Age-related differences in NFκB translocation and Bcl-2/Bax ratio caused by TNFα and Abeta42 promote survival in middle-age neurons and death in old neurons

Experimental Neurology

Volumn 213, Issue 1, 2008, Pages 93-100

  Patel, Jigisha R ^a   Brewer, Gregory J ^a  

^a SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Blocking antibodies; Cortical neurons; TNFR1; TNFR2

Indexed keywords

AMYLOID BETA PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN ABETA2; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P50; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL AGING; CELL DEATH; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; GENE TRANSLOCATION; MALE; NERVE CELL; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT;

ACTIVE TRANSPORT, CELL NUCLEUS; AGING; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BRAIN; CELL DEATH; CELL SURVIVAL; CELLS, CULTURED; MALE; NERVE DEGENERATION; NEURONS; NF-KAPPA B; PEPTIDE FRAGMENTS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, INBRED F344; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE II; TUMOR NECROSIS FACTOR-ALPHA;

EID: 49349097514     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2008.05.007     Document Type: Article

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