-
1
-
-
0001502793
-
Carbohydrate metabolism
-
Bethesda, MD, American Physiology Society
-
Halter JB; Carbohydrate metabolism. In Handbook of Physiology: Aging. Bethesda, MD, American Physiology Society, 1995, p. 119-145
-
(1995)
Handbook of Physiology: Aging
, pp. 119-145
-
-
Halter, J.B.1
-
2
-
-
0031897103
-
Prevalence of diabetes, impaired fasting glucose and impaired glucose tolerance in U.S. adults: The Third Nation Health and Nutrition Examination Survey, 1988-1994
-
Harris MI, Flegal FM, Cowie CC, Eberhardt MS, Golstein DE, Little RR, Weidmeyer HS, Bryd-Holt DD: Prevalence of diabetes, impaired fasting glucose and impaired glucose tolerance in U.S. adults: the Third Nation Health and Nutrition Examination Survey, 1988-1994. Diabetes Care 21:518-524, 1998
-
(1998)
Diabetes Care
, vol.21
, pp. 518-524
-
-
Harris, M.I.1
Flegal, F.M.2
Cowie, C.C.3
Eberhardt, M.S.4
Golstein, D.E.5
Little, R.R.6
Weidmeyer, H.S.7
Bryd-Holt, D.D.8
-
4
-
-
0024351558
-
Effects of aging on insulin secretion
-
Gumbiner B, Polonsky KS, Beltz WF, Wallave P, Bretchel G, Fink RI: Effects of aging on insulin secretion. Diabetes 38:1549-1556, 1989
-
(1989)
Diabetes
, vol.38
, pp. 1549-1556
-
-
Gumbiner, B.1
Polonsky, K.S.2
Beltz, W.F.3
Wallave, P.4
Bretchel, G.5
Fink, R.I.6
-
5
-
-
0021933723
-
Pathogenesis of age-related glucose intolerance in man: Insulin resistance and decreased beta cell function
-
Chen M, Bergman RN, Pacini G, Porte D: Pathogenesis of age-related glucose intolerance in man: Insulin resistance and decreased beta cell function. J Clin Endocrinol Metab 60:13-20, 1985
-
(1985)
J Clin Endocrinol Metab
, vol.60
, pp. 13-20
-
-
Chen, M.1
Bergman, R.N.2
Pacini, G.3
Porte, D.4
-
6
-
-
0025297306
-
Effect of exercise on insulin action, glucose tolerance and insulin secretion in aging
-
Kahn SE, Larson VJ, Beard JC, Cain KC, Abrass IB. Effect of exercise on insulin action, glucose tolerance and insulin secretion in aging. Am J Physiol 258:E937-E943, 1990
-
(1990)
Am J Physiol
, vol.258
-
-
Kahn, S.E.1
Larson, V.J.2
Beard, J.C.3
Cain, K.C.4
Abrass, I.B.5
-
7
-
-
0038353641
-
Mechanisms of age-associated deterioration in glucose tolerance: Contribution of alterations in insulin secretion, action, and clearance
-
Basu R, Breda E, Oberg AL, Powell CC, Dalla Man C, Basu A, Vittone JL, Klee GG, Arora P, Jensen MD, Toffolo G, Cobelli C, Rizza A: Mechanisms of age-associated deterioration in glucose tolerance: contribution of alterations in insulin secretion, action, and clearance. Diabetes 52:1738-1748, 2003
-
(2003)
Diabetes
, vol.52
, pp. 1738-1748
-
-
Basu, R.1
Breda, E.2
Oberg, A.L.3
Powell, C.C.4
Dalla Man, C.5
Basu, A.6
Vittone, J.L.7
Klee, G.G.8
Arora, P.9
Jensen, M.D.10
Toffolo, G.11
Cobelli, C.12
Rizza, A.13
-
8
-
-
0036315001
-
Relationships among age, proinsulin conversion, and β-cell function in nondiabetic humans
-
Fritsche A, Madaus A, Stefan N, Tschritter O, Maerker E, Teigeler A, Haring H, Stumvoll M: Relationships among age, proinsulin conversion, and β-cell function in nondiabetic humans. Diabetes 51 (Suppl. 1):S234-S239, 2002
-
(2002)
Diabetes
, vol.51
, Issue.SUPPL. 1
-
-
Fritsche, A.1
Madaus, A.2
Stefan, N.3
Tschritter, O.4
Maerker, E.5
Teigeler, A.6
Haring, H.7
Stumvoll, M.8
-
9
-
-
0027288897
-
Relationship between glucose tolerance and glucose-stimulated insulin response in 65-year olds
-
Bourey RE, Kohrt WM, Kirwan JP, Staten MA< King DS, Holloszy JO: Relationship between glucose tolerance and glucose-stimulated insulin response in 65-year olds. J Gerontol 48:M122-M127, 1993
-
(1993)
J Gerontol
, vol.48
-
-
Bourey, R.E.1
Kohrt, W.M.2
Kirwan, J.P.3
Staten, M.A.4
King, D.S.5
Holloszy, J.O.6
-
10
-
-
0027199747
-
The effect of age on insulin response and glucose utilization during four hyperglycemic plateaus
-
Elahi D, Muller DC, McAloon-Dyke M, Tobin JD, Andres R: The effect of age on insulin response and glucose utilization during four hyperglycemic plateaus. Exp Gerontol 28:393-409, 1993
-
(1993)
Exp Gerontol
, vol.28
, pp. 393-409
-
-
Elahi, D.1
Muller, D.C.2
McAloon-Dyke, M.3
Tobin, J.D.4
Andres, R.5
-
11
-
-
0000567961
-
Caloric restriction reverses hepatic insulin resistance in aging rats by decreasing visceral fat
-
Barzilai N, Banerjee S, Hawkins M, Chen W, Rossetti L. Caloric restriction reverses hepatic insulin resistance in aging rats by decreasing visceral fat. J Clin Invest 101:1353-1361, 1998
-
(1998)
J Clin Invest
, vol.101
, pp. 1353-1361
-
-
Barzilai, N.1
Banerjee, S.2
Hawkins, M.3
Chen, W.4
Rossetti, L.5
-
12
-
-
0033947158
-
Ability of insulin to modulate hepatic glucose production in aging rats is impaired by fat accumulation
-
Gupta G, Cases JA, She L, Ma XH, Yang XM, Hu M, Wu J, Rossetti L, Barzilai N: Ability of insulin to modulate hepatic glucose production in aging rats is impaired by fat accumulation. Am J Physiol Endocrinol Metab 278:E985-E991, 2000
-
(2000)
Am J Physiol Endocrinol Metab
, vol.278
-
-
Gupta, G.1
Cases, J.A.2
She, L.3
Ma, X.H.4
Yang, X.M.5
Hu, M.6
Wu, J.7
Rossetti, L.8
Barzilai, N.9
-
13
-
-
0036787345
-
Removal of visceral fat prevents insulin resistance and glucose intolerance of aging: An adipokine-mediated process?
-
Gabriely I, Ma XH, Yang XM, Atzmon G, Raja MW, Berg AH, Scherer P, Rossetti L, Barzilai N: Removal of visceral fat prevents insulin resistance and glucose intolerance of aging: an adipokine-mediated process? Diabetes 51:2951-2958, 2002
-
(2002)
Diabetes
, vol.51
, pp. 2951-2958
-
-
Gabriely, I.1
Ma, X.H.2
Yang, X.M.3
Atzmon, G.4
Raja, M.W.5
Berg, A.H.6
Scherer, P.7
Rossetti, L.8
Barzilai, N.9
-
14
-
-
0032938719
-
Surgical removal of visceral fat reverses hepatic insulin resistance
-
Barzilai N, She L, Liu BQ, Vuguin P, Cohen P, Wang J, Rossetti L: Surgical removal of visceral fat reverses hepatic insulin resistance. Diabetes 48:94-98, 1999
-
(1999)
Diabetes
, vol.48
, pp. 94-98
-
-
Barzilai, N.1
She, L.2
Liu, B.Q.3
Vuguin, P.4
Cohen, P.5
Wang, J.6
Rossetti, L.7
-
15
-
-
0032553418
-
ICV leptin regulates hepatic but not peripheral glucose fluxes
-
Lisen Liu, George Karkanias, Jose Mores, Meredith Hawkins, Nir Barzilai, Jiali Wang, Lucianno Rossetti: ICV leptin regulates hepatic but not peripheral glucose fluxes. J Biol Chem 273:31160-31167, 1998
-
(1998)
J Biol Chem
, vol.273
, pp. 31160-31167
-
-
Liu, L.1
Karkanias, G.2
Mores, J.3
Hawkins, M.4
Barzilai, N.5
Wang, J.6
Rossetti, L.7
-
16
-
-
0031439778
-
Leptin selectively decreases visceral adiposity and enhances insulin action
-
Barzilai N, Wang J, Massilon D, Vuguin P, Hawkins M, Rossetti L: Leptin selectively decreases visceral adiposity and enhances insulin action. J Clin Invest 100:3105-3110, 1997
-
(1997)
J Clin Invest
, vol.100
, pp. 3105-3110
-
-
Barzilai, N.1
Wang, J.2
Massilon, D.3
Vuguin, P.4
Hawkins, M.5
Rossetti, L.6
-
17
-
-
0038042206
-
Physiologic effect of leptin on insulin secretion is mediated mainly through central mechanisms
-
Muzumdar R, Ma X, Yang X, Atzmon G, Bernstein J, Karkanias G, Barzilai N: Physiologic effect of leptin on insulin secretion is mediated mainly through central mechanisms. FASEB J 17:1130-1132, 2003
-
(2003)
FASEB J
, vol.17
, pp. 1130-1132
-
-
Muzumdar, R.1
Ma, X.2
Yang, X.3
Atzmon, G.4
Bernstein, J.5
Karkanias, G.6
Barzilai, N.7
-
18
-
-
0036078849
-
Comparison of insulin sensitivity, clearance and secretion estimates using euglycemic and hyperglycemic clamps in children
-
Uwaifo GI, Parikh SJ, Keil M, Elberg J, Chin J, Yanovski JA: Comparison of insulin sensitivity, clearance and secretion estimates using euglycemic and hyperglycemic clamps in children. J Clin Endocrinol Metab 87:2899-2905, 2002
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 2899-2905
-
-
Uwaifo, G.I.1
Parikh, S.J.2
Keil, M.3
Elberg, J.4
Chin, J.5
Yanovski, J.A.6
-
19
-
-
84995202142
-
Changes in anthropometric indices of body composition with age in a healthy elderly population
-
Chumlea WC, Rhyne RL, Garry PG, Hunt WC: Changes in anthropometric indices of body composition with age in a healthy elderly population. Am J Human Biol 1:457-462, 1989
-
(1989)
Am J Human Biol
, vol.1
, pp. 457-462
-
-
Chumlea, W.C.1
Rhyne, R.L.2
Garry, P.G.3
Hunt, W.C.4
-
20
-
-
0020546499
-
Characterization of the insulin resistance in aging
-
Rowe JW, Minaker KL, Plotta JA, Flier JS: Characterization of the insulin resistance in aging. J Clin Invest 71:1523-1535, 1983
-
(1983)
J Clin Invest
, vol.71
, pp. 1523-1535
-
-
Rowe, J.W.1
Minaker, K.L.2
Plotta, J.A.3
Flier, J.S.4
-
21
-
-
0018702014
-
Glucose intolerance and aging: Evidence for tissue insensitivity to insulin
-
DeFronzo RA: Glucose intolerance and aging: evidence for tissue insensitivity to insulin. Diabetes 28:1095-1101, 1979
-
(1979)
Diabetes
, vol.28
, pp. 1095-1101
-
-
DeFronzo, R.A.1
-
22
-
-
0037382514
-
Glucose allostasis
-
Stumvoll M, Tataranni PA, Stefan N, Vozarova B, Bogardus C: Glucose allostasis. Diabetes 52:903-909, 2003
-
(2003)
Diabetes
, vol.52
, pp. 903-909
-
-
Stumvoll, M.1
Tataranni, P.A.2
Stefan, N.3
Vozarova, B.4
Bogardus, C.5
-
23
-
-
0027375768
-
Quantification of the relationship between insulin sensitivity and β-cell function in human subjects. Evidence for a hyperbolic function
-
Kahn SE, Prigeon RL, McCulloch DK, Boyko EJ, Bergman RN, Schwartz MW, Neifing JL, Ward WK, Beard JC, Palmer JP, Porte D Jr. Quantification of the relationship between insulin sensitivity and β-cell function in human subjects. Evidence for a hyperbolic function. Diabetes 42:1663-1672, 1993
-
(1993)
Diabetes
, vol.42
, pp. 1663-1672
-
-
Kahn, S.E.1
Prigeon, R.L.2
McCulloch, D.K.3
Boyko, E.J.4
Bergman, R.N.5
Schwartz, M.W.6
Neifing, J.L.7
Ward, W.K.8
Beard, J.C.9
Palmer, J.P.10
Porte Jr., D.11
-
24
-
-
0032742992
-
The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus
-
Weyer C, Bogardus C, Mott DM, Pratey RE: The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus. J Clin Invest 104:787-794, 1999
-
(1999)
J Clin Invest
, vol.104
, pp. 787-794
-
-
Weyer, C.1
Bogardus, C.2
Mott, D.M.3
Pratey, R.E.4
-
25
-
-
0025174047
-
Chronic in vivo hyperglycemia impairs phosphoinositide hydrolysis and insulin release in isolated perfused rat islets
-
Zawich WS, Zawich KC, Shulman GI, Rossetti L: Chronic in vivo hyperglycemia impairs phosphoinositide hydrolysis and insulin release in isolated perfused rat islets. Endocrinology 126:253-260, 1990
-
(1990)
Endocrinology
, vol.126
, pp. 253-260
-
-
Zawich, W.S.1
Zawich, K.C.2
Shulman, G.I.3
Rossetti, L.4
-
26
-
-
0035125097
-
Physiologic increase in plasma leptin markedly inhibits insulin secretion in vivo
-
Cases JA, Gabriely I, Ma XH, Yang XM, Michaeli T, Fleischer N, Rossetti L, Barzilai N: Physiologic increase in plasma leptin markedly inhibits insulin secretion in vivo. Diabetes 50:348-352, 2001
-
(2001)
Diabetes
, vol.50
, pp. 348-352
-
-
Cases, J.A.1
Gabriely, I.2
Ma, X.H.3
Yang, X.M.4
Michaeli, T.5
Fleischer, N.6
Rossetti, L.7
Barzilai, N.8
-
27
-
-
0019903957
-
Influence of age on clearance of insulin in man
-
Minaker KJ, Rowe JW, Tonino R, Plotta JA: Influence of age on clearance of insulin in man. Diabetes 31:851-855, 1982
-
(1982)
Diabetes
, vol.31
, pp. 851-855
-
-
Minaker, K.J.1
Rowe, J.W.2
Tonino, R.3
Plotta, J.A.4
-
28
-
-
0021962194
-
The metabolic clearance of insulin and the feedback inhibition of insulin secretion are altered with aging
-
Fink RI, Revers RR, Kolterman OG, Olefsky JM: The metabolic clearance of insulin and the feedback inhibition of insulin secretion are altered with aging. Diabetes 34:275-280, 1985
-
(1985)
Diabetes
, vol.34
, pp. 275-280
-
-
Fink, R.I.1
Revers, R.R.2
Kolterman, O.G.3
Olefsky, J.M.4
-
29
-
-
0020659023
-
Effect of age and diet on insulin secretion and insulin action in the rat
-
Reaven E, Wright D, Solomon R, Ho H, Reaven GM: Effect of age and diet on insulin secretion and insulin action in the rat. Diabetes 32:175-180, 1983
-
(1983)
Diabetes
, vol.32
, pp. 175-180
-
-
Reaven, E.1
Wright, D.2
Solomon, R.3
Ho, H.4
Reaven, G.M.5
-
30
-
-
0024451894
-
Secretion of insulin during aging
-
Adelman RC: Secretion of insulin during aging. J Am Geriatr Soc 37:983-990, 1989
-
(1989)
J Am Geriatr Soc
, vol.37
, pp. 983-990
-
-
Adelman, R.C.1
-
31
-
-
0023579701
-
Effect of age and sex on rat endocrine pancreas
-
Reaven EP, Curry DL, Reaven GM: Effect of age and sex on rat endocrine pancreas. Diabetes 36:1397-1400, 1987
-
(1987)
Diabetes
, vol.36
, pp. 1397-1400
-
-
Reaven, E.P.1
Curry, D.L.2
Reaven, G.M.3
-
32
-
-
0019488092
-
Structure and function changes in the endocrine pancreas of aging rats with reference to the modulating effects of exercise and caloric restriction
-
Reaven EP, Reaven GM: Structure and function changes in the endocrine pancreas of aging rats with reference to the modulating effects of exercise and caloric restriction. J Clin Invest 68:75-84, 1981
-
(1981)
J Clin Invest
, vol.68
, pp. 75-84
-
-
Reaven, E.P.1
Reaven, G.M.2
-
33
-
-
0018757755
-
Effect of age on glucose stimulated insulin release by the beta cell of the rat
-
Reaven EP, Gold G, Reaven GM. Effect of age on glucose stimulated insulin release by the beta cell of the rat. J Clin Invest 64:591-599, 1979
-
(1979)
J Clin Invest
, vol.64
, pp. 591-599
-
-
Reaven, E.P.1
Gold, G.2
Reaven, G.M.3
-
34
-
-
0020696947
-
Effects of age and environment factors on insulin release from perifused pancreas of the rats
-
Reaven C, Curry D, Moore J, Reaven G: Effects of age and environment factors on insulin release from perifused pancreas of the rats. J Clin Invest 71:345-350, 1983
-
(1983)
J Clin Invest
, vol.71
, pp. 345-350
-
-
Reaven, C.1
Curry, D.2
Moore, J.3
Reaven, G.4
-
35
-
-
0031037487
-
B cells of aging rats: Impaired stimulus-secretion coupling but normal susceptibility to adverse effects of a diabetic state
-
Inoue K, Norgren S, Luthman H, Moller C, Grill V: B cells of aging rats: impaired stimulus-secretion coupling but normal susceptibility to adverse effects of a diabetic state. Metabolism 46:242-246, 1997
-
(1997)
Metabolism
, vol.46
, pp. 242-246
-
-
Inoue, K.1
Norgren, S.2
Luthman, H.3
Moller, C.4
Grill, V.5
-
36
-
-
0031982337
-
NEFA elevation during a hyperglycemic clamp enhances insulin secretion
-
Chalkley SM, Kraegen EW, Furler SM, Campbell LV, Chisholm DJ: NEFA elevation during a hyperglycemic clamp enhances insulin secretion. Diabet Med 15:327-333, 1998
-
(1998)
Diabet Med
, vol.15
, pp. 327-333
-
-
Chalkley, S.M.1
Kraegen, E.W.2
Furler, S.M.3
Campbell, L.V.4
Chisholm, D.J.5
-
37
-
-
0036434385
-
Interaction between specific fatty acids, GLP-1 and insulin secretion in humans
-
Beysen C, Karpe F, Fielding BA, Clark A, Levy C, Frayn KN: Interaction between specific fatty acids, GLP-1 and insulin secretion in humans. Diabetologia 45:1533-1541, 2002
-
(2002)
Diabetologia
, vol.45
, pp. 1533-1541
-
-
Beysen, C.1
Karpe, F.2
Fielding, B.A.3
Clark, A.4
Levy, C.5
Frayn, K.N.6
-
38
-
-
0037211642
-
Pleiotropic effects of fatty acids on pancreatic B cells
-
Haber EP, Ximenes HMA, Procopio J, Carvho CRO, Curi R, Carpinelli AR: Pleiotropic effects of fatty acids on pancreatic B cells. J Cell Physiol 194:1-12, 2002
-
(2002)
J Cell Physiol
, vol.194
, pp. 1-12
-
-
Haber, E.P.1
Ximenes, H.M.A.2
Procopio, J.3
Carvho, C.R.O.4
Curi, R.5
Carpinelli, A.R.6
-
39
-
-
0030748260
-
Signal transduction mechanisms in nutrient-induced insulin secretion
-
Prentki M, Tornheim K, Corkey B: Signal transduction mechanisms in nutrient-induced insulin secretion. Diabetologia 40:S32-S41, 1997
-
(1997)
Diabetologia
, vol.40
-
-
Prentki, M.1
Tornheim, K.2
Corkey, B.3
-
40
-
-
0034737731
-
Acute stimulation with long chain acyl-coA enhances exocytosis in insulin-secreting cells (HIT T-15 and NMRI beta-cells)
-
Deeney JT, Gromada J, Hoy M, Olsen HL, Rhodes CJ, Prentki M, Bergren PO, Corkey BE: Acute stimulation with long chain acyl-coA enhances exocytosis in insulin-secreting cells (HIT T-15 and NMRI beta-cells). J Biol Chem 275:9363-9368, 2000
-
(2000)
J Biol Chem
, vol.275
, pp. 9363-9368
-
-
Deeney, J.T.1
Gromada, J.2
Hoy, M.3
Olsen, H.L.4
Rhodes, C.J.5
Prentki, M.6
Bergren, P.O.7
Corkey, B.E.8
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