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Volumn , Issue , 2013, Pages

Metal dyshomeostasis and inflammation in Alzheimer's and Parkinson's diseases: Possible impact of environmental exposures

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEINS; ANTI-INFLAMMATORY AGENTS; CHRONIC INFLAMMATION; ENVIRONMENTAL EXPOSURE; GENE EXPRESSION ANALYSIS; LYSOSOMAL DEGRADATION; MICROGLIAL ACTIVATIONS; MITOCHONDRIAL DYSFUNCTION;

EID: 84877260347     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.1155/2013/726954     Document Type: Review
Times cited : (116)

References (209)
  • 1
    • 33746310315 scopus 로고    scopus 로고
    • Alzheimer's disease
    • DOI 10.1016/S0140-6736(06)69113-7, PII S0140673606691137
    • Blennow K., de Leon M. J., Zetterberg H., Alzheimer's disease. The Lancet 2006 368 9533 387 403 2-s2.0-33746310315 10.1016/S0140-6736(06)69113-7 (Pubitemid 44108123)
    • (2006) Lancet , vol.368 , Issue.9533 , pp. 387-403
    • Blennow, K.1    De Leon, M.J.2    Zetterberg, H.3
  • 2
    • 84863337843 scopus 로고    scopus 로고
    • Alzheimer mechanisms and therapeutic strategies
    • 10.1016/j.cell.2012.02.040
    • Huang Y. D., Mucke L., Alzheimer mechanisms and therapeutic strategies. Cell 2012 148 6 1204 1222 10.1016/j.cell.2012.02.040
    • (2012) Cell , vol.148 , Issue.6 , pp. 1204-1222
    • Huang, Y.D.1    Mucke, L.2
  • 3
    • 84866122213 scopus 로고    scopus 로고
    • Sting of Alzheimer's failures offset by upcoming prevention trials
    • 10.1038/nrd3842
    • Mullard A., Sting of Alzheimer's failures offset by upcoming prevention trials. Nature Reviews Drug Discovery 2012 11 9 657 660 10.1038/nrd3842
    • (2012) Nature Reviews Drug Discovery , vol.11 , Issue.9 , pp. 657-660
    • Mullard, A.1
  • 4
    • 84866456583 scopus 로고    scopus 로고
    • Preventing Alzheimer's disease
    • 10.1126/science.1228541
    • Selkoe D. J., Preventing Alzheimer's disease. Science 2012 337 6101 1488 1492 10.1126/science.1228541
    • (2012) Science , vol.337 , Issue.6101 , pp. 1488-1492
    • Selkoe, D.J.1
  • 5
    • 84860211520 scopus 로고    scopus 로고
    • Pharmacoeconomic considerations of treating patients with advanced Parkinson's disease
    • 10.1517/14656566.2012.677435
    • Reese J. P., Dams J., Winter Y., Balzer-Geldsetzer M., Oertel W. H., Dodel R., Pharmacoeconomic considerations of treating patients with advanced Parkinson's disease. Expert Opinion on Pharmacotherapy 2012 13 7 939 958 10.1517/14656566.2012.677435
    • (2012) Expert Opinion on Pharmacotherapy , vol.13 , Issue.7 , pp. 939-958
    • Reese, J.P.1    Dams, J.2    Winter, Y.3    Balzer-Geldsetzer, M.4    Oertel, W.H.5    Dodel, R.6
  • 6
    • 63649095770 scopus 로고    scopus 로고
    • Parkinson's disease and residential exposure to maneb and paraquat from agricultural applications in the central valley of California
    • 2-s2.0-63649095770 10.1093/aje/kwp006
    • Costello S., Cockburn M., Bronstein J., Zhang X., Ritz B., Parkinson's disease and residential exposure to maneb and paraquat from agricultural applications in the central valley of California. American Journal of Epidemiology 2009 169 8 919 926 2-s2.0-63649095770 10.1093/aje/kwp006
    • (2009) American Journal of Epidemiology , vol.169 , Issue.8 , pp. 919-926
    • Costello, S.1    Cockburn, M.2    Bronstein, J.3    Zhang, X.4    Ritz, B.5
  • 7
    • 58849164675 scopus 로고    scopus 로고
    • Parkinson-linked genes and toxins that affect neuronal cell death through the Bcl-2 family
    • 2-s2.0-58849164675 10.1089/ars.2008.2228
    • Ethell D. W., Fei Q., Parkinson-linked genes and toxins that affect neuronal cell death through the Bcl-2 family. Antioxidants & Redox Signaling 2009 11 3 529 540 2-s2.0-58849164675 10.1089/ars.2008.2228
    • (2009) Antioxidants & Redox Signaling , vol.11 , Issue.3 , pp. 529-540
    • Ethell, D.W.1    Fei, Q.2
  • 8
    • 29644447278 scopus 로고    scopus 로고
    • Rotenone model of Parkinson disease: Multiple brain mitochondria dysfunctions after short term systemic rotenone intoxication
    • DOI 10.1074/jbc.M508628200
    • Panov A., Dikalov S., Shalbuyeva N., Taylor G., Sherer T., Greenamyre J. T., Rotenone model of Parkinson disease: multiple brain mitochondria dysfunctions after short term systemic rotenone intoxication. Journal of Biological Chemistry 2005 280 51 42026 42035 2-s2.0-29644447278 10.1074/jbc.M508628200 (Pubitemid 43023171)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.51 , pp. 42026-42035
    • Panov, A.1    Dikalov, S.2    Shalbuyeva, N.3    Taylor, G.4    Sherer, T.5    Greenamyre, J.T.6
  • 9
    • 84877261702 scopus 로고    scopus 로고
    • From The Alzheimer'S Association I. 2013
    • Information from the Alzheimer's Association,. 2013, http://www.alz.org/
  • 12
    • 0031980065 scopus 로고    scopus 로고
    • Four-hydroxynonenal, a product of lipid peroxidation, is increased in the brain in Alzheimer's disease
    • DOI 10.1016/S0197-4580(98)00009-8, PII S0197458098000098
    • Markesbery W. R., Lovell M. A., Four-hydroxynonenal, a product of lipid peroxidation, is increased in the brain in Alzheimer's disease. Neurobiology of Aging 1998 19 1 33 36 2-s2.0-0031980065 10.1016/S0197-4580(98)00009-8 (Pubitemid 28167792)
    • (1998) Neurobiology of Aging , vol.19 , Issue.1 , pp. 33-36
    • Markesbery, W.R.1    Lovell, M.A.2
  • 14
    • 84868535759 scopus 로고    scopus 로고
    • Progressive multiple sclerosis: Pathology and pathogenesis
    • 10.1038/nrneurol.2012.168
    • Lassmann H., van Horssen J., Mahad D., Progressive multiple sclerosis: pathology and pathogenesis. Nature Reviews Neurology 2012 8 11 647 656 10.1038/nrneurol.2012.168
    • (2012) Nature Reviews Neurology , vol.8 , Issue.11 , pp. 647-656
    • Lassmann, H.1    Van Horssen, J.2    Mahad, D.3
  • 16
    • 84867213778 scopus 로고    scopus 로고
    • Neuroinflammation after traumatic brain injury: Opportunities for therapeutic intervention
    • 10.1016/j.bbi.2012.06.008
    • Kumar A., Loane D. J., Neuroinflammation after traumatic brain injury: opportunities for therapeutic intervention. Brain Behavior and Immunity 2012 26 8 1191 1201 10.1016/j.bbi.2012.06.008
    • (2012) Brain Behavior and Immunity , vol.26 , Issue.8 , pp. 1191-1201
    • Kumar, A.1    Loane, D.J.2
  • 17
    • 0029560332 scopus 로고
    • Reactive microglia in Creutzfeldt-Jakob disease
    • Muhleisen H., Gehrmann J., Meyermann R., Reactive microglia in Creutzfeldt-Jakob disease. Neuropathology and Applied Neurobiology 1995 21 6 505 517 2-s2.0-0029560332 10.1111/j.1365-2990.1995.tb01097.x (Pubitemid 26029124)
    • (1995) Neuropathology and Applied Neurobiology , vol.21 , Issue.6 , pp. 505-517
    • Muhleisen, H.1    Gehrmann, J.2    Meyermann, R.3
  • 19
    • 10844258104 scopus 로고    scopus 로고
    • Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
    • DOI 10.1126/science.1104742
    • Nemeth E., Tuttle M. S., Powelson J., Vaughn M. D., Donovan A., Ward D. M., Ganz T., Kaplan J., Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science 2004 306 5704 2090 2093 2-s2.0-10844258104 10.1126/science.1104742 (Pubitemid 40007660)
    • (2004) Science , vol.306 , Issue.5704 , pp. 2090-2093
    • Nemeth, E.1    Tuttle, M.S.2    Powelson, J.3    Vaughn, M.D.4    Donovan, A.5    Ward, D.M.6    Ganz, T.7    Kaplan, J.8
  • 24
    • 0032507975 scopus 로고    scopus 로고
    • Copper, iron and zinc in Alzheimer's disease senile plaques
    • DOI 10.1016/S0022-510X(98)00092-6, PII S0022510X98000926
    • Lovell M. A., Robertson J. D., Teesdale W. J., Campbell J. L., Markesbery W. R., Copper, iron and zinc in Alzheimer's disease senile plaques. Journal of the Neurological Sciences 1998 158 1 47 52 2-s2.0-0032507975 10.1016/S0022-510X(98)00092-6 (Pubitemid 28277534)
    • (1998) Journal of the Neurological Sciences , vol.158 , Issue.1 , pp. 47-52
    • Lovell, M.A.1    Robertson, J.D.2    Teesdale, W.J.3    Campbell, J.L.4    Markesbery, W.R.5
  • 25
    • 80051669619 scopus 로고    scopus 로고
    • The projected effect of risk factor reduction on Alzheimer's disease prevalence
    • 10.1016/S1474-4422(11)70072-2
    • Barnes D. E., Yaffe K., The projected effect of risk factor reduction on Alzheimer's disease prevalence. Lancet Neurology 2011 10 9 819 828 10.1016/S1474-4422(11)70072-2
    • (2011) Lancet Neurology , vol.10 , Issue.9 , pp. 819-828
    • Barnes, D.E.1    Yaffe, K.2
  • 28
    • 0037096251 scopus 로고    scopus 로고
    • A Novel Function of Monomeric Amyloid β-Protein Serving as an Antioxidant Molecule against Metal-Induced Oxidative Damage
    • Zou K., Gong J. S., Yanagisawa K., Michikawa M., A novel function of monomeric amyloid β -protein serving as an antioxidant molecule against metal-induced oxidative damage. Journal of Neuroscience 2002 22 12 4833 4841 2-s2.0-0037096251 (Pubitemid 37465598)
    • (2002) Journal of Neuroscience , vol.22 , Issue.12 , pp. 4833-4841
    • Zou, K.1    Gong, J.-S.2    Yanagisawa, K.3    Michikawa, M.4
  • 29
    • 84877269620 scopus 로고    scopus 로고
    • Information from Alzheimer Europe
    • Information from Alzheimer Europe,. 2013, http://www.alzheimer-europe. org/
    • (2013)
  • 32
    • 79959395494 scopus 로고    scopus 로고
    • Iron, zinc and copper in the Alzheimer's disease brain: A quantitative meta-analysis. Some insight on the influence of citation bias on scientific opinion
    • 2-s2.0-79959395494 10.1016/j.pneurobio.2011.05.001
    • Schrag M., Mueller C., Oyoyo U., Smith M. A., Kirsch W. M., Iron, zinc and copper in the Alzheimer's disease brain: a quantitative meta-analysis. Some insight on the influence of citation bias on scientific opinion. Progress in Neurobiology 2011 94 3 296 306 2-s2.0-79959395494 10.1016/j.pneurobio.2011.05. 001
    • (2011) Progress in Neurobiology , vol.94 , Issue.3 , pp. 296-306
    • Schrag, M.1    Mueller, C.2    Oyoyo, U.3    Smith, M.A.4    Kirsch, W.M.5
  • 33
    • 38649112930 scopus 로고    scopus 로고
    • Zinc-amyloid β interactions on a millisecond time-scale stabilize non-fibrillar Alzheimer-related species
    • DOI 10.1021/ja076282l
    • Noy D., Solomonov I., Sinkevich O., Arad T., Kjaer K., Sagi I., Zinc-amyloid β interactions on a millisecond time-scale stabilize non-fibrillar Alzheimer-related species. Journal of the American Chemical Society 2008 130 4 1376 1383 2-s2.0-38649112930 10.1021/ja076282l (Pubitemid 351171018)
    • (2008) Journal of the American Chemical Society , vol.130 , Issue.4 , pp. 1376-1383
    • Noy, D.1    Solomonov, I.2    Sinkevich, O.3    Arad, T.4    Kjaer, K.5    Sagi, I.6
  • 34
    • 84867574210 scopus 로고    scopus 로고
    • Luteolin reduces zinc-induced tau phosphorylation at Ser262/356 in an ROS-dependent manner in SH-SY5Y cells
    • 10.1007/s12011-012-9411-z
    • Zhou F. T., Chen S. R., Xiong J. P., Li Y. H., Qu L. N., Luteolin reduces zinc-induced tau phosphorylation at Ser262/356 in an ROS-dependent manner in SH-SY5Y cells. Biological Trace Element Research 2012 149 2 273 279 10.1007/s12011-012-9411-z
    • (2012) Biological Trace Element Research , vol.149 , Issue.2 , pp. 273-279
    • Zhou, F.T.1    Chen, S.R.2    Xiong, J.P.3    Li, Y.H.4    Qu, L.N.5
  • 35
  • 39
    • 84961042345 scopus 로고
    • The effect of age on the non-haemin iron in the human brain
    • 10.1111/j.1471-4159.1958.tb12607.x
    • Hallgren B., Sourander P., The effect of age on the non-haemin iron in the human brain. Journal of Neurochemistry 1958 3 41 51 10.1111/j.1471-4159. 1958.tb12607.x
    • (1958) Journal of Neurochemistry , vol.3 , pp. 41-51
    • Hallgren, B.1    Sourander, P.2
  • 40
    • 0027932255 scopus 로고
    • Iron, transferrin, and ferritin in the rat brain during development and aging
    • Jane A., Roskams I., Connor J. R., Iron, transferrin, and ferritin in the rat brain during development and aging. Journal of Neurochemistry 1994 63 2 709 716 2-s2.0-0027932255 (Pubitemid 24233709)
    • (1994) Journal of Neurochemistry , vol.63 , Issue.2 , pp. 709-716
    • Jane, A.1    Roskams, I.2    Connor, J.R.3
  • 41
    • 51449110339 scopus 로고    scopus 로고
    • Iron accumulation with age, oxidative stress and functional decline
    • 2-s2.0-51449110339 10.1371/journal.pone.0002865 e2865
    • Xu J., Knutson M. D., Carter C. S., Leeuwenburgh C., Iron accumulation with age, oxidative stress and functional decline. PLoS ONE 2008 3 8 2-s2.0-51449110339 10.1371/journal.pone.0002865 e2865
    • (2008) PLoS ONE , vol.3 , Issue.8
    • Xu, J.1    Knutson, M.D.2    Carter, C.S.3    Leeuwenburgh, C.4
  • 42
    • 43849083422 scopus 로고    scopus 로고
    • Increased iron content and RNA oxidative damage in skeletal muscle with aging and disuse atrophy
    • 2-s2.0-43849083422 10.1016/j.exger.2008.02.007
    • Hofer T., Marzetti E., Xu J., Seo A. Y., Gulec S., Knutson M. D., Leeuwenburgh C., Dupont-Versteegden E. E., Increased iron content and RNA oxidative damage in skeletal muscle with aging and disuse atrophy. Experimental Gerontology 2008 43 6 563 570 2-s2.0-43849083422 10.1016/j.exger.2008.02.007
    • (2008) Experimental Gerontology , vol.43 , Issue.6 , pp. 563-570
    • Hofer, T.1    Marzetti, E.2    Xu, J.3    Seo, A.Y.4    Gulec, S.5    Knutson, M.D.6    Leeuwenburgh, C.7    Dupont-Versteegden, E.E.8
  • 43
    • 4944261763 scopus 로고    scopus 로고
    • Prevalence of anemia in persons 65 years and older in the United States: Evidence for a high rate of unexplained anemia
    • DOI 10.1182/blood-2004-05-1812
    • Guralnik J. M., Eisenstaedt R. S., Ferrucci L., Klein H. G., Woodman R. C., Prevalence of anemia in persons 65 years and older in the United States: evidence for a high rate of unexplained anemia. Blood 2004 104 8 2263 2268 2-s2.0-4944261763 10.1182/blood-2004-05-1812 (Pubitemid 39331821)
    • (2004) Blood , vol.104 , Issue.8 , pp. 2263-2268
    • Guralnik, J.M.1    Eisenstaedt, R.S.2    Ferrucci, L.3    Klein, H.G.4    Woodman, R.C.5
  • 44
    • 47949130644 scopus 로고    scopus 로고
    • Lipopolysaccharide induces a significant increase in expression of iron regulatory hormone hepcidin in the cortex and substantia nigra in rat brain
    • 2-s2.0-47949130644 10.1210/en.2007-1626
    • Wang Q., Du F., Qian Z. M., Xiao H. G., Zhu L., Wing H. Y., Yang L., Ke Y., Lipopolysaccharide induces a significant increase in expression of iron regulatory hormone hepcidin in the cortex and substantia nigra in rat brain. Endocrinology 2008 149 8 3920 3925 2-s2.0-47949130644 10.1210/en.2007-1626
    • (2008) Endocrinology , vol.149 , Issue.8 , pp. 3920-3925
    • Wang, Q.1    Du, F.2    Qian, Z.M.3    Xiao, H.G.4    Zhu, L.5    Wing, H.Y.6    Yang, L.7    Ke, Y.8
  • 46
    • 84868526205 scopus 로고    scopus 로고
    • Hepcidin and the iron-infection axis
    • 10.1126/science.1224577
    • Drakesmith H., Prentice A. M., Hepcidin and the iron-infection axis. Science 2012 338 S768 S772 10.1126/science.1224577
    • (2012) Science , vol.338
    • Drakesmith, H.1    Prentice, A.M.2
  • 47
    • 84861355868 scopus 로고    scopus 로고
    • Hepcidin and iron homeostasis
    • 10.1016/j.bbamcr.2012.01.014
    • Ganz T., Nemeth E., Hepcidin and iron homeostasis. Biochimica et Biophysica Acta 2012 1823 9 1434 1443 10.1016/j.bbamcr.2012.01.014
    • (2012) Biochimica et Biophysica Acta , vol.1823 , Issue.9 , pp. 1434-1443
    • Ganz, T.1    Nemeth, E.2
  • 49
    • 84863008910 scopus 로고    scopus 로고
    • High hepcidin level accounts for the nigral iron accumulation in acute peripheral iron intoxication rats
    • 10.1016/j.toxlet.2012.05.022
    • Sun C., Song N., Xie A. M., Xie J. X., Jiang H., High hepcidin level accounts for the nigral iron accumulation in acute peripheral iron intoxication rats. Toxicology Letters 2012 212 3 276 281 10.1016/j.toxlet.2012.05.022
    • (2012) Toxicology Letters , vol.212 , Issue.3 , pp. 276-281
    • Sun, C.1    Song, N.2    Xie, A.M.3    Xie, J.X.4    Jiang, H.5
  • 50
    • 82455192361 scopus 로고    scopus 로고
    • Hepcidin treatment modulates the expression of divalent metal transporter-1, ceruloplasmin, and ferroportin-1 in the rat cerebral cortex and hippocampus
    • 10.1007/s12011-011-8967-3
    • Li L., Holscher C., Chen B. B., Zhang Z. F., Liu Y. Z., Hepcidin treatment modulates the expression of divalent metal transporter-1, ceruloplasmin, and ferroportin-1 in the rat cerebral cortex and hippocampus. Biological Trace Element Research 2011 143 3 1581 1593 10.1007/s12011-011-8967-3
    • (2011) Biological Trace Element Research , vol.143 , Issue.3 , pp. 1581-1593
    • Li, L.1    Holscher, C.2    Chen, B.B.3    Zhang, Z.F.4    Liu, Y.Z.5
  • 51
    • 84864053080 scopus 로고    scopus 로고
    • Induction of activin B by inflammatory stimuli up-regulates expression of the iron-regulatory peptide hepcidin through Smad1/5/8 signaling
    • 10.1182/blood-2012-02-411470
    • Besson-Fournier C., Latour C., Kautz L., Bertrand J., Ganz T., Roth M. P., Coppin H., Induction of activin B by inflammatory stimuli up-regulates expression of the iron-regulatory peptide hepcidin through Smad1/5/8 signaling. Blood 2012 120 2 431 439 10.1182/blood-2012-02-411470
    • (2012) Blood , vol.120 , Issue.2 , pp. 431-439
    • Besson-Fournier, C.1    Latour, C.2    Kautz, L.3    Bertrand, J.4    Ganz, T.5    Roth, M.P.6    Coppin, H.7
  • 54
    • 0030036172 scopus 로고    scopus 로고
    • Ceruloplasmin gene expression in the murine central nervous system
    • Klomp L. W. J., Farhangrazi Z. S., Dugan L. L., Gitlin J. D., Ceruloplasmin gene expression in the murine central nervous system. Journal of Clinical Investigation 1996 98 1 207 215 2-s2.0-0030036172 10.1172/JCI118768 (Pubitemid 26243838)
    • (1996) Journal of Clinical Investigation , vol.98 , Issue.1 , pp. 207-215
    • Klomp, L.W.J.1    Farhangrazi, Z.S.2    Dugan, L.L.3    Gitlin, J.D.4
  • 55
    • 77955092432 scopus 로고    scopus 로고
    • Zinc prevents the copper-induced damage of cultured astrocytes
    • 2-s2.0-77955092432 10.1016/j.neuint.2010.06.010
    • Scheiber I. F., Schmidt M. M., Dringen R., Zinc prevents the copper-induced damage of cultured astrocytes. Neurochemistry International 2010 57 3 314 322 2-s2.0-77955092432 10.1016/j.neuint.2010.06.010
    • (2010) Neurochemistry International , vol.57 , Issue.3 , pp. 314-322
    • Scheiber, I.F.1    Schmidt, M.M.2    Dringen, R.3
  • 56
    • 0037160028 scopus 로고    scopus 로고
    • Overexpression of Alzheimer's disease amyloid-β opposes the age-dependent elevations of brain copper and iron
    • DOI 10.1074/jbc.M204379200
    • Maynard C. J., Cappai R., Volitakis I., Cherny R. A., White A. R., Beyreuther K., Masters C. L., Bush A. I., Li Q. X., Overexpression of Alzheimer's disease amyloid- β opposes the age-dependent elevations of brain copper and iron. Journal of Biological Chemistry 2002 277 47 44670 44676 2-s2.0-0037160028 10.1074/jbc.M204379200 (Pubitemid 36159056)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.47 , pp. 44670-44676
    • Maynard, C.J.1    Cappai, R.2    Volitakis, I.3    Cherny, R.A.4    White, A.R.5    Beyreuther, K.6    Masters, C.L.7    Bush, A.I.8    Li, Q.-X.9
  • 57
    • 39849096023 scopus 로고    scopus 로고
    • Alzheimer's disease as copper deficiency
    • DOI 10.1016/j.mehy.2007.04.051, PII S0306987707005270
    • Klevay L. M., Alzheimer's disease as copper deficiency. Medical Hypotheses 2008 70 4 802 807 2-s2.0-39849096023 10.1016/j.mehy.2007.04.051 (Pubitemid 351318084)
    • (2008) Medical Hypotheses , vol.70 , Issue.4 , pp. 802-807
    • Klevay, L.M.1
  • 58
    • 0034612075 scopus 로고    scopus 로고
    • A selective defect of cytochrome c oxidase is present in brain of Alzheimer disease patients
    • DOI 10.1016/S0197-4580(00)00112-3, PII S0197458000001123
    • Maurer I., Zierz S., Möller H. J., A selective defect of cytochrome c oxidase is present in brain of Alzheimer disease patients. Neurobiology of Aging 2000 21 3 455 462 2-s2.0-0034612075 10.1016/S0197-4580(00)00112-3 (Pubitemid 30349116)
    • (2000) Neurobiology of Aging , vol.21 , Issue.3 , pp. 455-462
    • Maurer, I.1    Zierz, S.2    Moller, H.-J.3
  • 59
    • 48449094910 scopus 로고    scopus 로고
    • Free copper, ferroxidase and SOD1 activities, lipid peroxidation and NOx content in the CSF. A different marker profile in four neurodegenerative diseases
    • 2-s2.0-48449094910 10.1007/s11064-008-9610-3
    • Boll M. C., Alcaraz-Zubeldia M., Montes S., Rios C., Free copper, ferroxidase and SOD1 activities, lipid peroxidation and NOx content in the CSF. A different marker profile in four neurodegenerative diseases. Neurochemical Research 2008 33 9 1717 1723 2-s2.0-48449094910 10.1007/s11064-008-9610-3
    • (2008) Neurochemical Research , vol.33 , Issue.9 , pp. 1717-1723
    • Boll, M.C.1    Alcaraz-Zubeldia, M.2    Montes, S.3    Rios, C.4
  • 62
    • 49349097514 scopus 로고    scopus 로고
    • Age-related differences in NF B translocation and Bcl-2/Bax ratio caused by TNF α and Abeta42 promote survival in middle-age neurons and death in old neurons
    • 2-s2.0-49349097514 10.1016/j.expneurol.2008.05.007
    • Patel J. R., Brewer G. J., Age-related differences in NF B translocation and Bcl-2/Bax ratio caused by TNF α and Abeta42 promote survival in middle-age neurons and death in old neurons. Experimental Neurology 2008 213 1 93 100 2-s2.0-49349097514 10.1016/j.expneurol.2008.05.007
    • (2008) Experimental Neurology , vol.213 , Issue.1 , pp. 93-100
    • Patel, J.R.1    Brewer, G.J.2
  • 63
    • 77950363010 scopus 로고    scopus 로고
    • Mechanisms underlying inflammation in neurodegeneration
    • 2-s2.0-77950363010 10.1016/j.cell.2010.02.016
    • Glass C. K., Saijo K., Winner B., Marchetto M. C., Gage F. H., Mechanisms underlying inflammation in neurodegeneration. Cell 2010 140 6 918 934 2-s2.0-77950363010 10.1016/j.cell.2010.02.016
    • (2010) Cell , vol.140 , Issue.6 , pp. 918-934
    • Glass, C.K.1    Saijo, K.2    Winner, B.3    Marchetto, M.C.4    Gage, F.H.5
  • 64
    • 25144486774 scopus 로고    scopus 로고
    • Hydrogen peroxide causes greater oxidation in cellular RNA than in DNA
    • DOI 10.1515/BC.2005.040
    • Hofer T., Badouard C., Bajak E., Ravanat J. L., Mattsson Å., Cotgreave I. A., Hydrogen peroxide causes greater oxidation in cellular RNA than in DNA. Biological Chemistry 2005 386 4 333 337 2-s2.0-25144486774 10.1515/BC.2005.040 (Pubitemid 41460233)
    • (2005) Biological Chemistry , vol.386 , Issue.4 , pp. 333-337
    • Hofer, T.1    Badouard, C.2    Bajak, E.3    Ravanat, J.-L.4    Mattsson, A.5    Cotgreave, I.A.6
  • 66
    • 67349251839 scopus 로고    scopus 로고
    • RNA oxidation in Alzheimer disease and related neurodegenerative disorders
    • 2-s2.0-67349251839 10.1007/s00401-009-0508-1
    • Nunomura A., Hofer T., Moreira P. I., Castellani R. J., Smith M. A., Perry G., RNA oxidation in Alzheimer disease and related neurodegenerative disorders. Acta Neuropathologica 2009 118 1 151 166 2-s2.0-67349251839 10.1007/s00401-009-0508-1
    • (2009) Acta Neuropathologica , vol.118 , Issue.1 , pp. 151-166
    • Nunomura, A.1    Hofer, T.2    Moreira, P.I.3    Castellani, R.J.4    Smith, M.A.5    Perry, G.6
  • 69
    • 23844448026 scopus 로고    scopus 로고
    • 4-Oxo-2-nonenal is both more neurotoxic and more protein reactive than 4-hydroxy-2-nonenal
    • DOI 10.1021/tx050080q
    • Lin D., Lee H. G., Liu Q., Perry G., Smith M. A., Sayre L. M., 4-Oxo-2-nonenal is both more neurotoxic and more protein reactive than 4-hydroxy-2-nonenal. Chemical Research in Toxicology 2005 18 8 1219 1231 2-s2.0-23844448026 10.1021/tx050080q (Pubitemid 41170246)
    • (2005) Chemical Research in Toxicology , vol.18 , Issue.8 , pp. 1219-1231
    • Lin, D.1    Lee, H.-G.2    Liu, Q.3    Perry, G.4    Smith, M.A.5    Sayre, L.M.6
  • 70
    • 79952113682 scopus 로고    scopus 로고
    • Carbonyl proteins as a clinical marker in Alzheimer's disease and its relation to tryptophan degradation and immune activation
    • 2-s2.0-79952113682
    • Greilberger J., Fuchs D., Leblhuber F., Greilberger M., Wintersteiger R., Tafeit E., Carbonyl proteins as a clinical marker in Alzheimer's disease and its relation to tryptophan degradation and immune activation. Clinical Laboratory 2010 56 9-10 441 448 2-s2.0-79952113682
    • (2010) Clinical Laboratory , vol.56 , Issue.9-10 , pp. 441-448
    • Greilberger, J.1    Fuchs, D.2    Leblhuber, F.3    Greilberger, M.4    Wintersteiger, R.5    Tafeit, E.6
  • 71
    • 0031776586 scopus 로고    scopus 로고
    • Cytochemical demonstration of oxidative damage in Alzheimer disease by immunochemical enhancement of the carbonyl reaction with 2,4- dinitrophenylhydrazine
    • Smith M. A., Sayre L. M., Anderson V. E., Harris P. L. R., Beal M. F., Kowall N., Perry G., Cytochemical demonstration of oxidative damage in Alzheimer disease by immunochemical enhancement of the carbonyl reaction with 2,4- dinitrophenylhydrazine. Journal of Histochemistry & Cytochemistry 1998 46 6 731 735 2-s2.0-0031776586 10.1177/002215549804600605 (Pubitemid 28272207)
    • (1998) Journal of Histochemistry and Cytochemistry , vol.46 , Issue.6 , pp. 731-735
    • Smith, M.A.1    Sayre, L.M.2    Anderson, V.E.3    Harris, P.L.R.4    Beal, M.F.5    Kowall, N.6    Perry, G.7
  • 72
    • 0036081355 scopus 로고    scopus 로고
    • Gene Expression Omnibus: NCBI gene expression and hybridization array data repository
    • Edgar R., Domrachev M., Lash A. E., Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Research 2002 30 1 207 210 2-s2.0-0036081355 10.1093/nar/30.1.207 (Pubitemid 34679544)
    • (2002) Nucleic Acids Research , vol.30 , Issue.1 , pp. 207-210
    • Edgar, R.1    Domrachev, M.2    Lash, A.E.3
  • 75
    • 34748915836 scopus 로고    scopus 로고
    • Molecular portrait of cisplatin induced response in human testis cancer cell lines based on gene expression profiles
    • DOI 10.1186/1476-4598-6-53
    • Duale N., Lindeman B., Komada M., Olsen A. K., Andreassen A., Soderlund E. J., Brunborg G., Molecular portrait of cisplatin induced response in human testis cancer cell lines based on gene expression profiles. Molecular Cancer 2007 6, article 53 2-s2.0-34748915836 10.1186/1476-4598-6-53 (Pubitemid 47471190)
    • (2007) Molecular Cancer , vol.6 , pp. 53
    • Duale, N.1    Lindeman, B.2    Komada, M.3    Olsen, A.-K.4    Andreassen, A.5    Soderlund, E.J.6    Brunborg, G.7
  • 76
    • 0035021690 scopus 로고    scopus 로고
    • J-Express: Exploring gene expression data using Java
    • Dysvik B., Jonassen I., J-Express: exploring gene expression data using Java. Bioinformatics 2001 17 4 369 370 2-s2.0-0035021690 10.1093/bioinformatics/ 17.4.369 (Pubitemid 32421932)
    • (2001) Bioinformatics , vol.17 , Issue.4 , pp. 369-370
    • Dysvik, B.1    Jonassen, I.2
  • 79
    • 84861467439 scopus 로고    scopus 로고
    • A proteomic analysis of MCLR-induced neurotoxicity: Implications for Alzheimer's disease
    • 10.1093/toxsci/kfs114
    • Li G. Y., Cai F., Yan W., Li C. R., Wang J. H., A proteomic analysis of MCLR-induced neurotoxicity: implications for Alzheimer's disease. Toxicological Sciences 2012 127 2 485 495 10.1093/toxsci/kfs114
    • (2012) Toxicological Sciences , vol.127 , Issue.2 , pp. 485-495
    • Li, G.Y.1    Cai, F.2    Yan, W.3    Li, C.R.4    Wang, J.H.5
  • 81
    • 0345255588 scopus 로고    scopus 로고
    • Biomagnification of cyanobacterial neurotoxins and neurodegenerative disease among the Chamorro people of Guam
    • DOI 10.1073/pnas.2235808100
    • Cox P. A., Banack S. A., Murch S. J., Biomagnification of cyanobacterial neurotoxins and neurodegenerative disease among the Chamorro people of Guam. Proceedings of the National Academy of Sciences of the United States of America 2003 100 23 13380 13383 2-s2.0-0345255588 10.1073/pnas.2235808100 (Pubitemid 37444750)
    • (2003) Proceedings of the National Academy of Sciences of the United States of America , vol.100 , Issue.23 , pp. 13380-13383
    • Cox, P.A.1    Banack, S.A.2    Murch, S.J.3
  • 83
    • 81855168337 scopus 로고    scopus 로고
    • Microcystin congener- and concentration-dependent induction of murine neuron apoptosis and neurite degeneration
    • 10.1093/toxsci/kfr243
    • Feurstein D., Stemmer K., Kleinteich J., Speicher T., Dietrich D. R., Microcystin congener- and concentration-dependent induction of murine neuron apoptosis and neurite degeneration. Toxicological Sciences 2011 124 2 424 431 10.1093/toxsci/kfr243
    • (2011) Toxicological Sciences , vol.124 , Issue.2 , pp. 424-431
    • Feurstein, D.1    Stemmer, K.2    Kleinteich, J.3    Speicher, T.4    Dietrich, D.R.5
  • 84
    • 0141626442 scopus 로고    scopus 로고
    • Health hazards for terrestrial vertebrates from toxic cyanobacteria in surface water ecosystems
    • DOI 10.1051/vetres:2003019
    • Briand J. F., Jacquet S., Bernard C., Humbert J. F., Health hazards for terrestrial vertebrates from toxic cyanobacteria in surface water ecosystems. Veterinary Research 2003 34 4 361 377 2-s2.0-0141626442 10.1051/vetres:2003019 (Pubitemid 37121280)
    • (2003) Veterinary Research , vol.34 , Issue.4 , pp. 361-377
    • Briand, J.-F.1    Jacquet, S.2    Bernard, C.3    Humbert, J.-F.4
  • 85
    • 45549099258 scopus 로고    scopus 로고
    • Cyanobacterial poisoning in livestock, wild mammals and birds - An overview
    • 2-s2.0-45549099258 10.1007/978-0-387-75865-7-28
    • Stewart I., Seawright A. A., Shaw G. R., Cyanobacterial poisoning in livestock, wild mammals and birds-an overview. Advances in Experimental Medicine and Biology 2008 619 613 637 2-s2.0-45549099258 10.1007/978-0-387-75865-7-28
    • (2008) Advances in Experimental Medicine and Biology , vol.619 , pp. 613-637
    • Stewart, I.1    Seawright, A.A.2    Shaw, G.R.3
  • 89
    • 84934436178 scopus 로고    scopus 로고
    • Toxin mixture in cyanobacterial blooms - A critical comparison of reality with current procedures employed in human health risk assessment
    • 2-s2.0-45549087136 10.1007/978-0-387-75865-7-39
    • Dietrich D. R., Fischer A., Michel C., Hoeger S., Toxin mixture in cyanobacterial blooms-a critical comparison of reality with current procedures employed in human health risk assessment. Advances in Experimental Medicine and Biology 2008 619 885 912 2-s2.0-45549087136 10.1007/978-0-387-75865-7-39
    • (2008) Advances in Experimental Medicine and Biology , vol.619 , pp. 885-912
    • Dietrich, D.R.1    Fischer, A.2    Michel, C.3    Hoeger, S.4
  • 90
    • 0025188759 scopus 로고
    • Synthesis, organotropism and hepatocellular uptake of two tritium-labeled epimers of dihydromicrocystin-LR, a cyanobacterial peptide toxin analog
    • DOI 10.1016/0041-0101(90)90157-3
    • Meriluoto J. A. O., Nygard S. E., Dahlem A. M., Eriksson J. E., Synthesis, organotropism and hepatocellular uptake of two tritium-labeled epimers of dihydromicrocystin-LR, a cyanobacterial peptide toxin analog. Toxicon 1990 28 12 1439 1446 2-s2.0-0025188759 10.1016/0041-0101(90)90157-3 (Pubitemid 20383754)
    • (1990) Toxicon , vol.28 , Issue.12 , pp. 1439-1446
    • Meriluoto, J.A.O.1    Nygard, S.E.2    Dahlem, A.M.3    Eriksson, J.E.4
  • 92
    • 84863896457 scopus 로고    scopus 로고
    • The novel multi-target iron chelating-radical scavenging compound M30 possesses beneficial effects on major hallmarks of Alzheimer's disease
    • 10.1089/ars.2011.4279
    • Kupershmidt L., Amit T., Bar-Am O., Youdim M. B. H., Weinreb O., The novel multi-target iron chelating-radical scavenging compound M30 possesses beneficial effects on major hallmarks of Alzheimer's disease. Antioxidants & Redox Signaling 2012 17 6 860 877 10.1089/ars.2011.4279
    • (2012) Antioxidants & Redox Signaling , vol.17 , Issue.6 , pp. 860-877
    • Kupershmidt, L.1    Amit, T.2    Bar-Am, O.3    Youdim, M.B.H.4    Weinreb, O.5
  • 93
    • 79952498467 scopus 로고    scopus 로고
    • The potential application of iron chelators for the treatment of neurodegenerative diseases
    • 2-s2.0-79952498467 10.1039/c0mt00087f
    • Hider R. C., Roy S., Ma Y. M., Le Kong X., Preston J., The potential application of iron chelators for the treatment of neurodegenerative diseases. Metallomics 2011 3 3 239 249 2-s2.0-79952498467 10.1039/c0mt00087f
    • (2011) Metallomics , vol.3 , Issue.3 , pp. 239-249
    • Hider, R.C.1    Roy, S.2    Ma, Y.M.3    Le Kong, X.4    Preston, J.5
  • 94
    • 33644660982 scopus 로고    scopus 로고
    • Green tea catechins as brain-permeable, natural iron chelators- antioxidants for the treatment of neurodegenerative disorders
    • DOI 10.1002/mnfr.200500156
    • Mandel S., Amit T., Reznichenko L., Weinreb O., Youdim M. B. H., Green tea catechins as brain-permeable, natural iron chelators-antioxidants for the treatment of neurodegenerative disorders. Molecular Nutrition & Food Research 2006 50 2 229 234 2-s2.0-33644660982 10.1002/mnfr.200500156 (Pubitemid 43325663)
    • (2006) Molecular Nutrition and Food Research , vol.50 , Issue.2 , pp. 229-234
    • Mandel, S.1    Amit, T.2    Reznichenko, L.3    Weinreb, O.4    Youdim, M.B.H.5
  • 95
    • 61349180687 scopus 로고    scopus 로고
    • Getting the iron out: Phlebotomy for Alzheimer's disease?
    • 2-s2.0-61349180687 10.1016/j.mehy.2008.12.029
    • Dwyer B. E., Zacharski L. R., Balestra D. J., Lerner A. J., Perry G., Zhu X., Smith M. A., Getting the iron out: phlebotomy for Alzheimer's disease? Medical Hypotheses 2009 72 5 504 509 2-s2.0-61349180687 10.1016/j.mehy.2008.12. 029
    • (2009) Medical Hypotheses , vol.72 , Issue.5 , pp. 504-509
    • Dwyer, B.E.1    Zacharski, L.R.2    Balestra, D.J.3    Lerner, A.J.4    Perry, G.5    Zhu, X.6    Smith, M.A.7
  • 96
    • 0025726462 scopus 로고
    • Intramuscular desferrioxamine in patients with Alzheimer's disease
    • 2-s2.0-0025726462 10.1016/0140-6736(91)92978-B
    • McLachlan D. R. C., Dalton A. J., Kruck T. P. A., Bell M. Y., Smith W. L., Kalow W., Andrews D. F., Intramuscular desferrioxamine in patients with Alzheimer's disease. The Lancet 1991 337 8753 1304 1308 2-s2.0-0025726462 10.1016/0140-6736(91)92978-B
    • (1991) The Lancet , vol.337 , Issue.8753 , pp. 1304-1308
    • McLachlan, D.R.C.1    Dalton, A.J.2    Kruck, T.P.A.3    Bell, M.Y.4    Smith, W.L.5    Kalow, W.6    Andrews, D.F.7
  • 97
    • 0031058837 scopus 로고    scopus 로고
    • Use of desferrioxamine in the treatment of aceruloplasminemia
    • DOI 10.1002/ana.410410318
    • Miyajima H., Takahashi Y., Kamata T., Shimizu H., Sakai N., Gitlin J. D., Use of desferrioxamine in the treatment of aceruloplasminemia. Annals of Neurology 1997 41 3 404 407 2-s2.0-0031058837 10.1002/ana.410410318 (Pubitemid 27114054)
    • (1997) Annals of Neurology , vol.41 , Issue.3 , pp. 404-407
    • Miyajima, H.1    Takahashi, Y.2    Kamata, T.3    Shimizu, H.4    Sakai, N.5    Gitlin, J.D.6
  • 98
    • 44649108912 scopus 로고    scopus 로고
    • Neuroprotective actions of deferiprone in cultured cortical neurones and SHSY-5Y cells
    • DOI 10.1111/j.1471-4159.2008.05332.x
    • Molina-Holgado F., Gaeta A., Francis P. T., Williams R. J., Hider R. C., Neuroprotective actions of deferiprone in cultured cortical neurones and SHSY-5Y cells. Journal of Neurochemistry 2008 105 6 2466 2476 2-s2.0-44649108912 10.1111/j.1471-4159.2008.05332.x (Pubitemid 351782272)
    • (2008) Journal of Neurochemistry , vol.105 , Issue.6 , pp. 2466-2476
    • Molina-Holgado, F.1    Gaeta, A.2    Francis, P.T.3    Williams, R.J.4    Hider, R.C.5
  • 99
    • 84863247972 scopus 로고    scopus 로고
    • Design and synthesis of fluorinated iron chelators for metabolic study and brain uptake
    • 10.1021/jm201475u
    • Ma Y. M., Roy S., Kong X. L., Chen Y. L., Liu D. Y., Hider R. C., Design and synthesis of fluorinated iron chelators for metabolic study and brain uptake. Journal of Medicinal Chemistry 2012 55 5 2185 2195 10.1021/jm201475u
    • (2012) Journal of Medicinal Chemistry , vol.55 , Issue.5 , pp. 2185-2195
    • Ma, Y.M.1    Roy, S.2    Kong, X.L.3    Chen, Y.L.4    Liu, D.Y.5    Hider, R.C.6
  • 101
    • 48949098573 scopus 로고    scopus 로고
    • Safety, efficacy, and biomarker findings of PBT2 in targeting A β as a modifying therapy for Alzheimer's disease: A phase IIa, double-blind, randomised, placebo-controlled trial
    • 2-s2.0-48949098573 10.1016/S1474-4422(08)70167-4
    • Lannfelt L., Blennow K., Zetterberg H., Batsman S., Ames D., Harrison J., Masters C. L., Targum S., Bush A. I., Murdoch R., Wilson J., Ritchie C. W., Safety, efficacy, and biomarker findings of PBT2 in targeting A β as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial. The Lancet Neurology 2008 7 9 779 786 2-s2.0-48949098573 10.1016/S1474-4422(08)70167-4
    • (2008) The Lancet Neurology , vol.7 , Issue.9 , pp. 779-786
    • Lannfelt, L.1    Blennow, K.2    Zetterberg, H.3    Batsman, S.4    Ames, D.5    Harrison, J.6    Masters, C.L.7    Targum, S.8    Bush, A.I.9    Murdoch, R.10    Wilson, J.11    Ritchie, C.W.12
  • 102
    • 33646490404 scopus 로고    scopus 로고
    • 1,1′-Xylyl bis-1,4,8,11-tetraaza cyclotetradecane: A new potential copper chelator agent for neuroprotection in Alzheimer's disease. Its comparative effects with clioquinol on rat brain copper distribution
    • 2-s2.0-33646490404 10.1016/j.bmcl.2006.03.026
    • Moret V., Laras Y., Pietrancosta N., Garino C., Quélévera G., Rolland A., Mallet B., Norreel J. C., Kraus J. L., 1,1′-Xylyl bis-1,4,8,11-tetraaza cyclotetradecane: a new potential copper chelator agent for neuroprotection in Alzheimer's disease. Its comparative effects with clioquinol on rat brain copper distribution. Bioorganic and Medicinal Chemistry Letters 2006 16 12 3298 3301 2-s2.0-33646490404 10.1016/j.bmcl.2006.03.026
    • (2006) Bioorganic and Medicinal Chemistry Letters , vol.16 , Issue.12 , pp. 3298-3301
    • Moret, V.1    Laras, Y.2    Pietrancosta, N.3    Garino, C.4    Quélévera, G.5    Rolland, A.6    Mallet, B.7    Norreel, J.C.8    Kraus, J.L.9
  • 103
    • 84860838525 scopus 로고    scopus 로고
    • Effects of a tacrine-8-hydroxyquinoline hybrid (IQM-622) on A beta accumulation and cell death: Involvement in hippocampal neuronal loss in Alzheimer's disease
    • 10.1016/j.nbd.2012.03.009
    • Antequera D., Bolos M., Spuch C., Pascual C., Ferrer I., Fernandez-Bachiller M. I., Rodriguez-Franco M. I., Carro E., Effects of a tacrine-8-hydroxyquinoline hybrid (IQM-622) on A beta accumulation and cell death: involvement in hippocampal neuronal loss in Alzheimer's disease. Neurobiology of Disease 2012 46 3 682 691 10.1016/j.nbd.2012.03.009
    • (2012) Neurobiology of Disease , vol.46 , Issue.3 , pp. 682-691
    • Antequera, D.1    Bolos, M.2    Spuch, C.3    Pascual, C.4    Ferrer, I.5    Fernandez-Bachiller, M.I.6    Rodriguez-Franco, M.I.7    Carro, E.8
  • 104
    • 4644238758 scopus 로고    scopus 로고
    • The lipophilic metal chelator DP-109 reduces amyloid pathology in brains of human β-amyloid precursor protein transgenic mice
    • DOI 10.1016/j.neurobiolaging.2004.01.005, PII S0197458004000430
    • Lee J. Y., Friedman J. E., Angel I., Kozak A., Koh J. Y., The lipophilic metal chelator DP-109 reduces amyloid pathology in brains of human β -amyloid precursor protein transgenic mice. Neurobiology of Aging 2004 25 10 1315 1321 2-s2.0-4644238758 10.1016/j.neurobiolaging.2004.01.005 (Pubitemid 39299169)
    • (2004) Neurobiology of Aging , vol.25 , Issue.10 , pp. 1315-1321
    • Lee, J.-Y.1    Friedman, J.E.2    Angel, I.3    Kozak, A.4    Koh, J.-Y.5
  • 105
    • 34447298861 scopus 로고    scopus 로고
    • The lipophilic metal chelators DP-109 and DP-460 are neuroprotective in a transgenic mouse model of amyotrophic lateral sclerosis
    • DOI 10.1111/j.1471-4159.2007.04604.x
    • Petri S., Calingasan N. Y., Alsaied O. A., Wille E., Kiaei M., Friedman J. E., Baranova O., Chavez J. C., Beal M. F., The lipophilic metal chelators DP-109 and DP-460 are neuroprotective in a transgenic mouse model of amyotrophic lateral sclerosis. Journal of Neurochemistry 2007 102 3 991 1000 2-s2.0-34447298861 10.1111/j.1471-4159.2007.04604.x (Pubitemid 47057303)
    • (2007) Journal of Neurochemistry , vol.102 , Issue.3 , pp. 991-1000
    • Petri, S.1    Calingasan, N.Y.2    Alsaied, O.A.3    Wille, E.4    Kiaei, M.5    Friedman, J.E.6    Baranova, O.7    Chavez, J.C.8    Beal, M.F.9
  • 107
    • 12344251715 scopus 로고    scopus 로고
    • Novel D-penicillamine carrying nanoparticles for metal chelation therapy in Alzheimer's and other CNS diseases
    • DOI 10.1016/j.ejpb.2004.07.009, PII S0939641104002097
    • Cui Z., Lockman P. R., Atwood C. S., Hsu C. H., Gupte A., Allen D. D., Mumper R. J., Novel D-penicillamine carrying nanoparticles for metal chelation therapy in Alzheimer's and other CNS diseases. European Journal of Pharmaceutics and Biopharmaceutics 2005 59 2 263 272 2-s2.0-12344251715 10.1016/j.ejpb.2004. 07.009 (Pubitemid 40127583)
    • (2005) European Journal of Pharmaceutics and Biopharmaceutics , vol.59 , Issue.2 , pp. 263-272
    • Cui, Z.1    Lockman, P.R.2    Atwood, C.S.3    Hsu, C.-H.4    Gupte, A.5    Allen, D.D.6    Mumper, R.J.7
  • 109
    • 67349196022 scopus 로고    scopus 로고
    • Organoselenium (Sel-Plex diet) decreases amyloid burden and RNA and DNA oxidative damage in APP/PS1 mice
    • 2-s2.0-67349196022 10.1016/j.freeradbiomed.2009.03.008
    • Lovell M. A., Xiong S., Lyubartseva G., Markesbery W. R., Organoselenium (Sel-Plex diet) decreases amyloid burden and RNA and DNA oxidative damage in APP/PS1 mice. Free Radical Biology and Medicine 2009 46 11 1527 1533 2-s2.0-67349196022 10.1016/j.freeradbiomed.2009.03.008
    • (2009) Free Radical Biology and Medicine , vol.46 , Issue.11 , pp. 1527-1533
    • Lovell, M.A.1    Xiong, S.2    Lyubartseva, G.3    Markesbery, W.R.4
  • 110
    • 80052917464 scopus 로고    scopus 로고
    • Carotenoids and Alzheimer's disease: An insight into therapeutic role of retinoids in animal models
    • 10.1016/j.neuint.2011.04.004
    • Obulesu M., Dowlathabad M. R., Bramhachari P. V., Carotenoids and Alzheimer's disease: an insight into therapeutic role of retinoids in animal models. Neurochemistry International 2011 59 5 535 541 10.1016/j.neuint.2011.04. 004
    • (2011) Neurochemistry International , vol.59 , Issue.5 , pp. 535-541
    • Obulesu, M.1    Dowlathabad, M.R.2    Bramhachari, P.V.3
  • 113
    • 0035503597 scopus 로고    scopus 로고
    • The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse
    • Lim G. P., Chu T., Yang F., Beech W., Frautschy S. A., Cole G. M., The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse. Journal of Neuroscience 2001 21 21 8370 8377 2-s2.0-0035503597 (Pubitemid 33051435)
    • (2001) Journal of Neuroscience , vol.21 , Issue.21 , pp. 8370-8377
    • Lim, G.P.1    Chu, T.2    Yang, F.3    Beech, W.4    Frautschy, S.A.5    Cole, G.M.6
  • 114
    • 38649088871 scopus 로고    scopus 로고
    • Neuroprotective effects of genistein on dopaminergic neurons in the mice model of Parkinson's disease
    • DOI 10.1016/j.neures.2007.10.005, PII S0168010207018160
    • Liu L. X., Chen W. F., Xie J. X., Wong M. S., Neuroprotective effects of genistein on dopaminergic neurons in the mice model of Parkinson's disease. Neuroscience Research 2008 60 2 156 161 2-s2.0-38649088871 10.1016/j.neures. 2007.10.005 (Pubitemid 351173378)
    • (2008) Neuroscience Research , vol.60 , Issue.2 , pp. 156-161
    • Liu, L.-X.1    Chen, W.-F.2    Xie, J.-X.3    Wong, M.-S.4
  • 115
    • 44949125522 scopus 로고    scopus 로고
    • Luteolin reduces IL-6 production in microglia by inhibiting JNK phosphorylation and activation of AP-1
    • DOI 10.1073/pnas.0802865105
    • Jang S., Kelley K. W., Johnson R. W., Luteolin reduces IL-6 production in microglia by inhibiting JNK phosphorylation and activation of AP-1. Proceedings of the National Academy of Sciences of the United States of America 2008 105 21 7534 7539 2-s2.0-44949125522 10.1073/pnas.0802865105 (Pubitemid 351830053)
    • (2008) Proceedings of the National Academy of Sciences of the United States of America , vol.105 , Issue.21 , pp. 7534-7539
    • Jang, S.1    Kelley, K.W.2    Johnson, R.W.3
  • 117
    • 77956224302 scopus 로고    scopus 로고
    • Caffeine exposure and the risk of Parkinson's disease: A systematic review and meta-analysis of observational studiess
    • 2-s2.0-77956224302 10.3233/JAD-2010-091525
    • Costa J., Lunet N., Santos C., Santos J., Vaz-Carneiro A., Caffeine exposure and the risk of Parkinson's disease: a systematic review and meta-analysis of observational studiess. Journal of Alzheimer's Disease 2010 20 1 S221 S238 2-s2.0-77956224302 10.3233/JAD-2010-091525
    • (2010) Journal of Alzheimer's Disease , vol.20 , Issue.1
    • Costa, J.1    Lunet, N.2    Santos, C.3    Santos, J.4    Vaz-Carneiro, A.5
  • 118
    • 41049106214 scopus 로고    scopus 로고
    • Non-motor symptoms in Parkinson's disease
    • DOI 10.1111/j.1468-1331.2008.02056.x
    • Poewe W., Non-motor symptoms in Parkinson's disease. European Journal of Neurology 2008 15 1 14 20 2-s2.0-41049106214 10.1111/j.1468-1331.2008.02056.x (Pubitemid 351421304)
    • (2008) European Journal of Neurology , vol.15 , Issue.SUPPL. 1 , pp. 14-20
    • Poewe, W.1
  • 119
    • 0036776975 scopus 로고    scopus 로고
    • Parkinson's disease: Current and future challenges
    • DOI 10.1016/S0161-813X(02)00098-0, PII S0161813X02000980
    • Langston J. W., Parkinson's disease: current and future challenges. NeuroToxicology 2002 23 4-5 443 450 2-s2.0-0036776975 10.1016/S0161-813X(02) 00098-0 (Pubitemid 36527664)
    • (2002) NeuroToxicology , vol.23 , Issue.4-5 , pp. 443-450
    • Langston, J.W.1
  • 120
    • 0032936755 scopus 로고    scopus 로고
    • Etiology and pathogenesis of Parkinson's disease
    • DOI 10.1146/annurev.neuro.22.1.123
    • Olanow C. W., Tatton W. G., Etiology and pathogenesis of Parkinson's disease. Annual Review of Neuroscience 1999 22 123 144 2-s2.0-0032936755 10.1146/annurev.neuro.22.1.123 (Pubitemid 29144883)
    • (1999) Annual Review of Neuroscience , vol.22 , pp. 123-144
    • Olanow, C.W.1    Tatton, W.G.2
  • 121
    • 5444255434 scopus 로고    scopus 로고
    • Stages in the development of Parkinson's disease-related pathology
    • DOI 10.1007/s00441-004-0956-9
    • Braak H., Ghebremedhin E., Rub U., Bratzke H., Del Tredici K., Stages in the development of Parkinson's disease-related pathology. Cell and Tissue Research 2004 318 1 121 134 2-s2.0-5444255434 10.1007/s00441-004-0956-9 (Pubitemid 39362633)
    • (2004) Cell and Tissue Research , vol.318 , Issue.1 , pp. 121-134
    • Braak, H.1    Ghebremedhin, E.2    Rub, U.3    Bratzke, H.4    Del Tredici, K.5
  • 122
    • 63149090431 scopus 로고    scopus 로고
    • Parkinson's disease: From monogenic forms to genetic susceptibility factors
    • 2-s2.0-63149090431 10.1093/hmg/ddp012
    • Lesage S., Brice A., Parkinson's disease: from monogenic forms to genetic susceptibility factors. Human Molecular Genetics 2009 18 1 R48 R59 2-s2.0-63149090431 10.1093/hmg/ddp012
    • (2009) Human Molecular Genetics , vol.18 , Issue.1
    • Lesage, S.1    Brice, A.2
  • 123
    • 0033556361 scopus 로고    scopus 로고
    • Changing epidemiology of Parkinson's disease in southwestern Finland
    • Kuopio A. M., Marttila R. J., Helenius H., Rinne U. K., Changing epidemiology of Parkinson's disease in southwestern Finland. Neurology 1999 52 2 302 308 2-s2.0-0033556361 10.1212/WNL.52.2.302 (Pubitemid 29059056)
    • (1999) Neurology , vol.52 , Issue.2 , pp. 302-308
    • Kuopio, A.-M.1    Marttila, R.J.2    Helenius, H.3    Rinne, U.K.4
  • 125
    • 33644543761 scopus 로고    scopus 로고
    • Expanding insights of mitochondrial dysfunction in Parkinson's disease
    • DOI 10.1038/nrn1868, PII N1868
    • Abou-Sleiman P. M., Muqit M. M. K., Wood N. W., Expanding insights of mitochondrial dysfunction in Parkinson's disease. Nature Reviews Neuroscience 2006 7 3 207 219 2-s2.0-33644543761 10.1038/nrn1868 (Pubitemid 43292466)
    • (2006) Nature Reviews Neuroscience , vol.7 , Issue.3 , pp. 207-219
    • Abou-Sleiman, P.M.1    Muqit, M.M.K.2    Wood, N.W.3
  • 126
    • 17844406615 scopus 로고    scopus 로고
    • Mechanism of neuroprotective action of the anti-Parkinson drug rasagiline and its derivatives
    • DOI 10.1016/j.brainresrev.2004.12.027, Glial-Neuron Crosstalk in Neuroinflamation, Neurodegeneration and Neuroprotection
    • Mandel S., Weinreb O., Amit T., Youdim M. B. H., Mechanism of neuroprotective action of the anti-Parkinson drug rasagiline and its derivatives. Brain Research Reviews 2005 48 2 379 387 2-s2.0-17844406615 10.1016/j.brainresrev.2004.12.027 (Pubitemid 40590050)
    • (2005) Brain Research Reviews , vol.48 , Issue.2 , pp. 379-387
    • Mandel, S.1    Weinreb, O.2    Amit, T.3    Youdim, M.B.H.4
  • 127
    • 11844262742 scopus 로고    scopus 로고
    • Gene expression profiling of rat midbrain dopamine neurons: Implications for selective vulnerability in parkinsonism
    • DOI 10.1016/j.nbd.2004.10.003, PII S0969996104002360
    • Greene J. G., Dingledine R., Greenamyre J. T., Gene expression profiling of rat midbrain dopamine neurons: implications for selective vulnerability in parkinsonism. Neurobiology of Disease 2005 18 1 19 31 2-s2.0-11844262742 10.1016/j.nbd.2004.10.003 (Pubitemid 40092894)
    • (2005) Neurobiology of Disease , vol.18 , Issue.1 , pp. 19-31
    • Greene, J.G.1    Dingledine, R.2    Greenamyre, J.T.3
  • 128
    • 0031859395 scopus 로고    scopus 로고
    • Mitochondrial DNA transmission of the mitochondrial defect in Parkinson's disease
    • DOI 10.1002/ana.410440207
    • Gu M., Cooper J. M., Taanman J. W., Schapira A. H. V., Mitochondrial DNA transmission of the mitochondrial defect in Parkinson's disease. Annals of Neurology 1998 44 2 177 186 2-s2.0-0031859395 10.1002/ana.410440207 (Pubitemid 28374105)
    • (1998) Annals of Neurology , vol.44 , Issue.2 , pp. 177-186
    • Gu, M.1    Cooper, J.M.2    Taanman, J.W.3    Schapira, A.H.V.4
  • 129
    • 0037378026 scopus 로고    scopus 로고
    • Oxidative stress in Parkinson's disease
    • DOI 10.1002/ana.10483
    • Jenner P., Oxidative stress in Parkinson's disease. Annals of Neurology 2003 53 3 S26 S38 2-s2.0-0037378026 10.1002/ana.10483 (Pubitemid 36368560)
    • (2003) Annals of Neurology , vol.53 , Issue.SUPPL. 3
    • Jenner, P.1
  • 131
  • 132
    • 70449527787 scopus 로고    scopus 로고
    • Neuroprotective effect of ghrelin in the 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine mouse model of Parkinson's disease by blocking microglial activation
    • 2-s2.0-70449527787 10.1007/s12640-009-9037-x
    • Moon M., Kim H. G., Hwang L., Seo J. H., Kim S., Hwang S., Kim S., Lee D., Chung H., Oh M. S., Lee K. T., Park S., Neuroprotective effect of ghrelin in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease by blocking microglial activation. Neurotoxicity Research 2009 15 4 332 347 2-s2.0-70449527787 10.1007/s12640-009-9037-x
    • (2009) Neurotoxicity Research , vol.15 , Issue.4 , pp. 332-347
    • Moon, M.1    Kim, H.G.2    Hwang, L.3    Seo, J.H.4    Kim, S.5    Hwang, S.6    Kim, S.7    Lee, D.8    Chung, H.9    Oh, M.S.10    Lee, K.T.11    Park, S.12
  • 133
    • 34247366072 scopus 로고    scopus 로고
    • Inflammation as a causative factor in the aetiology of Parkinson's disease
    • DOI 10.1038/sj.bjp.0707167, PII 0707167
    • Whitton P. S., Inflammation as a causative factor in the aetiology of Parkinson's disease. British Journal of Pharmacology 2007 150 8 963 976 2-s2.0-34247366072 10.1038/sj.bjp.0707167 (Pubitemid 46628616)
    • (2007) British Journal of Pharmacology , vol.150 , Issue.8 , pp. 963-976
    • Whitton, P.S.1
  • 134
    • 84868646008 scopus 로고    scopus 로고
    • A comprehensive study on long-term injury to nigral dopaminergic neurons following intracerebroventricular injection of lipopolysaccharide in rats
    • 10.1111/jnc.12010
    • Zhou Y., Zhang Y. X., Li J. Q., Lv F. Y., Zhao Y. M., Duan D. Y., Xu Q. Y., A comprehensive study on long-term injury to nigral dopaminergic neurons following intracerebroventricular injection of lipopolysaccharide in rats. Journal of Neurochemistry 2012 123 5 771 780 10.1111/jnc.12010
    • (2012) Journal of Neurochemistry , vol.123 , Issue.5 , pp. 771-780
    • Zhou, Y.1    Zhang, Y.X.2    Li, J.Q.3    Lv, F.Y.4    Zhao, Y.M.5    Duan, D.Y.6    Xu, Q.Y.7
  • 135
    • 66049127133 scopus 로고    scopus 로고
    • Intrastriatal lipopolysaccharide injection induces Parkinsonism in C57/B6 mice
    • 2-s2.0-66049127133 10.1002/jnr.22012
    • Hunter R. L., Cheng B., Choi D. Y., Liu M., Liu S., Cass W. A., Bing G., Intrastriatal lipopolysaccharide injection induces Parkinsonism in C57/B6 mice. Journal of Neuroscience Research 2009 87 8 1913 1921 2-s2.0-66049127133 10.1002/jnr.22012
    • (2009) Journal of Neuroscience Research , vol.87 , Issue.8 , pp. 1913-1921
    • Hunter, R.L.1    Cheng, B.2    Choi, D.Y.3    Liu, M.4    Liu, S.5    Cass, W.A.6    Bing, G.7
  • 137
    • 77951909047 scopus 로고    scopus 로고
    • Environmental toxins and Parkinson's disease: Putative roles of impaired electron transport chain and oxidative stress
    • 2-s2.0-77951909047 10.1177/0748233710362382
    • Arif I. A., Khan H. A., Environmental toxins and Parkinson's disease: putative roles of impaired electron transport chain and oxidative stress. Toxicology and Industrial Health 2010 26 2 121 128 2-s2.0-77951909047 10.1177/0748233710362382
    • (2010) Toxicology and Industrial Health , vol.26 , Issue.2 , pp. 121-128
    • Arif, I.A.1    Khan, H.A.2
  • 138
    • 0038044029 scopus 로고    scopus 로고
    • Critical role for microglial NADPH oxidase in rotenone-induced degeneration of dopaminergic neurons
    • Gao H. M., Liu B., Hong J. S., Critical role for microglial NADPH oxidase in rotenone-induced degeneration of dopaminergic neurons. Journal of Neuroscience 2003 23 15 6181 6187 2-s2.0-0038044029 (Pubitemid 36875618)
    • (2003) Journal of Neuroscience , vol.23 , Issue.15 , pp. 6181-6187
    • Gao, H.-M.1    Liu, B.2    Hong, J.-S.3
  • 139
    • 37649009509 scopus 로고    scopus 로고
    • Induction of microglial reactive oxygen species production by the organochlorinated pesticide dieldrin
    • 2-s2.0-37649009509 10.1016/j.brainres.2007.10.020
    • Mao H., Fang X., Floyd K. M., Polcz J. E., Zhang P., Liu B., Induction of microglial reactive oxygen species production by the organochlorinated pesticide dieldrin. Brain Research 2007 1186 1 267 274 2-s2.0-37649009509 10.1016/j.brainres.2007.10.020
    • (2007) Brain Research , vol.1186 , Issue.1 , pp. 267-274
    • Mao, H.1    Fang, X.2    Floyd, K.M.3    Polcz, J.E.4    Zhang, P.5    Liu, B.6
  • 140
    • 9444284332 scopus 로고    scopus 로고
    • Nanometer size diesel exhaust particles are selectively toxic to dopaminergic neurons: The role of microglia, phagocytosis, and NADPH oxidase
    • DOI 10.1096/fj.04-1945fje
    • Block M. L., Wu X., Pei Z., Li G., Wang T., Qin L., Wilson B., Yang J., Hong J. S., Veronesi B., Nanometer size diesel exhaust particles are selectively toxic to dopaminergic neurons: the role of microglia, phagocytosis, and NADPH oxidase. The FASEB Journal 2004 18 13 1618 1620 2-s2.0-9444284332 10.1096/fj.04-1945fje (Pubitemid 39561652)
    • (2004) FASEB Journal , vol.18 , Issue.13 , pp. 1618-1620
    • Block, M.L.1    Wu, X.2    Pei, Z.3    Li, G.4    Wang, T.5    Qin, L.6    Wilson, B.7    Yang, J.8    Hong, J.S.9    Veronesi, B.10
  • 141
    • 52649126841 scopus 로고    scopus 로고
    • Synergistic microglial reactive oxygen species generation induced by pesticides lindane and dieldrin
    • 2-s2.0-52649126841 10.1097/WNR.0b013e32830b3677
    • Mao H., Liu B., Synergistic microglial reactive oxygen species generation induced by pesticides lindane and dieldrin. NeuroReport 2008 19 13 1317 1320 2-s2.0-52649126841 10.1097/WNR.0b013e32830b3677
    • (2008) NeuroReport , vol.19 , Issue.13 , pp. 1317-1320
    • Mao, H.1    Liu, B.2
  • 142
    • 35648932406 scopus 로고    scopus 로고
    • Reactive oxygen species generation by the ethylene-bis-dithiocarbamate (EBDC) fungicide mancozeb and its contribution to neuronal toxicity in mesencephalic cells
    • DOI 10.1016/j.neuro.2007.04.008, PII S0161813X07000721
    • Domico L. M., Cooper K. R., Bernard L. P., Zeevalk G. D., Reactive oxygen species generation by the ethylene-bis-dithiocarbamate (EBDC) fungicide mancozeb and its contribution to neuronal toxicity in mesencephalic cells. NeuroToxicology 2007 28 6 1079 1091 2-s2.0-35648932406 10.1016/j.neuro.2007.04. 008 (Pubitemid 350026582)
    • (2007) NeuroToxicology , vol.28 , Issue.6 , pp. 1079-1091
    • Domico, L.M.1    Cooper, K.R.2    Bernard, L.P.3    Zeevalk, G.D.4
  • 143
    • 84861791982 scopus 로고    scopus 로고
    • Brief mitochondrial inhibition causes lasting changes in motor behavior and corticostriatal synaptic physiology in the Fischer 344 rat
    • 10.1016/j.neuroscience.2012.04.060
    • Akopian G., Crawford C., Petzinger G., Jakowec M. W., Walsh J. P., Brief mitochondrial inhibition causes lasting changes in motor behavior and corticostriatal synaptic physiology in the Fischer 344 rat. Neuroscience 2012 215 149 159 10.1016/j.neuroscience.2012.04.060
    • (2012) Neuroscience , vol.215 , pp. 149-159
    • Akopian, G.1    Crawford, C.2    Petzinger, G.3    Jakowec, M.W.4    Walsh, J.P.5
  • 144
    • 29144468251 scopus 로고    scopus 로고
    • 3-Nitropropionic acid: A mitochondrial toxin to uncover physiopathological mechanisms underlying striatal degeneration in Huntington's disease
    • DOI 10.1111/j.1471-4159.2005.03515.x
    • Brouillet E., Jacquard C., Bizat N., Blum D., 3-Nitropropionic acid: a mitochondrial toxin to uncover physiopathological mechanisms underlying striatal degeneration in Huntington's disease. Journal of Neurochemistry 2005 95 6 1521 1540 2-s2.0-29144468251 10.1111/j.1471-4159.2005.03515.x (Pubitemid 41804051)
    • (2005) Journal of Neurochemistry , vol.95 , Issue.6 , pp. 1521-1540
    • Brouillet, E.1    Jacquard, C.2    Bizat, N.3    Blum, D.4
  • 145
    • 84857500330 scopus 로고    scopus 로고
    • Traumatic brain injury and trichloroethylene exposure interact and produce functional, histological, and mitochondrial deficits
    • 10.1016/j.expneurol.2011.12.012
    • Sauerbeck A., Hunter R., Bing G. Y., Sullivan P. G., Traumatic brain injury and trichloroethylene exposure interact and produce functional, histological, and mitochondrial deficits. Experimental Neurology 2012 234 1 85 94 10.1016/j.expneurol.2011.12.012
    • (2012) Experimental Neurology , vol.234 , Issue.1 , pp. 85-94
    • Sauerbeck, A.1    Hunter, R.2    Bing, G.Y.3    Sullivan, P.G.4
  • 147
    • 0033037034 scopus 로고    scopus 로고
    • Occupational exposure to manganese, copper, lead, iron, mercury and zinc and the risk of Parkinson's disease
    • Gorell J. M., Johnson C. C., Rybicki B. A., Peterson E. L., Kortsha G. X., Brown G. G., Richardson R. J., Occupational exposure to manganese, copper, lead, iron, mercury and zinc and the risk of Parkinson's disease. NeuroToxicology 1999 20 2-3 239 248 2-s2.0-0033037034 (Pubitemid 29268568)
    • (1999) NeuroToxicology , vol.20 , Issue.2-3 , pp. 239-248
    • Gorell, J.M.1    Johnson, C.C.2    Rybicki, B.A.3    Peterson, E.L.4    Kortsha, G.X.5    Brown, G.G.6    Richardson, R.J.7
  • 150
    • 79955786502 scopus 로고    scopus 로고
    • Air pollution is associated with brainstem auditory nuclei pathology and delayed brainstem auditory evoked potentials
    • 2-s2.0-79955786502 10.1016/j.ijdevneu.2011.03.007
    • Calderon-Garciduenas L., D'Angiulli A., Kulesza R. J., Air pollution is associated with brainstem auditory nuclei pathology and delayed brainstem auditory evoked potentials. International Journal of Developmental Neuroscience 2011 29 4 365 375 2-s2.0-79955786502 10.1016/j.ijdevneu.2011.03.007
    • (2011) International Journal of Developmental Neuroscience , vol.29 , Issue.4 , pp. 365-375
    • Calderon-Garciduenas, L.1    D'Angiulli, A.2    Kulesza, R.J.3
  • 151
    • 3142514201 scopus 로고    scopus 로고
    • Protein aggregation and neurodegenerative disease
    • DOI 10.1038/nm1066
    • Ross C. A., Poirier M. A., Protein aggregation and neurodegenerative disease. Nature Medicine 2004 10 7 S10 S17 2-s2.0-3142514201 10.1038/nm1066 (Pubitemid 38901862)
    • (2004) Nature Medicine , vol.10 , Issue.SUPPL.
    • Ross, C.A.1    Poirier, M.A.2
  • 152
    • 0025276828 scopus 로고
    • Cognitive impairment in Parkinson's disease: Amyloid plagues, neurofibrillary tangles, and neuropil threads in the cerebral cortex
    • DOI 10.1007/BF02251245
    • Braak H., Braak E., Cognitive impairment in Parkinson's disease: amyloid plagues, neurofibrillary tangles, and neuropil threads in the cerebral cortex. Journal of Neural Transmission. Parkinson's Disease and Dementia Section 1990 2 1 45 57 2-s2.0-0025276828 10.1007/BF02251245 (Pubitemid 20215381)
    • (1990) Journal of Neural Transmission - Parkinson's Disease and Dementia Section , vol.2 , Issue.1 , pp. 45-57
    • Braak, H.1    Braak, E.2
  • 154
    • 36949032824 scopus 로고    scopus 로고
    • Microglial activation mediates neurodegeneration related to oligodendroglial α -synucleinopathy: Implications for multiple system atrophy
    • 2-s2.0-36949032824 10.1002/mds.21671
    • Stefanova N., Reindl M., Neumann M., Kahle P. J., Poewe W., Wenning G. K., Microglial activation mediates neurodegeneration related to oligodendroglial α -synucleinopathy: implications for multiple system atrophy. Movement Disorders 2007 22 15 2196 2203 2-s2.0-36949032824 10.1002/mds.21671
    • (2007) Movement Disorders , vol.22 , Issue.15 , pp. 2196-2203
    • Stefanova, N.1    Reindl, M.2    Neumann, M.3    Kahle, P.J.4    Poewe, W.5    Wenning, G.K.6
  • 155
    • 20144389524 scopus 로고    scopus 로고
    • Aggregated α-synuclein activates microglia: A process leading to disease progression in Parkinson's disease
    • DOI 10.1096/fj.04-2751com
    • Zhang W., Wang T., Pei Z., Miller D. S., Wu X., Block M. L., Wilson B., Zhang W., Zhou Y., Hong J. S., Zhang J., Aggregated α -synuclein activates microglia: a process leading to disease progression in Parkinson's disease. The FASEB Journal 2005 19 6 533 542 2-s2.0-20144389524 10.1096/fj.04-2751com (Pubitemid 40471244)
    • (2005) FASEB Journal , vol.19 , Issue.6 , pp. 533-542
    • Zhang, W.1    Wang, T.2    Pei, Z.3    Miller, D.S.4    Wu, X.5    Block, M.L.6    Wilson, B.7    Zhang, W.8    Zhou, Y.9    Hong, J.-S.10    Zhang, J.11
  • 156
    • 50549085408 scopus 로고    scopus 로고
    • Neuroinflammation and oxidation/nitration of α -synuclein linked to dopaminergic neurodegeneration
    • 2-s2.0-50549085408 10.1523/JNEUROSCI.0143-07.2008
    • Gao H. M., Kotzbauer P. T., Uryu K., Leight S., Trojanowski J. Q., Lee V. M. Y., Neuroinflammation and oxidation/nitration of α -synuclein linked to dopaminergic neurodegeneration. Journal of Neuroscience 2008 28 30 7687 7698 2-s2.0-50549085408 10.1523/JNEUROSCI.0143-07.2008
    • (2008) Journal of Neuroscience , vol.28 , Issue.30 , pp. 7687-7698
    • Gao, H.M.1    Kotzbauer, P.T.2    Uryu, K.3    Leight, S.4    Trojanowski, J.Q.5    Lee, V.M.Y.6
  • 157
    • 0035030335 scopus 로고    scopus 로고
    • Changes in the immune system in depression and dementia: Causal or co-incidental effects?
    • DOI 10.1016/S0736-5748(01)00014-4, PII S0736574801000144
    • Leonard B. E., Changes in the immune system in depression and dementia: causal or co-incidental effects? International Journal of Developmental Neuroscience 2001 19 3 305 312 2-s2.0-0035030335 10.1016/S0736-5748(01)00014-4 (Pubitemid 32405350)
    • (2001) International Journal of Developmental Neuroscience , vol.19 , Issue.3 , pp. 305-312
    • Leonard, B.E.1
  • 158
    • 60349132064 scopus 로고    scopus 로고
    • The role of neuroimmunomodulation in Alzheimer's disease
    • 2-s2.0-60349132064 10.1111/j.1749-6632.2008.03972.x
    • Maccioni R. B., Rojo L. E., Fernández J. A., Kuljis R. O., The role of neuroimmunomodulation in Alzheimer's disease. Annals of the New York Academy of Sciences 2009 1153 240 246 2-s2.0-60349132064 10.1111/j.1749-6632. 2008.03972.x
    • (2009) Annals of the New York Academy of Sciences , vol.1153 , pp. 240-246
    • Maccioni, R.B.1    Rojo, L.E.2    Fernández, J.A.3    Kuljis, R.O.4
  • 159
    • 0028971093 scopus 로고
    • Beta-amyloid-induced toxicity in rat hippocampal cells: In vitro evidence for the involvement of free radicals
    • DOI 10.1016/0361-9230(95)02034-X
    • Manelli A. M., Puttfarcken P. S., β -Amyloid-induced toxicity in rat hippocampal cells: in vitro evidence for the involvement of free radicals. Brain Research Bulletin 1995 38 6 569 576 2-s2.0-0028971093 10.1016/0361- 9230(95)02034-X (Pubitemid 3007073)
    • (1995) Brain Research Bulletin , vol.38 , Issue.6 , pp. 569-576
    • Manelli, A.M.1    Puttfarcken, P.S.2
  • 160
    • 84869176950 scopus 로고    scopus 로고
    • β-Amyloid induced effects on cholinergic, serotonergic, and dopaminergic neurons is differentially counteracted by anti-inflammatory drugs
    • Hochstrasser T., Hohsfield L. A., Sperner-Unterweger B., Humpel C., β -Amyloid induced effects on cholinergic, serotonergic, and dopaminergic neurons is differentially counteracted by anti-inflammatory drugs. Journal of Neuroscience Research 2013 91 1 83 94
    • (2013) Journal of Neuroscience Research , vol.91 , Issue.1 , pp. 83-94
    • Hochstrasser, T.1    Hohsfield, L.A.2    Sperner-Unterweger, B.3    Humpel, C.4
  • 161
    • 79960341281 scopus 로고    scopus 로고
    • CSF α -synuclein, tau, and amyloid β in Parkinson's disease
    • 2-s2.0-79960353168 10.1016/S1474-4422(11)70130-2
    • Shi M., Zhang J., CSF α -synuclein, tau, and amyloid β in Parkinson's disease. The Lancet Neurology 2011 10 8 681 2-s2.0-79960353168 10.1016/S1474-4422(11)70130-2
    • (2011) The Lancet Neurology , vol.10 , Issue.8 , pp. 681
    • Shi, M.1    Zhang, J.2
  • 162
    • 80054905220 scopus 로고    scopus 로고
    • A role for microglia in synaptic plasticity?
    • 10.4161/cib.4.2.14506
    • Tremblay M. E., Majewska A. K., A role for microglia in synaptic plasticity? Communicative & Integrative Biology 2011 4 2 220 222 10.4161/cib.4.2.14506
    • (2011) Communicative & Integrative Biology , vol.4 , Issue.2 , pp. 220-222
    • Tremblay, M.E.1    Majewska, A.K.2
  • 163
    • 60149098421 scopus 로고    scopus 로고
    • Debris clearance by microglia: An essential link between degeneration and regeneration
    • 2-s2.0-60149098421 10.1093/brain/awn109
    • Neumann H., Kotter M. R., Franklin R. J. M., Debris clearance by microglia: an essential link between degeneration and regeneration. Brain 2009 132 2 288 295 2-s2.0-60149098421 10.1093/brain/awn109
    • (2009) Brain , vol.132 , Issue.2 , pp. 288-295
    • Neumann, H.1    Kotter, M.R.2    Franklin, R.J.M.3
  • 164
    • 79958281908 scopus 로고    scopus 로고
    • The promise of anti-inflammatory therapies for CNS injuries and diseases
    • 2-s2.0-79958281908 10.1586/ern.11.64
    • Rivest S., The promise of anti-inflammatory therapies for CNS injuries and diseases. Expert Review of Neurotherapeutics 2011 11 6 783 786 2-s2.0-79958281908 10.1586/ern.11.64
    • (2011) Expert Review of Neurotherapeutics , vol.11 , Issue.6 , pp. 783-786
    • Rivest, S.1
  • 165
    • 33845768784 scopus 로고    scopus 로고
    • Microglia-mediated neurotoxicity: Uncovering the molecular mechanisms
    • DOI 10.1038/nrn2038, PII NRN2038
    • Block M. L., Zecca L., Hong J. S., Microglia-mediated neurotoxicity: uncovering the molecular mechanisms. Nature Reviews Neuroscience 2007 8 1 57 69 2-s2.0-33845768784 10.1038/nrn2038 (Pubitemid 46011999)
    • (2007) Nature Reviews Neuroscience , vol.8 , Issue.1 , pp. 57-69
    • Block, M.L.1    Zecca, L.2    Hong, J.-S.3
  • 166
    • 0025220976 scopus 로고
    • Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain
    • 2-s2.0-0025220976 10.1016/0306-4522(90)90229-W
    • Lawson L. J., Perry V. H., Dri P., Gordon S., Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain. Neuroscience 1990 39 1 151 170 2-s2.0-0025220976 10.1016/0306-4522(90)90229-W
    • (1990) Neuroscience , vol.39 , Issue.1 , pp. 151-170
    • Lawson, L.J.1    Perry, V.H.2    Dri, P.3    Gordon, S.4
  • 167
    • 0035105538 scopus 로고    scopus 로고
    • Local distribution of microglia in the normal adult human central nervous system differs by up to one order of magnitude
    • Mittelbronn M., Dietz K., Schluesener H. J., Meyermann R., Local distribution of microglia in the normal adult human central nervous system differs by up to one order of magnitude. Acta Neuropathologica 2001 101 3 249 255 2-s2.0-0035105538 (Pubitemid 32219759)
    • (2001) Acta Neuropathologica , vol.101 , Issue.3 , pp. 249-255
    • Mittelbronn, M.1    Dietz, K.2    Schluesener, H.J.3    Meyermann, R.4
  • 168
    • 84856181466 scopus 로고    scopus 로고
    • Dysregulated neuronal-microglial cross-talk during aging, stress and inflammation
    • 2-s2.0-78650556025 10.1016/j.expneurol.2010.11.014
    • Jurgens H. A., Johnson R. W., Dysregulated neuronal-microglial cross-talk during aging, stress and inflammation. Experimental Neurology 2012 233 1 40 48 2-s2.0-78650556025 10.1016/j.expneurol.2010.11.014
    • (2012) Experimental Neurology , vol.233 , Issue.1 , pp. 40-48
    • Jurgens, H.A.1    Johnson, R.W.2
  • 169
    • 0031960498 scopus 로고    scopus 로고
    • Microglial expression of MHC class II increases in normal aging of nonhuman primates
    • DOI 10.1016/S0197-4580(97)00168-1, PII S0197458097001681
    • Sheffield L. G., Berman N. E. J., Microglial expression of MHC class II increases in normal aging of nonhuman primates. Neurobiology of Aging 1998 19 1 47 55 2-s2.0-0031960498 10.1016/S0197-4580(97)00168-1 (Pubitemid 28167795)
    • (1998) Neurobiology of Aging , vol.19 , Issue.1 , pp. 47-55
    • Sheffield, L.G.1    Berman, N.E.J.2
  • 170
    • 0027351431 scopus 로고
    • Cytotoxicity of microglia
    • 2-s2.0-0027351431 10.1002/glia.440070117
    • Banati R. B., Gehrmann J., Schubert P., Kreutzberg G. W., Cytotoxicity of microglia. Glia 1993 7 1 111 118 2-s2.0-0027351431 10.1002/glia.440070117
    • (1993) Glia , vol.7 , Issue.1 , pp. 111-118
    • Banati, R.B.1    Gehrmann, J.2    Schubert, P.3    Kreutzberg, G.W.4
  • 171
    • 0029076362 scopus 로고
    • Microglia: Intrinsic immuneffector cell of the brain
    • 2-s2.0-0029076362 10.1016/0165-0173(94)00015-H
    • Gehrmann J., Matsumoto Y., Kreutzberg G. W., Microglia: intrinsic immuneffector cell of the brain. Brain Research Reviews 1995 20 3 269 287 2-s2.0-0029076362 10.1016/0165-0173(94)00015-H
    • (1995) Brain Research Reviews , vol.20 , Issue.3 , pp. 269-287
    • Gehrmann, J.1    Matsumoto, Y.2    Kreutzberg, G.W.3
  • 172
    • 0028800715 scopus 로고
    • Cytokines and the nervous system I: Expression and recognition
    • 2-s2.0-0028800715 10.1016/0166-2236(95)93881-W
    • Hopkins S. J., Rothwell N. J., Cytokines and the nervous system I: expression and recognition. Trends in Neurosciences 1995 18 2 83 88 2-s2.0-0028800715 10.1016/0166-2236(95)93881-W
    • (1995) Trends in Neurosciences , vol.18 , Issue.2 , pp. 83-88
    • Hopkins, S.J.1    Rothwell, N.J.2
  • 173
    • 77950858637 scopus 로고    scopus 로고
    • Microglia in neurodegenerative disease
    • 2-s2.0-77950858637 10.1038/nrneurol.2010.17
    • Perry V. H., Nicoll J. A. R., Holmes C., Microglia in neurodegenerative disease. Nature Reviews Neurology 2010 6 4 193 201 2-s2.0-77950858637 10.1038/nrneurol.2010.17
    • (2010) Nature Reviews Neurology , vol.6 , Issue.4 , pp. 193-201
    • Perry, V.H.1    Nicoll, J.A.R.2    Holmes, C.3
  • 174
    • 17044432238 scopus 로고    scopus 로고
    • Matrix metalloproteinase-3: A novel signaling proteinase from apoptotic neuronal cells that activates microglia
    • 2-s2.0-17044432238 10.1523/JNEUROSCI.4346-04.2005
    • Kim Y. S., Kim S. S., Cho J. J., Choi D. H., Hwang O., Shin D. H., Chun H. S., Beal M. F., Joh T. H., Matrix metalloproteinase-3: a novel signaling proteinase from apoptotic neuronal cells that activates microglia. Journal of Neuroscience 2005 25 14 3701 3711 2-s2.0-17044432238 10.1523/JNEUROSCI.4346-04. 2005
    • (2005) Journal of Neuroscience , vol.25 , Issue.14 , pp. 3701-3711
    • Kim, Y.S.1    Kim, S.S.2    Cho, J.J.3    Choi, D.H.4    Hwang, O.5    Shin, D.H.6    Chun, H.S.7    Beal, M.F.8    Joh, T.H.9
  • 175
    • 33748447845 scopus 로고    scopus 로고
    • Microglia, major player in the brain inflammation: Their roles in the pathogenesis of Parkinson's disease
    • 2-s2.0-33748447845 10.1038/emm.2006.40
    • Kim Y. S., Joh T. H., Microglia, major player in the brain inflammation: their roles in the pathogenesis of Parkinson's disease. Experimental and Molecular Medicine 2006 38 4 333 347 2-s2.0-33748447845 10.1038/emm.2006.40
    • (2006) Experimental and Molecular Medicine , vol.38 , Issue.4 , pp. 333-347
    • Kim, Y.S.1    Joh, T.H.2
  • 177
    • 30744455267 scopus 로고    scopus 로고
    • Microglia proliferation is regulated by hydrogen peroxide from NADPH oxidase
    • Mander P. K., Jekabsone A., Brown G. C., Microglia proliferation is regulated by hydrogen peroxide from NADPH oxidase. Journal of Immunology 2006 176 2 1046 1052 2-s2.0-30744455267 (Pubitemid 43099705)
    • (2006) Journal of Immunology , vol.176 , Issue.2 , pp. 1046-1052
    • Mander, P.K.1    Jekabsone, A.2    Brown, G.C.3
  • 178
    • 77649213747 scopus 로고    scopus 로고
    • Interleukin-4-induced oxidative stress via microglial NADPH oxidase contributes to the death of hippocampal neurons in vivo
    • 2-s2.0-77649213747 10.2174/1874609810801030192
    • Park K. W., Baik H. H., Jin B. K., Interleukin-4-induced oxidative stress via microglial NADPH oxidase contributes to the death of hippocampal neurons in vivo. Current Aging Science 2008 1 3 192 201 2-s2.0-77649213747 10.2174/1874609810801030192
    • (2008) Current Aging Science , vol.1 , Issue.3 , pp. 192-201
    • Park, K.W.1    Baik, H.H.2    Jin, B.K.3
  • 179
    • 70449723396 scopus 로고    scopus 로고
    • IL-13-induced oxidative stress via microglial NADPH oxidase contributes to death of hippocampal neurons in vivo
    • 2-s2.0-70449723396 10.4049/jimmunol.0803392
    • Park K. W., Baik H. H., Jin B. K., IL-13-induced oxidative stress via microglial NADPH oxidase contributes to death of hippocampal neurons in vivo. Journal of Immunology 2009 183 7 4666 4674 2-s2.0-70449723396 10.4049/jimmunol.0803392
    • (2009) Journal of Immunology , vol.183 , Issue.7 , pp. 4666-4674
    • Park, K.W.1    Baik, H.H.2    Jin, B.K.3
  • 180
    • 33751192706 scopus 로고    scopus 로고
    • The microglial NADPH oxidase complex as a source of oxidative stress in Alzheimer's disease
    • DOI 10.1186/1742-2094-3-30
    • Wilkinson B. L., Landreth G. E., The microglial NADPH oxidase complex as a source of oxidative stress in Alzheimer's disease. Journal of Neuroinflammation 2006 3, article 30 2-s2.0-33751192706 10.1186/1742-2094-3-30 (Pubitemid 44774182)
    • (2006) Journal of Neuroinflammation , vol.3 , pp. 30
    • Wilkinson, B.L.1    Landreth, G.E.2
  • 181
    • 5444255433 scopus 로고    scopus 로고
    • Neurotoxicant-induced animal models of Parkinson's disease: Understanding the role of rotenone, maneb and paraquat in neurodegeneration
    • DOI 10.1007/s00441-004-0937-z
    • Uversky V. N., Neurotoxicant-induced animal models of Parkinson's disease: understanding the role of rotenone, maneb and paraquat in neurodegeneration. Cell and Tissue Research 2004 318 1 225 241 2-s2.0-5444255433 10.1007/s00441-004-0937-z (Pubitemid 39362642)
    • (2004) Cell and Tissue Research , vol.318 , Issue.1 , pp. 225-241
    • Uversky, V.N.1
  • 182
    • 0032983334 scopus 로고    scopus 로고
    • - forming NADPH oxidase in microglia, monocytes, and neutrophils. A possible inflammatory mechanism of neuronal damage in Alzheimer's disease
    • DOI 10.1074/jbc.274.22.15493
    • Della Bianca V., Dusi S., Bianchini E., Dal Pra I., Rossi F., β -Amyloid activates the O2·̄ forming NADPH oxidase in microglia, monocytes, and neutrophils. A possible inflammatory mechanism of neuronal damage in Alzheimer's disease. Journal of Biological Chemistry 1999 274 22 15493 15499 2-s2.0-0032983334 10.1074/jbc.274.22.15493 (Pubitemid 29254916)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.22 , pp. 15493-15499
    • Della Bianca, V.1    Dusi, S.2    Bianchini, E.3    Dal Pra, I.4    Rossi, F.5
  • 183
    • 0032524692 scopus 로고    scopus 로고
    • Measurement and characterization of superoxide generation in microglial cells: Evidence for an NADPH oxidase-dependent pathway
    • DOI 10.1006/abbi.1998.0658
    • Sankarapandi S., Zweier J. L., Mukherjee G., Quinn M. T., Huso D. L., Measurement and characterization of superoxide generation in microglial cells: evidence for an NADPH oxidase-dependent pathway. Archives of Biochemistry and Biophysics 1998 353 2 312 321 2-s2.0-0032524692 10.1006/abbi.1998.0658 (Pubitemid 28373015)
    • (1998) Archives of Biochemistry and Biophysics , vol.353 , Issue.2 , pp. 312-321
    • Sankarapandi, S.1    Zweier, J.L.2    Mukherjee, G.3    Quinn, M.T.4    Huso, D.L.5
  • 184
    • 77957086962 scopus 로고    scopus 로고
    • Role of microglia in neurotrauma
    • 2-s2.0-77957086962 10.1016/j.nurt.2010.07.002
    • Loane D. J., Byrnes K. R., Role of microglia in neurotrauma. Neurotherapeutics 2010 7 4 366 377 2-s2.0-77957086962 10.1016/j.nurt.2010.07.002
    • (2010) Neurotherapeutics , vol.7 , Issue.4 , pp. 366-377
    • Loane, D.J.1    Byrnes, K.R.2
  • 186
    • 33846308531 scopus 로고    scopus 로고
    • Microglial activation as a priming event leading to paraquat-induced dopaminergic cell degeneration
    • DOI 10.1016/j.nbd.2006.10.008, PII S0969996106002579
    • Purisai M. G., McCormack A. L., Cumine S., Li J., Isla M. Z., Di Monte D. A., Microglial activation as a priming event leading to paraquat-induced dopaminergic cell degeneration. Neurobiology of Disease 2007 25 2 392 400 2-s2.0-33846308531 10.1016/j.nbd.2006.10.008 (Pubitemid 46124019)
    • (2007) Neurobiology of Disease , vol.25 , Issue.2 , pp. 392-400
    • Purisai, M.G.1    McCormack, A.L.2    Cumine, S.3    Li, J.4    Isla, M.Z.5    Di Monte, D.A.6
  • 187
    • 84861188146 scopus 로고    scopus 로고
    • Interferon- γ plays a role in paraquat-induced neurodegeneration involving oxidative and proinflammatory pathways
    • 2-s2.0-79953754893 10.1016/j.neurobiolaging.2011.02.016
    • Mangano E. N., Litteljohn D., So R., Nelson E., Peters S., Bethune C., Bobyn J., Hayley S., Interferon- γ plays a role in paraquat-induced neurodegeneration involving oxidative and proinflammatory pathways. Neurobiology of Aging 2012 33 7 1411 1426 2-s2.0-79953754893 10.1016/j.neurobiolaging.2011. 02.016
    • (2012) Neurobiology of Aging , vol.33 , Issue.7 , pp. 1411-1426
    • Mangano, E.N.1    Litteljohn, D.2    So, R.3    Nelson, E.4    Peters, S.5    Bethune, C.6    Bobyn, J.7    Hayley, S.8
  • 188
    • 0023882918 scopus 로고
    • Chronic exposure to the fungicide maneb may produce symptoms and signs of CNS manganese intoxication
    • 2-s2.0-0023882918 10.1212/WNL.38.4.550
    • Ferraz H. B., Bertolucci P. H. F., Pereira J. S., Lima J. G. C., Andrade L. A. F., Chronic exposure to the fungicide maneb may produce symptoms and signs of CNS manganese intoxication. Neurology 1988 38 4 550 553 2-s2.0-0023882918 10.1212/WNL.38.4.550
    • (1988) Neurology , vol.38 , Issue.4 , pp. 550-553
    • Ferraz, H.B.1    Bertolucci, P.H.F.2    Pereira, J.S.3    Lima, J.G.C.4    Andrade, L.A.F.5
  • 189
    • 0031843721 scopus 로고    scopus 로고
    • The risk of Parkinson's disease with exposure to pesticides, farming, well water, and rural living
    • Gorell J. M., Johnson C. C., Rybicki B. A., Peterson E. L., Richardson R. J., The risk of Parkinson's disease with exposure to pesticides, farming, well water, and rural living. Neurology 1998 50 5 1346 1350 2-s2.0-0031843721 10.1212/WNL.50.5.1346 (Pubitemid 28240350)
    • (1998) Neurology , vol.50 , Issue.5 , pp. 1346-1350
    • Gorell, J.M.1    Johnson, C.C.2    Rybicki, B.A.3    Peterson, E.L.4    Richardson, R.J.5
  • 190
    • 0030878320 scopus 로고    scopus 로고
    • Environmental risk factors and Parkinson's disease: A case-control study in Taiwan
    • 2-s2.0-0030878320 10.1212/WNL.48.6.1583
    • Liou H. H., Tsai M. C., Chen C. J., Jeng J. S., Chang Y. C., Chen S. Y., Chen R. C., Environmental risk factors and Parkinson's disease: a case-control study in Taiwan. Neurology 1997 48 6 1583 1588 2-s2.0-0030878320 10.1212/WNL.48.6.1583
    • (1997) Neurology , vol.48 , Issue.6 , pp. 1583-1588
    • Liou, H.H.1    Tsai, M.C.2    Chen, C.J.3    Jeng, J.S.4    Chang, Y.C.5    Chen, S.Y.6    Chen, R.C.7
  • 191
    • 34250783638 scopus 로고    scopus 로고
    • Iron in Chronic Brain Disorders: Imaging and Neurotherapeutic Implications
    • DOI 10.1016/j.nurt.2007.05.006, PII S1933721307000906
    • Stankiewicz J., Panter S. S., Neema M., Arora A., Batt C. E., Bakshi R., Iron in chronic brain disorders: imaging and neurotherapeutic implications. Neurotherapeutics 2007 4 3 371 386 2-s2.0-34250783638 10.1016/j.nurt.2007.05.006 (Pubitemid 46962416)
    • (2007) Neurotherapeutics , vol.4 , Issue.3 , pp. 371-386
    • Stankiewicz, J.1    Panter, S.S.2    Neema, M.3    Arora, A.4    Batt, C.E.5    Bakshi, R.6
  • 192
    • 33845387875 scopus 로고    scopus 로고
    • Iron accumulation in the striatum predicts aging-related decline in motor function in rhesus monkeys
    • DOI 10.1016/j.neurobiolaging.2005.12.010, PII S0197458005004549
    • Cass W. A., Grondin R., Andersen A. H., Zhang Z., Hardy P. A., Hussey-Andersen L. K., Rayens W. S., Gerhardt G. A., Gash D. M., Iron accumulation in the striatum predicts aging-related decline in motor function in rhesus monkeys. Neurobiology of Aging 2007 28 2 258 271 2-s2.0-33845387875 10.1016/j.neurobiolaging.2005.12.010 (Pubitemid 44894635)
    • (2007) Neurobiology of Aging , vol.28 , Issue.2 , pp. 258-271
    • Cass, W.A.1    Grondin, R.2    Andersen, A.H.3    Zhang, Z.4    Hardy, P.A.5    Hussey-Andersen, L.K.6    Rayens, W.S.7    Gerhardt, G.A.8    Gash, D.M.9
  • 194
    • 84864531764 scopus 로고    scopus 로고
    • Copper, zinc and iron in neurodegenerative diseases (Alzheimer's, Parkinson's and prion diseases)
    • 10.1016/j.ccr.2012.03.013
    • Kozlowski H., Luczkowski M., Remelli M., Valensin D., Copper, zinc and iron in neurodegenerative diseases (Alzheimer's, Parkinson's and prion diseases). Coordination Chemistry Reviews 2012 256 2129 2141 10.1016/j.ccr.2012.03.013
    • (2012) Coordination Chemistry Reviews , vol.256 , pp. 2129-2141
    • Kozlowski, H.1    Luczkowski, M.2    Remelli, M.3    Valensin, D.4
  • 195
    • 33644658492 scopus 로고    scopus 로고
    • Whole genome expression profiling of the medial and lateral substantia nigra in Parkinson's disease
    • DOI 10.1007/s10048-005-0020-2
    • Moran L. B., Duke D. C., Deprez M., Dexter D. T., Pearce R. K. B., Graeber M. B., Whole genome expression profiling of the medial and lateral substantia nigra in Parkinson's disease. Neurogenetics 2006 7 1 1 11 2-s2.0-33644658492 10.1007/s10048-005-0020-2 (Pubitemid 43327678)
    • (2006) Neurogenetics , vol.7 , Issue.1 , pp. 1-11
    • Moran, L.B.1    Duke, D.C.2    Deprez, M.3    Dexter, D.T.4    Pearce, R.K.B.5    Graeber, M.B.6
  • 196
    • 23044502947 scopus 로고    scopus 로고
    • Transcriptional analysis of multiple brain regions in Parkinson's disease supports the involvement of specific protein processing, energy metabolism, and signaling pathways, and suggests novel disease mechanisms
    • DOI 10.1002/ajmg.b.30195
    • Zhang Y., James M., Middleton F. A., Davis R. L., Transcriptional analysis of multiple brain regions in Parkinson's disease supports the involvement of specific protein processing, energy metabolism, and signaling pathways, and suggests novel disease mechanisms. American Journal of Medical Genetics. Part B 2005 137 1 5 16 2-s2.0-23044502947 10.1002/ajmg.b.30195 (Pubitemid 41076605)
    • (2005) American Journal of Medical Genetics - Neuropsychiatric Genetics , vol.137 B , Issue.1 , pp. 5-16
    • Zhang, Y.1    James, M.2    Middleton, F.A.3    Davis, R.L.4
  • 198
    • 84862819237 scopus 로고    scopus 로고
    • The possible mechanism of silver nanoparticle impact on hippocampal synaptic plasticity and spatial cognition in rats
    • 10.1016/j.toxlet.2012.01.001
    • Liu Y., Guan W., Ren G. G., Yang Z., The possible mechanism of silver nanoparticle impact on hippocampal synaptic plasticity and spatial cognition in rats. Toxicology Letters 2012 209 3 227 231 10.1016/j.toxlet.2012.01.001
    • (2012) Toxicology Letters , vol.209 , Issue.3 , pp. 227-231
    • Liu, Y.1    Guan, W.2    Ren, G.G.3    Yang, Z.4
  • 200
    • 84155172825 scopus 로고    scopus 로고
    • Cytotoxic and genotoxic effects of silver nanoparticles in testicular cells
    • 10.1016/j.tox.2011.10.022
    • Asare N., Instanes C., Sandberg W. J., Refsnes M., Schwarze P., Kruszewski M., Brunborg G., Cytotoxic and genotoxic effects of silver nanoparticles in testicular cells. Toxicology 2012 291 1-3 65 72 10.1016/j.tox.2011.10.022
    • (2012) Toxicology , vol.291 , Issue.1-3 , pp. 65-72
    • Asare, N.1    Instanes, C.2    Sandberg, W.J.3    Refsnes, M.4    Schwarze, P.5    Kruszewski, M.6    Brunborg, G.7
  • 202
    • 84861185887 scopus 로고    scopus 로고
    • The similar neurotoxic effects of nanoparticulate and ionic silver in vivo and in vitro
    • 10.1016/j.neuro.2012.04.008
    • Hadrup N., Loeschner K., Mortensen A., Sharma A. K., Qvortrup K., Larsen E. H., Lam H. R., The similar neurotoxic effects of nanoparticulate and ionic silver in vivo and in vitro. Neurotoxicology 2012 33 3 416 423 10.1016/j.neuro.2012.04.008
    • (2012) Neurotoxicology , vol.33 , Issue.3 , pp. 416-423
    • Hadrup, N.1    Loeschner, K.2    Mortensen, A.3    Sharma, A.K.4    Qvortrup, K.5    Larsen, E.H.6    Lam, H.R.7
  • 203
    • 84860247101 scopus 로고    scopus 로고
    • Reactive nitroxidative species and nociceptive processing: Determining the roles for nitric oxide, superoxide, and peroxynitrite in pain
    • 2-s2.0-77953344323 10.1007/s00726-010-0633-0
    • Little J. W., Doyle T., Salvemini D., Reactive nitroxidative species and nociceptive processing: determining the roles for nitric oxide, superoxide, and peroxynitrite in pain. Amino Acids 2012 42 1 75 94 2-s2.0-77953344323 10.1007/s00726-010-0633-0
    • (2012) Amino Acids , vol.42 , Issue.1 , pp. 75-94
    • Little, J.W.1    Doyle, T.2    Salvemini, D.3
  • 204
    • 84866292862 scopus 로고    scopus 로고
    • Four types of inorganic nanoparticles stimulate the inflammatory reaction in brain microglia and damage neurons in vitro
    • 10.1016/j.toxlet.2012.08.009
    • Xue Y., Wu J., Sun J., Four types of inorganic nanoparticles stimulate the inflammatory reaction in brain microglia and damage neurons in vitro. Toxicology Letters 2012 214 2 91 98 10.1016/j.toxlet.2012.08.009
    • (2012) Toxicology Letters , vol.214 , Issue.2 , pp. 91-98
    • Xue, Y.1    Wu, J.2    Sun, J.3
  • 206
    • 84864499587 scopus 로고    scopus 로고
    • Neurological impacts from inhalation of pollutants and the nose-brain connection
    • 10.1016/j.neuro.2011.12.001
    • Lucchini R. G., Dorman D. C., Elder A., Veronesi B., Neurological impacts from inhalation of pollutants and the nose-brain connection. Neurotoxicology 2012 33 4 838 841 10.1016/j.neuro.2011.12.001
    • (2012) Neurotoxicology , vol.33 , Issue.4 , pp. 838-841
    • Lucchini, R.G.1    Dorman, D.C.2    Elder, A.3    Veronesi, B.4
  • 207
    • 71849109449 scopus 로고    scopus 로고
    • Urban air pollution: Influences on olfactory function and pathology in exposed children and young adults
    • 2-s2.0-71849109449 10.1016/j.etp.2009.02.117
    • Calderon-Garciduenas L., Franco-Lira M., Henriquez-Roldan C., Urban air pollution: influences on olfactory function and pathology in exposed children and young adults. Experimental and Toxicologic Pathology 2010 62 1 91 102 2-s2.0-71849109449 10.1016/j.etp.2009.02.117
    • (2010) Experimental and Toxicologic Pathology , vol.62 , Issue.1 , pp. 91-102
    • Calderon-Garciduenas, L.1    Franco-Lira, M.2    Henriquez-Roldan, C.3
  • 208
    • 0038408929 scopus 로고    scopus 로고
    • Olfaction in neurodegenerative disorder
    • DOI 10.1002/mds.10379
    • Hawkes C., Olfaction in neurodegenerative disorder. Movement Disorders 2003 18 4 364 372 2-s2.0-0038408929 10.1002/mds.10379 (Pubitemid 36527276)
    • (2003) Movement Disorders , vol.18 , Issue.4 , pp. 364-372
    • Hawkes, C.1
  • 209
    • 37349030191 scopus 로고    scopus 로고
    • Olfactory dysfunction in Parkinson's disease
    • 2-s2.0-37349030191 10.1159/000109757
    • Kranick S. M., Duda J. E., Olfactory dysfunction in Parkinson's disease. NeuroSignals 2007 16 1 35 40 2-s2.0-37349030191 10.1159/000109757
    • (2007) NeuroSignals , vol.16 , Issue.1 , pp. 35-40
    • Kranick, S.M.1    Duda, J.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.