Eicosapentaenoic acid restores diabetic tubular injury through regulating oxidative stress and mitochondrial apoptosis

American Journal of Physiology - Renal Physiology

Volumn 299, Issue 6, 2010, Pages

  Taneda, Sekiko ^a   Honda, Kazuho ^a   Tomidokoro, Kimiko ^a   Uto, Kenta ^a   Nitta, Kosaku ^a   Oda, Hideaki ^a  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

Author keywords

Diabetic nephropathy; HIF 1 ; Hypoxia; Renal tubules; ROS; Streptozotocin

Indexed keywords

4 HYDROXYNONENAL; 8 HYDROXYDEOXYGUANOSINE; CASPASE 3; CASPASE 9; CYTOCHROME C; HUMALIN N; HYPOXIA INDUCIBLE FACTOR 1ALPHA; ICOSAPENTAENOIC ACID; INSULIN; METHYLGLYOXAL; N ACETYL BETA GLUCOSAMINIDASE; REACTIVE OXYGEN METABOLITE; STAUROSPORINE; UNCLASSIFIED DRUG;

ALBUMINURIA; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DIABETES MELLITUS; DIABETIC NEPHROPATHY; DIETARY INTAKE; DNA DAMAGE; FEMALE; FLOW CYTOMETRY; GLUCOSE BLOOD LEVEL; HISTOPATHOLOGY; HYPERGLYCEMIA; HYPOXIA; IMMUNOHISTOCHEMISTRY; KIDNEY TUBULE; KIDNEY TUBULE CELL; KIDNEY TUBULE DAMAGE; LIPID PEROXIDATION; MITOCHONDRION; MOUSE; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; STATISTICAL SIGNIFICANCE; STREPTOZOCIN DIABETES; UPREGULATION; URINALYSIS; URINE VOLUME; WESTERN BLOTTING;

EID: 78649965876     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00637.2009     Document Type: Article

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