ARPE-19 retinal pigment epithelial cells are highly resistant to oxidative stress and exercise strict control over their lysosomal redox-active iron

Autophagy

Volumn 5, Issue 4, 2009, Pages 494-501

  Kurz, Tino ^a,b   Karlsson, Markus ^a   Brunk, Ulf T ^a   Nilsson, Sven Erik ^a   Frennesson, Christina ^a  

^a LINKÖPING UNIVERSITY   (Sweden)

^b LINKÖPING UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Age related macular degeneration; Hydrogen peroxide; Iron; Iron chelation; Lipofuscin; Lysosomal stability; Lysosomes; Macrophage; Oxidative stress; Retinal pigment epithelial cells

Indexed keywords

HYDROGEN PEROXIDE; IRON; IRON BINDING PROTEIN; IRON CHELATING AGENT; LIPOFUSCIN; SALICYLALDEHYDE ISONICOTINOYL HYDRAZONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; AUTOPHAGY; CELL COMPARTMENTALIZATION; CELL DEATH; CELL DIVISION; CELL IMMORTALIZATION; CELL SURVIVAL; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DEGRADATION; HUMAN; HUMAN CELL; LIPOPHILICITY; LYSOSOME; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PIGMENT CELL; PIGMENT EPITHELIUM; RUPTURE;

EID: 66349110062     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.5.4.7961     Document Type: Article

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