Long-term methylglyoxal treatment impairs smooth muscle contractility in organ-cultured rat mesenteric artery

Pharmacological Research

Volumn 65, Issue 1, 2012, Pages 91-99

  Mukohda, Masashi ^a   Morita, Tomoka ^a   Okada, Muneyoshi ^a   Hara, Yukio ^a   Yamawaki, Hideyuki ^a  

^a KITASATO UNIVERSITY   (Japan)

Author keywords

Contraction; Glucose metabolite; Organ culture; Reactive oxygen species; Vascular smooth muscle

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; EXTRACELLULAR SUPEROXIDE DISMUTASE; MANGANESE SUPEROXIDE DISMUTASE; METHYLGLYOXAL; OXIDOREDUCTASE; P22PHOX PROTEIN; P47PHOX PROTEIN; P67PHOX PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTERY CONSTRICTION; ARTICLE; CONTROLLED STUDY; HYPERTENSION; MALE; MESENTERIC ARTERY; NONHUMAN; PATHOLOGICAL ANATOMY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SMOOTH MUSCLE CONTRACTILITY; TISSUE CULTURE; WESTERN BLOTTING;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; MALE; MESENTERIC ARTERIES; MUSCLE, SMOOTH, VASCULAR; NADH, NADPH OXIDOREDUCTASES; NF-KAPPA B; ORGAN CULTURE TECHNIQUES; PYRUVALDEHYDE; RATS; RATS, WISTAR; SUPEROXIDE DISMUTASE; SUPEROXIDES; TIME FACTORS; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS;

EID: 84855988671     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2011.08.005     Document Type: Article

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