Microglial expression of MHC class II increases in normal aging of nonhuman primates

Neurobiology of Aging

Volumn 19, Issue 1, 1998, Pages 47-55

  Sheffield, L G ^a   Berman, N E J ^a  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

Aging; Brain; Cortex; MHC class II; Microglia; Monkeys; Primates; White matter

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MYELIN;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; GRAY MATTER; HUMAN TISSUE; MACACA; MICROGLIA; MONKEY; NEUROLOGIC DISEASE; NONHUMAN; PRIMATE; PRIORITY JOURNAL; WHITE MATTER;

AGING; ANIMALS; BRAIN CHEMISTRY; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, MHC CLASS II; IMAGE PROCESSING, COMPUTER-ASSISTED; MACACA NEMESTRINA; MICROGLIA;

EID: 0031960498     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-4580(97)00168-1     Document Type: Article

References (68)

1. Albert M. Neuropsychological and neurophysiological changes in healthy adult humans across the age range. Neurobiol. Aging. 14:1993;623-625.
2. Baloyannis S. J., Costa V., Psaroulis D., Arzoglou L., Papasotiriou M. The nucleus basalis of Meynert of the human brain: A Golgi and electron microscope study. Int. J. Neurosci. 78:1994;33-41.
3. Banati R. B., Gehrmann J., Schubert P., Kreutzberg G. W. Cytotoxicity of microglia. Glia. 7:1993;111-118.
4. Birren J. E., Fisher L. M. Aging and speed of behavior: Possible consequences for psychological functioning. Annu. Rev. Psychol. 46:1995;329-353.
5. Braak H., Braak E. Development of Alzheimer-related neurofibrillary changes in the neocortex inversely recapitulates cortical myelogenesis. Acta Neuropathol. 92:1996;197-201.
6. Carpenter A. F., Carpenter P. W., Markesbery W. R. Morphometric analysis of microglia in Alzheimer's disease. J. Neuropathol. Exp. Neurol. 52:1993;601-608.
7. Coggeshall R. E., Lekan H. A. Methods for determining numbers of cells and synapses: A case for more uniform standards of review. J. Comp. Neurol. 364:1996;6-15.
8. Cras P., Kawai M., Siedlak S., Perry G. Microglia are associated with the extracellular neurofibrillary tangles of Alzheimer disease. Brain Res. 558:1991;312-314.
9. Davis E. J., Foster T. D., Thomas W. E. Cellular forms and functions of brain microglia. Brain Res. Bull. 34:1994;73-78.
10. del Rio-Hortega P. Microglia. Penfield W. Cytology and Cellular Pathology of the Nervous System. Vol. 2:1932;481-534 Hoeber, New York.
11. Dickson D. W., Lee S. C. Microglia. Davis R. L., Robertson D. M. Textbook of Neuropathology. third edition. 1997;165-205 Williams & Wilkins, Baltimore.
12. Dickson D. W., Mattiace L. A., Kure K., Hutchins K., Lyman W. D., Brosnan C. F. Microglia in human disease, with an emphasis on acquired immune deficiency syndrome. Lab. Invest. 64:1991;135-156.
13. Dickson D. W., Sinicropi S., Yen S.-H., Ko L.-W., Mattiace L. A., Bucala R., Vlassara H. Glycation and microglial reaction in lesions of Alzheimer's disease. Neurobiol. Aging. 17:1996;733-743.
14. Dickson D. W., Wertkin A., Kress Y., Ksiezak-Redking H., Yen S.-H. Ubiquitin immunoreactive structures in normal human brains: Distribution and developmental aspects. Lab. Invest. 63:1990;87-99.
15. Eckenhoff M. F., Rakic P. Nature and fate of proliferative cells in the hippocampal dentate gyrus during the life span of the rhesus monkey. J. Neurosci. 8:1988;2729-2747.
16. Gómez-Isla T., Hollister R., West H., Mui S., Growdon J. H., Petersen R. C., Parisi J. E., Hyman B. T. Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease. Ann. Neurol. 41:1997;17-24.
17. Gómez-Isla T., Price J. L., McKeel D. W. Jr, Morris J. C., Growdon J. H., Hyman B. T. Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer's disease. J. Neurosci. 16:1996;4491-4500.
18. Grau V., Herbst B., van der Meide P. H., Steiniger B. Activation of microglial and endothelial cells in the rat brain after treatment with interferon-γ in vivo. Glia. 19:1997;181-189.
19. Haug H. Are neurons of the human cerebral cortex really lost during aging? A morphometric examination. Traber J., Gispen W. H. Senile Dementia of the Alzheimer Type. 1985;150-163 Springer-Verlag, Berlin.
20. Haug H., Eggers R. Morphometry of the human cortex cerebri and corpus striatum during aging. Neurobiol. Aging. 12:1991;336-338.
21. Haug H., Kühl S., Mecke E., Sass N. L., Wasner K. The significance of morphometric procedures in the investigation of age changes in cytoarchitectonic structures of human brain. J. Hirnforsch. 25:1984;353-374.
22. Herndon J. G., Moss M. B., Rosene D. L., Killiany R. J. Age-related changes in the rhesus monkey: Patterns of cognitive decline. Soc. Neurosci. Abst. 22:1996;1237.
23. Hurtrel B., Chakrabarti L., Hurtrel M., Montagnier L. Target cells during early SIV encephalopathy. Res. Virol. 144:1993;41-46.
24. Jacobs B., Scheibel A. B. A quantitative dendritic analysis of Wernicke's area in humans. I. Lifespan changes. J. Comp. Neurol. 327:1993;83-96.
25. Kemper T. L. Neuroanatomical and neuropathological changes during aging and dementia. Albert M. L., Knoefel J. E. Clinical Neurology and Aging. 1994;3-67 Oxford University Press, New York.
26. Kim C. B. Y., Pier L. P., Spear P. D. Effects of aging on numbers and sizes of neurons in histochemically defined subregions of monkey striate cortex. Anat. Rec. 247:1997;119-128.
27. Lackner A. A., Smith M. O., Munn R. J., Martfeld D. J., Gardner M. B., Marx P. A., Dandekar S. Localization of simian immunodeficiency virus in the central nervous system of rhesus monkeys. Am. J. Pathol. 139:1991;609-621.
28. Lintl P., Braak H. Loss of intracortical myelinated fibers: A distinctive age-related alteration in the human striate area. Acta Neuropathol. 61:1983;178-182.
29. Luber-Narod J., Rogers J. Immune system associated antigens expressed by cells of the human central nervous system. Neurosci. Lett. 94:1988;17-22.
30. Manaye K. F., McIntire D. D., Mann D. M. A., German D. C. Locus coeruleus cell loss in the aging human brain: A non-random process. J. Comp. Neurol. 358:1995;79-87.
31. Mattiace L. A., Davies P., Dickson D. W. Detection of HLA-DR on microglia in the human brain is a function of both clinical and technical factors. Am. J. Pathol. 136:1990;1101-1114.
32. Maxwell S. E., Delaney H. D. Designing experiments and analyzing data: A model comparison perspective. 1990;Wadsworth Publishing Co, Belmont, CA.
33. McGeer P. L., Itagaki S., Tago H., McGeer E. G. Reactive microglia in patients with senile dementia of the Alzheimer type are positive for the histocompatibility glycoprotein HLA-DR. Neurosci. Lett. 79:1987;195-200.
34. McRae A., Dahlström A., Ling E. A. Microglial in neurodegenerative disorders: Emphasis on Alzheimer's disease. Gerontology. 43:1997;95-108.
35. Merrill J. E., Ignarro L. J., Sherman M. P., Melinek J., Lane T. E. Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide. J. Immunol. 151:1993;2132-2141.
36. Mitrovic B., Ignarro L. J., Montestruque S., Smoll A., Merrill J. E. Nitric oxide as a potential pathological mechanism in demyelination: Its differential effects on primary glial cells in vitro. Neuroscience. 61:1994;575-585.
37. Mizutani T., Shimada H. Neuropathological background of twenty-seven centenarian brains. J. Neurol. Sci. 108:1992;168-177.
38. Moss M. B., Killiany R. J., Lai Z. C., Rosene D. L., Herndon J. G. Recognition memory span in rhesus monkeys of advanced age. Neurobiol. Aging. 18:1997;13-19.
39. Moss M. B., Killiany R. J., Rosene D. L., Herndon J. Age-related changes in the rhesus monkey: Recognition memory in the oldest of the old. Soc. Neurosci. Abst. 22:1996;1237.
40. Mouton P. R., Pakkenberg B., Gundersen H. J. G., Price D. L. Absolute number and size of pigmented locus coeruleus neurons in young and aged individuals. J. Chem. Neuroanat. 7:1994;185-190.
41. Münch G., Thome J., Foley P., Schinzel R., Riederer P. Advanced glycation end products in ageing and Alzheimer's disease. Brain Res. Rev. 23:1997;134-143.
42. Ogura K., Ogawa M., Yoshida M. Effects of ageing on microglia in the normal rat brain: Immunohistochemical observations. NeuroReport. 5:1994;1224-1226.
43. Pakkenberg H., Andersen B. B., Burns R. S., Pakkenberg B. A stereological study of substantia nigra in young and old rhesus monkeys. Brain Res. 693:1995;201-206.
44. Perlmutter L. S., Scott S. A., Barrón E., Chui H. C. MHC class II-positive microglia in human brain: Association with Alzheimer lesions. J. Neurosci. Res. 33:1992;549-558.
45. Perlmutter L. S., Scott S. A., Chui H. C. The role of microglia in the cortical neuropathology of Alzheimer disease. Bull. Clin. Neurosci. 56:1991;120-130.
46. Perry V. H., Andersson P.-B., Gordon S. Macrophages and inflammation in the central nervous system. Trends Neurosci. 16:1993;268-273.
47. Perry V. H., Gordon S. Macrophages and the nervous system. Int. Rev. Cytol. 125:1991;203-244.
48. Peters A. Aging in monkey cerebral cortex. Peters A., Jones E. G. Normal and Altered States of Function, Cerebral Cortex. 1991;485-510 Plenum Press, New York.
49. Peters A., Josephson K., Vincent S. L. Effects of aging on the neuroglial cells and pericytes within area 17 of the rhesus monkey cerebral cortex. Anat. Rec. 229:1991;384-398.
50. Peters A., Leahu D., Moss M. B., McNally K. J. The effects of aging on area 46 of the frontal cortex of the rhesus monkey. Cereb. Cortex. 6:1994;621-635.
51. Peters A., Nigro N. J., McNally K. J. A further evaluation of the effect of age on striate cortex of the rhesus monkey. Neurobiol. Aging. 18:1997;29-36.
52. Peters A., Rosene D. L., Moss M. B., Kemper T. L., Abraham C. R., Tigges J., Albert M. S. Neurobiological bases of age-related cognitive decline in the rhesus monkey. J. Neuropathol. Exp. Neurol. 55:1996;861-874.
53. Presty S. K., Bachevalier J., Walker L. C., Struble R. G., Price D. L., Mishkin M., Cork L. C. Age differences in recognition memory of the rhesus monkey (Macaca mulatta). Neurobiol. Aging. 8:1987;435.
54. Price D. L., Koo E. H., Walker L. C., Applegate M. D., Wagster M. V., Wenk G. L., Struble R. G., Cork L. C. Abnormalities of behavior and brain in aged nonhuman primates. Finch C. E., Davies P. Current Communications in Molecular Biology The Molecular Biology of Alzheimer's Disease . 1988;57-60 Cold Spring Harbor Laboratory, New York.
55. Rogers J., Luber-Narod J., Styren S. D., Civin W. H. Expression of immune system-associated antigens by cells of the human central nervous system: Relationship to the pathology of Alzheimer's disease. Neurobiol. Aging. 9:1988;339-349.
56. Samorajski T. How the human brain responds to aging. J. Am. Geriatr Soc. 24:1976;4-11.
57. Sasaki A., Nakanishi Y., Nakazato Y., Yamaguchi H. Application of lectin and B-lymphocyte-specific monoclonal antibodies for the demonstration of human microglia in formalin-fixed, paraffin-embedded brain tissue. Virchows Arch. A. Pathol. Anat. Histopathol. 419:1991;291-299.
58. Sheffield L. G., Purcell J. A., Berman N. E. J. Microglial activation in monkeys with age. Soc. Neurosci. Abst. 21:1995;470.
59. Steiniger B., van der Meide P. H. Rat ependyma and microglia cells express class II MHC antigens after intravenous infusion of recombinant gamma interferon. J. Neuroimmunol. 19:1988;111-118.
60. Styren S. D., Civin W. H., Rogers J. Molecular, cellular, and pathologic characterization of HLA-DR immunoreactivity in normal elderly and Alzheimer's disease brain. Exp. Neurol. 110:1990;93-104.
61. Swearer J. M., Kane K. J. Behavioral slowing with age Boundary conditions of the generalized slowing model . J. Gerontol. Psychol. Sci. 51B:1996;P189-P200.
62. Terry R. D., DeTeresa R., Hansen L. A. Neocortical cell counts in normal human adult aging. Ann. Neurol. 21:1987;530-539.
63. Thomas W. E. Brain macrophages: Evaluation of microglia and their functions. Brain Res. Rev. 17:1992;61-74.
64. Tigges J., Gordon T. P., McClure H. M., Hall E. C., Peters A. Survival rate and life span of rhesus monkeys at the Yerkes Regional Primate Research Center. Am. J. Primatol. 15:1988;263-273.
65. Tigges J., Herndon J. G., Peters A. Neuronal population of area 4 during the life span of the rhesus monkey. Neurobiol. Aging. 11:1990;201-208.
66. Voytko M. L., Sukhov R. R., Walker L. C., Breckler S. J., Price D. L., Koliatsos V. E. Neuronal number and size are preserved in the nucleus basalis of aged rhesus monkeys. Dementia. 6:1995;131-141.
67. West M. J., Coleman P. D., Flood D. G., Troncoso J. C. Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease. Lancet. 344:1994;769-772.
68. Ylikoski A., Erkinjuntti T., Raininko R., Sarna S., Sulkava R., Tilvis R. White matter hyperintensities on MRI in the neurologically nondiseased elderly: Analysis of cohorts of consecutive subjects aged 55 to 85 years living at home. Stroke. 26:1995;1171-1177.