Regulation of Drosophila life span by olfaction and food-derived odors

Science

Volumn 315, Issue 5815, 2007, Pages 1133-1137

  Libert, Sergiy ^a   Zwiener, Jessica ^a   Chu, Xiaowen ^a   VanVoorhies, Wayne ^b   Roman, Gregg ^c   Pletcher, Scott D ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b NEW MEXICO STATE UNIVERSITY   (United States)

^c UNIVERSITY OF HOUSTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGING; FLY; FOOD; ODOR; OLFACTION; PHYSIOLOGY;

AGING; ARTICLE; CAENORHABDITIS ELEGANS; DIET RESTRICTION; DROSOPHILA; FEEDING BEHAVIOR; FOOD; GENE EXPRESSION REGULATION; GENE MUTATION; LIFESPAN; NEMATODE; NONHUMAN; NUTRIENT; ODOR; OLFACTORY SYSTEM; OR83B TRANSGENE; PRIORITY JOURNAL; SMELLING; TRANSGENE;

AGING; ANIMALS; CROSSES, GENETIC; DIET; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FEMALE; FOOD; LONGEVITY; MALE; MODELS, ANIMAL; MUTATION; ODORS; PHENOTYPE; RECEPTORS, ODORANT; REPRODUCTION; SMELL; TRANSGENES; YEASTS;

DROSOPHILA MELANOGASTER;

EID: 33847259770     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1136610     Document Type: Article

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23. We thank S. Lou, D. Skorupa, M. Tierney, and the Pletcher laboratory for help with Drosophila husbandry and metabolic assays; and J. Ferri's for his technical assistance in the behavioral assays. C. Gendron, M. Tatar, three anonymous reviewers, and members of the Antebi laboratory provided comments on the manuscript. The research is supported by NIH (R01AG023166), Glenn Foundation, the Ellison Medical Foundation to S.D.P., and the American Federation for Aging Research to S.L. and S.D.P.