메뉴 건너뛰기




Volumn 42, Issue 12, 2013, Pages 5552-5576

Cytokines as biomarkers of nanoparticle immunotoxicity

Author keywords

[No Author keywords available]

Indexed keywords


EID: 84877267968     PISSN: 03060012     EISSN: 14604744     Source Type: Journal    
DOI: 10.1039/c3cs60064e     Document Type: Article
Times cited : (346)

References (204)
  • 1
    • 80054748030 scopus 로고    scopus 로고
    • The importance of chemistry in creating well-defined nanoscopic embedded therapeutics: Devices capable of the dual functions of imaging and therapy
    • A. M. Nystrom, K. L. Wooley, The importance of chemistry in creating well-defined nanoscopic embedded therapeutics: devices capable of the dual functions of imaging and therapy, Acc. Chem. Res. 2011, 44, 969-978
    • (2011) Acc. Chem. Res. , vol.44 , pp. 969-978
    • Nystrom, A.M.1    Wooley, K.L.2
  • 4
    • 84858673601 scopus 로고    scopus 로고
    • Design of polymeric nanoparticles for biomedical delivery applications
    • M. Elsabahy, K. L. Wooley, Design of polymeric nanoparticles for biomedical delivery applications, Chem. Soc. Rev. 2012, 41, 2545-2561
    • (2012) Chem. Soc. Rev. , vol.41 , pp. 2545-2561
    • Elsabahy, M.1    Wooley, K.L.2
  • 6
    • 73249147280 scopus 로고    scopus 로고
    • Structure-activity relationships of cationic shell-crosslinked knedel-like nanoparticles: Shell composition and transfection efficiency/cytotoxicity
    • K. Zhang, H. Fang, Z. Wang, Z. Li, J. S. Taylor, K. L. Wooley, Structure-activity relationships of cationic shell-crosslinked knedel-like nanoparticles: shell composition and transfection efficiency/cytotoxicity, Biomaterials, 2010, 31, 1805-1813
    • (2010) Biomaterials , vol.31 , pp. 1805-1813
    • Zhang, K.1    Fang, H.2    Wang, Z.3    Li, Z.4    Taylor, J.S.5    Wooley, K.L.6
  • 7
    • 69249211285 scopus 로고    scopus 로고
    • Well-defined cationic shell crosslinked nanoparticles for efficient delivery of DNA or peptide nucleic acids
    • K. Zhang, H. Fang, G. Shen, J. S. Taylor, K. L. Wooley, Well-defined cationic shell crosslinked nanoparticles for efficient delivery of DNA or peptide nucleic acids, Proc. Am. Thorac. Soc. 2009, 6, 450-457
    • (2009) Proc. Am. Thorac. Soc. , vol.6 , pp. 450-457
    • Zhang, K.1    Fang, H.2    Shen, G.3    Taylor, J.S.4    Wooley, K.L.5
  • 9
    • 84866158839 scopus 로고    scopus 로고
    • V. Torchilin and M. Amiji, Pan Stanford Publishing, Hackensack
    • M. Elsabahy, M. H. Dufresne and J. C. Leroux, in Materials for Nanomedicine, ed. V. Torchilin and M. Amiji, Pan Stanford Publishing, Hackensack, 2010, pp. 169–234
    • (2010) Materials for Nanomedicine , pp. 169-234
    • Elsabahy, M.1    Dufresne, M.H.2    Leroux, J.C.3
  • 10
    • 34547690726 scopus 로고    scopus 로고
    • Immunological properties of engineered nanomaterials, Nat
    • M. A. Dobrovolskaia, S. E. McNeil, Immunological properties of engineered nanomaterials, Nat. Nanotechnol. 2007, 2, 469-478
    • (2007) Nanotechnol. , vol.2 , pp. 469-478
    • Dobrovolskaia, M.A.1    Mc Neil, S.E.2
  • 12
    • 84857121722 scopus 로고    scopus 로고
    • Interactions of nanomaterials with the immune system, Wiley Interdiscip
    • S. Hussain, J. A. Vanoirbeek, P. H. Hoet, Interactions of nanomaterials with the immune system, Wiley Interdiscip. Rev.: Nanomed. Nanobiotechnol. 2011, 4, 169-183
    • (2011) Rev.: Nanomed. Nanobiotechnol , vol.4 , pp. 169-183
    • Hussain, S.1    Vanoirbeek, J.A.2    Hoet, P.H.3
  • 15
    • 77649180804 scopus 로고    scopus 로고
    • The immune effects of naturally occurring and synthetic nanoparticles
    • C. Chang, The immune effects of naturally occurring and synthetic nanoparticles, J. Autoimmun. 2010, 34, J234-J246
    • (2010) J. Autoimmun. , vol.34 , pp. J234-J246
    • Chang, C.1
  • 16
    • 34248531422 scopus 로고    scopus 로고
    • Cytokine-release syndrome: Overview and nursing implications
    • S. Breslin, Cytokine-release syndrome: overview and nursing implications, Clin. J. Oncol. Nurs. 2007, 11, 37-42
    • (2007) Clin. J. Oncol. Nurs. , vol.11 , pp. 37-42
    • Breslin, S.1
  • 18
    • 0033588526 scopus 로고    scopus 로고
    • Novel aggregate structure adjuvants modulate lymphocyte proliferation and Th1 and Th2 cytokine profiles in ovalbumin immunized mice
    • P. Rajananthanan, G. S. Attard, N. A. Sheikh, W. J. Morrow, Novel aggregate structure adjuvants modulate lymphocyte proliferation and Th1 and Th2 cytokine profiles in ovalbumin immunized mice, Vaccine, 1999, 18, 140-152
    • (1999) Vaccine , vol.18 , pp. 140-152
    • Rajananthanan, P.1    Attard, G.S.2    Sheikh, N.A.3    Morrow, W.J.4
  • 19
    • 4444287698 scopus 로고    scopus 로고
    • Delayed type hypersensitivity: Current theories with an historic perspective, Dermatol
    • C. A. Black, Delayed type hypersensitivity: current theories with an historic perspective, Dermatol. Online J. 1999, 5, 7
    • (1999) Online J. , vol.5 , pp. 7
    • Black, C.A.1
  • 20
    • 77955654148 scopus 로고    scopus 로고
    • Human Th9 cells: Inflammatory cytokines modulate IL-9 production through the induction of IL-21
    • C. S. Ma, S. G. Tangye, E. K. Deenick, Human Th9 cells: inflammatory cytokines modulate IL-9 production through the induction of IL-21, Immunol. Cell Biol. 2010, 88, 621-623
    • (2010) Immunol. Cell Biol. , vol.88 , pp. 621-623
    • Ma, C.S.1    Tangye, S.G.2    Deenick, E.K.3
  • 22
    • 23944493698 scopus 로고
    • Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins
    • T. R. Mosmann, H. Cherwinski, M. W. Bond, M. A. Giedlin, R. L. Coffman, Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins, 1986, J. Immunol. 2005, 175, 5-14
    • (1986) J. Immunol. , vol.2005 , Issue.175 , pp. 5-14
    • Mosmann, T.R.1    Cherwinski, H.2    Bond, M.W.3    Giedlin, M.A.4    Coffman, R.L.5
  • 25
    • 79959355853 scopus 로고    scopus 로고
    • Immune modulation for treatment of allergic disease
    • T. H. Nguyen, T. B. Casale, Immune modulation for treatment of allergic disease, Immunol. Rev. 2011, 242, 258-271
    • (2011) Immunol. Rev. , vol.242 , pp. 258-271
    • Nguyen, T.H.1    Casale, T.B.2
  • 26
    • 0041917266 scopus 로고    scopus 로고
    • Th1/Th2 balance: The hypothesis, its limitations and implications for health and disease
    • P. Kidd, Th1/Th2 balance: the hypothesis, its limitations and implications for health and disease, Altern. Med. Rev. 2003, 8, 223-246
    • (2003) Altern. Med. Rev. , vol.8 , pp. 223-246
    • Kidd, P.1
  • 28
    • 0036284984 scopus 로고    scopus 로고
    • The role of Th1/Th2 polarization in mucosal immunity
    • M. F. Neurath, S. Finotto, L. H. Glimcher, The role of Th1/Th2 polarization in mucosal immunity, Nat. Med. 2002, 8, 567-573
    • (2002) Nat. Med. , vol.8 , pp. 567-573
    • Neurath, M.F.1    Finotto, S.2    Glimcher, L.H.3
  • 29
    • 0003635705 scopus 로고    scopus 로고
    • D. H. Margulies, John Wiley and Sons, Inc. New York
    • E. Benjamini, R. Coico and G. Sunshine, in Immunology, ed. D. H. Margulies, John Wiley and Sons, Inc. New York, 2000
    • (2000) Immunology
    • Benjamini, E.1    Coico, R.2    Sunshine, G.3
  • 30
    • 41549109750 scopus 로고    scopus 로고
    • Biological interactions of quantum dot nanoparticles in skin and in human epidermal keratinocytes
    • L. W. Zhang, W. W. Yu, V. L. Colvin, N. A. Monteiro-Riviere, Biological interactions of quantum dot nanoparticles in skin and in human epidermal keratinocytes, Toxicol. Appl. Pharmacol. 2008, 228, 200-211
    • (2008) Toxicol. Appl. Pharmacol. , vol.228 , pp. 200-211
    • Zhang, L.W.1    Yu, W.W.2    Colvin, V.L.3    Monteiro-Riviere, N.A.4
  • 31
    • 33845750500 scopus 로고    scopus 로고
    • Riviere, Surface coatings determine cytotoxicity and irritation potential of quantum dot nanoparticles in epidermal keratinocytes
    • J. P. Ryman-Rasmussen, J. E. Riviere, N. A. Monteiro-Riviere, Surface coatings determine cytotoxicity and irritation potential of quantum dot nanoparticles in epidermal keratinocytes, J. Invest. Dermatol. 2007, 127, 143-153
    • (2007) J. Invest. Dermatol. , vol.127 , pp. 143-153
    • Ryman-Rasmussen, J.P.1    Riviere, J.E.2    Monteiro, N.A.3
  • 32
    • 0242486382 scopus 로고    scopus 로고
    • The mechanism of retinol-induced irritation and its application to anti-irritant development
    • B. H. Kim, Y. S. Lee, K. S. Kang, The mechanism of retinol-induced irritation and its application to anti-irritant development, Toxicol. Lett. 2003, 146, 65-73
    • (2003) Toxicol. Lett. , vol.146 , pp. 65-73
    • Kim, B.H.1    Lee, Y.S.2    Kang, K.S.3
  • 33
    • 0037031754 scopus 로고    scopus 로고
    • Keratinocytes and cytokines, Vet
    • A. Grone, Keratinocytes and cytokines, Vet. Immunol. Immunopathol. 2002, 88, 1-12
    • (2002) Immunol. Immunopathol. , vol.88 , pp. 1-12
    • Grone, A.1
  • 34
    • 77953303124 scopus 로고    scopus 로고
    • Toxicity pathway focused gene expression profiling of PEI-based polymers for pulmonary applications
    • A. Beyerle, M. Irmler, J. Beckers, T. Kissel, T. Stoeger, Toxicity pathway focused gene expression profiling of PEI-based polymers for pulmonary applications, Mol. Pharmaceutics, 2010, 7, 727-737
    • (2010) Mol. Pharmaceutics , vol.7 , pp. 727-737
    • Beyerle, A.1    Irmler, M.2    Beckers, J.3    Kissel, T.4    Stoeger, T.5
  • 35
    • 20444364176 scopus 로고    scopus 로고
    • Increased expression of chemokine KC, an interleukin-8 homologue, in a model of oxygen-induced retinopathy
    • M. R. Powers, M. H. Davies, J. P. Eubanks, Increased expression of chemokine KC, an interleukin-8 homologue, in a model of oxygen-induced retinopathy, Curr. Eye Res. 2005, 30, 299-307
    • (2005) Curr. Eye Res. , vol.30 , pp. 299-307
    • Powers, M.R.1    Davies, M.H.2    Eubanks, J.P.3
  • 37
    • 84878624361 scopus 로고
    • D. P. Stites and A. I. Terr, Appleton and Lange, Norwalk, CA
    • L. Lanier, in Basic human immunology, ed. D. P. Stites and A. I. Terr, Appleton and Lange, Norwalk, CA, 1991
    • (1991) Basic Human Immunology
    • Lanier, L.1
  • 38
    • 84864511390 scopus 로고    scopus 로고
    • PH-sensitive vesicles, polymeric micelles and nanospheres prepared with polycarboxylates
    • A. E. Felber, M. H. Dufresne, J. C. Leroux, pH-sensitive vesicles, polymeric micelles and nanospheres prepared with polycarboxylates, Adv. Drug Delivery Rev. 2010, 64, 979-992
    • (2010) Adv. Drug Delivery Rev. , vol.64 , pp. 979-992
    • Felber, A.E.1    Dufresne, M.H.2    Leroux, J.C.3
  • 40
    • 77955175216 scopus 로고    scopus 로고
    • Strategies in the design of nanoparticles for therapeutic applications
    • R. A. Petros, J. M. DeSimone, Strategies in the design of nanoparticles for therapeutic applications, Nat. Rev. Drug Discovery, 2010, 9, 615-627
    • (2010) Nat. Rev. Drug Discovery , vol.9 , pp. 615-627
    • Petros, R.A.1    Desimone, J.M.2
  • 41
    • 80054741757 scopus 로고    scopus 로고
    • Self-assembled targeted nanoparticles: Evolution of technologies and bench to bedside translation
    • J. Shi, Z. Xiao, N. Kamaly, O. C. Farokhzad, Self-assembled targeted nanoparticles: evolution of technologies and bench to bedside translation, Acc. Chem. Res. 2011, 44, 1123-1134
    • (2011) Acc. Chem. Res. , vol.44 , pp. 1123-1134
    • Shi, J.1    Xiao, Z.2    Kamaly, N.3    Farokhzad, O.C.4
  • 42
    • 78649974950 scopus 로고    scopus 로고
    • Advances in the field of nanooncology
    • K. K. Jain, Advances in the field of nanooncology, BMC Med. 2010, 8, 83
    • (2010) BMC Med. , vol.8 , pp. 83
    • Jain, K.K.1
  • 44
    • 0033199598 scopus 로고    scopus 로고
    • The inhibitory role of CpG immunostimulatory motifs in cationic lipid vector-mediated transgene expression in vivo
    • Y. Tan, S. Li, B. R. Pitt, L. Huang, The inhibitory role of CpG immunostimulatory motifs in cationic lipid vector-mediated transgene expression in vivo, Hum. Gene Ther. 1999, 10, 2153-2161
    • (1999) Hum. Gene Ther. , vol.10 , pp. 2153-2161
    • Tan, Y.1    Li, S.2    Pitt, B.R.3    Huang, L.4
  • 45
    • 28444450450 scopus 로고    scopus 로고
    • Paclitaxel poliglumex (XYOTAX, CT-2103): A macromolecular taxane
    • J. W. Singer, Paclitaxel poliglumex (XYOTAX, CT-2103): a macromolecular taxane, J. Controlled Release, 2005, 109, 120-126
    • (2005) J. Controlled Release , vol.109 , pp. 120-126
    • Singer, J.W.1
  • 49
    • 0035937592 scopus 로고    scopus 로고
    • Block copolymer micelles for drug delivery: Design, characterization and biological significance
    • K. Kataoka, A. Harada, Y. Nagasaki, Block copolymer micelles for drug delivery: design, characterization and biological significance, Adv. Drug Delivery Rev. 2001, 47, 113-131
    • (2001) Adv. Drug Delivery Rev. , vol.47 , pp. 113-131
    • Kataoka, K.1    Harada, A.2    Nagasaki, Y.3
  • 50
    • 33845388144 scopus 로고    scopus 로고
    • Micellar nanocarriers: Pharmaceutical perspectives
    • V. P. Torchilin, Micellar nanocarriers: pharmaceutical perspectives, Pharm. Res. 2007, 24, 1-16
    • (2007) Pharm. Res. , vol.24 , pp. 1-16
    • Torchilin, V.P.1
  • 52
    • 84859589858 scopus 로고    scopus 로고
    • Strategies toward well-defined polymer nanoparticles inspired by nature: Chemistry versus versatility
    • M. Elsabahy, K. L. Wooley, Strategies toward well-defined polymer nanoparticles inspired by nature: chemistry versus versatility, J. Polym. Sci. Part A: Polym. Chem. 2012, 50, 1869-1880
    • (2012) J. Polym. Sci. Part A: Polym. Chem. , vol.50 , pp. 1869-1880
    • Elsabahy, M.1    Wooley, K.L.2
  • 53
    • 84857710156 scopus 로고    scopus 로고
    • PEG Nanocages as non-sheddable stabilizers for drug nanocrystals
    • K. Fuhrmann, J. D. Schulz, M. A. Gauthier, J. C. Leroux, PEG Nanocages as non-sheddable stabilizers for drug nanocrystals, ACS Nano, 2012, 6, 1667-1676
    • (2012) ACS Nano , vol.6 , pp. 1667-1676
    • Fuhrmann, K.1    Schulz, J.D.2    Gauthier, M.A.3    Leroux, J.C.4
  • 54
    • 42649132499 scopus 로고    scopus 로고
    • Protein nanoparticles as drug carriers in clinical medicine
    • M. J. Hawkins, P. Soon-Shiong, N. Desai, Protein nanoparticles as drug carriers in clinical medicine, Adv. Drug Delivery Rev. 2008, 60, 876-885
    • (2008) Adv. Drug Delivery Rev. , vol.60 , pp. 876-885
    • Hawkins, M.J.1    Soon-Shiong, P.2    Desai, N.3
  • 55
    • 42749091133 scopus 로고    scopus 로고
    • Polymer-drug conjugates: Recent development in clinical oncology
    • C. Li, S. Wallace, Polymer-drug conjugates: recent development in clinical oncology, Adv. Drug Delivery Rev. 2008, 60, 886-898
    • (2008) Adv. Drug Delivery Rev. , vol.60 , pp. 886-898
    • Li, C.1    Wallace, S.2
  • 57
    • 77955247994 scopus 로고    scopus 로고
    • In vivo evaluation of pH-sensitive polymer-based immunoliposomes targeting the CD33 antigen
    • P. Simard, J. C. Leroux, In vivo evaluation of pH-sensitive polymer-based immunoliposomes targeting the CD33 antigen, Mol. Pharmaceutics, 2010, 7, 1098-1107
    • (2010) Mol. Pharmaceutics , vol.7 , pp. 1098-1107
    • Simard, P.1    Leroux, J.C.2
  • 60
    • 33750136313 scopus 로고    scopus 로고
    • Current state, achievements and future prospects of polymeric micelles as nanocarriers for drug and gene delivery
    • N. Nishiyama, K. Kataoka, Current state, achievements and future prospects of polymeric micelles as nanocarriers for drug and gene delivery, Pharmacol. Ther. 2006, 112, 630-648
    • (2006) Pharmacol. Ther. , vol.112 , pp. 630-648
    • Nishiyama, N.1    Kataoka, K.2
  • 61
    • 37549032712 scopus 로고    scopus 로고
    • Breaking the bonds: Non-viral vectors become chemically dynamic
    • J. A. Wolff, D. B. Rozema, Breaking the bonds: non-viral vectors become chemically dynamic, Mol. Ther. 2008, 16, 8-15
    • (2008) Mol. Ther , vol.16 , pp. 8-15
    • Wolff, J.A.1    Rozema, D.B.2
  • 66
    • 70349964558 scopus 로고    scopus 로고
    • All-in-one target-cell-specific magnetic nanoparticles for simultaneous molecular imaging and siRNA delivery
    • J. H. Lee, K. Lee, S. H. Moon, Y. Lee, T. G. Park, J. Cheon, All-in-one target-cell-specific magnetic nanoparticles for simultaneous molecular imaging and siRNA delivery, Angew. Chem. Int. Ed. 2009, 48, 4174-4179
    • (2009) Angew. Chem. Int. Ed. , vol.48 , pp. 4174-4179
    • Lee, J.H.1    Lee, K.2    Moon, S.H.3    Lee, Y.4    Park, T.G.5    Cheon, J.6
  • 68
    • 38949105860 scopus 로고    scopus 로고
    • Functionalized carbon nanotubes in drug design and discovery
    • M. Prato, K. Kostarelos, A. Bianco, Functionalized carbon nanotubes in drug design and discovery, Acc. Chem. Res. 2008, 41, 60-68
    • (2008) Acc. Chem. Res. , vol.41 , pp. 60-68
    • Prato, M.1    Kostarelos, K.2    Bianco, A.3
  • 69
    • 40349112868 scopus 로고    scopus 로고
    • Circulation and long-term fate of functionalized, biocompatible single-walled carbon nanotubes in mice probed by Raman spectroscopy
    • Z. Liu, C. Davis, W. Cai, L. He, X. Chen, H. Dai, Circulation and long-term fate of functionalized, biocompatible single-walled carbon nanotubes in mice probed by Raman spectroscopy, Proc. Natl. Acad. Sci. U. S. A. 2008, 105, 1410-1415
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 1410-1415
    • Liu, Z.1    Davis, C.2    Cai, W.3    He, L.4    Chen, X.5    Dai, H.6
  • 71
    • 67349260747 scopus 로고    scopus 로고
    • The effect of Gd@C82(OH)22 nanoparticles on the release of Th1/Th2 cytokines and induction of TNF-alpha mediated cellular immunity
    • Y. Liu, F. Jiao, Y. Qiu, W. Li, F. Lao, G. Zhou, B. Sun, G. Xing, J. Dong, Y. Zhao, Z. Chai, C. Chen, The effect of Gd@C82(OH)22 nanoparticles on the release of Th1/Th2 cytokines and induction of TNF-alpha mediated cellular immunity, Biomaterials, 2009, 30, 3934-3945
    • (2009) Biomaterials , vol.30 , pp. 3934-3945
    • Liu, Y.1    Jiao, F.2    Qiu, Y.3    Li, W.4    Lao, F.5    Zhou, G.6    Sun, B.7    Xing, G.8    Dong, J.9    Zhao, Y.10    Chai, Z.11    Chen, C.12
  • 73
    • 70349547212 scopus 로고    scopus 로고
    • Self, Exposure to titanium dioxide nanomaterials provokes inflammation of an in vitro human immune construct
    • B. C. Schanen, A. S. Karakoti, S. Seal, D. R. Drake, W. L. Warren, W. T. Self, Exposure to titanium dioxide nanomaterials provokes inflammation of an in vitro human immune construct, ACS Nano, 2009, 3, 2523-2532
    • (2009) ACS Nano , vol.3 , pp. 2523-2532
    • Schanen, B.C.1    Karakoti, A.S.2    Seal, S.3    Drake, D.R.4    Warren, W.L.W.T.5
  • 74
    • 78650231489 scopus 로고    scopus 로고
    • Nanodiamond and nanoplatinum liquid, DPV576, activates human monocyte-derived dendritic cells in vitro
    • M. Ghoneum, A. Ghoneum, J. Gimzewski, Nanodiamond and nanoplatinum liquid, DPV576, activates human monocyte-derived dendritic cells in vitro, Anticancer Res. 2010, 30, 4075-4079
    • (2010) Anticancer Res. , vol.30 , pp. 4075-4079
    • Ghoneum, M.1    Ghoneum, A.2    Gimzewski, J.3
  • 75
    • 84878098268 scopus 로고    scopus 로고
    • NLRP3 Inflammasome Activation Induced by Engineered Nanomaterials
    • B. Sun, X. Wang, Z. Ji, R. Li, T. Xia, NLRP3 Inflammasome Activation Induced by Engineered Nanomaterials, Small, 2012, DOI: 10.1002/smll.201201962
    • (2012) Small
    • Sun, B.1    Wang, X.2    Ji, Z.3    Li, R.4    Xia, T.5
  • 76
    • 84863990988 scopus 로고    scopus 로고
    • Inflammasome formation and IL-1beta release by human blood monocytes in response to silver nanoparticles
    • E. J. Yang, S. Kim, J. S. Kim, I. H. Choi, Inflammasome formation and IL-1beta release by human blood monocytes in response to silver nanoparticles, Biomaterials, 2012, 33, 6858-6867
    • (2012) Biomaterials , vol.33 , pp. 6858-6867
    • Yang, E.J.1    Kim, S.2    Kim, J.S.3    Choi, I.H.4
  • 79
    • 0035961506 scopus 로고    scopus 로고
    • Protection against Bordetella pertussis infection following parenteral or oral immunization with antigens entrapped in biodegradable particles: Effect of formulation and route of immunization on induction of Th1 and Th2 cells
    • M. A. Conway, L. Madrigal-Estebas, S. McClean, D. J. Brayden, K. H. Mills, Protection against Bordetella pertussis infection following parenteral or oral immunization with antigens entrapped in biodegradable particles: effect of formulation and route of immunization on induction of Th1 and Th2 cells, Vaccine, 2001, 19, 1940-1950
    • (2001) Vaccine , vol.19 , pp. 1940-1950
    • Conway, M.A.1    Madrigal-Estebas, L.2    Mc Clean, S.3    Brayden, D.J.4    Mills, K.H.5
  • 80
    • 51049108389 scopus 로고    scopus 로고
    • Preclinical studies to understand nanoparticle interaction with the immune system and its potential effects on nanoparticle biodistribution, Mol
    • M. A. Dobrovolskaia, P. Aggarwal, J. B. Hall, S. E. McNeil, Preclinical studies to understand nanoparticle interaction with the immune system and its potential effects on nanoparticle biodistribution, Mol. Pharmaceutics, 2008, 5, 487-495
    • (2008) Pharmaceutics , vol.5 , pp. 487-495
    • Dobrovolskaia, M.A.1    Aggarwal, P.2    Hall, J.B.3    Mc Neil, S.E.4
  • 81
    • 65749117793 scopus 로고    scopus 로고
    • Nanoparticle interaction with plasma proteins as it relates to particle biodistribution, biocompatibility and therapeutic efficacy
    • P. Aggarwal, J. B. Hall, C. B. McLeland, M. A. Dobrovolskaia, S. E. McNeil, Nanoparticle interaction with plasma proteins as it relates to particle biodistribution, biocompatibility and therapeutic efficacy, Adv. Drug Delivery Rev. 2009, 61, 428-437
    • (2009) Adv. Drug Delivery Rev. , vol.61 , pp. 428-437
    • Aggarwal, P.1    Hall, J.B.2    Mc Leland, C.B.3    Dobrovolskaia, M.A.4    Mc Neil, S.E.5
  • 83
  • 84
    • 50549086919 scopus 로고    scopus 로고
    • Co-delivery of cancer-associated antigen and Toll-like receptor 4 ligand in PLGA nanoparticles induces potent CD8+ T cell-mediated anti-tumor immunity
    • S. Hamdy, O. Molavi, Z. Ma, A. Haddadi, A. Alshamsan, Z. Gobti, S. Elhasi, J. Samuel, A. Lavasanifar, Co-delivery of cancer-associated antigen and Toll-like receptor 4 ligand in PLGA nanoparticles induces potent CD8+ T cell-mediated anti-tumor immunity, Vaccine, 2008, 26, 5046-5057
    • (2008) Vaccine , vol.26 , pp. 5046-5057
    • Hamdy, S.1    Molavi, O.2    Ma, Z.3    Haddadi, A.4    Alshamsan, A.5    Gobti, Z.6    Elhasi, S.7    Samuel, J.8    Lavasanifar, A.9
  • 85
    • 31544467293 scopus 로고    scopus 로고
    • Diphtheria toxoid loaded poly-(Epsilon-caprolactone) nanoparticles as mucosal vaccine delivery systems
    • J. Singh, S. Pandit, V. W. Bramwell, H. O. Alpar, Diphtheria toxoid loaded poly-(epsilon-caprolactone) nanoparticles as mucosal vaccine delivery systems, Methods, 2006, 38, 96-105
    • (2006) Methods , vol.38 , pp. 96-105
    • Singh, J.1    Pandit, S.2    Bramwell, V.W.3    Alpar, H.O.4
  • 86
    • 79953832337 scopus 로고    scopus 로고
    • Aerosolized PLA and PLGA nanoparticles enhance humoral, mucosal and cytokine responses to hepatitis B vaccine
    • C. Thomas, A. Rawat, L. Hope-Weeks, F. Ahsan, Aerosolized PLA and PLGA nanoparticles enhance humoral, mucosal and cytokine responses to hepatitis B vaccine, Mol. Pharmaceutics, 2011, 8, 405-415
    • (2011) Mol. Pharmaceutics , vol.8 , pp. 405-415
    • Thomas, C.1    Rawat, A.2    Hope-Weeks, L.3    Ahsan, F.4
  • 88
    • 58749108436 scopus 로고    scopus 로고
    • New approach on the development of a mucosal vaccine against strangles: Systemic and mucosal immune responses in a mouse model
    • H. F. Florindo, S. Pandit, L. M. Goncalves, H. O. Alpar, A. J. Almeida, New approach on the development of a mucosal vaccine against strangles: systemic and mucosal immune responses in a mouse model, Vaccine, 2009, 27, 1230-1241
    • (2009) Vaccine , vol.27 , pp. 1230-1241
    • Florindo, H.F.1    Pandit, S.2    Goncalves, L.M.3    Alpar, H.O.4    Almeida, A.J.5
  • 89
    • 0027437492 scopus 로고
    • The role of antigen-presenting cells in the regulation of delayed-type hypersensitivity. II. Epidermal Langerhans' cells and peritoneal exudate macrophages
    • Y. Morikawa, M. Furotani, N. Matsuura, K. Kakudo, The role of antigen-presenting cells in the regulation of delayed-type hypersensitivity. II. Epidermal Langerhans' cells and peritoneal exudate macrophages, Cell. Immunol. 1993, 152, 200-210
    • (1993) Cell. Immunol. , vol.152 , pp. 200-210
    • Morikawa, Y.1    Furotani, M.2    Matsuura, N.3    Kakudo, K.4
  • 90
    • 0025819491 scopus 로고
    • Murine Th1 and Th2 clones proliferate optimally in response to distinct antigen-presenting cell populations
    • T. F. Gajewski, M. Pinnas, T. Wong, F. W. Fitch, Murine Th1 and Th2 clones proliferate optimally in response to distinct antigen-presenting cell populations, J. Immunol. 1991, 146, 1750-1758
    • (1991) J. Immunol. , vol.146 , pp. 1750-1758
    • Gajewski, T.F.1    Pinnas, M.2    Wong, T.3    Fitch, F.W.4
  • 91
    • 84855726392 scopus 로고    scopus 로고
    • Pathological mechanisms of liver injury caused by continuous intraperitoneal injection of silica nanoparticles
    • T. Liu, L. Li, C. Fu, H. Liu, D. Chen, F. Tang, Pathological mechanisms of liver injury caused by continuous intraperitoneal injection of silica nanoparticles, Biomaterials, 2012, 33, 2399-2407
    • (2012) Biomaterials , vol.33 , pp. 2399-2407
    • Liu, T.1    Li, L.2    Fu, C.3    Liu, H.4    Chen, D.5    Tang, F.6
  • 92
    • 77149158798 scopus 로고    scopus 로고
    • Pulmonary inflammation after intraperitoneal administration of ultrafine titanium dioxide at rest or in lungs primed with lipopolysaccharide
    • C. Moon, H. J. Park, Y. H. Choi, E. M. Park, V. Castranova, J. L. Kang, Pulmonary inflammation after intraperitoneal administration of ultrafine titanium dioxide at rest or in lungs primed with lipopolysaccharide, J. Toxicol. Environ. Health, Part A, 2010, 73, 396-409
    • (2010) J. Toxicol. Environ. Health, Part A , vol.73 , pp. 396-409
    • Moon, C.1    Park, H.J.2    Choi, Y.H.3    Park, E.M.4    Castranova, V.5    Kang, J.L.6
  • 93
    • 71549145597 scopus 로고    scopus 로고
    • Nanosized titanium dioxide enhanced inflammatory responses in the septic brain of mouse
    • J. A. Shin, E. J. Lee, S. M. Seo, H. S. Kim, J. L. Kang, E. M. Park, Nanosized titanium dioxide enhanced inflammatory responses in the septic brain of mouse, Neuroscience, 2010, 165, 445-454
    • (2010) Neuroscience , vol.165 , pp. 445-454
    • Shin, J.A.1    Lee, E.J.2    Seo, S.M.3    Kim, H.S.4    Kang, J.L.5    Park, E.M.6
  • 94
    • 74549186977 scopus 로고    scopus 로고
    • Nano titanium dioxide particles promote allergic sensitization and lung inflammation in mice
    • S. T. Larsen, M. Roursgaard, K. A. Jensen, G. D. Nielsen, Nano titanium dioxide particles promote allergic sensitization and lung inflammation in mice, Basic Clin. Pharmacol. Toxicol. 2010, 106, 114-117
    • (2010) Basic Clin. Pharmacol. Toxicol , vol.106 , pp. 114-117
    • Larsen, S.T.1    Roursgaard, M.2    Jensen, K.A.3    Nielsen, G.D.4
  • 96
    • 78649770754 scopus 로고    scopus 로고
    • Antiviral and neuroprotective role of octaguanidinium dendrimer-conjugated morpholino oligomers in Japanese encephalitis
    • A. Nazmi, K. Dutta, A. Basu, Antiviral and neuroprotective role of octaguanidinium dendrimer-conjugated morpholino oligomers in Japanese encephalitis, PLoS Neglected Trop. Dis. 2010, 4, e892
    • (2010) Plos Neglected Trop. Dis. , vol.4 , pp. e892
    • Nazmi, A.1    Dutta, K.2    Basu, A.3
  • 97
    • 79955717998 scopus 로고    scopus 로고
    • Encapsulated in solid lipid nanoparticles induces substantial protection against Leishmania major infection in C57BL/6 mice
    • D. Doroud, F. Zahedifard, A. Vatanara, A. R. Najafabadi, S. Rafati, Cysteine proteinase type I, encapsulated in solid lipid nanoparticles induces substantial protection against Leishmania major infection in C57BL/6 mice, Parasite Immunol. 2011, 33, 335-348
    • (2011) Parasite Immunol. , vol.33 , pp. 335-348
    • Doroud, D.1    Zahedifard, F.2    Vatanara, A.3    Najafabadi, A.R.4    Rafati, S.5    Cysteine Proteinase Type, I.6
  • 98
    • 0033046220 scopus 로고    scopus 로고
    • Mechanisms of phagocytosis in macrophages
    • A. Aderem, D. M. Underhill, Mechanisms of phagocytosis in macrophages, Annu. Rev. Immunol. 1999, 17, 593-623
    • (1999) Annu. Rev. Immunol. , vol.17 , pp. 593-623
    • Aderem, A.1    Underhill, D.M.2
  • 99
    • 5444262511 scopus 로고    scopus 로고
    • Toll-like receptor control of the adaptive immune responses
    • A. Iwasaki, R. Medzhitov, Toll-like receptor control of the adaptive immune responses, Nat. Immunol. 2004, 5, 987-995
    • (2004) Nat. Immunol , vol.5 , pp. 987-995
    • Iwasaki, A.1    Medzhitov, R.2
  • 100
    • 20344389060 scopus 로고    scopus 로고
    • Toll-like receptors: Linking innate and adaptive immunity
    • C. Pasare, R. Medzhitov, Toll-like receptors: linking innate and adaptive immunity, Adv. Exp. Med. Biol. 2005, 560, 11-18
    • (2005) Adv. Exp. Med. Biol. , vol.560 , pp. 11-18
    • Pasare, C.1    Medzhitov, R.2
  • 101
    • 79952187464 scopus 로고    scopus 로고
    • Mechanistically probing lipid-siRNA nanoparticle-associated toxicities identifies Jak inhibitors effective in mitigating multifaceted toxic responses
    • W. Tao, X. Mao, J. P. Davide, B. Ng, M. Cai, P. A. Burke, A. B. Sachs, L. Sepp-Lorenzino, Mechanistically probing lipid-siRNA nanoparticle-associated toxicities identifies Jak inhibitors effective in mitigating multifaceted toxic responses, Mol. Ther. 2011, 19, 567-575
    • (2011) Mol. Ther. , vol.19 , pp. 567-575
    • Tao, W.1    Mao, X.2    Davide, J.P.3    Ng, B.4    Cai, M.5    Burke, P.A.6    Sachs, A.B.7    Sepp-Lorenzino, L.8
  • 102
    • 77951911814 scopus 로고    scopus 로고
    • Control of infection by pyroptosis and autophagy: Role of TLR and NLR
    • K. R. Bortoluci, R. Medzhitov, Control of infection by pyroptosis and autophagy: role of TLR and NLR, Cell. Mol. Life Sci. 2010, 67, 1643-1651
    • (2010) Cell. Mol. Life Sci. , vol.67 , pp. 1643-1651
    • Bortoluci, K.R.1    Medzhitov, R.2
  • 103
    • 33947202249 scopus 로고    scopus 로고
    • Nuclear factor-kappaB in development, prevention and therapy of cancer
    • C. Van Waes, Nuclear factor-kappaB in development, prevention and therapy of cancer, Clin. Cancer Res. 2007, 13, 1076-1082
    • (2007) Clin. Cancer Res. , vol.13 , pp. 1076-1082
    • Van Waes, C.1
  • 104
    • 33750074757 scopus 로고    scopus 로고
    • Receptor-mediated gene delivery into antigen presenting cells using mannosylated chitosan/DNA nanoparticles
    • T. H. Kim, J. W. Nah, M. H. Cho, T. G. Park, C. S. Cho, Receptor-mediated gene delivery into antigen presenting cells using mannosylated chitosan/DNA nanoparticles, J. Nanosci. Nanotechnol. 2006, 6, 2796-2803
    • (2006) J. Nanosci. Nanotechnol. , vol.6 , pp. 2796-2803
    • Kim, T.H.1    Nah, J.W.2    Cho, M.H.3    Park, T.G.4    Cho, C.S.5
  • 105
    • 84859830991 scopus 로고    scopus 로고
    • Tailoring the immune response by targeting C-type lectin receptors on alveolar macrophages using “pathogen-like” amphiphilic polyanhydride nanoparticles
    • A. V. Chavez-Santoscoy, R. Roychoudhury, N. L. Pohl, M. J. Wannemuehler, B. Narasimhan, A. E. Ramer-Tait, Tailoring the immune response by targeting C-type lectin receptors on alveolar macrophages using “pathogen-like” amphiphilic polyanhydride nanoparticles, Biomaterials, 2012, 33, 4762-4772
    • (2012) Biomaterials , vol.33 , pp. 4762-4772
    • Chavez-Santoscoy, A.V.1    Roychoudhury, R.2    Pohl, N.L.3    Wannemuehler, M.J.4    Narasimhan, B.5    Ramer-Tait, A.E.6
  • 107
    • 34447618774 scopus 로고    scopus 로고
    • Pharmaceutical analysis of synthetic lipid A-based vaccine adjuvants in poly (Dl-lactic-co-glycolic acid) nanoparticle formulations
    • S. Hamdy, A. Haddadi, V. Somayaji, D. Ruan, J. Samuel, Pharmaceutical analysis of synthetic lipid A-based vaccine adjuvants in poly (dl-lactic-co-glycolic acid) nanoparticle formulations, J. Pharm. Biomed. Anal. 2007, 44, 914-923
    • (2007) J. Pharm. Biomed. Anal. , vol.44 , pp. 914-923
    • Hamdy, S.1    Haddadi, A.2    Somayaji, V.3    Ruan, D.4    Samuel, J.5
  • 108
    • 78650606928 scopus 로고    scopus 로고
    • Nanoparticle-induced unfolding of fibrinogen promotes Mac-1 receptor activation and inflammation
    • Z. J. Deng, M. Liang, M. Monteiro, I. Toth, R. F. Minchin, Nanoparticle-induced unfolding of fibrinogen promotes Mac-1 receptor activation and inflammation, Nat. Nanotechnol. 2011, 6, 39-44
    • (2011) Nat. Nanotechnol. , vol.6 , pp. 39-44
    • Deng, Z.J.1    Liang, M.2    Monteiro, M.3    Toth, I.4    Minchin, R.F.5
  • 109
    • 14644400451 scopus 로고    scopus 로고
    • Immunostimulation mechanism of LPD nanoparticle as a vaccine carrier
    • Z. Cui, S. J. Han, D. P. Vangasseri, L. Huang, Immunostimulation mechanism of LPD nanoparticle as a vaccine carrier, Mol. Pharmaceutics, 2005, 2, 22-28
    • (2005) Mol. Pharmaceutics , vol.2 , pp. 22-28
    • Cui, Z.1    Han, S.J.2    Vangasseri, D.P.3    Huang, L.4
  • 110
    • 82355182186 scopus 로고    scopus 로고
    • Evaluation of the cytotoxic and inflammatory potential of differentially shaped zinc oxide nanoparticles
    • B. C. Heng, X. Zhao, E. C. Tan, N. Khamis, A. Assodani, S. Xiong, C. Ruedl, K. W. Ng, J. S. Loo, Evaluation of the cytotoxic and inflammatory potential of differentially shaped zinc oxide nanoparticles, Arch. Toxicol. 2011, 85, 1517-1528
    • (2011) Arch. Toxicol. , vol.85 , pp. 1517-1528
    • Heng, B.C.1    Zhao, X.2    Tan, E.C.3    Khamis, N.4    Assodani, A.5    Xiong, S.6    Ruedl, C.7    Ng, K.W.8    Loo, J.S.9
  • 111
    • 79954417654 scopus 로고    scopus 로고
    • Endocytosis and intracellular transport of nanoparticles: Present knowledge and need for future studies
    • T. G. Iversena, T. Skotlanda, K. Sandvig, Endocytosis and intracellular transport of nanoparticles: present knowledge and need for future studies, Nano Today, 2011, 6, 176-185
    • (2011) Nano Today , vol.6 , pp. 176-185
    • Iversena, T.G.1    Skotlanda, T.2    Sandvig, K.3
  • 113
    • 2442498325 scopus 로고    scopus 로고
    • Increased inflammation and altered macrophage chemotactic responses caused by two ultrafine particle types
    • L. C. Renwick, D. Brown, A. Clouter, K. Donaldson, Increased inflammation and altered macrophage chemotactic responses caused by two ultrafine particle types, Occup. Environ. Med. 2004, 61, 442-447
    • (2004) Occup. Environ. Med. , vol.61 , pp. 442-447
    • Renwick, L.C.1    Brown, D.2    Clouter, A.3    Donaldson, K.4
  • 114
    • 31944451232 scopus 로고    scopus 로고
    • Toxic potential of materials at the nanolevel
    • A. Nel, T. Xia, L. Madler, N. Li, Toxic potential of materials at the nanolevel, Science, 2006, 311, 622-627
    • (2006) Science , vol.311 , pp. 622-627
    • Nel, A.1    Xia, T.2    Madler, L.3    Li, N.4
  • 115
    • 20644449754 scopus 로고    scopus 로고
    • Nanotoxicology: An emerging discipline evolving from studies of ultrafine particles
    • G. Oberdorster, E. Oberdorster, J. Oberdorster, Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles, Environ. Health Perspect. 2005, 113, 823-839
    • (2005) Environ. Health Perspect. , vol.113 , pp. 823-839
    • Oberdorster, G.1    Oberdorster, E.2    Oberdorster, J.3
  • 116
    • 34548366466 scopus 로고    scopus 로고
    • The pro-inflammatory effects of low-toxicity low-solubility particles, nanoparticles and fine particles, on epithelial cells in vitro: The role of surface area
    • C. Monteiller, L. Tran, W. MacNee, S. Faux, A. Jones, B. Miller, K. Donaldson, The pro-inflammatory effects of low-toxicity low-solubility particles, nanoparticles and fine particles, on epithelial cells in vitro: the role of surface area, Occup. Environ. Med. 2007, 64, 609-615
    • (2007) Occup. Environ. Med. , vol.64 , pp. 609-615
    • Monteiller, C.1    Tran, L.2    Macnee, W.3    Faux, S.4    Jones, A.5    Miller, B.6    Donaldson, K.7
  • 117
    • 34447631504 scopus 로고    scopus 로고
    • Endocytosis, oxidative stress and IL-8 expression in human lung epithelial cells upon treatment with fine and ultrafine TiO ole of the specific surface area and of surface methylation of the particles
    • S. Singh, T. Shi, R. Duffin, C. Albrecht, D. van Berlo, D. Hohr, B. Fubini, G. Martra, I. Fenoglio, P. J. Borm, R. P. Schins, Endocytosis, oxidative stress and IL-8 expression in human lung epithelial cells upon treatment with fine and ultrafine TiO ole of the specific surface area and of surface methylation of the particles, Toxicol. Appl. Pharmacol. 2007, 222, 141-151
    • (2007) Toxicol. Appl. Pharmacol. , vol.222 , pp. 141-151
    • Singh, S.1    Shi, T.2    Duffin, R.3    Albrecht, C.4    Van Berlo, D.5    Hohr, D.6    Fubini, B.7    Martra, G.8    Fenoglio, I.9    Borm, P.J.10    Schins, R.P.11
  • 118
    • 33847068722 scopus 로고    scopus 로고
    • In search of the most relevant parameter for quantifying lung inflammatory response to nanoparticle exposure: Particle number, surface area, or what?
    • K. Wittmaack, In search of the most relevant parameter for quantifying lung inflammatory response to nanoparticle exposure: particle number, surface area, or what?, Environ. Health Perspect. 2007, 115, 187-194
    • (2007) Environ. Health Perspect. , vol.115 , pp. 187-194
    • Wittmaack, K.1
  • 119
    • 33645823891 scopus 로고    scopus 로고
    • Pulmonary instillation studies with nanoscale TiO rods and dots in rats: Toxicity is not dependent upon particle size and surface area
    • D. B. Warheit, T. R. Webb, C. M. Sayes, V. L. Colvin, K. L. Reed, Pulmonary instillation studies with nanoscale TiO rods and dots in rats: toxicity is not dependent upon particle size and surface area, Toxicol. Sci. 2006, 91, 227-236
    • (2006) Toxicol. Sci. , vol.91 , pp. 227-236
    • Warheit, D.B.1    Webb, T.R.2    Sayes, C.M.3    Colvin, V.L.4    Reed, K.L.5
  • 124
    • 0023938397 scopus 로고
    • Influence of hydrophobicity on the adjuvant effect of particulate polymeric adjuvants
    • J. Kreuter, E. Liehl, U. Berg, M. Soliva, P. P. Speiser, Influence of hydrophobicity on the adjuvant effect of particulate polymeric adjuvants, Vaccine, 1988, 6, 253-256
    • (1988) Vaccine , vol.6 , pp. 253-256
    • Kreuter, J.1    Liehl, E.2    Berg, U.3    Soliva, M.4    Speiser, P.P.5
  • 126
    • 84866144321 scopus 로고    scopus 로고
    • Endosomal escape and siRNA delivery with cationic shell crosslinked knedel-like nanoparticles with tunable buffering capacities
    • R. Shrestha, M. Elsabahy, S. Florez-Malaver, S. Samarajeewa, K. L. Wooley, Endosomal escape and siRNA delivery with cationic shell crosslinked knedel-like nanoparticles with tunable buffering capacities, Biomaterials, 2012, 33, 8557-8568
    • (2012) Biomaterials , vol.33 , pp. 8557-8568
    • Shrestha, R.1    Elsabahy, M.2    Florez-Malaver, S.3    Samarajeewa, S.4    Wooley, K.L.5
  • 127
    • 70349505735 scopus 로고    scopus 로고
    • TLR9-dependent systemic interferon-beta production by intravenous injection of plasmid DNA/cationic liposome complex in mice
    • H. Yoshida, M. Nishikawa, S. Yasuda, Y. Mizuno, H. Toyota, T. Kiyota, R. Takahashi, Y. Takakura, TLR9-dependent systemic interferon-beta production by intravenous injection of plasmid DNA/cationic liposome complex in mice, J. Gene Med. 2009, 11, 708-717
    • (2009) J. Gene Med. , vol.11 , pp. 708-717
    • Yoshida, H.1    Nishikawa, M.2    Yasuda, S.3    Mizuno, Y.4    Toyota, H.5    Kiyota, T.6    Takahashi, R.7    Takakura, Y.8
  • 128
    • 77953627757 scopus 로고    scopus 로고
    • Essential role for TLR9 in prime but not prime-boost plasmid DNA vaccination to activate dendritic cells and protect from lethal viral infection
    • D. Rottembourg, C. M. Filippi, D. Bresson, K. Ehrhardt, E. A. Estes, J. E. Oldham, M. G. von Herrath, Essential role for TLR9 in prime but not prime-boost plasmid DNA vaccination to activate dendritic cells and protect from lethal viral infection, J. Immunol. 2010, 184, 7100-7107
    • (2010) J. Immunol. , vol.184 , pp. 7100-7107
    • Rottembourg, D.1    Filippi, C.M.2    Bresson, D.3    Ehrhardt, K.4    Estes, E.A.5    Oldham, J.E.6    Von Herrath, M.G.7
  • 129
    • 2442705429 scopus 로고    scopus 로고
    • Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signaling through toll-like receptor 3
    • K. Kariko, P. Bhuyan, J. Capodici, D. Weissman, Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signaling through toll-like receptor 3, J. Immunol. 2004, 172, 6545-6549
    • (2004) J. Immunol. , vol.172 , pp. 6545-6549
    • Kariko, K.1    Bhuyan, P.2    Capodici, J.3    Weissman, D.4
  • 132
  • 136
    • 34249064319 scopus 로고    scopus 로고
    • RNA interference and innate immunity
    • M. Sioud, RNA interference and innate immunity, Adv. Drug Delivery Rev. 2007, 59, 153-163
    • (2007) Adv. Drug Delivery Rev. , vol.59 , pp. 153-163
    • Sioud, M.1
  • 137
    • 39449097277 scopus 로고    scopus 로고
    • Overcoming the innate immune response to small interfering RNA
    • A. Judge, I. MacLachlan, Overcoming the innate immune response to small interfering RNA, Hum. Gene Ther. 2008, 19, 111-124
    • (2008) Hum. Gene Ther. , vol.19 , pp. 111-124
    • Judge, A.1    Maclachlan, I.2
  • 139
    • 36549011746 scopus 로고    scopus 로고
    • Immune activation by siRNA/liposome complexes in mice is sequence-independent: Lack of a role for Toll-like receptor 3 signaling
    • J. Y. Kim, S. Choung, E. J. Lee, Y. J. Kim, Y. C. Choi, Immune activation by siRNA/liposome complexes in mice is sequence-independent: lack of a role for Toll-like receptor 3 signaling, Mol. Cells, 2007, 24, 247-254
    • (2007) Mol. Cells , vol.24 , pp. 247-254
    • Kim, J.Y.1    Choung, S.2    Lee, E.J.3    Kim, Y.J.4    Choi, Y.C.5
  • 140
    • 32944454941 scopus 로고    scopus 로고
    • Design of noninflammatory synthetic siRNA mediating potent gene silencing in vivo
    • A. D. Judge, G. Bola, A. C. Lee, I. MacLachlan, Design of noninflammatory synthetic siRNA mediating potent gene silencing in vivo, Mol. Ther. 2006, 13, 494-505
    • (2006) Mol. Ther. , vol.13 , pp. 494-505
    • Judge, A.D.1    Bola, G.2    Lee, A.C.3    Maclachlan, I.4
  • 141
    • 54249139512 scopus 로고    scopus 로고
    • Challenges and opportunities for local and systemic delivery of siRNA and antisense oligonucleotides
    • L. Sepp-Lorenzino, M. Ruddy, Challenges and opportunities for local and systemic delivery of siRNA and antisense oligonucleotides, Clin. Pharmacol. Ther. 2008, 84, 628-632
    • (2008) Clin. Pharmacol. Ther. , vol.84 , pp. 628-632
    • Sepp-Lorenzino, L.1    Ruddy, M.2
  • 144
    • 22344454846 scopus 로고    scopus 로고
    • Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA
    • A. D. Judge, V. Sood, J. R. Shaw, D. Fang, K. McClintock, I. MacLachlan, Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA, Nat. Biotechnol. 2005, 23, 457-462
    • (2005) Nat. Biotechnol. , vol.23 , pp. 457-462
    • Judge, A.D.1    Sood, V.2    Shaw, J.R.3    Fang, D.4    Mc Clintock, K.5    Maclachlan, I.6
  • 146
    • 0033600733 scopus 로고    scopus 로고
    • The mode of action of taxol: Apoptosis at low concentration and necrosis at high concentration
    • T. K. Yeung, C. Germond, X. Chen, Z. Wang, The mode of action of taxol: apoptosis at low concentration and necrosis at high concentration, Biochem. Biophys. Res. Commun. 1999, 263, 398-404
    • (1999) Biochem. Biophys. Res. Commun. , vol.263 , pp. 398-404
    • Yeung, T.K.1    Germond, C.2    Chen, X.3    Wang, Z.4
  • 152
    • 65749087491 scopus 로고    scopus 로고
    • In vitro assessments of nanomaterial toxicity
    • C. F. Jones, D. W. Grainger, In vitro assessments of nanomaterial toxicity, Adv. Drug Delivery Rev. 2009, 61, 438-456
    • (2009) Adv. Drug Delivery Rev. , vol.61 , pp. 438-456
    • Jones, C.F.1    Grainger, D.W.2
  • 153
    • 33748329694 scopus 로고    scopus 로고
    • The importance of an endotoxin-free environment during the production of nanoparticles used in medical applications
    • H. Vallhov, J. Qin, S. M. Johansson, N. Ahlborg, M. A. Muhammed, A. Scheynius, S. Gabrielsson, The importance of an endotoxin-free environment during the production of nanoparticles used in medical applications, Nano Lett. 2006, 6, 1682-1686
    • (2006) Nano Lett. , vol.6 , pp. 1682-1686
    • Vallhov, H.1    Qin, J.2    Johansson, S.M.3    Ahlborg, N.4    Muhammed, M.A.5    Scheynius, A.6    Gabrielsson, S.7
  • 154
    • 77953379662 scopus 로고    scopus 로고
    • Ambiguities in applying traditional Limulus amebocyte lysate tests to quantify endotoxin in nanoparticle formulations
    • M. A. Dobrovolskaia, B. W. Neun, J. D. Clogston, H. Ding, J. Ljubimova, S. E. McNeil, Ambiguities in applying traditional Limulus amebocyte lysate tests to quantify endotoxin in nanoparticle formulations, Nanomedicine, 2010, 5, 555-562
    • (2010) Nanomedicine , vol.5 , pp. 555-562
    • Dobrovolskaia, M.A.1    Neun, B.W.2    Clogston, J.D.3    Ding, H.4    Ljubimova, J.5    Mc Neil, S.E.6
  • 156
    • 78650657983 scopus 로고    scopus 로고
    • Particle length-dependent titanium dioxide nanomaterials toxicity and bioactivity, Pa
    • R. F. Hamilton, N. Wu, D. Porter, M. Buford, M. Wolfarth, A. Holian, Particle length-dependent titanium dioxide nanomaterials toxicity and bioactivity, Part. Fibre Toxicol. 2009, 6, 35
    • (2009) Fibre Toxicol. , vol.6 , pp. 35
    • Hamilton, R.F.1    Wu, N.2    Porter, D.3    Buford, M.4    Wolfarth, M.5    Holian, A.6
  • 157
    • 79952371250 scopus 로고    scopus 로고
    • Aggravating impact of nanoparticles on immune-mediated pulmonary inflammation
    • K. Inoue, H. Takano, Aggravating impact of nanoparticles on immune-mediated pulmonary inflammation, Sci. World J. 2011, 11, 382-390
    • (2011) Sci. World J. , vol.11 , pp. 382-390
    • Inoue, K.1    Takano, H.2
  • 160
    • 77951231991 scopus 로고    scopus 로고
    • Endotoxin promotes adverse effects of amorphous silica nanoparticles on lung epithelial cells in vitro
    • Y. Shi, S. Yadav, F. Wang, H. Wang, Endotoxin promotes adverse effects of amorphous silica nanoparticles on lung epithelial cells in vitro, J. Toxicol. Environ. Health, Part A, 2010, 73, 748-756
    • (2010) J. Toxicol. Environ. Health, Part A , vol.73 , pp. 748-756
    • Shi, Y.1    Yadav, S.2    Wang, F.3    Wang, H.4
  • 163
    • 33845410139 scopus 로고    scopus 로고
    • Carbon nanotubes show no sign of acute toxicity but induce intracellular reactive oxygen species in dependence on contaminants
    • K. Pulskamp, S. Diabate, H. F. Krug, Carbon nanotubes show no sign of acute toxicity but induce intracellular reactive oxygen species in dependence on contaminants, Toxicol. Lett. 2007, 168, 58-74
    • (2007) Toxicol. Lett. , vol.168 , pp. 58-74
    • Pulskamp, K.1    Diabate, S.2    Krug, H.F.3
  • 164
    • 77955906264 scopus 로고    scopus 로고
    • The nuclear factor NF-kappaB pathway in inflammation
    • T. Lawrence, The nuclear factor NF-kappaB pathway in inflammation, Cold Spring Harbor Perspect. Biol. 2009, 1, a001651
    • (2009) Cold Spring Harbor Perspect. Biol. , vol.1 , pp. a001651
    • Lawrence, T.1
  • 165
    • 36049033394 scopus 로고    scopus 로고
    • Signaling to NF-kappaB by Toll-like receptors
    • T. Kawai, S. Akira, Signaling to NF-kappaB by Toll-like receptors, Trends Mol. Med. 2007, 13, 460-469
    • (2007) Trends Mol. Med. , vol.13 , pp. 460-469
    • Kawai, T.1    Akira, S.2
  • 166
  • 168
    • 34247130944 scopus 로고    scopus 로고
    • Effects of glucocorticoids on inflammation and arthritis
    • E. F. Morand, Effects of glucocorticoids on inflammation and arthritis, Curr. Opin. Rheumatol. 2007, 19, 302-307
    • (2007) Curr. Opin. Rheumatol. , vol.19 , pp. 302-307
    • Morand, E.F.1
  • 169
    • 0344467109 scopus 로고    scopus 로고
    • Toll-like receptor signalling pathways as key targets for mediating the anti-inflammatory and immunosuppressive effects of glucocorticoids
    • P. N. Moynagh, Toll-like receptor signalling pathways as key targets for mediating the anti-inflammatory and immunosuppressive effects of glucocorticoids, J. Endocrinol. 2003, 179, 139-144
    • (2003) J. Endocrinol. , vol.179 , pp. 139-144
    • Moynagh, P.N.1
  • 170
    • 70350666201 scopus 로고    scopus 로고
    • Carbon black and titanium dioxide nanoparticles induce pro-inflammatory responses in bronchial epithelial cells: Need for multiparametric evaluation due to adsorption artifacts
    • S. Val, S. Hussain, S. Boland, R. Hamel, A. Baeza-Squiban, F. Marano, Carbon black and titanium dioxide nanoparticles induce pro-inflammatory responses in bronchial epithelial cells: need for multiparametric evaluation due to adsorption artifacts, Inhalation Toxicol. 2009, 21, 115-122
    • (2009) Inhalation Toxicol. , vol.21 , pp. 115-122
    • Val, S.1    Hussain, S.2    Boland, S.3    Hamel, R.4    Baeza-Squiban, A.5    Marano, F.6
  • 171
    • 33748746916 scopus 로고    scopus 로고
    • Multi-walled carbon nanotube exposure alters protein expression in human keratinocytes
    • F. A. Witzmann, N. A. Monteiro-Riviere, Multi-walled carbon nanotube exposure alters protein expression in human keratinocytes, Nanomedicine, 2006, 2, 158-168
    • (2006) Nanomedicine , vol.2 , pp. 158-168
    • Witzmann, F.A.1    Monteiro-Riviere, N.A.2
  • 173
    • 79955473746 scopus 로고    scopus 로고
    • Progress in understanding adjuvant immunotoxicity mechanisms
    • A. Batista-Duharte, E. B. Lindblad, E. Oviedo-Orta, Progress in understanding adjuvant immunotoxicity mechanisms, Toxicol. Lett. 2011, 203, 97-105
    • (2011) Toxicol. Lett. , vol.203 , pp. 97-105
    • Batista-Duharte, A.1    Lindblad, E.B.2    Oviedo-Orta, E.3
  • 174
    • 66949115247 scopus 로고    scopus 로고
    • A comparison of multiplex suspension array large-panel kits for profiling cytokines and chemokines in rheumatoid arthritis patients
    • I. H. Khan, V. V. Krishnan, M. Ziman, K. Janatpour, T. Wun, P. A. Luciw, J. Tuscano, A comparison of multiplex suspension array large-panel kits for profiling cytokines and chemokines in rheumatoid arthritis patients, Cytometry, Part B, 2009, 76, 159-168
    • (2009) Cytometry, Part B , vol.76 , pp. 159-168
    • Khan, I.H.1    Krishnan, V.V.2    Ziman, M.3    Janatpour, K.4    Wun, T.5    Luciw, P.A.6    Tuscano, J.7
  • 179
    • 84855878885 scopus 로고    scopus 로고
    • Differential pro-inflammatory effects of metal oxide nanoparticles and their soluble ions in vitro and in vivo; zinc and copper nanoparticles, but not their ions, recruit eosinophils to the lungs
    • W. S. Cho, R. Duffin, C. A. Poland, A. Duschl, G. J. Oostingh, W. Macnee, M. Bradley, I. L. Megson, K. Donaldson, Differential pro-inflammatory effects of metal oxide nanoparticles and their soluble ions in vitro and in vivo; zinc and copper nanoparticles, but not their ions, recruit eosinophils to the lungs, Nanotoxicology, 2012, 6, 22-35
    • (2012) Nanotoxicology , vol.6 , pp. 22-35
    • Cho, W.S.1    Duffin, R.2    Poland, C.A.3    Duschl, A.4    Oostingh, G.J.5    Macnee, W.6    Bradley, M.7    Megson, I.L.8    Donaldson, K.9
  • 181
    • 85035240165 scopus 로고    scopus 로고
    • S. E. McNeil, Human Press, New York
    • Characterization of nanoparticles intended for drug delivery, ed. S. E. McNeil, Human Press, New York, 2011
    • (2011)
  • 182
    • 84855785145 scopus 로고    scopus 로고
    • Nanotoxicology and in vitro studies: The need of the hour
    • S. Arora, J. M. Rajwade, K. M. Paknikar, Nanotoxicology and in vitro studies: the need of the hour, Toxicol. Appl. Pharmacol. 2012, 258, 151-165
    • (2012) Toxicol. Appl. Pharmacol , vol.258 , pp. 151-165
    • Arora, S.1    Rajwade, J.M.2    Paknikar, K.M.3
  • 183
    • 70350503605 scopus 로고    scopus 로고
    • Development of in vitro systems for nanotoxicology: Methodological considerations
    • V. Stone, H. Johnston, R. P. Schins, Development of in vitro systems for nanotoxicology: methodological considerations, Crit. Rev. Toxicol. 2009, 39, 613-626
    • (2009) Crit. Rev. Toxicol. , vol.39 , pp. 613-626
    • Stone, V.1    Johnston, H.2    Schins, R.P.3
  • 184
    • 67349284747 scopus 로고    scopus 로고
    • Current in vitro methods in nanoparticle risk assessment: Limitations and challenges
    • A. Kroll, M. H. Pillukat, D. Hahn, J. Schnekenburger, Current in vitro methods in nanoparticle risk assessment: limitations and challenges, Eur. J. Pharm. Biopharm. 2009, 72, 370-377
    • (2009) Eur. J. Pharm. Biopharm. , vol.72 , pp. 370-377
    • Kroll, A.1    Pillukat, M.H.2    Hahn, D.3    Schnekenburger, J.4
  • 185
    • 60749093701 scopus 로고    scopus 로고
    • Analytical methods to assess nanoparticle toxicity
    • B. J. Marquis, S. A. Love, K. L. Braun, C. L. Haynes, Analytical methods to assess nanoparticle toxicity, Analyst, 2009, 134, 425-439
    • (2009) Analyst , vol.134 , pp. 425-439
    • Marquis, B.J.1    Love, S.A.2    Braun, K.L.3    Haynes, C.L.4
  • 186
    • 52449104809 scopus 로고    scopus 로고
    • DNA vaccines: Ready for prime time?
    • M. A. Kutzler, D. B. Weiner, DNA vaccines: ready for prime time?, Nat. Rev. Genet. 2008, 9, 776-788
    • (2008) Nat. Rev. Genet. , vol.9 , pp. 776-788
    • Kutzler, M.A.1    Weiner, D.B.2
  • 188
    • 84892627484 scopus 로고    scopus 로고
    • Normal Physiological Levels of Human Cytokines Using Bio-Plex Pro™Cytokine Assays
    • P. Chapman, C. Reyes, V. Gupta, Normal Physiological Levels of Human Cytokines Using Bio-Plex Pro™Cytokine Assays, Bio-Rad Tech Note, 2010, 6029
    • (2010) Bio-Rad Tech Note , pp. 6029
    • Chapman, P.1    Reyes, C.2    Gupta, V.3
  • 190
    • 33644963942 scopus 로고    scopus 로고
    • Multiplex bead array assays: Performance evaluation and comparison of sensitivity to ELISA
    • M. F. Elshal, J. P. McCoy, Multiplex bead array assays: performance evaluation and comparison of sensitivity to ELISA, Methods, 2006, 38, 317-323
    • (2006) Methods , vol.38 , pp. 317-323
    • Elshal, M.F.1    Mc Coy, J.P.2
  • 191
    • 79960128592 scopus 로고    scopus 로고
    • A fluorescent microsphere-based method for assay of multiple analytes in plasma
    • O. K. Bernhard, R. A. Mathias, T. W. Barnes, R. J. Simpson, A fluorescent microsphere-based method for assay of multiple analytes in plasma, Methods Mol. Biol. 2011, 728, 195-206
    • (2011) Methods Mol. Biol. 2 , vol.728 , pp. 195-206
    • Bernhard, O.K.1    Mathias, R.A.2    Barnes, T.W.3    Simpson, R.J.4
  • 193
    • 0022178181 scopus 로고
    • Cachectin/tumor necrosis factor: Production, distribution and metabolic fate in vivo
    • B. A. Beutler, I. W. Milsark, A. Cerami, Cachectin/tumor necrosis factor: production, distribution and metabolic fate in vivo, J. Immunol. 1985, 135, 3972-3977
    • (1985) J. Immunol. , vol.135 , pp. 3972-3977
    • Beutler, B.A.1    Milsark, I.W.2    Cerami, A.3
  • 195
    • 37549010793 scopus 로고    scopus 로고
    • Differential binding of cytokines to environmentally relevant particles: A possible source for misinterpretation of in vitro results?
    • A. Kocbach, A. I. Totlandsdal, M. Lag, M. Refsnes, P. E. Schwarze, Differential binding of cytokines to environmentally relevant particles: a possible source for misinterpretation of in vitro results?, Toxicol. Lett. 2008, 176, 131-137
    • (2008) Toxicol. Lett. , vol.176 , pp. 131-137
    • Kocbach, A.1    Totlandsdal, A.I.2    Lag, M.3    Refsnes, M.4    Schwarze, P.E.5
  • 196
    • 33947413465 scopus 로고    scopus 로고
    • Cytokine responses of human lung cells (BEAS-2B) treated with micron-sized and nanoparticles of metal oxides compared to soil dusts
    • J. M. Veranth, E. G. Kaser, M. M. Veranth, M. Koch, G. S. Yost, Cytokine responses of human lung cells (BEAS-2B) treated with micron-sized and nanoparticles of metal oxides compared to soil dusts, Part. Fibre Toxicol. 2007, 4, 2
    • (2007) Part. Fibre Toxicol. , vol.4 , pp. 2
    • Veranth, J.M.1    Kaser, E.G.2    Veranth, M.M.3    Koch, M.4    Yost, G.S.5
  • 197
    • 80255132116 scopus 로고    scopus 로고
    • Effect of thiol functionalization on the hemo-compatibility of PLGA nanoparticles
    • Y. M. Thasneem, S. Sajeesh, C. P. Sharma, Effect of thiol functionalization on the hemo-compatibility of PLGA nanoparticles, J. Biomed. Mater. Res. Part A, 2011, 99, 607-617
    • (2011) J. Biomed. Mater. Res. Part A , vol.99 , pp. 607-617
    • Thasneem, Y.M.1    Sajeesh, S.2    Sharma, C.P.3
  • 198
    • 48449086770 scopus 로고    scopus 로고
    • Facile, efficient approach to accomplish tunable chemistries and variable biodistributions for shell cross-linked nanoparticles
    • G. Sun, A. Hagooly, J. Xu, A. M. Nystrom, Z. Li, R. Rossin, D. A. Moore, K. L. Wooley, M. J. Welch, Facile, efficient approach to accomplish tunable chemistries and variable biodistributions for shell cross-linked nanoparticles, Biomacromolecules, 2008, 9, 1997-2006
    • (2008) Biomacromolecules , vol.9 , pp. 1997-2006
    • Sun, G.1    Hagooly, A.2    Xu, J.3    Nystrom, A.M.4    Li, Z.5    Rossin, R.6    Moore, D.A.7    Wooley, K.L.8    Welch, M.J.9
  • 200
    • 35548931193 scopus 로고    scopus 로고
    • Structural effects on the biodistribution and positron emission tomography (PET) imaging of well-defined (64)Cu-labeled nanoparticles comprised of amphiphilic block graft copolymers
    • E. D. Pressly, R. Rossin, A. Hagooly, K. Fukukawa, B. W. Messmore, M. J. Welch, K. L. Wooley, M. S. Lamm, R. A. Hule, D. J. Pochan, C. J. Hawker, Structural effects on the biodistribution and positron emission tomography (PET) imaging of well-defined (64)Cu-labeled nanoparticles comprised of amphiphilic block graft copolymers, Biomacromolecules, 2007, 8, 3126-3134
    • (2007) Biomacromolecules , vol.8 , pp. 3126-3134
    • Pressly, E.D.1    Rossin, R.2    Hagooly, A.3    Fukukawa, K.4    Messmore, B.W.5    Welch, M.J.6    Wooley, K.L.7    Lamm, M.S.8    Hule, R.A.9    Pochan, D.J.10    Hawker, C.J.11
  • 201
    • 52049121804 scopus 로고    scopus 로고
    • An efficient and low immunostimulatory nanoparticle formulation for systemic siRNA delivery to the tumor
    • S. Chono, S. D. Li, C. C. Conwell, L. Huang, An efficient and low immunostimulatory nanoparticle formulation for systemic siRNA delivery to the tumor, J. Controlled Release, 2008, 131, 64-69
    • (2008) J. Controlled Release , vol.131 , pp. 64-69
    • Chono, S.1    Li, S.D.2    Conwell, C.C.3    Huang, L.4
  • 202
    • 42549142820 scopus 로고    scopus 로고
    • Efficient oncogene silencing and metastasis inhibition via systemic delivery of siRNA
    • S. D. Li, S. Chono, L. Huang, Efficient oncogene silencing and metastasis inhibition via systemic delivery of siRNA, Mol. Ther. 2008, 16, 942-946
    • (2008) Mol. Ther. , vol.16 , pp. 942-946
    • Li, S.D.1    Chono, S.2    Huang, L.3
  • 203
    • 77349109732 scopus 로고    scopus 로고
    • Biodegradable calcium phosphate nanoparticle with lipid coating for systemic siRNA delivery
    • J. Li, Y. C. Chen, Y. C. Tseng, S. Mozumdar, L. Huang, Biodegradable calcium phosphate nanoparticle with lipid coating for systemic siRNA delivery, J. Controlled Release, 2010, 142, 416-421
    • (2010) J. Controlled Release , vol.142 , pp. 416-421
    • Li, J.1    Chen, Y.C.2    Tseng, Y.C.3    Mozumdar, S.4    Huang, L.5
  • 204
    • 52049090811 scopus 로고    scopus 로고
    • Chemically modified siRNA: Tools and applications
    • J. K. Watts, G. F. Deleavey, M. J. Damha, Chemically modified siRNA: tools and applications, Drug Discovery Today, 2008, 13, 842-855
    • (2008) Drug Discovery Today , vol.13 , pp. 842-855
    • Watts, J.K.1    Deleavey, G.F.2    Damha, M.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.