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Volumn 37, Issue 2, 1996, Pages 384-391

Accumulation of mitochondrial DNA deletions in human retina during aging

Author keywords

aging; mitochondrial DNA; neural retina; polymerase chain reaction technique; retinal pigment epithelium

Indexed keywords

MITOCHONDRIAL DNA;

EID: 0030062175     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (74)

References (50)
  • 1
    • 0024580556 scopus 로고
    • Decline in skeletal muscle mitochondrial respiratory chain function: Possible factor of ageing
    • Trounce I, Byrne E, Mazurki S. Decline in skeletal muscle mitochondrial respiratory chain function: possible factor of ageing. Lancet. 1989;i:637-639.
    • (1989) Lancet , vol.1 , pp. 637-639
    • Trounce, I.1    Byrne, E.2    Mazurki, S.3
  • 3
    • 0027365959 scopus 로고
    • Influence of the energetic pattern of mitochondria in cell ageing
    • Corbisier P, Remacle J. Influence of the energetic pattern of mitochondria in cell ageing. Mech Age Development. 1993;71:47-58.
    • (1993) Mech Age Development , vol.71 , pp. 47-58
    • Corbisier, P.1    Remacle, J.2
  • 4
    • 0028574053 scopus 로고
    • Mitochondrial DNA sequence variation in human evolution and disease
    • Wallace DC. Mitochondrial DNA sequence variation in human evolution and disease. Proc Natl Acad Sci USA. 1994;91:8739-8746.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 8739-8746
    • Wallace, D.C.1
  • 5
    • 0027021442 scopus 로고
    • Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain
    • Soong NW, Hinton DR, Cortopassi G, Arnheim N. Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain. Nature Genet. 1992;2:318-323.
    • (1992) Nature Genet. , vol.2 , pp. 318-323
    • Soong, N.W.1    Hinton, D.R.2    Cortopassi, G.3    Arnheim, N.4
  • 6
    • 0027017232 scopus 로고
    • Mitochondrial DNA deletion in human brain: Regional variability and increase with advanced age
    • Corral-Debrinski M, Horton T, Lott MT, et al. Mitochondrial DNA deletion in human brain: Regional variability and increase with advanced age. Nature Genet. 1992;2:324-329.
    • (1992) Nature Genet. , vol.2 , pp. 324-329
    • Corral-Debrinski, M.1    Horton, T.2    Lott, M.T.3
  • 7
    • 0025674177 scopus 로고
    • Detection of a specific mitochondrial DNA deletion in tissues of older humans
    • Cortopassi GA, Arhnheim N. Detection of a specific mitochondrial DNA deletion in tissues of older humans. Nucl Acids Res. 1990;18:6927-6933.
    • (1990) Nucl Acids Res. , vol.18 , pp. 6927-6933
    • Cortopassi, G.A.1    Arhnheim, N.2
  • 8
    • 0025113789 scopus 로고
    • Increase of deleted mitochondrial DNA in the striatum in Parkinson's disease and senescence
    • Ikebe S, Tanka M, Ohno K, et al Increase of deleted mitochondrial DNA in the striatum in Parkinson's disease and senescence. Biochem Biophys Res Commun. 1990;170:1044-1048.
    • (1990) Biochem Biophys Res Commun. , vol.170 , pp. 1044-1048
    • Ikebe, S.1    Tanka, M.2    Ohno, K.3
  • 9
  • 10
    • 0026732706 scopus 로고
    • Pattern of accumulation of somatic deletion of mitochondrial DNA in aging human tissues
    • Cortopassi GA, Shibata D, Soong NW, Arnheim NA. Pattern of accumulation of somatic deletion of mitochondrial DNA in aging human tissues. Proc Natl Acad Sci USA. 1992;89:7370-7374.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 7370-7374
    • Cortopassi, G.A.1    Shibata, D.2    Soong, N.W.3    Arnheim, N.A.4
  • 11
    • 0028349234 scopus 로고
    • Differential accumulations of 4977 pb deletion in mitochondrial DNA of various tissues in human ageing
    • Lee HC, Pang CY, Pang HS, Wei YH. Differential accumulations of 4977 pb deletion in mitochondrial DNA of various tissues in human ageing. Biochim Biophys Acta. 1994;1226:37-43.
    • (1994) Biochim Biophys Acta , vol.1226 , pp. 37-43
    • Lee, H.C.1    Pang, C.Y.2    Pang, H.S.3    Wei, Y.H.4
  • 12
    • 0023944266 scopus 로고
    • Studies of sequence heterogeneity of mitochondrial DNA from rat and mouse tissues: Evidence for an increased frequency of deletion/additions with aging
    • Piko L, Hougham AJ, Bulpitt KJ. Studies of sequence heterogeneity of mitochondrial DNA from rat and mouse tissues: Evidence for an increased frequency of deletion/additions with aging. Mech Ageing Development. 1988;43:279-293.
    • (1988) Mech Ageing Development , vol.43 , pp. 279-293
    • Piko, L.1    Hougham, A.J.2    Bulpitt, K.J.3
  • 13
    • 0026712284 scopus 로고
    • Mitochondrial DNA copy number and mitochondrial DNA deletion in adult and senescent rats
    • Gadaleta MN, Lezza AMS, Milella F, Fracasso F, Cantatore P. Mitochondrial DNA copy number and mitochondrial DNA deletion in adult and senescent rats. Mutat Res. 1992;275:181-183.
    • (1992) Mutat Res. , vol.275 , pp. 181-183
    • Gadaleta, M.N.1    Lezza, A.M.S.2    Milella, F.3    Fracasso, F.4    Cantatore, P.5
  • 15
    • 0027971105 scopus 로고
    • Detection and quantification by competitive PCR of an age-associated increase in a 4.8-kb deletion in rat mitochondrial DNA
    • Edris W, Burgett B, Stine OC, Filburn CR. Detection and quantification by competitive PCR of an age-associated increase in a 4.8-kb deletion in rat mitochondrial DNA. Mutat Res. 1994;316:69-78.
    • (1994) Mutat Res. , vol.316 , pp. 69-78
    • Edris, W.1    Burgett, B.2    Stine, O.C.3    Filburn, C.R.4
  • 17
  • 18
    • 0027941299 scopus 로고
    • Human skin mitochondrial DNA deletions associated with light exposure
    • Pang CY, Lee HC, Yang JH, Wei YH. Human skin mitochondrial DNA deletions associated with light exposure. Arch Biochem Biophys. 1994;312:534-538.
    • (1994) Arch Biochem Biophys. , vol.312 , pp. 534-538
    • Pang, C.Y.1    Lee, H.C.2    Yang, J.H.3    Wei, Y.H.4
  • 19
    • 0015319592 scopus 로고
    • The biologic clock: The mitochondria?
    • Harman D. The biologic clock: The mitochondria? J Am Geriatr Soc. 1972;20:145-147.
    • (1972) J Am Geriatr Soc. , vol.20 , pp. 145-147
    • Harman, D.1
  • 20
    • 0025864512 scopus 로고
    • An integrated theory of aging as the result of mitochondrial DNA mutation in differentiated cells
    • Miquel J. An integrated theory of aging as the result of mitochondrial DNA mutation in differentiated cells. Arch Gerontol Geriatr. 1991;12:99-117.
    • (1991) Arch Gerontol Geriatr. , vol.12 , pp. 99-117
    • Miquel, J.1
  • 21
    • 0024541837 scopus 로고
    • Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases
    • Linnane AW, Marzuki S, Ozawa T, Tanaka M. Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases. Lancet. 1989; 3:642-645.
    • (1989) Lancet , vol.3 , pp. 642-645
    • Linnane, A.W.1    Marzuki, S.2    Ozawa, T.3    Tanaka, M.4
  • 22
    • 0026587335 scopus 로고
    • Mitochondrial genetics: A paradigm for ageing and degenerative disease?
    • Wallace DC. Mitochondrial genetics: A paradigm for ageing and degenerative disease? Science. 1992; 256:628-632.
    • (1992) Science , vol.256 , pp. 628-632
    • Wallace, D.C.1
  • 23
    • 0027527023 scopus 로고
    • Oxidative damage to mitochondrial DNA shows marked age-dependent increases in human brain
    • Mecocci P, MacGarvey U, Kaufman AE, et al. Oxidative damage to mitochondrial DNA shows marked age-dependent increases in human brain. Ann Neurol. 1993;34:609-616.
    • (1993) Ann Neurol. , vol.34 , pp. 609-616
    • Mecocci, P.1    MacGarvey, U.2    Kaufman, A.E.3
  • 24
    • 0027420737 scopus 로고
    • Quantification of oxidative DNA modification in mitochondria
    • Hegler J, Bittner D, Boiteux S, Epe B. Quantification of oxidative DNA modification in mitochondria. Carcinogenesis. 1993;14:2309-2312.
    • (1993) Carcinogenesis , vol.14 , pp. 2309-2312
    • Hegler, J.1    Bittner, D.2    Boiteux, S.3    Epe, B.4
  • 25
    • 0026074885 scopus 로고
    • Hypoxemia is associated with mitochondrial DNA damage and gene induction
    • Corral-Debrinski M, Stepien G, Shoffner JM, et al. Hypoxemia is associated with mitochondrial DNA damage and gene induction. JAMA. 1991;2:1812-1816.
    • (1991) JAMA , vol.2 , pp. 1812-1816
    • Corral-Debrinski, M.1    Stepien, G.2    Shoffner, J.M.3
  • 26
    • 0022918956 scopus 로고
    • The role of antioxydant in the retina and retinal pigment epithelium and nature of pro-oxydant induced damage
    • Handelman GJ, Dratz EA. The role of antioxydant in the retina and retinal pigment epithelium and nature of pro-oxydant induced damage. Adv Free Radical Biol Med. 1986;2:1-89.
    • (1986) Adv Free Radical Biol Med. , vol.2 , pp. 1-89
    • Handelman, G.J.1    Dratz, E.A.2
  • 27
    • 84994986408 scopus 로고
    • Radiation and the ageing eye
    • Marshall J. Radiation and the ageing eye. Ophthalmol Physiol Opt. 1985;5:241-263.
    • (1985) Ophthalmol Physiol Opt. , vol.5 , pp. 241-263
    • Marshall, J.1
  • 28
    • 0004175945 scopus 로고
    • Cellular features retinal accumulation, and prospects of modification of age pigments in mammals
    • Sohal RS, ed. Amsterdam: Elsevier/North Holland Biochemical Press
    • Brizee KR, Ordy JM. Cellular features retinal accumulation, and prospects of modification of age pigments in mammals. In: Sohal RS, ed. Age Pigments. Amsterdam: Elsevier/North Holland Biochemical Press; 1981:317-334.
    • (1981) Age Pigments , pp. 317-334
    • Brizee, K.R.1    Ordy, J.M.2
  • 29
    • 0024778870 scopus 로고
    • Vitamin E and A in RPE lipofuscin formation and implications for age-related macular degeneration
    • Eldred GE. Vitamin E and A in RPE lipofuscin formation and implications for age-related macular degeneration. Prog Clin Biol Res. 1989;314:113-129.
    • (1989) Prog Clin Biol Res. , vol.314 , pp. 113-129
    • Eldred, G.E.1
  • 30
    • 0017843940 scopus 로고
    • Lipofuscin and melanin of human retinal pigment epithelium : Fluorescence, cytochemical and ultrastructural studies
    • Feeney L. Lipofuscin and melanin of human retinal pigment epithelium : Fluorescence, cytochemical and ultrastructural studies. Invest Ophthalmol Vis Sci. 1978;17:583-600.
    • (1978) Invest Ophthalmol Vis Sci. , vol.17 , pp. 583-600
    • Feeney, L.1
  • 31
    • 0026502611 scopus 로고
    • Aging of the human retina, differential loss of neurons and retinal pigment epithelial cells
    • Gao H, Hollyfield JG. Aging of the human retina, differential loss of neurons and retinal pigment epithelial cells. Invest Ophthalmol Vis Sci. 1992;33:1-17.
    • (1992) Invest Ophthalmol Vis Sci. , vol.33 , pp. 1-17
    • Gao, H.1    Hollyfield, J.G.2
  • 32
    • 0019020390 scopus 로고
    • The Framingham eye study monograph on 2631 adults (1973-1977)
    • Leibowitz HM, Krueger DE, Maunder LR, et al. The Framingham eye study monograph on 2631 adults (1973-1977). Surv Ophthalmol. 1980;24:335-610.
    • (1980) Surv Ophthalmol. , vol.24 , pp. 335-610
    • Leibowitz, H.M.1    Krueger, D.E.2    Maunder, L.R.3
  • 33
    • 0026343685 scopus 로고
    • Ageing of the retinal pigment epithelium
    • Osborne S, Chader G, eds. New York: Pergamon Press
    • Boulton M. Ageing of the retinal pigment epithelium. In: Osborne S, Chader G, eds. Progress in Retinal Research. New York: Pergamon Press; 1991:125-151.
    • (1991) Progress in Retinal Research , pp. 125-151
    • Boulton, M.1
  • 34
    • 0025355882 scopus 로고
    • Analysis of cytokine mRNA and DNA: Deletion and quantification by competitive polymerase chain reaction
    • Gilliland G, Perrin S, Blanchard K, Bunn F. Analysis of cytokine mRNA and DNA: Deletion and quantification by competitive polymerase chain reaction. Proc Natl Acad Sci USA. 1990;87:2725-2729.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 2725-2729
    • Gilliland, G.1    Perrin, S.2    Blanchard, K.3    Bunn, F.4
  • 35
    • 0027327280 scopus 로고
    • Expression of deleted mtDNA differ between human heteroplasmic skin fibroblast and Epstein-Barr virus transformed lymphocyte cultures
    • Bourgeron T, Chrétien D, Rötig A, et al. Expression of deleted mtDNA differ between human heteroplasmic skin fibroblast and Epstein-Barr virus transformed lymphocyte cultures. J Biol Chem. 1993;268:19369-19376.
    • (1993) J Biol Chem. , vol.268 , pp. 19369-19376
    • Bourgeron, T.1    Chrétien, D.2    Rötig, A.3
  • 36
    • 0015239454 scopus 로고
    • The turnover of mitochondria in a variety of tissues of young adult and aged rats
    • Menzies RA, Gold PH. The turnover of mitochondria in a variety of tissues of young adult and aged rats. J Biol Chem. 1971;246:2425-2429.
    • (1971) J Biol Chem. , vol.246 , pp. 2425-2429
    • Menzies, R.A.1    Gold, P.H.2
  • 37
    • 0025309791 scopus 로고
    • Mitochondrial mutations may increase oxidative stress: Implications for carcinogenesis and aging?
    • Brandy B, Davidson AJ. Mitochondrial mutations may increase oxidative stress: Implications for carcinogenesis and aging? Free Rad Biol Med. 1990;8:523-539.
    • (1990) Free Rad Biol Med. , vol.8 , pp. 523-539
    • Brandy, B.1    Davidson, A.J.2
  • 38
    • 0028291637 scopus 로고
    • The influences of age, retinal topography and gender on retinal degeneration in Fischer 344 rat
    • DiLoreto D, Cox C, Grover DC, et al. The influences of age, retinal topography and gender on retinal degeneration in Fischer 344 rat. Brain Res. 1994; 647:181-191.
    • (1994) Brain Res. , vol.647 , pp. 181-191
    • DiLoreto, D.1    Cox, C.2    Grover, D.C.3
  • 39
    • 0028081941 scopus 로고
    • Regional variation and age-related changes of lyzosomal enzymes in human retinal pigmented epithelium
    • Boulton M, Moriarty P, Jarvis-Evans J, Marcynuick B. Regional variation and age-related changes of lyzosomal enzymes in human retinal pigmented epithelium Br J Ophthalmol. 1994;78:125-129.
    • (1994) Br J Ophthalmol. , vol.78 , pp. 125-129
    • Boulton, M.1    Moriarty, P.2    Jarvis-Evans, J.3    Marcynuick, B.4
  • 40
    • 0017897377 scopus 로고
    • The topography and age relationship of lipofuscin accumulation in the retinal pigment epithelium
    • Wing GL, Blanchard GC, Weiter JJ. The topography and age relationship of lipofuscin accumulation in the retinal pigment epithelium. Invest Ophthalmol Vis Sci. 1978;17:601-607.
    • (1978) Invest Ophthalmol Vis Sci. , vol.17 , pp. 601-607
    • Wing, G.L.1    Blanchard, G.C.2    Weiter, J.J.3
  • 41
    • 0022585542 scopus 로고
    • Retinal pigment epithelial lipofuscin and melanin and choidal melanin in human eyes
    • Weiter JJ, Delorri FC, Wing GI, Fitch KA. Retinal pigment epithelial lipofuscin and melanin and choidal melanin in human eyes. Invest Ophthalmol Vis Sci. 1986;276:145-152.
    • (1986) Invest Ophthalmol Vis Sci. , vol.276 , pp. 145-152
    • Weiter, J.J.1    Delorri, F.C.2    Wing, G.I.3    Fitch, K.A.4
  • 42
    • 0024229143 scopus 로고
    • Topological variation in growth in cultured bovine retinal pigment epithelium
    • Burke J, Soref C. Topological variation in growth in cultured bovine retinal pigment epithelium Invest Ophthalmol Vis Sci. 1988;29:1784-1788.
    • (1988) Invest Ophthalmol Vis Sci. , vol.29 , pp. 1784-1788
    • Burke, J.1    Soref, C.2
  • 43
    • 0025885277 scopus 로고
    • Changes in distribution of mitochondria in the developing chick retina
    • Buono RJ, Sheffield JB. Changes in distribution of mitochondria in the developing chick retina. Exp Eye Res. 1991;53:187-198.
    • (1991) Exp Eye Res. , vol.53 , pp. 187-198
    • Buono, R.J.1    Sheffield, J.B.2
  • 44
    • 0021278073 scopus 로고
    • Variation in the frequency of complex forms of mitochoridrial DNA in different brain regions of senescent mice
    • Bulpitt KJ, Piko L. Variation in the frequency of complex forms of mitochoridrial DNA in different brain regions of senescent mice. Brain Res. 1984;300:41-48.
    • (1984) Brain Res. , vol.300 , pp. 41-48
    • Bulpitt, K.J.1    Piko, L.2
  • 45
    • 0028004453 scopus 로고
    • Mitochondrial DNA: Does more lead to less?
    • Poulton J, Holt IJ. Mitochondrial DNA: Does more lead to less? Nature Genet. 1994;8:313-315.
    • (1994) Nature Genet. , vol.8 , pp. 313-315
    • Poulton, J.1    Holt, I.J.2
  • 46
    • 0026671245 scopus 로고
    • Association of mitochondrial DNA damage with ageing and coronary atherosclerotic disease
    • Corral-Debrinski M, Shoffner JM, Lott MT, Wallace D. Association of mitochondrial DNA damage with ageing and coronary atherosclerotic disease. Mutat Res. 1992;275:169-180.
    • (1992) Mutat Res. , vol.275 , pp. 169-180
    • Corral-Debrinski, M.1    Shoffner, J.M.2    Lott, M.T.3    Wallace, D.4
  • 48
    • 0027933135 scopus 로고
    • Marked changes in mitochondrial DNA deletion levels in Alzheimer brains
    • Corral-Debrinski M, Horton T, Lott MT, et al. Marked changes in mitochondrial DNA deletion levels in Alzheimer brains. Genomics. 1994;23:471-476.
    • (1994) Genomics , vol.23 , pp. 471-476
    • Corral-Debrinski, M.1    Horton, T.2    Lott, M.T.3
  • 49
    • 0027215961 scopus 로고
    • A mitochondrial DNA deletion in normally aging and in Alzheimer brain tissue
    • Blanchard BJ, Park T, Fripp WJ, Lerman LS, Ingram VM. A mitochondrial DNA deletion in normally aging and in Alzheimer brain tissue. NeuroReport. 1993; 4:799-802.
    • (1993) NeuroReport , vol.4 , pp. 799-802
    • Blanchard, B.J.1    Park, T.2    Fripp, W.J.3    Lerman, L.S.4    Ingram, V.M.5
  • 50
    • 0029091194 scopus 로고
    • A mitochondrial DNA clone is associated with increased risk for Alzheimer disease
    • Hutchin T, Cortopassi G. A mitochondrial DNA clone is associated with increased risk for Alzheimer disease. Proc Natl Acad Sci USA. 1995;92:6892-6895.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 6892-6895
    • Hutchin, T.1    Cortopassi, G.2


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