α2 but not α1 AMP-activated protein kinase mediates oxidative stress-induced inhibition of retinal pigment epithelium cell phagocytosis of photoreceptor outer segments

Journal of Biological Chemistry

Volumn 283, Issue 11, 2008, Pages 6744-6751

  Qin, Suofu ^a   De Vries, Gerald W ^a  

^a ALLERGAN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDES; ANTIGEN-ANTIBODY REACTIONS; CELLS; CHEMICAL ACTIVATION; CHEMICAL REACTIONS; DRUG PRODUCTS; ENZYME ACTIVITY; IMMUNOLOGY; OXIDATIVE STRESS; PHOSPHORYLATION; PLASMA GUNS;

ACTIVATED PROTEIN KINASES; ADENOSINE KINASES; BARRIER FUNCTIONS; CARBOXAMIDE; CELL DYSFUNCTIONS; DIPYRIDAMOLE; GENETIC APPROACHES; KNOCK OUTS; MACULAR DEGENERATIONS; OUTER SEGMENTS; PHARMACOLOGICAL ACTIVATORS; RETINAL PIGMENT EPITHELIUMS; RISK FACTORS; RPE CELLS;

CYTOLOGY;

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; 5 IODOTUBERCIDIN; ACETYL COENZYME A CARBOXYLASE; AMP ACTIVATED PROTEIN KINASE ALPHA1; AMP ACTIVATED PROTEIN KINASE ALPHA2; DIPYRIDAMOLE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; UNCLASSIFIED DRUG; 5 AMINO 4 IMIDAZOLECARBOXAMIDE; AICA RIBONUCLEOTIDE; AMP ACTIVATED PROTEIN KINASES; AMP-ACTIVATED PROTEIN KINASES; DRUG DERIVATIVE; HYDROGEN PEROXIDE; MULTIENZYME COMPLEX; PROTEIN SERINE THREONINE KINASE; RIBONUCLEOTIDE; SERINE; THREONINE;

ARTICLE; CELL PROTECTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; ENZYME REGULATION; GENE TRANSLOCATION; HUMAN; HUMAN CELL; INHIBITION KINETICS; OXIDATIVE STRESS; PHAGOCYTOSIS; PIGMENT CELL; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN FUNCTION; BIOLOGICAL MODEL; CELL LINE; CHEMISTRY; CYTOLOGY; EPITHELIUM CELL; GENE EXPRESSION REGULATION; METABOLISM; PHOSPHORYLATION; PHOTORECEPTOR; PHYSIOLOGY;

AMINOIMIDAZOLE CARBOXAMIDE; CELL LINE; EPITHELIAL CELLS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; HYDROGEN PEROXIDE; MODELS, BIOLOGICAL; MULTIENZYME COMPLEXES; OXIDATIVE STRESS; PHAGOCYTOSIS; PHOSPHORYLATION; PHOTORECEPTORS; PIGMENT EPITHELIUM OF EYE; PROTEIN-SERINE-THREONINE KINASES; RIBONUCLEOTIDES; SERINE; THREONINE;

EID: 43749106701     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M708848200     Document Type: Article

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