Ambiguities in applying traditional limulus amebocyte lysate tests to quantify endotoxin in nanoparticle formulations

Nanomedicine

Volumn 5, Issue 4, 2010, Pages 555-562

  Dobrovolskaia, Marina A ^a   Neun, Barry W ^a   Clogston, Jeffrey D ^a   Ding, Hui ^b   Ljubimova, Julia ^b   McNeil, Scott E ^a  

^a SAIC FREDERICK INC   (United States)

^b CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

Endotoxin; In vitro assay; Interference; Limulus Amebocyte Lysate; Lipopolysaccharide; Nanoparticles; Rabbit pyrogen test

Indexed keywords

COLLOIDAL GOLD; ENDOTOXIN; MACROGOL; NANOPARTICLE; POLYAMIDOAMINE;

ANIMAL EXPERIMENT; ARTICLE; BACTERIUM CONTAMINATION; CONTROLLED STUDY; ENDOTOXIN DETECTION; INTERMETHOD COMPARISON; LIMULUS LYSATE TEST; NANOTECHNOLOGY; NONHUMAN; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; RABBIT; RABBIT PYROGEN TEST;

ANIMALS; ENDOTOXINS; EQUIPMENT AND SUPPLIES; HORSESHOE CRABS; KINETICS; LIGHT; NANOPARTICLES; NEPHELOMETRY AND TURBIDIMETRY; PHARMACEUTICAL PREPARATIONS; RABBITS; SCATTERING, RADIATION;

EID: 77953379662     PISSN: 17435889     EISSN: None     Source Type: Journal    
DOI: 10.2217/nnm.10.29     Document Type: Article

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