-
2
-
-
0040896044
-
An enzyme concerned with the formation of hydroxy acids from ketonic aldehydes
-
1:CAS:528:DyaC3sXhsFaktw%3D%3D
-
H. Dakin, H. Dudley, An enzyme concerned with the formation of hydroxy acids from ketonic aldehydes. J. Biol. Chem. 14, 423-431 (1913)
-
(1913)
J. Biol. Chem.
, vol.14
, pp. 423-431
-
-
Dakin, H.1
Dudley, H.2
-
3
-
-
0345528002
-
The occurrence of pyruvic acid and methylglyoxal in muscle metabolism
-
16744693 1:CAS:528:DyaA38XptV2m
-
E. Case, R. Cook, The occurrence of pyruvic acid and methylglyoxal in muscle metabolism. Biochem. J. 25(4), 1319-1335 (1931)
-
(1931)
Biochem. J.
, vol.25
, Issue.4
, pp. 1319-1335
-
-
Case, E.1
Cook, R.2
-
4
-
-
0347705885
-
A method of determination of some biologically important aldehydes and ketones, with special reference to pyruvic acid and methylglyoxal
-
16745003 1:CAS:528:DyaA3sXislWjtw%3D%3D
-
F. Clift, R.P. Cook, A method of determination of some biologically important aldehydes and ketones, with special reference to pyruvic acid and methylglyoxal. Biochem. J. 26(6), 1788-1799 (1932)
-
(1932)
Biochem. J.
, vol.26
, Issue.6
, pp. 1788-1799
-
-
Clift, F.1
Cook, R.P.2
-
5
-
-
0024536675
-
Glyoxalase activity in human red blood cells fractioned by age
-
2725076 1:CAS:528:DyaL1MXktVCqsLk%3D 10.1016/0047-6374(89)90026-2
-
A. McLellan, P.J. Thornalley, Glyoxalase activity in human red blood cells fractioned by age. Mech. Ageing Dev. 48(1), 63-71 (1989)
-
(1989)
Mech. Ageing Dev.
, vol.48
, Issue.1
, pp. 63-71
-
-
McLellan, A.1
Thornalley, P.J.2
-
6
-
-
0023778433
-
Modification of the glyoxalase system in human red blood cells by glucose in vitro
-
3196289 1:CAS:528:DyaL1cXlvVOrsrw%3D
-
P.J. Thornalley, Modification of the glyoxalase system in human red blood cells by glucose in vitro. Biochem. J. 254(3), 751-755 (1988)
-
(1988)
Biochem. J.
, vol.254
, Issue.3
, pp. 751-755
-
-
Thornalley, P.J.1
-
7
-
-
0024836625
-
Erythrocyte glyoxalase activity in genetically obese (ob/ob) and streptozotocin diabetic mice
-
2627763 1:CAS:528:DyaK3cXkvFGls70%3D
-
T. Atkins, P. Thornally, Erythrocyte glyoxalase activity in genetically obese (ob/ob) and streptozotocin diabetic mice. Diabetes Res. 11(3), 125-129 (1989)
-
(1989)
Diabetes Res.
, vol.11
, Issue.3
, pp. 125-129
-
-
Atkins, T.1
Thornally, P.2
-
8
-
-
0024458335
-
The human red blood cell glyoxalase system in diabetes mellitus
-
2776650 1:STN:280:DyaL1MznslGhtA%3D%3D 10.1016/0168-8227(89)90101-0
-
P.J. Thornalley, N. Hooper, P. Jennings, C. Florkowski, A. Jones, J. Lunec, A. Barnett, The human red blood cell glyoxalase system in diabetes mellitus. Diabetes Res. Clin. Pract. 7(2), 115-120 (1989)
-
(1989)
Diabetes Res. Clin. Pract.
, vol.7
, Issue.2
, pp. 115-120
-
-
Thornalley, P.J.1
Hooper, N.2
Jennings, P.3
Florkowski, C.4
Jones, A.5
Lunec, J.6
Barnett, A.7
-
9
-
-
0025298551
-
The glyoxalase system: New developments towards functional characterization of a metabolic pathway fundamental to biological life
-
2198020 1:CAS:528:DyaK3cXkslens74%3D
-
P.J. Thornalley, The glyoxalase system: new developments towards functional characterization of a metabolic pathway fundamental to biological life. Biochem. J. 269(1), 1-11 (1990)
-
(1990)
Biochem. J.
, vol.269
, Issue.1
, pp. 1-11
-
-
Thornalley, P.J.1
-
10
-
-
0028292698
-
Glyoxalase system in clinical diabetes mellitus and correlation with diabetic complications
-
1:STN:280:DyaK2czktVyrtQ%3D%3D
-
A. McLellan, P.J. Thornalley, J. Benn, P. Sonksen, Glyoxalase system in clinical diabetes mellitus and correlation with diabetic complications. Clin. Sci. (Lond) 87(1), 21-29 (1994)
-
(1994)
Clin. Sci. (Lond)
, vol.87
, Issue.1
, pp. 21-29
-
-
McLellan, A.1
Thornalley, P.J.2
Benn, J.3
Sonksen, P.4
-
11
-
-
0033525849
-
Increase in three alpha, beta-dicarbonyl compound levels in human uremic plasma: Specific in vivo determination of intermediates in advanced Maillard reaction
-
10066428 1:CAS:528:DyaK1MXhsVCksL0%3D 10.1006/bbrc.1999.0221
-
H. Odani, T. Shinzato, Y. Matsumoto, J. Usami, K. Maeda, Increase in three alpha, beta-dicarbonyl compound levels in human uremic plasma: specific in vivo determination of intermediates in advanced Maillard reaction. Biochem. Biophys. Res. Commun. 256(1), 89-93 (1999)
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.256
, Issue.1
, pp. 89-93
-
-
Odani, H.1
Shinzato, T.2
Matsumoto, Y.3
Usami, J.4
Maeda, K.5
-
12
-
-
20044376702
-
The pathobiology of diabetic complications: A unifying mechanism
-
15919781 1:CAS:528:DC%2BD2MXltVaisbk%3D 10.2337/diabetes.54.6.1615
-
M. Brownlee, The pathobiology of diabetic complications: a unifying mechanism. Diabetes 54(6), 1615-1625 (2005)
-
(2005)
Diabetes
, vol.54
, Issue.6
, pp. 1615-1625
-
-
Brownlee, M.1
-
13
-
-
33847078455
-
Apoptotic signaling in methylglyoxal-treated human osteoblasts involves oxidative stress, c-Jun N-terminal kinase, caspase-3 and p21-activated kanse-2
-
17131386 1:CAS:528:DC%2BD2sXhvFGlsrg%3D 10.1002/jcb.21114
-
W. Chan, H. Wu, N. Shao, Apoptotic signaling in methylglyoxal-treated human osteoblasts involves oxidative stress, c-Jun N-terminal kinase, caspase-3 and p21-activated kanse-2. J. Cell. Biochem. 100, 1056-1069 (2007)
-
(2007)
J. Cell. Biochem.
, vol.100
, pp. 1056-1069
-
-
Chan, W.1
Wu, H.2
Shao, N.3
-
14
-
-
53549106326
-
Plasma alpha-oxoaldehyde levels in diabetic and nondiabetic chronic kidney disease patients
-
18547947 1:CAS:528:DC%2BD1cXht1Slsb3L 10.1159/000139653
-
K. Nakayama, M. Nakayama, M. Iwabuchi, H. Terawaki, T. Sato, M. Kohno, S. Ito, Plasma alpha-oxoaldehyde levels in diabetic and nondiabetic chronic kidney disease patients. Am. J. Nephrol. 28(6), 871-878 (2008)
-
(2008)
Am. J. Nephrol.
, vol.28
, Issue.6
, pp. 871-878
-
-
Nakayama, K.1
Nakayama, M.2
Iwabuchi, M.3
Terawaki, H.4
Sato, T.5
Kohno, M.6
Ito, S.7
-
15
-
-
42549155621
-
Methylglyoxal: Its presence in beverages and potential scavengers
-
18448797 1:CAS:528:DC%2BD1cXmtFygtbY%3D 10.1196/annals.1433.027
-
D. Tan, Y. Wang, C. Lo, S. Sang, C. Ho, Methylglyoxal: its presence in beverages and potential scavengers. Ann. N. Y. Acad. Sci. 1126, 72-75 (2008)
-
(2008)
Ann. N. Y. Acad. Sci.
, vol.1126
, pp. 72-75
-
-
Tan, D.1
Wang, Y.2
Lo, C.3
Sang, S.4
Ho, C.5
-
16
-
-
59049094676
-
Fructose and carbonyl metabolites as endogenous toxins
-
19000661 1:CAS:528:DC%2BD1MXhsFOju74%3D 10.1016/j.cbi.2008.10.011
-
O. Lee, W. Bruce, Q. Dong, J. Bruce, R. Mehta, P. O'Brien, Fructose and carbonyl metabolites as endogenous toxins. Chem. Biol. Interact. 178(1-3), 332-339 (2009)
-
(2009)
Chem. Biol. Interact.
, vol.178
, Issue.1-3
, pp. 332-339
-
-
Lee, O.1
Bruce, W.2
Dong, Q.3
Bruce, J.4
Mehta, R.5
O'Brien, P.6
-
17
-
-
81055147172
-
Upregulation of aldolase B and overproduction of methylglyoxal in vascular tissues from rats with metabolic syndrome
-
21890532 1:CAS:528:DC%2BC3MXhsVOjsL3O 10.1093/cvr/cvr239
-
J. Liu, R. Wang, K. Desai, L. Wu, Upregulation of aldolase B and overproduction of methylglyoxal in vascular tissues from rats with metabolic syndrome. Cardiovasc. Res. 92(3), 494-503 (2011)
-
(2011)
Cardiovasc. Res.
, vol.92
, Issue.3
, pp. 494-503
-
-
Liu, J.1
Wang, R.2
Desai, K.3
Wu, L.4
-
18
-
-
1642313880
-
Involvement of SSAO-mediated deamination in adipose glucose transport and weight gain in obese diabetic KKAy mice
-
14656718 1:CAS:528:DC%2BD2cXjtlagur0%3D 10.1152/ajpendo.00272.2003
-
P. Yu, M. Wang, H. Fan, Y. Deng, D. Gubisne-Haberle, Involvement of SSAO-mediated deamination in adipose glucose transport and weight gain in obese diabetic KKAy mice. Am. J. Physiol. Endocrinol. Metab. 286(4), E634-E641 (2004)
-
(2004)
Am. J. Physiol. Endocrinol. Metab.
, vol.286
, Issue.4
-
-
Yu, P.1
Wang, M.2
Fan, H.3
Deng, Y.4
Gubisne-Haberle, D.5
-
19
-
-
0021175263
-
Solubilization and some properties of a semicarbazide-sensitive amine oxidase in brown adipose tissue of the rat
-
6477528 1:CAS:528:DyaL2cXlsVKlsro%3D
-
M. Barrand, B. Callingham, Solubilization and some properties of a semicarbazide-sensitive amine oxidase in brown adipose tissue of the rat. Biochem. J. 222, 467-475 (1984)
-
(1984)
Biochem. J.
, vol.222
, pp. 467-475
-
-
Barrand, M.1
Callingham, B.2
-
20
-
-
0033562836
-
Assessment of the deamination of aminoacetone, an endogenous substrate for semicarbazide-sensitive amine oxidase
-
10328770 1:CAS:528:DyaK1MXjtVekurs%3D 10.1006/abio.1999.4058
-
Y. Deng, P. Yu, Assessment of the deamination of aminoacetone, an endogenous substrate for semicarbazide-sensitive amine oxidase. Anal. Biochem. 270, 97-102 (1999)
-
(1999)
Anal. Biochem.
, vol.270
, pp. 97-102
-
-
Deng, Y.1
Yu, P.2
-
21
-
-
80052707653
-
Relationship of methylglyoxal-adduct biogenesis to LDL and triglyceride levels in diabetics
-
21839095 1:CAS:528:DC%2BC3MXhtFGgu7jM 10.1016/j.lfs.2011.07.021
-
Z. Turk, M. Cavlović-Naglić, N. Turk, Relationship of methylglyoxal-adduct biogenesis to LDL and triglyceride levels in diabetics. Life Sci. 89(13-14), 485-490 (2011)
-
(2011)
Life Sci.
, vol.89
, Issue.13-14
, pp. 485-490
-
-
Turk, Z.1
Cavlović-Naglić, M.2
Turk, N.3
-
22
-
-
22444446782
-
Assay of advanced glycation endproducts in selected beverages and food by liquid chromatography with tandem mass spectrometric detection
-
15945118 1:CAS:528:DC%2BD2MXos1CnsbY%3D 10.1002/mnfr.200500008
-
N. Ahmed, B. Mirshekar-Syahkal, L. Kennish, N. Karachalias, R. Babaei-Jadidi, P.J. Thornalley, Assay of advanced glycation endproducts in selected beverages and food by liquid chromatography with tandem mass spectrometric detection. Mol. Nutr. Food Res. 49(7), 691-699 (2005)
-
(2005)
Mol. Nutr. Food Res.
, vol.49
, Issue.7
, pp. 691-699
-
-
Ahmed, N.1
Mirshekar-Syahkal, B.2
Kennish, L.3
Karachalias, N.4
Babaei-Jadidi, R.5
Thornalley, P.J.6
-
23
-
-
70449449612
-
Hyperglycemia and glycation in diabetic complications
-
19489690 1:CAS:528:DC%2BD1MXhsVGlt7jE 10.1089/ars.2009.2484
-
A. Negre-Salvayre, R. Salvayre, N. Augé, R. Pamplona, M. Portero-Otín, Hyperglycemia and glycation in diabetic complications. Antioxid. Redox Signal. 11(12), 3071-3109 (2009)
-
(2009)
Antioxid. Redox Signal.
, vol.11
, Issue.12
, pp. 3071-3109
-
-
Negre-Salvayre, A.1
Salvayre, R.2
Augé, N.3
Pamplona, R.4
Portero-Otín, M.5
-
24
-
-
58149129133
-
Leptin decreases postprandially in people with type 2 diabetes, an effect reduced by the cooking method
-
18792885 1:CAS:528:DC%2BD1MXhsleht7s%3D 10.1055/s-0028-1083784
-
A. Stirban, M. Negrean, C. Götting, B. Stratmann, T. Gawlowski, M. Mueller-Roesel, K. Kleesiek, T. Koschinsky, D. Tschoepe, Leptin decreases postprandially in people with type 2 diabetes, an effect reduced by the cooking method. Horm. Metab. Res. 40(12), 896-900 (2008)
-
(2008)
Horm. Metab. Res.
, vol.40
, Issue.12
, pp. 896-900
-
-
Stirban, A.1
Negrean, M.2
Götting, C.3
Stratmann, B.4
Gawlowski, T.5
Mueller-Roesel, M.6
Kleesiek, K.7
Koschinsky, T.8
Tschoepe, D.9
-
25
-
-
72449202178
-
Profiling of alpha-dicarbonyl content of commercial honeys from different botanical origins: Identification of 3,4-dideoxyglucoson-3-ene (3,4-DGE) and related compounds
-
1:CAS:528:DC%2BD1MXhtlegurzI 10.1021/jf903341t
-
E. Marceau, V.A. Yaylayan, Profiling of alpha-dicarbonyl content of commercial honeys from different botanical origins: identification of 3,4-dideoxyglucoson-3-ene (3,4-DGE) and related compounds. Agric. Food Chem. 57(22), 10837-10844 (2009)
-
(2009)
Agric. Food Chem.
, vol.57
, Issue.22
, pp. 10837-10844
-
-
Marceau, E.1
Yaylayan, V.A.2
-
26
-
-
84862659880
-
Investigation of aqueous-phase photooxidation of glyoxal and methylglyoxal by aerosol chemical ionization mass spectrometry: Observation of hydroxyhydroperoxide formation
-
22296207 1:CAS:528:DC%2BC38XhsFylsro%3D 10.1021/jp211528d
-
R. Zhao, A. Lee, J.P. Abbatt, Investigation of aqueous-phase photooxidation of glyoxal and methylglyoxal by aerosol chemical ionization mass spectrometry: observation of hydroxyhydroperoxide formation. J. Phys. Chem. A. 116(24), 6253-6263 (2012)
-
(2012)
J. Phys. Chem. A.
, vol.116
, Issue.24
, pp. 6253-6263
-
-
Zhao, R.1
Lee, A.2
Abbatt, J.P.3
-
27
-
-
84863780734
-
Identification and quantification of six major α-dicarbonyl process contaminants in high-fructose corn syrup
-
22382856 1:CAS:528:DC%2BC38XjtFOmu7Y%3D 10.1007/s00216-012-5817-x
-
S. Gensberger, S. Mittelmaier, M. Glomb, M. Pischetsrieder, Identification and quantification of six major α-dicarbonyl process contaminants in high-fructose corn syrup. Anal. Bioanal. Chem. 403(10), 2923-2931 (2012)
-
(2012)
Anal. Bioanal. Chem.
, vol.403
, Issue.10
, pp. 2923-2931
-
-
Gensberger, S.1
Mittelmaier, S.2
Glomb, M.3
Pischetsrieder, M.4
-
28
-
-
84856004520
-
Formation of early and advanced Maillard reaction products correlates to the ripening of cheese
-
22224825 1:CAS:528:DC%2BC3MXhs1ehur3N 10.1021/jf204079f
-
R. Spanneberg, G. Salzwedel, M. Glomb, Formation of early and advanced Maillard reaction products correlates to the ripening of cheese. J. Agric. Food Chem. 60(2), 600-607 (2012)
-
(2012)
J. Agric. Food Chem.
, vol.60
, Issue.2
, pp. 600-607
-
-
Spanneberg, R.1
Salzwedel, G.2
Glomb, M.3
-
29
-
-
77955795700
-
Methylglyoxal content in drinking coffee as a cytotoxic factor
-
20722928 1:CAS:528:DC%2BC3cXhtFegtL3M 10.1111/j.1750-3841.2010.01658.x
-
J. Wang, T. Chang, Methylglyoxal content in drinking coffee as a cytotoxic factor. J. Food Sci. 75(6), H167-H171 (2010)
-
(2010)
J. Food Sci.
, vol.75
, Issue.6
-
-
Wang, J.1
Chang, T.2
-
30
-
-
33746920337
-
Advanced glycation end products: Sparking the development of diabetic vascular injury
-
16894049 1:CAS:528:DC%2BD28Xns1Snu70%3D 10.1161/CIRCULATIONAHA.106.621854
-
A. Goldin, J. Beckman, A. Schmidt, M. Creager, Advanced glycation end products: sparking the development of diabetic vascular injury. Circulation 114, 597-605 (2006)
-
(2006)
Circulation
, vol.114
, pp. 597-605
-
-
Goldin, A.1
Beckman, J.2
Schmidt, A.3
Creager, M.4
-
31
-
-
79955952814
-
Glyoxalase in ageing
-
21320620 1:CAS:528:DC%2BC3MXmtFSksr0%3D 10.1016/j.semcdb.2011.02.013
-
M. Xue, N. Rabbani, P. Thornalley, Glyoxalase in ageing. Semin. Cell Dev. Biol. 22(3), 293-301 (2011)
-
(2011)
Semin. Cell Dev. Biol.
, vol.22
, Issue.3
, pp. 293-301
-
-
Xue, M.1
Rabbani, N.2
Thornalley, P.3
-
32
-
-
79955945922
-
Glyoxalase in tumourigenesis and multidrug resistance
-
21315826 1:CAS:528:DC%2BC3MXmtFSksrg%3D 10.1016/j.semcdb.2011.02.006
-
P. Thornalley, N. Rabbani, Glyoxalase in tumourigenesis and multidrug resistance. Semin. Cell Dev. Biol. 22(3), 318-325 (2011)
-
(2011)
Semin. Cell Dev. Biol.
, vol.22
, Issue.3
, pp. 318-325
-
-
Thornalley, P.1
Rabbani, N.2
-
33
-
-
84858323567
-
A global perspective of the genetic basis for carbonyl stress resistance
-
1:CAS:528:DC%2BC38Xlt12jtrk%3D 10.1534/g3.111.000505
-
S. Hoon, M. Gebbia, M. Costanzo, R. Davis, G. Giaever, C. Nislow, A global perspective of the genetic basis for carbonyl stress resistance. G3 (Bethesda) 1(3), 219-231 (2011)
-
(2011)
G3 (Bethesda)
, vol.1
, Issue.3
, pp. 219-231
-
-
Hoon, S.1
Gebbia, M.2
Costanzo, M.3
Davis, R.4
Giaever, G.5
Nislow, C.6
-
34
-
-
82555188430
-
Determination of time-dependent accumulation of d-lactate in the streptozotocin-induced diabetic rat kidney by column-switching HPLC with fluorescence detection
-
21393073 1:CAS:528:DC%2BC3MXhtlKrtb7E 10.1016/j.jchromb.2011.02.015
-
M. Lin, H. Chen, T. Liao, T. Huang, C. Chen, J. Lee, Determination of time-dependent accumulation of d-lactate in the streptozotocin-induced diabetic rat kidney by column-switching HPLC with fluorescence detection. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 879(29), 3214-3219 (2011)
-
(2011)
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.
, vol.879
, Issue.29
, pp. 3214-3219
-
-
Lin, M.1
Chen, H.2
Liao, T.3
Huang, T.4
Chen, C.5
Lee, J.6
-
35
-
-
0028181753
-
Carbon sources for d-lactate formation in rat liver
-
8056777 1:CAS:528:DyaK2cXitFensLo%3D
-
Y. Kondoh, M. Kawase, M. Hirata, S. Ohmori, Carbon sources for d-lactate formation in rat liver. J. Biochem. 115(3), 590-595 (1994)
-
(1994)
J. Biochem.
, vol.115
, Issue.3
, pp. 590-595
-
-
Kondoh, Y.1
Kawase, M.2
Hirata, M.3
Ohmori, S.4
-
36
-
-
20544462655
-
D-lactate metabolism in starved Octopus ocellatus
-
15880764
-
T. Fujisawa, S. Akagi, M. Kawase, M. Yamamoto, S. Ohmori, d-lactate metabolism in starved Octopus ocellatus. J. Exp. Zool. A Comp. Exp. Biol. 303(6), 489-496 (2005)
-
(2005)
J. Exp. Zool. A Comp. Exp. Biol.
, vol.303
, Issue.6
, pp. 489-496
-
-
Fujisawa, T.1
Akagi, S.2
Kawase, M.3
Yamamoto, M.4
Ohmori, S.5
-
37
-
-
79955945923
-
Glyoxalase in diabetes, obesity and related disorders
-
21335095 1:CAS:528:DC%2BC3MXmtFSksrs%3D 10.1016/j.semcdb.2011.02.015
-
N. Rabbani, P.J. Thornalley, Glyoxalase in diabetes, obesity and related disorders. Semin. Cell Dev. Biol. 22(3), 309-317 (2011)
-
(2011)
Semin. Cell Dev. Biol.
, vol.22
, Issue.3
, pp. 309-317
-
-
Rabbani, N.1
Thornalley, P.J.2
-
38
-
-
84856719621
-
Long term running biphasically improves methylglyoxal-related metabolism, redox homeostasis and neurotrophic support within adult mouse brain cortex
-
22347470 1:CAS:528:DC%2BC38XivVWitb0%3D 10.1371/journal.pone.0031401
-
S. Falone, A. D'Alessandro, A. Mirabilio, G. Petruccelli, M. Cacchio, C. Di Ilio, S. Di Loreto, F. Amicarelli, Long term running biphasically improves methylglyoxal-related metabolism, redox homeostasis and neurotrophic support within adult mouse brain cortex. PLoS One 7(2), e31401 (2012)
-
(2012)
PLoS One
, vol.7
, Issue.2
, pp. 31401
-
-
Falone, S.1
D'Alessandro, A.2
Mirabilio, A.3
Petruccelli, G.4
Cacchio, M.5
Di Ilio, C.6
Di Loreto, S.7
Amicarelli, F.8
-
39
-
-
82855177408
-
Increased glyoxalase i levels inhibit accumulation of oxidative stress and an advanced glycation end product in mouse mesangial cells cultured in high glucose
-
22036650 1:CAS:528:DC%2BC3MXhsFOgurvN 10.1016/j.yexcr.2011.10.013
-
K. Kim, Y. Kim, D. Jung, J. Lee, J. Kim, Increased glyoxalase I levels inhibit accumulation of oxidative stress and an advanced glycation end product in mouse mesangial cells cultured in high glucose. Exp. Cell Res. 318(2), 152-159 (2012)
-
(2012)
Exp. Cell Res.
, vol.318
, Issue.2
, pp. 152-159
-
-
Kim, K.1
Kim, Y.2
Jung, D.3
Lee, J.4
Kim, J.5
-
40
-
-
84856729229
-
Protection against methylglyoxal-derived AGEs by regulation of glyoxalase 1 prevents retinal neuroglial and vasodegenerative pathology
-
22143324 1:CAS:528:DC%2BC38Xhsl2gtrg%3D 10.1007/s00125-011-2393-0
-
A. Berner, O. Brouwers, R. Pringle, I. Klaassen, L. Colhoun, C. McVicar, S. Brockbank, J. Curry, T. Miyata, M. Brownlee, R. Schlingemann, C. Schalkwijk, A.W. Stitt, Protection against methylglyoxal-derived AGEs by regulation of glyoxalase 1 prevents retinal neuroglial and vasodegenerative pathology. Diabetologia 55(3), 845-854 (2012)
-
(2012)
Diabetologia
, vol.55
, Issue.3
, pp. 845-854
-
-
Berner, A.1
Brouwers, O.2
Pringle, R.3
Klaassen, I.4
Colhoun, L.5
McVicar, C.6
Brockbank, S.7
Curry, J.8
Miyata, T.9
Brownlee, M.10
Schlingemann, R.11
Schalkwijk, C.12
Stitt, A.W.13
-
41
-
-
77949902248
-
The role of glyoxalase system in renal hypoxia
-
20204770 1:CAS:528:DC%2BC3cXhs1Wnu7bM 10.1007/978-1-4419-1241-1-6
-
R. Inagi, T. Kumagai, T. Fujita, M. Nangaku, The role of glyoxalase system in renal hypoxia. Adv. Exp. Med. Biol. 662, 49-55 (2010)
-
(2010)
Adv. Exp. Med. Biol.
, vol.662
, pp. 49-55
-
-
Inagi, R.1
Kumagai, T.2
Fujita, T.3
Nangaku, M.4
-
42
-
-
84857503169
-
Protection from diabetes-induced peripheral sensory neuropathy - A role for elevated glyoxalase I?
-
22201551 1:CAS:528:DC%2BC38XjsVWgsr8%3D 10.1016/j.expneurol.2011.12.015
-
M. Jack, J. Ryals, D. Wright, Protection from diabetes-induced peripheral sensory neuropathy - a role for elevated glyoxalase I? Exp. Neurol. 234(1), 62-69 (2012)
-
(2012)
Exp. Neurol.
, vol.234
, Issue.1
, pp. 62-69
-
-
Jack, M.1
Ryals, J.2
Wright, D.3
-
43
-
-
84860232014
-
Is diabetes an acquired disorder of reactive glucose metabolites and their intermediates?
-
22270223 1:CAS:528:DC%2BC38Xjs1SjsLo%3D 10.1007/s00125-012-2452-1
-
T. Fleming, J. Cuny, G. Nawroth, Z. Djuric, P. Humpert, M. Zeier, A. Bierhaus, P. Nawroth, Is diabetes an acquired disorder of reactive glucose metabolites and their intermediates? Diabetologia 55(4), 1151-1155 (2012)
-
(2012)
Diabetologia
, vol.55
, Issue.4
, pp. 1151-1155
-
-
Fleming, T.1
Cuny, J.2
Nawroth, G.3
Djuric, Z.4
Humpert, P.5
Zeier, M.6
Bierhaus, A.7
Nawroth, P.8
-
44
-
-
59749094860
-
The "metabolic memory": Is more than just tight glucose control necessary to prevent diabetic complications?
-
19066300 1:CAS:528:DC%2BD1MXhvFCqs7Y%3D 10.1210/jc.2008-1824
-
A. Ceriello, M. Ihnat, J. Thorpe, The "metabolic memory": is more than just tight glucose control necessary to prevent diabetic complications? J. Clin. Endocrinol. Metab. 94(2), 410-415 (2009)
-
(2009)
J. Clin. Endocrinol. Metab.
, vol.94
, Issue.2
, pp. 410-415
-
-
Ceriello, A.1
Ihnat, M.2
Thorpe, J.3
-
45
-
-
42549110366
-
Suppression of renal alpha-dicarbonyl compounds generated following ureteral obstruction by kidney specific alpha-dicarbonyl/l-xylulose reductase
-
18079483 1:CAS:528:DC%2BD1cXmtFynsLc%3D 10.1196/annals.1433.003
-
H. Odani, J. Asami, A. Ishii, K. Oide, T. Sudo, A. Nakamura, N. Miyata, N. Otsuka, K. Maeda, J. Nakagawa, Suppression of renal alpha-dicarbonyl compounds generated following ureteral obstruction by kidney specific alpha-dicarbonyl/l-xylulose reductase. Ann. N. Y. Acad. Sci. 1126, 320-324 (2008)
-
(2008)
Ann. N. Y. Acad. Sci.
, vol.1126
, pp. 320-324
-
-
Odani, H.1
Asami, J.2
Ishii, A.3
Oide, K.4
Sudo, T.5
Nakamura, A.6
Miyata, N.7
Otsuka, N.8
Maeda, K.9
Nakagawa, J.10
-
46
-
-
84862688640
-
Methylglyoxal, glyoxalase 1 and the dicarbonyl proteome
-
20963454 1:CAS:528:DC%2BC38XjsVWhsrc%3D 10.1007/s00726-010-0783-0
-
N. Rabbani, P.J. Thornalley, Methylglyoxal, glyoxalase 1 and the dicarbonyl proteome. Amino Acids 42(4), 1133-1142 (2012)
-
(2012)
Amino Acids
, vol.42
, Issue.4
, pp. 1133-1142
-
-
Rabbani, N.1
Thornalley, P.J.2
-
47
-
-
82055200076
-
Human aldo-keto reductase AKR7A2 protects against the cytotoxicity and mutagenicity of reactive aldehydes and lowers intracellular reactive oxygen species in hamster V79-4 cells
-
22001351 1:CAS:528:DC%2BC3MXhs1Oqs7fM 10.1016/j.cbi.2011.09.007
-
D. Li, M. Ferrari, E. Ellis, Human aldo-keto reductase AKR7A2 protects against the cytotoxicity and mutagenicity of reactive aldehydes and lowers intracellular reactive oxygen species in hamster V79-4 cells. Chem. Biol. Interact. 195(1), 25-34 (2012)
-
(2012)
Chem. Biol. Interact.
, vol.195
, Issue.1
, pp. 25-34
-
-
Li, D.1
Ferrari, M.2
Ellis, E.3
-
48
-
-
70350543787
-
Reductive metabolism of AGE precursors: A metabolic route for preventing AGE accumulation in cardiovascular tissue
-
19651811 1:CAS:528:DC%2BD1MXhsVChtrfK 10.2337/db09-0375
-
S. Baba, O. Barski, Y. Ahmed, T. O'Toole, D.J. Conklin, A. Bhatnagar, S. Srivastava, Reductive metabolism of AGE precursors: a metabolic route for preventing AGE accumulation in cardiovascular tissue. Diabetes 58(11), 2486-2497 (2009)
-
(2009)
Diabetes
, vol.58
, Issue.11
, pp. 2486-2497
-
-
Baba, S.1
Barski, O.2
Ahmed, Y.3
O'Toole, T.4
Conklin, D.J.5
Bhatnagar, A.6
Srivastava, S.7
-
49
-
-
84859634390
-
Cloning and characterization of AKR4C14, a rice aldoketo reductase from Thai Jasmine rice
-
22101802 1:CAS:528:DC%2BC3MXhsV2lsLrI 10.1007/s10930-011-9371-8
-
R. Narawongsanont, S. Kabinpong, B. Auiyawong, C. Tantitadapitak, Cloning and characterization of AKR4C14, a rice aldoketo reductase from Thai Jasmine rice. Protein J. 31(1), 35-42 (2012)
-
(2012)
Protein J.
, vol.31
, Issue.1
, pp. 35-42
-
-
Narawongsanont, R.1
Kabinpong, S.2
Auiyawong, B.3
Tantitadapitak, C.4
-
50
-
-
79957578430
-
Aldose reductase (AKR1B3) regulates the accumulation of advanced glycosylation end products (AGEs) and the expression of AGE receptor (RAGE)
-
21276777 1:CAS:528:DC%2BC3MXmvFais74%3D 10.1016/j.cbi.2011.01.024
-
S. Baba, J. Hellmann, S. Srivastava, A. Bhatnagar, Aldose reductase (AKR1B3) regulates the accumulation of advanced glycosylation end products (AGEs) and the expression of AGE receptor (RAGE). Chem. Biol. Interact. 191(1-3), 357-363 (2011)
-
(2011)
Chem. Biol. Interact.
, vol.191
, Issue.1-3
, pp. 357-363
-
-
Baba, S.1
Hellmann, J.2
Srivastava, S.3
Bhatnagar, A.4
-
51
-
-
34447252547
-
Methylglyoxal suppresses TNF-α-induced NF-κB activation by inhibiting NF-κB DNA-binding
-
17617381 1:CAS:528:DC%2BD2sXnslWjsr8%3D 10.1016/j.bcp.2007.05.026
-
M. Laga, A. Cottyn, F. van Herreweghe, W. Vanden Berghe, G. Haegeman, P. Van Oostveldt, J. Vandekerckhove, K. Vancompernolle, Methylglyoxal suppresses TNF-α-induced NF-κB activation by inhibiting NF-κB DNA-binding. Biochem. Pharmacol. 74(4), 579-589 (2007)
-
(2007)
Biochem. Pharmacol.
, vol.74
, Issue.4
, pp. 579-589
-
-
Laga, M.1
Cottyn, A.2
Van Herreweghe, F.3
Vanden Berghe, W.4
Haegeman, G.5
Van Oostveldt, P.6
Vandekerckhove, J.7
Vancompernolle, K.8
-
52
-
-
84857233918
-
Cathepsins D and L reduce the toxicity of advanced glycation end products
-
22245096 1:CAS:528:DC%2BC38XjtV2qs7w%3D 10.1016/j.freeradbiomed.2011.12. 021
-
S. Grimm, M. Horlacher, B. Catalgol, A. Hoehn, T. Reinheckel, T. Grune, Cathepsins D and L reduce the toxicity of advanced glycation end products. Free Radic. Biol. Med. 52(6), 1011-1023 (2012)
-
(2012)
Free Radic. Biol. Med.
, vol.52
, Issue.6
, pp. 1011-1023
-
-
Grimm, S.1
Horlacher, M.2
Catalgol, B.3
Hoehn, A.4
Reinheckel, T.5
Grune, T.6
-
53
-
-
77958517405
-
Methylglyoxal alters the function and stability of critical components of the protein quality control
-
20885985 10.1371/journal.pone.0013007 1:CAS:528:DC%2BC3cXht1eksbrM
-
C. Bento, F. Marques, R. Fernandes, P. Pereira, Methylglyoxal alters the function and stability of critical components of the protein quality control. PLoS One 5(9), e13007 (2010)
-
(2010)
PLoS One
, vol.5
, Issue.9
, pp. 13007
-
-
Bento, C.1
Marques, F.2
Fernandes, R.3
Pereira, P.4
-
54
-
-
17444380766
-
Renal clearance of glycolaldehyde- and methylglyoxal-modified proteins in mice is mediated by mesangial cells through a class A scavenger receptor (SR-A)
-
15654600 1:CAS:528:DC%2BD2MXhvF2rur4%3D 10.1007/s00125-004-1646-6
-
K. Nakajou, S. Horiuchi, M. Sakai, N. Haraguchi, M. Tanaka, M. Takeya, M. Otagiri, Renal clearance of glycolaldehyde- and methylglyoxal-modified proteins in mice is mediated by mesangial cells through a class A scavenger receptor (SR-A). Diabetologia 48(2), 317-327 (2005)
-
(2005)
Diabetologia
, vol.48
, Issue.2
, pp. 317-327
-
-
Nakajou, K.1
Horiuchi, S.2
Sakai, M.3
Haraguchi, N.4
Tanaka, M.5
Takeya, M.6
Otagiri, M.7
-
55
-
-
38349152722
-
Pyridoxamine protects proteins from functional damage by 3-deoxyglucosone: Mechanism of action of pyridoxamine
-
18161948 1:CAS:528:DC%2BD2sXhsVOntb%2FM 10.1021/bi701190s
-
S. Chetyrkin, W. Zhang, B. Hudson, A. Serianni, P. Voziyan, Pyridoxamine protects proteins from functional damage by 3-deoxyglucosone: mechanism of action of pyridoxamine. Biochemistry 47(3), 997-1006 (2008)
-
(2008)
Biochemistry
, vol.47
, Issue.3
, pp. 997-1006
-
-
Chetyrkin, S.1
Zhang, W.2
Hudson, B.3
Serianni, A.4
Voziyan, P.5
-
56
-
-
84863294250
-
Accumulation of argpyrimidine, a methylglyoxal-derived advanced glycation end product, increases apoptosis of lens epithelial cells both in vitro and in vivo
-
22139526 10.3858/emm.2012.44.2.012 1:CAS:528:DC%2BC38XmtlymtLk%3D
-
J. Kim, O. Kim, C. Kim, E. Sohn, K. Jo, J. Kim, Accumulation of argpyrimidine, a methylglyoxal-derived advanced glycation end product, increases apoptosis of lens epithelial cells both in vitro and in vivo. Exp. Mol. Med. 44(2), 167-175 (2012)
-
(2012)
Exp. Mol. Med.
, vol.44
, Issue.2
, pp. 167-175
-
-
Kim, J.1
Kim, O.2
Kim, C.3
Sohn, E.4
Jo, K.5
Kim, J.6
-
57
-
-
80053019857
-
Topical application of l-arginine blocks advanced glycation by ascorbic acid in the lens of hSVCT2 transgenic mice
-
21897744 1:CAS:528:DC%2BC3MXhtF2gurrP
-
X. Fan, L. Xiaoqin, B. Potts, C. Strauch, I. Nemet, V. Monnier, Topical application of l-arginine blocks advanced glycation by ascorbic acid in the lens of hSVCT2 transgenic mice. Mol. Vis. 17, 2221-2227 (2011)
-
(2011)
Mol. Vis.
, vol.17
, pp. 2221-2227
-
-
Fan, X.1
Xiaoqin, L.2
Potts, B.3
Strauch, C.4
Nemet, I.5
Monnier, V.6
-
58
-
-
79954502010
-
Genistein inhibits advanced glycation end product formation by trapping methylglyoxal
-
21344933 1:CAS:528:DC%2BC3MXitlKlsLw%3D 10.1021/tx100457h
-
L. Lv, X. Shao, H. Chen, C. Ho, S. Sang, Genistein inhibits advanced glycation end product formation by trapping methylglyoxal. Chem. Res. Toxicol. 24(4), 579-586 (2011)
-
(2011)
Chem. Res. Toxicol.
, vol.24
, Issue.4
, pp. 579-586
-
-
Lv, L.1
Shao, X.2
Chen, H.3
Ho, C.4
Sang, S.5
-
59
-
-
74549163524
-
Alagebrium attenuates acute methylglyoxal-induced glucose intolerance in Sprague-Dawley rats
-
20002105 1:CAS:528:DC%2BC3cXhtFynt7g%3D 10.1111/j.1476-5381.2009.00469.x
-
A. Dhar, K. Desai, L. Wu, Alagebrium attenuates acute methylglyoxal-induced glucose intolerance in Sprague-Dawley rats. Br. J. Pharmacol. 159(1), 166-175 (2010)
-
(2010)
Br. J. Pharmacol.
, vol.159
, Issue.1
, pp. 166-175
-
-
Dhar, A.1
Desai, K.2
Wu, L.3
-
60
-
-
80052080353
-
Cranberry phytochemicals inhibit glycation of human hemoglobin and serum albumin by scavenging reactive carbonyls
-
21826359 1:CAS:528:DC%2BC3MXhtVOns7fJ 10.1039/c1fo10087d
-
H. Liu, H. Liu, W. Wang, C. Khoo, J. Taylor, L. Gu, Cranberry phytochemicals inhibit glycation of human hemoglobin and serum albumin by scavenging reactive carbonyls. Food Funct. 2(8), 475-482 (2011)
-
(2011)
Food Funct.
, vol.2
, Issue.8
, pp. 475-482
-
-
Liu, H.1
Liu, H.2
Wang, W.3
Khoo, C.4
Taylor, J.5
Gu, L.6
-
61
-
-
84863024147
-
Phlorotannins from brown algae (Fucus vesiculosus) inhibited the formation of advanced glycation endproducts by scavenging reactive carbonyls
-
22248148 1:CAS:528:DC%2BC38XntlantA%3D%3D 10.1021/jf204112f
-
H. Liu, L. Gu, Phlorotannins from brown algae (Fucus vesiculosus) inhibited the formation of advanced glycation endproducts by scavenging reactive carbonyls. J. Agric. Food Chem. 60(5), 1326-1334 (2012)
-
(2012)
J. Agric. Food Chem.
, vol.60
, Issue.5
, pp. 1326-1334
-
-
Liu, H.1
Gu, L.2
-
62
-
-
44849103012
-
Dietary soy isoflavones increase insulin secretion and prevent the development of diabetic cataracts in streptozotocin-induced diabetic rats
-
19083447 1:CAS:528:DC%2BD1cXnt1Kqtrg%3D 10.1016/j.nutres.2008.03.009
-
M. Lu, R. Wang, X. Song, R. Chibbar, X. Wang, L. Wu, Q. Meng, Dietary soy isoflavones increase insulin secretion and prevent the development of diabetic cataracts in streptozotocin-induced diabetic rats. Nutr. Res. 28(7), 464-471 (2008)
-
(2008)
Nutr. Res.
, vol.28
, Issue.7
, pp. 464-471
-
-
Lu, M.1
Wang, R.2
Song, X.3
Chibbar, R.4
Wang, X.5
Wu, L.6
Meng, Q.7
-
63
-
-
79959596092
-
Fisetin lowers methylglyoxal dependent protein glycation and limits the complications of diabetes
-
21738623 1:CAS:528:DC%2BC3MXot1yqsbc%3D 10.1371/journal.pone.0021226
-
P. Maher, R. Dargusch, J. Ehren, S. Okada, K. Sharma, D. Schubert, Fisetin lowers methylglyoxal dependent protein glycation and limits the complications of diabetes. PLoS One 6(6), e21226 (2011)
-
(2011)
PLoS One
, vol.6
, Issue.6
, pp. 21226
-
-
Maher, P.1
Dargusch, R.2
Ehren, J.3
Okada, S.4
Sharma, K.5
Schubert, D.6
-
64
-
-
73649098762
-
Anti-glycative effects of oleanolic acid and ursolic acid in kidney of diabetic mice
-
19917277 1:CAS:528:DC%2BC3cXnvFOqtg%3D%3D 10.1016/j.ejphar.2009.11.019
-
Z. Wang, C. Hsu, C. Huang, M. Yin, Anti-glycative effects of oleanolic acid and ursolic acid in kidney of diabetic mice. Eur. J. Pharmacol. 628(1-3), 255-260 (2010)
-
(2010)
Eur. J. Pharmacol.
, vol.628
, Issue.1-3
, pp. 255-260
-
-
Wang, Z.1
Hsu, C.2
Huang, C.3
Yin, M.4
-
65
-
-
84856282540
-
Ellagic acid, a new antiglycating agent: Its inhibition of NÏμ-(carboxymethyl)lysine
-
22060242 1:CAS:528:DC%2BC38XhsVOms7c%3D 10.1042/BJ20110846
-
P. Muthenna, C. Akileshwari, G. Reddy, Ellagic acid, a new antiglycating agent: its inhibition of NÏμ-(carboxymethyl)lysine. Biochem. J. 442(1), 221-230 (2012)
-
(2012)
Biochem. J.
, vol.442
, Issue.1
, pp. 221-230
-
-
Muthenna, P.1
Akileshwari, C.2
Reddy, G.3
-
66
-
-
78649965876
-
Eicosapentaenoic acid restores diabetic tubular injury through regulating oxidative stress and mitochondrial apoptosis
-
20844021 1:CAS:528:DC%2BC3cXhs1elsb%2FM 10.1152/ajprenal.00637.2009
-
S. Taneda, K. Honda, K. Tomidokoro, K. Uto, K. Nitta, H. Oda, Eicosapentaenoic acid restores diabetic tubular injury through regulating oxidative stress and mitochondrial apoptosis. Am. J. Physiol. Renal Physiol. 299(6), F1451-F1461 (2010)
-
(2010)
Am. J. Physiol. Renal Physiol.
, vol.299
, Issue.6
-
-
Taneda, S.1
Honda, K.2
Tomidokoro, K.3
Uto, K.4
Nitta, K.5
Oda, H.6
-
67
-
-
33845677195
-
Structural and functional changes in human insulin induced by methylglyoxal
-
16723378 1:CAS:528:DC%2BD28XmvV2hu74%3D 10.1096/fj.05-5478fje
-
X. Jia, D.J. Olson, A.R. Ross, L. Wu, Structural and functional changes in human insulin induced by methylglyoxal. FASEB J. 20, 1555-1557 (2006)
-
(2006)
FASEB J.
, vol.20
, pp. 1555-1557
-
-
Jia, X.1
Olson, D.J.2
Ross, A.R.3
Wu, L.4
-
68
-
-
33845921213
-
Site-selective modifications of arginine residues in human hemoglobin induced by methylglyoxal
-
17176087 1:CAS:528:DC%2BD28XhtlChurrF 10.1021/bi061410o
-
Y. Gao, Y. Wang, Site-selective modifications of arginine residues in human hemoglobin induced by methylglyoxal. Biochemistry 45, 15654-15660 (2006)
-
(2006)
Biochemistry
, vol.45
, pp. 15654-15660
-
-
Gao, Y.1
Wang, Y.2
-
69
-
-
35248871238
-
Methylglyoxal induces advanced glycation end product (AGEs) formation and dysfunction of PDGF receptor-beta: Implications for diabetic atherosclerosis
-
17504976 1:CAS:528:DC%2BD2sXhtFKntbvI 10.1096/fj.06-7536com
-
A. Cantero, M. Portero-Otin, V. Ayala, N. Auge, M. Sanson, M. Elbaz, J. Thiers, R. Pamplona, R. Salvayre, A. Negre-Salvayre, Methylglyoxal induces advanced glycation end product (AGEs) formation and dysfunction of PDGF receptor-beta: implications for diabetic atherosclerosis. FASEB J. 21, 3096-3106 (2007)
-
(2007)
FASEB J.
, vol.21
, pp. 3096-3106
-
-
Cantero, A.1
Portero-Otin, M.2
Ayala, V.3
Auge, N.4
Sanson, M.5
Elbaz, M.6
Thiers, J.7
Pamplona, R.8
Salvayre, R.9
Negre-Salvayre, A.10
-
70
-
-
38949167689
-
Effect of methylglyoxal modification on stress-induced aggregation of client proteins and their chaperoning by human alphaA crystallin
-
17941823 1:CAS:528:DC%2BD1cXls1Kmsg%3D%3D 10.1042/BJ20071006
-
A. Biswas, B. Wang, M. Miyagi, R.H. Nagaraj, Effect of methylglyoxal modification on stress-induced aggregation of client proteins and their chaperoning by human alphaA crystallin. Biochem. J. 409, 771-777 (2008)
-
(2008)
Biochem. J.
, vol.409
, pp. 771-777
-
-
Biswas, A.1
Wang, B.2
Miyagi, M.3
Nagaraj, R.H.4
-
71
-
-
0030919275
-
N-epsilon-(carboxyethyl)lysine, a product of the chemical modification of proteins by methylglyoxal, increases with age in human lens proteins
-
9182719 1:CAS:528:DyaK2sXjvFGmtLc%3D
-
M.U. Ahmed, F. Brinkmann, T.P. Degenhardt, S. Thorpe, J. Baynes, N-epsilon-(carboxyethyl)lysine, a product of the chemical modification of proteins by methylglyoxal, increases with age in human lens proteins. Biochem. J. 324, 565-570 (1997)
-
(1997)
Biochem. J.
, vol.324
, pp. 565-570
-
-
Ahmed, M.U.1
Brinkmann, F.2
Degenhardt, T.P.3
Thorpe, S.4
Baynes, J.5
-
72
-
-
42549117517
-
The dicarbonyl proteome: Proteins susceptible to dicarbonyl glycation at functional sites in health, aging, and disease
-
18448805 1:CAS:528:DC%2BD1cXmtFygurg%3D 10.1196/annals.1433.043
-
N. Rabbani, P. Thornalley, The dicarbonyl proteome: proteins susceptible to dicarbonyl glycation at functional sites in health, aging, and disease. Ann. N. Y. Acad. Sci. 1126, 124-127 (2008)
-
(2008)
Ann. N. Y. Acad. Sci.
, vol.1126
, pp. 124-127
-
-
Rabbani, N.1
Thornalley, P.2
-
73
-
-
84855826057
-
Hydroimidazolone modification of the conserved Arg12 in small heat shock proteins: Studies on the structure and chaperone function using mutant mimics
-
22272318 1:CAS:528:DC%2BC38XhslKmtr0%3D 10.1371/journal.pone.0030257
-
R. Nagaraj, A. Panda, S. Shanthakumar, P. Santhoshkumar, N. Pasupuleti, B. Wang, A. Biswas, Hydroimidazolone modification of the conserved Arg12 in small heat shock proteins: studies on the structure and chaperone function using mutant mimics. PLoS One 7(1), e30257 (2012)
-
(2012)
PLoS One
, vol.7
, Issue.1
, pp. 30257
-
-
Nagaraj, R.1
Panda, A.2
Shanthakumar, S.3
Santhoshkumar, P.4
Pasupuleti, N.5
Wang, B.6
Biswas, A.7
-
74
-
-
65949097068
-
Glyoxalase i overexpression ameliorates renal ischemic-reperfusion injury in rats
-
19211689 1:CAS:528:DC%2BD1MXkvVyntrw%3D 10.1152/ajprenal.90575.2008
-
T. Kumagai, M. Nangaku, I. Kojima, R. Nagai, J. Ingelfinger, T. Miyata, T. Fujita, R. Inagi, Glyoxalase I overexpression ameliorates renal ischemic-reperfusion injury in rats. Am. J. Physiol. Renal Physiol. 296, F912-F921 (2009)
-
(2009)
Am. J. Physiol. Renal Physiol.
, vol.296
-
-
Kumagai, T.1
Nangaku, M.2
Kojima, I.3
Nagai, R.4
Ingelfinger, J.5
Miyata, T.6
Fujita, T.7
Inagi, R.8
-
75
-
-
84860751778
-
Methylglyoxal causes structural and functional alterations in adipose tissue independently of obesity
-
22364223 1:CAS:528:DC%2BC38XmsFOgtb4%3D 10.3109/13813455.2012.658065
-
P. Matafome, D. Santos-Silva, J. Crisóstomo, T. Rodrigues, L. Rodrigues, C. Sena, P. Pereira, R. Seiça, Methylglyoxal causes structural and functional alterations in adipose tissue independently of obesity. Arch. Physiol. Biochem. 118(2), 58-68 (2012)
-
(2012)
Arch. Physiol. Biochem.
, vol.118
, Issue.2
, pp. 58-68
-
-
Matafome, P.1
Santos-Silva, D.2
Crisóstomo, J.3
Rodrigues, T.4
Rodrigues, L.5
Sena, C.6
Pereira, P.7
Seiça, R.8
-
76
-
-
0036237275
-
The Maillard hypothesis on aging: Time to focus on DNA
-
11976210 1:CAS:528:DC%2BD38XktFWqu7k%3D 10.1111/j.1749-6632.2002.tb02107. x
-
J.W. Baynes, The Maillard hypothesis on aging: time to focus on DNA. Ann. N. Y. Acad. Sci. 959, 360-367 (2002)
-
(2002)
Ann. N. Y. Acad. Sci.
, vol.959
, pp. 360-367
-
-
Baynes, J.W.1
-
77
-
-
0037469379
-
DNA damage by carbonyl stress in human skin cells
-
12517411 1:CAS:528:DC%2BD3sXmvVOg
-
M.J. Roberts, G.T. Wondrak, D.C. Laurean, M.K. Jacobson, E. Jacobson, DNA damage by carbonyl stress in human skin cells. Mutat. Res. 522(1-2), 45-56 (2003)
-
(2003)
Mutat. Res.
, vol.522
, Issue.1-2
, pp. 45-56
-
-
Roberts, M.J.1
Wondrak, G.T.2
Laurean, D.C.3
Jacobson, M.K.4
Jacobson, E.5
-
78
-
-
0348136791
-
Protecting the genome: Defence against nucleotide glycation and emerging role of glyoxalase i overexpression in multidrug resistance in cancer chemotherapy
-
14641066 1:CAS:528:DC%2BD3sXps12jtrc%3D 10.1042/BST0311372
-
P.J. Thornalley, Protecting the genome: defence against nucleotide glycation and emerging role of glyoxalase I overexpression in multidrug resistance in cancer chemotherapy. Biochem. Soc. Trans. 31(Pt 6), 1372-1377 (2003)
-
(2003)
Biochem. Soc. Trans.
, vol.31
, Issue.PART 6
, pp. 1372-1377
-
-
Thornalley, P.J.1
-
79
-
-
84859716804
-
Structural modifications of human albumin in diabetes
-
22349032 1:CAS:528:DC%2BC38XlvVSltrs%3D 10.1016/j.diabet.2011.11.002
-
A. Guerin-Dubourg, A. Catan, E. Bourdon, P. Rondeau, Structural modifications of human albumin in diabetes. Diabetes Metab. 38(2), 171-178 (2012)
-
(2012)
Diabetes Metab.
, vol.38
, Issue.2
, pp. 171-178
-
-
Guerin-Dubourg, A.1
Catan, A.2
Bourdon, E.3
Rondeau, P.4
-
80
-
-
0037246065
-
Advanced glycation end products inhibit de novo protein synthesis and induce TGF-beta overexpression in proximal tubular cells
-
12631112 1:CAS:528:DC%2BD3sXht1yrs7c%3D 10.1046/j.1523-1755.2003.00752.x
-
S. Yamagishi, Y. Inagaki, T. Okamoto, S. Amano, K. Koga, M. Takeuchi, Advanced glycation end products inhibit de novo protein synthesis and induce TGF-beta overexpression in proximal tubular cells. Kidney Int. 63(2), 464-473 (2003)
-
(2003)
Kidney Int.
, vol.63
, Issue.2
, pp. 464-473
-
-
Yamagishi, S.1
Inagaki, Y.2
Okamoto, T.3
Amano, S.4
Koga, K.5
Takeuchi, M.6
-
81
-
-
80053070121
-
Fibrin(ogen) may be an important target for methylglyoxal-derived AGE modification in elastic arteries of humans
-
21844128 10.1177/1479164111416831
-
T. Lund, A. Svindland, M. Pepaj, A. Jensen, J. Berg, B. Kilhovd, K. Hanssen, Fibrin(ogen) may be an important target for methylglyoxal-derived AGE modification in elastic arteries of humans. Diab. Vasc. Dis. Res. 8(4), 284-294 (2011)
-
(2011)
Diab. Vasc. Dis. Res.
, vol.8
, Issue.4
, pp. 284-294
-
-
Lund, T.1
Svindland, A.2
Pepaj, M.3
Jensen, A.4
Berg, J.5
Kilhovd, B.6
Hanssen, K.7
-
82
-
-
84859498734
-
Exploring mechanisms of diabetes-related macrovascular complications: Role of methylglyoxal, a metabolite of glucose on regulation of vascular contractility
-
22333481 1:CAS:528:DC%2BC38XkvVKlsLs%3D 10.1254/jphs.11R12CP
-
M. Mukohda, M. Okada, Y. Hara, H. Yamawaki, Exploring mechanisms of diabetes-related macrovascular complications: role of methylglyoxal, a metabolite of glucose on regulation of vascular contractility. J. Pharmacol. Sci. 118(3), 303-310 (2012)
-
(2012)
J. Pharmacol. Sci.
, vol.118
, Issue.3
, pp. 303-310
-
-
Mukohda, M.1
Okada, M.2
Hara, Y.3
Yamawaki, H.4
-
83
-
-
84855988671
-
Long-term methylglyoxal treatment impairs smooth muscle contractility in organ-cultured rat mesenteric artery
-
21884795 1:CAS:528:DC%2BC38Xht1OntLY%3D 10.1016/j.phrs.2011.08.005
-
M. Mukohda, T. Morita, M. Okada, Y. Hara, H. Yamawaki, Long-term methylglyoxal treatment impairs smooth muscle contractility in organ-cultured rat mesenteric artery. Pharmacol. Res. 65(1), 91-99 (2012)
-
(2012)
Pharmacol. Res.
, vol.65
, Issue.1
, pp. 91-99
-
-
Mukohda, M.1
Morita, T.2
Okada, M.3
Hara, Y.4
Yamawaki, H.5
-
84
-
-
70349909975
-
Modification of collagen IV by glucose or methylglyoxal alters distinct mesangial cell functions
-
19608705 1:CAS:528:DC%2BD1MXhtlSrsbbJ 10.1681/ASN.2008080900
-
A. Pozzi, R. Zent, S. Chetyrkin, C. Borza, N. Bulus, P. Chuang, D. Chen, B. Hudson, P. Voziyan, Modification of collagen IV by glucose or methylglyoxal alters distinct mesangial cell functions. J. Am. Soc. Nephrol. 20(10), 2119-2125 (2009)
-
(2009)
J. Am. Soc. Nephrol.
, vol.20
, Issue.10
, pp. 2119-2125
-
-
Pozzi, A.1
Zent, R.2
Chetyrkin, S.3
Borza, C.4
Bulus, N.5
Chuang, P.6
Chen, D.7
Hudson, B.8
Voziyan, P.9
-
85
-
-
25844476029
-
Mechanisms of perturbation of integrin-mediated cell-matrix interactions by reactive carbonyl compounds and its implication for pathogenesis of diabetic nephropathy
-
16186398 1:CAS:528:DC%2BD2MXhtV2rs7%2FL 10.2337/diabetes.54.10.2952
-
V. Pedchenko, S. Chetyrkin, P. Chuang, A. Ham, M. Sallem, P. Mathieson, B. Hudson, P. Voziyan, Mechanisms of perturbation of integrin-mediated cell-matrix interactions by reactive carbonyl compounds and its implication for pathogenesis of diabetic nephropathy. Diabetes 54, 2952-2960 (2005)
-
(2005)
Diabetes
, vol.54
, pp. 2952-2960
-
-
Pedchenko, V.1
Chetyrkin, S.2
Chuang, P.3
Ham, A.4
Sallem, M.5
Mathieson, P.6
Hudson, B.7
Voziyan, P.8
-
86
-
-
35649026775
-
High glucose increases angiopoietin-2 transcription in microvascular endothelial cells through methylglyoxal modification of mSin3A
-
17670746 1:CAS:528:DC%2BD2sXhtFGgs73O 10.1074/jbc.M704703200
-
D. Yao, T. Taguchi, T. Matsumura, R. Pestell, D. Edelstein, I. Giardino, G. Suske, N. Rabbani, P. Thornalley, V. Sarthy, H. Hammes, M. Brownlee, High glucose increases angiopoietin-2 transcription in microvascular endothelial cells through methylglyoxal modification of mSin3A. J. Biol. Chem. 282, 31038-31045 (2007)
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 31038-31045
-
-
Yao, D.1
Taguchi, T.2
Matsumura, T.3
Pestell, R.4
Edelstein, D.5
Giardino, I.6
Suske, G.7
Rabbani, N.8
Thornalley, P.9
Sarthy, V.10
Hammes, H.11
Brownlee, M.12
-
87
-
-
69449108536
-
The molecular basis for impaired hypoxia-induced VEGF expression in diabetic tissues
-
19666581 1:CAS:528:DC%2BD1MXhtVOitrrF 10.1073/pnas.0906670106
-
H. Thangarajah, D. Yao, E. Chang, Y. Shi, L. Jazayeri, I. Vial, R. Galiano, X. Du, R. Grogan, M. Galvez, M. Januszyk, M. Brownlee, G. Gurtner, The molecular basis for impaired hypoxia-induced VEGF expression in diabetic tissues. Proc. Natl. Acad. Sci. USA 106(32), 13505-13510 (2009)
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, Issue.32
, pp. 13505-13510
-
-
Thangarajah, H.1
Yao, D.2
Chang, E.3
Shi, Y.4
Jazayeri, L.5
Vial, I.6
Galiano, R.7
Du, X.8
Grogan, R.9
Galvez, M.10
Januszyk, M.11
Brownlee, M.12
Gurtner, G.13
-
88
-
-
78649753203
-
The chaperone-dependent ubiquitin ligase chip targets HIF-1α for degradation in the presence of methylglyoxal
-
21124777 1:CAS:528:DC%2BC3cXhsFaqu7nP 10.1371/journal.pone.0015062
-
C. Bento, R. Fernandes, J. Ramalho, C. Marques, F. Shang, A. Taylor, P. Pereira, The chaperone-dependent ubiquitin ligase chip targets HIF-1α for degradation in the presence of methylglyoxal. PLoS One 5(11), e15062 (2010)
-
(2010)
PLoS One
, vol.5
, Issue.11
, pp. 15062
-
-
Bento, C.1
Fernandes, R.2
Ramalho, J.3
Marques, C.4
Shang, F.5
Taylor, A.6
Pereira, P.7
-
89
-
-
77955835661
-
Methylglyoxal-induced imbalance in the ratio of vascular endothelial growth factor to angiopoietin 2 secreted by retinal pigment epithelial cells leads to endothelial dysfunction
-
20562294 1:CAS:528:DC%2BC3cXhtlGjt7jP
-
C. Bento, R. Fernandes, P. Matafome, C. Sena, R. Seiça, P. Pereira, Methylglyoxal-induced imbalance in the ratio of vascular endothelial growth factor to angiopoietin 2 secreted by retinal pigment epithelial cells leads to endothelial dysfunction. Exp. Physiol. 95(9), 955-970 (2010)
-
(2010)
Exp. Physiol.
, vol.95
, Issue.9
, pp. 955-970
-
-
Bento, C.1
Fernandes, R.2
Matafome, P.3
Sena, C.4
Seiça, R.5
Pereira, P.6
-
90
-
-
0035969865
-
Metabolism of the 2-oxoaldehyde methylglyoxal by aldose reductase and by glyoxalase-I: Roles for glutathione in both enzymes and implications for diabetic complications
-
11306074 10.1016/S0009-2797(00)00298-2
-
D. Vander Jagt, R. Hassebrook, L. Hunsaker, W. Brown, R. Royer, Metabolism of the 2-oxoaldehyde methylglyoxal by aldose reductase and by glyoxalase-I: roles for glutathione in both enzymes and implications for diabetic complications. Chem. Biol. Interact. 130-132, 549-562 (2001)
-
(2001)
Chem. Biol. Interact.
, vol.130-132
, pp. 549-562
-
-
Vander Jagt, D.1
Hassebrook, R.2
Hunsaker, L.3
Brown, W.4
Royer, R.5
-
91
-
-
0035891320
-
Inhibition of JNK activation through NF-κB target genes
-
10.1038/35104568
-
G. Tang, Y. Minemoto, B. Dibling, N. Purcell, Z. Li, M. Karin, A. Lin, Inhibition of JNK activation through NF-κB target genes. Nature 414(6861), 6313-6317 (2001)
-
(2001)
Nature
, vol.414
, Issue.6861
, pp. 6313-6317
-
-
Tang, G.1
Minemoto, Y.2
Dibling, B.3
Purcell, N.4
Li, Z.5
Karin, M.6
Lin, A.7
-
92
-
-
77950362951
-
Hyperglycemia impairs proteasome function by methylglyoxal
-
20009088 1:CAS:528:DC%2BC3cXjslegur8%3D 10.2337/db08-1565
-
M. Queisser, D. Yao, S. Geisler, H. Hammes, G. Lochnit, E. Schleicher, M. Brownlee, K. Preissner, Hyperglycemia impairs proteasome function by methylglyoxal. Diabetes 59(3), 670-678 (2010)
-
(2010)
Diabetes
, vol.59
, Issue.3
, pp. 670-678
-
-
Queisser, M.1
Yao, D.2
Geisler, S.3
Hammes, H.4
Lochnit, G.5
Schleicher, E.6
Brownlee, M.7
Preissner, K.8
-
93
-
-
0142102552
-
Methylglyoxal modifies heat shock protein 27 in glomerular mesangial cells
-
12965214 1:CAS:528:DC%2BD3sXntVCjsbo%3D 10.1016/S0014-5793(03)00874-3
-
A.K. Padival, J. Crabb, R. Nagaraj, Methylglyoxal modifies heat shock protein 27 in glomerular mesangial cells. FEBS Lett. 551(1-3), 113-118 (2003)
-
(2003)
FEBS Lett.
, vol.551
, Issue.1-3
, pp. 113-118
-
-
Padival, A.K.1
Crabb, J.2
Nagaraj, R.3
-
94
-
-
43449126527
-
Free radical generation by methylglyoxal in tissues
-
18533368 1:CAS:528:DC%2BD1cXmtFamsL8%3D 10.1515/DMDI.2008.23.1-2.151
-
K. Desai, L. Wu, Free radical generation by methylglyoxal in tissues. Drug Metabol. Drug Interact. 23, 151-173 (2008)
-
(2008)
Drug Metabol. Drug Interact.
, vol.23
, pp. 151-173
-
-
Desai, K.1
Wu, L.2
-
95
-
-
0036196199
-
Increased methylglyoxal and oxidative stress in hypertensive rat vascular smooth muscle cells
-
11897769 1:CAS:528:DC%2BD38XisVegtb4%3D 10.1161/hy0302.105207
-
L. Wu, B. Juurlink, Increased methylglyoxal and oxidative stress in hypertensive rat vascular smooth muscle cells. Hypertension 39, 809-814 (2002)
-
(2002)
Hypertension
, vol.39
, pp. 809-814
-
-
Wu, L.1
Juurlink, B.2
-
96
-
-
10644266855
-
Methylglyoxal-induced nitric oxide and peroxynitrite production in vascular smooth muscle cells
-
15607912 1:CAS:528:DC%2BD2cXhtVyqsb%2FP 10.1016/j.freeradbiomed.2004.10. 034
-
T. Chang, R. Wang, L. Wu, Methylglyoxal-induced nitric oxide and peroxynitrite production in vascular smooth muscle cells. Free Radic. Biol. Med. 38, 286-293 (2005)
-
(2005)
Free Radic. Biol. Med.
, vol.38
, pp. 286-293
-
-
Chang, T.1
Wang, R.2
Wu, L.3
-
97
-
-
48849083804
-
Methylglyoxal production in vascular smooth muscle cells from different metabolic precursors
-
18702946 1:CAS:528:DC%2BD1cXhtVWit7jJ 10.1016/j.metabol.2008.04.014
-
A. Dhar, K. Desai, M. Kazachmov, P. Yu, L. Wu, Methylglyoxal production in vascular smooth muscle cells from different metabolic precursors. Metabolism 57, 1211-1220 (2008)
-
(2008)
Metabolism
, vol.57
, pp. 1211-1220
-
-
Dhar, A.1
Desai, K.2
Kazachmov, M.3
Yu, P.4
Wu, L.5
-
98
-
-
84859788536
-
Methylglyoxal promotes oxidative stress and endothelial dysfunction
-
22425979 1:CAS:528:DC%2BC38XlvFGiu7Y%3D 10.1016/j.phrs.2012.03.004
-
C. Sena, P. Matafome, J. Crisóstomo, L. Rodrigues, R. Fernandes, P. Pereira, R. Seiça, Methylglyoxal promotes oxidative stress and endothelial dysfunction. Pharmacol. Res. 65(5), 497-506 (2012)
-
(2012)
Pharmacol. Res.
, vol.65
, Issue.5
, pp. 497-506
-
-
Sena, C.1
Matafome, P.2
Crisóstomo, J.3
Rodrigues, L.4
Fernandes, R.5
Pereira, P.6
Seiça, R.7
-
99
-
-
3242664216
-
Methylglyoxal: A stimulus to neutrophil oxygen radical production in chronic renal failure?
-
15150351 1:CAS:528:DC%2BD2cXltVWks7g%3D 10.1093/ndt/gfh271
-
R. Ward, K. McLeish, Methylglyoxal: a stimulus to neutrophil oxygen radical production in chronic renal failure? Nephrol. Dial. Transplant. 19, 1702-1707 (2004)
-
(2004)
Nephrol. Dial. Transplant.
, vol.19
, pp. 1702-1707
-
-
Ward, R.1
McLeish, K.2
-
100
-
-
0029884823
-
Effects of methylglyoxal on platelet hydrogen peroxide accumulation, aggregation and release reaction
-
8640957 1:CAS:528:DyaK28XjsFansbc%3D
-
G. Leoncini, M. Poggi, Effects of methylglyoxal on platelet hydrogen peroxide accumulation, aggregation and release reaction. Cell Biochem. Funct. 14, 89-95 (1996)
-
(1996)
Cell Biochem. Funct.
, vol.14
, pp. 89-95
-
-
Leoncini, G.1
Poggi, M.2
-
101
-
-
0027176827
-
Has reactive oxygen a role in methylglyoxal toxicity? A study on cultured rat hepatocytes
-
8368947 1:CAS:528:DyaK3sXlsFelsrc%3D 10.1007/BF01973710
-
M.P. Kalapos, A. Littauer, H. de Groot, Has reactive oxygen a role in methylglyoxal toxicity? A study on cultured rat hepatocytes. Arch. Toxicol. 67, 369-372 (1993)
-
(1993)
Arch. Toxicol.
, vol.67
, pp. 369-372
-
-
Kalapos, M.P.1
Littauer, A.2
De Groot, H.3
-
102
-
-
1642274975
-
Methylglyoxal induces oxidative stress-dependent cell injury and up-regulation of interleukin-1beta and nerve growth factor in cultured hippocampal neuronal cells
-
15051519 10.1016/j.brainres.2004.01.066 1:CAS:528:DC%2BD2cXisF2itbY%3D
-
S. Di Loreto, V. Caracciolo, S. Colafarina, P. Sebastiani, A. Gasbarri, F. Amicarelli, Methylglyoxal induces oxidative stress-dependent cell injury and up-regulation of interleukin-1beta and nerve growth factor in cultured hippocampal neuronal cells. Brain Res. 1006, 157-167 (2004)
-
(2004)
Brain Res.
, vol.1006
, pp. 157-167
-
-
Di Loreto, S.1
Caracciolo, V.2
Colafarina, S.3
Sebastiani, P.4
Gasbarri, A.5
Amicarelli, F.6
-
103
-
-
0035399660
-
Glyoxal and methylglyoxal trigger distinct signals for map family kinases and caspase activation in human endothelial cells
-
11425486 1:CAS:528:DC%2BD3MXks1OltLo%3D 10.1016/S0891-5849(01)00550-0
-
A. Akhand, K. Hossain, H. Mitsui, M. Kato, T. Miyata, R. Inagi, J. Du, K. Takeda, Y. Kawamoto, H. Suzuki, K. Kurokawa, I. Nakashima, Glyoxal and methylglyoxal trigger distinct signals for map family kinases and caspase activation in human endothelial cells. Free Radic. Biol. Med. 31, 20-30 (2001)
-
(2001)
Free Radic. Biol. Med.
, vol.31
, pp. 20-30
-
-
Akhand, A.1
Hossain, K.2
Mitsui, H.3
Kato, M.4
Miyata, T.5
Inagi, R.6
Du, J.7
Takeda, K.8
Kawamoto, Y.9
Suzuki, H.10
Kurokawa, K.11
Nakashima, I.12
-
104
-
-
45749127330
-
Methylglyoxal induces prostaglandin E2 production in rat mesangial cells
-
18762725
-
A. Uriuhara, S. Miyata, B. Liu, H. Miyazaki, H. Kusunoki, H. Kojima, Y. Yamashita, K. Suzuki, K. Inaba, M. Kasuga, Methylglyoxal induces prostaglandin E2 production in rat mesangial cells. Kobe J. Med. Sci. 53(6), 305-315 (2008)
-
(2008)
Kobe J. Med. Sci.
, vol.53
, Issue.6
, pp. 305-315
-
-
Uriuhara, A.1
Miyata, S.2
Liu, B.3
Miyazaki, H.4
Kusunoki, H.5
Kojima, H.6
Yamashita, Y.7
Suzuki, K.8
Inaba, K.9
Kasuga, M.10
-
105
-
-
0033566287
-
Neurotoxicity of methylglyoxal and 3-deoxyglucosone on cultured cortical neurons: Synergism between glycation and oxidative stress, possibly involved in neurodegenerative diseases
-
10398306 1:CAS:528:DyaK1MXksFSlsL8%3D 10.1002/(SICI)1097-4547(19990715) 57:2<280: AID-JNR14>3.0.CO;2-U
-
S. Kikuchi, K. Shinpo, F. Moriwaka, Z. Makita, T. Miyata, K. Tashiro, Neurotoxicity of methylglyoxal and 3-deoxyglucosone on cultured cortical neurons: synergism between glycation and oxidative stress, possibly involved in neurodegenerative diseases. J. Neurosci. Res. 57, 280-289 (1999)
-
(1999)
J. Neurosci. Res.
, vol.57
, pp. 280-289
-
-
Kikuchi, S.1
Shinpo, K.2
Moriwaka, F.3
Makita, Z.4
Miyata, T.5
Tashiro, K.6
-
106
-
-
0141861127
-
Scavenging system efficiency is crucial for cell resistance to ROS-mediated methylglyoxal injury
-
14556850 1:CAS:528:DC%2BD3sXnvVOhtLw%3D 10.1016/S0891-5849(03)00438-6
-
F. Amicarelli, S. Colafarina, F. Cattani, A. Cimini, C. Di Ilio, M. Ceru, M. Miranda, Scavenging system efficiency is crucial for cell resistance to ROS-mediated methylglyoxal injury. Free Radic. Biol. Med. 35, 856-871 (2003)
-
(2003)
Free Radic. Biol. Med.
, vol.35
, pp. 856-871
-
-
Amicarelli, F.1
Colafarina, S.2
Cattani, F.3
Cimini, A.4
Di Ilio, C.5
Ceru, M.6
Miranda, M.7
-
107
-
-
0032124869
-
Modification of enzymatic antioxidants in retinal microvascular cells by glucose or advanced glycation end products
-
9655530 1:CAS:528:DyaK1cXkt1Ogu7c%3D 10.1016/S0891-5849(98)00071-9
-
C. Paget, M. Lecomte, D. Ruggiero, N. Wiernsperger, M. Lagarde, Modification of enzymatic antioxidants in retinal microvascular cells by glucose or advanced glycation end products. Free. Radic. Biol. Med. 25, 121-129 (1998)
-
(1998)
Free. Radic. Biol. Med.
, vol.25
, pp. 121-129
-
-
Paget, C.1
Lecomte, M.2
Ruggiero, D.3
Wiernsperger, N.4
Lagarde, M.5
-
108
-
-
64249090462
-
Methylglyoxal-induced mitochondrial dysfunction in vascular smooth muscle cells
-
19428325 1:CAS:528:DC%2BD1MXkvVSqtrs%3D 10.1016/j.bcp.2009.02.024
-
H. Wang, J. Liu, L. Wu, Methylglyoxal-induced mitochondrial dysfunction in vascular smooth muscle cells. Biochem. Pharmacol. 77, 1709-1716 (2009)
-
(2009)
Biochem. Pharmacol.
, vol.77
, pp. 1709-1716
-
-
Wang, H.1
Liu, J.2
Wu, L.3
-
109
-
-
77950884137
-
Oxidative stress and aging: Is methylglyoxal the hidden enemy?
-
20393592 1:CAS:528:DC%2BC3cXkvVylurc%3D 10.1139/Y10-001
-
K. Desai, T. Chang, H. Wang, A. Banigesh, A. Dhar, J. Liu, A. Untereiner, L. Wu, Oxidative stress and aging: is methylglyoxal the hidden enemy? Can. J. Physiol. Pharmacol. 88, 273-284 (2010)
-
(2010)
Can. J. Physiol. Pharmacol.
, vol.88
, pp. 273-284
-
-
Desai, K.1
Chang, T.2
Wang, H.3
Banigesh, A.4
Dhar, A.5
Liu, J.6
Untereiner, A.7
Wu, L.8
-
110
-
-
77449142258
-
Hyperglycemia-induced reactive oxygen species increase expression of the receptor for advanced glycation end products (RAGE) and RAGE ligands
-
19833897 1:CAS:528:DC%2BC3cXmtVKmtA%3D%3D 10.2337/db09-0801
-
D. Yao, M. Brownlee, Hyperglycemia-induced reactive oxygen species increase expression of the receptor for advanced glycation end products (RAGE) and RAGE ligands. Diabetes 59, 249-255 (2010)
-
(2010)
Diabetes
, vol.59
, pp. 249-255
-
-
Yao, D.1
Brownlee, M.2
-
111
-
-
0347381138
-
Glycation, inflammation, and RAGE: A scaffold for the macrovascular complications of diabetes and beyond
-
14670831 1:CAS:528:DC%2BD3sXpsFymtLk%3D 10.1161/01.RES.0000103862.26506. 3D
-
S. Yan, R. Ramasamy, Y. Naka, A. Schmidt, Glycation, inflammation, and RAGE: a scaffold for the macrovascular complications of diabetes and beyond. Circ. Res. 93(12), 1159-1169 (2003)
-
(2003)
Circ. Res.
, vol.93
, Issue.12
, pp. 1159-1169
-
-
Yan, S.1
Ramasamy, R.2
Naka, Y.3
Schmidt, A.4
-
112
-
-
84862682038
-
Advanced glycation endproducts: From precursors to RAGE: Round and round we go
-
20957395 1:CAS:528:DC%2BC38XjsVWhsrs%3D 10.1007/s00726-010-0773-2
-
R. Ramasamy, S. Yan, A. Schmidt, Advanced glycation endproducts: from precursors to RAGE: round and round we go. Amino Acids 42(4), 1151-1161 (2012)
-
(2012)
Amino Acids
, vol.42
, Issue.4
, pp. 1151-1161
-
-
Ramasamy, R.1
Yan, S.2
Schmidt, A.3
-
113
-
-
77953525199
-
Receptor for advanced glycation end products (RAGE) regulation of adiposity and adiponectin is associated with atherogenesis in apoE deficient mouse
-
20435311 1:CAS:528:DC%2BC3cXps1Cmu7s%3D 10.1016/j.atherosclerosis.2010. 04.006
-
H. Ueno, H. Koyama, T. Shoji, M. Monden, S. Fukumoto, S. Tanaka, Y. Otsuka, Y. Mima, T. Morioka, K. Mori, A. Shioi, H. Yamamoto, M. Inaba, Y. Nishizawa, Receptor for advanced glycation end products (RAGE) regulation of adiposity and adiponectin is associated with atherogenesis in apoE deficient mouse. Atherosclerosis 211(2), 431-436 (2010)
-
(2010)
Atherosclerosis
, vol.211
, Issue.2
, pp. 431-436
-
-
Ueno, H.1
Koyama, H.2
Shoji, T.3
Monden, M.4
Fukumoto, S.5
Tanaka, S.6
Otsuka, Y.7
Mima, Y.8
Morioka, T.9
Mori, K.10
Shioi, A.11
Yamamoto, H.12
Inaba, M.13
Nishizawa, Y.14
-
114
-
-
84857554882
-
RAGE influences obesity in mice. Effects of the presence of RAGE on weight gain, AGE accumulation, and insulin levels in mice on a high fat diet
-
22350391 1:STN:280:DC%2BC38vpsFKgsw%3D%3D 10.1007/s00391-011-0279-x
-
B. Leuner, M. Max, K. Thamm, C. Kausler, Y. Yakobus, A. Bierhaus, S. Sel, B. Hofmann, R. Silber, A. Simm, N. Nass, RAGE influences obesity in mice. Effects of the presence of RAGE on weight gain, AGE accumulation, and insulin levels in mice on a high fat diet. Z. Gerontol. Geriatr. 45(2), 102-108 (2012)
-
(2012)
Z. Gerontol. Geriatr.
, vol.45
, Issue.2
, pp. 102-108
-
-
Leuner, B.1
Max, M.2
Thamm, K.3
Kausler, C.4
Yakobus, Y.5
Bierhaus, A.6
Sel, S.7
Hofmann, B.8
Silber, R.9
Simm, A.10
Nass, N.11
-
115
-
-
0034804569
-
Glycated serum albumin-induced vascular smooth muscle cell proliferation through activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway by protein kinase C
-
11237743 1:CAS:528:DC%2BD3MXhs1Churs%3D 10.1006/bbrc.2001.4436
-
Y. Hattori, H. Kakishita, K. Akimoto, M. Matsumura, K. Kasai, Glycated serum albumin-induced vascular smooth muscle cell proliferation through activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway by protein kinase C. Biochem. Biophys. Res. Commun. 281(4), 891-896 (2001)
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.281
, Issue.4
, pp. 891-896
-
-
Hattori, Y.1
Kakishita, H.2
Akimoto, K.3
Matsumura, M.4
Kasai, K.5
-
116
-
-
4143087382
-
Advanced glycation endproduct (AGE) receptor 1 is a negative regulator of the inflammatory response to AGE in mesangial cells
-
15289604 1:CAS:528:DC%2BD2cXntVersrg%3D 10.1073/pnas.0401588101
-
C. Lu, J. He, W. Cai, H. Liu, L. Zhu, H. Vlassara, Advanced glycation endproduct (AGE) receptor 1 is a negative regulator of the inflammatory response to AGE in mesangial cells. Proc. Natl. Acad. Sci. USA 101(32), 11767-11772 (2004)
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, Issue.32
, pp. 11767-11772
-
-
Lu, C.1
He, J.2
Cai, W.3
Liu, H.4
Zhu, L.5
Vlassara, H.6
-
117
-
-
38349191034
-
AGE-receptor-1 counteracts cellular oxidant stress induced by AGEs via negative regulation of p66shc-dependent FKHRL1 phosphorylation
-
18032526 1:CAS:528:DC%2BD1cXhtVWktbY%3D 10.1152/ajpcell.00350.2007
-
W. Cai, J.C. He, L. Zhu, X. Chen, G. Striker, H. Vlassara, AGE-receptor-1 counteracts cellular oxidant stress induced by AGEs via negative regulation of p66shc-dependent FKHRL1 phosphorylation. Am. J. Physiol. Cell Physiol. 294(1), C145-C152 (2008)
-
(2008)
Am. J. Physiol. Cell Physiol.
, vol.294
, Issue.1
-
-
Cai, W.1
He, J.C.2
Zhu, L.3
Chen, X.4
Striker, G.5
Vlassara, H.6
-
118
-
-
77749264564
-
AGER1 regulates endothelial cell NADPH oxidase-dependent oxidant stress via PKC-delta: Implications for vascular disease
-
19955485 1:CAS:528:DC%2BC3cXjsFGhu7k%3D 10.1152/ajpcell.00463.2009
-
W. Cai, M. Torreggiani, L. Zhu, X. Chen, J. He, G. Striker, H. Vlassara, AGER1 regulates endothelial cell NADPH oxidase-dependent oxidant stress via PKC-delta: implications for vascular disease. Am. J. Physiol. Cell Physiol. 298(3), C624-C634 (2010)
-
(2010)
Am. J. Physiol. Cell Physiol.
, vol.298
, Issue.3
-
-
Cai, W.1
Torreggiani, M.2
Zhu, L.3
Chen, X.4
He, J.5
Striker, G.6
Vlassara, H.7
-
119
-
-
83055195095
-
Glucose and its metabolites have distinct effects on the calcium-induced mitochondrial permeability transition
-
J. Skrha Jr, J. Gáll, R. Buchal, E. Sedláč ková, J. Pláteník, Glucose and its metabolites have distinct effects on the calcium-induced mitochondrial permeability transition. Folia Biol. (Praha) 57(3), 96-103 (2011)
-
(2011)
Folia Biol. (Praha)
, vol.57
, Issue.3
, pp. 96-103
-
-
Skrha, Jr.J.1
Gáll, J.2
Buchal, R.3
Sedláčková, E.4
Pláteník, J.5
-
120
-
-
80053460459
-
Differential effects of insulin on peripheral diabetes-related changes in mitochondrial bioenergetics: Involvement of advanced glycosylated end products
-
21767639 1:CAS:528:DC%2BC3MXht1KmsbnK 10.1016/j.bbadis.2011.06.017
-
A. Remor, F. de Matos, K. Ghisoni, T. da Silva, G. Eidt, M. Búrigo, A. de Bem, P. Silveira, A. de León, M. Sanchez, A. Hohl, V. Glaser, C. Gonçalves, A. Quincozes-Santos, R. Borba Rosa, A. Latini, Differential effects of insulin on peripheral diabetes-related changes in mitochondrial bioenergetics: involvement of advanced glycosylated end products. Biochim. Biophys. Acta. 1812(11), 1460-1471 (2011)
-
(2011)
Biochim. Biophys. Acta.
, vol.1812
, Issue.11
, pp. 1460-1471
-
-
Remor, A.1
De Matos, F.2
Ghisoni, K.3
Da Silva, T.4
Eidt, G.5
Búrigo, M.6
De Bem, A.7
Silveira, P.8
De León, A.9
Sanchez, M.10
Hohl, A.11
Glaser, V.12
Gonçalves, C.13
Quincozes-Santos, A.14
Borba Rosa, R.15
Latini, A.16
-
121
-
-
12244312488
-
Methylglyoxal induces apoptosis through activation of p38 mitogen-activated protein kinase in rat mesangial cells
-
12631075 1:CAS:528:DC%2BD3sXivV2jsbo%3D 10.1046/j.1523-1755.2003.00829.x
-
B. Liu, S. Miyata, Y. Hirota, S. Higo, H. Miyazaki, M. Fukunaga, Y. Hamada, S. Ueyama, O. Muramoto, A. Uriuhara, M. Kasuga, Methylglyoxal induces apoptosis through activation of p38 mitogen-activated protein kinase in rat mesangial cells. Kidney Int. 63(3), 947-957 (2003)
-
(2003)
Kidney Int.
, vol.63
, Issue.3
, pp. 947-957
-
-
Liu, B.1
Miyata, S.2
Hirota, Y.3
Higo, S.4
Miyazaki, H.5
Fukunaga, M.6
Hamada, Y.7
Ueyama, S.8
Muramoto, O.9
Uriuhara, A.10
Kasuga, M.11
-
122
-
-
34447542039
-
Methylglyoxal-induced fibronectin gene expression through Ras-mediated NADPH oxidase activation in renal mesangial cells
-
1:CAS:528:DC%2BD2sXhtVShsbbL 10.1111/j.1440-1797.2007.00809.x
-
C. Ho, P. Lee, W. Huang, Y. Hsu, C. Lin, J. Wang, Methylglyoxal-induced fibronectin gene expression through Ras-mediated NADPH oxidase activation in renal mesangial cells. Nephrology (Carlton) 12(4), 348-356 (2007)
-
(2007)
Nephrology (Carlton)
, vol.12
, Issue.4
, pp. 348-356
-
-
Ho, C.1
Lee, P.2
Huang, W.3
Hsu, Y.4
Lin, C.5
Wang, J.6
-
123
-
-
77956174800
-
Cytotoxic role of methylglyoxal in rat retinal pericytes: Involvement of a nuclear factor-kappaB and inducible nitric oxide synthase pathway
-
20621070 1:CAS:528:DC%2BC3cXhtV2hsL3P 10.1016/j.cbi.2010.07.002
-
J. Kim, O. Kim, C. Kim, N. Kim, J. Kim, Cytotoxic role of methylglyoxal in rat retinal pericytes: involvement of a nuclear factor-kappaB and inducible nitric oxide synthase pathway. Chem. Biol. Interact. 188(1), 86-93 (2010)
-
(2010)
Chem. Biol. Interact.
, vol.188
, Issue.1
, pp. 86-93
-
-
Kim, J.1
Kim, O.2
Kim, C.3
Kim, N.4
Kim, J.5
-
124
-
-
38749130432
-
The tandem of free radicals and methylglyoxal
-
18164697 1:CAS:528:DC%2BD1cXhsVSiurs%3D 10.1016/j.cbi.2007.11.009
-
M. Kalapos, The tandem of free radicals and methylglyoxal. Chem. Biol. Interact. 171(3), 251-271 (2008)
-
(2008)
Chem. Biol. Interact.
, vol.171
, Issue.3
, pp. 251-271
-
-
Kalapos, M.1
-
125
-
-
0037446144
-
Involvement of MEKK1/ERK/P21Waf1/Cip1 signal transduction pathway in inhibition of IGF-I-mediated cell growth response by methylglyoxal
-
12647305 1:CAS:528:DC%2BD3sXislOntLo%3D 10.1002/jcb.10478
-
J. Du, S. Cai, H. Suzuki, A. Akhand, X. Ma, Y. Takagi, T. Miyata, I. Nakashima, F. Nagase, Involvement of MEKK1/ERK/P21Waf1/Cip1 signal transduction pathway in inhibition of IGF-I-mediated cell growth response by methylglyoxal. J. Cell. Biochem. 88(6), 1235-1246 (2003)
-
(2003)
J. Cell. Biochem.
, vol.88
, Issue.6
, pp. 1235-1246
-
-
Du, J.1
Cai, S.2
Suzuki, H.3
Akhand, A.4
Ma, X.5
Takagi, Y.6
Miyata, T.7
Nakashima, I.8
Nagase, F.9
-
126
-
-
53649101961
-
Modulation of insulin action by advanced glycation endproducts: A new player in the field
-
18792872 1:CAS:528:DC%2BD1cXhtlamtbzL 10.1055/s-0028-1082085
-
C. Schalkwijk, O. Brouwers, C. Stehouwer, Modulation of insulin action by advanced glycation endproducts: a new player in the field. Horm. Metab. Res. 40(9), 614-619 (2008)
-
(2008)
Horm. Metab. Res.
, vol.40
, Issue.9
, pp. 614-619
-
-
Schalkwijk, C.1
Brouwers, O.2
Stehouwer, C.3
-
127
-
-
33745312600
-
Methylglyoxal impairs the insulin signaling pathways independently of the formation of intracellular reactive oxygen species
-
16644685 1:CAS:528:DC%2BD28XksFaht7k%3D 10.2337/db05-0857
-
A. Riboulet-Chavey, A. Pierron, I. Durand, J. Murdaca, J. Giudicelli, E. Van Obberghen, Methylglyoxal impairs the insulin signaling pathways independently of the formation of intracellular reactive oxygen species. Diabetes 55(5), 1289-1299 (2006)
-
(2006)
Diabetes
, vol.55
, Issue.5
, pp. 1289-1299
-
-
Riboulet-Chavey, A.1
Pierron, A.2
Durand, I.3
Murdaca, J.4
Giudicelli, J.5
Van Obberghen, E.6
-
128
-
-
35548952654
-
Accumulation of endogenous methylglyoxal impaired insulin signaling in adipose tissue of fructose-fed rats
-
17660951 1:CAS:528:DC%2BD2sXhtFyru7vK 10.1007/s11010-007-9563-x
-
X. Jia, L. Wu, Accumulation of endogenous methylglyoxal impaired insulin signaling in adipose tissue of fructose-fed rats. Mol. Cell. Biochem. 306, 133-139 (2007)
-
(2007)
Mol. Cell. Biochem.
, vol.306
, pp. 133-139
-
-
Jia, X.1
Wu, L.2
-
129
-
-
79952403213
-
Chronic methylglyoxal infusion by minipump causes pancreatic beta-cell dysfunction and induces type 2 diabetes in Sprague-Dawley rats
-
21300844 1:CAS:528:DC%2BC3MXktVKktr8%3D 10.2337/db10-0627
-
A. Dhar, I. Dhar, B. Jiang, K. Desai, L. Wu, Chronic methylglyoxal infusion by minipump causes pancreatic beta-cell dysfunction and induces type 2 diabetes in Sprague-Dawley rats. Diabetes 60(3), 899-908 (2011)
-
(2011)
Diabetes
, vol.60
, Issue.3
, pp. 899-908
-
-
Dhar, A.1
Dhar, I.2
Jiang, B.3
Desai, K.4
Wu, L.5
-
130
-
-
68449092608
-
Methylglyoxal contributes to the development of insulin resistance and salt sensitivity in Sprague-Dawley rats
-
19531965 1:CAS:528:DC%2BD1MXoslOgt74%3D 10.1097/HJH.0b013e32832c419a
-
Q. Guo, T. Mori, Y. Jiang, C. Hu, Y. Osaki, Y. Yoneki, Y. Sun, T. Hosoya, A. Kawamata, S. Ogawa, M. Nakayama, T. Miyata, S. Ito, Methylglyoxal contributes to the development of insulin resistance and salt sensitivity in Sprague-Dawley rats. J. Hypertens. 27(8), 1664-1671 (2009)
-
(2009)
J. Hypertens.
, vol.27
, Issue.8
, pp. 1664-1671
-
-
Guo, Q.1
Mori, T.2
Jiang, Y.3
Hu, C.4
Osaki, Y.5
Yoneki, Y.6
Sun, Y.7
Hosoya, T.8
Kawamata, A.9
Ogawa, S.10
Nakayama, M.11
Miyata, T.12
Ito, S.13
-
131
-
-
0036300606
-
Improved insulin sensitivity is associated with restricted intake of dietary glycoxidation products in the db/db mouse
-
12086936 1:CAS:528:DC%2BD38Xlt1Wlt7w%3D 10.2337/diabetes.51.7.2082
-
S. Hofmann, H. Dong, Z. Li, W. Cai, J. Altomonte, S. Thung, F. Zeng, E. Fisher, H. Vlassara, Improved insulin sensitivity is associated with restricted intake of dietary glycoxidation products in the db/db mouse. Diabetes 51(7), 2082-2089 (2002)
-
(2002)
Diabetes
, vol.51
, Issue.7
, pp. 2082-2089
-
-
Hofmann, S.1
Dong, H.2
Li, Z.3
Cai, W.4
Altomonte, J.5
Thung, S.6
Zeng, F.7
Fisher, E.8
Vlassara, H.9
-
132
-
-
80054699727
-
Methylglyoxal impairs insulin signalling and insulin action on glucose-induced insulin secretion in the pancreatic beta cell line INS-1E
-
21861178 1:CAS:528:DC%2BC3MXht12js7bP 10.1007/s00125-011-2280-8
-
F. Fiory, A. Lombardi, C. Miele, J. Giudicelli, F. Beguinot, E. Van Obberghen, Methylglyoxal impairs insulin signalling and insulin action on glucose-induced insulin secretion in the pancreatic beta cell line INS-1E. Diabetologia 54(11), 2941-2952 (2011)
-
(2011)
Diabetologia
, vol.54
, Issue.11
, pp. 2941-2952
-
-
Fiory, F.1
Lombardi, A.2
Miele, C.3
Giudicelli, J.4
Beguinot, F.5
Van Obberghen, E.6
-
133
-
-
0032499396
-
Effects of methylglyoxal on rat pancreatic beta-cells
-
10076526 1:CAS:528:DyaK1cXislemsLY%3D 10.1016/S0006-2952(97)00619-9
-
L. Cook, J. Davies, A. Yates, A. Elliott, J. Lovell, J. Joule, P. Pemberton, P.J. Thornalley, L. Best, Effects of methylglyoxal on rat pancreatic beta-cells. Biochem. Pharmacol. 55(9), 1361-1367 (1998)
-
(1998)
Biochem. Pharmacol.
, vol.55
, Issue.9
, pp. 1361-1367
-
-
Cook, L.1
Davies, J.2
Yates, A.3
Elliott, A.4
Lovell, J.5
Joule, J.6
Pemberton, P.7
Thornalley, P.J.8
Best, L.9
-
134
-
-
0034659178
-
Glycoxidation and lipoxidation in atherogenesis
-
10946212 1:CAS:528:DC%2BD3cXls1Giu7k%3D 10.1016/S0891-5849(00)00228-8
-
J.W. Baynes, S. Thorpe, Glycoxidation and lipoxidation in atherogenesis. Free Radic. Biol. Med. 28, 1708-1716 (2000)
-
(2000)
Free Radic. Biol. Med.
, vol.28
, pp. 1708-1716
-
-
Baynes, J.W.1
Thorpe, S.2
-
135
-
-
34248162057
-
Methylglyoxal, oxidative stress, and hypertension
-
17487230 1:CAS:528:DC%2BD2sXktVSmsrw%3D 10.1139/y06-077
-
T. Chang, L. Wu, Methylglyoxal, oxidative stress, and hypertension. Can. J. Physiol. Pharmacol. 84, 1229-1238 (2006)
-
(2006)
Can. J. Physiol. Pharmacol.
, vol.84
, pp. 1229-1238
-
-
Chang, T.1
Wu, L.2
-
136
-
-
0031009347
-
Inactivation of glutathione reductase by 4-hydroxynonenal and other endogenous aldehydes
-
9175718 1:CAS:528:DyaK2sXjtFersrc%3D 10.1016/S0006-2952(97)00090-7
-
D. Vander Jagt, L. Hunsaker, T. Vander Jagt, M. Gomez, D. Gonzales, L. Deck, R. Royer, Inactivation of glutathione reductase by 4-hydroxynonenal and other endogenous aldehydes. Biochem. Pharmacol. 53, 1133-1140 (1997)
-
(1997)
Biochem. Pharmacol.
, vol.53
, pp. 1133-1140
-
-
Vander Jagt, D.1
Hunsaker, L.2
Vander Jagt, T.3
Gomez, M.4
Gonzales, D.5
Deck, L.6
Royer, R.7
-
137
-
-
0029613839
-
Methylglyoxal induces hprt mutation and DNA adducts in human T lymphocytes in vitro
-
8575417 1:CAS:528:DyaK28XjsFynsg%3D%3D 10.1002/em.2850260404
-
S. Hou, P. Nori, J. Fang, C. Vaca, Methylglyoxal induces hprt mutation and DNA adducts in human T lymphocytes in vitro. Environ. Mol. Mutagen. 26, 286-291 (1995)
-
(1995)
Environ. Mol. Mutagen.
, vol.26
, pp. 286-291
-
-
Hou, S.1
Nori, P.2
Fang, J.3
Vaca, C.4
-
138
-
-
0029933943
-
Effect of methylglyoxal on human leukaemia 60 cell growth: Modification of DNA G1 growth arrest and induction of apoptosis
-
8683979 1:CAS:528:DyaK28XkvFaht7k%3D 10.1016/0145-2126(95)00162-X
-
Y. Kang, L. Edwards, P.J. Thornalley, Effect of methylglyoxal on human leukaemia 60 cell growth: modification of DNA G1 growth arrest and induction of apoptosis. Leuk. Res. 20, 397-405 (1996)
-
(1996)
Leuk. Res.
, vol.20
, pp. 397-405
-
-
Kang, Y.1
Edwards, L.2
Thornalley, P.J.3
-
139
-
-
0035882511
-
Superoxide-mediated early oxidation and activation of ASK1 are important for initiating methylglyoxal-induced apoptosis process
-
11498280 1:CAS:528:DC%2BD3MXlslGntbg%3D 10.1016/S0891-5849(01)00611-6
-
J. Du, H. Suzuki, F. Nagase, A. Akhand, X. Ma, T. Yokoyama, T. Miyata, I. Nakashima, Superoxide-mediated early oxidation and activation of ASK1 are important for initiating methylglyoxal-induced apoptosis process. Free Radic. Biol. Med. 31, 469-478 (2001)
-
(2001)
Free Radic. Biol. Med.
, vol.31
, pp. 469-478
-
-
Du, J.1
Suzuki, H.2
Nagase, F.3
Akhand, A.4
Ma, X.5
Yokoyama, T.6
Miyata, T.7
Nakashima, I.8
-
140
-
-
0030570730
-
Induction of apoptotic cell death by methylglyoxal and 3-deoxyglucosone in macrophage-derived cell lines
-
8769121 1:CAS:528:DyaK28Xlslejsr8%3D 10.1006/bbrc.1996.1157
-
A. Okado, Y. Kawasaki, Y. Hasuike, M. Takahashi, T. Teshima, J. Fujii, N. Taniguchi, Induction of apoptotic cell death by methylglyoxal and 3-deoxyglucosone in macrophage-derived cell lines. Biochem. Biophys. Res. Commun. 225, 219-224 (1996)
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.225
, pp. 219-224
-
-
Okado, A.1
Kawasaki, Y.2
Hasuike, Y.3
Takahashi, M.4
Teshima, T.5
Fujii, J.6
Taniguchi, N.7
-
141
-
-
0033816515
-
The impaired renal vasodilator response attributed to endothelium-derived hyperpolarizing factor in streptozotocin-induced diabetic rats is restored by 5-methyltetrahydrofolate
-
11043857 10.1007/s001250051502
-
A. De Vriese, J. Van De Voorde, H. Blom, P. Vanhoutte, M. Verbeke, N. Lameire, The impaired renal vasodilator response attributed to endothelium-derived hyperpolarizing factor in streptozotocin-induced diabetic rats is restored by 5-methyltetrahydrofolate. Diabetologia 43, 1116-1125 (2000)
-
(2000)
Diabetologia
, vol.43
, pp. 1116-1125
-
-
De Vriese, A.1
Van De Voorde, J.2
Blom, H.3
Vanhoutte, P.4
Verbeke, M.5
Lameire, N.6
-
142
-
-
28944444040
-
Endothelial dysfunction in the streptozotocin-induced diabetic apoE deficient mouse
-
16231005 1:CAS:528:DC%2BD2MXht12ltrvL 10.1038/sj.bjp.0706417
-
H. Ding, M. Hashem, W. Wiehler, W. Lau, J. Martin, J. Reid, C. Triggle, Endothelial dysfunction in the streptozotocin-induced diabetic apoE deficient mouse. Br. J. Pharmacol. 146, 1110-1118 (2005)
-
(2005)
Br. J. Pharmacol.
, vol.146
, pp. 1110-1118
-
-
Ding, H.1
Hashem, M.2
Wiehler, W.3
Lau, W.4
Martin, J.5
Reid, J.6
Triggle, C.7
-
143
-
-
17844375947
-
Enhanced vascular reactivity of small mesenteric arteries from diabetic mice is associated with enhanced oxidative stress and cyclooxygenase products
-
15685205 1:CAS:528:DC%2BD2MXivVOisrY%3D 10.1038/sj.bjp.0706121
-
M. Pannirselvam, W. Wiehler, T. Anderson, C. Triggle, Enhanced vascular reactivity of small mesenteric arteries from diabetic mice is associated with enhanced oxidative stress and cyclooxygenase products. Br. J. Pharmacol. 144, 953-960 (2005)
-
(2005)
Br. J. Pharmacol.
, vol.144
, pp. 953-960
-
-
Pannirselvam, M.1
Wiehler, W.2
Anderson, T.3
Triggle, C.4
-
144
-
-
40149092820
-
Effects of alpha-lipoic acid on endothelial function in aged diabetic and high-fat fed rats
-
17906683 1:CAS:528:DC%2BD1cXislWisrg%3D 10.1038/sj.bjp.0707474
-
C. Sena, E. Nunes, T. Louro, T. Proença, R. Fernandes, M. Boarder, R. Seiça, Effects of alpha-lipoic acid on endothelial function in aged diabetic and high-fat fed rats. Br. J. Pharmacol. 153, 894-906 (2008)
-
(2008)
Br. J. Pharmacol.
, vol.153
, pp. 894-906
-
-
Sena, C.1
Nunes, E.2
Louro, T.3
Proença, T.4
Fernandes, R.5
Boarder, M.6
Seiça, R.7
-
145
-
-
80052096203
-
Glycation of LDL by methylglyoxal increases arterial atherogenicity: A possible contributor to increased risk of cardiovascular disease in diabetes
-
21617182 1:CAS:528:DC%2BC3MXptVChu74%3D 10.2337/db11-0085
-
N. Rabbani, L. Godfrey, M. Xue, F. Shaheen, M. Geoffrion, R. Milne, P.J. Thornalley, Glycation of LDL by methylglyoxal increases arterial atherogenicity: a possible contributor to increased risk of cardiovascular disease in diabetes. Diabetes 60(7), 1973-1980 (2011)
-
(2011)
Diabetes
, vol.60
, Issue.7
, pp. 1973-1980
-
-
Rabbani, N.1
Godfrey, L.2
Xue, M.3
Shaheen, F.4
Geoffrion, M.5
Milne, R.6
Thornalley, P.J.7
-
146
-
-
23744447530
-
Dicarbonyl intermediates in the Maillard reaction
-
16037229 1:CAS:528:DC%2BD2MXpvVKqs7c%3D 10.1196/annals.1333.014
-
P. Thornalley, Dicarbonyl intermediates in the Maillard reaction. Ann. N. Y. Acad. Sci. 1043, 111-117 (2005)
-
(2005)
Ann. N. Y. Acad. Sci.
, vol.1043
, pp. 111-117
-
-
Thornalley, P.1
-
147
-
-
77951183729
-
Increased glycation and oxidative damage to apolipoprotein B100 of LDL cholesterol in patients with type 2 diabetes and effect of metformin
-
20068133 1:CAS:528:DC%2BC3cXltFSmtLo%3D 10.2337/db09-1455
-
N. Rabbani, M. Chittari, C. Bodmer, D. Zehnder, A. Ceriello, P.J. Thornalley, Increased glycation and oxidative damage to apolipoprotein B100 of LDL cholesterol in patients with type 2 diabetes and effect of metformin. Diabetes 59, 1038-1045 (2010)
-
(2010)
Diabetes
, vol.59
, pp. 1038-1045
-
-
Rabbani, N.1
Chittari, M.2
Bodmer, C.3
Zehnder, D.4
Ceriello, A.5
Thornalley, P.J.6
-
148
-
-
0032939905
-
Metformin reduces systemic methylglyoxal levels in type 2 diabetes
-
9892243 1:CAS:528:DyaK1MXhvFSitg%3D%3D 10.2337/diabetes.48.1.198
-
P. Beisswenger, S.K. Howell, A. Touchette, S. Lal, B. Szwergold, Metformin reduces systemic methylglyoxal levels in type 2 diabetes. Diabetes 48, 198-202 (1999)
-
(1999)
Diabetes
, vol.48
, pp. 198-202
-
-
Beisswenger, P.1
Howell, S.K.2
Touchette, A.3
Lal, S.4
Szwergold, B.5
-
149
-
-
23344435471
-
Vascular methylglyoxal metabolism and the development of hypertension
-
16003184 1:CAS:528:DC%2BD2MXlvVymtLg%3D 10.1097/01.hjh.0000173778.85233. 1b
-
X. Wang, K. Desai, T. Chang, L. Wu, Vascular methylglyoxal metabolism and the development of hypertension. J. Hypertens. 23, 1565-1573 (2005)
-
(2005)
J. Hypertens.
, vol.23
, pp. 1565-1573
-
-
Wang, X.1
Desai, K.2
Chang, T.3
Wu, L.4
-
150
-
-
10644223132
-
Increased methylglyoxal and advanced glycation end products in kidney from spontaneously hypertensive rats
-
15569321 1:CAS:528:DC%2BD2MXisVOqug%3D%3D 10.1111/j.1523-1755.2004.66034. x
-
X. Wang, K. Desai, J. Clausen, L. Wu, Increased methylglyoxal and advanced glycation end products in kidney from spontaneously hypertensive rats. Kidney Int. 66, 2315-2321 (2004)
-
(2004)
Kidney Int.
, vol.66
, pp. 2315-2321
-
-
Wang, X.1
Desai, K.2
Clausen, J.3
Wu, L.4
-
151
-
-
40449113838
-
Attenuation of hypertension development by scavenging methylglyoxal in fructose-treated rats
-
18327087 1:CAS:528:DC%2BD1cXivFyjsrY%3D 10.1097/HJH.0b013e3282f4a13c
-
X. Wang, X. Jia, T. Chang, K. Desai, L. Wu, Attenuation of hypertension development by scavenging methylglyoxal in fructose-treated rats. J. Hypertens. 26, 765-772 (2008)
-
(2008)
J. Hypertens.
, vol.26
, pp. 765-772
-
-
Wang, X.1
Jia, X.2
Chang, T.3
Desai, K.4
Wu, L.5
-
152
-
-
77955981191
-
Methylglyoxal is a predictor in type 2 diabetic patients of intima-media thickening and elevation of blood pressure
-
20644005 1:CAS:528:DC%2BC3cXhtVCntrjK 10.1161/HYPERTENSIONAHA.110.156786
-
S. Ogawa, K. Nakayama, M. Nakayama, T. Mori, M. Matsushima, M. Okamura, M. Senda, K. Nako, T. Miyata, S. Ito, Methylglyoxal is a predictor in type 2 diabetic patients of intima-media thickening and elevation of blood pressure. Hypertension 56, 471-476 (2010)
-
(2010)
Hypertension
, vol.56
, pp. 471-476
-
-
Ogawa, S.1
Nakayama, K.2
Nakayama, M.3
Mori, T.4
Matsushima, M.5
Okamura, M.6
Senda, M.7
Nako, K.8
Miyata, T.9
Ito, S.10
-
153
-
-
84855887867
-
Serum concentration of an inflammatory glycotoxin, methylglyoxal, is associated with increased cognitive decline in elderly individuals
-
22079406 1:CAS:528:DC%2BC3MXhs1Cqt7bK 10.1016/j.mad.2011.10.007
-
M. Beeri, E. Moshier, J. Schmeidler, J. Godbold, J. Uribarri, S. Reddy, M. Sano, H. Grossman, W. Cai, H. Vlassara, J. Silverman, Serum concentration of an inflammatory glycotoxin, methylglyoxal, is associated with increased cognitive decline in elderly individuals. Mech. Ageing Dev. 132(11-12), 583-587 (2011)
-
(2011)
Mech. Ageing Dev.
, vol.132
, Issue.11-12
, pp. 583-587
-
-
Beeri, M.1
Moshier, E.2
Schmeidler, J.3
Godbold, J.4
Uribarri, J.5
Reddy, S.6
Sano, M.7
Grossman, H.8
Cai, W.9
Vlassara, H.10
Silverman, J.11
-
154
-
-
23744509806
-
Methylglyoxal induces apoptosis through oxidative stress-mediated activation of p38 mitogen-activated protein kinase in rat Schwann cells
-
16037234 1:CAS:528:DC%2BD2MXpvVKqsLo%3D 10.1196/annals.1333.019
-
M. Fukunaga, S. Miyata, S. Higo, Y. Hamada, S. Ueyama, M. Kasuga, Methylglyoxal induces apoptosis through oxidative stress-mediated activation of p38 mitogen-activated protein kinase in rat Schwann cells. Ann. N. Y. Acad. Sci. 1043, 151-157 (2005)
-
(2005)
Ann. N. Y. Acad. Sci.
, vol.1043
, pp. 151-157
-
-
Fukunaga, M.1
Miyata, S.2
Higo, S.3
Hamada, Y.4
Ueyama, S.5
Kasuga, M.6
-
155
-
-
21744448064
-
Methylglyoxal administration induces diabetes-like microvascular changes and perturbs the healing process of cutaneous wounds
-
1:CAS:528:DC%2BD2MXntlSnu7c%3D 10.1042/CS20050026
-
J. Berlanga, D. Cibrian, I. Guillén, F. Freyre, J. Alba, P. Lopez-Saura, N. Merino, A. Aldama, A. Quintela, M. Triana, J. Montequin, H. Ajamieh, D. Urquiza, N. Ahmed, P.J. Thornalley, Methylglyoxal administration induces diabetes-like microvascular changes and perturbs the healing process of cutaneous wounds. Clin. Sci. (Lond) 109(1), 83-95 (2005)
-
(2005)
Clin. Sci. (Lond)
, vol.109
, Issue.1
, pp. 83-95
-
-
Berlanga, J.1
Cibrian, D.2
Guillén, I.3
Freyre, F.4
Alba, J.5
Lopez-Saura, P.6
Merino, N.7
Aldama, A.8
Quintela, A.9
Triana, M.10
Montequin, J.11
Ajamieh, H.12
Urquiza, D.13
Ahmed, N.14
Thornalley, P.J.15
-
156
-
-
77954911547
-
Methylglyoxal increases cardiomyocyte ischemia-reperfusion injury via glycative inhibition of thioredoxin activity
-
20460580 1:CAS:528:DC%2BC3cXhtVOhtL%2FN
-
X. Wang, W. Lau, Y. Yuan, Y. Wang, W. Yi, T. Christopher, B. Lopez, H. Liu, X. Ma, Methylglyoxal increases cardiomyocyte ischemia-reperfusion injury via glycative inhibition of thioredoxin activity. Am. J. Physiol. Endocrinol. Metab. 299(2), E207-E214 (2010)
-
(2010)
Am. J. Physiol. Endocrinol. Metab.
, vol.299
, Issue.2
-
-
Wang, X.1
Lau, W.2
Yuan, Y.3
Wang, Y.4
Yi, W.5
Christopher, T.6
Lopez, B.7
Liu, H.8
Ma, X.9
-
157
-
-
67349101253
-
Angiogenesis, adipokines and breast cancer
-
19520599 1:CAS:528:DC%2BD1MXnsFaitL8%3D 10.1016/j.cytogfr.2009.05.007
-
L. Vona-Davis, D. Rose, Angiogenesis, adipokines and breast cancer. Cytokine Growth Factor Rev. 20, 193-201 (2009)
-
(2009)
Cytokine Growth Factor Rev.
, vol.20
, pp. 193-201
-
-
Vona-Davis, L.1
Rose, D.2
-
158
-
-
36248956180
-
Effects of advanced glycation end product modification on proximal tubule epithelial cell processing of albumin
-
17890854 1:CAS:528:DC%2BD2sXhsVCnurzJ 10.1159/000108757
-
A. Ozdemir, U. Hopfer, M. Rosca, X. Fan, V. Monnier, M. Weiss, Effects of advanced glycation end product modification on proximal tubule epithelial cell processing of albumin. Am. J. Nephrol. 28(1), 14-24 (2008)
-
(2008)
Am. J. Nephrol.
, vol.28
, Issue.1
, pp. 14-24
-
-
Ozdemir, A.1
Hopfer, U.2
Rosca, M.3
Fan, X.4
Monnier, V.5
Weiss, M.6
-
159
-
-
80052091211
-
Advanced glycation urinary protein-bound biomarkers and severity of diabetic nephropathy in man
-
21876347 1:CAS:528:DC%2BC3MXhtlKrsrrK 10.1159/000331064
-
M. Coughlan, S. Patel, G. Jerums, S. Penfold, T. Nguyen, K. Sourris, S. Panagiotopoulos, P. Srivastava, M. Cooper, L. Burrell, R. Macisaac, J. Forbes, Advanced glycation urinary protein-bound biomarkers and severity of diabetic nephropathy in man. Am. J. Nephrol. 34(4), 347-355 (2011)
-
(2011)
Am. J. Nephrol.
, vol.34
, Issue.4
, pp. 347-355
-
-
Coughlan, M.1
Patel, S.2
Jerums, G.3
Penfold, S.4
Nguyen, T.5
Sourris, K.6
Panagiotopoulos, S.7
Srivastava, P.8
Cooper, M.9
Burrell, L.10
MacIsaac, R.11
Forbes, J.12
-
160
-
-
0021715307
-
Structural-functional relationships in diabetic nephropathy
-
6480821 1:STN:280:DyaL2M%2FgslCgsg%3D%3D 10.1172/JCI111523
-
S. Mauer, M. Steffes, E. Ellis, D. Sutherland, D. Brown, F. Goetz, Structural-functional relationships in diabetic nephropathy. J. Clin. Invest. 74, 1143-1155 (1984)
-
(1984)
J. Clin. Invest.
, vol.74
, pp. 1143-1155
-
-
Mauer, S.1
Steffes, M.2
Ellis, E.3
Sutherland, D.4
Brown, D.5
Goetz, F.6
-
161
-
-
34547614831
-
Plasma protein advanced glycation end products, carboxymethyl cysteine, and carboxyethyl cysteine, are elevated and related to nephropathy in patients with diabetes
-
17318407 1:CAS:528:DC%2BD2sXotVKqu7w%3D 10.1007/s11010-007-9422-9
-
A. Mostafa, E. Randell, S. Vasdev, V. Gill, Y. Han, V. Gadag, A. Raouf, H. El Said, Plasma protein advanced glycation end products, carboxymethyl cysteine, and carboxyethyl cysteine, are elevated and related to nephropathy in patients with diabetes. Mol. Cell. Biochem. 302(1-2), 35-42 (2007)
-
(2007)
Mol. Cell. Biochem.
, vol.302
, Issue.1-2
, pp. 35-42
-
-
Mostafa, A.1
Randell, E.2
Vasdev, S.3
Gill, V.4
Han, Y.5
Gadag, V.6
Raouf, A.7
El Said, H.8
-
162
-
-
79959797020
-
Targeted reduction of advanced glycation improves renal function in obesity
-
21412218 1:CAS:528:DC%2BC3MXotlers74%3D 10.1038/ki.2011.57
-
B. Harcourt, K. Sourris, M. Coughlan, K. Walker, S. Dougherty, S. Andrikopoulos, A. Morley, V. Thallas-Bonke, V. Chand, S. Penfold, M. de Courten, M.C. Thomas, B.A. Kingwell, A. Bierhaus, M.E. Cooper, B. Courten, J.M. Forbes, Targeted reduction of advanced glycation improves renal function in obesity. Kidney Int. 80(2), 190-198 (2011)
-
(2011)
Kidney Int.
, vol.80
, Issue.2
, pp. 190-198
-
-
Harcourt, B.1
Sourris, K.2
Coughlan, M.3
Walker, K.4
Dougherty, S.5
Andrikopoulos, S.6
Morley, A.7
Thallas-Bonke, V.8
Chand, V.9
Penfold, S.10
De Courten, M.11
Thomas, M.C.12
Kingwell, B.A.13
Bierhaus, A.14
Cooper, M.E.15
Courten, B.16
Forbes, J.M.17
-
163
-
-
79955420320
-
Differential effects of advanced glycation end-products on renal tubular cell inflammation
-
1:CAS:528:DC%2BC3MXnsl2isbw%3D 10.1111/j.1440-1797.2010.01437.x
-
S. Tang, L. Chan, J. Leung, A. Cheng, M. Lin, H. Lan, K. Lai, Differential effects of advanced glycation end-products on renal tubular cell inflammation. Nephrology (Carlton). 16(4), 417-425 (2011)
-
(2011)
Nephrology (Carlton).
, vol.16
, Issue.4
, pp. 417-425
-
-
Tang, S.1
Chan, L.2
Leung, J.3
Cheng, A.4
Lin, M.5
Lan, H.6
Lai, K.7
-
164
-
-
22344442393
-
Glycation of mitochondrial proteins from diabetic rat kidney is associated with excess superoxide formation
-
15814529 1:CAS:528:DC%2BD2MXotFeju78%3D 10.1152/ajprenal.00415.2004
-
M. Rosca, T. Mustata, M. Kinter, A. Ozdemir, T. Kern, L. Szweda, M. Brownlee, V. Monnier, M. Weiss, Glycation of mitochondrial proteins from diabetic rat kidney is associated with excess superoxide formation. Am. J. Physiol. Renal. Physiol. 289, F420-F430 (2005)
-
(2005)
Am. J. Physiol. Renal. Physiol.
, vol.289
-
-
Rosca, M.1
Mustata, T.2
Kinter, M.3
Ozdemir, A.4
Kern, T.5
Szweda, L.6
Brownlee, M.7
Monnier, V.8
Weiss, M.9
-
165
-
-
80053510114
-
NF-κB-inducing kinase increases renal tubule epithelial inflammation associated with diabetes
-
21869881 10.1155/2011/192564 1:CAS:528:DC%2BC3MXht1Ciu7bM
-
Y. Zhao, S. Banerjee, W. LeJeune, S. Choudhary, R. Tilton, NF-κB-inducing kinase increases renal tubule epithelial inflammation associated with diabetes. Exp. Diabetes Res. 2011, 192564 (2011)
-
(2011)
Exp. Diabetes Res.
, vol.2011
, pp. 192564
-
-
Zhao, Y.1
Banerjee, S.2
Lejeune, W.3
Choudhary, S.4
Tilton, R.5
-
166
-
-
84855185323
-
Targeted proteomics of isolated glomeruli from the kidneys of diabetic rats: Sorbin and SH3 domain containing 2 is a novel protein associated with diabetic nephropathy
-
22007191 10.1155/2011/979354 1:CAS:528:DC%2BC3MXhsVWju7nF
-
S. Nakatani, A. Kakehashi, E. Ishimura, S. Yamano, K. Mori, M. Wei, M. Inaba, H. Wanibuchi, Targeted proteomics of isolated glomeruli from the kidneys of diabetic rats: sorbin and SH3 domain containing 2 is a novel protein associated with diabetic nephropathy. Exp. Diabetes Res. 2011, 979354 (2011)
-
(2011)
Exp. Diabetes Res.
, vol.2011
, pp. 979354
-
-
Nakatani, S.1
Kakehashi, A.2
Ishimura, E.3
Yamano, S.4
Mori, K.5
Wei, M.6
Inaba, M.7
Wanibuchi, H.8
-
167
-
-
80053052721
-
Podocytopathy in diabetes: A metabolic and endocrine disorder
-
21719174 10.1053/j.ajkd.2011.03.035
-
A. Diez-Sampedro, O. Lenz, A. Fornoni, Podocytopathy in diabetes: a metabolic and endocrine disorder. Am. J. Kidney Dis. 58(4), 637-646 (2011)
-
(2011)
Am. J. Kidney Dis.
, vol.58
, Issue.4
, pp. 637-646
-
-
Diez-Sampedro, A.1
Lenz, O.2
Fornoni, A.3
-
168
-
-
70350511901
-
Increased retinopathy occurrence in type 1 diabetes patients with increased serum levels of the advanced glycation endproduct hydroimidazolone
-
18631328 1:CAS:528:DC%2BD1MXhtFWis7vF 10.1111/j.1755-3768.2008.01300.x
-
D. Fosmark, J. Berg, A. Jensen, L. Sandvik, E. Agardh, C. Agardh, K. Hanssen. Increased retinopathy occurrence in type 1 diabetes patients with increased serum levels of the advanced glycation endproduct hydroimidazolone. Acta Ophthalmol. 87(5), 498-500 (2009)
-
(2009)
Acta Ophthalmol.
, vol.87
, Issue.5
, pp. 498-500
-
-
Fosmark, D.1
Berg, J.2
Jensen, A.3
Sandvik, L.4
Agardh, E.5
Agardh, C.6
Hanssen, K.7
-
169
-
-
80052678727
-
Accumulation of renin and imidazolone in peritubular capillary endothelial cells in insulin-resistant hypertensive rats
-
21484732 1:CAS:528:DC%2BC3MXhsVOrsLfE 10.5301/JN.2011.6520
-
Z. Wagner, P. Degrell, B. Lukáts, T. Niwa, G. Molnár, L. Markó, Z. Karádi, I. Wittmann, Accumulation of renin and imidazolone in peritubular capillary endothelial cells in insulin-resistant hypertensive rats. J. Nephrol. 24(5), 656-664 (2011)
-
(2011)
J. Nephrol.
, vol.24
, Issue.5
, pp. 656-664
-
-
Wagner, Z.1
Degrell, P.2
Lukáts, B.3
Niwa, T.4
Molnár, G.5
Markó, L.6
Karádi, Z.7
Wittmann, I.8
-
170
-
-
33644659446
-
Gender-related differences in advanced glycation endproducts, oxidative stress markers and nitric oxide synthases in rats
-
16408117 1:CAS:528:DC%2BD28XksVKrug%3D%3D 10.1038/sj.ki.5000043
-
X. Wang, K. Desai, B. Juurlink, J. de Champlain, L. Wu, Gender-related differences in advanced glycation endproducts, oxidative stress markers and nitric oxide synthases in rats. Kidney Int. 69(2), 281-287 (2006)
-
(2006)
Kidney Int.
, vol.69
, Issue.2
, pp. 281-287
-
-
Wang, X.1
Desai, K.2
Juurlink, B.3
De Champlain, J.4
Wu, L.5
-
171
-
-
77955375901
-
Deletion of the receptor for advanced Glycation end products reduces glomerulosclerosis and preserves renal function in the diabetic OVE26 mouse
-
20627935 1:CAS:528:DC%2BC3cXhtVOlsbjJ 10.2337/db09-1766
-
N. Reiniger, K. Lau, D. McCalla, B. Eby, B. Cheng, Y. Lu, W. Qu, N. Quadri, R. Ananthakrishnan, M. Furmansky, R. Rosario, F. Song, V. Rai, A. Weinberg, R. Friedman, R. Ramasamy, V. D'Agati, A. Schmidt, Deletion of the receptor for advanced Glycation end products reduces glomerulosclerosis and preserves renal function in the diabetic OVE26 mouse. Diabetes 59, 2043-2054 (2010)
-
(2010)
Diabetes
, vol.59
, pp. 2043-2054
-
-
Reiniger, N.1
Lau, K.2
McCalla, D.3
Eby, B.4
Cheng, B.5
Lu, Y.6
Qu, W.7
Quadri, N.8
Ananthakrishnan, R.9
Furmansky, M.10
Rosario, R.11
Song, F.12
Rai, V.13
Weinberg, A.14
Friedman, R.15
Ramasamy, R.16
D'Agati, V.17
Schmidt, A.18
-
172
-
-
70350511901
-
Increased retinopathy occurrence in type 1 diabetes patients with increased serum levels of the advanced glycation endproduct hydroimidazolone
-
18631328 1:CAS:528:DC%2BD1MXhtFWis7vF 10.1111/j.1755-3768.2008.01300.x
-
D. Fosmark, J. Berg, A. Jensen, L. Sandvik, E. Agardh, C. Agardh, K. Hanssen, Increased retinopathy occurrence in type 1 diabetes patients with increased serum levels of the advanced glycation endproduct hydroimidazolone. Acta Ophthalmol. 87(5), 498-500 (2009)
-
(2009)
Acta Ophthalmol.
, vol.87
, Issue.5
, pp. 498-500
-
-
Fosmark, D.1
Berg, J.2
Jensen, A.3
Sandvik, L.4
Agardh, E.5
Agardh, C.6
Hanssen, K.7
-
173
-
-
77953330776
-
KIOM-79 prevents methyglyoxal-induced retinal pericyte apoptosis in vitro and in vivo
-
20362656 10.1016/j.jep.2010.03.027
-
O. Kim, J. Kim, C. Kim, N. Kim, J. Kim, KIOM-79 prevents methyglyoxal-induced retinal pericyte apoptosis in vitro and in vivo. J. Ethnopharmacol. 129(3), 285-292 (2010)
-
(2010)
J. Ethnopharmacol.
, vol.129
, Issue.3
, pp. 285-292
-
-
Kim, O.1
Kim, J.2
Kim, C.3
Kim, N.4
Kim, J.5
-
174
-
-
1542333426
-
Methylglyoxal induces apoptosis mediated by reactive oxygen species in bovine retinal pericytes
-
14966349 1:CAS:528:DC%2BD2cXis1Sgs7s%3D 10.3346/jkms.2004.19.1.95
-
J. Kim, J. Son, J. Lee, Y. Oh, S. Shinn, Methylglyoxal induces apoptosis mediated by reactive oxygen species in bovine retinal pericytes. J. Korean Med. Sci. 19(1), 95-100 (2004)
-
(2004)
J. Korean Med. Sci.
, vol.19
, Issue.1
, pp. 95-100
-
-
Kim, J.1
Son, J.2
Lee, J.3
Oh, Y.4
Shinn, S.5
-
175
-
-
84878249875
-
Advanced glycation end products and diabetic retinopathy
-
Epub Ahead of Print
-
R. Milne, S. Brownstein. Advanced glycation end products and diabetic retinopathy. Amino Acids (2011) [Epub Ahead of Print]
-
(2011)
Amino Acids
-
-
Milne, R.1
Brownstein, S.2
-
176
-
-
84862903126
-
Methylglyoxal induces hyperpermeability of the bloodretinal barrier via the loss of tight junction proteins and the activation of matrix metalloproteinases
-
22249316 1:CAS:528:DC%2BC38XmtFehs7s%3D 10.1007/s00417-011-1912-5
-
J. Kim, C. Kim, Y. Lee, K. Jo, S. Shin, J. Kim, Methylglyoxal induces hyperpermeability of the bloodretinal barrier via the loss of tight junction proteins and the activation of matrix metalloproteinases. Graefes Arch. Clin. Exp. Ophthalmol. 250(5), 691-697 (2012)
-
(2012)
Graefes Arch. Clin. Exp. Ophthalmol.
, vol.250
, Issue.5
, pp. 691-697
-
-
Kim, J.1
Kim, C.2
Lee, Y.3
Jo, K.4
Shin, S.5
Kim, J.6
-
177
-
-
78651410794
-
Overexpression of glyoxalase-I reduces hyperglycemia-induced levels of advanced glycation endproducts and oxidative stress in diabetic rats
-
21056979 1:CAS:528:DC%2BC3MXjtFehsA%3D%3D 10.1074/jbc.M110.144097
-
O. Brouwers, P. Niessen, I. Ferreira, T. Miyata, P. Scheffer, T. Teerlink, P. Schrauwen, M. Brownlee, C. Stehouwer, C. Schalkwijk, Overexpression of glyoxalase-I reduces hyperglycemia-induced levels of advanced glycation endproducts and oxidative stress in diabetic rats. J. Biol. Chem. 286(2), 1374-1380 (2011)
-
(2011)
J. Biol. Chem.
, vol.286
, Issue.2
, pp. 1374-1380
-
-
Brouwers, O.1
Niessen, P.2
Ferreira, I.3
Miyata, T.4
Scheffer, P.5
Teerlink, T.6
Schrauwen, P.7
Brownlee, M.8
Stehouwer, C.9
Schalkwijk, C.10
-
178
-
-
53549084867
-
Aminoacetone, a putative endogenous source of methylglyoxal, causes oxidative stress and death in insulin-producing RINm5f cells
-
18729331 1:CAS:528:DC%2BD1cXhtVaru7fJ 10.1021/tx8001753
-
A. Sartori, H. Garay-Malpartida, M. Forni, R. Schumacher, F. Dutra, M. Sogayar, E. Bechara, Aminoacetone, a putative endogenous source of methylglyoxal, causes oxidative stress and death in insulin-producing RINm5f cells. Chem. Res. Toxicol. 21(9), 1841-1850 (2008)
-
(2008)
Chem. Res. Toxicol.
, vol.21
, Issue.9
, pp. 1841-1850
-
-
Sartori, A.1
Garay-Malpartida, H.2
Forni, M.3
Schumacher, R.4
Dutra, F.5
Sogayar, M.6
Bechara, E.7
-
179
-
-
33845916839
-
Methylglyoxal in food and living organisms
-
17103372 1:CAS:528:DC%2BD2sXmsFegtw%3D%3D 10.1002/mnfr.200600065
-
I. Nemet, L. Varga-Defterdarović, Z. Turk, Methylglyoxal in food and living organisms. Mol. Nutr. Food Res. 50(12), 1105-1117 (2006)
-
(2006)
Mol. Nutr. Food Res.
, vol.50
, Issue.12
, pp. 1105-1117
-
-
Nemet, I.1
Varga-Defterdarović, L.2
Turk, Z.3
-
180
-
-
84860648993
-
Postprandial impairment of flow-mediated dilation and elevated methylglyoxal after simple but not complex carbohydrate consumption in dogs
-
22575041 1:CAS:528:DC%2BC38XmtlWkurk%3D 10.1016/j.nutres.2012.03.002
-
J. Adolphe, M. Drew, Q. Huang, T. Silver, L. Weber, Postprandial impairment of flow-mediated dilation and elevated methylglyoxal after simple but not complex carbohydrate consumption in dogs. Nutr. Res. 32(4), 278-284 (2012)
-
(2012)
Nutr. Res.
, vol.32
, Issue.4
, pp. 278-284
-
-
Adolphe, J.1
Drew, M.2
Huang, Q.3
Silver, T.4
Weber, L.5
-
181
-
-
0034820785
-
Alpha-Dicarbonyls increase in the postprandial period and reflect the degree of hyperglycemia
-
11315838 1:CAS:528:DC%2BD3MXivVOmurs%3D 10.2337/diacare.24.4.726
-
P.J. Beisswenger, S.K. Howell, R.M. O'Dell, M.E. Wood, A.D. Touchette, B.S. Szwergold, alpha-Dicarbonyls increase in the postprandial period and reflect the degree of hyperglycemia. Diabetes Care 24(4), 726-732 (2001)
-
(2001)
Diabetes Care
, vol.24
, Issue.4
, pp. 726-732
-
-
Beisswenger, P.J.1
Howell, S.K.2
O'Dell, R.M.3
Wood, M.E.4
Touchette, A.D.5
Szwergold, B.S.6
-
182
-
-
78650044928
-
Candesartan attenuates diabetic retinal vascular pathology by restoring glyoxalase-I function
-
20852029 1:CAS:528:DC%2BC3MXlsVaksQ%3D%3D 10.2337/db10-0552
-
A.G. Miller, G. Tan, K.J. Binger, R.J. Pickering, M.C. Thomas, R.H. Nagaraj, M.E. Cooper, J.L. Wilkinson-Berka, Candesartan attenuates diabetic retinal vascular pathology by restoring glyoxalase-I function. Diabetes 59(12), 3208-3215 (2010)
-
(2010)
Diabetes
, vol.59
, Issue.12
, pp. 3208-3215
-
-
Miller, A.G.1
Tan, G.2
Binger, K.J.3
Pickering, R.J.4
Thomas, M.C.5
Nagaraj, R.H.6
Cooper, M.E.7
Wilkinson-Berka, J.L.8
-
183
-
-
79955825348
-
Advanced glycation end product recognition by the receptor for AGEs
-
21565706 1:CAS:528:DC%2BC3MXmtFGhs7w%3D 10.1016/j.str.2011.02.013
-
J. Xue, V. Rai, D. Singer, S. Chabierski, J. Xie, S. Reverdatto, D.S. Burz, A.M. Schmidt, R. Hoffmann, A. Shekhtman, Advanced glycation end product recognition by the receptor for AGEs. Structure 19(5), 722-732 (2011)
-
(2011)
Structure
, vol.19
, Issue.5
, pp. 722-732
-
-
Xue, J.1
Rai, V.2
Singer, D.3
Chabierski, S.4
Xie, J.5
Reverdatto, S.6
Burz, D.S.7
Schmidt, A.M.8
Hoffmann, R.9
Shekhtman, A.10
-
184
-
-
84255163024
-
Receptor for AGE (RAGE): Signaling mechanisms in the pathogenesis of diabetes and its complications
-
22211895 1:CAS:528:DC%2BC38XivVynsLY%3D 10.1111/j.1749-6632.2011.06320.x
-
R. Ramasamy, S. Yan, A. Schmidt, Receptor for AGE (RAGE): signaling mechanisms in the pathogenesis of diabetes and its complications. Ann. N. Y. Acad. Sci. 1243, 88-102 (2011)
-
(2011)
Ann. N. Y. Acad. Sci.
, vol.1243
, pp. 88-102
-
-
Ramasamy, R.1
Yan, S.2
Schmidt, A.3
|