Comparison of non-crystalline silica nanoparticles in IL-1β release from macrophages

Particle and Fibre Toxicology

Volumn 9, Issue , 2012, Pages

  Sandberg, Wiggo J ^a   Låg, Marit ^a   Holme, Jørn A ^a   Friede, Bernd ^b   Gualtieri, Maurizio ^a,c   Kruszewski, Marcin ^d,e   Schwarze, Per E ^a   Skuland, Tonje ^a   Refsnes, Magne ^a  

^a NORWEGIAN INSTITUTE OF PUBLIC HEALTH   (Norway)

^b Elkem Carbon AS   (Norway)

^c UNIVERSITY OF MILANO BICOCCA   (Italy)

^d INSTITUTE OF NUCLEAR CHEMISTRY AND TECHNOLOGY   (Poland)

^e Institute of Rural H   (Poland)

Author keywords

IL 1 ; Inflammation; Macrophages; NALP3 inflammasome; Non crystalline and crystalline silica particles; Particle size; Particle uptake; Phagosomal destabilization

Indexed keywords

CASPASE INHIBITOR; CATHEPSIN B; CRYOPYRIN; INTERLEUKIN 1BETA; NALP3 RECEPTOR; NANOPARTICLE; NON CRYSTALLINE SILICA NANOPARTICLE; RECEPTOR; RNA; SILICON DIOXIDE; UNCLASSIFIED DRUG;

ACIDIFICATION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; ENDOSOME; ENZYME ACTIVITY; GENE SILENCING; IMMUNE RESPONSE; LUNG ALVEOLUS MACROPHAGE; MACROPHAGE ACTIVATION; MACROPHAGE FUNCTION; MOUSE; NONHUMAN; PARTICLE SIZE; PHAGOCYTOSIS; PRIORITY JOURNAL; RAT; SURFACE PROPERTY;

ANIMALS; BIOLOGICAL TRANSPORT; CELL LINE, TRANSFORMED; CELLS, CULTURED; INFLAMMASOMES; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MACROPHAGES; MACROPHAGES, ALVEOLAR; MALE; MICE; MOLECULAR CONFORMATION; NANOPARTICLES; PARTICLE SIZE; PHAGOSOMES; RATS; RATS, INBRED WKY; SILICON DIOXIDE; SURFACE PROPERTIES;

BACTERIA (MICROORGANISMS); RATTUS;

EID: 84864808636     PISSN: None     EISSN: 17438977     Source Type: Journal    
DOI: 10.1186/1743-8977-9-32     Document Type: Article

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