Morphogenesis of the retinal pigment epithelium: Toward understanding retinal degenerative diseases

Annals of the New York Academy of Sciences

Volumn 857, Issue , 1998, Pages 1-12

  Marmorstein, Alan D ^a   Finnemann, Silvia C ^a   Bonilha, Vera L ^a   Rodriguez Boulan, Enrique ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); INTEGRIN; MEMBRANE PROTEIN; NERVE CELL ADHESION MOLECULE;

CELL DIFFERENTIATION; CELL POLARITY; CELL SURVIVAL; CONFERENCE PAPER; EPITHELIUM CELL; GENE EXPRESSION; GENE THERAPY; MORPHOGENESIS; MORPHOLOGY; PHENOTYPE; PHOTORECEPTOR; PIGMENT EPITHELIUM; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RETINA DEGENERATION;

EID: 0031761418     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1998.tb10102.x     Document Type: Conference Paper

References (46)

1. FERRIS, F. L. 1983. Senile macular degeneration: Review of epidemiologic features. Am. J. Epidemiol. 118:132-151.
2. LIEBOWITZ, et al. 1980. The framingham eye study monograph: An ophthalmologic and epidemiologic study of cataract, glaucoma, diabetic retinopathy, macular degeneration, and visual acuity in a general population of 2631 adults, 1973-1975. Surv. Opthalmol. 24 (Suppl.): 335-610.
3. DRYJA, T. P. 1998. Gene-based approach to human gene-phenotypic correlations. Proc. Natl. Acad. Sci. 94(22): 12117-12121.
4. ALLIKMETS, R., N. SINGH, H. SUN, et al. 1997. A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Stargardt macular dystrophy. Nat. Genet. 15(3): 236-246.
5. WEBER, B. H., G. VOGT, R. C. PRUETT, H. STOHR & U. FELBOR. 1994. Mutations in the tissue inhibitor of metalloproteinases-3 (TIMP-3) in patients with Sorsby's Fundus Dystrophy. Nat. Genet. 8(4): 352-356.
6. GU, S. M., D. A. THOMPSON, C. R. SRIKUMARI, B. LORENZ, U. FINCKH, A. NICOLETTI, K. R. MURTHY, M. RATHMANN, G. KUMARAMANICKAVEL, M. J. DENTON & A. GAL. 1997. Mutations in RPE65 cause autosomal recessive childhood-onset severe retinal dystrophy. Nat. Genet. 17(2): 194-197.
7. MAW, M. A., B. KENNEDY, A. KNIGHT, R. BRIDGES, K. E. ROTH, E. J. MANI, J. K. MUKKADAN, D. NANCARROW, J. W. CRABB & M. J. DENTON. 1997. Mutation of the gene encoding cellular retinaldehyde-binding protein in autosomal recessive retinitis pigmentosa. Nat. Genet. 17(2): 198-200.
8. PETRUKHIN, K., M. J. KOISTI, B. BAKALL, W. LI, G. XIE, T. MARKNELL, O. SANDGREN, K. FORSMAN, G. HOLMGREN, S. ANDREASSON, M. VUJIC, A. A. B. BERGEN, V. MCGARTY-DUGAN, D. FIGUEROA, C. P. AUSTIN, M. L. METZKER, C. T. CASKEY & C. WADELIUS. 1998. Identification of the gene responsible for best macular dystrophy. Nat. Genet. 19: 214-247.
9. MULLEN, R. J. & M. M. LA VAIL. 1996. Inherited retinal dystrophy: Primary defect in pigment epithelium determined with rat chimeras. Science 192: 799-801.
10. RUIZ A, P. BRETT & D. BOK. 1996. TIMP-3 is expressed in the human retinal pigment epithelium. Biochem. Biophys. Res. Commun. 226(2): 467-474.
11. DELLA, N. G., P. A. CAMPOCHIARO & D. J. ZACK. 1996. Localization of TIMP-3 mRNA expression to the retinal igment epithelium. Invest. Opthalmol. Vis. Sci. 37(9): 1921-1924.
12. FELBOR, U., D. DOEPNER, U. SCHNEIDER, E. ZRENNER & B. H. WEBER. 1997. Evaluation of the gene encoding the tissue inhibitor of metalloproteinases-3 in various maculopathies. Invest. Ophthalmol. Vis. Sci. 38(6): 1054-1059.
13. DE LA PAZ, M. A., M. A. PERICAK-VANCE, F. LENNON, J. L. HAINES & J. M. SEDDON. 1997. Exclusion of TIMP3 as a candidate locus in age-related macular degeneration. Invest. Ophthalmol. Vis. Sci. 38(6): 1060-1065.
14. FORRESTER, J., A. DICK, P. MCMENAMIN & W. LEE. 1996. The Eye: Basic Sciences in Practice. Saunders. London.
15. OLNEY, J. W. 1968. An electron microscopic study of synapse formation, receptor outer segment development, and other aspects of developing mouse retina. Invest. Ophthalmol. 7: 250-268.
16. DOWLING, J. E. & I. R. GIBBONS. 1962. The fine structure of the pigment epithelium in the albino rat. J. Cell Biol. 14: 459-474.
17. MARMORSTEIN, A. D., Y. CHEN, V. L. BONILHA, S. C. FINNEMANN, K. G. CSAKY & E. RODRIGUEZ-BOULAN. 1998. Apical polarity of N-CAM and EMMPRIN in retinal pigment epithelium resulting from suppression of basolateral signal recognition. J. Cell Biol. 142 (3), in press.
18. BRAEKEVELT, C. R. & M. J. HOLLENBERG. 1970. Development of the retinal pigment epithelium, choriocapillaris, and Bruch's membrane in the albino rat. Exp. Eye Res. 9: 124-131.
19. ZINN, K. M. & M. F. MARMOR. 1979. The Retinal Pigment Epithelium. Harvard University Press. Cambridge.
20. KORTE, G. E. 1984. New ultrastructure of rat RPE cells: Basal intracytoplasmic tubules. Exp. Eye Res. 38(4): 399-409.
21. BAVIK, C. O., F. LEVY, U. HELLMAN, C. WERNSTEDT & U. ERIKSSON. 1993. The retinal pigment epithelial membrane receptor for plasma retinol-binding protein. Isolation and cDNA cloning of the 63-kDa protein. J. Biol. Chem. 268(27): 20540-20546.
22. HAMEL, C. P., E. TSILOU, B. A. PFEFFER, J. J. HOOKS, B. DETRICK & T. M. REDMOND. 1993. Molecular cloning and expression of RPE65, a novel retinal pigment epithelium-specific microsomal protein that is post-transcriptionally regulated in vitro. J. Biol. Chem. 268(21): 15751-15757.
23. MILLER, S., R. STEINBERG & B. OAKLEY. 1978. The electrogenic sodium pump of the frog retinal pigment epithelium. J. Membr. Biol. 44: 259-279.
24. BOK, D. 1982. Autoradiographic studies on the polarity of plasma membrane receptors in RPE cells. In In the Structure of the Eye, J. Hollyfield, Ed.: 247-256. Elsevier North-Holland. New York.
25. GALLEMORE, R. P., B. A. HUGHS & S. S. MILLER. 1997. Retinal pigment epithelial transport mechanisms and their contributions to the electroretinogram. Prog. Retinal Eye Res. 16: 509-566.
26. NABI, I. R., A. P. MATHEWS, L. COHEN-GOULD, D. GUNDERSEN & E. RODRIGUEZ-BOULAN. 1993. Immortalization of polarized rat retinal pigment epithelium. J. Cell Sci. 104: 37-49.
27. +-ATPase in the retinal pigmented epithelium from chicken embryo is polarized in vivo but not in primary cell culture. Exp. Eye Res. 51: 435-446.
28. MARMORSTEIN, A. D., V. L. BONILHA, S. CHIFLET, J. M. NEILL & E. RODRIGUEZ-BOULAN. 1996. The polarity of the plasma membrane protein RET-PE2 in the retinal pigment epithelium is developmentally regulated. J Cell Sci. 109: 3025-3034.
29. RIZZOLO, L. J. & S. ZHOU. 1995. The distribution of Na, K-ATPase and 5A11 antigen in apical microvilli of the retinal pigment epithelium is unrelated to alpha-spectrin. J. Cell Sci. 108(11): 3623-3633.
30. RIZZOLO, L. J. 1997. Polarity and the development of the outer blood-retinal barrier. Histol. Histopath. 12(4):1057-1067.
31. FINNEMANN, S. C, V. L. BONILHA, A. D. MARMORSTEIN & E. RODRIGUEZ-BOULAN. 1997. Phagocytosis of rod outer segments by retinal pigment epithelial cells requires avB5 integrin for binding but not internalization. Proc. Natl. Acad. Sci. USA 94: 12932-12937.
32. RIZZOLO, L. J. & M. HEIGES. 1991. The polarity of the retinal pigment epithelium is developmentally regulated. Exp. Eye Res. 53: 549-553.
33. RATTO, G., D. ROBINSON, B. YAN & P. MCNAUGHTON. 1991. Development of the light response in neonatal mammalian rods. Nature 351: 654-657.
34. OKAMI, T., A. YAMAMOTO, K. OMORI, T. TAKADA, M. UYAMA & Y. TASHIRO. 1990. Immunocytochemical localization of Na,K-ATPase in rat retinal pigment epithelial cells. J. Histochem. Cytochem. 38: 1267-1275.
35. WEIMBS, T., S. H. LOW, S. J. CHAPIN & K. E. MOSTOV. 1997. Apical targeting in polarized epithelial cells: There's more afloat than rafts. Trends Cell Biol. 7: 393-399.
36. KELLER, P. & K. SIMONS. 1997. Post-golgi biosynthetic trafficking. J. Cell Sci. 110: 3001-3009.
37. LE GALL, A., C. YEAMAN, A. MUESCH & E. RODRIGUEZ-BOULAN. 1995. Epithelial cell polarity: New perspectives. Sem. Nephrol. 15(4): 272-284.
38. BONILHA, V. L., A. D. MARMORSTEIN, L. COHEN-GOULD & E. RODRIGUEZ-BOULAN. 1997. Apical sorting of hemagluttinin by transcytosis in retinal pigment epithelium. J. Cell Sci. 110(15): 1717-1727.
39. GUNDERSEN, D., S. K. POWELL & E. RODRIGUEZ-BOULAN. 1993. Apical polarization of N-CAM in retinal pigment epithelium is dependent on contact with the neural retina. J. Cell Biol. 121: 335-343.
40. HUNT, R.C. & A. A. DAVIS. 1992. Release of iron by human retinal pigment epithelial cells. J. Cell. Physiol. 152:102-110.
41. BOK, D. 1993. The retinal pigment epithelium: A versatile partner in vision. J. Cell Sci. 17(Suppl.): 189-95.
42. MARMORSTEIN, A. D., C. ZURZOLO, A. LE BIVIC & E. RODRIGUEZ-BOULAN. 1998. Cell surface biotinylation techniques and determination of protein polarity. In Cell Biology: A Laboratory Handbook, 2nd ed., Vol. 4, J. E. Celis, Ed.: 341-350. Academic Press. New York.
43. FINNEMANN, S. C., A. D. MARMORSTEIN, J. M. NEILL & E. RODRIGUEZ-BOULAN. 1997. Identification of the retinal pigment epithelium protein RET-PE2 as CE-9/OX-47, a member of the immunoglobulin superfamily. Invest. Ophthalmol. Vis. Sci. 38(11): 2366-2374.
44. POWELL, S. K., B. A. CUNNINGHAM, G. M. EDELMAN & E. RODRIGUEZ-BOULAN. 1991. Transmembrane and GPI anchored forms of NCAM are targeted to opposite domains of a polarized epithelial cell. Nature 353: 76-77.
45. LE GALL, A. H., S. K. POWELL, C. A. YEAMAN & E. RODRIGUEZ-BOULAN. 1996. N-CAM expresses a tyrosine independent basolateral sorting signal. J. Biol. Chem. 272(7): 4559-4567.
46. CASANOVA, J.E., P. P. BREITFELD, S. A. ROSS & K. E. MOSTOV. 1990. Phosphorylation of the polymeric immunoglobulin receptor required for its efficient transcytosis. Science 248: 742-745.