-
3
-
-
0037174124
-
Proteome analysis of lipofuscin in human retinal pigment epithelial cells
-
Schutt F, Ueberle B, Schnolzer M, Holz FG, Kopitz J. Proteome analysis of lipofuscin in human retinal pigment epithelial cells. FEBS Lett 2002; 528:217-21.
-
(2002)
FEBS Lett
, vol.528
, pp. 217-221
-
-
Schutt, F.1
Ueberle, B.2
Schnolzer, M.3
Holz, F.G.4
Kopitz, J.5
-
4
-
-
0041342065
-
Proteins modified by malondialdehyde, 4-hydroxynonenal, or advanced glycation end products in lipofuscin of human retinal pigment epithelium
-
Schutt F, Bergmann M, Holz FG, Kopitz J. Proteins modified by malondialdehyde, 4-hydroxynonenal, or advanced glycation end products in lipofuscin of human retinal pigment epithelium. Invest Ophthalmol Vis Sci 2003; 44:3663-8.
-
(2003)
Invest Ophthalmol Vis Sci
, vol.44
, pp. 3663-3668
-
-
Schutt, F.1
Bergmann, M.2
Holz, F.G.3
Kopitz, J.4
-
5
-
-
0034703010
-
The biosynthesis of A2E, a fluorophore of aging retina, involves the formation of the precursor, A2-PE, in the photoreceptor outer segment membrane
-
Liu J, Itagaki Y, Ben-Shabat S, Nakanishi K, Sparrow JR. The biosynthesis of A2E, a fluorophore of aging retina, involves the formation of the precursor, A2-PE, in the photoreceptor outer segment membrane. J Biol Chem 2000; 275:29354-60.
-
(2000)
J Biol Chem
, vol.275
, pp. 29354-29360
-
-
Liu, J.1
Itagaki, Y.2
Ben-Shabat, S.3
Nakanishi, K.4
Sparrow, J.R.5
-
6
-
-
0032438193
-
Isolation and one-step preparation of A2E and iso-A2E, fluorophores from human retinal pigment epithelium
-
Parish CA, Hashimoto M, Nakanishi K, Dillon J, Sparrow J. Isolation and one-step preparation of A2E and iso-A2E, fluorophores from human retinal pigment epithelium. Proc Natl Acad Sci U S A 1998; 95:14609-13.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 14609-14613
-
-
Parish, C.A.1
Hashimoto, M.2
Nakanishi, K.3
Dillon, J.4
Sparrow, J.5
-
7
-
-
20244373585
-
Isolation of intact lysosomes from human RPE cells and effects of A2-E on the integrity of the lysosomal and other cellular membranes
-
Schutt F, Bergmann M, Holz FG, Kopitz J. Isolation of intact lysosomes from human RPE cells and effects of A2-E on the integrity of the lysosomal and other cellular membranes. Graefes Arch Clin Exp Ophthalmol 2002; 240:983-8.
-
(2002)
Graefes Arch Clin Exp Ophthalmol
, vol.240
, pp. 983-988
-
-
Schutt, F.1
Bergmann, M.2
Holz, F.G.3
Kopitz, J.4
-
8
-
-
0036932123
-
Detergent-like effects of the lipofuscin retinoid component A2-E in retinal pigment epithelial cells
-
Schutt F, Bergmann M, Kopitz J, Holz FG. [Detergent-like effects of the lipofuscin retinoid component A2-E in retinal pigment epithelial cells]. Ophthalmologe 2002; 99:861-5.
-
(2002)
Ophthalmologe
, vol.99
, pp. 861-865
-
-
Schutt, F.1
Bergmann, M.2
Kopitz, J.3
Holz, F.G.4
-
9
-
-
0034671726
-
Age-related macular degeneration. The lipofusion component N-retinyl-N-retinylidene ethanolamine detaches proapoptotic proteins from mitochondria and induces apoptosis in mammalian retinal pigment epithelial cells
-
Suter M, Reme C, Grimm C, Wenzel A, Jaattela M, Esser P, Kociok N, Leist M, Richter C. Age-related macular degeneration. The lipofusion component N-retinyl-N-retinylidene ethanolamine detaches proapoptotic proteins from mitochondria and induces apoptosis in mammalian retinal pigment epithelial cells. J Biol Chem 2000; 275:39625-30.
-
(2000)
J Biol Chem
, vol.275
, pp. 39625-39630
-
-
Suter, M.1
Reme, C.2
Grimm, C.3
Wenzel, A.4
Jaattela, M.5
Esser, P.6
Kociok, N.7
Leist, M.8
Richter, C.9
-
10
-
-
0033017053
-
Inhibition of lysosomal degradative functions in RPE cells by a retinoid component of lipofuscin
-
Holz FG, Schutt F, Kopitz J, Eldred GE, Kruse FE, Volcker HE, Cantz M. Inhibition of lysosomal degradative functions in RPE cells by a retinoid component of lipofuscin. Invest Ophthalmol Vis Sci 1999; 40:737-43.
-
(1999)
Invest Ophthalmol Vis Sci
, vol.40
, pp. 737-743
-
-
Holz, F.G.1
Schutt, F.2
Kopitz, J.3
Eldred, G.E.4
Kruse, F.E.5
Volcker, H.E.6
Cantz, M.7
-
11
-
-
0034086115
-
The lipofuscin fluorophore A2E mediates blue light-induced damage to retinal pigmented epithelial cells
-
Sparrow JR, Nakanishi K, Parish CA. The lipofuscin fluorophore A2E mediates blue light-induced damage to retinal pigmented epithelial cells. Invest Ophthalmol Vis Sci 2000; 41:1981-9.
-
(2000)
Invest Ophthalmol Vis Sci
, vol.41
, pp. 1981-1989
-
-
Sparrow, J.R.1
Nakanishi, K.2
Parish, C.A.3
-
12
-
-
0035040640
-
Blue light-induced apoptosis of A2E-containing RPE: Involvement of caspase-3 and protection by Bcl-2
-
Sparrow JR, Cai B. Blue light-induced apoptosis of A2E-containing RPE: involvement of caspase-3 and protection by Bcl-2. Invest Ophthalmol Vis Sci 2001; 42:1356-62.
-
(2001)
Invest Ophthalmol Vis Sci
, vol.42
, pp. 1356-1362
-
-
Sparrow, J.R.1
Cai, B.2
-
13
-
-
0037408428
-
DNA is a target of the photodynamic effects elicited in A2E-laden RPE by blue-light illumination
-
Sparrow JR, Zhou J, Cai B. DNA is a target of the photodynamic effects elicited in A2E-laden RPE by blue-light illumination. Invest Ophthalmol Vis Sci 2003; 44:2245-51.
-
(2003)
Invest Ophthalmol Vis Sci
, vol.44
, pp. 2245-2251
-
-
Sparrow, J.R.1
Zhou, J.2
Cai, B.3
-
14
-
-
0036205219
-
Involvement of oxidative mechanisms in bluelight-induced damage to A2E-laden RPE
-
Sparrow JR, Zhou J, Ben-Shabat S, Vollmer H, Itagaki Y, Nakanishi K. Involvement of oxidative mechanisms in bluelight-induced damage to A2E-laden RPE. Invest Ophthalmol Vis Sci 2002; 43:1222-7.
-
(2002)
Invest Ophthalmol Vis Sci
, vol.43
, pp. 1222-1227
-
-
Sparrow, J.R.1
Zhou, J.2
Ben-Shabat, S.3
Vollmer, H.4
Itagaki, Y.5
Nakanishi, K.6
-
15
-
-
0036495230
-
Formation of a nonaoxirane from A2E, a lipofuscin fluorophore related to macular degeneration, and evidence of singlet oxygen involvement
-
Ben-Shabat S, Itagaki Y, Jockusch S, Sparrow JR, Turro NJ, Nakanishi K. Formation of a nonaoxirane from A2E, a lipofuscin fluorophore related to macular degeneration, and evidence of singlet oxygen involvement. Angew Chem Int Ed Engl 2002; 41:814-7.
-
(2002)
Angew Chem Int Ed Engl
, vol.41
, pp. 814-817
-
-
Ben-Shabat, S.1
Itagaki, Y.2
Jockusch, S.3
Sparrow, J.R.4
Turro, N.J.5
Nakanishi, K.6
-
16
-
-
1942533542
-
Light exposure stimulates formation of A2E oxiranes in a mouse model of Stargardt's macular degeneration
-
Radu RA, Mata NL, Bagla A, Travis GH. Light exposure stimulates formation of A2E oxiranes in a mouse model of Stargardt's macular degeneration. Proc Natl Acad Sci U S A 2004; 101:5928-33.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 5928-5933
-
-
Radu, R.A.1
Mata, N.L.2
Bagla, A.3
Travis, G.H.4
-
17
-
-
4544360484
-
The photochemical oxidation of A2E results in the formation of a 5,8,5′,8′-bisfuranoid oxide
-
Dillon J, Wang Z, Avalle LB, Gaillard ER. The photochemical oxidation of A2E results in the formation of a 5,8,5′,8′-bisfuranoid oxide. Exp Eye Res 2004; 79:537-42.
-
(2004)
Exp Eye Res
, vol.79
, pp. 537-542
-
-
Dillon, J.1
Wang, Z.2
Avalle, L.B.3
Gaillard, E.R.4
-
18
-
-
0037705336
-
A2E-epoxides damage DNA in retinal pigment epithelial cells. Vitamin E and other antioxidants inhibit A2E-epoxide formation
-
Sparrow JR, Vollmer-Snarr HR, Zhou J, Jang YP, Jockusch S, Itagaki Y, Nakanishi K. A2E-epoxides damage DNA in retinal pigment epithelial cells. Vitamin E and other antioxidants inhibit A2E-epoxide formation. J Biol Chem 2003; 278:18207-13.
-
(2003)
J Biol Chem
, vol.278
, pp. 18207-18213
-
-
Sparrow, J.R.1
Vollmer-Snarr, H.R.2
Zhou, J.3
Jang, Y.P.4
Jockusch, S.5
Itagaki, Y.6
Nakanishi, K.7
-
19
-
-
0001670653
-
The role of A2E in prevention or enhancement of light damage in human retinal pigment epithelial cells
-
Roberts JE, Kukielczak BM, Hu DN, Miller DS, Bilski P, Sik RH, Motten AG, Chignell CF. The role of A2E in prevention or enhancement of light damage in human retinal pigment epithelial cells. Photochem Photobiol 2002; 75:184-90.
-
(2002)
Photochem Photobiol
, vol.75
, pp. 184-190
-
-
Roberts, J.E.1
Kukielczak, B.M.2
Hu, D.N.3
Miller, D.S.4
Bilski, P.5
Sik, R.H.6
Motten, A.G.7
Chignell, C.F.8
-
20
-
-
0035879852
-
Photocytotoxicity of lipofuscin in human retinal pigment epithelial cells
-
Davies S, Elliott MH, Floor E, Truscott TG, Zareba M, Sarna T, Shamsi FA, Boulton ME. Photocytotoxicity of lipofuscin in human retinal pigment epithelial cells. Free Radic Biol Med 2001; 31:256-65.
-
(2001)
Free Radic Biol Med
, vol.31
, pp. 256-265
-
-
Davies, S.1
Elliott, M.H.2
Floor, E.3
Truscott, T.G.4
Zareba, M.5
Sarna, T.6
Shamsi, F.A.7
Boulton, M.E.8
-
21
-
-
0000117096
-
Photodamage to human RPE cells by A2-E, a retinoid component of lipofuscin
-
Schutt F, Davies S, Kopitz J, Holz FG, Boulton ME. Photodamage to human RPE cells by A2-E, a retinoid component of lipofuscin. Invest Ophthalmol Vis Sci 2000; 41:2303-8.
-
(2000)
Invest Ophthalmol Vis Sci
, vol.41
, pp. 2303-2308
-
-
Schutt, F.1
Davies, S.2
Kopitz, J.3
Holz, F.G.4
Boulton, M.E.5
-
22
-
-
0004077654
-
Anatomy and histology of the eye and orbit in domestic animals
-
Springfield (IL): Charles C. Thomas
-
Prince JH, Diesem CD, Eglitis I, Ruskell GL. Anatomy and histology of the eye and orbit in domestic animals Springfield (IL): Charles C. Thomas; 1960.
-
(1960)
-
-
Prince, J.H.1
Diesem, C.D.2
Eglitis, I.3
Ruskell, G.L.4
-
23
-
-
0032710514
-
A2E, a lipofuscin fluorophore, in human retinal pigmented epithelial cells in culture
-
Sparrow JR, Parish CA, Hashimoto M, Nakanishi K. A2E, a lipofuscin fluorophore, in human retinal pigmented epithelial cells in culture. Invest Ophthalmol Vis Sci 1999; 40:2988-95.
-
(1999)
Invest Ophthalmol Vis Sci
, vol.40
, pp. 2988-2995
-
-
Sparrow, J.R.1
Parish, C.A.2
Hashimoto, M.3
Nakanishi, K.4
-
24
-
-
0029985705
-
Ocular age pigment "A2-E" An unprecedented pyridinium bisretinoid
-
Sakai N, Decatur J, Nakanishi K, Eldred GE. Ocular age pigment "A2-E" an unprecedented pyridinium bisretinoid. J Am Chem Soc 1996; 118:1559-60.
-
(1996)
J Am Chem Soc
, vol.118
, pp. 1559-1560
-
-
Sakai, N.1
Decatur, J.2
Nakanishi, K.3
Eldred, G.E.4
-
25
-
-
28844447280
-
Characterization of peroxy-A2E and furan-A2E photooxidation products and detection in human and mouse retinal pigment epithelial cell lipofuscin
-
Jang YP, Matsuda H, Itagaki Y, Nakanishi K, Sparrow JR. Characterization of peroxy-A2E and furan-A2E photooxidation products and detection in human and mouse retinal pigment epithelial cell lipofuscin. J Biol Chem 2005; 280:39732-9.
-
(2005)
J Biol Chem
, vol.280
, pp. 39732-39739
-
-
Jang, Y.P.1
Matsuda, H.2
Itagaki, Y.3
Nakanishi, K.4
Sparrow, J.R.5
-
26
-
-
0034814448
-
Reactions of 1,3-cyclohexadiene with singlet oxygen. A theoretical study
-
Sevin F, McKee ML. Reactions of 1,3-cyclohexadiene with singlet oxygen. A theoretical study. J Am Chem Soc 2001; 123:4591-600.
-
(2001)
J Am Chem Soc
, vol.123
, pp. 4591-4600
-
-
Sevin, F.1
McKee, M.L.2
-
27
-
-
1542346130
-
Hepatocellular bioactivation and cytotoxicity of the synthetic endoperoxide antimalarial arteflene
-
Maggs JL, Bishop LP, Batty KT, Dodd CC, Ilett KF, O'Neill PM, Edwards G, Kevin Park B. Hepatocellular bioactivation and cytotoxicity of the synthetic endoperoxide antimalarial arteflene. Chem Biol Interact 2004; 147:173-84.
-
(2004)
Chem Biol Interact
, vol.147
, pp. 173-184
-
-
Maggs, J.L.1
Bishop, L.P.2
Batty, K.T.3
Dodd, C.C.4
Ilett, K.F.5
O'Neill, P.M.6
Edwards, G.7
Kevin Park, B.8
-
28
-
-
0035088783
-
Isolation and structures of haterumadioxins A and B, cytotoxic endoperoxides from the Okinawan sponge Plakortis lita
-
Takada N, Watanabe M, Yamada A, Suenaga K, Yamada K, Ueda K, Uemura D. Isolation and structures of haterumadioxins A and B, cytotoxic endoperoxides from the Okinawan sponge Plakortis lita. J Nat Prod 2001; 64:356-9.
-
(2001)
J Nat Prod
, vol.64
, pp. 356-359
-
-
Takada, N.1
Watanabe, M.2
Yamada, A.3
Suenaga, K.4
Yamada, K.5
Ueda, K.6
Uemura, D.7
-
29
-
-
0033769372
-
A retinoid constituent of lipofuscin, A2-E, is a photosensitizer in human retinal pigment epithelial cells
-
Schutt F, Davies S, Kopitz J, Boulton M, Holz FG. [A retinoid constituent of lipofuscin, A2-E, is a photosensitizer in human retinal pigment epithelial cells]. Ophthalmologe 2000; 97:682-7.
-
(2000)
Ophthalmologe
, vol.97
, pp. 682-687
-
-
Schutt, F.1
Davies, S.2
Kopitz, J.3
Boulton, M.4
Holz, F.G.5
|