Chloroquine enhances the cytotoxicity of topotecan by inhibiting autophagy in lung cancer cells

Chinese Journal of Cancer

Volumn 30, Issue 10, 2011, Pages 690-700

  Wang, Yao ^a,b   Peng, Rui Qing ^a   Li, Dan Dan ^a   Ding, Ya ^a   Wu, Xiao Qi ^a   Zeng, Yi Xin ^a   Zhu, Xiao Feng ^a   Zhang, Xiao Shi ^a  

^a SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^b ZHONGSHAN PEOPLE S HOSPITAL   (China)

Author keywords

Autophagy; Chemotherapy; Chloroquine; Lung cancer

Indexed keywords

CHLOROQUINE; PROTEIN BCL 2; TOPOTECAN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL; CELL CYCLE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG POTENTIATION; DRUG SAFETY; FLOW CYTOMETRY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LUNG CANCER; MEMBRANE PERMEABILITY; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RNA INTERFERENCE; SIDE POPULATION CELL;

APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; BCL-2-ASSOCIATED X PROTEIN; CELL LINE, TUMOR; CELL PROLIFERATION; CHLOROQUINE; DRUG SYNERGISM; HUMANS; LUNG NEOPLASMS; MEMBRANE PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; TOPOISOMERASE I INHIBITORS; TOPOTECAN;

EID: 80054764087     PISSN: 1000467X     EISSN: 1944446X     Source Type: Journal    
DOI: 10.5732/cjc.011.10056     Document Type: Article

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