
-
-
0036544849
-
Plasminogen activator inhibitor 1: Physiological and pathophysiological roles
-
Binder BR, Christ G, Gruber F, Grubic N, Hufnagl P, Krebs M, et al. Plasminogen activator inhibitor 1: physiological and pathophysiological roles. News Physiol Sci 2002;17:56-61.
-
(2002)
News Physiol Sci
, vol.17
, pp. 56-61
-
-
Binder, B.R.1
Christ, G.2
Gruber, F.3
Grubic, N.4
Hufnagl, P.5
Krebs, M.6
-
23
-
-
0344737033
-
Tumor necrosis factor-(alpha) and troglitazone regulate plasminogen activator inhibitor type 1 production through extracellular signal-regulated kinase- and nuclear factor-{kappa}B-dependent pathways in cultured human umbilical vein endothelial cells
-
Hamaguchi E, Takamura T, Shimizu A, Nagai Y. Tumor necrosis factor-(alpha) and troglitazone regulate plasminogen activator inhibitor type 1 production through extracellular signal-regulated kinase- and nuclear factor-{kappa}B-dependent pathways in cultured human umbilical vein endothelial cells. J Pharmacol Exp Ther 2003;307:987-994.
-
(2003)
J Pharmacol Exp Ther
, vol.307
, pp. 987-994
-
-
Hamaguchi, E.1
Takamura, T.2
Shimizu, A.3
Nagai, Y.4
-
24
-
-
0025949379
-
Regulation of murine type 1 plasminogen activator inhibitor gene expression in vivo: Tissue specificity and induction by lipopolysaccharide, tumor necrosis factor-alpha, and transforming growth factor-beta
-
Sawdey MS, Loskutoff DJ. Regulation of murine type 1 plasminogen activator inhibitor gene expression in vivo: tissue specificity and induction by lipopolysaccharide, tumor necrosis factor-alpha, and transforming growth factor-beta. J Clin Invest 1991;88:1346-1353.
-
(1991)
J Clin Invest
, vol.88
, pp. 1346-1353
-
-
Sawdey, M.S.1
Loskutoff, D.J.2
-
25
-
-
0033916564
-
Prevention of renal fibrin deposition in endotoxin-induced DIC through inhibition of PAI-1
-
Montes R, Declerck PJ, Calvo A, Montes M, Hermida J, Munoz MC, et al. Prevention of renal fibrin deposition in endotoxin-induced DIC through inhibition of PAI-1. Thromb Haemost 2000;84:65-70.
-
(2000)
Thromb Haemost
, vol.84
, pp. 65-70
-
-
Montes, R.1
Declerck, P.J.2
Calvo, A.3
Montes, M.4
Hermida, J.5
Munoz, M.C.6
-
26
-
-
0030034227
-
Anti-thrombotic effect of a PAI-1 inhibitor in rats given endotoxin
-
Abrahamsson T, Nerme V, Stromqvist M, Akerblom B, Legnehed A, Pettersson K, et al. Anti-thrombotic effect of a PAI-1 inhibitor in rats given endotoxin. Thromb Haemost 1996;75:118-126.
-
(1996)
Thromb Haemost
, vol.75
, pp. 118-126
-
-
Abrahamsson, T.1
Nerme, V.2
Stromqvist, M.3
Akerblom, B.4
Legnehed, A.5
Pettersson, K.6
-
27
-
-
0141791316
-
Fibrinolysis in LPS-induced chronic airway disease
-
Savov JD, Brass DM, Berman KG, McElvania E, Schwartz DA. Fibrinolysis in LPS-induced chronic airway disease. Am J Physiol Lung Cell Mol Physiol 2003;285:L940-L948.
-
(2003)
Am J Physiol Lung Cell Mol Physiol
, vol.285
-
-
Savov, J.D.1
Brass, D.M.2
Berman, K.G.3
McElvania, E.4
Schwartz, D.A.5
-
28
-
-
0023755059
-
Intravascular coagulation in acute liver failure in rats and its treatment with anti-thrombin III
-
Fujiwara K, Ogata I, Ohta Y, Hirata K, Oka Y, Yamada S, et al. Intravascular coagulation in acute liver failure in rats and its treatment with anti-thrombin III. Gut 1988;29:1103-1108.
-
(1988)
Gut
, vol.29
, pp. 1103-1108
-
-
Fujiwara, K.1
Ogata, I.2
Ohta, Y.3
Hirata, K.4
Oka, Y.5
Yamada, S.6
-
29
-
-
0036566445
-
Anticoagulants prevent monocrotaline-induced hepatic parenchymal cell injury but not endothelial cell injury in the rat
-
Copple BL, Woolley B, Banes A, Ganey PE, Roth RA. Anticoagulants prevent monocrotaline-induced hepatic parenchymal cell injury but not endothelial cell injury in the rat. Toxicol Appl Pharmacol 2002;180:186-196.
-
(2002)
Toxicol Appl Pharmacol
, vol.180
, pp. 186-196
-
-
Copple, B.L.1
Woolley, B.2
Banes, A.3
Ganey, P.E.4
Roth, R.A.5
-
30
-
-
0043092127
-
The coagulation system contributes to synergistic liver injury from exposure to monocrotaline and bacterial lipopolysaccharide
-
Yee SB, Harkema JR, Ganey PE, Roth RA. The coagulation system contributes to synergistic liver injury from exposure to monocrotaline and bacterial lipopolysaccharide. Toxicol Sci 2003;74:457-469.
-
(2003)
Toxicol Sci
, vol.74
, pp. 457-469
-
-
Yee, S.B.1
Harkema, J.R.2
Ganey, P.E.3
Roth, R.A.4
-
31
-
-
0036772790
-
Enhancement of allyl alcohol hepatotoxicity by endotoxin requires extrahepatic factors
-
Kinser S, Copple BL, Roth RA, Ganey PE. Enhancement of allyl alcohol hepatotoxicity by endotoxin requires extrahepatic factors. Toxicol Sci 2002;69:470-481.
-
(2002)
Toxicol Sci
, vol.69
, pp. 470-481
-
-
Kinser, S.1
Copple, B.L.2
Roth, R.A.3
Ganey, P.E.4
-
32
-
-
0030435119
-
The thrombin inhibitor, hirudin, attenuates lipopolysaccharide-induced liver injury in the rat
-
Pearson JM, Schultze AE, Schwanz KA, Scott MA, Davis JM, Roth RA. The thrombin inhibitor, hirudin, attenuates lipopolysaccharide-induced liver injury in the rat. J Pharmacol Exp Ther 1996;278:378-383.
-
(1996)
J Pharmacol Exp Ther
, vol.278
, pp. 378-383
-
-
Pearson, J.M.1
Schultze, A.E.2
Schwanz, K.A.3
Scott, M.A.4
Davis, J.M.5
Roth, R.A.6
-
33
-
-
10644255069
-
Hypoxia in rat liver after monocrotaline exposure
-
Copple BL, Ganey PE, Roth RA. Hypoxia in rat liver after monocrotaline exposure [Abstract]. Toxicol Sci 2004;78(S-1):491.
-
(2004)
Toxicol Sci
, vol.78
, Issue.S-1
, pp. 491
-
-
Copple, B.L.1
Ganey, P.E.2
Roth, R.A.3
-
34
-
-
0023676175
-
Early midzonal cell death during low-flow hypoxia in the isolated, perfused rat liver: Protection by allopurinol
-
Marotto ME, Thurman RG, Lemasters JJ. Early midzonal cell death during low-flow hypoxia in the isolated, perfused rat liver: protection by allopurinol. HEPATOLOGY 1988;8:585-590.
-
(1988)
Hepatology
, vol.8
, pp. 585-590
-
-
Marotto, M.E.1
Thurman, R.G.2
Lemasters, J.J.3
-
35
-
-
0019807592
-
Centrilobular injury following hypoxia in isolated, perfused rat liver
-
Lemasters JJ, Ji S, Thurman RG. Centrilobular injury following hypoxia in isolated, perfused rat liver. Science 1981;213:661-663.
-
(1981)
Science
, vol.213
, pp. 661-663
-
-
Lemasters, J.J.1
Ji, S.2
Thurman, R.G.3
-
36
-
-
0023248631
-
Enhanced hepatotoxicity of endotoxin by hypoxia
-
Shibayama Y. Enhanced hepatotoxicity of endotoxin by hypoxia. Pathol Res Pract 1987;182:390-395.
-
(1987)
Pathol Res Pract
, vol.182
, pp. 390-395
-
-
Shibayama, Y.1
-
37
-
-
0021210573
-
Ranitidine and haemostasis in man
-
Stadnicki A. Ranitidine and haemostasis in man. Hepatogastroenterology 1984;31:230-232.
-
(1984)
Hepatogastroenterology
, vol.31
, pp. 230-232
-
-
Stadnicki, A.1
-
38
-
-
0041931019
-
Clinical pharmacology consultations: Consultation requests may be misleading - An organized approach to drug-induced hepatitis
-
Valois M, Cooper MA, Shear NH. Clinical pharmacology consultations: consultation requests may be misleading - an organized approach to drug-induced hepatitis. Can J Clin Pharmacol 2003;10:59-62.
-
(2003)
Can J Clin Pharmacol
, vol.10
, pp. 59-62
-
-
Valois, M.1
Cooper, M.A.2
Shear, N.H.3
-
39
-
-
0034161456
-
Role of hemostatic gene polymorphisms in venous and arterial thrombotic disease
-
Lane DA, Grant PJ. Role of hemostatic gene polymorphisms in venous and arterial thrombotic disease. Blood 2000;95:1517-1532.
-
(2000)
Blood
, vol.95
, pp. 1517-1532
-
-
Lane, D.A.1
Grant, P.J.2
-
41
-
-
0035897712
-
Metabolic, idiosyncratic toxicity of drugs: Overview of the hepatic toxicity induced by the anxiolytic, panadiplon
-
Ulrich RG, Bacon JA, Brass EP, Cramer CT, Petrella DK, Sun EL. Metabolic, idiosyncratic toxicity of drugs: overview of the hepatic toxicity induced by the anxiolytic, panadiplon. Chemico-Biol Interact 2001;134:251-270.
-
(2001)
Chemico-Biol Interact
, vol.134
, pp. 251-270
-
-
Ulrich, R.G.1
Bacon, J.A.2
Brass, E.P.3
Cramer, C.T.4
Petrella, D.K.5
Sun, E.L.6
-
42
-
-
0029989532
-
Potentiation of hypoxic injury in cultured rabbit hepatocytes by the quinoxalinone anxiolytic, panadiplon
-
Bacon JA, Cramer CT, Petrella DK, Sun EL, Ulrich RG. Potentiation of hypoxic injury in cultured rabbit hepatocytes by the quinoxalinone anxiolytic, panadiplon. Toxicology 1996;108:9-16.
-
(1996)
Toxicology
, vol.108
, pp. 9-16
-
-
Bacon, J.A.1
Cramer, C.T.2
Petrella, D.K.3
Sun, E.L.4
Ulrich, R.G.5
|