Systematic gene expression profile of hypothalamus in calorie-restricted mice implicates the involvement of mTOR signaling in neuroprotective activity

Mechanisms of Ageing and Development

Volumn 130, Issue 9, 2009, Pages 602-610

  Wu, Pu ^a   Jiang, Cecilia ^a   Shen, Qian ^a   Hu, Yinghe ^a  

^a B326 Science Building   (China)

Author keywords

Aging; Calorie restriction; Hypothalamus; Mice; Microarray; mTOR

Indexed keywords

ACTIN; ALDEHYDE DEHYDROGENASE ISOENZYME 2; BETA TUBULIN; BIM PROTEIN; COMPLEMENT COMPONENT C1Q; EPHRIN RECEPTOR A7; HEAT SHOCK PROTEIN 70; HEAT SHOCK TRANSCRIPTION FACTOR 1; INITIATION FACTOR 2; INTERLEUKIN 6 RECEPTOR ALPHA; INTERLEUKIN 7 RECEPTOR; JANUS KINASE 1; LYMPHOID ENHANCER FACTOR 1; MAMMALIAN TARGET OF RAPAMYCIN; NEURONAL APOPTOSIS INHIBITORY PROTEIN; NEUROPEPTIDE Y RECEPTOR; NOTCH RECEPTOR; PARAQUAT; PROOPIOMELANOCORTIN; PROTEIN BCL 2; S6 KINASE; SECRETED FRIZZLED RELATED PROTEIN 4; SOMATOMEDIN C RECEPTOR; STEM CELL FACTOR RECEPTOR; SUPPRESSOR OF CYTOKINE SIGNALING 1; TRANSCRIPTION FACTOR FOXO; WNT PROTEIN;

AGE; AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BRAIN DEVELOPMENT; CALORIC INTAKE; CALORIC RESTRICTION; CONTROLLED STUDY; DOWN REGULATION; FOOD INTAKE; GENE EXPRESSION PROFILING; GENE FUNCTION; HYPOTHALAMUS; INFLAMMATION; INHIBITION KINETICS; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NEUROPROTECTION; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STRESS; UNINDEXED SEQUENCE; UPREGULATION; WEANING;

ANIMALS; CALORIC RESTRICTION; GENE EXPRESSION PROFILING; HYPOTHALAMUS; MICE; NEUROPROTECTIVE AGENTS; SIGNAL TRANSDUCTION; SIROLIMUS; TIME FACTORS;

MAMMALIA; MUS;

EID: 70049103975     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mad.2009.07.005     Document Type: Article

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