Geldanamycin increases 4-hydroxynonenal (HNE)-induced cell death in human retinal pigment epithelial cells

Neuroscience Letters

Volumn 382, Issue 1-2, 2005, Pages 185-190

  Kaarniranta, Kai ^a,b   Ryhänen, Tuomas ^a   Karjalainen, Hannu M ^a   Lammi, Mikko J ^a   Suuronen, Tiina ^a   Huhtala, Anne ^c   Kontkanen, Matti ^d   Teräsvirta, Markku ^b   Uusitalo, Hannu ^a   Salminen, Antero ^a,b  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b KUOPIO UNIVERSITY HOSPITAL   (Finland)

^c UNIVERSITY OF TAMPERE MEDICAL SCHOOL   (Finland)

^d NORTH KARELIA CENTRAL HOSPITAL   (Finland)

Author keywords

Geldanamycin; Heat shock protein; Hydroxynonenal; Macular degeneration; Oxidative stress; Retinal pigment epithelial

Indexed keywords

4 HYDROXYNONENAL; CASPASE 3; GELDANAMYCIN; HEAT SHOCK PROTEIN 70; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN; TRANSCRIPTION FACTOR AP 1;

APOPTOSIS; ARTICLE; CELL DEATH; CELL PROTECTION; CONTROLLED STUDY; CYTOTOXICITY; DEFENSE MECHANISM; DNA BINDING; HUMAN; HUMAN CELL; METABOLIC ACTIVATION; NONHUMAN; OXIDATIVE STRESS; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA MACULA DEGENERATION;

ALDEHYDES; BENZOQUINONES; BLOTTING, WESTERN; CASPASE 3; CASPASES; CELL DEATH; CELL LINE; CYSTEINE PROTEINASE INHIBITORS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; HSP70 HEAT-SHOCK PROTEINS; HSP90 HEAT-SHOCK PROTEINS; HUMANS; LACTAMS, MACROCYCLIC; NF-KAPPA B; OXIDATIVE STRESS; PIGMENT EPITHELIUM OF EYE; QUINONES; TETRAZOLIUM SALTS; THIAZOLES; TRANSCRIPTION FACTOR AP-1;

EID: 21144434498     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2005.03.009     Document Type: Article

References (33)

1. K. Abravaya, M.P. Myers, S.P. Murphy, and R.I. Morimoto The human heat shock protein hsp70 interacts with HSF, the transcription factor that regulates heat shock gene expression Genes Dev. 6 1992 1153 1164
2. S. Beatty, H. Koh, M. Phil, D. Henson, and M. Boulton The role of oxidative stress in the pathogenesis of age-related macular degeneration Surv. Ophthalmol. 45 2000 115 134
3. I.J. Benjamin, and E.R. McMillan Stress (heat shock) proteins, molecular chaperones in cardiovascular biology and disease Circ. Res. 2 1998 117 132
4. J. Buchner Supervising the fold: functional principles of molecular chaperones FASEB J. 10 1989 10 19
5. F. Cajone, and A. Bernelli-Zazzera The action of 4-hydroxynonenal on heat shock gene expression in cultured hepatoma cells Free Radic. Biol. Med. 7 1989 189 194
6. S. Camandola, G. Poli, and M.P. Mattson The lipid peroxidation product 4-hydroxy-2,3-nonenal inhibits constitutive and inducible activity of nuclear factor kappa B in neurons Brain Res. Mol. Brain Res. 85 2000 53 60
7. S. Camandola, A. Scavazza, G. Leonarduzzi, F. Biasi, E. Chiarpotto, A. Azzi, and G. Poli Biogenic 4-hydroxy-2-nonenal activates transcription factor AP-1 but not NF-kappaB in cells of the macrophage lineage Biofactors 6 1997 173 179
8. R.J. Carmody, and T.G. Cotter Oxidative stress induces caspase-independent retinal apoptosis in vitro Cell Death Differ. 7 2000 282 291
9. M. Elo, R. Sironen, K. Kaarniranta, S. Auriola, H.J. Helminen, and M.J. Lammi Differential regulation of stress proteins by high hydrostatic pressure, heat shock and unbalanced calcium homeostasis in chondrocytic cells J. Cell Biochem. 79 2000 610 619
10. M.B. Hansen, S.E. Nielsen, and K. Berg Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell killing J. Immunol. Methods 119 1989 203 210
11. C. Jolly, and R.I. Morimoto Role of the heat shock response and molecular chaperones in oncogenesis and cell death J. Natl. Cancer Inst. 92 2000 1564 1572
12. K. Kaarniranta, M. Elo, R. Sironen, M.J. Lammi, M.B. Goldring, J.E. Eriksson, L. Sistonen, and H.J. Helminen Hsp70 accumulation in chondrocytic cells exposed to high continuous hydrostatic pressure coincides with mRNA stabilization rather than transcriptional activation Proc. Natl. Acad. Sci. USA 95 1998 2319 2324
13. K. Kaarniranta, C.I. Holmberg, H.J. Helminen, J.E. Eriksson, L. Sistonen, and M.J. Lammi Protein synthesis is required for stabilization of hsp70 mRNA upon exposure to both hydrostatic pressurization and elevated temperature FEBS Lett. 475 2000 283 286
14. K. Kaarniranta, N. Oksala, H.M. Karjalainen, T. Suuronen, L. Sistonen, H.J. Helminen, A. Salminen, and M.J. Lammi Neuronal cells show regulatory differences in the hsp70 gene response Brain Res. Mol. Brain Res. 101 2002 136 140
15. S. Lindquist, and E.A. Craig The heat shock response Annu. Rev. Genet. 22 1988 631 677
16. Y.M. Park, M.Y. Han, R.V. Blackburn, and Y.J. Lee Overexpression of HSP25 reduces the level of TNF alpha-induced oxidative DNA damage biomarker, 8-hydroxy-2′-deoxyguanosine, in L929 cells J. Cell Physiol. 174 1998 27 34
17. M. Parola, G. Bellomo, G. Robino, G. Barrera, and M.U. Dianzani 4-Hydroxynonenal as a biological signal: molecular basis and pathophysiological implications Antioxidants Redox Signal. 1 1999 255 284
18. M. Parola, G. Robino, F. Marra, M. Pinzani, G. Bellomo, G. Leonarduzzi, P. Chiarugi, S. Camandola, G. Poli, G. Waeg, P. Gentilini, and M.U. Dianzani HNE interacts directly with JNK isoforms in human hepatic stellate cells J. Clin. Invest. 102 1998 1942 1950
19. L. Pirkkala, P. Nykänen, and L. Sistonen Roles of the heat shock transcription factors in the regulation of the heat shock response and beyond FASEB J. 15 2001 1118 1131
20. S.A. Rabacchi, W.J. Friedman, M.L. Shelanski, and C.M. Troy Divergence of the apoptotic pathways induced by 4-hydroxynonenal and amyloid beta-protein Neurobiol. Aging 25 2004 1057 1066
21. J. Ruef, M. Moser, C. Bode, W. Kubler, and M.S. Runge 4-Hydroxynonenal induces apoptosis, NFkappaB-activation and formation of 8-isoprostane in vascular smooth muscle cells Basic Res. Cardiol. 96 2001 143 150
22. M. Schmidt, and P.M. Kloetzel Biogenesis of eukaryotic 20S proteasomes: the complex maturation pathway of a complex enzyme FASEB J. 11 1997 1235 1243
23. U. Siebenlist, G. Franzoso, and K. Brown Structure, regulation and function of NF-kappa B Annu. Rev. Cell. Biol. 10 1994 405 455
24. V. Solovyan, Z. Bezvenyuk, V. Huotari, T. Tapiola, T. Suuronen, and A. Salminen Distinct mode of apoptosis induced by genotoxic agent etoposide and serum withdrawal in neuroblastoma cells Brain Res. Mol. Brain Res. 62 1998 43 55
25. C. Soti, and P. Csermely Aging and molecular chaperones Exp. Gerontol. 38 2003 1037 1040
26. A.S. Sreedbar, K. Mihaly, B. Pato, T. Scnaider, A. Stetak, K. Kis-Petik, J. Fidy, T. Simonics, A. Maraz, and P. Csermely Hsp90 inhibition accelerates cell lysis. Anti-Hsp90 ribozyme reveals a complex mechanism of Hsp90 inhibitors involving both superoxide- and Hsp90-dependent events J. Biol. Chem. 278 2003 35231 35240
27. C.Y. Su, K.Y. Chong, K. Edelstein, S. Lille, R. Khardori, and C.C. Lai Constitutive hsp70 attenuates hydrogen peroxide-induced membrane lipid peroxidation Biochem. Biophys. Res. Commun. 265 1999 279 284
28. K. Tago, F. Tsukahara, M. Naruse, T. Yoshioka, and K. Takano Hsp90 inhibitors attenuate effect of dexamethasone on activation of NF-kappaB and AP-1 Life Sci. 74 2004 1981 1992
29. 2-, HNE-, or tBH-treated ARPE-cells Free Radic. Biol. Med. 33 2002 1419 1432
30. H. Yamamoto, Y. Yamamoto, K. Yamagami, M. Kume, S. Kimoto, S. Toyokuni, K. Uchida, M. Fukumoto, and Y. Yamaoka Heat-shock preconditioning reduces oxidative protein denaturation and ameliorates liver injury by carbontetrachloride in rats Res. Exp. Med. (Berl.) 199 2000 309 318
31. M. Yeo, H.K. Park, K.M. Lee, K.J. Lee, J.H. Kim, S.W. Cho, and K.B. Hahm Blockage of HSP 90 modulates Helicobacter pylori-induced IL-8 productions through the inactivation of transcriptional factors of AP-1 and NF-kappaB Biochem. Biophys. Res. Commun. 320 2004 816 824
32. R.W. Young Pathophysiology of age-related macular degeneration Surv. Ophthalmol. 31 1987 291 306
33. J. Zou, Y. Guo, T. Guettouche, D.F. Smith, and R. Voellmy Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress sensitive complex with HSF1 Cell 94 1998 471 480