Human aldo-keto reductase AKR7A2 protects against the cytotoxicity and mutagenicity of reactive aldehydes and lowers intracellular reactive oxygen species in hamster V79-4 cells

Chemico-Biological Interactions

Volumn 195, Issue 1, 2012, Pages 25-34

  Li, Dan ^a,b   Ferrari, Michele ^a   Ellis, Elizabeth M ^a  

^a UNIVERSITY OF STRATHCLYDE   (United Kingdom)

^b CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Aldehydes; Aldo keto reductase; Menadione; Oxidative stress

Indexed keywords

4 HYDROXYNONENAL; ACROLEIN; ALDEHYDE; ALDO KETO REDUCTASE 7A2; CROTONALDEHYDE; GLUTATHIONE; MENADIONE; METHYLGLYOXAL; MUCONALDEHYDE; OXIDOREDUCTASE; REACTIVE OXYGEN METABOLITE; SUCCINIC SEMIALDEHYDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL PROTECTION; CELL STRAIN; CONTROLLED STUDY; CYTOTOXICITY; DETOXIFICATION; DNA DAMAGE; GENOTOXICITY; HAMSTER; MUTAGENICITY; MUTATION RATE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION;

ACROLEIN; ALDEHYDE REDUCTASE; ALDEHYDES; ANIMALS; CASPASE 3; CELL LINE; CRICETINAE; DNA DAMAGE; GLUTATHIONE; HUMANS; MUTAGENICITY TESTS; OXIDATIVE STRESS; PYRUVALDEHYDE; REACTIVE OXYGEN SPECIES;

CRICETINAE; MAMMALIA;

EID: 82055200076     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2011.09.007     Document Type: Article

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