Methylglyoxal induces prostaglandin E2 production in rat mesangial cells

Kobe Journal of Medical Sciences

Volumn 53, Issue 6, 2007, Pages 305-315

  Uriuhara, Atsuko ^a   Miyata, Satoshi ^a   Liu, Bing Fen ^a   Miyazaki, Hiroyuki ^a   Kusunoki, Hitomi ^a   Kojima, Hiroshi ^a   Yamashita, Yumiko ^a   Suzuki, Kotaro ^a   Inaba, Kayo ^a   Kasuga, Masato ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Cyclooxygenase 2; Diabetic nephropathy; Glycation; MAP kinase

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CARBONYL DERIVATIVE; CYCLOOXYGENASE 2; METHYLGLYOXAL; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; PROSTAGLANDIN E2;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DIABETIC NEPHROPATHY; DISEASE COURSE; ENZYME ACTIVATION; ENZYME IMMUNOASSAY; ENZYME SYNTHESIS; GLYCATION; HYPERGLYCEMIA; INCUBATION TIME; MALE; MESANGIUM CELL; NONHUMAN; NORTHERN BLOTTING; PROSTAGLANDIN RELEASE; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; RAT;

ANIMALS; CELLS, CULTURED; CYCLOOXYGENASE 2; DINOPROSTONE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; MALE; MESANGIAL CELLS; MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN KINASE INHIBITORS; PYRUVALDEHYDE; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER;

EID: 45749127330     PISSN: 00232513     EISSN: 18830498     Source Type: Journal    
DOI: None     Document Type: Article

References (53)

1. Barnett, R., Scharschmidt, L., Ko, Y.H., and Schlondorff, D. 1987. Comparison of glomerular and mesangial prostaglandin synthesis and glomerular contraction in two rat models of diabetes mellitus. Diabetes 36:1468-1475.
2. Beisswenger, P.J., Howell, S.K., O'Dell, R.M., Wood, M.E., Touchette, A.D., and Szwergold, B.S. 2001. α-Dicarbonyls increase in the postprandial period and reflect the degree of hyperglycemia. Diabetes Care 24:726-732.
3. Brenner, B.M., Cooper, M.E., de Zeeuw, D., Keane, W.F., Mitch, W.E., Parving, H.H., Remuzzi, G., Snapinn, S.M., Zhang, Z., and Shahinfar, S. 2001. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N. Engl. J. Med. 345:861-869.
4. Breyer, M.D., Davis, L., Jacobson, H.R., and Breyer, R.M. 1996. Differential localization of prostaglandin E receptor subtypes in human kidney. Am. J. Physiol. Renal Physiol. 270:F912-F918.
5. Breyer, M.D., and Breyer, R.M. 2000. Prostaglandin E receptors and the kidney. Am. J. Physiol. Renal Physiol. 279:F12-F23.
6. Brownlee, M. 2001. Biochemistry and molecular cell biology of diabetic complications. Nature 414:813-820.
7. Chang, T., Wang, R., and Wu, L. 2005. Methylglyoxal-induced nitric oxide and peroxynitrite production in vascular smooth muscle cells. Free Radic. Biol. Med. 38:286-293.
8. Che, W., Asahi, M., Takahashi, M., Kaneto, H., Okado, A., Higashiyama, S., and Taniguchi, N. 1997. Selective induction of heparin-binding epidermal growth factor-like growth factor by methylglyoxal and 3-deoxyglucosone in rat aortic smooth muscle cells. The involvement of reactive oxygen species formation and a possible implication for atherogenesis in diabetes. J. Biol. Chem. 272:18453-18459.
9. Craven, P.A., Caines, M.A., and DeRubertis, F.R. 1987. Sequential alterations in glomerular prostaglandin and thromboxane synthesis in diabetic rats: relationship to the hyperfiltration of early diabetes. Metabolism 36:95-103.
10. DeRubertis, F.R., and Craven, P.A. 1993. Eicosanoids in the pathogenesis of the functional and structural alterations of the kidney in diabetes. Am. J. Kidney Dis. 22:727-735.
11. Esmatjes, E., Fernandez, M.R., Halperin, I., Camps, J., Gaya, J., Arroyo, V., Rivera, F., and Figuerola, D. 1985. Renal hemodynamic abnormalities in patients with short term insulin-dependent diabetes mellitus: role of renal prostaglandins. J. Clin. Endocrinol. Metab. 60:1231-1236.
12. Frye, E.B., Degenhardt ,T.P., Thorpe, S.R., and Baynes, J.W. 1998. Role of the Maillard reaction in aging of tissue proteins. Advanced glycation end product-dependent increase in imidazolium cross-links in human lens proteins. J. Biol. Chem. 273:18714-18719.
13. Fukunaga, M., Miyata, S., Liu, B.F., Miyazaki, H., Hirota, Y., Higo, S., Hamada, Y., Ueyama, S., and Kasuga, M. 2004. Methylglyoxal Induces Apoptosis through Activation of p38 MAPK in Rat Schwann Cells. Biochem. Biophys. Res. Commun. 320:689-695.
14. Gambardella, S., Andreani, D., Cancelli, A., Di Mario, U., Cardamone, I., Stirati, G., Cinotti, G.A., and Pugliese, F. 1988. Renal hemodynamics and urinary excretion of 6-keto-prostaglandin F1 alpha and thromboxane B2 in newly diagnosed type 1 diabetic patients. Diabetes 37:1044-1048.
15. Guan, Z., Buckman, S.Y., Baier, L.D., and Morrison, A.R. 1998. IGF-I and insulin amplify IL-1 beta-induced nitric oxide and prostaglandin biosynthesis. Am. J. Physiol. Renal Physiol. 274:F673-F679.
16. Guo, Y.S., Hellmich, M.R., Wen, X.D., and Townsend, C.M. Jr. 2001. Activator protein-1 transcription factor mediates bombesin-stimulated cyclooxygenase-2 expression in intestinal epithelial cells. J. Biol. Chem. 276:22941-22947.
17. Hayase, F., Nagaraj, R.H., Miyata, S., Njoroge, F.G., and Monnier, V.M. 1989. Aging of proteins: immunological detection of a glucose-derived pyrrole formed during Maillard reaction in vivo. J. Biol. Chem. 264:3758-3764.
18. Hommel, E., Mathiesen, E., Arnold-Larsen, S., Edsberg, B., Olsen, U.B., and Parving, H.H. 1987. Effects of indomethacin on kidney function in type 1 (insulin-dependent) diabetic patients with nephropathy. Diabetologia 30:78-81.
19. Horie, K., Miyata, T., Maeda, K., Miyata, S., Sugiyama, S., Sakai, H., van Ypersole de Strihou, C., Monnier, V.M., Witztum, J.L., and Kurokawa, K. 1997. Immunohistochemical colocalization of glycoxidation products and lipid peroxidation products in diabetic renal glomerular lesions. Implication for glycoxidative stress in the pathogenesis of diabetic nephropathy. J. Clin. Invest. 100:2995-3004.
20. Hostetter, T.H. 2001. Hypertrophy and hyperfunction of the diabetic kidney. J. Clin. Invest. 107:161-162.
21. Jensen, B.L., Schmid, C., and Kurtz, A. 1996. Prostaglandins stimulate renin secretion and renin mRNA in mouse renal juxtaglomerular cells. Am. J. Physiol. Renal Physiol. 271:F659-F669.
22. Kasiske, B.L., O'Donnell, M.P., and Keane, W.F. 1985. Glucose-induced increases in renal hemodynamic function. Possible modulation by renal prostaglandins. Diabetes 34:360-364.
23. Kiritoshi, S., Nishikawa, T., Sonoda, K., Kukidome, D., Senokuchi, T., Matsuo, T., Matsumura, T., Tokunaga, H., Brownlee, M., and Araki, E. 2003. Reactive oxygen species from mitochondria induce cyclooxygenase-2 gene expression in human mesangial cells: potential role in diabetic nephropathy. Diabetes 52:2570-2577.
24. Komers, R., Lindsley, J.N., Oyama, T.T., Schutzer, W.E., Reed, J.F., Mader, S.L., and Anderson, S. 2001. Immunohistochemical and functional correlations of renal cyclooxygenase-2 in experimental diabetes. J. Clin. Invest. 107:889-898.
25. Kreisberg, J.I., and Karnovsky, M.J. 1983. Glomerular cells in culture. Kidney Int. 23:439-447.
26. Kusunoki, H., Miyata, S., Ohara, T., Liu, B.F., Uriuhara, A., Kojima, H., Suzuki, K., Miyazaki, H., Yamashita, Y., Inaba, K., and Kasuga, M. 2003. Relation between serum 3-deoxyglucosone and development of diabetic microangiopathy. Diabetes Care 26:1889-1894.
27. LaPointe, M.C., and Isenovic, E. 1999. Interleukin-1 beta regulation of inducible nitric oxide synthase and cyclooxygenase-2 involves the p42/44 and p38 MAPK signaling pathways in cardiac myocytes. Hypertension 33:276-282.
28. Lapolla, A., Flamini, R., Dalla, V.A., Senesi, A., Reitano, R., Fedele, D., Basso, E., Seraglia, R., and Traldi, P. 2003. Glyoxal and methylglyoxal levels in diabetic patients: quantitative determination by a new GC/MS method. Clin. Chem. Lab. Med. 41:1166-1173.
29. Lasa, M., Mahtani, K.R., Finch, A., Brewer, G., Saklatvala, J., and Clark, A.R. 2000. Regulation of cyclooxygenase 2 mRNA stability by the mitogen-activated protein kinase p38 signaling cascade. Mol. Cell. Biol. 20:4265-4274.
30. Lewis, E.J., Hunsicker, L.G., Clarke, W.R., Berl, T., Pohl, M.A., Lewis, J.B., Ritz, E., Atkins, R.C., Rohde, R., and Raz, I. 2001. Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N. Engl. J. Med. 345:851-860.
31. Liu, B.F., Miyata, S., Hirota, Y., Higo, S., Miyazaki, H., Fukunaga, M., Hamada, Y., Ueyama, S., Muramoto, O., Uriuhara, A., and Kasuga, M. 2003. Methylglyoxal induces apoptosis through activation of p38 mitogen-activated protein kinase in rat mesangial cells. Kidney Int. 63:947-957.
32. Lukiw, W.J., Pelaez, R.P., Martinez, J., and Bazan, N.G. 1998. Budesonide epimer R or dexamethasone selectively inhibit platelet-activating factor-induced or interleukin 1β-induced DNA binding activity of cis-acting transcription factors and cyclooxygenase-2 gene expression in human epidermal keratinocytes. Proc. Natl. Acad. Sci. U. S. A. 95:3914-3919.
33. Makino, H., Tanaka, I., Mukoyama, M., Sugawara, A., Mori, K., Muro, S., Suganami, T., Yahata, K., Ishibashi, R., Ohuchida, S., Maruyama, T., Narumiya, S., and Nakao, K. 2002. Prevention of diabetic nephropathy in rats by prostaglandin E receptor EP1-selective antagonist. J. Am. Soc. Nephrol. 13:1757-1765.
34. Matsuura, H., Sakaue, M., Subbaramaiah, K., Kamitani, H., Eling, T.E., Dannenberg, A.J., Tanabe, T., Inoue, H., Arata, J., and Jetten, A.M. 1999. Regulation of cyclooxygenase-2 by interferon γ and transforming growth factor α in normal human epidermal keratinocytes and squamous carcinoma cells. Role of mitogen-activated protein kinases. J. Biol. Chem. 274:29138-29148.
35. McLellan, A.C., Thornalley, P.J., Benn, J., and Sonksen, P.H. 1994. Glyoxalase system in clinical diabetes mellitus and correlation with diabetic complications. Clin. Sci. (Lond.) 87:21-29.
36. Misko, T.P., Moore, W.M., Kasten, T.P., Nickols, G.A., Corbett, J.A., Tilton, R.G., McDaniel, M.L., Williamson, J.R., and Currie, M.G. 1993. Selective inhibition of the inducible nitric oxide synthase by aminoguanidine. Eur. J. Pharmacol. 233:119-125.
37. Mitchell, J.A., Kohlhaas, K.L., Sorrentino, R., Warner, T.D., Murad, F., and Vane, J.R. 1993. Induction by endotoxin of nitric oxide synthase in the rat mesentery: lack of effect on action of vasoconstrictors. Br. J. Pharmacol. 109:265-270.
38. Miyata, S., and Monnier, V. 1992. Immunohistochemical detection of advanced glycosylation end products in diabetic tissues using monoclonal antibody to pyrraline. J. Clin. Invest. 89:1102-1112.
39. O'Bryan, G.T., and Hostetter, T.H. 1997. The renal hemodynamic basis of diabetic nephropathy. Semin. Nephrol. 17:93-100.
40. Ohnaka, K., Numaguchi, K., Yamakawa, T., and Inagami, T. 2000. Induction of cyclooxygenase-2 by angiotensin II in cultured rat vascular smooth muscle cells. Hypertension 35:68-75.
41. Oya, T., Hattori, N., Mizuno, Y., Miyata, S., Maeda, S., Osawa, T., and Uchida, K. 1999. Methylglyoxal modification of protein. Chemical and immunochemical characterization of methylglyoxal-arginine adducts. J. Biol. Chem. 274:18492-18502.
42. Phillips, S.A., Mirrlees, D., and Thornalley, P.J. 1993. Modification of the glyoxalase system in streptozotocin-induced diabetic rat. Effect of the aldose reductase inhibitor Statil. Biochem. Pharmacol. 46: 805-811.
43. Phillips, S.A., and Thornalley, P.J. 1993. The formation of methylglyoxal from triose phosphates. Investigation using a specific assay for methylglyoxal. Eur. J. Biochem. 212:101-105.
44. Riboulet-Chavey, A., Pierron, A., Durand, I., Murdaca, J., Giudicelli, J.V., and Obberghen, E. 2006. Methylglyoxal impairs the insulin signaling pathways independently of the formation of intracellular reactive oxygen species. Diabetes 55:1289-1299.
45. Salvemini, D., Seibert, K., Masferrer, J.L., Misko, T.P., Currie, M.G., and Needleman, P. 1994. Endogenous nitric oxide enhances prostaglandin production in a model of renal inflammation. J. Clin. Invest. 93:1940-1947.
46. Shinohara, M., Thornalley, P.J., Giardino, I., Beisswenger, P., Thorpe, S.R., Onorato, J., and Brownlee, M. 1998. Overexpression of glyoxalase-I in bovine endothelial cells inhibits intracellular advanced glycation endproduct formation and prevents hyperglycemia-induced increases in macromolecular endocytosis. J. Clin. Invest. 101:1142-1147.
47. Shipanova, I.N., Glomb, M.A., and Nagaraj, R.H. 1997. Protein modification by methylglyoxal: chemical nature and synthetic mechanism of a major fluorescent adduct. Arch. Biochem. Biophys. 344:29-36.
48. Sugimoto, Y., Namba, T., Shigemoto, R., Negishi, M., Ichikawa, A., and Narumiya, S. 1994. Distinct cellular localization of mRNAs for three subtypes of prostaglandin E receptor in kidney. Am. J. Physiol. Renal Physiol. 266:F823-F828.
49. Thornalley, P.J. 1993. The glyoxalase system in health and disease. Mol. Aspects Med. 14:287-371.
50. Thornalley, P.J., Yurek-George, A., and Argirov, O.K. 2000. Kinetics and mechanism of the reaction of aminoguanidine with the alpha-oxoaldehydes glyoxal, methylglyoxal, and 3-deoxyglucosone under physiological conditions. Biochem. Pharmacol. 60:55-65.
51. Viberti, G.C., Benigni, A., Bognetti, E., Remuzzi, G., and Wiseman, M.J. 1989. Glomerular hyperfiltration and urinary prostaglandins in type 1 diabetes mellitus. Diabet. Med. 6:219-223.
52. Wolff, D.J., and Lubeskie, A. 1995. Aminoguanidine is an isoform-selective, mechanism-based inactivator of nitric oxide synthase. Arch. Biochem. Biophys. 316:290-301.
53. Yamada, H., Miyata, S., Igaki, N., Yatabe, H., Miyauchi, Y., Ohara, T., Sakai, M., Shoda, H., Oimomi, M., and Kasuga, M. 1994. Increase in 3-deoxyglucosone levels in diabetic rat plasma. Specific in vivo determination of intermediate in advanced Maillard reaction. J. Biol. Chem. 269:20275-20280.