Structure of the Alzheimer's disease amyloid precursor protein copper binding domain. A regulator of neuronal copper homeostasis

Journal of Biological Chemistry

Volumn 278, Issue 19, 2003, Pages 17401-17407

  Barnham, Kevin J ^d   McKinstry, William J ^a   Multhaup, Gerd ^b   Galatis, Denise ^d   Morton, Craig J ^a   Curtain, Cyril C ^d   Williamson, Nicholas A ^d   White, Anthony R ^d   Hinds, Mark G ^d   Norton, Raymond S ^d   Beyreuther, Konrad ^c   Masters, Colin L ^d   Parker, Michael W ^a   Cappai, Roberto ^d  

^a ST VINCENT'S INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; COORDINATION REACTIONS; DISEASE CONTROL; FREE RADICALS; PROTEINS;

HOMOLOGY;

BIOMEDICAL ENGINEERING;

AMYLOID PRECURSOR PROTEIN; COPPER;

ALZHEIMER DISEASE; ARTICLE; COPPER BINDING DOMAIN; DEGENERATIVE DISEASE; ELECTRON SPIN RESONANCE; GENE EXPRESSION; HOMEOSTASIS; KNOCKOUT MOUSE; MOUSE; NERVE CELL; NEUROLOGIC DISEASE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; AMINO ACID SEQUENCE; BINDING SITE; CHEMISTRY; HUMAN; METABOLISM; MOLECULAR GENETICS; PROTEIN BINDING; PROTEIN CONFORMATION; TRANSPORT AT THE CELLULAR LEVEL;

MUS MUSCULUS;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN PRECURSOR; BINDING SITES; BIOLOGICAL TRANSPORT; COPPER; HUMANS; MOLECULAR SEQUENCE DATA; NEURONS; PROTEIN BINDING; PROTEIN CONFORMATION;

EID: 0037931743     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M300629200     Document Type: Article

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