Adventiously-bound redox active iron and copper are at the center of oxidative damage in Alzheimer disease

BioMetals

Volumn 16, Issue 1, 2003, Pages 77-81

  Perry, George ^a   Taddeo, Marta A ^a   Petersen, Robert B ^a   Castellani, Rudy J ^a   Harris, Peggy L R ^a   Siedlak, Sandra L ^a   Cash, Adam D ^a   Liu, Quan ^a   Nunomura, Akohiko ^b   Atwood, Craig S ^a   Smith, Mark A ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b ASAHIKAWA MEDICAL COLLEGE   (Japan)

Author keywords

Alzheimer disease; Copper; Iron; Mitochondria; Oxidative stress; Redox metals

Indexed keywords

AMYLOID BETA PROTEIN; APOLIPOPROTEIN E; BILIVERDIN; COPPER; CYTOCHROME C OXIDASE; DEFEROXAMINE; HEME OXYGENASE 1; HYDROXYL RADICAL; IRON; MITOCHONDRIAL DNA; NUCLEIC ACID; PENTETIC ACID; RNA; TAU PROTEIN;

ALZHEIMER DISEASE; BINDING SITE; BRAIN MITOCHONDRION; CONFERENCE PAPER; CONTROLLED STUDY; CYTOSOL; DISEASE ACTIVITY; ENZYME ACTIVITY; HUMAN; IRON CHELATION; MACROMOLECULE; METAL BINDING; MICROTUBULE; NERVE CELL; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PYRAMIDAL NERVE CELL;

ALZHEIMER DISEASE; BRAIN; COPPER; ELECTRON TRANSPORT COMPLEX IV; HUMANS; HYDROXYL RADICAL; IRON; MODELS, NEUROLOGICAL; OXIDATION-REDUCTION; OXIDATIVE STRESS;

EID: 0037355733     PISSN: 09660844     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1020731021276     Document Type: Conference Paper

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