메뉴 건너뛰기




Volumn 22, Issue 2, 2003, Pages 146-161

Involvement of two different cell death pathways in retinal atrophy of cathepsin D-deficient mice

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 9; CATHEPSIN B; CATHEPSIN D; CATHEPSIN L; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR;

EID: 0037301337     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1044-7431(03)00035-6     Document Type: Article
Times cited : (135)

References (66)
  • 1
    • 0035449358 scopus 로고    scopus 로고
    • Inflammatory neurodegeneration mediated by nitric oxide from activated glia-inhibiting neuronal respiration, causing glutamate release and excitotoxicity
    • Bal-Price A., Brown G.C. Inflammatory neurodegeneration mediated by nitric oxide from activated glia-inhibiting neuronal respiration, causing glutamate release and excitotoxicity. J. Neurosci. 21:2001;6480-6491.
    • (2001) J. Neurosci. , vol.21 , pp. 6480-6491
    • Bal-Price, A.1    Brown, G.C.2
  • 2
    • 0022742338 scopus 로고
    • Purification and tissue distribution of rat cathepsin L
    • Bando Y., Kominami E., Katunuma N. Purification and tissue distribution of rat cathepsin L. J. Biochem. (Tokyo). 100:1986;35-42.
    • (1986) J. Biochem. (Tokyo) , vol.100 , pp. 35-42
    • Bando, Y.1    Kominami, E.2    Katunuma, N.3
  • 3
    • 0033762747 scopus 로고    scopus 로고
    • Histopathologic and immunocytochemical analysis of the retina and ocular tissues in Batten disease
    • Bensaoula T., Shibuya H., Katz M.L., Smith J.E., Johnson G.S., John S.K., Milam A.H. Histopathologic and immunocytochemical analysis of the retina and ocular tissues in Batten disease. Ophthalmology. 107:2000;1746-1753.
    • (2000) Ophthalmology , vol.107 , pp. 1746-1753
    • Bensaoula, T.1    Shibuya, H.2    Katz, M.L.3    Smith, J.E.4    Johnson, G.S.5    John, S.K.6    Milam, A.H.7
  • 4
    • 0024535608 scopus 로고
    • Cell type-specific distribution of cathepsin B and D immunoreactivity within the rabbit retina
    • Bernstein H.G., Reichenbach A., Kirschke H., Wiederanders B. Cell type-specific distribution of cathepsin B and D immunoreactivity within the rabbit retina. Neurosci. Lett. 98:1989;135-138.
    • (1989) Neurosci. Lett. , vol.98 , pp. 135-138
    • Bernstein, H.G.1    Reichenbach, A.2    Kirschke, H.3    Wiederanders, B.4
  • 5
    • 0024251647 scopus 로고
    • Clinical classification of neuronal ceroid-lipofuscinosis subtypes
    • Boustany R.M., Alroy J., Kolodny E.H. Clinical classification of neuronal ceroid-lipofuscinosis subtypes. Am J. Med. Genet. 5:(Suppl.):1988;47-58.
    • (1988) Am J. Med. Genet. , vol.5 , Issue.SUPPL. , pp. 47-58
    • Boustany, R.M.1    Alroy, J.2    Kolodny, E.H.3
  • 6
    • 0028134892 scopus 로고
    • Nanomolar concentrations of nitric oxide reversibly inhibit synaptosomal respiration by competing with oxygen at cytochrome oxidase
    • Brown G.C., Cooper C.E. Nanomolar concentrations of nitric oxide reversibly inhibit synaptosomal respiration by competing with oxygen at cytochrome oxidase. FEBS Lett. 356:1994;295-298.
    • (1994) FEBS Lett. , vol.356 , pp. 295-298
    • Brown, G.C.1    Cooper, C.E.2
  • 7
    • 0024223513 scopus 로고
    • Morphological diagnosis and misdiagnosis in Batten-Kufs disease
    • Carpenter S. Morphological diagnosis and misdiagnosis in Batten-Kufs disease. Am J. Med. Genet. 5:(Suppl.):1988;85-91.
    • (1988) Am J. Med. Genet. , vol.5 , Issue.SUPPL. , pp. 85-91
    • Carpenter, S.1
  • 9
    • 0027521914 scopus 로고
    • Apoptosis: Final common pathway of photoreceptor death in rd, rds, and rhodopsin mutant mice
    • Chang G.Q., Hao Y., Wong F. Apoptosis final common pathway of photoreceptor death in rd, rds, and rhodopsin mutant mice . Neuron. 11:1993;595-605.
    • (1993) Neuron , vol.11 , pp. 595-605
    • Chang, G.Q.1    Hao, Y.2    Wong, F.3
  • 11
    • 17644432297 scopus 로고    scopus 로고
    • Recent advances in the molecular basis of inherited photoreceptor degeneration
    • Clarke G., Heon E., McInnes R.R. Recent advances in the molecular basis of inherited photoreceptor degeneration. Clin. Genet. 57:2000;313-329.
    • (2000) Clin. Genet. , vol.57 , pp. 313-329
    • Clarke, G.1    Heon, E.2    McInnes, R.R.3
  • 12
    • 0032900931 scopus 로고    scopus 로고
    • Detection of genomic DNA fragmentation during apoptosis (DNA ladder) and the simultaneous isolation of RNA from low cell numbers
    • Daniel P.T., aSturm I., Ritschel S., Friedrich K., Dorken B., Bendzko P., Hillebrand T. Detection of genomic DNA fragmentation during apoptosis (DNA ladder) and the simultaneous isolation of RNA from low cell numbers. Anal. Biochem. 266:1999;110-115.
    • (1999) Anal. Biochem. , vol.266 , pp. 110-115
    • Daniel, P.T.1    ASturm, I.2    Ritschel, S.3    Friedrich, K.4    Dorken, B.5    Bendzko, P.6    Hillebrand, T.7
  • 13
    • 0032516003 scopus 로고    scopus 로고
    • Cathepsins B and D are dispensable for major histocompatibility complex class II-mediated antigen presentation
    • Deussing J., Roth W., Saftig P., Peters C., Ploegh H.L., Villadangos J.A. Cathepsins B and D are dispensable for major histocompatibility complex class II-mediated antigen presentation. Proc. Natl. Acad. Sci. USA. 95:1998;4516-4521.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 4516-4521
    • Deussing, J.1    Roth, W.2    Saftig, P.3    Peters, C.4    Ploegh, H.L.5    Villadangos, J.A.6
  • 14
    • 0025290956 scopus 로고
    • The sequence of the major protein stored in ovine ceroid lipofuscinosis is identical with that of the dicyclohexylcarbodiimide-reactive proteolipid of mitochondrial ATP synthase
    • Fearnley I.M., Walker J.E., Martinus R.D., Jolly R.D., Kirkland K.B., Shaw G.J., Palmer D.N. The sequence of the major protein stored in ovine ceroid lipofuscinosis is identical with that of the dicyclohexylcarbodiimide-reactive proteolipid of mitochondrial ATP synthase. Biochem. J. 268:1990;751-758.
    • (1990) Biochem. J. , vol.268 , pp. 751-758
    • Fearnley, I.M.1    Walker, J.E.2    Martinus, R.D.3    Jolly, R.D.4    Kirkland, K.B.5    Shaw, G.J.6    Palmer, D.N.7
  • 16
    • 0026648674 scopus 로고
    • Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
    • Gavrieli Y., Sherman Y., Ben-Sasson S.A. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol. 119:1992;493-501.
    • (1992) J Cell Biol. , vol.119 , pp. 493-501
    • Gavrieli, Y.1    Sherman, Y.2    Ben-Sasson, S.A.3
  • 17
    • 0026530291 scopus 로고
    • Retina in various animal models of neuronal ceroid-lipofuscinosis
    • Goebel H.H. Retina in various animal models of neuronal ceroid-lipofuscinosis. Am J. Med. Genet. 42:1992;605-608.
    • (1992) Am J. Med. Genet. , vol.42 , pp. 605-608
    • Goebel, H.H.1
  • 18
    • 0023928225 scopus 로고
    • Ultrastructural studies of the retina in infantile neuronal ceroid-lipofus-cinosis
    • Goebel H.H., Klein H., Santavuori P., Sainio K. Ultrastructural studies of the retina in infantile neuronal ceroid-lipofus-cinosis. Retina. 8:1988;59-66.
    • (1988) Retina , vol.8 , pp. 59-66
    • Goebel, H.H.1    Klein, H.2    Santavuori, P.3    Sainio, K.4
  • 19
    • 0031773434 scopus 로고    scopus 로고
    • Ultrastructure of the retina in adult neuronal ceroid lipofuscinosis
    • Goebel H.H., Schochet S.S., Jaynes M., Gutmann L. Ultrastructure of the retina in adult neuronal ceroid lipofuscinosis. Acta Anat. (Basel). 162:1998;127-132.
    • (1998) Acta Anat. (Basel) , vol.162 , pp. 127-132
    • Goebel, H.H.1    Schochet, S.S.2    Jaynes, M.3    Gutmann, L.4
  • 21
    • 0025854327 scopus 로고
    • Lysosomal storage of subunit c of mitochondrial ATP synthase in Batten's disease (ceroid-lipofuscinosis)
    • Hall N.A., Lake B.D., Dewji N.N., Patrick A.D. Lysosomal storage of subunit c of mitochondrial ATP synthase in Batten's disease (ceroid-lipofuscinosis). Biochem. J. 275:1991;269-272.
    • (1991) Biochem. J. , vol.275 , pp. 269-272
    • Hall, N.A.1    Lake, B.D.2    Dewji, N.N.3    Patrick, A.D.4
  • 22
    • 0033536944 scopus 로고    scopus 로고
    • Rods and cones project to the inner plexiform layer during development
    • Johnson P.T., Williams R.R., Cusato K., Reese B.E. Rods and cones project to the inner plexiform layer during development. J Comp. Neurol. 414:1999;1-12.
    • (1999) J Comp. Neurol. , vol.414 , pp. 1-12
    • Johnson, P.T.1    Williams, R.R.2    Cusato, K.3    Reese, B.E.4
  • 23
    • 0035159897 scopus 로고    scopus 로고
    • Characterization of cell death pathways in murine retinal neurodegeneration implicates cytochrome c release, caspase activation, and bid cleavage
    • Jomary C., Neal M.J., Jones S.E. Characterization of cell death pathways in murine retinal neurodegeneration implicates cytochrome c release, caspase activation, and bid cleavage. Mol. Cell. Neurosci. 18:2001;335-346.
    • (2001) Mol. Cell. Neurosci. , vol.18 , pp. 335-346
    • Jomary, C.1    Neal, M.J.2    Jones, S.E.3
  • 24
    • 0034916518 scopus 로고    scopus 로고
    • Mouse gene knockout models for the CLN2 and CLN3 forms of ceroid lipofuscinosis
    • Katz M.L., Johnson G.S. Mouse gene knockout models for the CLN2 and CLN3 forms of ceroid lipofuscinosis. Eur. J. Paediatr. Neurol. 5:(Suppl. A):2001;109-114.
    • (2001) Eur. J. Paediatr. Neurol. , vol.5 , Issue.SUPPL. A , pp. 109-114
    • Katz, M.L.1    Johnson, G.S.2
  • 25
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr J.F., Wyllie A.H., Currie A.R. Apoptosis a basic biological phenomenon with wide-ranging implications in tissue kinetics . Br J. Cancer. 26:1972;239-257.
    • (1972) Br J. Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.1    Wyllie, A.H.2    Currie, A.R.3
  • 27
    • 0021687268 scopus 로고
    • Increases in cathepsins B and L and thiol proteinase inhibitor in muscle of dystrophic hamsters. Their localization in invading phagocytes
    • Kominami E., Bando Y., Ii K., Hizawa K., Katunuma N. Increases in cathepsins B and L and thiol proteinase inhibitor in muscle of dystrophic hamsters. Their localization in invading phagocytes. J Biochem. (Tokyo). 96:1984;1841-1848.
    • (1984) J Biochem. (Tokyo) , vol.96 , pp. 1841-1848
    • Kominami, E.1    Bando, Y.2    Ii, K.3    Hizawa, K.4    Katunuma, N.5
  • 28
    • 0026526712 scopus 로고
    • Specific storage of subunit c of mitochondrial ATP synthase in lysosomes of neuronal ceroid lipofuscinosis (Batten's disease)
    • Kominami E., Ezaki J., Muno D., Ishido K., Ueno T., Wolfe L.S. Specific storage of subunit c of mitochondrial ATP synthase in lysosomes of neuronal ceroid lipofuscinosis (Batten's disease). J Biochem. (Tokyo). 111:1992;278-282.
    • (1992) J Biochem. (Tokyo) , vol.111 , pp. 278-282
    • Kominami, E.1    Ezaki, J.2    Muno, D.3    Ishido, K.4    Ueno, T.5    Wolfe, L.S.6
  • 29
    • 0021875579 scopus 로고
    • Distribution of cathepsins B and H in rat tissues and peripheral blood cells
    • Kominami E., Tsukahara T., Bando Y., Katunuma N. Distribution of cathepsins B and H in rat tissues and peripheral blood cells. J Biochem. (Tokyo). 98:1985;87-93.
    • (1985) J Biochem. (Tokyo) , vol.98 , pp. 87-93
    • Kominami, E.1    Tsukahara, T.2    Bando, Y.3    Katunuma, N.4
  • 33
    • 0033973197 scopus 로고    scopus 로고
    • The use of adenovirus-mediated gene transfer to develop a rat model for photoreceptor degeneration
    • Lai C.M., Shen W.Y., Constable I., Rakoczy P.E. The use of adenovirus-mediated gene transfer to develop a rat model for photoreceptor degeneration. Invest. Ophthalmol. Vis. Sci. 41:2000;580-584.
    • (2000) Invest. Ophthalmol. Vis. Sci. , vol.41 , pp. 580-584
    • Lai, C.M.1    Shen, W.Y.2    Constable, I.3    Rakoczy, P.E.4
  • 35
    • 0030860241 scopus 로고    scopus 로고
    • Peroxynitrite and nitric oxide donors induce neuronal apoptosis by eliciting autocrine excitotoxicity
    • Leist M., Fava E., Montecucco C., Nicotera P. Peroxynitrite and nitric oxide donors induce neuronal apoptosis by eliciting autocrine excitotoxicity. Eur. J Neurosci. 9:1997;1488-1498.
    • (1997) Eur. J Neurosci. , vol.9 , pp. 1488-1498
    • Leist, M.1    Fava, E.2    Montecucco, C.3    Nicotera, P.4
  • 36
    • 0033564046 scopus 로고    scopus 로고
    • Activation of caspase-3 in the retina of transgenic rats with the rhodopsin mutation s334ter during photoreceptor degeneration
    • Liu C., Li Y., Peng M., Laties A.M., Wen R. Activation of caspase-3 in the retina of transgenic rats with the rhodopsin mutation s334ter during photoreceptor degeneration. J Neurosci. 19:1999;4778-4785.
    • (1999) J Neurosci. , vol.19 , pp. 4778-4785
    • Liu, C.1    Li, Y.2    Peng, M.3    Laties, A.M.4    Wen, R.5
  • 38
    • 0034630317 scopus 로고    scopus 로고
    • Apoptotic DNA fragmentation
    • Nagata S. Apoptotic DNA fragmentation. Exp. Cell Res. 256:2000;12-18.
    • (2000) Exp. Cell Res. , vol.256 , pp. 12-18
    • Nagata, S.1
  • 41
    • 0028924890 scopus 로고
    • Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis
    • Nitatori T., Sato N., Waguri S., Karasawa Y., Araki H., Shibanai K., Kominami E., Uchiyama Y. Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis. J Neurosci. 15:1995;1001-1011.
    • (1995) J Neurosci. , vol.15 , pp. 1001-1011
    • Nitatori, T.1    Sato, N.2    Waguri, S.3    Karasawa, Y.4    Araki, H.5    Shibanai, K.6    Kominami, E.7    Uchiyama, Y.8
  • 42
    • 0032455357 scopus 로고    scopus 로고
    • An ultrastructural and immunohistochemical study of PC12 cells during apoptosis induced by serum deprivation with special reference to autophagy and lysosomal cathepsins
    • Ohsawa Y., Isahara K., Kanamori S., Shibata M., Kametaka S., Gotow T., Watanabe T., Kominami E., Uchiyama Y. An ultrastructural and immunohistochemical study of PC12 cells during apoptosis induced by serum deprivation with special reference to autophagy and lysosomal cathepsins. Arch. Histol. Cytol. 61:1998;395-403.
    • (1998) Arch. Histol. Cytol. , vol.61 , pp. 395-403
    • Ohsawa, Y.1    Isahara, K.2    Kanamori, S.3    Shibata, M.4    Kametaka, S.5    Gotow, T.6    Watanabe, T.7    Kominami, E.8    Uchiyama, Y.9
  • 43
    • 0027243863 scopus 로고
    • Lysosomal cysteine and aspartic proteinases, acid phosphatase, and an endogenous cyteine proteinase inhibitor, cystatin b in rat osteoclasts
    • Ohsawa Y., Nitatori T., Sato N., Waguri S., Higuchi S., Ishido K., Kominami E., Uchiyama Y. Lysosomal cysteine and aspartic proteinases, acid phosphatase, and an endogenous cyteine proteinase inhibitor, cystatin b in rat osteoclasts. J Histochem. Cytochem. 41:1993;1075-1083.
    • (1993) J Histochem. Cytochem. , vol.41 , pp. 1075-1083
    • Ohsawa, Y.1    Nitatori, T.2    Sato, N.3    Waguri, S.4    Higuchi, S.5    Ishido, K.6    Kominami, E.7    Uchiyama, Y.8
  • 44
    • 0034052318 scopus 로고    scopus 로고
    • Growth factors in combination, but not individually, rescue rd mouse photoreceptors in organ culture
    • Ogilvie J.M., Speck J.D., Lett J.M. Growth factors in combination, but not individually, rescue rd mouse photoreceptors in organ culture. Exp. Neurol. 161:2000;676-685.
    • (2000) Exp. Neurol. , vol.161 , pp. 676-685
    • Ogilvie, J.M.1    Speck, J.D.2    Lett, J.M.3
  • 45
    • 0024511783 scopus 로고
    • Ovine ceroid lipofuscinosis. The major lipopigment protein and the lipid-binding subunit of mitochondrial ATP synthase have the same NH2-terminal sequence
    • Palmer D.N., Martinus R.D., Cooper S.M., Midwinter G.G., Reid J.C., Jolly R.D. Ovine ceroid lipofuscinosis. The major lipopigment protein and the lipid-binding subunit of mitochondrial ATP synthase have the same NH2-terminal sequence. J Biol. Chem. 264:1989;5736-5740.
    • (1989) J Biol. Chem. , vol.264 , pp. 5736-5740
    • Palmer, D.N.1    Martinus, R.D.2    Cooper, S.M.3    Midwinter, G.G.4    Reid, J.C.5    Jolly, R.D.6
  • 46
    • 0034174478 scopus 로고    scopus 로고
    • Analysis of expressed sequence tags of retinal pigment epithelium: Cystatin C is an abundant transcript
    • Paraoan L., Grierson I., Maden B.E. Analysis of expressed sequence tags of retinal pigment epithelium Cystatin C is an abundant transcript . Int. J Biochem. Cell. Biol. 32:2000;417-426.
    • (2000) Int. J Biochem. Cell. Biol. , vol.32 , pp. 417-426
    • Paraoan, L.1    Grierson, I.2    Maden, B.E.3
  • 49
    • 0032886890 scopus 로고    scopus 로고
    • Distribution of cathepsin D in human eyes with or without age related maculopathy
    • Rakoczy P.E., Sarks S.H., Daw N., Constable I.J. Distribution of cathepsin D in human eyes with or without age related maculopathy. Exp. Eye Res. 69:1999;367-374.
    • (1999) Exp. Eye Res. , vol.69 , pp. 367-374
    • Rakoczy, P.E.1    Sarks, S.H.2    Daw, N.3    Constable, I.J.4
  • 50
    • 0026596841 scopus 로고
    • Perspective of biochemical research in the neuronal ceroid-lipofuscinosis
    • Rider J.A., Dawson G., Siakotos A.N. Perspective of biochemical research in the neuronal ceroid-lipofuscinosis. Am J. Med. Genet. 42:1992;519-524.
    • (1992) Am J. Med. Genet. , vol.42 , pp. 519-524
    • Rider, J.A.1    Dawson, G.2    Siakotos, A.N.3
  • 51
  • 53
    • 0029083689 scopus 로고
    • Mice deficient for the lysosomal proteinase cathepsin D exhibit progressive atrophy of the intestinal mucosa and profound destruction of lymphoid cells
    • Saftig P., Hetman M., Schmahl W., Weber K., Heine L., Mossmann H., Koster A., Hess B., Evers M., von Figura K. Mice deficient for the lysosomal proteinase cathepsin D exhibit progressive atrophy of the intestinal mucosa and profound destruction of lymphoid cells. EMBO J. 14:1995;3599-3608.
    • (1995) EMBO J. , vol.14 , pp. 3599-3608
    • Saftig, P.1    Hetman, M.2    Schmahl, W.3    Weber, K.4    Heine, L.5    Mossmann, H.6    Koster, A.7    Hess, B.8    Evers, M.9    Von Figura, K.10
  • 54
    • 0029970783 scopus 로고    scopus 로고
    • Amyloidogenic processing of human amyloid precursor protein in hippocampal neurons devoid of cathepsin D
    • Saftig P., Peters C., von Figura K., Craessaerts K., Van Leuven F., DeStrooper B. Amyloidogenic processing of human amyloid precursor protein in hippocampal neurons devoid of cathepsin D. J Biol. Chem. 271:1996;27241-27244.
    • (1996) J Biol. Chem. , vol.271 , pp. 27241-27244
    • Saftig, P.1    Peters, C.2    Von Figura, K.3    Craessaerts, K.4    Van Leuven, F.5    DeStrooper, B.6
  • 56
    • 0028895461 scopus 로고
    • The organization of the inner nuclear layer of the rabbit retina
    • Strettoi E., Masland R.H. The organization of the inner nuclear layer of the rabbit retina. J Neurosci. 15:1995;875-888.
    • (1995) J Neurosci. , vol.15 , pp. 875-888
    • Strettoi, E.1    Masland, R.H.2
  • 57
    • 0031762512 scopus 로고    scopus 로고
    • Growth factors prevent changes in Bcl-2 and Bax expression and neuronal apoptosis induced by nitric oxide
    • Tamatani M., Ogawa S., Nunez G., Tohyama M. Growth factors prevent changes in Bcl-2 and Bax expression and neuronal apoptosis induced by nitric oxide. Cell Death Differ. 5:1998;911-919.
    • (1998) Cell Death Differ. , vol.5 , pp. 911-919
    • Tamatani, M.1    Ogawa, S.2    Nunez, G.3    Tohyama, M.4
  • 58
    • 0023270166 scopus 로고
    • Neuronal ceroid lipofuscinosis. Ocular histopathologic and electron microscopic studies in the late infantile, juvenile, and adult forms. Graefes
    • Traboulsi E.I., Green W.R., Luckenbach M.W., de la Cruz Z.C. Neuronal ceroid lipofuscinosis. Ocular histopathologic and electron microscopic studies in the late infantile, juvenile, and adult forms. Graefes. Arch. Clin. Exp. Ophthalmol. 225:1987;391-402.
    • (1987) Arch. Clin. Exp. Ophthalmol. , vol.225 , pp. 391-402
    • Traboulsi, E.I.1    Green, W.R.2    Luckenbach, M.W.3    De la Cruz, Z.C.4
  • 59
    • 0031966320 scopus 로고    scopus 로고
    • Mechanisms of cell death in the inherited retinal degenerations
    • Travis G.H. Mechanisms of cell death in the inherited retinal degenerations. Am J. Hum. Genet. 62:1998;503-508.
    • (1998) Am J. Hum. Genet. , vol.62 , pp. 503-508
    • Travis, G.H.1
  • 60
    • 0034659833 scopus 로고    scopus 로고
    • A mutation in the ovine cathepsin D gene causes a congenital lysosomal storage disease with profound neurodegeneration
    • Tyynelä J., Sohar I., Sleat D.E., Gin R.M., Donnelly R.J., Baumann M., Haltia M., Lobel P. A mutation in the ovine cathepsin D gene causes a congenital lysosomal storage disease with profound neurodegeneration. EMBO J. 19:2000;2786-2792.
    • (2000) EMBO J. , vol.19 , pp. 2786-2792
    • Tyynelä, J.1    Sohar, I.2    Sleat, D.E.3    Gin, R.M.4    Donnelly, R.J.5    Baumann, M.6    Haltia, M.7    Lobel, P.8
  • 61
    • 0035890085 scopus 로고    scopus 로고
    • The expanding role of mitochondria in apoptosis
    • Wang X. The expanding role of mitochondria in apoptosis. Genes Dev. 15:2001;2922-2933.
    • (2001) Genes Dev. , vol.15 , pp. 2922-2933
    • Wang, X.1
  • 63
    • 0035964220 scopus 로고    scopus 로고
    • Pheno/genotypic correlations of neuronal ceroid lipofuscinoses
    • Wisniewski K.E. Pheno/genotypic correlations of neuronal ceroid lipofuscinoses. Neurology. 57:2001;576-581.
    • (2001) Neurology , vol.57 , pp. 576-581
    • Wisniewski, K.E.1
  • 64
    • 0018830636 scopus 로고
    • Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation
    • Wyllie A.H. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature. 284:1980;555-556.
    • (1980) Nature , vol.284 , pp. 555-556
    • Wyllie, A.H.1
  • 65
    • 0025335995 scopus 로고
    • Immunohistochemical localization of cathepsin D in ocular tissues. Invest
    • Yamada T., Hara S., Tamai M. Immunohistochemical localization of cathepsin D in ocular tissues. Invest. Ophthalmol. Vis. Sci. 31:1990;1217-1223.
    • (1990) Ophthalmol. Vis. Sci. , vol.31 , pp. 1217-1223
    • Yamada, T.1    Hara, S.2    Tamai, M.3
  • 66
    • 0021679078 scopus 로고
    • Cell death during differentiation of the retina in the mouse
    • Young R.W. Cell death during differentiation of the retina in the mouse. J Comp. Neurol. 229:1984;362-373.
    • (1984) J Comp. Neurol. , vol.229 , pp. 362-373
    • Young, R.W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.