-
2
-
-
0029896530
-
Role of leptin in the neuroendocrine response to fasting
-
Ahima R.S., Prabakaran D., Mantzoros C., Qu D., Lowell B., Maratos-Flier E., Flier J.S. Role of leptin in the neuroendocrine response to fasting. Nature 1996, 382:250-252.
-
(1996)
Nature
, vol.382
, pp. 250-252
-
-
Ahima, R.S.1
Prabakaran, D.2
Mantzoros, C.3
Qu, D.4
Lowell, B.5
Maratos-Flier, E.6
Flier, J.S.7
-
3
-
-
0347854376
-
Regulation of C. elegans longevity by specific gustatory and olfactory neurons
-
Alcedo J., Kenyon C. Regulation of C. elegans longevity by specific gustatory and olfactory neurons. Neuron 2004, 41:45-55.
-
(2004)
Neuron
, vol.41
, pp. 45-55
-
-
Alcedo, J.1
Kenyon, C.2
-
4
-
-
52449135100
-
In vitro cellular adaptations of indicators of longevity in response to treatment with serum collected from humans on calorie restricted diets
-
Allard J.S., Heilbronn L.K., Smith C., Hunt N.D., Ingram D.K., Ravussin E., de Cabo R. In vitro cellular adaptations of indicators of longevity in response to treatment with serum collected from humans on calorie restricted diets. PLoS One 2008, 3:e3211.
-
(2008)
PLoS One
, vol.3
-
-
Allard, J.S.1
Heilbronn, L.K.2
Smith, C.3
Hunt, N.D.4
Ingram, D.K.5
Ravussin, E.6
de Cabo, R.7
-
5
-
-
78650168845
-
The vagus nerve as a regulator of growth hormone secretion
-
Al-Massadi O., Trujillo M.L., Senaris R., Pardo M., Castelao C., Casanueva F.F., Seoane L.M. The vagus nerve as a regulator of growth hormone secretion. Regul. Pept. 2011, 166:3-8.
-
(2011)
Regul. Pept.
, vol.166
, pp. 3-8
-
-
Al-Massadi, O.1
Trujillo, M.L.2
Senaris, R.3
Pardo, M.4
Castelao, C.5
Casanueva, F.F.6
Seoane, L.M.7
-
6
-
-
1642357670
-
Growth hormone secretion: molecular and cellular mechanisms and in vivo approaches
-
Anderson L.L., Jeftinija S., Scanes C.G. Growth hormone secretion: molecular and cellular mechanisms and in vivo approaches. Exp. Biol. Med. (Maywood) 2004, 229:291-302.
-
(2004)
Exp. Biol. Med. (Maywood)
, vol.229
, pp. 291-302
-
-
Anderson, L.L.1
Jeftinija, S.2
Scanes, C.G.3
-
7
-
-
83755165458
-
Rapamycin increases lifespan and inhibits spontaneous tumorigenesis in inbred female mice
-
Anisimov V.N., Zabezhinski M.A., Popovich I.G., Piskunova T.S., Semenchenko A.V., Tyndyk M.L., Yurova M.N., Rosenfeld S.V., Blagosklonny M.V. Rapamycin increases lifespan and inhibits spontaneous tumorigenesis in inbred female mice. Cell Cycle 2011, 10:4230-4236.
-
(2011)
Cell Cycle
, vol.10
, pp. 4230-4236
-
-
Anisimov, V.N.1
Zabezhinski, M.A.2
Popovich, I.G.3
Piskunova, T.S.4
Semenchenko, A.V.5
Tyndyk, M.L.6
Yurova, M.N.7
Rosenfeld, S.V.8
Blagosklonny, M.V.9
-
8
-
-
77957253419
-
Obesity and shift work: chronobiological aspects
-
Antunes L.C., Levandovski R., Dantas G., Caumo W., Hidalgo M.P. Obesity and shift work: chronobiological aspects. Nutr. Res. Rev. 2010, 23:155-168.
-
(2010)
Nutr. Res. Rev.
, vol.23
, pp. 155-168
-
-
Antunes, L.C.1
Levandovski, R.2
Dantas, G.3
Caumo, W.4
Hidalgo, M.P.5
-
9
-
-
0033576579
-
Regulation of lifespan by sensory perception in Caenorhabditis elegans
-
Apfeld J., Kenyon C. Regulation of lifespan by sensory perception in Caenorhabditis elegans. Nature 1999, 402:804-809.
-
(1999)
Nature
, vol.402
, pp. 804-809
-
-
Apfeld, J.1
Kenyon, C.2
-
11
-
-
84874066514
-
Molecules affecting hypothalamic control of core body temperature in response to calorie intake
-
Bartfai T., Conti B. Molecules affecting hypothalamic control of core body temperature in response to calorie intake. Front. Genet. 2012, 3:184.
-
(2012)
Front. Genet.
, vol.3
, pp. 184
-
-
Bartfai, T.1
Conti, B.2
-
12
-
-
64949184038
-
Biological approaches to mechanistically understand the healthy life span extension achieved by calorie restriction and modulation of hormones
-
Barzilai N., Bartke A. Biological approaches to mechanistically understand the healthy life span extension achieved by calorie restriction and modulation of hormones. J. Gerontol. A: Biol. Sci. Med. Sci. 2009, 64:187-191.
-
(2009)
J. Gerontol. A: Biol. Sci. Med. Sci.
, vol.64
, pp. 187-191
-
-
Barzilai, N.1
Bartke, A.2
-
13
-
-
53249134458
-
Role of the GH/IGF-1 axis in lifespan and healthspan: lessons from animal models
-
Berryman D.E., Christiansen J.S., Johannsson G., Thorner M.O., Kopchick J.J. Role of the GH/IGF-1 axis in lifespan and healthspan: lessons from animal models. Growth Horm. IGF Res. 2008, 18:455-471.
-
(2008)
Growth Horm. IGF Res.
, vol.18
, pp. 455-471
-
-
Berryman, D.E.1
Christiansen, J.S.2
Johannsson, G.3
Thorner, M.O.4
Kopchick, J.J.5
-
14
-
-
34249891333
-
Two neurons mediate diet-restriction-induced longevity in C. elegans
-
Bishop N.A., Guarente L. Two neurons mediate diet-restriction-induced longevity in C. elegans. Nature 2007, 447:545-549.
-
(2007)
Nature
, vol.447
, pp. 545-549
-
-
Bishop, N.A.1
Guarente, L.2
-
15
-
-
56449115916
-
Mediobasal hypothalamic p70 S6 kinase 1 modulates the control of energy homeostasis
-
Blouet C., Ono H., Schwartz G.J. Mediobasal hypothalamic p70 S6 kinase 1 modulates the control of energy homeostasis. Cell Metab. 2008, 8:459-467.
-
(2008)
Cell Metab.
, vol.8
, pp. 459-467
-
-
Blouet, C.1
Ono, H.2
Schwartz, G.J.3
-
16
-
-
0028296222
-
Ventromedial hypothalamic lesions in rats suppress counterregulatory responses to hypoglycemia
-
Borg W.P., During M.J., Sherwin R.S., Borg M.A., Brines M.L., Shulman G.I. Ventromedial hypothalamic lesions in rats suppress counterregulatory responses to hypoglycemia. J. Clin. Invest. 1994, 93:1677-1682.
-
(1994)
J. Clin. Invest.
, vol.93
, pp. 1677-1682
-
-
Borg, W.P.1
During, M.J.2
Sherwin, R.S.3
Borg, M.A.4
Brines, M.L.5
Shulman, G.I.6
-
17
-
-
0028931891
-
Local ventromedial hypothalamus glucopenia triggers counterregulatory hormone release
-
Borg W.P., Sherwin R.S., During M.J., Borg M.A., Shulman G.I. Local ventromedial hypothalamus glucopenia triggers counterregulatory hormone release. Diabetes 1995, 44:180-184.
-
(1995)
Diabetes
, vol.44
, pp. 180-184
-
-
Borg, W.P.1
Sherwin, R.S.2
During, M.J.3
Borg, M.A.4
Shulman, G.I.5
-
18
-
-
0031038124
-
Local ventromedial hypothalamus glucose perfusion blocks counterregulation during systemic hypoglycemia in awake rats
-
Borg M.A., Sherwin R.S., Borg W.P., Tamborlane W.V., Shulman G.I. Local ventromedial hypothalamus glucose perfusion blocks counterregulation during systemic hypoglycemia in awake rats. J. Clin. Invest. 1997, 99:361-365.
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 361-365
-
-
Borg, M.A.1
Sherwin, R.S.2
Borg, W.P.3
Tamborlane, W.V.4
Shulman, G.I.5
-
19
-
-
0345700729
-
Local lactate perfusion of the ventromedial hypothalamus suppresses hypoglycemic counterregulation
-
Borg M.A., Tamborlane W.V., Shulman G.I., Sherwin R.S. Local lactate perfusion of the ventromedial hypothalamus suppresses hypoglycemic counterregulation. Diabetes 2003, 52:663-666.
-
(2003)
Diabetes
, vol.52
, pp. 663-666
-
-
Borg, M.A.1
Tamborlane, W.V.2
Shulman, G.I.3
Sherwin, R.S.4
-
20
-
-
0031014810
-
Effects of 2-deoxy-d-glucose and insulin on plasma glucose levels and behavioral thermoregulation of toads
-
Branco L.G. Effects of 2-deoxy-d-glucose and insulin on plasma glucose levels and behavioral thermoregulation of toads. Am. J. Physiol. 1997, 272:R1-R5.
-
(1997)
Am. J. Physiol.
, vol.272
-
-
Branco, L.G.1
-
21
-
-
0019497652
-
Hypothalamic obesity. The autonomic hypothesis and the lateral hypothalamus
-
Bray G.A., Inoue S., Nishizawa Y. Hypothalamic obesity. The autonomic hypothesis and the lateral hypothalamus. Diabetologia 1981, 20:366-377.
-
(1981)
Diabetologia
, vol.20
, pp. 366-377
-
-
Bray, G.A.1
Inoue, S.2
Nishizawa, Y.3
-
22
-
-
0031023373
-
Effects of food deprivation on the GH axis: immunocytochemical and molecular analysis
-
Brogan R.S., Fife S.K., Conley L.K., Giustina A., Wehrenberg W.B. Effects of food deprivation on the GH axis: immunocytochemical and molecular analysis. Neuroendocrinology 1997, 65:129-135.
-
(1997)
Neuroendocrinology
, vol.65
, pp. 129-135
-
-
Brogan, R.S.1
Fife, S.K.2
Conley, L.K.3
Giustina, A.4
Wehrenberg, W.B.5
-
23
-
-
36849073063
-
Low utilization of circulating glucose after food withdrawal in snell dwarf mice
-
Brooks N.L., Trent C.M., Raetzsch C.F., Flurkey K., Boysen G., Perfetti M.T., Jeong Y.C., Klebanov S., Patel K.B., Khodush V.R., Kupper L.L., Carling D., Swenberg J.A., Harrison D.E., Combs T.P. Low utilization of circulating glucose after food withdrawal in snell dwarf mice. J. Biol. Chem. 2007, 282:35069-35077.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 35069-35077
-
-
Brooks, N.L.1
Trent, C.M.2
Raetzsch, C.F.3
Flurkey, K.4
Boysen, G.5
Perfetti, M.T.6
Jeong, Y.C.7
Klebanov, S.8
Patel, K.B.9
Khodush, V.R.10
Kupper, L.L.11
Carling, D.12
Swenberg, J.A.13
Harrison, D.E.14
Combs, T.P.15
-
24
-
-
20044393471
-
Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands
-
Broughton S.J., Piper M.D., Ikeya T., Bass T.M., Jacobson J., Driege Y., Martinez P., Hafen E., Withers D.J., Leevers S.J., Partridge L. Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands. Proc. Natl. Acad. Sci. USA 2005, 102:3105-3110.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 3105-3110
-
-
Broughton, S.J.1
Piper, M.D.2
Ikeya, T.3
Bass, T.M.4
Jacobson, J.5
Driege, Y.6
Martinez, P.7
Hafen, E.8
Withers, D.J.9
Leevers, S.J.10
Partridge, L.11
-
25
-
-
77956692450
-
DILP-producing median neurosecretory cells in the Drosophila brain mediate the response of lifespan to nutrition
-
Broughton S.J., Slack C., Alic N., Metaxakis A., Bass T.M., Driege Y., Partridge L. DILP-producing median neurosecretory cells in the Drosophila brain mediate the response of lifespan to nutrition. Aging Cell 2010, 9:336-346.
-
(2010)
Aging Cell
, vol.9
, pp. 336-346
-
-
Broughton, S.J.1
Slack, C.2
Alic, N.3
Metaxakis, A.4
Bass, T.M.5
Driege, Y.6
Partridge, L.7
-
26
-
-
0035856980
-
Biochemistry and molecular cell biology of diabetic complications
-
Brownlee M. Biochemistry and molecular cell biology of diabetic complications. Nature 2001, 414:813-820.
-
(2001)
Nature
, vol.414
, pp. 813-820
-
-
Brownlee, M.1
-
27
-
-
0032925851
-
Food restriction reduces brain damage and improves behavioral outcome following excitotoxic and metabolic insults
-
Bruce-Keller A.J., Umberger G., McFall R., Mattson M.P. Food restriction reduces brain damage and improves behavioral outcome following excitotoxic and metabolic insults. Ann. Neurol. 1999, 45:8-15.
-
(1999)
Ann. Neurol.
, vol.45
, pp. 8-15
-
-
Bruce-Keller, A.J.1
Umberger, G.2
McFall, R.3
Mattson, M.P.4
-
28
-
-
73649120921
-
Calorie restriction increases fatty acid synthesis and whole body fat oxidation rates
-
Bruss M.D., Khambatta C.F., Ruby M.A., Aggarwal I., Hellerstein M.K. Calorie restriction increases fatty acid synthesis and whole body fat oxidation rates. Am. J. Physiol. Endocrinol. Metab. 2010, 298:E108-E116.
-
(2010)
Am. J. Physiol. Endocrinol. Metab.
, vol.298
-
-
Bruss, M.D.1
Khambatta, C.F.2
Ruby, M.A.3
Aggarwal, I.4
Hellerstein, M.K.5
-
29
-
-
84856468940
-
Metabolic dysfunction in Alzheimer's disease and related neurodegenerative disorders
-
Cai H., Cong W.N., Ji S., Rothman S., Maudsley S., Martin B. Metabolic dysfunction in Alzheimer's disease and related neurodegenerative disorders. Curr. Alzheimer Res. 2012, 9:5-17.
-
(2012)
Curr. Alzheimer Res.
, vol.9
, pp. 5-17
-
-
Cai, H.1
Cong, W.N.2
Ji, S.3
Rothman, S.4
Maudsley, S.5
Martin, B.6
-
30
-
-
77949506721
-
Hypothalamic Sirt1 regulates food intake in a rodent model system
-
Cakir I., Perello M., Lansari O., Messier N.J., Vaslet C.A., Nillni E.A. Hypothalamic Sirt1 regulates food intake in a rodent model system. PLoS One 2009, 4:e8322.
-
(2009)
PLoS One
, vol.4
-
-
Cakir, I.1
Perello, M.2
Lansari, O.3
Messier, N.J.4
Vaslet, C.A.5
Nillni, E.A.6
-
31
-
-
0033615225
-
Role of nitric oxide in 2-deoxy-d-glucose-induced hypothermia in rats
-
Carnio E.C., Almeida M.C., Fabris G., Branco L.G. Role of nitric oxide in 2-deoxy-d-glucose-induced hypothermia in rats. Neuroreport 1999, 10:3101-3104.
-
(1999)
Neuroreport
, vol.10
, pp. 3101-3104
-
-
Carnio, E.C.1
Almeida, M.C.2
Fabris, G.3
Branco, L.G.4
-
32
-
-
78650245846
-
Caloric restriction and longevity: effects of reduced body temperature
-
Carrillo A.E., Flouris A.D. Caloric restriction and longevity: effects of reduced body temperature. Ageing Res. Rev. 2011, 10:153-162.
-
(2011)
Ageing Res. Rev.
, vol.10
, pp. 153-162
-
-
Carrillo, A.E.1
Flouris, A.D.2
-
33
-
-
34548860424
-
Brain fatty acid synthase activates PPARalpha to maintain energy homeostasis
-
Chakravarthy M.V., Zhu Y., Lopez M., Yin L., Wozniak D.F., Coleman T., Hu Z., Wolfgang M., Vidal-Puig A., Lane M.D., Semenkovich C.F. Brain fatty acid synthase activates PPARalpha to maintain energy homeostasis. J. Clin. Invest. 2007, 117:2539-2552.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 2539-2552
-
-
Chakravarthy, M.V.1
Zhu, Y.2
Lopez, M.3
Yin, L.4
Wozniak, D.F.5
Coleman, T.6
Hu, Z.7
Wolfgang, M.8
Vidal-Puig, A.9
Lane, M.D.10
Semenkovich, C.F.11
-
34
-
-
84859977895
-
Sirtuins mediate mammalian metabolic responses to nutrient availability
-
Chalkiadaki A., Guarente L. Sirtuins mediate mammalian metabolic responses to nutrient availability. Nat. Rev. Endocrinol. 2012, 8:287-296.
-
(2012)
Nat. Rev. Endocrinol.
, vol.8
, pp. 287-296
-
-
Chalkiadaki, A.1
Guarente, L.2
-
35
-
-
77952487491
-
Interactions between light, mealtime and calorie restriction to control daily timing in mammals
-
Challet E. Interactions between light, mealtime and calorie restriction to control daily timing in mammals. J. Comp. Physiol. B 2010, 180:631-644.
-
(2010)
J. Comp. Physiol. B
, vol.180
, pp. 631-644
-
-
Challet, E.1
-
36
-
-
34047114378
-
ATP-sensitive K(+) channels regulate the release of GABA in the ventromedial hypothalamus during hypoglycemia
-
Chan O., Lawson M., Zhu W., Beverly J.L., Sherwin R.S. ATP-sensitive K(+) channels regulate the release of GABA in the ventromedial hypothalamus during hypoglycemia. Diabetes 2007, 56:1120-1126.
-
(2007)
Diabetes
, vol.56
, pp. 1120-1126
-
-
Chan, O.1
Lawson, M.2
Zhu, W.3
Beverly, J.L.4
Sherwin, R.S.5
-
37
-
-
38549142801
-
Inhibition of agouti-related peptide expression by glucose in a clonal hypothalamic neuronal cell line is mediated by glycolysis, not oxidative phosphorylation
-
Cheng H., Isoda F., Belsham D.D., Mobbs C.V. Inhibition of agouti-related peptide expression by glucose in a clonal hypothalamic neuronal cell line is mediated by glycolysis, not oxidative phosphorylation. Endocrinology 2008, 149:703-710.
-
(2008)
Endocrinology
, vol.149
, pp. 703-710
-
-
Cheng, H.1
Isoda, F.2
Belsham, D.D.3
Mobbs, C.V.4
-
38
-
-
82355175978
-
Kidney aging - inevitable or preventable?
-
Choudhury D., Levi M. Kidney aging - inevitable or preventable?. Nat. Rev. Nephrol. 2011, 7:706-717.
-
(2011)
Nat. Rev. Nephrol.
, vol.7
, pp. 706-717
-
-
Choudhury, D.1
Levi, M.2
-
39
-
-
0028933936
-
Counterregulation of hypoglycemia. Skeletal muscle glycogen metabolism during three hours of physiological hyperinsulinemia in humans
-
Cohen N., Rossetti L., Shlimovich P., Halberstam M., Hu M., Shamoon H. Counterregulation of hypoglycemia. Skeletal muscle glycogen metabolism during three hours of physiological hyperinsulinemia in humans. Diabetes 1995, 44:423-430.
-
(1995)
Diabetes
, vol.44
, pp. 423-430
-
-
Cohen, N.1
Rossetti, L.2
Shlimovich, P.3
Halberstam, M.4
Hu, M.5
Shamoon, H.6
-
40
-
-
0016803107
-
Epigenetic influences on the lifespan of the Drosophila: existence of an optimal growth temperature for adult longevity
-
Cohet Y. Epigenetic influences on the lifespan of the Drosophila: existence of an optimal growth temperature for adult longevity. Exp. Gerontol. 1975, 10:181-184.
-
(1975)
Exp. Gerontol.
, vol.10
, pp. 181-184
-
-
Cohet, Y.1
-
41
-
-
33750681712
-
Transgenic mice with a reduced core body temperature have an increased life span
-
Conti B., Sanchez-Alavez M., Winsky-Sommerer R., Morale M.C., Lucero J., Brownell S., Fabre V., Huitron-Resendiz S., Henriksen S., Zorrilla E.P., de Lecea L., Bartfai T. Transgenic mice with a reduced core body temperature have an increased life span. Science 2006, 314:825-828.
-
(2006)
Science
, vol.314
, pp. 825-828
-
-
Conti, B.1
Sanchez-Alavez, M.2
Winsky-Sommerer, R.3
Morale, M.C.4
Lucero, J.5
Brownell, S.6
Fabre, V.7
Huitron-Resendiz, S.8
Henriksen, S.9
Zorrilla, E.P.10
de Lecea, L.11
Bartfai, T.12
-
42
-
-
33646582664
-
Hypothalamic mTOR signaling regulates food intake
-
Cota D., Proulx K., Smith K.A., Kozma S.C., Thomas G., Woods S.C., Seeley R.J. Hypothalamic mTOR signaling regulates food intake. Science 2006, 312:927-930.
-
(2006)
Science
, vol.312
, pp. 927-930
-
-
Cota, D.1
Proulx, K.2
Smith, K.A.3
Kozma, S.C.4
Thomas, G.5
Woods, S.C.6
Seeley, R.J.7
-
43
-
-
0030913976
-
Hierarchy of physiological responses to hypoglycemia: relevance to clinical hypoglycemia in type I (insulin dependent) diabetes mellitus
-
Cryer P.E. Hierarchy of physiological responses to hypoglycemia: relevance to clinical hypoglycemia in type I (insulin dependent) diabetes mellitus. Horm. Metab. Res. 1997, 29:92-96.
-
(1997)
Horm. Metab. Res.
, vol.29
, pp. 92-96
-
-
Cryer, P.E.1
-
44
-
-
67650659852
-
Anti-oxidative and anti-inflammatory vasoprotective effects of caloric restriction in aging: role of circulating factors and SIRT1
-
Csiszar A., Labinskyy N., Jimenez R., Pinto J.T., Ballabh P., Losonczy G., Pearson K.J., de Cabo R., Ungvari Z. Anti-oxidative and anti-inflammatory vasoprotective effects of caloric restriction in aging: role of circulating factors and SIRT1. Mech. Ageing Dev. 2009, 130:518-527.
-
(2009)
Mech. Ageing Dev.
, vol.130
, pp. 518-527
-
-
Csiszar, A.1
Labinskyy, N.2
Jimenez, R.3
Pinto, J.T.4
Ballabh, P.5
Losonczy, G.6
Pearson, K.J.7
de Cabo, R.8
Ungvari, Z.9
-
45
-
-
33750607418
-
Chronic jet-lag increases mortality in aged mice
-
Davidson A.J., Sellix M.T., Daniel J., Yamazaki S., Menaker M., Block G.D. Chronic jet-lag increases mortality in aged mice. Curr. Biol. 2006, 16:R914-R916.
-
(2006)
Curr. Biol.
, vol.16
-
-
Davidson, A.J.1
Sellix, M.T.2
Daniel, J.3
Yamazaki, S.4
Menaker, M.5
Block, G.D.6
-
46
-
-
0038241881
-
An in vitro model of caloric restriction
-
de Cabo R., Furer-Galban S., Anson R.M., Gilman C., Gorospe M., Lane M.A. An in vitro model of caloric restriction. Exp. Gerontol. 2003, 38:631-639.
-
(2003)
Exp. Gerontol.
, vol.38
, pp. 631-639
-
-
de Cabo, R.1
Furer-Galban, S.2
Anson, R.M.3
Gilman, C.4
Gorospe, M.5
Lane, M.A.6
-
47
-
-
31044451078
-
Complete rescue of obesity, diabetes, and infertility in db/db mice by neuron-specific LEPR-B transgenes
-
de Luca C., Kowalski T.J., Zhang Y., Elmquist J.K., Lee C., Kilimann M.W., Ludwig T., Liu S.M., Chua S.C. Complete rescue of obesity, diabetes, and infertility in db/db mice by neuron-specific LEPR-B transgenes. J. Clin. Invest. 2005, 115:3484-3493.
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 3484-3493
-
-
de Luca, C.1
Kowalski, T.J.2
Zhang, Y.3
Elmquist, J.K.4
Lee, C.5
Kilimann, M.W.6
Ludwig, T.7
Liu, S.M.8
Chua, S.C.9
-
48
-
-
0033527569
-
Peroxisome proliferator-activated receptor alpha negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-kappaB and AP-1
-
Delerive P., De Bosscher K., Besnard S., Vanden Berghe W., Peters J.M., Gonzalez F.J., Fruchart J.C., Tedgui A., Haegeman G., Staels B. Peroxisome proliferator-activated receptor alpha negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-kappaB and AP-1. J. Biol. Chem. 1999, 274:32048-32054.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 32048-32054
-
-
Delerive, P.1
De Bosscher, K.2
Besnard, S.3
Vanden Berghe, W.4
Peters, J.M.5
Gonzalez, F.J.6
Fruchart, J.C.7
Tedgui, A.8
Haegeman, G.9
Staels, B.10
-
49
-
-
0033566286
-
Dietary restriction and 2-deoxyglucose administration improve behavioral outcome and reduce degeneration of dopaminergic neurons in models of Parkinson's disease
-
Duan W., Mattson M.P. Dietary restriction and 2-deoxyglucose administration improve behavioral outcome and reduce degeneration of dopaminergic neurons in models of Parkinson's disease. J. Neurosci. Res. 1999, 57:195-206.
-
(1999)
J. Neurosci. Res.
, vol.57
, pp. 195-206
-
-
Duan, W.1
Mattson, M.P.2
-
50
-
-
0037418339
-
Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice
-
Duan W., Guo Z., Jiang H., Ware M., Li X.J., Mattson M.P. Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice. Proc. Natl. Acad. Sci. USA 2003, 100:2911-2916.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 2911-2916
-
-
Duan, W.1
Guo, Z.2
Jiang, H.3
Ware, M.4
Li, X.J.5
Mattson, M.P.6
-
51
-
-
79952274829
-
Deficiency of circadian protein CLOCK reduces lifespan and increases age-related cataract development in mice
-
Dubrovsky Y.V., Samsa W.E., Kondratov R.V. Deficiency of circadian protein CLOCK reduces lifespan and increases age-related cataract development in mice. Aging (Albany, NY) 2010, 2:936-944.
-
(2010)
Aging (Albany, NY)
, vol.2
, pp. 936-944
-
-
Dubrovsky, Y.V.1
Samsa, W.E.2
Kondratov, R.V.3
-
52
-
-
0036303140
-
Glucokinase is the likely mediator of glucosensing in both glucose-excited and glucose-inhibited central neurons
-
Dunn-Meynell A.A., Routh V.H., Kang L., Gaspers L., Levin B.E. Glucokinase is the likely mediator of glucosensing in both glucose-excited and glucose-inhibited central neurons. Diabetes 2002, 51:2056-2065.
-
(2002)
Diabetes
, vol.51
, pp. 2056-2065
-
-
Dunn-Meynell, A.A.1
Routh, V.H.2
Kang, L.3
Gaspers, L.4
Levin, B.E.5
-
53
-
-
0033082380
-
From lesions to leptin: hypothalamic control of food intake and body weight
-
Elmquist J.K., Elias C.F., Saper C.B. From lesions to leptin: hypothalamic control of food intake and body weight. Neuron 1999, 22:221-232.
-
(1999)
Neuron
, vol.22
, pp. 221-232
-
-
Elmquist, J.K.1
Elias, C.F.2
Saper, C.B.3
-
54
-
-
4644298411
-
+ channels play a key role in sensing hypoglycemia and triggering counter regulatory epinephrine and glucagon responses
-
+ channels play a key role in sensing hypoglycemia and triggering counter regulatory epinephrine and glucagon responses. Diabetes 2004, 53:2542-2551.
-
(2004)
Diabetes
, vol.53
, pp. 2542-2551
-
-
Evans, M.L.1
McCrimmon, R.J.2
Flanagan, D.E.3
Keshavarz, T.4
Fan, X.5
McNay, E.C.6
Jacob, R.J.7
Sherwin, R.S.8
-
55
-
-
29544436528
-
Homeostatic responses to caloric restriction: influence of background metabolic rate
-
Evans S.A., Parsons A.D., Overton J.M. Homeostatic responses to caloric restriction: influence of background metabolic rate. J. Appl. Physiol. 2005, 99:1336-1342.
-
(2005)
J. Appl. Physiol.
, vol.99
, pp. 1336-1342
-
-
Evans, S.A.1
Parsons, A.D.2
Overton, J.M.3
-
56
-
-
57349093783
-
Neuroendocrine factors in the regulation of inflammation: excessive adiposity and calorie restriction
-
Fontana L. Neuroendocrine factors in the regulation of inflammation: excessive adiposity and calorie restriction. Exp. Gerontol. 2009, 44:41-45.
-
(2009)
Exp. Gerontol.
, vol.44
, pp. 41-45
-
-
Fontana, L.1
-
57
-
-
34547223572
-
Calorie restriction or exercise: effects on coronary heart disease risk factors. A randomized, controlled trial
-
Fontana L., Villareal D.T., Weiss E.P., Racette S.B., Steger-May K., Klein S., Holloszy J.O. Calorie restriction or exercise: effects on coronary heart disease risk factors. A randomized, controlled trial. Am. J. Physiol. Endocrinol. Metab. 2007, 293:E197-E202.
-
(2007)
Am. J. Physiol. Endocrinol. Metab.
, vol.293
-
-
Fontana, L.1
Villareal, D.T.2
Weiss, E.P.3
Racette, S.B.4
Steger-May, K.5
Klein, S.6
Holloszy, J.O.7
-
58
-
-
77949424755
-
Effects of long-term calorie restriction and endurance exercise on glucose tolerance, insulin action, and adipokine production
-
Fontana L., Klein S., Holloszy J.O. Effects of long-term calorie restriction and endurance exercise on glucose tolerance, insulin action, and adipokine production. Age (Dordr) 2010, 32:97-108.
-
(2010)
Age (Dordr)
, vol.32
, pp. 97-108
-
-
Fontana, L.1
Klein, S.2
Holloszy, J.O.3
-
59
-
-
77951176737
-
Extending healthy life span - from yeast to humans
-
Fontana L., Partridge L., Longo V.D. Extending healthy life span - from yeast to humans. Science 2010, 328:321-326.
-
(2010)
Science
, vol.328
, pp. 321-326
-
-
Fontana, L.1
Partridge, L.2
Longo, V.D.3
-
60
-
-
0015525433
-
The hypothermia of hypoglycemia. Studies with 2-deoxy-d-glucose in normal human subjects and mice
-
Freinkel N., Metzger B.E., Harris E., Robinson S., Mager M. The hypothermia of hypoglycemia. Studies with 2-deoxy-d-glucose in normal human subjects and mice. N. Engl. J. Med. 1972, 287:841-845.
-
(1972)
N. Engl. J. Med.
, vol.287
, pp. 841-845
-
-
Freinkel, N.1
Metzger, B.E.2
Harris, E.3
Robinson, S.4
Mager, M.5
-
61
-
-
80051623066
-
Circadian rhythms, aging, and life span in mammals
-
Froy O. Circadian rhythms, aging, and life span in mammals. Physiology (Bethesda) 2011, 26:225-235.
-
(2011)
Physiology (Bethesda)
, vol.26
, pp. 225-235
-
-
Froy, O.1
-
62
-
-
77953454534
-
Effect of feeding regimens on circadian rhythms: implications for aging and longevity
-
Froy O., Miskin R. Effect of feeding regimens on circadian rhythms: implications for aging and longevity. Aging (Albany, NY) 2010, 2:7-27.
-
(2010)
Aging (Albany, NY)
, vol.2
, pp. 7-27
-
-
Froy, O.1
Miskin, R.2
-
63
-
-
44449155949
-
Differential rescue of light- and food-entrainable circadian rhythms
-
Fuller P.M., Lu J., Saper C.B. Differential rescue of light- and food-entrainable circadian rhythms. Science 2008, 320:1074-1077.
-
(2008)
Science
, vol.320
, pp. 1074-1077
-
-
Fuller, P.M.1
Lu, J.2
Saper, C.B.3
-
64
-
-
84855994224
-
A role for neuronal cAMP responsive-element binding (CREB)-1 in brain responses to calorie restriction
-
Fusco S., Ripoli C., Podda M.V., Ranieri S.C., Leone L., Toietta G., McBurney M.W., Schutz G., Riccio A., Grassi C., Galeotti T., Pani G. A role for neuronal cAMP responsive-element binding (CREB)-1 in brain responses to calorie restriction. Proc. Natl. Acad. Sci. USA 2012, 109:621-626.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 621-626
-
-
Fusco, S.1
Ripoli, C.2
Podda, M.V.3
Ranieri, S.C.4
Leone, L.5
Toietta, G.6
McBurney, M.W.7
Schutz, G.8
Riccio, A.9
Grassi, C.10
Galeotti, T.11
Pani, G.12
-
65
-
-
58249123839
-
Molecular recognition of long chain fatty acids by peroxisome proliferator-activated receptor A
-
Gani O.S. Molecular recognition of long chain fatty acids by peroxisome proliferator-activated receptor A. Med. Chem. Res. 2009, 18:8-19.
-
(2009)
Med. Chem. Res.
, vol.18
, pp. 8-19
-
-
Gani, O.S.1
-
66
-
-
33750443292
-
2-Deoxy-d-glucose reduces epilepsy progression by NRSF-CtBP-dependent metabolic regulation of chromatin structure
-
Garriga-Canut M., Schoenike B., Qazi R., Bergendahl K., Daley T.J., Pfender R.M., Morrison J.F., Ockuly J., Stafstrom C., Sutula T., Roopra A. 2-Deoxy-d-glucose reduces epilepsy progression by NRSF-CtBP-dependent metabolic regulation of chromatin structure. Nat. Neurosci. 2006, 9:1382-1387.
-
(2006)
Nat. Neurosci.
, vol.9
, pp. 1382-1387
-
-
Garriga-Canut, M.1
Schoenike, B.2
Qazi, R.3
Bergendahl, K.4
Daley, T.J.5
Pfender, R.M.6
Morrison, J.F.7
Ockuly, J.8
Stafstrom, C.9
Sutula, T.10
Roopra, A.11
-
67
-
-
63549108476
-
Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans
-
Greer E.L., Brunet A. Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans. Aging Cell 2009, 8:113-127.
-
(2009)
Aging Cell
, vol.8
, pp. 113-127
-
-
Greer, E.L.1
Brunet, A.2
-
68
-
-
34848850156
-
An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans
-
Greer E.L., Dowlatshahi D., Banko M.R., Villen J., Hoang K., Blanchard D., Gygi S.P., Brunet A. An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans. Curr. Biol. 2007, 17:1646-1656.
-
(2007)
Curr. Biol.
, vol.17
, pp. 1646-1656
-
-
Greer, E.L.1
Dowlatshahi, D.2
Banko, M.R.3
Villen, J.4
Hoang, K.5
Blanchard, D.6
Gygi, S.P.7
Brunet, A.8
-
69
-
-
0033009672
-
Relationship between blood glucose level and mortality in type 2 diabetes mellitus: a systematic review
-
Groeneveld Y., Petri H., Hermans J., Springer M.P. Relationship between blood glucose level and mortality in type 2 diabetes mellitus: a systematic review. Diabet. Med. 1999, 16:2-13.
-
(1999)
Diabet. Med.
, vol.16
, pp. 2-13
-
-
Groeneveld, Y.1
Petri, H.2
Hermans, J.3
Springer, M.P.4
-
70
-
-
77649195357
-
Molecular evolution and functional characterization of Drosophila insulin-like peptides
-
Gronke S., Clarke D.F., Broughton S., Andrews T.D., Partridge L. Molecular evolution and functional characterization of Drosophila insulin-like peptides. PLoS Genet. 2010, 6:e1000857.
-
(2010)
PLoS Genet.
, vol.6
-
-
Gronke, S.1
Clarke, D.F.2
Broughton, S.3
Andrews, T.D.4
Partridge, L.5
-
71
-
-
84855996047
-
Gene profiling reveals a role for stress hormones in the molecular and behavioral response to food restriction
-
Guarnieri D.J., Brayton C.E., Richards S.M., Maldonado-Aviles J., Trinko J.R., Nelson J., Taylor J.R., Gourley S.L., DiLeone R.J. Gene profiling reveals a role for stress hormones in the molecular and behavioral response to food restriction. Biol. Psychiatry 2012, 71:358-365.
-
(2012)
Biol. Psychiatry
, vol.71
, pp. 358-365
-
-
Guarnieri, D.J.1
Brayton, C.E.2
Richards, S.M.3
Maldonado-Aviles, J.4
Trinko, J.R.5
Nelson, J.6
Taylor, J.R.7
Gourley, S.L.8
DiLeone, R.J.9
-
72
-
-
12244299825
-
Caloric restriction increases gluconeogenic and transaminase enzyme activities in mouse liver
-
Hagopian K., Ramsey J.J., Weindruch R. Caloric restriction increases gluconeogenic and transaminase enzyme activities in mouse liver. Exp. Gerontol. 2003, 38:267-278.
-
(2003)
Exp. Gerontol.
, vol.38
, pp. 267-278
-
-
Hagopian, K.1
Ramsey, J.J.2
Weindruch, R.3
-
73
-
-
12244302878
-
Influence of age and caloric restriction on liver glycolytic enzyme activities and metabolite concentrations in mice
-
Hagopian K., Ramsey J.J., Weindruch R. Influence of age and caloric restriction on liver glycolytic enzyme activities and metabolite concentrations in mice. Exp. Gerontol. 2003, 38:253-266.
-
(2003)
Exp. Gerontol.
, vol.38
, pp. 253-266
-
-
Hagopian, K.1
Ramsey, J.J.2
Weindruch, R.3
-
75
-
-
0029097240
-
Hyperadrenocorticism and food restriction-induced life extension in the rat: evidence for divergent regulation of pituitary proopiomelanocortin RNA and adrenocorticotropic hormone biosynthesis
-
Han E.S., Levin N., Bengani N., Roberts J.L., Suh Y., Karelus K., Nelson J.F. Hyperadrenocorticism and food restriction-induced life extension in the rat: evidence for divergent regulation of pituitary proopiomelanocortin RNA and adrenocorticotropic hormone biosynthesis. J. Gerontol. A: Biol. Sci. Med. Sci. 1995, 50:B288-B294.
-
(1995)
J. Gerontol. A: Biol. Sci. Med. Sci.
, vol.50
-
-
Han, E.S.1
Levin, N.2
Bengani, N.3
Roberts, J.L.4
Suh, Y.5
Karelus, K.6
Nelson, J.F.7
-
76
-
-
33846423520
-
Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans
-
Hansen M., Taubert S., Crawford D., Libina N., Lee S.J., Kenyon C. Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans. Aging Cell 2007, 6:95-110.
-
(2007)
Aging Cell
, vol.6
, pp. 95-110
-
-
Hansen, M.1
Taubert, S.2
Crawford, D.3
Libina, N.4
Lee, S.J.5
Kenyon, C.6
-
77
-
-
0032830174
-
Role of the sympathetic nervous system and insulin in enhancing glucose uptake in peripheral tissues after intrahypothalamic injection of leptin in rats
-
Haque M.S., Minokoshi Y., Hamai M., Iwai M., Horiuchi M., Shimazu T. Role of the sympathetic nervous system and insulin in enhancing glucose uptake in peripheral tissues after intrahypothalamic injection of leptin in rats. Diabetes 1999, 48:1706-1712.
-
(1999)
Diabetes
, vol.48
, pp. 1706-1712
-
-
Haque, M.S.1
Minokoshi, Y.2
Hamai, M.3
Iwai, M.4
Horiuchi, M.5
Shimazu, T.6
-
78
-
-
67650944993
-
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
-
Harrison D.E., Strong R., Sharp Z.D., Nelson J.F., Astle C.M., Flurkey K., Nadon N.L., Wilkinson J.E., Frenkel K., Carter C.S., Pahor M., Javors M.A., Fernandez E., Miller R.A. Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature 2009, 460:392-395.
-
(2009)
Nature
, vol.460
, pp. 392-395
-
-
Harrison, D.E.1
Strong, R.2
Sharp, Z.D.3
Nelson, J.F.4
Astle, C.M.5
Flurkey, K.6
Nadon, N.L.7
Wilkinson, J.E.8
Frenkel, K.9
Carter, C.S.10
Pahor, M.11
Javors, M.A.12
Fernandez, E.13
Miller, R.A.14
-
79
-
-
0030875338
-
Dietary restrictions and cancer
-
Hart R.W., Turturro A. Dietary restrictions and cancer. Environ Health Perspect. 1997, 105(Suppl. 4):989-992.
-
(1997)
Environ Health Perspect.
, vol.105
, Issue.SUPPL. 4
, pp. 989-992
-
-
Hart, R.W.1
Turturro, A.2
-
80
-
-
0026035949
-
Reduced neuroendocrine and symptomatic responses to subsequent hypoglycemia after 1 episode of hypoglycemia in nondiabetic humans
-
Heller S.R., Cryer P.E. Reduced neuroendocrine and symptomatic responses to subsequent hypoglycemia after 1 episode of hypoglycemia in nondiabetic humans. Diabetes 1991, 40:223-226.
-
(1991)
Diabetes
, vol.40
, pp. 223-226
-
-
Heller, S.R.1
Cryer, P.E.2
-
81
-
-
0034918201
-
Chronic food-restriction alters the expression of somatostatin and growth hormone-releasing hormone in the ovariectomised ewe
-
Henry B.A., Rao A., Tilbrook A.J., Clarke I.J. Chronic food-restriction alters the expression of somatostatin and growth hormone-releasing hormone in the ovariectomised ewe. J. Endocrinol. 2001, 170:R1-R5.
-
(2001)
J. Endocrinol.
, vol.170
-
-
Henry, B.A.1
Rao, A.2
Tilbrook, A.J.3
Clarke, I.J.4
-
82
-
-
0035855905
-
CREB regulates hepatic gluconeogenesis through the coactivator PGC-1
-
Herzig S., Long F., Jhala U.S., Hedrick S., Quinn R., Bauer A., Rudolph D., Schutz G., Yoon C., Puigserver P., Spiegelman B., Montminy M. CREB regulates hepatic gluconeogenesis through the coactivator PGC-1. Nature 2001, 413:179-183.
-
(2001)
Nature
, vol.413
, pp. 179-183
-
-
Herzig, S.1
Long, F.2
Jhala, U.S.3
Hedrick, S.4
Quinn, R.5
Bauer, A.6
Rudolph, D.7
Schutz, G.8
Yoon, C.9
Puigserver, P.10
Spiegelman, B.11
Montminy, M.12
-
83
-
-
21344469043
-
Dietary restriction affects striatal glutamate in the MPTP-induced mouse model of nigrostriatal degeneration
-
Holmer H.K., Keyghobadi M., Moore C., Menashe R.A., Meshul C.K. Dietary restriction affects striatal glutamate in the MPTP-induced mouse model of nigrostriatal degeneration. Synapse 2005, 57:100-112.
-
(2005)
Synapse
, vol.57
, pp. 100-112
-
-
Holmer, H.K.1
Keyghobadi, M.2
Moore, C.3
Menashe, R.A.4
Meshul, C.K.5
-
84
-
-
0019949378
-
Life span of the wild and mutant nematode Caenorhabditis elegans. Effects of sex, sterilization, and temperature
-
Hosono R., Mitsui Y., Sato Y., Aizawa S., Miwa J. Life span of the wild and mutant nematode Caenorhabditis elegans. Effects of sex, sterilization, and temperature. Exp. Gerontol. 1982, 17:163-172.
-
(1982)
Exp. Gerontol.
, vol.17
, pp. 163-172
-
-
Hosono, R.1
Mitsui, Y.2
Sato, Y.3
Aizawa, S.4
Miwa, J.5
-
85
-
-
31444448354
-
Antagonistic sensory cues generate gustatory plasticity in Caenorhabditis elegans
-
Hukema R.K., Rademakers S., Dekkers M.P., Burghoorn J., Jansen G. Antagonistic sensory cues generate gustatory plasticity in Caenorhabditis elegans. EMBO J. 2006, 25:312-322.
-
(2006)
EMBO J.
, vol.25
, pp. 312-322
-
-
Hukema, R.K.1
Rademakers, S.2
Dekkers, M.P.3
Burghoorn, J.4
Jansen, G.5
-
86
-
-
0032864653
-
Low body temperature in long-lived Ames dwarf mice at rest and during stress
-
Hunter W.S., Croson W.B., Bartke A., Gentry M.V., Meliska C.J. Low body temperature in long-lived Ames dwarf mice at rest and during stress. Physiol. Behav. 1999, 67:433-437.
-
(1999)
Physiol. Behav.
, vol.67
, pp. 433-437
-
-
Hunter, W.S.1
Croson, W.B.2
Bartke, A.3
Gentry, M.V.4
Meliska, C.J.5
-
87
-
-
0032185940
-
The significance of circadian organization for longevity in the golden hamster
-
Hurd M.W., Ralph M.R. The significance of circadian organization for longevity in the golden hamster. J. Biol. Rhythms 1998, 13:430-436.
-
(1998)
J. Biol. Rhythms
, vol.13
, pp. 430-436
-
-
Hurd, M.W.1
Ralph, M.R.2
-
88
-
-
78751704506
-
Glycolytic inhibition as a strategy for developing calorie restriction mimetics
-
Ingram D.K., Roth G.S. Glycolytic inhibition as a strategy for developing calorie restriction mimetics. Exp. Gerontol. 2011, 46:148-154.
-
(2011)
Exp. Gerontol.
, vol.46
, pp. 148-154
-
-
Ingram, D.K.1
Roth, G.S.2
-
89
-
-
4544311861
-
The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span
-
Jia K., Chen D., Riddle D.L. The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span. Development 2004, 131:3897-3906.
-
(2004)
Development
, vol.131
, pp. 3897-3906
-
-
Jia, K.1
Chen, D.2
Riddle, D.L.3
-
90
-
-
29244489494
-
Increased life span due to calorie restriction in respiratory-deficient yeast
-
Kaeberlein M., Hu D., Kerr E.O., Tsuchiya M., Westman E.A., Dang N., Fields S., Kennedy B.K. Increased life span due to calorie restriction in respiratory-deficient yeast. PLoS Genet. 2005, 1:e69.
-
(2005)
PLoS Genet.
, vol.1
-
-
Kaeberlein, M.1
Hu, D.2
Kerr, E.O.3
Tsuchiya, M.4
Westman, E.A.5
Dang, N.6
Fields, S.7
Kennedy, B.K.8
-
91
-
-
3042648746
-
Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway
-
Kapahi P., Zid B.M., Harper T., Koslover D., Sapin V., Benzer S. Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway. Curr. Biol. 2004, 14:885-890.
-
(2004)
Curr. Biol.
, vol.14
, pp. 885-890
-
-
Kapahi, P.1
Zid, B.M.2
Harper, T.3
Koslover, D.4
Sapin, V.5
Benzer, S.6
-
92
-
-
77955747346
-
With TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in aging
-
Kapahi P., Chen D., Rogers A.N., Katewa S.D., Li P.W., Thomas E.L., Kockel L. With TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in aging. Cell Metab. 2010, 11:453-465.
-
(2010)
Cell Metab.
, vol.11
, pp. 453-465
-
-
Kapahi, P.1
Chen, D.2
Rogers, A.N.3
Katewa, S.D.4
Li, P.W.5
Thomas, E.L.6
Kockel, L.7
-
93
-
-
79952148685
-
Disruption of circadian clocks has ramifications for metabolism, brain, and behavior
-
Karatsoreos I.N., Bhagat S., Bloss E.B., Morrison J.H., McEwen B.S. Disruption of circadian clocks has ramifications for metabolism, brain, and behavior. Proc. Natl. Acad. Sci. USA 2011, 108:1657-1662.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 1657-1662
-
-
Karatsoreos, I.N.1
Bhagat, S.2
Bloss, E.B.3
Morrison, J.H.4
McEwen, B.S.5
-
94
-
-
20444468137
-
CtBP represses p300-mediated transcriptional activation by direct association with its bromodomain
-
Kim J.H., Cho E.J., Kim S.T., Youn H.D. CtBP represses p300-mediated transcriptional activation by direct association with its bromodomain. Nat. Struct. Mol. Biol. 2005, 12:423-428.
-
(2005)
Nat. Struct. Mol. Biol.
, vol.12
, pp. 423-428
-
-
Kim, J.H.1
Cho, E.J.2
Kim, S.T.3
Youn, H.D.4
-
95
-
-
84863549071
-
FOXO1 in the ventromedial hypothalamus regulates energy balance
-
Kim K.W., Donato J., Berglund E.D., Choi Y.H., Kohno D., Elias C.F., Depinho R.A., Elmquist J.K. FOXO1 in the ventromedial hypothalamus regulates energy balance. J. Clin. Invest. 2012, 122:2578-2589.
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 2578-2589
-
-
Kim, K.W.1
Donato, J.2
Berglund, E.D.3
Choi, Y.H.4
Kohno, D.5
Elias, C.F.6
Depinho, R.A.7
Elmquist, J.K.8
-
96
-
-
33646590947
-
Forkhead protein FoxO1 mediates Agrp-dependent effects of leptin on food intake
-
Kitamura T., Feng Y., Kitamura Y.I., Chua S.C., Xu A.W., Barsh G.S., Rossetti L., Accili D. Forkhead protein FoxO1 mediates Agrp-dependent effects of leptin on food intake. Nat. Med. 2006, 12:534-540.
-
(2006)
Nat. Med.
, vol.12
, pp. 534-540
-
-
Kitamura, T.1
Feng, Y.2
Kitamura, Y.I.3
Chua, S.C.4
Xu, A.W.5
Barsh, G.S.6
Rossetti, L.7
Accili, D.8
-
97
-
-
0029081153
-
Hyperadrenocorticism, attenuated inflammation, and the life-prolonging action of food restriction in mice
-
Klebanov S., Diais S., Stavinoha W.B., Suh Y., Nelson J.F. Hyperadrenocorticism, attenuated inflammation, and the life-prolonging action of food restriction in mice. J. Gerontol. A: Biol. Sci. Med. Sci. 1995, 50:B79-B82.
-
(1995)
J. Gerontol. A: Biol. Sci. Med. Sci.
, vol.50
-
-
Klebanov, S.1
Diais, S.2
Stavinoha, W.B.3
Suh, Y.4
Nelson, J.F.5
-
98
-
-
33747586544
-
Peroxisome proliferator-activated receptor-alpha-null mice have increased white adipose tissue glucose utilization, GLUT4, and fat mass: role in liver and brain
-
Knauf C., Rieusset J., Foretz M., Cani P.D., Uldry M., Hosokawa M., Martinez E., Bringart M., Waget A., Kersten S., Desvergne B., Gremlich S., Wahli W., Seydoux J., Delzenne N.M., Thorens B., Burcelin R. Peroxisome proliferator-activated receptor-alpha-null mice have increased white adipose tissue glucose utilization, GLUT4, and fat mass: role in liver and brain. Endocrinology 2006, 147:4067-4078.
-
(2006)
Endocrinology
, vol.147
, pp. 4067-4078
-
-
Knauf, C.1
Rieusset, J.2
Foretz, M.3
Cani, P.D.4
Uldry, M.5
Hosokawa, M.6
Martinez, E.7
Bringart, M.8
Waget, A.9
Kersten, S.10
Desvergne, B.11
Gremlich, S.12
Wahli, W.13
Seydoux, J.14
Delzenne, N.M.15
Thorens, B.16
Burcelin, R.17
-
99
-
-
80755168947
-
Mediobasal hypothalamic SIRT1 is essential for resveratrol's effects on insulin action in rats
-
Knight C.M., Gutierrez-Juarez R., Lam T.K., Arrieta-Cruz I., Huang L., Schwartz G., Barzilai N., Rossetti L. Mediobasal hypothalamic SIRT1 is essential for resveratrol's effects on insulin action in rats. Diabetes 2011, 60:2691-2700.
-
(2011)
Diabetes
, vol.60
, pp. 2691-2700
-
-
Knight, C.M.1
Gutierrez-Juarez, R.2
Lam, T.K.3
Arrieta-Cruz, I.4
Huang, L.5
Schwartz, G.6
Barzilai, N.7
Rossetti, L.8
-
100
-
-
0030606113
-
A tumor preventive effect of dietary restriction is antagonized by a high housing temperature through deprivation of torpor
-
Koizumi A., Wada Y., Tuskada M., Kayo T., Naruse M., Horiuchi K., Mogi T., Yoshioka M., Sasaki M., Miyamaura Y., Abe T., Ohtomo K., Walford R.L. A tumor preventive effect of dietary restriction is antagonized by a high housing temperature through deprivation of torpor. Mech. Ageing Dev. 1996, 92:67-82.
-
(1996)
Mech. Ageing Dev.
, vol.92
, pp. 67-82
-
-
Koizumi, A.1
Wada, Y.2
Tuskada, M.3
Kayo, T.4
Naruse, M.5
Horiuchi, K.6
Mogi, T.7
Yoshioka, M.8
Sasaki, M.9
Miyamaura, Y.10
Abe, T.11
Ohtomo, K.12
Walford, R.L.13
-
101
-
-
33746191906
-
Early aging and age-related pathologies in mice deficient in BMAL1, the core component of the circadian clock
-
Kondratov R.V., Kondratova A.A., Gorbacheva V.Y., Vykhovanets O.V., Antoch M.P. Early aging and age-related pathologies in mice deficient in BMAL1, the core component of the circadian clock. Genes Dev. 2006, 20:1868-1873.
-
(2006)
Genes Dev.
, vol.20
, pp. 1868-1873
-
-
Kondratov, R.V.1
Kondratova, A.A.2
Gorbacheva, V.Y.3
Vykhovanets, O.V.4
Antoch, M.P.5
-
102
-
-
0028060029
-
Nuclear protein CBP is a coactivator for the transcription factor CREB
-
Kwok R.P., Lundblad J.R., Chrivia J.C., Richards J.P., Bachinger H.P., Brennan R.G., Roberts S.G., Green M.R., Goodman R.H. Nuclear protein CBP is a coactivator for the transcription factor CREB. Nature 1994, 370:223-226.
-
(1994)
Nature
, vol.370
, pp. 223-226
-
-
Kwok, R.P.1
Lundblad, J.R.2
Chrivia, J.C.3
Richards, J.P.4
Bachinger, H.P.5
Brennan, R.G.6
Roberts, S.G.7
Green, M.R.8
Goodman, R.H.9
-
103
-
-
23244458439
-
Regulation of blood glucose by hypothalamic pyruvate metabolism
-
Lam T.K., Gutierrez-Juarez R., Pocai A., Rossetti L. Regulation of blood glucose by hypothalamic pyruvate metabolism. Science 2005, 309:943-947.
-
(2005)
Science
, vol.309
, pp. 943-947
-
-
Lam, T.K.1
Gutierrez-Juarez, R.2
Pocai, A.3
Rossetti, L.4
-
104
-
-
0029994960
-
Calorie restriction lowers body temperature in rhesus monkeys, consistent with a postulated anti-aging mechanism in rodents
-
Lane M.A., Baer D.J., Rumpler W.V., Weindruch R., Ingram D.K., Tilmont E.M., Cutler R.G., Roth G.S. Calorie restriction lowers body temperature in rhesus monkeys, consistent with a postulated anti-aging mechanism in rodents. Proc. Natl. Acad. Sci. USA 1996, 93:4159-4164.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 4159-4164
-
-
Lane, M.A.1
Baer, D.J.2
Rumpler, W.V.3
Weindruch, R.4
Ingram, D.K.5
Tilmont, E.M.6
Cutler, R.G.7
Roth, G.S.8
-
105
-
-
33847421281
-
Multiple sensory G proteins in the olfactory, gustatory and nociceptive neurons modulate longevity in Caenorhabditis elegans
-
Lans H., Jansen G. Multiple sensory G proteins in the olfactory, gustatory and nociceptive neurons modulate longevity in Caenorhabditis elegans. Dev. Biol. 2007, 303:474-482.
-
(2007)
Dev. Biol.
, vol.303
, pp. 474-482
-
-
Lans, H.1
Jansen, G.2
-
106
-
-
0037069375
-
Transcriptional profiles associated with aging and middle age-onset caloric restriction in mouse hearts
-
Lee C.K., Allison D.B., Brand J., Weindruch R., Prolla T.A. Transcriptional profiles associated with aging and middle age-onset caloric restriction in mouse hearts. Proc. Natl. Acad. Sci. USA 2002, 99:14988-14993.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 14988-14993
-
-
Lee, C.K.1
Allison, D.B.2
Brand, J.3
Weindruch, R.4
Prolla, T.A.5
-
107
-
-
70350365110
-
Glucose shortens the life span of C. elegans by downregulating DAF-16/FOXO activity and aquaporin gene expression
-
Lee S.J., Murphy C.T., Kenyon C. Glucose shortens the life span of C. elegans by downregulating DAF-16/FOXO activity and aquaporin gene expression. Cell Metab. 2009, 10:379-391.
-
(2009)
Cell Metab.
, vol.10
, pp. 379-391
-
-
Lee, S.J.1
Murphy, C.T.2
Kenyon, C.3
-
108
-
-
76249097841
-
Genetic variation in the murine lifespan response to dietary restriction: from life extension to life shortening
-
Liao C.Y., Rikke B.A., Johnson T.E., Diaz V., Nelson J.F. Genetic variation in the murine lifespan response to dietary restriction: from life extension to life shortening. Aging Cell 2010, 9:92-95.
-
(2010)
Aging Cell
, vol.9
, pp. 92-95
-
-
Liao, C.Y.1
Rikke, B.A.2
Johnson, T.E.3
Diaz, V.4
Nelson, J.F.5
-
109
-
-
33847259770
-
Regulation of Drosophila life span by olfaction and food-derived odors
-
Libert S., Zwiener J., Chu X., Vanvoorhies W., Roman G., Pletcher S.D. Regulation of Drosophila life span by olfaction and food-derived odors. Science 2007, 315:1133-1137.
-
(2007)
Science
, vol.315
, pp. 1133-1137
-
-
Libert, S.1
Zwiener, J.2
Chu, X.3
Vanvoorhies, W.4
Roman, G.5
Pletcher, S.D.6
-
110
-
-
0034703217
-
Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae
-
Lin S.J., Defossez P.A., Guarente L. Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae. Science 2000, 289:2126-2128.
-
(2000)
Science
, vol.289
, pp. 2126-2128
-
-
Lin, S.J.1
Defossez, P.A.2
Guarente, L.3
-
111
-
-
0037130175
-
Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration
-
Lin S.J., Kaeberlein M., Andalis A.A., Sturtz L.A., Defossez P.A., Culotta V.C., Fink G.R., Guarente L. Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration. Nature 2002, 418:344-348.
-
(2002)
Nature
, vol.418
, pp. 344-348
-
-
Lin, S.J.1
Kaeberlein, M.2
Andalis, A.A.3
Sturtz, L.A.4
Defossez, P.A.5
Culotta, V.C.6
Fink, G.R.7
Guarente, L.8
-
112
-
-
0000562418
-
Increased growth and life-span with lowered ambient temperature in the annual fish, Cynolebia adloffi
-
Liu R.K., Walford R.L. Increased growth and life-span with lowered ambient temperature in the annual fish, Cynolebia adloffi. Nature 1966, 212:1277-1278.
-
(1966)
Nature
, vol.212
, pp. 1277-1278
-
-
Liu, R.K.1
Walford, R.L.2
-
113
-
-
0015471792
-
The effect of lowered body temperature on lifespan and immune and non-immune processes
-
Liu R.K., Walford R.L. The effect of lowered body temperature on lifespan and immune and non-immune processes. Gerontologia 1972, 18:363-388.
-
(1972)
Gerontologia
, vol.18
, pp. 363-388
-
-
Liu, R.K.1
Walford, R.L.2
-
114
-
-
0016733668
-
Mid-life temperature-transfer effects on life-span of annual fish
-
Liu R.K., Walford R.L. Mid-life temperature-transfer effects on life-span of annual fish. J. Gerontol. 1975, 30:129-131.
-
(1975)
J. Gerontol.
, vol.30
, pp. 129-131
-
-
Liu, R.K.1
Walford, R.L.2
-
115
-
-
0016759087
-
Effect of temperature-transfer on growth of laboratory populations of a South American annual fish Cynolebias bellottii
-
Liu R.K., Leung B.E., Walford R.L. Effect of temperature-transfer on growth of laboratory populations of a South American annual fish Cynolebias bellottii. Growth 1975, 39:337-343.
-
(1975)
Growth
, vol.39
, pp. 337-343
-
-
Liu, R.K.1
Leung, B.E.2
Walford, R.L.3
-
116
-
-
0000092997
-
Is there a temperature coefficient for the duration of life?
-
Loeb J., Northrop J.H. Is there a temperature coefficient for the duration of life?. Proc. Natl. Acad. Sci. USA 1916, 2:456-457.
-
(1916)
Proc. Natl. Acad. Sci. USA
, vol.2
, pp. 456-457
-
-
Loeb, J.1
Northrop, J.H.2
-
117
-
-
77956721803
-
Mechanisms of the sympathoadrenal response to hypoglycemia
-
Maggs D.G., Sherwin R.S. Mechanisms of the sympathoadrenal response to hypoglycemia. Adv. Pharmacol. 1998, 42:622-626.
-
(1998)
Adv. Pharmacol.
, vol.42
, pp. 622-626
-
-
Maggs, D.G.1
Sherwin, R.S.2
-
118
-
-
33746336247
-
Caloric restriction in C57BL/6J mice mimics therapeutic fasting in humans
-
Mahoney L.B., Denny C.A., Seyfried T.N. Caloric restriction in C57BL/6J mice mimics therapeutic fasting in humans. Lipids Health Dis. 2006, 5:13.
-
(2006)
Lipids Health Dis.
, vol.5
, pp. 13
-
-
Mahoney, L.B.1
Denny, C.A.2
Seyfried, T.N.3
-
119
-
-
84858342119
-
Lifelong rapamycin administration ameliorates age-dependent cognitive deficits by reducing IL-1beta and enhancing NMDA signaling
-
Majumder S., Caccamo A., Medina D.X., Benavides A.D., Javors M.A., Kraig E., Strong R., Richardson A., Oddo S. Lifelong rapamycin administration ameliorates age-dependent cognitive deficits by reducing IL-1beta and enhancing NMDA signaling. Aging Cell 2012, 11:326-335.
-
(2012)
Aging Cell
, vol.11
, pp. 326-335
-
-
Majumder, S.1
Caccamo, A.2
Medina, D.X.3
Benavides, A.D.4
Javors, M.A.5
Kraig, E.6
Strong, R.7
Richardson, A.8
Oddo, S.9
-
120
-
-
80053106868
-
Calorie restriction and stroke
-
Manzanero S., Gelderblom M., Magnus T., Arumugam T.V. Calorie restriction and stroke. Exp. Transl. Stroke Med. 2011, 3:8.
-
(2011)
Exp. Transl. Stroke Med.
, vol.3
, pp. 8
-
-
Manzanero, S.1
Gelderblom, M.2
Magnus, T.3
Arumugam, T.V.4
-
121
-
-
34250838974
-
The role of hormesis in life extension by dietary restriction
-
Masoro E.J. The role of hormesis in life extension by dietary restriction. Interdiscip. Top Gerontol. 2007, 35:1-17.
-
(2007)
Interdiscip. Top Gerontol.
, vol.35
, pp. 1-17
-
-
Masoro, E.J.1
-
123
-
-
19944427435
-
Caloric restriction increases neurotrophic factor levels and attenuates neurochemical and behavioral deficits in a primate model of Parkinson's disease
-
Maswood N., Young J., Tilmont E., Zhang Z., Gash D.M., Gerhardt G.A., Grondin R., Roth G.S., Mattison J., Lane M.A., Carson R.E., Cohen R.M., Mouton P.R., Quigley C., Mattson M.P., Ingram D.K. Caloric restriction increases neurotrophic factor levels and attenuates neurochemical and behavioral deficits in a primate model of Parkinson's disease. Proc. Natl. Acad. Sci. USA 2004, 101:18171-18176.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 18171-18176
-
-
Maswood, N.1
Young, J.2
Tilmont, E.3
Zhang, Z.4
Gash, D.M.5
Gerhardt, G.A.6
Grondin, R.7
Roth, G.S.8
Mattison, J.9
Lane, M.A.10
Carson, R.E.11
Cohen, R.M.12
Mouton, P.R.13
Quigley, C.14
Mattson, M.P.15
Ingram, D.K.16
-
124
-
-
0030067124
-
A lesson in metabolic regulation inspired by the glucokinase glucose sensor paradigm
-
Matschinsky F.M., Lecture Banting A lesson in metabolic regulation inspired by the glucokinase glucose sensor paradigm. Diabetes 1995, 45(1996):223-241.
-
(1995)
Diabetes
, vol.45
, Issue.1996
, pp. 223-241
-
-
Matschinsky, F.M.1
Lecture, B.2
-
125
-
-
84866163081
-
Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study
-
Mattison J.A., Roth G.S., Beasley T.M., Tilmont E.M., Handy A.M., Herbert R.L., Longo D.L., Allison D.B., Young J.E., Bryant M., Barnard D., Ward W.F., Qi W., Ingram D.K., de Cabo R. Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study. Nature 2012, 489:318-321.
-
(2012)
Nature
, vol.489
, pp. 318-321
-
-
Mattison, J.A.1
Roth, G.S.2
Beasley, T.M.3
Tilmont, E.M.4
Handy, A.M.5
Herbert, R.L.6
Longo, D.L.7
Allison, D.B.8
Young, J.E.9
Bryant, M.10
Barnard, D.11
Ward, W.F.12
Qi, W.13
Ingram, D.K.14
de Cabo, R.15
-
126
-
-
0022048716
-
Does food restriction retard aging by reducing the metabolic rate?
-
McCarter R., Masoro E.J., Yu B.P. Does food restriction retard aging by reducing the metabolic rate?. Am. J. Physiol. 1985, 248:E488-E490.
-
(1985)
Am. J. Physiol.
, vol.248
-
-
McCarter, R.1
Masoro, E.J.2
Yu, B.P.3
-
127
-
-
35349008023
-
Plasma glucose and the action of calorie restriction on aging
-
McCarter R., Mejia W., Ikeno Y., Monnier V., Kewitt K., Gibbs M., McMahan A., Strong R. Plasma glucose and the action of calorie restriction on aging. J. Gerontol. A: Biol. Sci. Med. Sci. 2007, 62:1059-1070.
-
(2007)
J. Gerontol. A: Biol. Sci. Med. Sci.
, vol.62
, pp. 1059-1070
-
-
McCarter, R.1
Mejia, W.2
Ikeno, Y.3
Monnier, V.4
Kewitt, K.5
Gibbs, M.6
McMahan, A.7
Strong, R.8
-
128
-
-
38549157632
-
Daily meal timing is not necessary for resetting the main circadian clock by calorie restriction
-
Mendoza J., Drevet K., Pevet P., Challet E. Daily meal timing is not necessary for resetting the main circadian clock by calorie restriction. J. Neuroendocrinol. 2008, 20:251-260.
-
(2008)
J. Neuroendocrinol.
, vol.20
, pp. 251-260
-
-
Mendoza, J.1
Drevet, K.2
Pevet, P.3
Challet, E.4
-
129
-
-
79951794971
-
Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice
-
Miller R.A., Harrison D.E., Astle C.M., Baur J.A., Boyd A.R., de Cabo R., Fernandez E., Flurkey K., Javors M.A., Nelson J.F., Orihuela C.J., Pletcher S., Sharp Z.D., Sinclair D., Starnes J.W., Wilkinson J.E., Nadon N.L., Strong R. Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice. J. Gerontol. A: Biol. Sci. Med. Sci. 2011, 66:191-201.
-
(2011)
J. Gerontol. A: Biol. Sci. Med. Sci.
, vol.66
, pp. 191-201
-
-
Miller, R.A.1
Harrison, D.E.2
Astle, C.M.3
Baur, J.A.4
Boyd, A.R.5
de Cabo, R.6
Fernandez, E.7
Flurkey, K.8
Javors, M.A.9
Nelson, J.F.10
Orihuela, C.J.11
Pletcher, S.12
Sharp, Z.D.13
Sinclair, D.14
Starnes, J.W.15
Wilkinson, J.E.16
Nadon, N.L.17
Strong, R.18
-
130
-
-
0028200927
-
Regulatory mechanism of the ventromedial hypothalamus in enhancing glucose uptake in skeletal muscles
-
Minokoshi Y., Okano Y., Shimazu T. Regulatory mechanism of the ventromedial hypothalamus in enhancing glucose uptake in skeletal muscles. Brain Res. 1994, 649:343-347.
-
(1994)
Brain Res.
, vol.649
, pp. 343-347
-
-
Minokoshi, Y.1
Okano, Y.2
Shimazu, T.3
-
131
-
-
0032971214
-
Microinjection of leptin into the ventromedial hypothalamus increases glucose uptake in peripheral tissues in rats
-
Minokoshi Y., Haque M.S., Shimazu T. Microinjection of leptin into the ventromedial hypothalamus increases glucose uptake in peripheral tissues in rats. Diabetes 1999, 48:287-291.
-
(1999)
Diabetes
, vol.48
, pp. 287-291
-
-
Minokoshi, Y.1
Haque, M.S.2
Shimazu, T.3
-
132
-
-
1842484296
-
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus
-
Minokoshi Y., Alquier T., Furukawa N., Kim Y.B., Lee A., Xue B., Mu J., Foufelle F., Ferre P., Birnbaum M.J., Stuck B.J., Kahn B.B. AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus. Nature 2004, 428:569-574.
-
(2004)
Nature
, vol.428
, pp. 569-574
-
-
Minokoshi, Y.1
Alquier, T.2
Furukawa, N.3
Kim, Y.B.4
Lee, A.5
Xue, B.6
Mu, J.7
Foufelle, F.8
Ferre, P.9
Birnbaum, M.J.10
Stuck, B.J.11
Kahn, B.B.12
-
133
-
-
79955967115
-
The arcuate nucleus and neuropeptide Y contribute to the antitumorigenic effect of calorie restriction
-
Minor R.K., Lopez M., Younts C.M., Jones B., Pearson K.J., Anson R.M., Dieguez C., de Cabo R. The arcuate nucleus and neuropeptide Y contribute to the antitumorigenic effect of calorie restriction. Aging Cell 2011, 10:483-492.
-
(2011)
Aging Cell
, vol.10
, pp. 483-492
-
-
Minor, R.K.1
Lopez, M.2
Younts, C.M.3
Jones, B.4
Pearson, K.J.5
Anson, R.M.6
Dieguez, C.7
de Cabo, R.8
-
134
-
-
0031888157
-
Rapid communication: hypothalamic pro-opiomelanocortin mRNA is reduced by fasting and in ob/ob and db/db mice, but is stimulated by leptin
-
Mizuno T.M., Kleopoulos S.P., Bergen H.T., Roberts J.L., Priest C.A., Mobbs C.V. Rapid communication: hypothalamic pro-opiomelanocortin mRNA is reduced by fasting and in ob/ob and db/db mice, but is stimulated by leptin. Diabetes 1998, 47:294-297.
-
(1998)
Diabetes
, vol.47
, pp. 294-297
-
-
Mizuno, T.M.1
Kleopoulos, S.P.2
Bergen, H.T.3
Roberts, J.L.4
Priest, C.A.5
Mobbs, C.V.6
-
135
-
-
0242300570
-
Transgenic neuronal expression of proopiomelanocortin attenuates fasting-induced hyperphagia and reverses metabolic impairments in leptin-deficient obese mice
-
Mizuno T.M., Kelly K., Pasinetti G.M., Roberts J.L., Mobbs C.V. Transgenic neuronal expression of proopiomelanocortin attenuates fasting-induced hyperphagia and reverses metabolic impairments in leptin-deficient obese mice. Diabetes 2003, 52:2675-2683.
-
(2003)
Diabetes
, vol.52
, pp. 2675-2683
-
-
Mizuno, T.M.1
Kelly, K.2
Pasinetti, G.M.3
Roberts, J.L.4
Mobbs, C.V.5
-
136
-
-
0006833534
-
Neurotoxic effects of estrogen, glucose, and glucocorticoids: neurohumoral hysteresis and its pathological consequences during aging
-
Mobbs C.V. Neurotoxic effects of estrogen, glucose, and glucocorticoids: neurohumoral hysteresis and its pathological consequences during aging. Rev. Biol. Res. Aging 1990, 4:201-228.
-
(1990)
Rev. Biol. Res. Aging
, vol.4
, pp. 201-228
-
-
Mobbs, C.V.1
-
137
-
-
0021746332
-
Reproductive senescence in female C57BL/6J mice: ovarian impairments and neuroendocrine impairments that are partially reversible and delayable by ovariectomy
-
Mobbs C.V., Gee D.M., Finch C.E. Reproductive senescence in female C57BL/6J mice: ovarian impairments and neuroendocrine impairments that are partially reversible and delayable by ovariectomy. Endocrinology 1984, 115:1653-1662.
-
(1984)
Endocrinology
, vol.115
, pp. 1653-1662
-
-
Mobbs, C.V.1
Gee, D.M.2
Finch, C.E.3
-
138
-
-
35348992350
-
Secrets of the lac operon. Glucose hysteresis as a mechanism in dietary restriction, aging and disease
-
Mobbs C.V., Mastaitis J.W., Zhang M., Isoda F., Cheng H., Yen K. Secrets of the lac operon. Glucose hysteresis as a mechanism in dietary restriction, aging and disease. Interdiscip. Top Gerontol. 2007, 35:39-68.
-
(2007)
Interdiscip. Top Gerontol.
, vol.35
, pp. 39-68
-
-
Mobbs, C.V.1
Mastaitis, J.W.2
Zhang, M.3
Isoda, F.4
Cheng, H.5
Yen, K.6
-
139
-
-
28144463727
-
Cytosolic action of thyroid hormone leads to induction of hypoxia-inducible factor-1alpha and glycolytic genes
-
Moeller L.C., Dumitrescu A.M., Refetoff S. Cytosolic action of thyroid hormone leads to induction of hypoxia-inducible factor-1alpha and glycolytic genes. Mol. Endocrinol. 2005, 19:2955-2963.
-
(2005)
Mol. Endocrinol.
, vol.19
, pp. 2955-2963
-
-
Moeller, L.C.1
Dumitrescu, A.M.2
Refetoff, S.3
-
140
-
-
0015993982
-
Hypoglycemia and body temperature
-
Molnar G.W., Read R.C. Hypoglycemia and body temperature. JAMA 1974, 227:916-921.
-
(1974)
JAMA
, vol.227
, pp. 916-921
-
-
Molnar, G.W.1
Read, R.C.2
-
141
-
-
0030878110
-
Congenital leptin deficiency is associated with severe early-onset obesity in humans
-
Montague C.T., Farooqi I.S., Whitehead J.P., Soos M.A., Rau H., Wareham N.J., Sewter C.P., Digby J.E., Mohammed S.N., Hurst J.A., Cheetham C.H., Earley A.R., Barnett A.H., Prins J.B., O'Rahilly S. Congenital leptin deficiency is associated with severe early-onset obesity in humans. Nature 1997, 387:903-908.
-
(1997)
Nature
, vol.387
, pp. 903-908
-
-
Montague, C.T.1
Farooqi, I.S.2
Whitehead, J.P.3
Soos, M.A.4
Rau, H.5
Wareham, N.J.6
Sewter, C.P.7
Digby, J.E.8
Mohammed, S.N.9
Hurst, J.A.10
Cheetham, C.H.11
Earley, A.R.12
Barnett, A.H.13
Prins, J.B.14
O'Rahilly, S.15
-
142
-
-
84873245416
-
Regulation of peripheral metabolism by substrate partitioning in the brain
-
in press
-
Moreno, C., Yang, L., Dacks, P.A., Isoda, F., Poplawski, M., Mobbs, C.V., in press. Regulation of peripheral metabolism by substrate partitioning in the brain. Endocrinol. Metab. Clin. N. Am. 42 (1).
-
Endocrinol. Metab. Clin. N. Am.
, vol.42
, Issue.1
-
-
Moreno, C.1
Yang, L.2
Dacks, P.A.3
Isoda, F.4
Poplawski, M.5
Mobbs, C.V.6
-
143
-
-
7244253081
-
Nrf2-Keap1 defines a physiologically important stress response mechanism
-
Motohashi H., Yamamoto M. Nrf2-Keap1 defines a physiologically important stress response mechanism. Trends Mol. Med. 2004, 10:549-557.
-
(2004)
Trends Mol. Med.
, vol.10
, pp. 549-557
-
-
Motohashi, H.1
Yamamoto, M.2
-
144
-
-
70149092727
-
Caloric restriction attenuates amyloid deposition in middle-aged dtg APP/PS1 mice
-
Mouton P.R., Chachich M.E., Quigley C., Spangler E., Ingram D.K. Caloric restriction attenuates amyloid deposition in middle-aged dtg APP/PS1 mice. Neurosci. Lett. 2009, 464:184-187.
-
(2009)
Neurosci. Lett.
, vol.464
, pp. 184-187
-
-
Mouton, P.R.1
Chachich, M.E.2
Quigley, C.3
Spangler, E.4
Ingram, D.K.5
-
145
-
-
0842331564
-
Decrease in glucose-stimulated insulin secretion with aging is independent of insulin action
-
Muzumdar R., Ma X., Atzmon G., Vuguin P., Yang X., Barzilai N. Decrease in glucose-stimulated insulin secretion with aging is independent of insulin action. Diabetes 2004, 53:441-446.
-
(2004)
Diabetes
, vol.53
, pp. 441-446
-
-
Muzumdar, R.1
Ma, X.2
Atzmon, G.3
Vuguin, P.4
Yang, X.5
Barzilai, N.6
-
146
-
-
0029939117
-
Reduction of glucose availability suppresses pulsatile luteinizing hormone release in female and male rats
-
Nagatani S., Bucholtz D.C., Murahashi K., Estacio M.A., Tsukamura H., Foster D.L., Maeda K.I. Reduction of glucose availability suppresses pulsatile luteinizing hormone release in female and male rats. Endocrinology 1996, 137:1166-1170.
-
(1996)
Endocrinology
, vol.137
, pp. 1166-1170
-
-
Nagatani, S.1
Bucholtz, D.C.2
Murahashi, K.3
Estacio, M.A.4
Tsukamura, H.5
Foster, D.L.6
Maeda, K.I.7
-
147
-
-
12944335299
-
DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells
-
Nasrin N., Ogg S., Cahill C.M., Biggs W., Nui S., Dore J., Calvo D., Shi Y., Ruvkun G., Alexander-Bridges M.C. DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells. Proc. Natl. Acad. Sci. USA 2000, 97:10412-10417.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 10412-10417
-
-
Nasrin, N.1
Ogg, S.2
Cahill, C.M.3
Biggs, W.4
Nui, S.5
Dore, J.6
Calvo, D.7
Shi, Y.8
Ruvkun, G.9
Alexander-Bridges, M.C.10
-
148
-
-
0014683812
-
Glucose and osmosensitive neurones of the rat hypothalamus
-
Oomura Y., Ono T., Ooyama H., Wayner M.J. Glucose and osmosensitive neurones of the rat hypothalamus. Nature 1969, 222:282-284.
-
(1969)
Nature
, vol.222
, pp. 282-284
-
-
Oomura, Y.1
Ono, T.2
Ooyama, H.3
Wayner, M.J.4
-
149
-
-
0023941926
-
Local cerebral glucose utilization in controlled graded levels of hyperglycemia in the conscious rat
-
Orzi F., Lucignani G., Dow-Edwards D., Namba H., Nehlig A., Patlak C.S., Pettigrew K., Schuier F., Sokoloff L. Local cerebral glucose utilization in controlled graded levels of hyperglycemia in the conscious rat. J. Cereb. Blood Flow Metab. 1988, 8:346-356.
-
(1988)
J. Cereb. Blood Flow Metab.
, vol.8
, pp. 346-356
-
-
Orzi, F.1
Lucignani, G.2
Dow-Edwards, D.3
Namba, H.4
Nehlig, A.5
Patlak, C.S.6
Pettigrew, K.7
Schuier, F.8
Sokoloff, L.9
-
150
-
-
84859173535
-
Repression of a potassium channel by nuclear hormone receptor and TGF-beta signaling modulates insulin signaling in Caenorhabditis elegans
-
Park D., Jones K.L., Lee H., Snutch T.P., Taubert S., Riddle D.L. Repression of a potassium channel by nuclear hormone receptor and TGF-beta signaling modulates insulin signaling in Caenorhabditis elegans. PLoS Genet. 2012, 8:e1002519.
-
(2012)
PLoS Genet.
, vol.8
-
-
Park, D.1
Jones, K.L.2
Lee, H.3
Snutch, T.P.4
Taubert, S.5
Riddle, D.L.6
-
151
-
-
84863011114
-
Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases
-
Park S.J., Ahmad F., Philp A., Baar K., Williams T., Luo H., Ke H., Rehmann H., Taussig R., Brown A.L., Kim M.K., Beaven M.A., Burgin A.B., Manganiello V., Chung J.H. Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases. Cell 2012, 148:421-433.
-
(2012)
Cell
, vol.148
, pp. 421-433
-
-
Park, S.J.1
Ahmad, F.2
Philp, A.3
Baar, K.4
Williams, T.5
Luo, H.6
Ke, H.7
Rehmann, H.8
Taussig, R.9
Brown, A.L.10
Kim, M.K.11
Beaven, M.A.12
Burgin, A.B.13
Manganiello, V.14
Chung, J.H.15
-
152
-
-
14644421534
-
Caloric restriction attenuates Abeta-deposition in Alzheimer transgenic models
-
Patel N.V., Gordon M.N., Connor K.E., Good R.A., Engelman R.W., Mason J., Morgan D.G., Morgan T.E., Finch C.E. Caloric restriction attenuates Abeta-deposition in Alzheimer transgenic models. Neurobiol. Aging 2005, 26:995-1000.
-
(2005)
Neurobiol. Aging
, vol.26
, pp. 995-1000
-
-
Patel, N.V.1
Gordon, M.N.2
Connor, K.E.3
Good, R.A.4
Engelman, R.W.5
Mason, J.6
Morgan, D.G.7
Morgan, T.E.8
Finch, C.E.9
-
153
-
-
38149068848
-
Monosodium glutamate-induced arcuate nucleus damage affects both natural torpor and 2DG-induced torpor-like hypothermia in Siberian hamsters
-
Pelz K.M., Routman D., Driscoll J.R., Kriegsfeld L.J., Dark J. Monosodium glutamate-induced arcuate nucleus damage affects both natural torpor and 2DG-induced torpor-like hypothermia in Siberian hamsters. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2008, 294:R255-R265.
-
(2008)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.294
-
-
Pelz, K.M.1
Routman, D.2
Driscoll, J.R.3
Kriegsfeld, L.J.4
Dark, J.5
-
154
-
-
69949091182
-
Is the oxidative stress theory of aging dead?
-
Perez V.I., Bokov A., Van Remmen H., Mele J., Ran Q., Ikeno Y., Richardson A. Is the oxidative stress theory of aging dead?. Biochim. Biophys. Acta 2009, 1790:1005-1014.
-
(2009)
Biochim. Biophys. Acta
, vol.1790
, pp. 1005-1014
-
-
Perez, V.I.1
Bokov, A.2
Van Remmen, H.3
Mele, J.4
Ran, Q.5
Ikeno, Y.6
Richardson, A.7
-
155
-
-
0030030186
-
Effect of adrenalectomy and corticosterone substitution on glucose and glycogen metabolism in rat brain
-
Plaschke K., Muller D., Hoyer S. Effect of adrenalectomy and corticosterone substitution on glucose and glycogen metabolism in rat brain. J. Neural. Transm. 1996, 103:89-100.
-
(1996)
J. Neural. Transm.
, vol.103
, pp. 89-100
-
-
Plaschke, K.1
Muller, D.2
Hoyer, S.3
-
156
-
-
77951760782
-
Carbon dioxide sensing modulates lifespan and physiology in Drosophila
-
Poon P.C., Kuo T.H., Linford N.J., Roman G., Pletcher S.D. Carbon dioxide sensing modulates lifespan and physiology in Drosophila. PLoS Biol. 2010, 8:e1000356.
-
(2010)
PLoS Biol.
, vol.8
-
-
Poon, P.C.1
Kuo, T.H.2
Linford, N.J.3
Roman, G.4
Pletcher, S.D.5
-
157
-
-
78049498595
-
Hypothalamic responses to fasting indicate metabolic reprogramming away from glycolysis toward lipid oxidation
-
Poplawski M.M., Mastaitis J.W., Yang X.J., Mobbs C.V. Hypothalamic responses to fasting indicate metabolic reprogramming away from glycolysis toward lipid oxidation. Endocrinology 2010, 151:5206-5217.
-
(2010)
Endocrinology
, vol.151
, pp. 5206-5217
-
-
Poplawski, M.M.1
Mastaitis, J.W.2
Yang, X.J.3
Mobbs, C.V.4
-
158
-
-
78751501163
-
Naloxone, but not valsartan, preserves responses to hypoglycemia after antecedent hypoglycemia: role of metabolic reprogramming in counterregulatory failure
-
Poplawski M.M., Mastaitis J.W., Mobbs C.V. Naloxone, but not valsartan, preserves responses to hypoglycemia after antecedent hypoglycemia: role of metabolic reprogramming in counterregulatory failure. Diabetes 2011, 60:39-46.
-
(2011)
Diabetes
, vol.60
, pp. 39-46
-
-
Poplawski, M.M.1
Mastaitis, J.W.2
Mobbs, C.V.3
-
159
-
-
30944458446
-
Extension of chronological life span in yeast by decreased TOR pathway signaling
-
Powers R.W., Kaeberlein M., Caldwell S.D., Kennedy B.K., Fields S. Extension of chronological life span in yeast by decreased TOR pathway signaling. Genes Dev. 2006, 20:174-184.
-
(2006)
Genes Dev.
, vol.20
, pp. 174-184
-
-
Powers, R.W.1
Kaeberlein, M.2
Caldwell, S.D.3
Kennedy, B.K.4
Fields, S.5
-
160
-
-
33846959101
-
Calorie restriction attenuates Alzheimer's disease type brain amyloidosis in Squirrel monkeys (Saimiri sciureus)
-
Qin W., Chachich M., Lane M., Roth G., Bryant M., de Cabo R., Ottinger M.A., Mattison J., Ingram D., Gandy S., Pasinetti G.M. Calorie restriction attenuates Alzheimer's disease type brain amyloidosis in Squirrel monkeys (Saimiri sciureus). J. Alzheimers Dis. 2006, 10:417-422.
-
(2006)
J. Alzheimers Dis.
, vol.10
, pp. 417-422
-
-
Qin, W.1
Chachich, M.2
Lane, M.3
Roth, G.4
Bryant, M.5
de Cabo, R.6
Ottinger, M.A.7
Mattison, J.8
Ingram, D.9
Gandy, S.10
Pasinetti, G.M.11
-
161
-
-
0025021084
-
Transplanted suprachiasmatic nucleus determines circadian period
-
Ralph M.R., Foster R.G., Davis F.C., Menaker M. Transplanted suprachiasmatic nucleus determines circadian period. Science 1990, 247:975-978.
-
(1990)
Science
, vol.247
, pp. 975-978
-
-
Ralph, M.R.1
Foster, R.G.2
Davis, F.C.3
Menaker, M.4
-
162
-
-
80051662211
-
Does hypothalamic SIRT1 regulate aging?
-
Ramadori G., Coppari R. Does hypothalamic SIRT1 regulate aging?. Aging (Albany, NY) 2011, 3:325-328.
-
(2011)
Aging (Albany, NY)
, vol.3
, pp. 325-328
-
-
Ramadori, G.1
Coppari, R.2
-
163
-
-
0037194790
-
Coordination of circadian timing in mammals
-
Reppert S.M., Weaver D.R. Coordination of circadian timing in mammals. Nature 2002, 418:935-941.
-
(2002)
Nature
, vol.418
, pp. 935-941
-
-
Reppert, S.M.1
Weaver, D.R.2
-
164
-
-
73649141006
-
Peroxisome proliferator-activated receptor-alpha control of lipid and glucose metabolism in human white adipocytes
-
Ribet C., Montastier E., Valle C., Bezaire V., Mazzucotelli A., Mairal A., Viguerie N., Langin D. Peroxisome proliferator-activated receptor-alpha control of lipid and glucose metabolism in human white adipocytes. Endocrinology 2010, 151:123-133.
-
(2010)
Endocrinology
, vol.151
, pp. 123-133
-
-
Ribet, C.1
Montastier, E.2
Valle, C.3
Bezaire, V.4
Mazzucotelli, A.5
Mairal, A.6
Viguerie, N.7
Langin, D.8
-
165
-
-
0038064168
-
Strain variation in the response of body temperature to dietary restriction
-
Rikke B.A., Yerg J.E., Battaglia M.E., Nagy T.R., Allison D.B., Johnson T.E. Strain variation in the response of body temperature to dietary restriction. Mech. Ageing Dev. 2003, 124:663-678.
-
(2003)
Mech. Ageing Dev.
, vol.124
, pp. 663-678
-
-
Rikke, B.A.1
Yerg, J.E.2
Battaglia, M.E.3
Nagy, T.R.4
Allison, D.B.5
Johnson, T.E.6
-
166
-
-
77955841569
-
Genetic dissection of dietary restriction in mice supports the metabolic efficiency model of life extension
-
Rikke B.A., Liao C.Y., McQueen M.B., Nelson J.F., Johnson T.E. Genetic dissection of dietary restriction in mice supports the metabolic efficiency model of life extension. Exp. Gerontol. 2010, 45:691-701.
-
(2010)
Exp. Gerontol.
, vol.45
, pp. 691-701
-
-
Rikke, B.A.1
Liao, C.Y.2
McQueen, M.B.3
Nelson, J.F.4
Johnson, T.E.5
-
167
-
-
0141857820
-
Glycolysis and glucose transporter 1 as markers of response to hormonal therapy in breast cancer
-
Rivenzon-Segal D., Boldin-Adamsky S., Seger D., Seger R., Degani H. Glycolysis and glucose transporter 1 as markers of response to hormonal therapy in breast cancer. Int. J. Cancer 2003, 107:177-182.
-
(2003)
Int. J. Cancer
, vol.107
, pp. 177-182
-
-
Rivenzon-Segal, D.1
Boldin-Adamsky, S.2
Seger, D.3
Seger, R.4
Degani, H.5
-
168
-
-
0031841713
-
Physiological significance of behavioral hypothermia in hypoglycemic frogs (Rana catesbeiana)
-
Rocha P.L., Branco L.G. Physiological significance of behavioral hypothermia in hypoglycemic frogs (Rana catesbeiana). Comp. Biochem. Physiol. A: Mol. Integr. Physiol. 1998, 119:957-961.
-
(1998)
Comp. Biochem. Physiol. A: Mol. Integr. Physiol.
, vol.119
, pp. 957-961
-
-
Rocha, P.L.1
Branco, L.G.2
-
169
-
-
0036085577
-
Selected contribution: ambient temperature for experiments in rats: a new method for determining the zone of thermal neutrality
-
Romanovsky A.A., Ivanov A.I., Shimansky Y.P. Selected contribution: ambient temperature for experiments in rats: a new method for determining the zone of thermal neutrality. J. Appl. Physiol. 2002, 92:2667-2679.
-
(2002)
J. Appl. Physiol.
, vol.92
, pp. 2667-2679
-
-
Romanovsky, A.A.1
Ivanov, A.I.2
Shimansky, Y.P.3
-
170
-
-
0031937707
-
Hyperphagia in children with craniopharyngioma is associated with hyperleptinaemia and a failure in the downregulation of appetite
-
Roth C., Wilken B., Hanefeld F., Schroter W., Leonhardt U. Hyperphagia in children with craniopharyngioma is associated with hyperleptinaemia and a failure in the downregulation of appetite. Eur. J. Endocrinol. 1998, 138:89-91.
-
(1998)
Eur. J. Endocrinol.
, vol.138
, pp. 89-91
-
-
Roth, C.1
Wilken, B.2
Hanefeld, F.3
Schroter, W.4
Leonhardt, U.5
-
171
-
-
0037008501
-
Biomarkers of caloric restriction may predict longevity in humans
-
Roth G.S., Lane M.A., Ingram D.K., Mattison J.A., Elahi D., Tobin J.D., Muller D., Metter E.J. Biomarkers of caloric restriction may predict longevity in humans. Science 2002, 297:811.
-
(2002)
Science
, vol.297
, pp. 811
-
-
Roth, G.S.1
Lane, M.A.2
Ingram, D.K.3
Mattison, J.A.4
Elahi, D.5
Tobin, J.D.6
Muller, D.7
Metter, E.J.8
-
172
-
-
0026503806
-
Feeding modulation by pentose and hexose analogues
-
Sakata T., Kurokawa M. Feeding modulation by pentose and hexose analogues. Am. J. Clin. Nutr. 1992, 55:272S-277S.
-
(1992)
Am. J. Clin. Nutr.
, vol.55
-
-
Sakata, T.1
Kurokawa, M.2
-
173
-
-
36248964713
-
Gene activities that mediate increased life span of C. elegans insulin-like signaling mutants
-
Samuelson A.V., Carr C.E., Ruvkun G. Gene activities that mediate increased life span of C. elegans insulin-like signaling mutants. Genes Dev. 2007, 21:2976-2994.
-
(2007)
Genes Dev.
, vol.21
, pp. 2976-2994
-
-
Samuelson, A.V.1
Carr, C.E.2
Ruvkun, G.3
-
174
-
-
79952535268
-
Sex- and age-specific differences in core body temperature of C57Bl/6 mice
-
Sanchez-Alavez M., Alboni S., Conti B. Sex- and age-specific differences in core body temperature of C57Bl/6 mice. Age (Dordr) 2011, 33:89-99.
-
(2011)
Age (Dordr)
, vol.33
, pp. 89-99
-
-
Sanchez-Alavez, M.1
Alboni, S.2
Conti, B.3
-
175
-
-
0022763667
-
The neuroendocrinology of stress and aging: the glucocorticoid cascade hypothesis
-
Sapolsky R.M., Krey L.C., McEwen B.S. The neuroendocrinology of stress and aging: the glucocorticoid cascade hypothesis. Endocr. Rev. 1986, 7:284-301.
-
(1986)
Endocr. Rev.
, vol.7
, pp. 284-301
-
-
Sapolsky, R.M.1
Krey, L.C.2
McEwen, B.S.3
-
176
-
-
77955344258
-
SIRT1 promotes the central adaptive response to diet restriction through activation of the dorsomedial and lateral nuclei of the hypothalamus
-
Satoh A., Brace C.S., Ben-Josef G., West T., Wozniak D.F., Holtzman D.M., Herzog E.D., Imai S. SIRT1 promotes the central adaptive response to diet restriction through activation of the dorsomedial and lateral nuclei of the hypothalamus. J. Neurosci. 2010, 30:10220-10232.
-
(2010)
J. Neurosci.
, vol.30
, pp. 10220-10232
-
-
Satoh, A.1
Brace, C.S.2
Ben-Josef, G.3
West, T.4
Wozniak, D.F.5
Holtzman, D.M.6
Herzog, E.D.7
Imai, S.8
-
177
-
-
63149163425
-
Adverse metabolic and cardiovascular consequences of circadian misalignment
-
Scheer F.A., Hilton M.F., Mantzoros C.S., Shea S.A. Adverse metabolic and cardiovascular consequences of circadian misalignment. Proc. Natl. Acad. Sci. USA 2009, 106:4453-4458.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 4453-4458
-
-
Scheer, F.A.1
Hilton, M.F.2
Mantzoros, C.S.3
Shea, S.A.4
-
178
-
-
77956026310
-
Dietary manipulation and caloric restriction in the development of mouse models relevant to neurological diseases
-
Schroeder J.E., Richardson J.C., Virley D.J. Dietary manipulation and caloric restriction in the development of mouse models relevant to neurological diseases. Biochim. Biophys. Acta 1802, 2010:840-846.
-
(1802)
Biochim. Biophys. Acta
, vol.2010
, pp. 840-846
-
-
Schroeder, J.E.1
Richardson, J.C.2
Virley, D.J.3
-
179
-
-
0036797511
-
Acute and prolonged effects of insulin-induced hypoglycemia on the pituitary-thyroid axis in humans
-
Schultes B., Oltmanns K.M., Kern W., Born J., Fehm H.L., Peters A. Acute and prolonged effects of insulin-induced hypoglycemia on the pituitary-thyroid axis in humans. Metabolism 2002, 51:1370-1374.
-
(2002)
Metabolism
, vol.51
, pp. 1370-1374
-
-
Schultes, B.1
Oltmanns, K.M.2
Kern, W.3
Born, J.4
Fehm, H.L.5
Peters, A.6
-
180
-
-
2542433123
-
Central nervous and metabolic effects of intranasally applied leptin
-
Schulz C., Paulus K., Lehnert H. Central nervous and metabolic effects of intranasally applied leptin. Endocrinology 2004, 145:2696-2701.
-
(2004)
Endocrinology
, vol.145
, pp. 2696-2701
-
-
Schulz, C.1
Paulus, K.2
Lehnert, H.3
-
181
-
-
34748850786
-
Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress
-
Schulz T.J., Zarse K., Voigt A., Urban N., Birringer M., Ristow M. Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress. Cell Metab. 2007, 6:280-293.
-
(2007)
Cell Metab.
, vol.6
, pp. 280-293
-
-
Schulz, T.J.1
Zarse, K.2
Voigt, A.3
Urban, N.4
Birringer, M.5
Ristow, M.6
-
182
-
-
84455191526
-
Intranasal leptin reduces appetite and induces weight loss in rats with diet-induced obesity (DIO)
-
Schulz C., Paulus K., Johren O., Lehnert H. Intranasal leptin reduces appetite and induces weight loss in rats with diet-induced obesity (DIO). Endocrinology 2012, 153:143-153.
-
(2012)
Endocrinology
, vol.153
, pp. 143-153
-
-
Schulz, C.1
Paulus, K.2
Johren, O.3
Lehnert, H.4
-
183
-
-
0346725865
-
Caloric restriction and insulin-like growth factors in aging and cancer
-
Sell C. Caloric restriction and insulin-like growth factors in aging and cancer. Horm. Metab. Res. 2003, 35:705-711.
-
(2003)
Horm. Metab. Res.
, vol.35
, pp. 705-711
-
-
Sell, C.1
-
184
-
-
27244461080
-
Corepressor CtBP1 interacts with and specifically inhibits CBP activity
-
Senyuk V., Sinha K.K., Nucifora G. Corepressor CtBP1 interacts with and specifically inhibits CBP activity. Arch. Biochem. Biophys. 2005, 441:168-173.
-
(2005)
Arch. Biochem. Biophys.
, vol.441
, pp. 168-173
-
-
Senyuk, V.1
Sinha, K.K.2
Nucifora, G.3
-
185
-
-
0026068012
-
Role of the hypothalamus in insulin-independent glucose uptake in peripheral tissues
-
Shimazu T., Sudo M., Minokoshi Y., Takahashi A. Role of the hypothalamus in insulin-independent glucose uptake in peripheral tissues. Brain Res. Bull. 1991, 27:501-504.
-
(1991)
Brain Res. Bull.
, vol.27
, pp. 501-504
-
-
Shimazu, T.1
Sudo, M.2
Minokoshi, Y.3
Takahashi, A.4
-
186
-
-
0037213724
-
Effects of caloric restriction on gene expression in the arcuate nucleus
-
Shimokawa I., Fukuyama T., Yanagihara-Outa K., Tomita M., Komatsu T., Higami Y., Tuchiya T., Chiba T., Yamaza Y. Effects of caloric restriction on gene expression in the arcuate nucleus. Neurobiol. Aging 2003, 24:117-123.
-
(2003)
Neurobiol. Aging
, vol.24
, pp. 117-123
-
-
Shimokawa, I.1
Fukuyama, T.2
Yanagihara-Outa, K.3
Tomita, M.4
Komatsu, T.5
Higami, Y.6
Tuchiya, T.7
Chiba, T.8
Yamaza, Y.9
-
187
-
-
22744450382
-
Toward a unified theory of caloric restriction and longevity regulation
-
Sinclair D.A. Toward a unified theory of caloric restriction and longevity regulation. Mech. Ageing Dev. 2005, 126:987-1002.
-
(2005)
Mech. Ageing Dev.
, vol.126
, pp. 987-1002
-
-
Sinclair, D.A.1
-
188
-
-
44649170501
-
Age- and calorie-independent life span extension from dietary restriction by bacterial deprivation in Caenorhabditis elegans
-
Smith E.D., Kaeberlein T.L., Lydum B.T., Sager J., Welton K.L., Kennedy B.K., Kaeberlein M. Age- and calorie-independent life span extension from dietary restriction by bacterial deprivation in Caenorhabditis elegans. BMC Dev. Biol. 2008, 8:49.
-
(2008)
BMC Dev. Biol.
, vol.8
, pp. 49
-
-
Smith, E.D.1
Kaeberlein, T.L.2
Lydum, B.T.3
Sager, J.4
Welton, K.L.5
Kennedy, B.K.6
Kaeberlein, M.7
-
189
-
-
80052089449
-
Long-term calorie restriction, but not endurance exercise, lowers core body temperature in humans
-
Soare A., Cangemi R., Omodei D., Holloszy J.O., Fontana L. Long-term calorie restriction, but not endurance exercise, lowers core body temperature in humans. Aging (Albany, NY) 2011, 3:374-379.
-
(2011)
Aging (Albany, NY)
, vol.3
, pp. 374-379
-
-
Soare, A.1
Cangemi, R.2
Omodei, D.3
Holloszy, J.O.4
Fontana, L.5
-
190
-
-
0035650534
-
Convergence of pre- and postsynaptic influences on glucosensing neurons in the ventromedial hypothalamic nucleus
-
Song Z., Levin B.E., McArdle J.J., Bakhos N., Routh V.H. Convergence of pre- and postsynaptic influences on glucosensing neurons in the ventromedial hypothalamic nucleus. Diabetes 2001, 50:2673-2681.
-
(2001)
Diabetes
, vol.50
, pp. 2673-2681
-
-
Song, Z.1
Levin, B.E.2
McArdle, J.J.3
Bakhos, N.4
Routh, V.H.5
-
191
-
-
43449138491
-
Dietary restriction suppresses proteotoxicity and enhances longevity by an hsf-1-dependent mechanism in Caenorhabditis elegans
-
Steinkraus K.A., Smith E.D., Davis C., Carr D., Pendergrass W.R., Sutphin G.L., Kennedy B.K., Kaeberlein M. Dietary restriction suppresses proteotoxicity and enhances longevity by an hsf-1-dependent mechanism in Caenorhabditis elegans. Aging Cell 2008, 7:394-404.
-
(2008)
Aging Cell
, vol.7
, pp. 394-404
-
-
Steinkraus, K.A.1
Smith, E.D.2
Davis, C.3
Carr, D.4
Pendergrass, W.R.5
Sutphin, G.L.6
Kennedy, B.K.7
Kaeberlein, M.8
-
192
-
-
84857127132
-
Glucose enhances leptin signaling through modulation of AMPK activity
-
Su H., Jiang L., Carter-Su C., Rui L. Glucose enhances leptin signaling through modulation of AMPK activity. PLoS One 2012, 7:e31636.
-
(2012)
PLoS One
, vol.7
-
-
Su, H.1
Jiang, L.2
Carter-Su, C.3
Rui, L.4
-
193
-
-
0025942149
-
Ventromedial hypothalamic stimulation enhances peripheral glucose uptake in anesthetized rats
-
Sudo M., Minokoshi Y., Shimazu T. Ventromedial hypothalamic stimulation enhances peripheral glucose uptake in anesthetized rats. Am. J. Physiol. 1991, 261:E298-E303.
-
(1991)
Am. J. Physiol.
, vol.261
-
-
Sudo, M.1
Minokoshi, Y.2
Shimazu, T.3
-
194
-
-
0020438383
-
Hypothalamic regulation of lipid metabolism in the rat: effect of hypothalamic stimulation on lipogenesis
-
Takahashi A., Shimazu T. Hypothalamic regulation of lipid metabolism in the rat: effect of hypothalamic stimulation on lipogenesis. J. Auton. Nerv. Syst. 1982, 6:225-235.
-
(1982)
J. Auton. Nerv. Syst.
, vol.6
, pp. 225-235
-
-
Takahashi, A.1
Shimazu, T.2
-
195
-
-
0027092801
-
Effects of ventromedial hypothalamic stimulation on glucose transport system in rat tissues
-
Takahashi A., Sudo M., Minokoshi Y., Shimazu T. Effects of ventromedial hypothalamic stimulation on glucose transport system in rat tissues. Am. J. Physiol. 1992, 263:R1228-E1234.
-
(1992)
Am. J. Physiol.
, vol.263
-
-
Takahashi, A.1
Sudo, M.2
Minokoshi, Y.3
Shimazu, T.4
-
196
-
-
0037053361
-
Overexpression and ribozyme-mediated targeting of transcriptional coactivators CREB-binding protein and p300 revealed their indispensable roles in adipocyte differentiation through the regulation of peroxisome proliferator-activated receptor gamma
-
Takahashi N., Kawada T., Yamamoto T., Goto T., Taimatsu A., Aoki N., Kawasaki H., Taira K., Yokoyama K.K., Kamei Y., Fushiki T. Overexpression and ribozyme-mediated targeting of transcriptional coactivators CREB-binding protein and p300 revealed their indispensable roles in adipocyte differentiation through the regulation of peroxisome proliferator-activated receptor gamma. J. Biol. Chem. 2002, 277:16906-16912.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 16906-16912
-
-
Takahashi, N.1
Kawada, T.2
Yamamoto, T.3
Goto, T.4
Taimatsu, A.5
Aoki, N.6
Kawasaki, H.7
Taira, K.8
Yokoyama, K.K.9
Kamei, Y.10
Fushiki, T.11
-
197
-
-
0023029760
-
Effect of vagotomy on serum insulin in rats with paraventricular or ventromedial hypothalamic lesions
-
Tokunaga K., Fukushima M., Kemnitz J.W., Bray G.A. Effect of vagotomy on serum insulin in rats with paraventricular or ventromedial hypothalamic lesions. Endocrinology 1986, 119:1708-1711.
-
(1986)
Endocrinology
, vol.119
, pp. 1708-1711
-
-
Tokunaga, K.1
Fukushima, M.2
Kemnitz, J.W.3
Bray, G.A.4
-
198
-
-
34247616021
-
Synaptic glutamate release by ventromedial hypothalamic neurons is part of the neurocircuitry that prevents hypoglycemia
-
Tong Q., Ye C., McCrimmon R.J., Dhillon H., Choi B., Kramer M.D., Yu J., Yang Z., Christiansen L.M., Lee C.E., Choi C.S., Zigman J.M., Shulman G.I., Sherwin R.S., Elmquist J.K., Lowell B.B. Synaptic glutamate release by ventromedial hypothalamic neurons is part of the neurocircuitry that prevents hypoglycemia. Cell Metab. 2007, 5:383-393.
-
(2007)
Cell Metab.
, vol.5
, pp. 383-393
-
-
Tong, Q.1
Ye, C.2
McCrimmon, R.J.3
Dhillon, H.4
Choi, B.5
Kramer, M.D.6
Yu, J.7
Yang, Z.8
Christiansen, L.M.9
Lee, C.E.10
Choi, C.S.11
Zigman, J.M.12
Shulman, G.I.13
Sherwin, R.S.14
Elmquist, J.K.15
Lowell, B.B.16
-
199
-
-
34247587220
-
Lifespan modification by glucose and methionine in Drosophila melanogaster fed a chemically defined diet
-
Troen A.M., French E.E., Roberts J.F., Selhub J., Ordovas J.M., Parnell L.D., Lai C.Q. Lifespan modification by glucose and methionine in Drosophila melanogaster fed a chemically defined diet. Age (Dordr) 2007, 29:29-39.
-
(2007)
Age (Dordr)
, vol.29
, pp. 29-39
-
-
Troen, A.M.1
French, E.E.2
Roberts, J.F.3
Selhub, J.4
Ordovas, J.M.5
Parnell, L.D.6
Lai, C.Q.7
-
200
-
-
0026673110
-
Dietary alteration in the rates of cancer and aging
-
Turturro A., Hart R. Dietary alteration in the rates of cancer and aging. Exp. Gerontol. 1992, 27:583-592.
-
(1992)
Exp. Gerontol.
, vol.27
, pp. 583-592
-
-
Turturro, A.1
Hart, R.2
-
201
-
-
41549111593
-
Collective and individual functions of leptin receptor modulated neurons controlling metabolism and ingestion
-
van de Wall E., Leshan R., Xu A.W., Balthasar N., Coppari R., Liu S.M., Jo Y.H., MacKenzie R.G., Allison D.B., Dun N.J., Elmquist J., Lowell B.B., Barsh G.S., de Luca C., Myers M.G., Schwartz G.J., Chua S.C. Collective and individual functions of leptin receptor modulated neurons controlling metabolism and ingestion. Endocrinology 2008, 149:1773-1785.
-
(2008)
Endocrinology
, vol.149
, pp. 1773-1785
-
-
van de Wall, E.1
Leshan, R.2
Xu, A.W.3
Balthasar, N.4
Coppari, R.5
Liu, S.M.6
Jo, Y.H.7
MacKenzie, R.G.8
Allison, D.B.9
Dun, N.J.10
Elmquist, J.11
Lowell, B.B.12
Barsh, G.S.13
de Luca, C.14
Myers, M.G.15
Schwartz, G.J.16
Chua, S.C.17
-
202
-
-
0642367846
-
Genetics: influence of TOR kinase on lifespan in C. elegans
-
Vellai T., Takacs-Vellai K., Zhang Y., Kovacs A.L., Orosz L., Muller F. Genetics: influence of TOR kinase on lifespan in C. elegans. Nature 2003, 426:620.
-
(2003)
Nature
, vol.426
, pp. 620
-
-
Vellai, T.1
Takacs-Vellai, K.2
Zhang, Y.3
Kovacs, A.L.4
Orosz, L.5
Muller, F.6
-
203
-
-
0025274187
-
Ventromedial hypothalamic lesions abolish compensatory reduction in energy expenditure to weight loss
-
Vilberg T.R., Keesey R.E. Ventromedial hypothalamic lesions abolish compensatory reduction in energy expenditure to weight loss. Am. J. Physiol. 1990, 258:R476-R480.
-
(1990)
Am. J. Physiol.
, vol.258
-
-
Vilberg, T.R.1
Keesey, R.E.2
-
204
-
-
0014538212
-
Alterations in soluble/insoluble collagen ratios in the annual fish, Cynolebias bellottii, in relation to age and environmental temperature
-
Walford R.L., Liu R.K., Troup G.M., Hsiu J. Alterations in soluble/insoluble collagen ratios in the annual fish, Cynolebias bellottii, in relation to age and environmental temperature. Exp. Gerontol. 1969, 4:103-109.
-
(1969)
Exp. Gerontol.
, vol.4
, pp. 103-109
-
-
Walford, R.L.1
Liu, R.K.2
Troup, G.M.3
Hsiu, J.4
-
205
-
-
20144386977
-
Caloric restriction attenuates beta-amyloid neuropathology in a mouse model of Alzheimer's disease
-
Wang J., Ho L., Qin W., Rocher A.B., Seror I., Humala N., Maniar K., Dolios G., Wang R., Hof P.R., Pasinetti G.M. Caloric restriction attenuates beta-amyloid neuropathology in a mouse model of Alzheimer's disease. FASEB J. 2005, 19:659-661.
-
(2005)
FASEB J.
, vol.19
, pp. 659-661
-
-
Wang, J.1
Ho, L.2
Qin, W.3
Rocher, A.B.4
Seror, I.5
Humala, N.6
Maniar, K.7
Dolios, G.8
Wang, R.9
Hof, P.R.10
Pasinetti, G.M.11
-
206
-
-
79952227187
-
2-Deoxy-d-glucose treatment of endothelial cells induces autophagy by reactive oxygen species-mediated activation of the AMP-activated protein kinase
-
Wang Q., Liang B., Shirwany N.A., Zou M.H. 2-Deoxy-d-glucose treatment of endothelial cells induces autophagy by reactive oxygen species-mediated activation of the AMP-activated protein kinase. PLoS One 2011, 6:e17234.
-
(2011)
PLoS One
, vol.6
-
-
Wang, Q.1
Liang, B.2
Shirwany, N.A.3
Zou, M.H.4
-
207
-
-
0030739927
-
Activity measures in rhesus monkeys on long-term calorie restriction
-
Weed J.L., Lane M.A., Roth G.S., Speer D.L., Ingram D.K. Activity measures in rhesus monkeys on long-term calorie restriction. Physiol. Behav. 1997, 62:97-103.
-
(1997)
Physiol. Behav.
, vol.62
, pp. 97-103
-
-
Weed, J.L.1
Lane, M.A.2
Roth, G.S.3
Speer, D.L.4
Ingram, D.K.5
-
208
-
-
0026768421
-
Effect of caloric restriction on age-associated cancers
-
Weindruch R. Effect of caloric restriction on age-associated cancers. Exp. Gerontol. 1992, 27:575-581.
-
(1992)
Exp. Gerontol.
, vol.27
, pp. 575-581
-
-
Weindruch, R.1
-
209
-
-
0020044308
-
Dietary restriction in mice beginning at 1 year of age: effect on life- span and spontaneous cancer incidence
-
Weindruch R., Walford R.L. Dietary restriction in mice beginning at 1 year of age: effect on life- span and spontaneous cancer incidence. Science 1982, 215:1415-1418.
-
(1982)
Science
, vol.215
, pp. 1415-1418
-
-
Weindruch, R.1
Walford, R.L.2
-
210
-
-
0018761281
-
Influence of controlled dietary restriction on immunologic function and aging
-
Weindruch R.H., Kristie J.A., Cheney K.E., Walford R.L. Influence of controlled dietary restriction on immunologic function and aging. Fed. Proc. 1979, 38:2007-2016.
-
(1979)
Fed. Proc.
, vol.38
, pp. 2007-2016
-
-
Weindruch, R.H.1
Kristie, J.A.2
Cheney, K.E.3
Walford, R.L.4
-
212
-
-
80053235435
-
Caloric restriction: powerful protection for the aging heart and vasculature
-
Weiss E.P., Fontana L. Caloric restriction: powerful protection for the aging heart and vasculature. Am. J. Physiol. Heart Circ. Physiol. 2011, 301:H1205-H1219.
-
(2011)
Am. J. Physiol. Heart Circ. Physiol.
, vol.301
-
-
Weiss, E.P.1
Fontana, L.2
-
213
-
-
64849086653
-
Alterations in oxygen consumption, respiratory quotient, and heat production in long-lived GHRKO and Ames dwarf mice, and short-lived bGH transgenic mice
-
Westbrook R., Bonkowski M.S., Strader A.D., Bartke A. Alterations in oxygen consumption, respiratory quotient, and heat production in long-lived GHRKO and Ames dwarf mice, and short-lived bGH transgenic mice. J. Gerontol. A: Biol. Sci. Med. Sci. 2009, 64:443-451.
-
(2009)
J. Gerontol. A: Biol. Sci. Med. Sci.
, vol.64
, pp. 443-451
-
-
Westbrook, R.1
Bonkowski, M.S.2
Strader, A.D.3
Bartke, A.4
-
214
-
-
49149129556
-
Calorie restriction ameliorates neurodegenerative phenotypes in forebrain-specific presenilin-1 and presenilin-2 double knockout mice
-
Wu P., Shen Q., Dong S., Xu Z., Tsien J.Z., Hu Y. Calorie restriction ameliorates neurodegenerative phenotypes in forebrain-specific presenilin-1 and presenilin-2 double knockout mice. Neurobiol. Aging 2008, 29:1502-1511.
-
(2008)
Neurobiol. Aging
, vol.29
, pp. 1502-1511
-
-
Wu, P.1
Shen, Q.2
Dong, S.3
Xu, Z.4
Tsien, J.Z.5
Hu, Y.6
-
215
-
-
70049103975
-
Systematic gene expression profile of hypothalamus in calorie-restricted mice implicates the involvement of mTOR signaling in neuroprotective activity
-
Wu P., Jiang C., Shen Q., Hu Y. Systematic gene expression profile of hypothalamus in calorie-restricted mice implicates the involvement of mTOR signaling in neuroprotective activity. Mech. Ageing Dev. 2009, 130:602-610.
-
(2009)
Mech. Ageing Dev.
, vol.130
, pp. 602-610
-
-
Wu, P.1
Jiang, C.2
Shen, Q.3
Hu, Y.4
-
216
-
-
0032829063
-
Hypothalamic glucose sensor: similarities to and differences from pancreatic beta-cell mechanisms
-
Yang X.J., Kow L.M., Funabashi T., Mobbs C.V. Hypothalamic glucose sensor: similarities to and differences from pancreatic beta-cell mechanisms. Diabetes 1999, 48:1763.
-
(1999)
Diabetes
, vol.48
, pp. 1763
-
-
Yang, X.J.1
Kow, L.M.2
Funabashi, T.3
Mobbs, C.V.4
-
217
-
-
0347360368
-
Metabolic pathways that mediate inhibition of hypothalamic neurons by glucose
-
Yang X.J., Kow L.M., Pfaff D.W., Mobbs C.V. Metabolic pathways that mediate inhibition of hypothalamic neurons by glucose. Diabetes 2004, 53:67-73.
-
(2004)
Diabetes
, vol.53
, pp. 67-73
-
-
Yang, X.J.1
Kow, L.M.2
Pfaff, D.W.3
Mobbs, C.V.4
-
218
-
-
56349163468
-
Dietary restriction and cold temperature both acutely reduce senescence in C. elegans
-
Yen, K., Mobbs, C.V., 2007. Dietary restriction and cold temperature both acutely reduce senescence in C. elegans. Open Longev. Sci. 1, 8-13.
-
(2007)
Open Longev. Sci.
, vol.1
, pp. 8-13
-
-
Yen, K.1
Mobbs, C.V.2
-
219
-
-
59049088086
-
SOD isoforms play no role in lifespan in ad lib or dietary restricted conditions, but mutational inactivation of SOD-1 reduces life extension by cold
-
Yen K., Patel H.B., Lublin A.L., Mobbs C.V. SOD isoforms play no role in lifespan in ad lib or dietary restricted conditions, but mutational inactivation of SOD-1 reduces life extension by cold. Mech. Ageing Dev. 2009, 130:173-178.
-
(2009)
Mech. Ageing Dev.
, vol.130
, pp. 173-178
-
-
Yen, K.1
Patel, H.B.2
Lublin, A.L.3
Mobbs, C.V.4
-
220
-
-
11144353910
-
PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues
-
Yoo S.H., Yamazaki S., Lowrey P.L., Shimomura K., Ko C.H., Buhr E.D., Siepka S.M., Hong H.K., Oh W.J., Yoo O.J., Menaker M., Takahashi J.S. PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues. Proc. Natl. Acad. Sci. USA 2004, 101:5339-5346.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 5339-5346
-
-
Yoo, S.H.1
Yamazaki, S.2
Lowrey, P.L.3
Shimomura, K.4
Ko, C.H.5
Buhr, E.D.6
Siepka, S.M.7
Hong, H.K.8
Oh, W.J.9
Yoo, O.J.10
Menaker, M.11
Takahashi, J.S.12
-
221
-
-
33846505019
-
Metabolic regulation of SIRT1 transcription via a HIC1:CtBP corepressor complex
-
Zhang Q., Wang S.Y., Fleuriel C., Leprince D., Rocheleau J.V., Piston D.W., Goodman R.H. Metabolic regulation of SIRT1 transcription via a HIC1:CtBP corepressor complex. Proc. Natl. Acad. Sci. USA 2007, 104:829-833.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 829-833
-
-
Zhang, Q.1
Wang, S.Y.2
Fleuriel, C.3
Leprince, D.4
Rocheleau, J.V.5
Piston, D.W.6
Goodman, R.H.7
-
222
-
-
72949109772
-
Role of CBP and SATB-1 in aging, dietary restriction, and insulin-like signaling
-
Zhang M., Poplawski M., Yen K., Cheng H., Bloss E., Zhu X., Patel H., Mobbs C.V. Role of CBP and SATB-1 in aging, dietary restriction, and insulin-like signaling. PLoS Biol. 2009, 7:e1000245.
-
(2009)
PLoS Biol.
, vol.7
-
-
Zhang, M.1
Poplawski, M.2
Yen, K.3
Cheng, H.4
Bloss, E.5
Zhu, X.6
Patel, H.7
Mobbs, C.V.8
-
223
-
-
0033581321
-
Dietary restriction protects hippocampal neurons against the death-promoting action of a presenilin-1 mutation
-
Zhu H., Guo Q., Mattson M.P. Dietary restriction protects hippocampal neurons against the death-promoting action of a presenilin-1 mutation. Brain Res. 1999, 842:224-229.
-
(1999)
Brain Res.
, vol.842
, pp. 224-229
-
-
Zhu, H.1
Guo, Q.2
Mattson, M.P.3
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