-
1
-
-
77956571785
-
The importance of mitochondria in age-related and inherited eye disorders
-
Jarrett SG, Lewin AS, Boulton ME. The importance of mitochondria in age-related and inherited eye disorders. Ophthalmic Res. 2010; 44:179-190.
-
(2010)
Ophthalmic Res.
, vol.44
, pp. 179-190
-
-
Jarrett, S.G.1
Lewin, A.S.2
Boulton, M.E.3
-
3
-
-
33746406453
-
Mitochondrial alterations of retinal pigment epithelium in agerelated macular degeneration
-
Feher J, Kovacs I, Artico M, Cavallotti C, Papale A, Balacco Gabrieli C. Mitochondrial alterations of retinal pigment epithelium in agerelated macular degeneration. Neurobiol Aging. 2006;27:983-993.
-
(2006)
Neurobiol Aging.
, vol.27
, pp. 983-993
-
-
Feher, J.1
Kovacs, I.2
Artico, M.3
Cavallotti, C.4
Papale, A.5
Balacco Gabrieli, C.6
-
5
-
-
41949092130
-
Increased mitochondrial DNA damage and down-regulation of DNA repair enzymes in aged rodent retinal pigment epithelium and choroid
-
Wang AL, Lukas TJ, Yuan M, Neufeld AH. Increased mitochondrial DNA damage and down-regulation of DNA repair enzymes in aged rodent retinal pigment epithelium and choroid. Mol Vis. 2008;14: 644-651.
-
(2008)
Mol Vis.
, vol.14
, pp. 644-651
-
-
Wang, A.L.1
Lukas, T.J.2
Yuan, M.3
Neufeld, A.H.4
-
6
-
-
77956926306
-
Age-related increase in mitochondrial DNA damage and loss of DNA repair capacity in the neural retina
-
Wang AL, Lukas TJ, Yuan M, Neufeld AH. Age-related increase in mitochondrial DNA damage and loss of DNA repair capacity in the neural retina. Neurobiol Aging. 2010;31:2002-2010.
-
(2010)
Neurobiol Aging.
, vol.31
, pp. 2002-2010
-
-
Wang, A.L.1
Lukas, T.J.2
Yuan, M.3
Neufeld, A.H.4
-
7
-
-
66849130909
-
Mitochondrial DNA haplogroups associated with age-related macular degeneration
-
Udar N, Atilano SR, Memarzadeh M, et al. Mitochondrial DNA haplogroups associated with age-related macular degeneration. Invest Ophthalmol Vis Sci. 2009;50:2966-2974.
-
(2009)
Invest Ophthalmol Vis Sci.
, vol.50
, pp. 2966-2974
-
-
Udar, N.1
Atilano, S.R.2
Memarzadeh, M.3
et al4
-
8
-
-
77955911846
-
Characterization of retinal and blood mitochondrial DNA from age-related macular degeneration patients
-
Kenney MC, Atilano SR, Boyer D, et al. Characterization of retinal and blood mitochondrial DNA from age-related macular degeneration patients. Invest Ophthalmol Vis Sci. 2010;51:4289-4297.
-
(2010)
Invest Ophthalmol Vis Sci.
, vol.51
, pp. 4289-4297
-
-
Kenney, M.C.1
Atilano, S.R.2
Boyer, D.3
et al4
-
10
-
-
48249104648
-
Mitochondrial proteomics of the retinal pigment epithelium at progressive stages of age-related macular degeneration
-
Nordgaard CL, Karunadharma PP, Feng X, Olsen TW, Ferrington DA. Mitochondrial proteomics of the retinal pigment epithelium at progressive stages of age-related macular degeneration. Invest Ophthalmol Vis Sci. 2008;49:2848-2855.
-
(2008)
Invest Ophthalmol Vis Sci.
, vol.49
, pp. 2848-2855
-
-
Nordgaard, C.L.1
Karunadharma, P.P.2
Feng, X.3
Olsen, T.W.4
Ferrington, D.A.5
-
11
-
-
20444418659
-
Blue light induces mitochondrial DNA damage and free radical production in epithelial cells
-
Godley BF, Shamsi FA, Liang FQ, Jarrett SG, Davies S, Boulton M. Blue light induces mitochondrial DNA damage and free radical production in epithelial cells. J Biol Chem. 2005;280:21061-21066.
-
(2005)
J Biol Chem.
, vol.280
, pp. 21061-21066
-
-
Godley, B.F.1
Shamsi, F.A.2
Liang, F.Q.3
Jarrett, S.G.4
Davies, S.5
Boulton, M.6
-
12
-
-
0031032817
-
Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress
-
Yakes FM, Van Houten B. Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress. Proc Natl Acad Sci U S A. 1997; 94:514-519.
-
(1997)
Proc Natl Acad Sci U S A.
, vol.94
, pp. 514-519
-
-
Yakes, F.M.1
van Houten, B.2
-
13
-
-
0037375044
-
Oxidative stress-induced mitochondrial DNA damage in human retinal pigment epithelial cells: A possible mechanism for RPE aging and age-related macular degeneration
-
Liang FQ, Godley BF. Oxidative stress-induced mitochondrial DNA damage in human retinal pigment epithelial cells: a possible mechanism for RPE aging and age-related macular degeneration. Exp Eye Res. 2003;76:397-403.
-
(2003)
Exp Eye Res.
, vol.76
, pp. 397-403
-
-
Liang, F.Q.1
Godley, B.F.2
-
14
-
-
0037449724
-
Cell sorting experiments link persistent mitochondrial DNA damage with loss of mitochondrial membrane potential and apoptotic cell death
-
Santos JH, Hunakova L, Chen Y, Bortner C, Van Houten B. Cell sorting experiments link persistent mitochondrial DNA damage with loss of mitochondrial membrane potential and apoptotic cell death. J Biol Chem. 2003;278:1728-1734.
-
(2003)
J Biol Chem.
, vol.278
, pp. 1728-1734
-
-
Santos, J.H.1
Hunakova, L.2
Chen, Y.3
Bortner, C.4
van Houten, B.5
-
16
-
-
0035233241
-
Base excision repair in nuclear and mitochondrial DNA
-
Dianov GL, Souza-Pinto N, Nyaga SG, Thybo T, Stevnsner T, Bohr VA. Base excision repair in nuclear and mitochondrial DNA. Prog Nucl Acid Res Mol Biol. 2001;68:285-297.
-
(2001)
Prog Nucl Acid Res Mol Biol.
, vol.68
, pp. 285-297
-
-
Dianov, G.L.1
Souza-Pinto, N.2
Nyaga, S.G.3
Thybo, T.4
Stevnsner, T.5
Bohr, V.A.6
-
17
-
-
33744912521
-
Mitochondrial and nuclear DNA-repair capacity of various brain regions in mouse is altered in an age-dependent manner
-
Imam SZ, Karahalil B, Hogue BA, Souza-Pinto NC, Bohr VA. Mitochondrial and nuclear DNA-repair capacity of various brain regions in mouse is altered in an age-dependent manner. Neurobiol Aging. 2006;27:1129-1136.
-
(2006)
Neurobiol Aging.
, vol.27
, pp. 1129-1136
-
-
Imam, S.Z.1
Karahalil, B.2
Hogue, B.A.3
Souza-Pinto, N.C.4
Bohr, V.A.5
-
18
-
-
34247127167
-
Mitochondrial DNA repair: A critical player in the response of cells of the CNS to genotoxic insults
-
LeDoux SP, Druzhyna NM, Hollensworth SB, Harrison JF, Wilson GL. Mitochondrial DNA repair: a critical player in the response of cells of the CNS to genotoxic insults. Neuroscience. 2007;145: 1249-1259.
-
(2007)
Neuroscience.
, vol.145
, pp. 1249-1259
-
-
LeDoux, S.P.1
Druzhyna, N.M.2
Hollensworth, S.B.3
Harrison, J.F.4
Wilson, G.L.5
-
19
-
-
40649109989
-
Mitochondrial base excision repair of uracil and AP sites takes place by single-nucleotide insertion and long-patch DNA synthesis
-
Akbari M, Visnes T, Krokan HE, Otterlei M. Mitochondrial base excision repair of uracil and AP sites takes place by single-nucleotide insertion and long-patch DNA synthesis. DNA Repair (Amst). 2008;7:605-616.
-
(2008)
DNA Repair (Amst).
, vol.7
, pp. 605-616
-
-
Akbari, M.1
Visnes, T.2
Krokan, H.E.3
Otterlei, M.4
-
20
-
-
0036316413
-
Age-dependent decline of DNA repair activity for oxidative lesions in rat brain mitochondria
-
Chen D, Cao G, Hastings T, et al. Age-dependent decline of DNA repair activity for oxidative lesions in rat brain mitochondria. J Neurochem. 2002;81:1273-1284.
-
(2002)
J Neurochem.
, vol.81
, pp. 1273-1284
-
-
Chen, D.1
Cao, G.2
Hastings, T.3
et al4
-
21
-
-
0037726504
-
Decline of nuclear and mitochondrial oxidative base excision repair activity in late passage human diploid fibroblasts
-
Shen GP, Galick H, Inoue M, Wallace SS. Decline of nuclear and mitochondrial oxidative base excision repair activity in late passage human diploid fibroblasts. DNA Repair (Amst). 2003;2:673-693.
-
(2003)
DNA Repair (Amst).
, vol.2
, pp. 673-693
-
-
Shen, G.P.1
Galick, H.2
Inoue, M.3
Wallace, S.S.4
-
22
-
-
9444225094
-
The Minnesota Grading System of eye bank eyes for age-related macular degeneration
-
Olsen TW, Feng X. The Minnesota Grading System of eye bank eyes for age-related macular degeneration. Invest Ophthalmol Vis Sci. 2004;45:4484-4490.
-
(2004)
Invest Ophthalmol Vis Sci.
, vol.45
, pp. 4484-4490
-
-
Olsen, T.W.1
Feng, X.2
-
23
-
-
0029751074
-
Mitochondrial genome damage associated with cigarette smoking
-
Ballinger SW, Bouder TG, Davis GS, Judice SA, Nicklas JA, Albertini RJ. Mitochondrial genome damage associated with cigarette smoking. Cancer Res. 1996;56:5692-5697.
-
(1996)
Cancer Res.
, vol.56
, pp. 5692-5697
-
-
Ballinger, S.W.1
Bouder, T.G.2
Davis, G.S.3
Judice, S.A.4
Nicklas, J.A.5
Albertini, R.J.6
-
24
-
-
0033040503
-
Hydrogen peroxide causes significant mitochondrial DNA damage in human RPE cells
-
Ballinger SW, Van Houten B, Jin GF, Conklin CA, Godley BF. Hydrogen peroxide causes significant mitochondrial DNA damage in human RPE cells. Exp Eye Res. 1999;68:765-772.
-
(1999)
Exp Eye Res.
, vol.68
, pp. 765-772
-
-
Ballinger, S.W.1
van Houten, B.2
Jin, G.F.3
Conklin, C.A.4
Godley, B.F.5
-
25
-
-
34248647282
-
Rapid identification of unknown heteroplasmic mutations across the entire human mitochondrial genome with mismatch-specific Surveyor Nuclease
-
Bannwarth S, Procaccio V, Paquis-Flucklinger V. Rapid identification of unknown heteroplasmic mutations across the entire human mitochondrial genome with mismatch-specific Surveyor Nuclease. Nat Protoc. 2006;1:2037-2047.
-
(2006)
Nat Protoc.
, vol.1
, pp. 2037-2047
-
-
Bannwarth, S.1
Procaccio, V.2
Paquis-Flucklinger, V.3
-
26
-
-
33645635929
-
Pigment epithelium-derived factor inhibits angiogenesis via regulated intracellular proteolysis of vascular endothelial growth factor receptor 1
-
Cai J, Jiang WG, Grant MB, Boulton M. Pigment epithelium-derived factor inhibits angiogenesis via regulated intracellular proteolysis of vascular endothelial growth factor receptor 1. J Biol Chem. 2006;281:3604-3613.
-
(2006)
J Biol Chem.
, vol.281
, pp. 3604-3613
-
-
Cai, J.1
Jiang, W.G.2
Grant, M.B.3
Boulton, M.4
-
27
-
-
0035878869
-
Repair of 8-oxodeoxyguanosine lesions in mitochondrial dna depends on the oxoguanine DNA glycosylase (OGG1) gene and 8-oxoguanine accumulates in the mitochondrial DNA of OGG1-defective mice
-
de Souza-Pinto NC, Eide L, Hogue BA, et al. Repair of 8-oxodeoxyguanosine lesions in mitochondrial dna depends on the oxoguanine DNA glycosylase (OGG1) gene and 8-oxoguanine accumulates in the mitochondrial DNA of OGG1-defective mice. Cancer Res. 2001;61:5378-5381.
-
(2001)
Cancer Res.
, vol.61
, pp. 5378-5381
-
-
de Souza-Pinto, N.C.1
Eide, L.2
Hogue, B.A.3
et al4
-
28
-
-
0035869159
-
Inactivation of Saccharomyces cerevisiae OGG1 DNA repair gene leads to an increased frequency of mitochondrial mutants
-
Singh KK, Sigala B, Sikder HA, Schwimmer C. Inactivation of Saccharomyces cerevisiae OGG1 DNA repair gene leads to an increased frequency of mitochondrial mutants. Nucleic Acids Res. 2001;29:1381-1388.
-
(2001)
Nucleic Acids Res.
, vol.29
, pp. 1381-1388
-
-
Singh, K.K.1
Sigala, B.2
Sikder, H.A.3
Schwimmer, C.4
-
29
-
-
33751103471
-
Age-related macular degeneration-emerging pathogenetic and therapeutic concepts
-
Gehrs KM, Anderson DH, Johnson LV, Hageman GS. Age-related macular degeneration-emerging pathogenetic and therapeutic concepts. Ann Med. 2006;38:450-471.
-
(2006)
Ann Med.
, vol.38
, pp. 450-471
-
-
Gehrs, K.M.1
Anderson, D.H.2
Johnson, L.V.3
Hageman, G.S.4
-
31
-
-
11144258543
-
Drusen proteome analysis: An approach to the etiology of age-related macular degeneration
-
Crabb JW, Miyagi M, Gu X, et al. Drusen proteome analysis: an approach to the etiology of age-related macular degeneration. Proc Natl Acad Sci U S A. 2002;99:14682-14687.
-
(2002)
Proc Natl Acad Sci U S A.
, vol.99
, pp. 14682-14687
-
-
Crabb, J.W.1
Miyagi, M.2
Gu, X.3
et al4
-
32
-
-
4644344743
-
Receptor for advanced glycation end products and age-related macular degeneration
-
Howes KA, Liu Y, Dunaief JL, et al. Receptor for advanced glycation end products and age-related macular degeneration. Invest Ophthalmol Vis Sci. 2004;45:3713-3720.
-
(2004)
Invest Ophthalmol Vis Sci.
, vol.45
, pp. 3713-3720
-
-
Howes, K.A.1
Liu, Y.2
Dunaief, J.L.3
et al4
-
33
-
-
33947383078
-
Changes in select redox proteins of the retinal pigment epithelium in age-related macular degeneration
-
Decanini A, Nordgaard CL, Feng X, Ferrington DA, Olsen TW. Changes in select redox proteins of the retinal pigment epithelium in age-related macular degeneration. Am J Ophthalmol. 2007;143: 607-615.
-
(2007)
Am J Ophthalmol.
, vol.143
, pp. 607-615
-
-
Decanini, A.1
Nordgaard, C.L.2
Feng, X.3
Ferrington, D.A.4
Olsen, T.W.5
-
34
-
-
0032992736
-
Antioxidant enzymes in the macular retinal pigment epithelium of eyes with neovascular age-related macular degeneration
-
Frank RN, Amin RH, Puklin JE. Antioxidant enzymes in the macular retinal pigment epithelium of eyes with neovascular age-related macular degeneration. Am J Ophthalmol. 1999;127: 694-709.
-
(1999)
Am J Ophthalmol.
, vol.127
, pp. 694-709
-
-
Frank, R.N.1
Amin, R.H.2
Puklin, J.E.3
-
35
-
-
33645401537
-
Proteomics of the retinal pigment epithelium reveals altered protein expression at progressive stages of age-related macular degeneration
-
Nordgaard CL, Berg KM, Kapphahn RJ, et al. Proteomics of the retinal pigment epithelium reveals altered protein expression at progressive stages of age-related macular degeneration. Invest Ophthalmol Vis Sci. 2006;47:815-822.
-
(2006)
Invest Ophthalmol Vis Sci.
, vol.47
, pp. 815-822
-
-
Nordgaard, C.L.1
Berg, K.M.2
Kapphahn, R.J.3
et al4
-
36
-
-
77449095740
-
Mitochondrial DNA damage induced by 7-ketocholesterol in human retinal pigment epithelial cells in vitro
-
Gramajo AL, Zacharias LC, Neekhra A, et al. Mitochondrial DNA damage induced by 7-ketocholesterol in human retinal pigment epithelial cells in vitro. Invest Ophthalmol Vis Sci. 51:1164-1170.
-
Invest Ophthalmol Vis Sci.
, vol.51
, pp. 1164-1170
-
-
Gramajo, A.L.1
Zacharias, L.C.2
Neekhra, A.3
-
37
-
-
61849093145
-
Mitochondrial function and redox control in the aging eye: Role of MsrA and other repair systems in cataract and macular degenerations
-
Brennan LA, Kantorow M. Mitochondrial function and redox control in the aging eye: role of MsrA and other repair systems in cataract and macular degenerations. Exp Eye Res. 2009;88:195-203.
-
(2009)
Exp Eye Res.
, vol.88
, pp. 195-203
-
-
Brennan, L.A.1
Kantorow, M.2
-
38
-
-
20444483650
-
Nuclear gene expression changes due to mitochondrial dysfunction in ARPE-19 cells: Implications for agerelated macular degeneration
-
Miceli MV, Jazwinski SM. Nuclear gene expression changes due to mitochondrial dysfunction in ARPE-19 cells: implications for agerelated macular degeneration. Invest Ophthalmol Vis Sci. 2005; 46:1765-1773.
-
(2005)
Invest Ophthalmol Vis Sci.
, vol.46
, pp. 1765-1773
-
-
Miceli, M.V.1
Jazwinski, S.M.2
-
40
-
-
29044445172
-
Oxidative stressinduced retinal damage up-regulates DNA polymerase gamma and 8-oxoguanine-DNA-glycosylase in photoreceptor synaptic mitochondria
-
Cortina MS, Gordon WC, Lukiw WJ, Bazan NG. Oxidative stressinduced retinal damage up-regulates DNA polymerase gamma and 8-oxoguanine-DNA-glycosylase in photoreceptor synaptic mitochondria. Exp Eye Res. 2005;81:742-750.
-
(2005)
Exp Eye Res.
, vol.81
, pp. 742-750
-
-
Cortina, M.S.1
Gordon, W.C.2
Lukiw, W.J.3
Bazan, N.G.4
-
41
-
-
0038458979
-
Targeting human 8-oxoguanine glycosylase to mitochondria of oligodendrocytes protects against menadione-induced oxidative stress
-
Druzhyna NM, Hollensworth SB, Kelley MR, Wilson GL, Ledoux SP. Targeting human 8-oxoguanine glycosylase to mitochondria of oligodendrocytes protects against menadione-induced oxidative stress. Glia. 2003;42:370-378.
-
(2003)
Glia.
, vol.42
, pp. 370-378
-
-
Druzhyna, N.M.1
Hollensworth, S.B.2
Kelley, M.R.3
Wilson, G.L.4
Ledoux, S.P.5
|