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Volumn 10, Issue , 2004, Pages 964-972

Systemic rapamycin inhibits retinal and choroidal neovascularization in mice

Author keywords

[No Author keywords available]

Indexed keywords

BROMETHOL; PHOSPHATE BUFFERED SALINE; RAPAMYCIN; TROPICAMIDE; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2; FLT1 PROTEIN, MOUSE; FLTN PROTEIN, MOUSE; IMMUNOSUPPRESSIVE AGENT; PROTEIN; SCLEROPROTEIN; VASCULAR ENDOTHELIAL GROWTH FACTOR A, MOUSE; VASCULOTROPIN A;

EID: 25444435486     PISSN: 10900535     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (104)

References (44)
  • 2
    • 0021752680 scopus 로고
    • Age-related macular degeneration blindness due to neovascular maculopathy
    • Ferris FL 3rd, Fine SL, Hyman L. Age-related macular degeneration and blindness due to neovascular maculopathy. Arch Ophthalmol 1984; 102:1640-2.
    • (1984) Arch. Ophthalmol. , vol.102 , pp. 1640-1642
    • Ferris, F.L.1    Fine III, S.L.2    Hyman, L.3
  • 3
    • 0026409933 scopus 로고
    • Argon laser photocoagulation for neovascular maculopathy. Five-year results from randomized clinical trials
    • Macular Photocoagulation Study Group. Erratum in: Arch Ophthalmol 1992; 110:761
    • Argon laser photocoagulation for neovascular maculopathy. Five-year results from randomized clinical trials. Macular Photocoagulation Study Group. Arch Ophthalmol 1991; 109:1109-14. Erratum in: Arch Ophthalmol 1992; 110:761.
    • (1991) Arch. Ophthalmol. , vol.109 , pp. 1109-1114
  • 4
    • 0033520641 scopus 로고    scopus 로고
    • Histopathology of age-related macular degeneration
    • Green WR. Histopathology of age-related macular degeneration. Mol Vis 1999; 5:27 .
    • (1999) Mol. Vis. , vol.5 , pp. 27
    • Green, W.R.1
  • 7
    • 0028815295 scopus 로고
    • Vascular endothelial growth factor/vascular permeability factor expression in a mouse model of retinal neovascularization
    • Pierce EA, Avery RL, Foley ED, Aiello LP, Smith LE. Vascular endothelial growth factor/vascular permeability factor expression in a mouse model of retinal neovascularization. Proc Natl Acad Sci U S A 1995; 92:905-9.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 905-909
    • Pierce, E.A.1    Avery, R.L.2    Foley, E.D.3    Aiello, L.P.4    Smith, L.E.5
  • 8
    • 0028786651 scopus 로고
    • Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins
    • Aiello LP, Pierce EA, Foley ED, Takagi H, Chen H, Riddle L, Ferrara N, King GL, Smith LE. Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins. Proc Natl Acad Sci U S A 1995; 92:10457-61.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 10457-10461
    • Aiello, L.P.1    Pierce, E.A.2    Foley, E.D.3    Takagi, H.4    Chen, H.5    Riddle, L.6    Ferrara, N.7    King, G.L.8    Smith, L.E.9
  • 9
  • 10
    • 0345701306 scopus 로고    scopus 로고
    • A peptide encoded by exon 6 of VEGF (EG3306) inhibits VEGF-induced angiogenesis in vitro ischaemic retinal neovascularisation in vivo
    • Bainbridge JW, Jia H, Bagherzadeh A, Selwood D, Ali RR, Zachary I. A peptide encoded by exon 6 of VEGF (EG3306) inhibits VEGF-induced angiogenesis in vitro and ischaemic retinal neovascularisation in vivo. Biochem Biophys Res Commun 2003; 302:793-9.
    • (2003) Biochem. Biophys. Res. Commun. , vol.302 , pp. 793-799
    • Bainbridge, J.W.1    Jia, H.2    Bagherzadeh, A.3    Selwood, D.4    Ali, R.R.5    Zachary, I.6
  • 14
    • 0019963926 scopus 로고
    • Subretinal neovascularization. Natural history of an experimental model
    • Ryan SJ. Subretinal neovascularization. Natural history of an experimental model. Arch Ophthalmol 1982; 100:1804-9.
    • (1982) Arch. Ophthalmol. , vol.100 , pp. 1804-1809
    • Ryan, S.J.1
  • 16
    • 0033882695 scopus 로고    scopus 로고
    • Overexpression of vascular endothelial growth factor (VEGF) in the retinal pigment epithelium leads to the development of choroidal neovascularization
    • Erratum in: Am J Pathol 2000; 157:1413
    • Spilsbury K, Garrett KL, Shen WY, Constable IJ, Rakoczy PE. Overexpression of vascular endothelial growth factor (VEGF) in the retinal pigment epithelium leads to the development of choroidal neovascularization. Am J Pathol 2000; 157:135-44. Erratum in: Am J Pathol 2000; 157:1413.
    • (2000) Am. J. Pathol. , vol.157 , pp. 135-144
    • Spilsbury, K.1    Garrett, K.L.2    Shen, W.Y.3    Constable, I.J.4    Rakoczy, P.E.5
  • 17
    • 0033771172 scopus 로고    scopus 로고
    • Choroidal neovascularization in the rat induced by adenovirus mediated expression of vascular endothelial growth factor
    • Baffi J, Byrnes G, Chan CC, Csaky KG. Choroidal neovascularization in the rat induced by adenovirus mediated expression of vascular endothelial growth factor. Invest Ophthalmol Vis Sci 2000; 41:3582-9.
    • (2000) Invest. Ophthalmol. Vis. Sci. , vol.41 , pp. 3582-3589
    • Baffi, J.1    Byrnes, G.2    Chan, C.C.3    Csaky, K.G.4
  • 20
    • 0032105481 scopus 로고    scopus 로고
    • Rapamune (RAPA rapamycin sirolimus): Mechanism of action immunosuppressive effect results from blockade of signal transduction inhibition of cell cycle progression
    • Sehgal SN. Rapamune (RAPA, rapamycin, sirolimus): mechanism of action immunosuppressive effect results from blockade of signal transduction and inhibition of cell cycle progression. Clin Biochem 1998; 31:335-40.
    • (1998) Clin. Biochem. , vol.31 , pp. 335-340
    • Sehgal, S.N.1
  • 21
    • 0036275356 scopus 로고    scopus 로고
    • Hypoxia enhances vascular cell proliferation angiogenesis in vitro via rapamycin (mTOR)-dependent signaling
    • Humar R, Kiefer FN, Berns H, Resink TJ, Battegay EJ. Hypoxia enhances vascular cell proliferation and angiogenesis in vitro via rapamycin (mTOR)-dependent signaling. FASEB J 2002; 16:771-80.
    • (2002) FASEB J. , vol.16 , pp. 771-780
    • Humar, R.1    Kiefer, F.N.2    Berns, H.3    Resink, T.J.4    Battegay, E.J.5
  • 23
    • 0030751493 scopus 로고    scopus 로고
    • Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1 but not Flk-1/KDR is up-regulated by hypoxia
    • Gerber HP, Condorelli F, Park J, Ferrara N. Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia. J Biol Chem 1997; 272:23659-67.
    • (1997) J. Biol. Chem. , vol.272 , pp. 23659-23667
    • Gerber, H.P.1    Condorelli, F.2    Park, J.3    Ferrara, N.4
  • 26
    • 0032818006 scopus 로고    scopus 로고
    • Constitutive expression of VEGF VEGFR-1 VEGFR-2 in normal eyes
    • Erratum in: Invest Ophthalmol Vis Sci 2000; 41:368
    • Kim I, Ryan AM, Rohan R, Amano S, Agular S, Miller JW, Adamis AP. Constitutive expression of VEGF, VEGFR-1, and VEGFR-2 in normal eyes. Invest Ophthalmol Vis Sci 1999; 40:2115-21. Erratum in: Invest Ophthalmol Vis Sci 2000; 41:368.
    • (1999) Invest. Ophthalmol. Vis. Sci. , vol.40 , pp. 2115-2121
    • Kim, I.1    Ryan, A.M.2    Rohan, R.3    Amano, S.4    Agular, S.5    Miller, J.W.6    Adamis, A.P.7
  • 30
    • 85047693011 scopus 로고    scopus 로고
    • Selective stimulation of VEGFR-1 prevents oxygen-induced retinal vascular degeneration in retinopathy of prematurity
    • Shih SC, Ju M, Liu N, Smith LE. Selective stimulation of VEGFR-1 prevents oxygen-induced retinal vascular degeneration in retinopathy of prematurity. J Clin Invest 2003; 112:50-7.
    • (2003) J. Clin. Invest. , vol.112 , pp. 50-57
    • Shih, S.C.1    Ju, M.2    Liu, N.3    Smith, L.E.4
  • 31
    • 0346734123 scopus 로고    scopus 로고
    • Transforming growth factor beta1 induction of vascular endothelial growth factor receptor 1: Mechanism of pericyte-induced vascular survival in vivo
    • Shih SC, Ju M, Liu N, Mo JR, Ney JJ, Smith LE. Transforming growth factor beta1 induction of vascular endothelial growth factor receptor 1: mechanism of pericyte-induced vascular survival in vivo. Proc Natl Acad Sci U S A 2003; 100:15859-64.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 15859-15864
    • Shih, S.C.1    Ju, M.2    Liu, N.3    Mo, J.R.4    Ney, J.J.5    Smith, L.E.6
  • 33
    • 0027421333 scopus 로고
    • Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor
    • Kendall RL, Thomas KA. Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor. Proc Natl Acad Sci U S A 1993; 90:10705-9.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10705-10709
    • Kendall, R.L.1    Thomas, K.A.2
  • 34
    • 0030582384 scopus 로고    scopus 로고
    • Identification of a natural soluble form of the vascular endothelial growth factor receptor FLT-1 its heterodimerization with KDR
    • Kendall RL, Wang G, Thomas KA. Identification of a natural soluble form of the vascular endothelial growth factor receptor, FLT-1, and its heterodimerization with KDR. Biochem Biophys Res Commun 1996; 226:324-8.
    • (1996) Biochem. Biophys. Res. Commun. , vol.226 , pp. 324-328
    • Kendall, R.L.1    Wang, G.2    Thomas, K.A.3
  • 36
    • 0036083592 scopus 로고    scopus 로고
    • Potential long-term inhibition of ocular neovascularisation by recombinant adeno-associated virus-mediated secretion gene therapy
    • Lai YK, Shen WY, Brankov M, Lai CM, Constable IJ, Rakoczy PE. Potential long-term inhibition of ocular neovascularisation by recombinant adeno-associated virus-mediated secretion gene therapy. Gene Ther 2002; 9:804-13.
    • (2002) Gene Ther. , vol.9 , pp. 804-813
    • Lai, Y.K.1    Shen, W.Y.2    Brankov, M.3    Lai, C.M.4    Constable, I.J.5    Rakoczy, P.E.6
  • 38
    • 0030844479 scopus 로고    scopus 로고
    • Transgenic mice with increased expression of vascular endothelial growth factor in the retina: A new model of intraretinal subretinal neovascularization
    • Okamoto N, Tobe T, Hackett SF, Ozaki H, Vinores MA, LaRochelle W, Zack DJ, Campochiaro PA. Transgenic mice with increased expression of vascular endothelial growth factor in the retina: a new model of intraretinal and subretinal neovascularization. Am J Pathol 1997; 151:281-91.
    • (1997) Am. J. Pathol. , vol.151 , pp. 281-291
    • Okamoto, N.1    Tobe, T.2    Hackett, S.F.3    Ozaki, H.4    Vinores, M.A.5    LaRochelle, W.6    Zack, D.J.7    Campochiaro, P.A.8
  • 40
    • 0037008770 scopus 로고    scopus 로고
    • Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway
    • Treins C, Giorgetti-Peraldi S, Murdaca J, Semenza GL, Van Obberghen E. Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway. J Biol Chem 2002; 277:27975-81.
    • (2002) J. Biol. Chem. , vol.277 , pp. 27975-27981
    • Treins, C.1    Giorgetti-Peraldi, S.2    Murdaca, J.3    Semenza, G.L.4    Van Obberghen, E.5
  • 43
    • 1042280986 scopus 로고    scopus 로고
    • An open-label randomized trial of the safety efficacy of sirolimus vs. azathioprine in living related renal allograft recipients receiving cyclosporine prednisone combination
    • Machado PG, Felipe CR, Hanzawa NM, Park SI, Garcia R, Alfieri F, Franco M, Silva HT Jr, Medina-Pestana JO. An open-label randomized trial of the safety and efficacy of sirolimus vs. azathioprine in living related renal allograft recipients receiving cyclosporine and prednisone combination. Clin Transplant 2004; 18:28-38.
    • (2004) Clin. Transplant. , vol.18 , pp. 28-38
    • Machado, P.G.1    Felipe, C.R.2    Hanzawa, N.M.3    Park, S.I.4    Garcia, R.5    Alfieri, F.6    Franco, M.7    Silva Jr., H.T.8    Medina-Pestana, J.O.9


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