메뉴 건너뛰기




Volumn 56, Issue 4, 2007, Pages 1120-1126

ATP-sensitive K+ channels regulate the release of GABA in the ventromedial hypothalamus during hypoglycemia

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; ADRENALIN; BICUCULLINE METHIODIDE; DIAZOXIDE; GLIBENCLAMIDE; GLUCAGON; GLUCOSE; MUSCIMOL;

EID: 34047114378     PISSN: 00121797     EISSN: 00121797     Source Type: Journal    
DOI: 10.2337/db06-1102     Document Type: Article
Times cited : (67)

References (49)
  • 1
    • 0028817815 scopus 로고    scopus 로고
    • U.K. Prospective Diabetes Study Group: U.K. Prospective Diabetes Study 16: overview of 6 years' therapy of type II diabetes: a progressive disease. Diabetes 44:1249 -1258, 1995
    • U.K. Prospective Diabetes Study Group: U.K. Prospective Diabetes Study 16: overview of 6 years' therapy of type II diabetes: a progressive disease. Diabetes 44:1249 -1258, 1995
  • 2
    • 0031006603 scopus 로고    scopus 로고
    • Hypoglycemia in the Diabetes Control and Complications Trial
    • The Diabetes Control and Complications Trial Research Group
    • The Diabetes Control and Complications Trial Research Group: Hypoglycemia in the Diabetes Control and Complications Trial. Diabetes 46:271-286, 1997
    • (1997) Diabetes , vol.46 , pp. 271-286
  • 3
    • 0003010451 scopus 로고    scopus 로고
    • Hypoglycemia in insulin-dependent diabetes mellitus: Interplay of insulin excess and comprised glucose counterregulation
    • Porte D Jr, Sherwin RS, Eds. Stamford, Connecticut, Appleton & Lange
    • Cryer PE, Gerich JE: Hypoglycemia in insulin-dependent diabetes mellitus: interplay of insulin excess and comprised glucose counterregulation. In Ellenberg and Rifkin's Diabetes Mellitus. Porte D Jr, Sherwin RS, Eds. Stamford, Connecticut, Appleton & Lange, 1997, p. 745-760
    • (1997) Ellenberg and Rifkin's Diabetes Mellitus , pp. 745-760
    • Cryer, P.E.1    Gerich, J.E.2
  • 4
    • 0033049682 scopus 로고    scopus 로고
    • Chronic hypoglycemia and diabetes impair counterregulation induced by localized 2-deoxy-glucose perfusion of the ventromedial hypothalamus in rats
    • Borg MA, Borg WP, Tamborlane WV, Brines ML, Shulman GI, Sherwin RS: Chronic hypoglycemia and diabetes impair counterregulation induced by localized 2-deoxy-glucose perfusion of the ventromedial hypothalamus in rats. Diabetes 48:584 -587, 1999
    • (1999) Diabetes , vol.48 , pp. 584-587
    • Borg, M.A.1    Borg, W.P.2    Tamborlane, W.V.3    Brines, M.L.4    Shulman, G.I.5    Sherwin, R.S.6
  • 5
    • 0028296222 scopus 로고
    • Ventromedial hypothalamic lesions in rats suppress counterregulatory responses to hypoglycemia
    • Borg WP, During MJ, Sherwin RS, Borg MA, Brines ML, Shulman GI: Ventromedial hypothalamic lesions in rats suppress counterregulatory responses to hypoglycemia. J Clin Invest 93:1677-1682, 1994
    • (1994) J Clin Invest , vol.93 , pp. 1677-1682
    • Borg, W.P.1    During, M.J.2    Sherwin, R.S.3    Borg, M.A.4    Brines, M.L.5    Shulman, G.I.6
  • 6
    • 0028931891 scopus 로고
    • Local ventromedial hypothalamus glucopenia triggers counterregulatory hormone release
    • Borg WP, Sherwin RS, During MJ, Borg MA, Shulman GI: Local ventromedial hypothalamus glucopenia triggers counterregulatory hormone release. Diabetes 44:180 -184, 1995
    • (1995) Diabetes , vol.44 , pp. 180-184
    • Borg, W.P.1    Sherwin, R.S.2    During, M.J.3    Borg, M.A.4    Shulman, G.I.5
  • 7
    • 0031049045 scopus 로고    scopus 로고
    • Intracarotid glucose selectively increases Fos-like immunoreactivity in paraventricular, ventromedial and dorsomedial nuclei neurons
    • Dunn-Meynell AA, Govek E, Levin BE: Intracarotid glucose selectively increases Fos-like immunoreactivity in paraventricular, ventromedial and dorsomedial nuclei neurons. Brain Res 748:100 -106, 1997
    • (1997) Brain Res , vol.748 , pp. 100-106
    • Dunn-Meynell, A.A.1    Govek, E.2    Levin, B.E.3
  • 9
    • 0014683812 scopus 로고
    • Glucose and osmosensitive neurones of the rat hypothalamus
    • Oomura Y, Ono T, Ooyama H, Wayner MJ: Glucose and osmosensitive neurones of the rat hypothalamus. Nature 222:282-284, 1969
    • (1969) Nature , vol.222 , pp. 282-284
    • Oomura, Y.1    Ono, T.2    Ooyama, H.3    Wayner, M.J.4
  • 10
    • 0035187234 scopus 로고    scopus 로고
    • Effects of lactate on glucose-sensing neurons in the solitary tract nucleus
    • Himmi T, Perrin J, Dallaporta M, Orsini JC: Effects of lactate on glucose-sensing neurons in the solitary tract nucleus. Physiol Behav 74:391-397, 2001
    • (2001) Physiol Behav , vol.74 , pp. 391-397
    • Himmi, T.1    Perrin, J.2    Dallaporta, M.3    Orsini, J.C.4
  • 11
    • 0034463846 scopus 로고    scopus 로고
    • Localization of glucokinase-like immunoreactivity in the rat lower brain stem: For possible location of brain glucose-sensing mechanisms
    • Maekawa F, Toyoda Y, Torii N, Miwa I, Thompson RC, Foster DL, Tsukahara S, Tsukamura H, Maeda K: Localization of glucokinase-like immunoreactivity in the rat lower brain stem: for possible location of brain glucose-sensing mechanisms. Endocrinology 141:375-384, 2000
    • (2000) Endocrinology , vol.141 , pp. 375-384
    • Maekawa, F.1    Toyoda, Y.2    Torii, N.3    Miwa, I.4    Thompson, R.C.5    Foster, D.L.6    Tsukahara, S.7    Tsukamura, H.8    Maeda, K.9
  • 12
    • 0033761682 scopus 로고    scopus 로고
    • Repeated 2-deoxy-D-glucose-induced glucoprivation attenuates Fos expression and glucoregulatory responses during subsequent glucoprivation
    • Sanders NM, Ritter S: Repeated 2-deoxy-D-glucose-induced glucoprivation attenuates Fos expression and glucoregulatory responses during subsequent glucoprivation. Diabetes 49:1865-1874, 2000
    • (2000) Diabetes , vol.49 , pp. 1865-1874
    • Sanders, N.M.1    Ritter, S.2
  • 13
    • 0030851022 scopus 로고    scopus 로고
    • Novel glucosensor for hypoglycemic detection localized to the portal vein
    • Hevener AL, Bergman RN, Donovan CM: Novel glucosensor for hypoglycemic detection localized to the portal vein. Diabetes 46:1521-1525, 1997
    • (1997) Diabetes , vol.46 , pp. 1521-1525
    • Hevener, A.L.1    Bergman, R.N.2    Donovan, C.M.3
  • 14
    • 0033957338 scopus 로고    scopus 로고
    • Portal vein afferents are critical for the sympathoadrenal response to hypoglycemia
    • Hevener AL, Bergman RN, Donovan CM: Portal vein afferents are critical for the sympathoadrenal response to hypoglycemia. Diabetes 49:8 -12, 2000
    • (2000) Diabetes , vol.49 , pp. 8-12
    • Hevener, A.L.1    Bergman, R.N.2    Donovan, C.M.3
  • 15
    • 0035142148 scopus 로고    scopus 로고
    • Hypoglycemic detection does not occur in the hepatic artery or liver: Findings consistent with a portal vein glucosensor locus
    • Hevener AL, Bergman RN, Donovan CM: Hypoglycemic detection does not occur in the hepatic artery or liver: findings consistent with a portal vein glucosensor locus. Diabetes 50:399-403, 2001
    • (2001) Diabetes , vol.50 , pp. 399-403
    • Hevener, A.L.1    Bergman, R.N.2    Donovan, C.M.3
  • 16
    • 0025186956 scopus 로고
    • Tolbutamide excites rat glucoreceptive ventromedial hypothalamic neurones by indirect inhibition of ATP-K+ channels
    • Ashford ML, Boden PR, Treherne JM: Tolbutamide excites rat glucoreceptive ventromedial hypothalamic neurones by indirect inhibition of ATP-K+ channels. Br J Pharmacol 101:531-540, 1990
    • (1990) Br J Pharmacol , vol.101 , pp. 531-540
    • Ashford, M.L.1    Boden, P.R.2    Treherne, J.M.3
  • 17
    • 0031038124 scopus 로고    scopus 로고
    • Local ventromedial hypothalamus glucose perfusion blocks counterregulation during systemic hypoglycemia in awake rats
    • Borg MA, Sherwin RS, Borg WP, Tamborlane WV, Shulman GI: Local ventromedial hypothalamus glucose perfusion blocks counterregulation during systemic hypoglycemia in awake rats. J Clin Invest 99:361-365, 1997
    • (1997) J Clin Invest , vol.99 , pp. 361-365
    • Borg, M.A.1    Sherwin, R.S.2    Borg, W.P.3    Tamborlane, W.V.4    Shulman, G.I.5
  • 18
    • 1442276966 scopus 로고    scopus 로고
    • Physiological and molecular characteristics of rat hypothalamic ventromedial nucleus glucosensing neurons
    • Kang L, Routh VH, Kuzhikandathil EV, Gaspers LD, Levin BE: Physiological and molecular characteristics of rat hypothalamic ventromedial nucleus glucosensing neurons. Diabetes 53:549 -559, 2004
    • (2004) Diabetes , vol.53 , pp. 549-559
    • Kang, L.1    Routh, V.H.2    Kuzhikandathil, E.V.3    Gaspers, L.D.4    Levin, B.E.5
  • 19
    • 0141613642 scopus 로고    scopus 로고
    • Glucosensing neurons in the ventromedial hypothalamic nucleus (VMN) and hypoglycemia-associated autonomic failure (HAAF)
    • Routh VH: Glucosensing neurons in the ventromedial hypothalamic nucleus (VMN) and hypoglycemia-associated autonomic failure (HAAF). Diabete Metab Res Rev 19:348 -356, 2003
    • (2003) Diabete Metab Res Rev , vol.19 , pp. 348-356
    • Routh, V.H.1
  • 20
    • 0035650534 scopus 로고    scopus 로고
    • Convergence of pre- and postsynaptic influences on glucosensing neurons in the ventromedial hypothalamic nucleus
    • Song Z, Levin BE, McArdle JJ, Bakhos N, Routh VH: Convergence of pre- and postsynaptic influences on glucosensing neurons in the ventromedial hypothalamic nucleus. Diabetes 50:2673-2681, 2001
    • (2001) Diabetes , vol.50 , pp. 2673-2681
    • Song, Z.1    Levin, B.E.2    McArdle, J.J.3    Bakhos, N.4    Routh, V.H.5
  • 21
    • 0037306308 scopus 로고    scopus 로고
    • Physiological and pathophysiological roles of ATP-sensitive K+ channels
    • Seino S, Miki T: Physiological and pathophysiological roles of ATP-sensitive K+ channels. Prog Biophys Mol Biol 81:133-176, 2003
    • (2003) Prog Biophys Mol Biol , vol.81 , pp. 133-176
    • Seino, S.1    Miki, T.2
  • 22
    • 0033037098 scopus 로고    scopus 로고
    • ATP-sensitive potassium channels: A model of heteromultimeric potassium channel/receptor assemblies
    • Seino S: ATP-sensitive potassium channels: a model of heteromultimeric potassium channel/receptor assemblies. Annu Rev Physiol 61:337-362, 1999
    • (1999) Annu Rev Physiol , vol.61 , pp. 337-362
    • Seino, S.1
  • 23
    • 0023914251 scopus 로고
    • ATP-sensitive K+ channels in pancreatic beta-cells: Spare-channel hypothesis
    • Cook DL, Satin LS, Ashford ML, Hales CN: ATP-sensitive K+ channels in pancreatic beta-cells: spare-channel hypothesis. Diabetes 37:495- 498, 1988
    • (1988) Diabetes , vol.37 , pp. 495-498
    • Cook, D.L.1    Satin, L.S.2    Ashford, M.L.3    Hales, C.N.4
  • 24
    • 0022467904 scopus 로고
    • Pancreatic islet glucose metabolism and regulation of insulin secretion
    • Meglasson MD, Matschinsky FM: Pancreatic islet glucose metabolism and regulation of insulin secretion. Diabete Metab Rev 2:163-214, 1986
    • (1986) Diabete Metab Rev , vol.2 , pp. 163-214
    • Meglasson, M.D.1    Matschinsky, F.M.2
  • 25
    • 0030614567 scopus 로고    scopus 로고
    • Low-affinity sulfonylurea binding sites reside on neuronal cell bodies in the brain
    • Dunn-Meynell AA, Routh VH, McArdle JJ, Levin BE: Low-affinity sulfonylurea binding sites reside on neuronal cell bodies in the brain. Brain Res 745:1-9, 1997
    • (1997) Brain Res , vol.745 , pp. 1-9
    • Dunn-Meynell, A.A.1    Routh, V.H.2    McArdle, J.J.3    Levin, B.E.4
  • 26
    • 0032517821 scopus 로고    scopus 로고
    • Distribution and phenotype of neurons containing the ATP-sensitive K+ channel in rat brain
    • Dunn-Meynell AA, Rawson NE, Levin BE: Distribution and phenotype of neurons containing the ATP-sensitive K+ channel in rat brain. Brain Res 814:41-54, 1998
    • (1998) Brain Res , vol.814 , pp. 41-54
    • Dunn-Meynell, A.A.1    Rawson, N.E.2    Levin, B.E.3
  • 27
    • 0026677684 scopus 로고
    • Identification of an ATP-sensitive K+ channel in rat cultured cortical neurons
    • Ohno-Shosaku T, Yamamoto C: Identification of an ATP-sensitive K+ channel in rat cultured cortical neurons. Pflugers Arch 422:260 -266, 1992
    • (1992) Pflugers Arch , vol.422 , pp. 260-266
    • Ohno-Shosaku, T.1    Yamamoto, C.2
  • 28
    • 0029013644 scopus 로고
    • Metabolic inhibition and low internal ATP activate K-ATP channels in rat dopaminergic substantia nigra neurones
    • Roper J, Ashcroft FM: Metabolic inhibition and low internal ATP activate K-ATP channels in rat dopaminergic substantia nigra neurones. Pflugers Arch 430:44 -54, 1995
    • (1995) Pflugers Arch , vol.430 , pp. 44-54
    • Roper, J.1    Ashcroft, F.M.2
  • 29
    • 0033556338 scopus 로고    scopus 로고
    • Cell-type specific expression of ATP-sensitive potassium channels in the rat hippocampus
    • Zawar C, Plant TD, Schirra C, Konnerth A, Neumcke B: Cell-type specific expression of ATP-sensitive potassium channels in the rat hippocampus. J Physiol 514:327-341, 1999
    • (1999) J Physiol , vol.514 , pp. 327-341
    • Zawar, C.1    Plant, T.D.2    Schirra, C.3    Konnerth, A.4    Neumcke, B.5
  • 30
    • 0033988307 scopus 로고    scopus 로고
    • Involvement of adenosine triphosphate-sensitive K+ channels in glucose-sensing in the rat solitary tract nucleus
    • Dallaporta M, Perrin J, Orsini JC: Involvement of adenosine triphosphate-sensitive K+ channels in glucose-sensing in the rat solitary tract nucleus. Neurosci Lett 278:77- 80, 2000
    • (2000) Neurosci Lett , vol.278 , pp. 77-80
    • Dallaporta, M.1    Perrin, J.2    Orsini, J.C.3
  • 31
    • 0031440266 scopus 로고    scopus 로고
    • Leptin inhibits hypothalamic neurons by activation of ATP-sensitive potassium channels
    • Spanswick D, Smith MA, Groppi VE, Logan SD, Ashford ML: Leptin inhibits hypothalamic neurons by activation of ATP-sensitive potassium channels. Nature 390:521-525, 1997
    • (1997) Nature , vol.390 , pp. 521-525
    • Spanswick, D.1    Smith, M.A.2    Groppi, V.E.3    Logan, S.D.4    Ashford, M.L.5
  • 32
    • 0032829063 scopus 로고    scopus 로고
    • Hypothalamic glucose sensor: Similarities to and differences from pancreatic β-cell mechanisms
    • Yang XJ, Kow LM, Funabashi T, Mobbs CV: Hypothalamic glucose sensor: similarities to and differences from pancreatic β-cell mechanisms. Diabetes 48:1763-1772, 1999
    • (1999) Diabetes , vol.48 , pp. 1763-1772
    • Yang, X.J.1    Kow, L.M.2    Funabashi, T.3    Mobbs, C.V.4
  • 34
    • 4644298411 scopus 로고    scopus 로고
    • Hypothalamic ATP-sensitive K + channels play a key role in sensing hypoglycemia and triggering counterregulatory epinephrine and glucagon responses
    • Evans ML, McCrimmon RJ, Flanagan DE, Keshavarz T, Fan X, McNay EC, Jacob RJ, Sherwin RS: Hypothalamic ATP-sensitive K + channels play a key role in sensing hypoglycemia and triggering counterregulatory epinephrine and glucagon responses. Diabetes 53:2542-2551, 2004
    • (2004) Diabetes , vol.53 , pp. 2542-2551
    • Evans, M.L.1    McCrimmon, R.J.2    Flanagan, D.E.3    Keshavarz, T.4    Fan, X.5    McNay, E.C.6    Jacob, R.J.7    Sherwin, R.S.8
  • 35
    • 33644696261 scopus 로고    scopus 로고
    • Activation of ATP-sensitive K+ channels in the ventromedial hypothalamus amplifies counterregulatory hormone responses to hypoglycemia in normal and recurrently hypoglycemic rats
    • McCrimmon RJ, Evans ML, Fan X, McNay EC, Chan O, Ding Y, Zhu W, Gram DX, Sherwin RS: Activation of ATP-sensitive K+ channels in the ventromedial hypothalamus amplifies counterregulatory hormone responses to hypoglycemia in normal and recurrently hypoglycemic rats. Diabetes 54:3169 -3174, 2005
    • (2005) Diabetes , vol.54 , pp. 3169-3174
    • McCrimmon, R.J.1    Evans, M.L.2    Fan, X.3    McNay, E.C.4    Chan, O.5    Ding, Y.6    Zhu, W.7    Gram, D.X.8    Sherwin, R.S.9
  • 36
    • 33745327159 scopus 로고    scopus 로고
    • Blockade of GABAA receptors in the ventromedial hypothalamus further stimulates glucagon and sympathoadrenal but not the hypothalamo-pituitary-adrenal response to hypoglycemia
    • Chan O, Zhu W, Ding Y, McCrimmon RJ, Sherwin RS: Blockade of GABAA receptors in the ventromedial hypothalamus further stimulates glucagon and sympathoadrenal but not the hypothalamo-pituitary-adrenal response to hypoglycemia. Diabetes 55:1080 -1087, 2006
    • (2006) Diabetes , vol.55 , pp. 1080-1087
    • Chan, O.1    Zhu, W.2    Ding, Y.3    McCrimmon, R.J.4    Sherwin, R.S.5
  • 37
    • 0346365506 scopus 로고    scopus 로고
    • From artificial cerebro-spinal fluid (aCSF) to artificial extracellular fluid (aECF): Microdialysis perfusate composition effects on in vivo brain ECF glucose measurements
    • McNay EC, Sherwin RS: From artificial cerebro-spinal fluid (aCSF) to artificial extracellular fluid (aECF): microdialysis perfusate composition effects on in vivo brain ECF glucose measurements. J Neurosci Methods 132:35- 43, 2004
    • (2004) J Neurosci Methods , vol.132 , pp. 35-43
    • McNay, E.C.1    Sherwin, R.S.2
  • 38
  • 39
    • 0024835944 scopus 로고
    • The use of a cell-free perfusate in the perfused rat hindquarter: Methodological concerns
    • McDermott JC, Hutber A, Tan MH, Bonen A: The use of a cell-free perfusate in the perfused rat hindquarter: methodological concerns. Can J Physiol Pharmacol 67:1450 -1454, 1989
    • (1989) Can J Physiol Pharmacol , vol.67 , pp. 1450-1454
    • McDermott, J.C.1    Hutber, A.2    Tan, M.H.3    Bonen, A.4
  • 40
    • 3242811250 scopus 로고    scopus 로고
    • Potential role for AMP-activated protein kinase in hypoglycemia sensing in the ventromedial hypothalamus
    • McCrimmon RJ, Fan X, Ding Y, Zhu W, Jacob RJ, Sherwin RS: Potential role for AMP-activated protein kinase in hypoglycemia sensing in the ventromedial hypothalamus. Diabetes 53:1953-1958, 2004
    • (2004) Diabetes , vol.53 , pp. 1953-1958
    • McCrimmon, R.J.1    Fan, X.2    Ding, Y.3    Zhu, W.4    Jacob, R.J.5    Sherwin, R.S.6
  • 41
    • 0024383110 scopus 로고
    • Increased GABA shunt activity in VMN of three hyperphagic rat models
    • Beverly JL, Martin RJ: Increased GABA shunt activity in VMN of three hyperphagic rat models. Am J Physiol 256:R1225-R1231, 1989
    • (1989) Am J Physiol , vol.256
    • Beverly, J.L.1    Martin, R.J.2
  • 43
    • 0025164846 scopus 로고
    • Glucose, sulfonylureas, and neurotransmitter release: Role of ATP-sensitive K+ channels
    • Amoroso S, Schmid-Antomarchi H, Fosset M, Lazdunski M: Glucose, sulfonylureas, and neurotransmitter release: role of ATP-sensitive K+ channels. Science 247:852- 854, 1990
    • (1990) Science , vol.247 , pp. 852-854
    • Amoroso, S.1    Schmid-Antomarchi, H.2    Fosset, M.3    Lazdunski, M.4
  • 45
    • 0028951455 scopus 로고
    • Glucose modulates rat substantia nigra GABA release in vivo via ATP-sensitive potassium channels
    • During MJ, Leone P, Davis KE, Kerr D, Sherwin RS: Glucose modulates rat substantia nigra GABA release in vivo via ATP-sensitive potassium channels. J Clin Invest 95:2403-2408, 1995
    • (1995) J Clin Invest , vol.95 , pp. 2403-2408
    • During, M.J.1    Leone, P.2    Davis, K.E.3    Kerr, D.4    Sherwin, R.S.5
  • 46
    • 0028845455 scopus 로고
    • Alterations in extracellular GABA in the ventral hypothalamus of rats in response to acute glucoprivation
    • Beverly JL, Beverly MF, Meguid MM: Alterations in extracellular GABA in the ventral hypothalamus of rats in response to acute glucoprivation. Am J Physiol 269:R1174-R1178, 1995
    • (1995) Am J Physiol , vol.269
    • Beverly, J.L.1    Beverly, M.F.2    Meguid, M.M.3
  • 49
    • 0030967891 scopus 로고    scopus 로고
    • Microdialysis study of modification of hypothalamic neurotransmitters in streptozotocin-diabetic rats
    • Ohtani N, Ohta M, Sugano T: Microdialysis study of modification of hypothalamic neurotransmitters in streptozotocin-diabetic rats. J Neurochem 69:1622-1628, 1997
    • (1997) J Neurochem , vol.69 , pp. 1622-1628
    • Ohtani, N.1    Ohta, M.2    Sugano, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.