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Volumn 26, Issue 1, 2011, Pages 81-104

Selenium and alzheimer's disease: A systematic review

Author keywords

Alzheimer's disease; amyloid ; dementia; NF B; oxidative stress; selenium; selenoproteins; systematic review trace elements; tau

Indexed keywords

ALPHA TOCOPHEROL; AMYLOID BETA PROTEIN; CELL MEMBRANE PROTEIN; COLOSTRININ; GLUTATHIONE PEROXIDASE; HOMOCYSTEINE; METHIONINE SULFOXIDE REDUCTASE B; PLACEBO; POLYUNSATURATED FATTY ACID; PROLINE RICH PROTEIN; SELENIUM; SELENIUM DERIVATIVE; SELENOMETHIONINE; SELENOPROTEIN M; SODIUM SELENITE; STREPTOCYTOCIN; TAU PROTEIN; THIOREDOXIN REDUCTASE; UNCLASSIFIED DRUG;

EID: 80052837908     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-2011-110414     Document Type: Review
Times cited : (153)

References (299)
  • 1
    • 0034662094 scopus 로고    scopus 로고
    • The importance of selenium to human health
    • Rayman MP (2000) The importance of selenium to human health. The Lancet 356, 233-241. (Pubitemid 30446984)
    • (2000) Lancet , vol.356 , Issue.9225 , pp. 233-241
    • Rayman, M.P.1
  • 2
    • 67650805623 scopus 로고    scopus 로고
    • The human selenopro-teome: Recent insights into functions and regulation
    • Reeves MA, Hoffmann PR (2009) The human selenopro-teome: recent insights into functions and regulation. Cell Mol Life Sci 66, 2457-2478.
    • (2009) Cell Mol Life Sci , vol.66 , pp. 2457-2478
    • Reeves, M.A.1    Hoffmann, P.R.2
  • 3
    • 68749110874 scopus 로고    scopus 로고
    • Regulation and function of selenoproteins in human disease
    • Bellinger FP, Raman AV, Reeves MA, Berry MJ (2009) Regulation and function of selenoproteins in human disease. Biochem J 422, 11-22.
    • (2009) Biochem J , vol.422 , pp. 11-22
    • Bellinger, F.P.1    Raman, A.V.2    Reeves, M.A.3    Berry, M.J.4
  • 4
    • 34250318625 scopus 로고    scopus 로고
    • From selenium to selenoproteins: Synthesis, identity, and their role in human health
    • DOI 10.1089/ars.2007.1528
    • Papp LV, Lu J, Holmgren A, Khanna KK (2007) From selenium to selenoproteins: synthesis, identity, and their role in human health. Antioxid Redox Signal 9, 775-806. (Pubitemid 46919583)
    • (2007) Antioxidants and Redox Signaling , vol.9 , Issue.7 , pp. 775-806
    • Papp, L.V.1    Lu, J.2    Holmgren, A.3    Khanna, K.K.4
  • 6
    • 0042023711 scopus 로고    scopus 로고
    • Alzheimer disease in the US population: Prevalence estimates using the 2000 census
    • DOI 10.1001/archneur.60.8.1119
    • Hebert LE, Scherr PA, Bienias JL, Bennett DA, Evans DA (2003) Alzheimer disease in the US population: prevalence estimates using the 2000 census. Arch Neurol 60, 1119-1122. (Pubitemid 36975801)
    • (2003) Archives of Neurology , vol.60 , Issue.8 , pp. 1119-1122
    • Hebert, L.E.1    Scherr, P.A.2    Bienias, J.L.3    Bennett, D.A.4    Evans, D.A.5
  • 8
    • 0035066332 scopus 로고    scopus 로고
    • Alzheimer's disease: Genes, proteins, and therapy
    • Selkoe DJ (2001) Alzheimer's disease: genes, proteins, and therapy. Physiol Rev 81, 741-766. (Pubitemid 32267077)
    • (2001) Physiological Reviews , vol.81 , Issue.2 , pp. 741-766
    • Selkoe, D.J.1
  • 9
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
    • DOI 10.1126/science.1072994
    • Hardy J, Selkoe DJ (2002) The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 297, 353-356. (Pubitemid 34790756)
    • (2002) Science , vol.297 , Issue.5580 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 10
    • 0032902974 scopus 로고    scopus 로고
    • Oxidative alterations in Alzheimer's disease
    • Markesbery WR, Carney JM (1999) Oxidative alterations in Alzheimer's disease. Brain Pathol 9, 133-146. (Pubitemid 29056524)
    • (1999) Brain Pathology , vol.9 , Issue.1 , pp. 133-146
    • Markesbery, W.R.1    Carney, J.M.2
  • 11
    • 0030915855 scopus 로고    scopus 로고
    • Oxidative stress hypothesis in Alzheimer's disease
    • DOI 10.1016/S0891-5849(96)00629-6, PII S0891584996006296
    • Markesbery WR (1997) Oxidative stress hypothesis in Alzheimer's disease. Free Radic Biol Med 23, 134-147. (Pubitemid 27217017)
    • (1997) Free Radical Biology and Medicine , vol.23 , Issue.1 , pp. 134-147
    • Markesbery, W.R.1
  • 12
    • 34548036227 scopus 로고    scopus 로고
    • Tau-mediated neurodegeneration in Alzheimer's disease and related disorders
    • DOI 10.1038/nrn2194, PII NRN2194
    • Ballatore C, Virginia VM, Trojanowski JK (2007) Tau-mediated neurodegeneration in Alzheimer's disease and related disorders. Nat Rev Neurosci 8, 663-672. (Pubitemid 47283144)
    • (2007) Nature Reviews Neuroscience , vol.8 , Issue.9 , pp. 663-672
    • Ballatore, C.1    Lee, V.M.-Y.2    Trojanowski, J.Q.3
  • 13
    • 0025863618 scopus 로고
    • Neuropathological stageing of Alzheimer-related changes
    • Braak H, Braak E (1991) Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol 82, 239-259.
    • (1991) Acta Neuropathol , vol.82 , pp. 239-259
    • Braak, H.1    Braak, E.2
  • 14
    • 0042508791 scopus 로고    scopus 로고
    • Neuropathologic changes in Alzheimer's disease
    • Wenk GL (2003) Neuropathologic changes in Alzheimer's disease. J Clin Psychiatr 64 Suppl 9, 7-10. (Pubitemid 37040372)
    • (2003) Journal of Clinical Psychiatry , vol.64 , Issue.SUPPL. 9 , pp. 7-10
    • Wenk, G.L.1
  • 15
    • 77952553133 scopus 로고    scopus 로고
    • Selenopro-teins and the aging brain
    • Zhang C, Caroline Rocourt, Cheng WH (2010) Selenopro-teins and the aging brain. Mech Ageing Dev 131, 253-260.
    • (2010) Mech Ageing Dev , vol.131 , pp. 253-260
    • Zhang, C.1    Rocourt, C.2    Cheng, W.H.3
  • 16
    • 60349123777 scopus 로고    scopus 로고
    • Increased selenium intake in elderly high fish consumers may account for health benefits previously ascribed to omega-3 fatty acids
    • Berr C, Akbaraly T, Arnaud J, Hininger I, Roussel AM, Bar-berger Gateau P (2009) Increased selenium intake in elderly high fish consumers may account for health benefits previously ascribed to omega-3 fatty acids. J Nutr Health Aging 13, 14-18.
    • (2009) J Nutr Health Aging , vol.13 , pp. 14-18
    • Berr, C.1    Akbaraly, T.2    Arnaud, J.3    Hininger, I.4    Roussel, A.M.5    Bar-Berger Gateau, P.6
  • 17
    • 0000616802 scopus 로고
    • Factor 3 activity of selenium compounds
    • Schwarz K, Foltz CM (1958) Factor 3 activity of selenium compounds. J Biol Chem 233, 245-251.
    • (1958) J Biol Chem , vol.233 , pp. 245-251
    • Schwarz, K.1    Foltz, C.M.2
  • 19
    • 3242666571 scopus 로고    scopus 로고
    • Institute of Medicine Dietary Reference Intakes: Vitamin C, Vitamin E, Selenium and Carotenoids, National Academy Press, Washington DC
    • National Academy of Sciences. Institute of Medicine (2000), Dietary Reference Intakes: Vitamin C, Vitamin E, Selenium and Carotenoids, National Academy Press, Washington DC.
    • (2000) National Academy of Sciences
  • 20
    • 1842423444 scopus 로고    scopus 로고
    • Assessment of requirements for selenium and adequacy of selenium status: A review
    • DOI 10.1038/sj.ejcn.1601800
    • Thomson CD (2004) Assessment of requirements for selenium and adequacy of selenium status: a review. Eur J Clin Nutr 58, 391-402. (Pubitemid 38443698)
    • (2004) European Journal of Clinical Nutrition , vol.58 , Issue.3 , pp. 391-402
    • Thomson, C.D.1
  • 21
    • 0342467931 scopus 로고    scopus 로고
    • Selenium in global food systems
    • Combs GF Jr (2007) Selenium in global food systems. Br J Nutr 85, 517-547.
    • (2007) Br J Nutr , vol.85 , pp. 517-547
    • Combs Jr., G.F.1
  • 23
    • 0035114097 scopus 로고    scopus 로고
    • Serum concentrations of zinc and selenium in elderly people: Results in healthy nonagenarians/centenarians
    • DOI 10.1016/S0531-5565(00)00218-7, PII S0531556500002187
    • Savarino L, Granchi D, Ciapetti G, Cenni E, Ravaglia G, Forti P, Maioli F, Mattioli R (2001) Serum concentrations of zinc and selenium in elderly people: results in healthy nonagenarians/centenarians. Exp Gerontol 36, 327-339. (Pubitemid 32164435)
    • (2001) Experimental Gerontology , vol.36 , Issue.2 , pp. 327-339
    • Savarino, L.1    Granchi, D.2    Ciapetti, G.3    Cenni, E.4    Ravaglia, G.5    Forti, P.6    Maioli, F.7    Mattioli, R.8
  • 24
    • 0030940819 scopus 로고    scopus 로고
    • Genomic structures of viral agents in relation to the biosynthesis of selenoproteins
    • Taylor EW, Nadimpalli RG, Ramanathan CS (1997) Genomic structures of viral agents in relation to the biosynthesis of selenoproteins. Biol Trace Elem Res 56, 63-91 (Pubitemid 27198251)
    • (1997) Biological Trace Element Research , vol.56 , Issue.1 , pp. 63-91
    • Taylor, E.W.1    Nadimpalli, R.G.2    Ramanathan, C.S.3
  • 25
    • 33646236290 scopus 로고    scopus 로고
    • United States Department of Agriculture usda.gov/nal display/index.php? tax level =1&info center=4&tax subject=279 Accessed September 07, 2010
    • United States Department of Agriculture (2010) National Nutrient Database for Standard Reference, Release 22, http://fnic.nal.usda.gov/nal display/index.php?tax level =1&info center=4&tax subject=279, Accessed September 07, 2010.
    • (2010) National Nutrient Database for Standard Reference, Release , vol.22
  • 26
    • 0031794470 scopus 로고    scopus 로고
    • Lessons from basic research in selenium and cancer prevention
    • Ip C (1998) Lessons from basic research in selenium and cancer prevention. J Nutr 128, 1845-1854. (Pubitemid 28509845)
    • (1998) Journal of Nutrition , vol.128 , Issue.11 , pp. 1845-1854
    • Ip, C.1
  • 27
    • 0036703297 scopus 로고    scopus 로고
    • Evolutionarily different RNA motifs and RNA-protein complexes to achieve selenoprotein synthesis
    • DOI 10.1016/S0300-9084(02)01405-0, PII S0300908402014050
    • Krol A (2002) Evolutionarily different RNA motifs and RNA-protein complexes to achieve selenoprotein synthesis. Biochimie 84, 765-774. (Pubitemid 35363461)
    • (2002) Biochimie , vol.84 , Issue.8 , pp. 765-774
    • Krol, A.1
  • 29
    • 0025912639 scopus 로고
    • The cDNA for rat selenoprotein P contains 10 TGA codons in the open reading frame
    • Hill KE, Lloyd RS, Yang JG, Read R, Burk RF (1991) The cDNA for rat selenoprotein P contains 10 TGA codons in the open reading frame. J Biol Chem 266, 10050-10053.
    • (1991) J Biol Chem , vol.266 , pp. 10050-10053
    • Hill, K.E.1    Lloyd, R.S.2    Yang, J.G.3    Read, R.4    Burk, R.F.5
  • 31
    • 0037337666 scopus 로고    scopus 로고
    • Gene disruption discloses role of selenoprotein P in selenium delivery to target tissues
    • DOI 10.1042/BJ20021853
    • Schomburg L, Schweizer U, Holtmann B, Flohé L, Sendtner M, Köhrle J (2003) Gene disruption discloses role of seleno-protein P in selenium delivery to target tissues. Biochem J 370, 397-402. (Pubitemid 36315127)
    • (2003) Biochemical Journal , vol.370 , Issue.2 , pp. 397-402
    • Schomburg, L.1    Schweizer, U.2    Holtmann, B.3    Flohe, L.4    Sendtner, M.5    Kohrle, J.6
  • 32
    • 0033614046 scopus 로고    scopus 로고
    • Selenoprotein P in human plasma as an extracellular phospholipid hydroperoxide glu-tathione peroxidase
    • Saito Y, Hayashi T, Tanaka A, Watanabe Y, Suzuki M, Saito E, Takahashi K (1999) Selenoprotein P in human plasma as an extracellular phospholipid hydroperoxide glu-tathione peroxidase. J Biol Chem 274, 2866-2871.
    • (1999) J Biol Chem , vol.274 , pp. 2866-2871
    • Saito, Y.1    Hayashi, T.2    Tanaka, A.3    Watanabe, Y.4    Suzuki, M.5    Saito, E.6    Takahashi, K.7
  • 33
    • 70449174079 scopus 로고
    • Hemoglobin catabolism. I. Glu-tathione peroxidase, an erythrocyte enzyme which protects hemoglobin from oxidative breakdown
    • Mills GC (1957) Hemoglobin catabolism. I. Glu-tathione peroxidase, an erythrocyte enzyme which protects hemoglobin from oxidative breakdown. J Biol Chem 229, 189-197.
    • (1957) J Biol Chem , vol.229 , pp. 189-197
    • Mills, G.C.1
  • 34
    • 0015880169 scopus 로고
    • Glutathione per-oxidase: A selenoenzyme
    • Flohe L, Günzler WA, Schock HH (1973) Glutathione per-oxidase: a selenoenzyme. FEBS Lett 32, 132-134.
    • (1973) FEBS Lett , vol.32 , pp. 132-134
    • Flohe, L.1    Günzler, W.A.2    Schock, H.H.3
  • 35
    • 0023186348 scopus 로고
    • Purification and characterization of human plasma glutathione peroxidase: A selenoglycoprotein distinct from the known cellular enzyme
    • Takahashi K, Avissar N, Whitin J, Cohen H (1987) Purification and characterization of human plasma glu-tathione peroxidase: a selenoglycoprotein distinct from the known cellular enzyme. Arch Biochem Biophys 256, 677-686. (Pubitemid 17121963)
    • (1987) Archives of Biochemistry and Biophysics , vol.256 , Issue.2 , pp. 677-686
    • Takahashi, K.1    Avissar, N.2    Whitin, J.3    Cohen, H.4
  • 36
    • 35348840292 scopus 로고    scopus 로고
    • Physiological role of phospholipid hydroperoxide glutathione peroxidase in mammals
    • DOI 10.1515/BC.2007.130
    • Conrad M, Schneider M, Seiler A, Bornkamm GW (2007) Physiological role of phospholipid hydroperoxide glutathione peroxidase in mammals. Biol Chem 388, 1019-1025. (Pubitemid 47584306)
    • (2007) Biological Chemistry , vol.388 , Issue.10 , pp. 1019-1025
    • Conrad, M.1    Schneider, M.2    Seiler, A.3    Bornkamm, G.W.4
  • 38
    • 0033775891 scopus 로고    scopus 로고
    • Physiological functions of thioredoxin and thioredoxin reductase
    • Arnér ES, Holmgren A (2000) Physiological functions of thioredoxin and thioredoxin reductase. Eur J Biochem 267, 6102-6109.
    • (2000) Eur J Biochem , vol.267 , pp. 6102-6109
    • Arnér, E.S.1    Holmgren, A.2
  • 42
    • 67649435873 scopus 로고    scopus 로고
    • Selenium prevents cognitive decline and oxidative damage in rat model of streptozotocin-induced experimental dementia of Alzheimer's type
    • Ishrat T, Parveen K, Khan MM, Khuwaja G, Khan MB, Yousuf S, Ahmad A, Shrivastav P, Islam F (2009) Selenium prevents cognitive decline and oxidative damage in rat model of streptozotocin-induced experimental dementia of Alzheimer's type. Brain Res 1281, 117-127.
    • (2009) Brain Res , vol.1281 , pp. 117-127
    • Ishrat, T.1    Parveen, K.2    Khan, M.M.3    Khuwaja, G.4    Khan, M.B.5    Yousuf, S.6    Ahmad, A.7    Shrivastav, P.8    Islam, F.9
  • 43
    • 77954980395 scopus 로고    scopus 로고
    • Protective effects of selenium and zinc on the brain acetyl cholinesterase activity in lead intoxified rat
    • Ani M, Moshtaghie AA, Aghadavood M (2007) Protective effects of selenium and zinc on the brain acetyl cholinesterase activity in lead intoxified rat. Res Pharm Sci 1, 80-84.
    • (2007) Res Pharm Sci , vol.1 , pp. 80-84
    • Ani, M.1    Moshtaghie, A.A.2    Aghadavood, M.3
  • 44
    • 33746910112 scopus 로고    scopus 로고
    • Glutathione peroxidase-1 contributes to the protection of glutamine synthetase in astrocytes during oxidative stress
    • DOI 10.1007/s00702-005-0389-y
    • Knorpp T, Robinson SR, Crack PJ, Dringen R (2006) Glutathione peroxidase-1 contributes to the protection of glutamine synthetase in astrocytes during oxidative stress. J Neural Transm 113, 1145-1155. (Pubitemid 44291010)
    • (2006) Journal of Neural Transmission , vol.113 , Issue.9 , pp. 1145-1155
    • Knorpp, T.1    Robinson, S.R.2    Crack, P.J.3    Dringen, R.4
  • 46
    • 0019972810 scopus 로고
    • The cholinergic hypothesis of geriatric memory dysfunction
    • Bartus RT, Dean RL 3 rd, Beer B, Lippa AS (1982) The cholinergic hypothesis of geriatric memory dysfunction. Science 217, 408-414.
    • (1982) Science , vol.217 , pp. 408-414
    • Bartus, R.T.1    Dean III, R.L.2    Beer, B.3    Lippa, A.S.4
  • 47
    • 0023151640 scopus 로고
    • Presynaptic serotonergic dysfunction in patients with Alzheimer's disease
    • DOI 10.1111/j.1471-4159.1987.tb13120.x
    • Palmer AM, Francis PT, Benton JS, Sims NR, Mann DM, Neary D, Snowden JS, Bowen DM (1987) Presynaptic sero-tonergic dysfunction in patients with Alzheimer's disease. J Neurochem 48, 8-15. (Pubitemid 17031359)
    • (1987) Journal of Neurochemistry , vol.48 , Issue.1 , pp. 8-15
    • Palmer, A.M.1    Francis, P.T.2    Benton, J.S.3
  • 49
    • 0019256571 scopus 로고
    • Reduced somatostatin-like immunoreactivity in cerebral cortex from cases of Alzheimer disease and Alzheimer senile dementia
    • DOI 10.1038/288279a0
    • Davies P, Katzman R, Terry RD (1980) Reduced somatostatin-like immunoreactivity in cerebral cortex from cases of Alzheimer disease and Alzheimer senile dementia. Nature 288, 279-280. (Pubitemid 11165878)
    • (1980) Nature , vol.288 , Issue.5788 , pp. 279-280
    • Davies, P.1    Katzman, R.2    Terry, R.D.3
  • 52
    • 34250024011 scopus 로고    scopus 로고
    • Deletion of apolipoprotein E receptor-2 in mice lowers brain selenium and causes severe neurological dysfunction and death when a low-selenium diet is fed
    • DOI 10.1523/JNEUROSCI.1153-07.2007
    • Burk RF, Hill KE, Olson GE, Weeber EJ, Motley AK, Winfrey VP, Austin LM (2007) Deletion of apolipoprotein E receptor-2 in mice lowers brain selenium and causes severe neurological dysfunction and death when a low-selenium diet is fed. J Neurosci 27, 6207-6211. (Pubitemid 46890009)
    • (2007) Journal of Neuroscience , vol.27 , Issue.23 , pp. 6207-6211
    • Burk, R.F.1    Hill, K.E.2    Olson, G.E.3    Weeber, E.J.4    Motley, A.K.5    Winfrey, V.P.6    Austin, L.M.7
  • 53
    • 27644459819 scopus 로고    scopus 로고
    • Differentially expressed genes in transgenic mice carrying human mutant presenilin-2 (N141I): Correlation of selenoprotein M with Alzheimer's disease
    • DOI 10.1007/s11064-005-6787-6
    • Hwang DY, Cho JS, Oh JH, Shim SB, Jee SW, Lee SH, Seo SJ, Lee SK, Lee SH, Kim YK (2005) Differentially expressed genes in transgenic mice carrying human mutant presenilin-2 (N141I): correlation of selenoprotein M with Alzheimer's disease. Neurochem Res 30, 1009-1019. (Pubitemid 41570036)
    • (2005) Neurochemical Research , vol.30 , Issue.8 , pp. 1009-1019
    • Hwang, D.Y.1    Cho, J.S.2    Oh, J.H.3    Shim, S.B.4    Jee, S.W.5    Lee, S.H.6    Seo, S.J.7    Lee, S.-K.8    Lee, S.H.9    Kim, Y.K.10
  • 56
    • 0025153318 scopus 로고
    • Trace element imbalances in isolated subcellular fractions of Alzheimer's disease brains
    • DOI 10.1016/0006-8993(90)91804-P
    • Wenstrup D, Ehman WD, Markesbery WR (1990) Trace element imbalances in isolated subcellular fractions of Alzheimer's disease brains. Brain Res 533, 125-131. (Pubitemid 20375807)
    • (1990) Brain Research , vol.533 , Issue.1 , pp. 125-131
    • Wenstrup, D.1    Ehmann, W.D.2    Markesbery, W.R.3
  • 57
    • 0346607201 scopus 로고    scopus 로고
    • No evidence for an impact of selenium supplementation on environment associated health disorders - A systematic review
    • DOI 10.1078/1438-4639-00254
    • Lacour M, Zunder T, Restle A, Schwarzer G (2004) No evidenceforanimpactofselenium supplementationonenvi-ronment associated health disorders-a systematic review. Int J Hyg Environ Health 207, 1-13. (Pubitemid 38082248)
    • (2004) International Journal of Hygiene and Environmental Health , vol.207 , Issue.1 , pp. 1-13
    • Lacour, M.1    Zunder, T.2    Restle, A.3    Schwarzer, G.4
  • 58
    • 77953561035 scopus 로고    scopus 로고
    • Treatment of Alzheimer's Disease with a Cholinesterase Inhibitor Combined with Antioxidants
    • Cornelli U (2010) Treatment of Alzheimer's Disease with a Cholinesterase Inhibitor Combined with Antioxidants. Neu-rodegenerative Dis 7, 193-202.
    • (2010) Neu-rodegenerative Dis , vol.7 , pp. 193-202
    • Cornelli, U.1
  • 59
    • 84961432203 scopus 로고
    • Dietary supplementation with zinc sulphate, sodium selenite and fatty acids in early dementia of Alzheimer's type
    • Van Rhijn AG, Prior CA, Corrigan FM (1990) Dietary supplementation with zinc sulphate, sodium selenite and fatty acids in early dementia of Alzheimer's type. J Nutr Med 1, 259-266.
    • (1990) J Nutr Med , vol.1 , pp. 259-266
    • Van Rhijn, A.G.1    Prior, C.A.2    Corrigan, F.M.3
  • 60
    • 0034837151 scopus 로고    scopus 로고
    • Effect of vitamin and trace-element supplementation on cognitive function in elderly subjects
    • DOI 10.1016/S0899-9007(01)00610-4, PII S0899900701006104
    • Chandra RK (2001) Effectofvitamin and trace-element supplementation on cognitive function in elderly subjects. Nutrition 17, 709-712. (Pubitemid 32821143)
    • (2001) Nutrition , vol.17 , Issue.9 , pp. 709-712
    • Chandra, R.K.1
  • 63
    • 35448935193 scopus 로고    scopus 로고
    • Effects of dietary supplements on depressive symptoms in older patients: A randomised double-blind placebo-controlled trial
    • DOI 10.1016/j.clnu.2007.06.007, PII S0261561407000994
    • Gariballa S, Forster S (2007) Effects of dietary supplements on depressive symptoms in older patients: a randomised double-blind placebo-controlled trial. Clin Nutr 26, 545-551. (Pubitemid 47618321)
    • (2007) Clinical Nutrition , vol.26 , Issue.5 , pp. 545-551
    • Gariballa, S.1    Forster, S.2
  • 64
    • 0021829630 scopus 로고
    • Vitamin e and selenium supplementation in geriatric patients
    • Tolonen M, Halme M, Sarna S (1985) Vitamin E and selenium supplementation in geriatric patients. Biol Trace Elem Res 7, 161-168.
    • (1985) Biol Trace Elem Res , vol.7 , pp. 161-168
    • Tolonen, M.1    Halme, M.2    Sarna, S.3
  • 65
    • 0033774075 scopus 로고    scopus 로고
    • Cognitive decline is associated with systemic oxida-tive stress: The EVA study
    • Berr C, Balansard B, Arnaud J, Roussel AM, Alperovitch A (2000) Cognitive decline is associated with systemic oxida-tive stress: the EVA study. J Am Geriatr Soc 48, 1285-1291.
    • (2000) J Am Geriatr Soc , vol.48 , pp. 1285-1291
    • Berr, C.1    Balansard, B.2    Arnaud, J.3    Roussel, A.M.4    Alperovitch, A.5
  • 66
    • 0032126730 scopus 로고    scopus 로고
    • Use of antioxidant supplements and its association with cognitive function in a rural elderly cohort: The movies project
    • Mendelsohn AB, Belle SH, Stoehr GP, Ganguli M (1998) Use of antioxidant supplements and its association with cognitive functioninarural elderly cohort: the MoVIES project. Am J Epidemiol 148, 38-44. (Pubitemid 28317543)
    • (1998) American Journal of Epidemiology , vol.148 , Issue.1 , pp. 38-44
    • Mendelsohn, A.B.1    Belle, S.H.2    Stoehr, G.P.3    Ganguli, M.4
  • 71
    • 1642271237 scopus 로고    scopus 로고
    • Enzymatic antioxidant balance and cognitive decline in aging - The EVA study
    • DOI 10.1023/B:EJEP.0000017830.27594.e9
    • Berr C, Richard MJ, Gourlet V, Garrel C, Favier A (2004) Enzymatic antioxidant balance and cognitive decline in aging-the EVA study. Eur J Epidemiol 19, 133-138. (Pubitemid 38374563)
    • (2004) European Journal of Epidemiology , vol.19 , Issue.2 , pp. 133-138
    • Berr, C.1    Richard, M.-J.2    Gourlet, V.3    Garrel, C.4    Favier, A.5
  • 76
    • 0031800225 scopus 로고    scopus 로고
    • Imbalances of trace elements related to oxidative damage in Alzheimer's disease brain
    • Cornett CR, Markesbery WR, Ehmann WD (1998) Imbalances of trace elements related to oxidative damage in Alzheimer's disease brain. Neurotoxicology 19, 339-345.
    • (1998) Neurotoxicology , vol.19 , pp. 339-345
    • Cornett, C.R.1    Markesbery, W.R.2    Ehmann, W.D.3
  • 79
    • 0022622788 scopus 로고
    • Brain trace elements in Alzheimer's disease
    • Ehmann WD, Markesbery WR, Alauddin M, Hossain TI, Brubaker EH (1986) Brain trace elements in Alzheimer's disease. Neurotoxicology 7, 197-206. (Pubitemid 16116632)
    • (1986) NeuroToxicology , vol.7 , Issue.1 , pp. 197-206
    • Ehmann, W.D.1    Markesbery, W.R.2    Alauddin, M.3
  • 80
    • 0026041595 scopus 로고
    • Metals and trace elements in plasma and cerebrospinal fluid in normal aging and Alzheimer's disease
    • Basun H, Forssell LG, Wetterberg L, Winblad B (1991) Metals and trace elements in plasma and cerebrospinal fluid in normal aging and Alzheimer's disease. J Neural Transm Park Dis Dement Sect 3, 231-258.
    • (1991) J Neural Transm Park Dis Dement Sect , vol.3 , pp. 231-258
    • Basun, H.1    Forssell, L.G.2    Wetterberg, L.3    Winblad, B.4
  • 82
    • 0022480830 scopus 로고
    • Increased glu-tathione peroxidase activity in erythrocytes in patients with Alzheimer's disease/senile dementia of Alzheimer's type
    • Annerén G, Gardner A, Lundin T (1986) Increased glu-tathione peroxidase activity in erythrocytes in patients with Alzheimer's disease/senile dementia of Alzheimer's type. Acta Neurol Scand 73, 586.
    • (1986) Acta Neurol Scand , vol.73 , pp. 586
    • Annerén, G.1    Gardner, A.2    Lundin, T.3
  • 83
    • 77953544297 scopus 로고    scopus 로고
    • Alter-ationsofplasma magnesium, copper, zinc, ironand selenium concentrations and some related erythrocyte antioxidant enzyme activities in patients with Alzheimer's disease
    • Vural H, Demirin H, Kara Y, Eren I, Delibas N (2010) Alter-ationsofplasma magnesium, copper, zinc, ironand selenium concentrations and some related erythrocyte antioxidant enzyme activities in patients with Alzheimer's disease. J Trace Elem Med Biol 24, 169-173.
    • (2010) J Trace Elem Med Biol , vol.24 , pp. 169-173
    • Vural, H.1    Demirin, H.2    Kara, Y.3    Eren, I.4    Delibas, N.5
  • 84
    • 46849101764 scopus 로고    scopus 로고
    • Metal concentrations in plasma and cerebrospinal fluid in patients with Alzheimer's disease
    • DOI 10.1159/000129365
    • Gerhardsson L, Lundh T, Minthon L, Londos E (2008) Metal concentrations in plasma and cerebrospinal fluid in patients with Alzheimer's disease. Dement Geriatr Cogn Disord 25, 508-515. (Pubitemid 351957413)
    • (2008) Dementia and Geriatric Cognitive Disorders , vol.25 , Issue.6 , pp. 508-515
    • Gerhardsson, L.1    Lundh, T.2    Minthon, L.3    Londos, E.4
  • 86
    • 0030917212 scopus 로고    scopus 로고
    • Elemental analysis of the frontal lobe of "normal" brain tissue and that affected by Alzheimer's disease
    • Stedman JD, Spyrou NM (1997) Elemental analysis of the frontal lobe of "normal" brain tissue and that affected by Alzheimer's disease. J Radioanal Nucl Chem 217, 163-166.
    • (1997) J Radioanal Nucl Chem , vol.217 , pp. 163-166
    • Stedman, J.D.1    Spyrou, N.M.2
  • 87
    • 0029871412 scopus 로고    scopus 로고
    • Peripheral antioxidant enzyme activities and selenium in elderly subjects and in dementia of Alzheimer's type - Place of the extracellular glutathione peroxidase
    • DOI 10.1016/0891-5849(95)02058-6
    • Ceballos-Picot I, Merad-Boudia M, Nicole A, Thevenin M, Hellier G, Legrain S, Berr C (1996) Peripheral antioxidant enzyme activities and selenium in elderly subjects and in dementia of Alzheimer's type-place of the extracellular glutathione peroxidase. Free Radic Biol Med 20, 579-587. (Pubitemid 26097275)
    • (1996) Free Radical Biology and Medicine , vol.20 , Issue.4 , pp. 579-587
    • Ceballos-Picot, I.1    Merad-Boudia, M.2    Nicole, A.3    Thevenin, M.4    Hellier, G.5    Legrain, S.6    Berr, C.7
  • 90
    • 72649096229 scopus 로고    scopus 로고
    • Changes of some oxidative stress markers in the serum of patients with mild cognitive impairment and Alzheimer's disease
    • Padurariu M, Ciobica A, Hritcu L, Stoica B, Bild W, Ste-fanescu C (2009) Changes of some oxidative stress markers in the serum of patients with mild cognitive impairment and Alzheimer's disease. Neurosci Lett 469, 6-10.
    • (2009) Neurosci Lett , vol.469 , pp. 6-10
    • Padurariu, M.1    Ciobica, A.2    Hritcu, L.3    Stoica, B.4    Bild, W.5    Ste-Fanescu, C.6
  • 91
    • 75949121583 scopus 로고    scopus 로고
    • Oxidative stress in the progression of Alzheimer disease in the frontal cortex
    • Ansari MA, Scheff SW (2010) Oxidative stress in the progression of Alzheimer disease in the frontal cortex. J Neuropathol Exp Neurol 69, 155-167.
    • (2010) J Neuropathol Exp Neurol , vol.69 , pp. 155-167
    • Ansari, M.A.1    Scheff, S.W.2
  • 92
    • 47049127899 scopus 로고    scopus 로고
    • Association between enzymatic and non-enzymatic antioxidant defense mechanism with apolipoproteinE genotypes in Alzheimer disease
    • Kharrazi H, Vaisi-Raygani A, Rahimi Z, Tavilani H, Aminian M, Pourmotabbed T (2008) Association between enzymatic and non-enzymatic antioxidant defense mechanism with apolipoproteinE genotypes in Alzheimer disease. Clin Biochem 41, 932-936.
    • (2008) Clin Biochem , vol.41 , pp. 932-936
    • Kharrazi, H.1    Vaisi-Raygani, A.2    Rahimi, Z.3    Tavilani, H.4    Aminian, M.5    Pourmotabbed, T.6
  • 93
    • 0035180964 scopus 로고    scopus 로고
    • Vitamins, trace elements, and antioxidant status in dementia disorders
    • Tabet N, Mantle D, Walker Z, Orrell M (2001) Vitamins, trace elements, and antioxidant status in dementia disorders. Int Psychogeriatr 13, 265.
    • (2001) Int Psychogeriatr , vol.13 , pp. 265
    • Tabet, N.1    Mantle, D.2    Walker, Z.3    Orrell, M.4
  • 96
    • 0345104375 scopus 로고    scopus 로고
    • Evidence against the involvement of reactive oxygen species in the pathogenesis of neuronal death in Down's syndrome and Alzheimer's disease
    • DOI 10.1016/0024-3205(96)00334-7
    • Hayn M, Kremser K, Singewald N, Cairns N, Nemethova M, Lubec B, Lubec G (1996) Evidence against the involvement of reactive oxygen species in the pathogenesis of neuronal death in Down's syndrome and Alzheimer's disease. Life Sci 59, 537-544. (Pubitemid 26274415)
    • (1996) Life Sciences , vol.59 , Issue.7 , pp. 537-544
    • Hayn, M.1    Kremser, K.2    Singewald, N.3    Cairns, N.4    Nemethova, M.5    Lubec, B.6    Lubec, G.7
  • 97
    • 0029073455 scopus 로고
    • Elevated thiobarbituric acid-reactive substances and antioxidant enzyme activity in the brain in Alzheimer's disease
    • Lovell MA, Ehmann WD, Butler SM, Markesbery WR (1995) Elevated thiobarbituric acid-reactive substances and antioxidant enzyme activity in the brain in Alzheimer's disease. Neurology 45, 1594-1601.
    • (1995) Neurology , vol.45 , pp. 1594-1601
    • Lovell, M.A.1    Ehmann, W.D.2    Butler, S.M.3    Markesbery, W.R.4
  • 99
    • 4544354817 scopus 로고    scopus 로고
    • Impact of gender on upregulation of antioxidant defence mechanisms in Alzheimer's disease brain
    • DOI 10.1007/s00702-004-0156-5
    • Schuessel K, Leutner S, Cairns NJ, Müller WE, Eckert A (2004) Impact of gender on upregulation of antioxidant defence mechanisms in Alzheimer's disease brain. J Neural Transm 111, 1167-1182. (Pubitemid 39222776)
    • (2004) Journal of Neural Transmission , vol.111 , Issue.9 , pp. 1167-1182
    • Schuessel, K.1    Leutner, S.2    Cairns, N.J.3    Muller, W.E.4    Eckert, A.5
  • 100
    • 0033969616 scopus 로고    scopus 로고
    • Decreased thioredoxin and increased thioredoxin reductase levels in Alzheimer's disease brain
    • DOI 10.1016/S0891-5849(99)00258-0, PII S0891584999002580
    • Lovell MA, Xie C, Gabbita SP, Markesbery WR (2000) Decreased thioredoxin and increased thioredoxin reductase levels in Alzheimer's disease brain. Free Radic Biol Med 28, 418-427. (Pubitemid 30110658)
    • (2000) Free Radical Biology and Medicine , vol.28 , Issue.3 , pp. 418-427
    • Lovell, M.A.1    Xie, C.2    Gabbita, S.P.3    Markesbery, W.R.4
  • 101
    • 0022665705 scopus 로고
    • Brain glutathione peroxidaseinneurodegenerative disorders
    • Kish SJ, Morito CL, Hornykiewicz O (1986) Brain glutathione peroxidaseinneurodegenerative disorders. Neu-rochem Pathol 4, 23-28.
    • (1986) Neu-rochem Pathol , vol.4 , pp. 23-28
    • Kish, S.J.1    Morito, C.L.2    Hornykiewicz, O.3
  • 102
    • 78349309643 scopus 로고    scopus 로고
    • Genetic polymorphisms in apolipoprotein e and glutathione peroxidase 1 genes in the Ecuadorian population affected with Alzheimer's disease
    • Paz-y-Miño C, Carrera C, López-Cortés A, Muñoz MJ, Cumbal N, Castro B, Cabrera A, Sánchez ME (2010) Genetic polymorphisms in apolipoprotein E and glutathione peroxidase 1 genes in the Ecuadorian population affected with Alzheimer's disease. Am J Med Sci 340, 373-377.
    • (2010) Am J Med Sci , vol.340 , pp. 373-377
    • Paz-Y-Miño, C.1    Carrera, C.2    López-Cortés, A.3    Muñoz, M.J.4    Cumbal, N.5    Castro, B.6    Cabrera, A.7    Sánchez, M.E.8
  • 105
    • 0028385744 scopus 로고
    • Regional brain activity of free radical defense enzymes in autopsy samples from patients with Alzheimer's disease and from nondemented controls
    • Chen L, Richardson JS, Caldwell JC, Ang LC (1994) Regional brain activity of free radical defense enzymes in autopsy samples from patients with Alzheimer's disease and from nondemented controls. Int JNeurosci 75, 83-90. (Pubitemid 2072086)
    • (1994) International Journal of Neuroscience , vol.75 , Issue.1-2 , pp. 83-90
    • Chen Lihua1    Richardson, J.S.2    Caldwell, J.E.3    Ang, L.C.4
  • 106
    • 0007289046 scopus 로고    scopus 로고
    • A comparative study in Alzheimer's and normal brains of trace element distribution using PIXE and INA analyses and glucose metabolism by positron emission tomography
    • Cutts DA, Maguire RP, Stedman JD, Leenders KL, Spy-rou NM (1999) A comparative study in Alzheimer's and normal brains of trace element distribution using PIXE and INA analyses and glucose metabolism by positron emission tomography. Biol Trace Elem Res 71, 541-549. (Pubitemid 30041488)
    • (1999) Biological Trace Element Research , vol.71-72 , pp. 541-549
    • Cutts, D.A.1    Maguire, R.P.2    Stedman, J.D.3    Leenders, K.L.4    Spyrou, N.M.5
  • 107
    • 17844377317 scopus 로고    scopus 로고
    • Higher fat and carbohydrate intake in dementia patients is associated with increased blood glutathione peroxidase activity
    • DOI 10.1017/S1041610205001006
    • Tabet N, Mantle D, Walker Z, Orrell M (2005) Higher fat and carbohydrate intake in dementia patients is associated with increased blood glutathione peroxidase activity. Int Psychogeriatr 17, 91-98. (Pubitemid 40593650)
    • (2005) International Psychogeriatrics , vol.17 , Issue.1 , pp. 91-98
    • Tabet, N.1    Mantle, D.2    Walker, Z.3    Orrell, M.4
  • 110
    • 3543106803 scopus 로고    scopus 로고
    • Relations between trace elements in drinking water and elderly residents' cognitive function
    • Liang C, Ji R, Cao J, Jiang Y, Yu B, Ma F, Wu Y, Ying B, Zhang Y (2003) Relations between trace elements in drinking water and elderly residents' cognitive function. J Hygiene Res 32, 436-440.
    • (2003) J Hygiene Res , vol.32 , pp. 436-440
    • Liang, C.1    Ji, R.2    Cao, J.3    Jiang, Y.4    Yu, B.5    Ma, F.6    Wu, Y.7    Ying, B.8    Zhang, Y.9
  • 112
    • 0020354509 scopus 로고
    • Glutathione peroxidase in human cerebrospinal fluid
    • DOI 10.1016/0006-8993(82)90409-7
    • Kaplan E, Bigelow D, Vatassery G, Ansari K (1982) Gluta-thione peroxidase in human cerebrospinal fluid. Brain Res 252, 391-393. (Pubitemid 13238959)
    • (1982) Brain Research , vol.252 , Issue.2 , pp. 391-393
    • Kaplan, E.1    Bigelow, D.2    Vatassery, G.3    Ansari, K.4
  • 113
    • 68349091417 scopus 로고    scopus 로고
    • Concentrations of metals, beta-amyloid and taumarkers in cerebrospinal fluid in patients with Alzheimer's disease
    • Gerhardsson L, Blennow K, Lundh T, Londos E, Minthon L (2009) Concentrations of metals, beta-amyloid and taumarkers in cerebrospinal fluid in patients with Alzheimer's disease. Dement Geriatr Cogn Disord 28, 88-94.
    • (2009) Dement Geriatr Cogn Disord , vol.28 , pp. 88-94
    • Gerhardsson, L.1    Blennow, K.2    Lundh, T.3    Londos, E.4    Minthon, L.5
  • 114
    • 0024506701 scopus 로고
    • Biochemical and clinical effects of an antioxidative supplementation of geriatric patients. A double blind study
    • Clausen J, Nielsen S, Kristensen M (1989) Biochemical and clinical effects of an antioxidative supplementation of geriatric patients. Biol Trace Elem Res 20, 135-151. (Pubitemid 19120173)
    • (1989) Biological Trace Element Research , vol.20 , Issue.1-2 , pp. 135-151
    • Clausen, J.1    Achim Nielsen, S.2    Kristensen, M.3
  • 116
    • 0023571213 scopus 로고
    • Neutron activation analysis techniques for identifying elemental status in Alzheimer's disease
    • Ward NI, Mason JA (1987) Neutron activation analysis techniques for identifying elemental status in Alzheimer's disease. J Radioanal Nucl Chem 113, 515-526. (Pubitemid 18053924)
    • (1987) Journal of Radioanalytical and Nuclear Chemistry , vol.113 , Issue.2 , pp. 515-526
    • Ward, N.I.1    Mason, J.A.2
  • 117
    • 0027669512 scopus 로고
    • Hippocampal tin, aluminum and zinc in Alzheimer's disease
    • Corrigan FM, Reynolds GP, Ward NI (1993) Hippocampal tin, aluminum and zinc in Alzheimer's disease. Bio Metals 6, 149-154.
    • (1993) Bio Metals , vol.6 , pp. 149-154
    • Corrigan, F.M.1    Reynolds, G.P.2    Ward, N.I.3
  • 119
    • 77952294953 scopus 로고    scopus 로고
    • Neuronal selenoprotein expression is required for interneuron development and prevents seizuresand neurodegeneration
    • Wirth EK, Conrad M, Winterer J, Wozny C, Carlson BA, Roth S, Schmitz D, Bornkamm GW, Coppola V, Tessarollo L, Schomburg L, Köhrle J, Hatfield DL, Schweizer U (2010) Neuronal selenoprotein expression is required for interneuron development and prevents seizuresand neurodegeneration. FASEB J 24, 844-852.
    • (2010) FASEB J , vol.24 , pp. 844-852
    • Wirth Ek, C.1
  • 121
    • 67649552785 scopus 로고    scopus 로고
    • ERK activation induced by selenium treatment significantly downregulates beta/gamma-secretase activity and Tau phosphorylation in the transgenic rat overexpressing human selenoprotein M
    • Yim SY, Chae KR, Shim SB, Hong JT, Park JY, Lee CY, Son HJ, Sheen YY, Hwang DY (2009) ERK activation induced by selenium treatment significantly downregulates beta/gamma-secretase activity and Tau phosphorylation in the transgenic rat overexpressing human selenoprotein M. Int J Mol Med 24, 91-96.
    • (2009) Int J Mol Med , vol.24 , pp. 91-96
    • Yim, S.Y.1    Chae, K.R.2    Shim, S.B.3    Hong, J.T.4    Park, J.Y.5    Lee, C.Y.6    Son, H.J.7    Sheen, Y.Y.8    Hwang, D.Y.9
  • 122
    • 67349196022 scopus 로고    scopus 로고
    • Organoselenium (Sel-Plex diet) decreases amyloid burden and RNA and DNA oxidative damage in APP/PS1 mice
    • Lovell MA, Xiong S, Lyubartseva G, Markesbery WR (2009) Organoselenium (Sel-Plex diet) decreases amyloid burden and RNA and DNA oxidative damage in APP/PS1 mice. Free Radic Biol Med 46, 1527-1533.
    • (2009) Free Radic Biol Med , vol.46 , pp. 1527-1533
    • Lovell, M.A.1    Xiong, S.2    Lyubartseva, G.3    Markesbery, W.R.4
  • 123
    • 45249108210 scopus 로고    scopus 로고
    • Sodium selenite inhibits gamma-secretase activity through activation of ERK
    • Tung Y, Hsu W, Wang B, Wu S, Yen C, Hu M, Liao Y (2008) Sodium selenite inhibits gamma-secretase activity through activation of ERK. Neurosci Lett 440, 38-43.
    • (2008) Neurosci Lett , vol.440 , pp. 38-43
    • Tung, Y.1    Hsu, W.2    Wang, B.3    Wu, S.4    Yen, C.5    Hu, M.6    Liao, Y.7
  • 124
    • 37549060636 scopus 로고    scopus 로고
    • Neurodegeneration in mice resulting from loss of functional selenoprotein P or its receptor apolipoprotein e receptor 2
    • Valentine WM, Abel TW, Hill KE, Austin LM, Burk RF (2008) Neurodegeneration in mice resulting from loss of functional selenoprotein P or its receptor apolipoprotein E receptor 2. J Neuropathol Exp Neurol 67, 68-77.
    • (2008) J Neuropathol Exp Neurol , vol.67 , pp. 68-77
    • Valentine, W.M.1    Abel, T.W.2    Hill, K.E.3    Austin, L.M.4    Burk, R.F.5
  • 128
    • 76949083466 scopus 로고    scopus 로고
    • Organoselenium improves memory decline in mice: Involvement of acetylcholinesterase activity
    • Pinton S, da Rocha JT, Zeni G, Nogueira CW (2010) Organoselenium improves memory decline in mice: involvement of acetylcholinesterase activity. Neurosci Lett 472, 56-60.
    • (2010) Neurosci Lett , vol.472 , pp. 56-60
    • Pinton, S.1    Da Rocha, J.T.2    Zeni, G.3    Nogueira, C.W.4
  • 129
    • 77956385203 scopus 로고    scopus 로고
    • Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models
    • van Eersel J, Ke YD, Liu X, Delerue F, Kril JJ, Götz J, Ittner LM (2010) Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models. Proc Natl Acad Sci USA 107, 13888-13893.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 13888-13893
    • Van Eersel, J.1    Ke, Y.D.2    Liu, X.3    Delerue, F.4    Kril, J.J.5    Götz, J.6    Ittner, L.M.7
  • 130
    • 77950634408 scopus 로고    scopus 로고
    • Methionine-oxidized amyloid fibrils are poor substrates for human methionine sulfoxide reductases A and B2
    • Binger KJ, Griffin MD, Heinemann SH, Howlett GJ (2010) Methionine-oxidized amyloid fibrils are poor substrates for human methionine sulfoxide reductases A and B2. Biochemistry 49, 2981-2983.
    • (2010) Biochemistry , vol.49 , pp. 2981-2983
    • Binger, K.J.1    Griffin, M.D.2    Heinemann, S.H.3    Howlett, G.J.4
  • 131
    • 77249086074 scopus 로고    scopus 로고
    • Oxidation of methionine 35 reduces toxicity of the amyloid beta-peptide (1-42) in neuroblastoma cells (IMR-32) via enzyme methionine sulfoxide reductase A expression and function
    • Misiti F, Clementi ME, Giardina B (2010) Oxidation of methionine 35 reduces toxicity of the amyloid beta-peptide (1-42) in neuroblastoma cells (IMR-32) via enzyme methionine sulfoxide reductase A expression and function. Neurochem Int 56, 597-602.
    • (2010) Neurochem Int , vol.56 , pp. 597-602
    • Misiti, F.1    Clementi, M.E.2    Giardina, B.3
  • 132
    • 33745779644 scopus 로고    scopus 로고
    • Glutathione peroxidase 4 protects cortical neurons from oxidative injury and amyloid toxicity
    • DOI 10.1002/jnr.20868
    • Ran Q, Gu M, Van Remmen H, Strong R, Roberts JL, Richardson A (2006) Glutathione peroxidase 4 protects cortical neurons from oxidative injury and amyloid toxicity. J Neurosci Res 84, 202-208. (Pubitemid 44023075)
    • (2006) Journal of Neuroscience Research , vol.84 , Issue.1 , pp. 202-208
    • Ran, Q.1    Gu, M.2    Van Remmen, H.3    Strong, R.4    Roberts, J.L.5    Richardson, A.6
  • 133
    • 33751542983 scopus 로고    scopus 로고
    • Selenazoles (selenium compounds) facilitate survival of cultured rat pheochromocytoma PC12 cells after serum-deprivation and stimulate their neuronal differentiation via activation of Akt and mitogen-activated protein kinase, respectively
    • DOI 10.1016/j.bbrc.2006.11.025, PII S0006291X06024855
    • Nishina A, Sekiguchi A, Fukumoto RH, Koketsu M, Furukawa S (2007) Selenazoles (selenium compounds) facilitate survival of cultured rat pheochromocytoma PC12 cells after serum-deprivation and stimulate their neuronal differentiation via activation of Akt and mitogen-activated protein kinase, respectively. Biochem Biophys Res Commun 352, 360-365. (Pubitemid 44838496)
    • (2007) Biochemical and Biophysical Research Communications , vol.352 , Issue.2 , pp. 360-365
    • Nishina, A.1    Sekiguchi, A.2    Fukumoto, R.-h.3    Koketsu, M.4    Furukawa, S.5
  • 134
    • 4644285299 scopus 로고    scopus 로고
    • Antioxidant effect of vitamin E and selenium on lipid peroxidation, enzyme activities and biochemical parameters in rats exposed to aluminium
    • DOI 10.1016/j.jtemb.2004.04.001
    • El-Demerdash FM (2004) Antioxidant effect of vitamin E and selenium on lipid peroxidation, enzyme activities and biochemical parameters in rats exposed to aluminium. J Trace Elem Med Biol 18, 113-121. (Pubitemid 39285971)
    • (2004) Journal of Trace Elements in Medicine and Biology , vol.18 , Issue.1 , pp. 113-121
    • El-Demerdash, F.M.1
  • 135
    • 27644478606 scopus 로고    scopus 로고
    • Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation
    • DOI 10.1111/j.1460-9568.2005.04391.x
    • Liu F, Grundke-Iqbal I, Iqbal K, Gong CX (2005) Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation. Eur J Neurosci 22, 1942-1950. (Pubitemid 41579384)
    • (2005) European Journal of Neuroscience , vol.22 , Issue.8 , pp. 1942-1950
    • Liu, F.1    Grundke-Iqbal, I.2    Iqbal, K.3    Gong, C.-X.4
  • 136
    • 34250880256 scopus 로고    scopus 로고
    • Elevated levels of brain-pathologies associated with neurodegenerative diseases in the methionine sulfoxide reductase a knockout mouse
    • DOI 10.1007/s00221-007-0903-6
    • Pal R, Oien DB, Ersen FY, Moskovitz J (2007) Elevated levels of brain-pathologies associated with neurodegenerative diseases in the methionine sulfoxide reductase A knockout mouse. Exp Brain Res 180, 765-774. (Pubitemid 46988121)
    • (2007) Experimental Brain Research , vol.180 , Issue.4 , pp. 765-774
    • Pal, R.1    Oien, D.B.2    Ersen, F.Y.3    Moskovitz, J.4
  • 137
    • 33646369421 scopus 로고    scopus 로고
    • Lack of glutathione peroxidase-1 exacerbates Aβ-mediated neurotoxicity in cortical neurons
    • DOI 10.1007/s00702-005-0352-y
    • Crack PJ, Cimdins K, Ali U, Hertzog PJ, Iannello RC (2006) Lack of glutathione peroxidase-1 exacerbates Aβ-mediated neurotoxicity in cortical neurons. J Neural Transm 113, 645-657. (Pubitemid 43673604)
    • (2006) Journal of Neural Transmission , vol.113 , Issue.5 , pp. 645-657
    • Crack, P.J.1    Cimdins, K.2    Ali, U.3    Hertzog, P.J.4    Iannello, R.C.5
  • 138
    • 0347986900 scopus 로고    scopus 로고
    • Neurological dysfunction occurs in mice with targeted deletion of the selenoprotein P gene
    • Hill KE, Zhou J, McMahan WJ, Motley AK, Burk RF (2004) Neurological dysfunction occurs in mice with targeted deletion of the selenoprotein P gene. J Nutr 134, 157-161. (Pubitemid 38057440)
    • (2004) Journal of Nutrition , vol.134 , Issue.1 , pp. 157-161
    • Hill, K.E.1    Zhou, J.2    McMahan, W.J.3    Motley, A.K.4    Burk, R.F.5
  • 139
    • 2342486214 scopus 로고    scopus 로고
    • Increased viability of PC12 cells exposed to amyloid-beta peptide by transduction with human TAT-methionine sulfoxide reductase
    • Jung B, Lee EH, Chung WS, Lee SJ, Shin SH, Joo SH, Kim SK, Lee JH (2003) Increased viability of PC12 cells exposed to amyloid-beta peptide by transduction with human TAT-methionine sulfoxide reductase. Neuroreport 14, 2349-2353.
    • (2003) Neuroreport , vol.14 , pp. 2349-2353
    • Jung, B.1    Lee, E.H.2    Chung, W.S.3    Lee, S.J.4    Shin, S.H.5    Joo, S.H.6    Kim, S.K.7    Lee, J.H.8
  • 140
    • 0032941728 scopus 로고    scopus 로고
    • Regional expression of the type 3 iodothyronine deiodinase messenger ribonucleic acid in the rat central nervous system and its regulation by thyroid hormone
    • DOI 10.1210/en.140.2.784
    • Tu HM, Legradi G, Bartha T, Salvatore D, Lechan RM, Larsen PR (1999) Regional expression of the type 3 iodothy-ronine deiodinase messenger ribonucleic acid in the rat central nervous system and its regulation by thyroid hormone. Endocrinology 140, 784-790. (Pubitemid 29058213)
    • (1999) Endocrinology , vol.140 , Issue.2 , pp. 784-790
    • Tu, H.M.1    Legradi, G.2    Bartha, T.3    Salvatore, D.4    Lechan, R.M.5    Larsen, P.R.6
  • 141
    • 77955484192 scopus 로고    scopus 로고
    • Role of selenoprotein P in Alzheimer's disease
    • Takemoto AS, Berry MJ, Bellinger FP (2010) Role of Selenoprotein P in Alzheimer's Disease. Ethn Dis 20, S1 92-95.
    • (2010) Ethn Dis , vol.20 S , Issue.1 , pp. 92-95
    • Takemoto, A.S.1    Berry, M.J.2    Bellinger, F.P.3
  • 143
    • 59649103113 scopus 로고    scopus 로고
    • Mechanisms of inhibition of zinc-finger transcription factors by selenium compounds ebselen and selenite
    • Larabee JL, Hocker JR, Hanas JS (2009) Mechanisms of inhibition of zinc-finger transcription factors by selenium compounds ebselen and selenite. J Inorg Biochem 103, 419-426.
    • (2009) J Inorg Biochem , vol.103 , pp. 419-426
    • Larabee, J.L.1    Hocker, J.R.2    Hanas, J.S.3
  • 144
    • 33847204338 scopus 로고    scopus 로고
    • Seleno-L-methionine protects against beta-amyloid and iron/hydrogen oeroxide-mediated neuron death
    • Xiong S, Markesbery WR, Shao C, Lovell MA (2007) Seleno-L-methionine protects against beta-amyloid and iron/hydrogen oeroxide-mediated neuron death. Antioxid Redox Signal 9, 457-467.
    • (2007) Antioxid Redox Signal , vol.9 , pp. 457-467
    • Xiong, S.1    Markesbery, W.R.2    Shao, C.3    Lovell, M.A.4
  • 145
    • 33644841436 scopus 로고    scopus 로고
    • Selenomethionine prevents degeneration induced by overexpression of wild-type human α-synuclein during differentiation of neuroblastoma cells
    • Kumar B, Nahreini P, Hanson AJ, Andreatta C, Prasad JE, Prasad KN (2005) Selenomethionine prevents degeneration induced by overexpression of wild-type human alpha-synuclein during differentiation of neuroblastoma cells. J Am Coll Nutr 24, 516-523. (Pubitemid 43373177)
    • (2005) Journal of the American College of Nutrition , vol.24 , Issue.6 , pp. 516-523
    • Kumar, B.1    Nahreini, P.2    Hanson, A.J.3    Andreatta, C.4    Prasad, J.E.5    Prasad, K.N.6
  • 147
    • 84983725597 scopus 로고    scopus 로고
    • Ebselen prevents excitotoxicity provoked by glutamate in rat cerebellar granule neurons
    • DOI 10.1016/S0304-3940(01)01519-1, PII S0304394001015191
    • Porciúncula LO, Rocha JB, Boeck CR, Vendite D, Souza DO (2001) Ebselen prevents excitotoxicity provoked by gluta-mate in rat cerebellar granule neurons. Neurosci Lett 299, 217-220. (Pubitemid 32124850)
    • (2001) Neuroscience Letters , vol.299 , Issue.3 , pp. 217-220
    • Porciuncula, L.O.1    Rocha, J.B.T.2    Boeck, C.R.3    Vendite, D.4    Souza, D.O.5
  • 148
    • 0031770868 scopus 로고    scopus 로고
    • Biological interaction between transition metals (Ag, Cd and Hg), selenide/sulfide and selenoprotein P
    • DOI 10.1016/S0162-0134(98)10048-X, PII S016201349810048X
    • Sasakura C, Suzuki KT (1998) Biological interaction between transition metals (Ag, Cd and Hg), selenide/sulfide and selenoprotein P. J Inorg Biochem 71, 159-162. (Pubitemid 28531535)
    • (1998) Journal of Inorganic Biochemistry , vol.71 , Issue.3-4 , pp. 159-162
    • Sasakura, C.1    Suzuki, K.T.2
  • 149
    • 80052862644 scopus 로고    scopus 로고
    • Selenium status is associated with mood states and cognitive function in Chinese men
    • Penland JG (2006) Selenium status is associated with mood states and cognitive function in Chinese men. FASEB J 20, A1070.
    • (2006) FASEB J , vol.20
    • Penland, J.G.1
  • 151
    • 1842427909 scopus 로고    scopus 로고
    • 1 (a naturally occuring, proline-rich, polypeptide mixture) in the treatment of Alzheimer's disease
    • Bilikiewicz A, Gaus W (2004) Colostrinin (a naturally occurring, proline-rich, polypeptide mixture) in the treatment of Alzheimer's disease. J Alzheimers Dis 6, 17-26. (Pubitemid 38418554)
    • (2004) Journal of Alzheimer's Disease , vol.6 , Issue.1 , pp. 17-26
    • Bilikiewicz, A.1    Gaus, W.2
  • 157
    • 0014108436 scopus 로고
    • Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase
    • Paglia DE, Valentine WN (1967) Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med 70, 158-169.
    • (1967) J Lab Clin Med , vol.70 , pp. 158-169
    • Paglia, D.E.1    Valentine, W.N.2
  • 158
    • 0020621878 scopus 로고
    • Variation in the activities of glutathione peroxidase and superoxide dismutase and in the concentration of copper in the blood in various breed crosses of sheep
    • Woolliams JA, Wiener G, Anderson PH, McMurray CH (1983) Variation in the activities of glutathione peroxidase and superoxide dismutase and in the concentration of copper in the blood in various breed crosses of sheep. Res Vet Sci 34, 253-256. (Pubitemid 13070011)
    • (1983) Research in Veterinary Science , vol.34 , Issue.3 , pp. 253-256
    • Wooliams, J.A.1    Wiener, G.2    Anderson, P.H.3    McMurray, C.H.4
  • 159
    • 0020966833 scopus 로고
    • Selenium-dependent and non-selenium-dependent glutathione peroxidases in human tissue extracts
    • Carmagnol F, Sinet PM, Jerome H (1983) Selenium-dependent and non-selenium-dependent glutathione perox-idases in human tissue extracts. Biochim Biophys Acta 759, 49-57. (Pubitemid 13013120)
    • (1983) Biochimica et Biophysica Acta - General Subjects , vol.759 , Issue.1-2 , pp. 49-57
    • Carmagnol, F.1    Sinet, P.M.2    Jerome, H.3
  • 160
    • 0021288821 scopus 로고
    • Assays of glutathione peroxi-dase
    • Flohe L, Günzler WA (1984) Assays of glutathione peroxi-dase. Methods Enzymol 105, 114-121.
    • (1984) Methods Enzymol , vol.105 , pp. 114-121
    • Flohe, L.1    Günzler, W.A.2
  • 161
  • 162
    • 0032823578 scopus 로고    scopus 로고
    • Decrease in peptide methionine sulfoxide reductase in Alzheimer's disease brain
    • DOI 10.1046/j.1471-4159.1999.0731660.x
    • Gabbita SP, Aksenov MY, Lovell MA, Markesbery WR (1999) Decrease in peptide methionine sulfoxide reductase in Alzheimer's disease brain. J Neurochem 73, 1660-1666. (Pubitemid 29440169)
    • (1999) Journal of Neurochemistry , vol.73 , Issue.4 , pp. 1660-1666
    • Gabbita, S.P.1    Aksenov, M.Y.2    Lovell, M.A.3    Markesbery, W.R.4
  • 164
    • 0036084541 scopus 로고    scopus 로고
    • Antioxidant strategies for Alzheimer's disease
    • Grundman M, Delaney P (2009) Antioxidant strategies for Alzheimer's disease. Proc Nutr Soc 61, 191-202.
    • (2009) Proc Nutr Soc , vol.61 , pp. 191-202
    • Grundman, M.1    Delaney, P.2
  • 165
    • 0034796353 scopus 로고    scopus 로고
    • Role of free radicals in the neurodegenerative diseases: Therapeutic implications for antioxidant treatment
    • Halliwell B (2001) Role of free radicals in the neurode-generative diseases: therapeutic implications for antioxidant treatment. Drugs Aging 18, 685-716. (Pubitemid 32948277)
    • (2001) Drugs and Aging , vol.18 , Issue.9 , pp. 685-716
    • Halliwell, B.1
  • 166
    • 84996120592 scopus 로고
    • Oxidants and the central nervous system: Some fundamental questions. Is oxidant damage relevant to Parkinson's disease, Alzheimer's disease, traumatic injury or stroke?
    • Halliwell B (1989) Oxidants and the central nervous system: some fundamental questions. Is oxidant damage relevant to Parkinson's disease, Alzheimer's disease, traumatic injury or stroke? Acta Neurol Scand 80, 23-33. (Pubitemid 20022073)
    • (1989) Acta Neurologica Scandinavica, Supplement , vol.80 , Issue.126 , pp. 23-33
    • Halliwell, B.1
  • 167
    • 33744935554 scopus 로고    scopus 로고
    • Increased levels of 4-hydroxynonenal and acrolein, neurotoxic markers of lipid peroxidation, in the brain in Mild Cognitive Impairment and early Alzheimer's disease
    • DOI 10.1016/j.neurobiolaging.2005.06.004, PII S0197458005001740
    • Williams TI, Lynn BC, Markesbery WR, Lovell MA (2006) Increased levels of 4-hydroxynonenal and acrolein, neuro-toxic markers of lipid peroxidation, in the brain in Mild Cognitive Impairment and early Alzheimer's disease. Neu-robiol Aging 27, 1094-1099. (Pubitemid 43850642)
    • (2006) Neurobiology of Aging , vol.27 , Issue.8 , pp. 1094-1099
    • Williams, T.I.1    Lynn, B.C.2    Markesbery, W.R.3    Lovell, M.A.4
  • 168
  • 169
    • 33644987632 scopus 로고    scopus 로고
    • Elevated protein-bound levels of the lipid peroxidation product, 4-hydroxy-2-nonenal, in brain from persons with mild cognitive impairment
    • Butterfield DA, Reed T, Perluigi M, De Marco C, Coccia R, Cini C, Sultana R (2006) Elevated protein-bound levels of the lipid peroxidation product, 4-hydroxy-2-nonenal, in brain from persons with mild cognitive impairment. Neu-rosci Lett 397, 170-173.
    • (2006) Neu-rosci Lett , vol.397 , pp. 170-173
    • Butterfield, D.A.1    Reed, T.2    Perluigi, M.3    De Marco, C.4    Coccia, R.5    Cini, C.6    Sultana, R.7
  • 170
    • 0043172469 scopus 로고    scopus 로고
    • 4-Hydroxynonenal as a bioactive marker of pathophysiological processes
    • DOI 10.1016/S0098-2997(03)00023-2
    • Zarkovic N (2003) 4-Hydroxynonenal as a bioactive marker of pathophysiological processes. Mol Aspects Med 24, 281-291. (Pubitemid 36945028)
    • (2003) Molecular Aspects of Medicine , vol.24 , Issue.4-5 , pp. 281-291
    • Zarkovic, N.1
  • 171
    • 0031020476 scopus 로고    scopus 로고
    • A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid β- peptide
    • Mark RJ, Lovell MA, Markesbery WR, Uchida K, Matt-son MP (1997) A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion home-ostasis and neuronal death inducedbyamyloid beta-peptide. J Neurochem 68, 255-264. (Pubitemid 26427315)
    • (1997) Journal of Neurochemistry , vol.68 , Issue.1 , pp. 255-264
    • Mark, R.J.1    Lovell, M.A.2    Markesbery, W.R.3    Uchida, K.4    Mattson, M.P.5
  • 173
    • 0035943345 scopus 로고    scopus 로고
    • A portrait of Alzheimer secretases - New features and familiar faces
    • DOI 10.1126/science.1064638
    • Esler WP, Wolfe MS (2001) A portrait of Alzheimer sec-retases-new features and familiar faces. Science 293, 1449-1454. (Pubitemid 32801541)
    • (2001) Science , vol.293 , Issue.5534 , pp. 1449-1454
    • Esler, W.P.1    Wolfe, M.S.2
  • 174
    • 15944378214 scopus 로고    scopus 로고
    • Beta-Secretase. APP and Abeta in Alzheimer's disease
    • Vassar R (2005) beta-Secretase, APP and Abeta in Alzheimer's disease. Subcell Biochem 38, 79-103.
    • (2005) Subcell Biochem , vol.38 , pp. 79-103
    • Vassar, R.1
  • 175
    • 28544431728 scopus 로고    scopus 로고
    • 4-Hydroxynonenal disrupts zinc export in primary rat cortical cells
    • DOI 10.1016/j.neuro.2005.05.009, PII S0161813X05000926
    • Smith JL, Xiong S, Lovell MA (2006) 4-Hydroxynonenal disrupts zinc export in primary rat cortical cells. Neurotoxi-cology 27, 1-5. (Pubitemid 41745002)
    • (2006) NeuroToxicology , vol.27 , Issue.1 , pp. 1-5
    • Smith, J.L.1    Xiong, S.2    Lovell, M.A.3
  • 177
    • 34250167926 scopus 로고    scopus 로고
    • Effects of inorganic selenium compounds on oxidative DNA damage
    • DOI 10.1016/j.jinorgbio.2007.03.016, PII S0162013407000670
    • Ramoutar RR, Brumaghim JL (2007) Effects of inorganic selenium compounds on oxidative DNA damage. J Inorg Biochem 101, 1028-1035. (Pubitemid 46899203)
    • (2007) Journal of Inorganic Biochemistry , vol.101 , Issue.7 , pp. 1028-1035
    • Ramoutar, R.R.1    Brumaghim, J.L.2
  • 178
    • 31644432580 scopus 로고    scopus 로고
    • The central role of metal coordination in selenium antioxidant activity
    • Battin EE, Perron NR, Brumaghim JL (2006) The central role of metal coordination in selenium antioxidant activity. Inorg Chem 45, 499-501.
    • (2006) Inorg Chem , vol.45 , pp. 499-501
    • Battin, E.E.1    Perron, N.R.2    Brumaghim, J.L.3
  • 179
    • 67449102459 scopus 로고    scopus 로고
    • Antioxidant activity of sulfur and selenium: A review of reactive oxygen species scavenging, glutathione peroxidase, and metal-binding antioxidant mechanisms
    • Battin EE, Brumaghim JL (2009) Antioxidant activity of sulfur and selenium: a review of reactive oxygen species scavenging, glutathione peroxidase, and metal-binding antioxidant mechanisms. Cell Biochem Biophys 55, 1-23.
    • (2009) Cell Biochem Biophys , vol.55 , pp. 1-23
    • Battin, E.E.1    Brumaghim, J.L.2
  • 180
    • 0016651634 scopus 로고
    • Correlation between selenium and mercury in man following exposure to inorganic mercury
    • Kosta L, Byrne AR, Zelenko V (1975) Correlation between selenium and mercury in man following exposure to inorganic mercury. Nature 254, 238-239.
    • (1975) Nature , vol.254 , pp. 238-239
    • Kosta, L.1    Byrne, A.R.2    Zelenko, V.3
  • 181
    • 0037656518 scopus 로고    scopus 로고
    • Role of copper, zinc, selenium and tellurium in the cellular defense against oxidative and nitrosative stress
    • Klotz LO, KrönckeKD, Buchczyk DP, Sies H (2003) Role of copper, zinc, selenium and tellurium in the cellular defense against oxidative and nitrosative stress. J Nutr 133, 1448S.
    • (2003) J Nutr , vol.133
    • Klotz, L.O.1    Krönckekd Buchczyk, D.P.2    Sies, H.3
  • 182
    • 24044514005 scopus 로고    scopus 로고
    • Selenium, oxidative stress, and health aspects
    • DOI 10.1016/j.mam.2005.07.004, PII S0098299705000397
    • Brenneisen P, Steinbrenner H, Sies H (2005) Selenium, oxidative stress, and health aspects. Mol Aspects Med 26, 256-267. (Pubitemid 41225352)
    • (2005) Molecular Aspects of Medicine , vol.26 , Issue.4-5 SPEC. ISS. , pp. 256-267
    • Brenneisen, P.1    Steinbrenner, H.2    Sies, H.3
  • 183
    • 23944498579 scopus 로고    scopus 로고
    • Selenoprotein P: An extracellular protein with unique physical characteristics and a role in selenium homeostasis
    • DOI 10.1146/annurev.nutr.24.012003.132120
    • Burk RF, Hill KE (2005) Selenoprotein P: an extracellular protein with unique physical characteristics and a role in selenium homeostasis. Annu Rev Nutr 25, 215-235. (Pubitemid 41209001)
    • (2005) Annual Review of Nutrition , vol.25 , pp. 215-235
    • Burk, R.F.1    Hill, K.E.2
  • 184
    • 34547623184 scopus 로고    scopus 로고
    • The selenoproteome exhibits widely varying, tissue-specific dependence on selenoprotein P for selenium supply
    • DOI 10.1093/nar/gkm355
    • Hoffmann PR, Höge SC, Li PA, Hoffmann FW, Hashimoto AC, Berry MJ (2007) The selenoproteome exhibits widely varying, tissue-specific dependence on selenoprotein P for selenium supply. Nucleic Acids Res 35, 3963-3973. (Pubitemid 47244618)
    • (2007) Nucleic Acids Research , vol.35 , Issue.12 , pp. 3963-3973
    • Hoffmann, P.R.1    Hoge, S.C.2    Li, P.-A.3    Hoffmann, F.W.4    Hashimoto, A.C.5    Berry, M.J.6
  • 185
    • 33646067098 scopus 로고    scopus 로고
    • Involvement of selenoprotein P in protection of human astrocytes from oxidative damage
    • Steinbrenner H, Alili L, Bilgic E, Sies H, Brenneisen P (2006) Involvement of selenoprotein P in protection of human astrocytes from oxidative damage. Free Radical Biol Med 40, 1513-1523.
    • (2006) Free Radical Biol Med , vol.40 , pp. 1513-1523
    • Steinbrenner, H.1    Alili, L.2    Bilgic, E.3    Sies, H.4    Brenneisen, P.5
  • 186
    • 3042631024 scopus 로고    scopus 로고
    • Gene regulation and DNA damage in the ageing human brain
    • DOI 10.1038/nature02661
    • Lu T, Pan Y, Kao SY, Li C, Kohane I, Chan J, Yankner BA (2004) Gene regulation and DNA damage in the ageing human brain. Nature 429, 883-891. (Pubitemid 38843301)
    • (2004) Nature , vol.429 , Issue.6994 , pp. 883-891
    • Lu, T.1    Pan, Y.2    Kao, S.-Y.3    Li, C.4    Kohane, I.5    Chan, J.6    Yankner, B.A.7
  • 187
    • 34249729915 scopus 로고    scopus 로고
    • The selenium-rich C-terminal domain of mouse selenoprotein P is necessary for the supply of selenium to brain and testis but not for the maintenance of whole body selenium
    • DOI 10.1074/jbc.M700436200
    • Hill KE, Zhou J, Austin LM, Motley AK, Ham AJ, Olson GE, Atkins JF, Gesteland RF, Burk RF (2007) The selenium-rich C-terminal domain of mouse selenoprotein P is necessary for the supply of selenium to brain and testis but not for the maintenance of whole body selenium. J Biol Chem 282, 10972-10980. (Pubitemid 47100771)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.15 , pp. 10972-10980
    • Hill, K.E.1    Zhou, J.2    Austin, L.M.3    Motley, A.K.4    Ham, A.-J.L.5    Olson, G.E.6    Atkins, J.F.7    Gesteland, R.F.8    Burk, R.F.9
  • 188
    • 4344604663 scopus 로고    scopus 로고
    • Selenium and selenoproteins in mammals: Extraordinary, essential, enigmatic
    • Schomburg L, Schweizer U, Köhrle J (2004) Selenium and selenoproteins in mammals: extraordinary, essential, enigmatic. Cell Mol Life Sci 61, 1988-1995. (Pubitemid 39149889)
    • (2004) Cellular and Molecular Life Sciences , vol.61 , Issue.16 , pp. 1988-1995
    • Schomburg, L.1    Schweizer, U.2    Kohrle, J.3
  • 189
    • 0036170524 scopus 로고    scopus 로고
    • Mammalian selenoprotein in which selenocysteine (Sec) incorporation is supported by a new form of Sec insertion sequence element
    • DOI 10.1128/MCB.22.5.1402-1411.2002
    • Korotkov KV, Novoselov SV, Hatfield DL, Gladyshev VN (2002) Mammalian selenoprotein in which selenocysteine (Sec) incorporation is supported by a new form of Sec insertion sequence element. Mol Cell Biol 22, 1402-1411. (Pubitemid 34150777)
    • (2002) Molecular and Cellular Biology , vol.22 , Issue.5 , pp. 1402-1411
    • Korotkov, K.V.1    Novoselov, S.V.2    Hatfield, D.L.3    Gladyshev, V.N.4
  • 190
    • 77649242103 scopus 로고    scopus 로고
    • The neuropro-tective functions of selenoprotein M and its role in cytosolic calcium regulation
    • Reeves MA, Bellinger FP, Berry MJ (2010) The neuropro-tective functions of selenoprotein M and its role in cytosolic calcium regulation. Antioxid Redox Signal 12, 812-818.
    • (2010) Antioxid Redox Signal , vol.12 , pp. 812-818
    • Reeves, M.A.1    Bellinger, F.P.2    Berry, M.J.3
  • 192
    • 33847038020 scopus 로고    scopus 로고
    • Overexpression of selenoprotein H reduces Ht22 neuronal cell death after UVB irradiation by preventing superoxide formation
    • Ben Jilani KE, Panee J, He Q, Berry MJ, Li PA (2007) Overexpression of selenoprotein H reduces Ht22 neuronal cell death after UVB irradiation by preventing superoxide formation. Int J Biol Sci 3, 198-204.
    • (2007) Int J Biol Sci , vol.3 , pp. 198-204
    • Ben Jilani, K.E.1    Panee, J.2    He, Q.3    Berry, M.J.4    Li, P.A.5
  • 193
    • 0037165648 scopus 로고    scopus 로고
    • Selenoprotein W is a glutathione-dependent antioxidant in vivo
    • DOI 10.1016/S0014-5793(02)02628-5, PII S0014579302026285
    • Jeong D, Kim TS, Chung YW, Lee BJ, Kim IY (2002) Selenoprotein W is a glutathione-dependent antioxidant in vivo. FEBS Lett 517, 225-228. (Pubitemid 34327664)
    • (2002) FEBS Letters , vol.517 , Issue.1-3 , pp. 225-228
    • Jeong, D.-W.1    Kim, T.S.2    Chung, Y.W.3    Lee, B.J.4    Kim, I.Y.5
  • 195
    • 33748919323 scopus 로고    scopus 로고
    • Identification and characterization of selenoprotein K: An antioxidant in cardiomyocytes
    • DOI 10.1016/j.febslet.2006.08.065, PII S0014579306010283
    • Lu C, Qiu F, Zhou H, Peng Y, Hao W, Xu J, Yuan J, Wang S, Qiang B, Xu C (2006) Identification and characterization of selenoprotein K: an antioxidant incardiomyocytes. FEBS Lett 580, 5189-5197. (Pubitemid 44430096)
    • (2006) FEBS Letters , vol.580 , Issue.22 , pp. 5189-5197
    • Lu, C.1    Qiu, F.2    Zhou, H.3    Peng, Y.4    Hao, W.5    Xu, J.6    Yuan, J.7    Wang, S.8    Qiang, B.9    Xu, C.10    Peng, X.11
  • 196
    • 35748932403 scopus 로고    scopus 로고
    • Methionine sulfoxide reductases: Selenoprotein forms and roles in antioxidant protein repair in mammals
    • DOI 10.1042/BJ20070929
    • Kim HY, Gladyshev VN (2007) Methionine sulfoxide reduc-tases: selenoprotein forms and roles in antioxidant protein repair in mammals. Biochem J 407, 321-329. (Pubitemid 350058466)
    • (2007) Biochemical Journal , vol.407 , Issue.3 , pp. 321-329
    • Kim, H.-Y.1    Gladyshev, V.N.2
  • 199
    • 0037174835 scopus 로고    scopus 로고
    • Methionine 35 oxidation reduces fibril assembly of the amyloid aβ-(1-42) peptide of Alzheimer's disease
    • DOI 10.1074/jbc.C200338200
    • Hou L, Kang I, Marchant RE, Zagorski MG (2002) Methio-nine 35 oxidation reduces fibril assembly of the amyloid abeta-(1-42) peptide of Alzheimer's disease. J Biol Chem 277, 40173-40176. (Pubitemid 35215584)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.43 , pp. 40173-40176
    • Hou, L.1    Kang, I.2    Marchant, R.E.3    Zagorski, M.G.4
  • 200
    • 12844260763 scopus 로고    scopus 로고
    • Methionine oxidation by reactive oxygen species: Reaction mechanisms and relevance to Alzheimer's disease
    • DOI 10.1016/j.bbapap.2004.09.009, PII S1570963904002493, Mewthionine Oxidation and Methionine Sulfoxide Reductases
    • Schöneich C (2005) Methionine oxidation by reactive oxygen species: reaction mechanisms and relevance to Alzheimer's disease. Biochim Biophys Acta 1703, 111-119. (Pubitemid 40170434)
    • (2005) Biochimica et Biophysica Acta - Proteins and Proteomics , vol.1703 , Issue.2 , pp. 111-119
    • Schoneich, C.1
  • 201
    • 4244218956 scopus 로고    scopus 로고
    • Cyclic oxidation and reduction of protein methionine residues is an important antioxidant mechanism
    • DOI 10.1023/A:1015916831583
    • Stadtman ER, Moskovitz J, Berlett BS, Levine RL (2002) Cyclic oxidation and reduction of protein methionine residues is an important antioxidant mechanism. Mol Cell Biochem 234, 3-9. (Pubitemid 34777836)
    • (2002) Molecular and Cellular Biochemistry , vol.234-235 , pp. 3-9
    • Stadtman, E.R.1    Moskovitz, J.2    Berlett, B.S.3    Levine, R.L.4
  • 202
    • 0038611016 scopus 로고    scopus 로고
    • Selenium-deficient diet enhances protein oxidation and affects methionine sulfoxide reductase (MsrB) protein level in certain mouse tissues
    • DOI 10.1073/pnas.1332607100
    • Moskovitz J, Stadtman ER (2003) Selenium-deficient diet enhances protein oxidation and affects methionine sulfoxide reductase (MsrB) protein levelincertain mouse tissues.Proc Natl Acad Sci USA 100, 7486-7490. (Pubitemid 36759996)
    • (2003) Proceedings of the National Academy of Sciences of the United States of America , vol.100 , Issue.13 , pp. 7486-7490
    • Moskovitz, J.1    Stadtman, E.R.2
  • 204
    • 0031870668 scopus 로고    scopus 로고
    • Cellular glutathione peroxidase is the mediator of body selenium to protect against paraquat lethality in transgenic mice
    • Cheng WH, Ho YS, Valentine BA, Ross DA, Combs GF Jr, Lei XG (1998) Cellular glutathione peroxidase is the mediator of body selenium to protect against paraquat lethality in transgenic mice. J Nutr 128, 1070-1076. (Pubitemid 28317668)
    • (1998) Journal of Nutrition , vol.128 , Issue.7 , pp. 1070-1076
    • Cheng, W.-H.1    Ho, Y.-S.2    Valentine, B.A.3    Ross, D.A.4    Combs Jr., G.F.5    Lei, X.G.6
  • 205
    • 0038647490 scopus 로고    scopus 로고
    • Selenium and selenoproteins in the brain and brain diseases
    • DOI 10.1046/j.1471-4159.2003.01854.x
    • Chen J, Berry MJ (2003) Selenium and selenoproteins in the brain and brain diseases. J Neurochem 86, 1-12. (Pubitemid 36753840)
    • (2003) Journal of Neurochemistry , vol.86 , Issue.1 , pp. 1-12
    • Chen, J.1    Berry, M.J.2
  • 206
    • 75149149368 scopus 로고    scopus 로고
    • Oxidative stress status and RNA expression in hippocampus of an animal model of Alzheimer's disease after chronic exposure to aluminum
    • Garcia T, Esparza JL, Nogués MR, Romeu M, Domingo JL, Gómez M (2010) Oxidative stress status and RNA expression in hippocampus of an animal model of Alzheimer's disease after chronic exposure to aluminum. Hippocampus 20, 218-225.
    • (2010) Hippocampus , vol.20 , pp. 218-225
    • Garcia, T.1    Esparza, J.L.2    Nogués, M.R.3    Romeu, M.4    Domingo, J.L.5    Gómez, M.6
  • 208
    • 0029908623 scopus 로고    scopus 로고
    • Comparative effects of exercise training on transcription of antioxidant enzyme and the activity in old rat heart
    • Somani SM, Rybak LP (1996) Comparative effects of exercise training on transcription of antioxidant enzyme and the activity in old rat heart. Indian J Physiol Pharmacol 40, 205-212. (Pubitemid 26253745)
    • (1996) Indian Journal of Physiology and Pharmacology , vol.40 , Issue.3 , pp. 205-212
    • Somani, S.M.1    Rybak, L.P.2
  • 209
    • 0034884001 scopus 로고    scopus 로고
    • A comparative study on effect of dietary selenium and vitamin E on some antioxidant enzyme activities of liver and brain tissues
    • DOI 10.1385/BTER:81:2:141
    • Turan B, Acan NL, Ulusu NN, Tezcan EF (2001) A comparative study on effect of dietary selenium and vitamin E on some antioxidant enzyme activitiesofliver and brain tissues. Biol Trace Elem Res 81, 141-152. (Pubitemid 32777776)
    • (2001) Biological Trace Element Research , vol.81 , Issue.2 , pp. 141-152
    • Turan, B.1    Acan, N.L.2    Ulusu, N.N.3    Tezcan, E.F.4
  • 210
    • 34250898788 scopus 로고    scopus 로고
    • Effect of aldehydes derived from oxidative deamination and oxidative stress on β-amyloid aggregation; Pathological implications to Alzheimer's disease
    • DOI 10.1007/s00702-007-0697-5, Amine Oxidases from bench to bedside
    • Chen K, Kazachkov M, Yu PH (2007) Effect of aldehydes derived from oxidative deamination and oxidative stress on beta-amyloid aggregation; pathological implications to Alzheimer's disease. J Neural Transm 114, 835-839. (Pubitemid 46980494)
    • (2007) Journal of Neural Transmission , vol.114 , Issue.6 , pp. 835-839
    • Chen, K.1    Kazachkov, M.2    Yu, P.H.3
  • 211
    • 0036660272 scopus 로고    scopus 로고
    • Elevated glutathione as a therapeutic strategy in Alzheimer's disease
    • DOI 10.1002/ddr.10095
    • Butterfield DA, Pocernich CB, Drake J (2002) Elevated glu-tathione as a therapeutic strategy in Alzheimer's disease. Drug Dev Res 56, 428-437. (Pubitemid 35168319)
    • (2002) Drug Development Research , vol.56 , Issue.3 , pp. 428-437
    • Butterfield, D.A.1    Pocernich, C.B.2    Drake, J.3
  • 212
  • 214
    • 20944435890 scopus 로고    scopus 로고
    • Emerging roles of thioredoxin cycle enzymes in the central nervous system
    • DOI 10.1007/s00018-005-4541-5
    • Patenaude A, Murthy MR, Mirault ME (2005) Emerging roles of thioredoxin cycle enzymes in the central nervous system. Cell Mol Life Sci 62, 1063-1080. (Pubitemid 40868526)
    • (2005) Cellular and Molecular Life Sciences , vol.62 , Issue.10 , pp. 1063-1080
    • Patenaude, A.1    Murthy, M.R.V.2    Mirault, M.-E.3
  • 215
    • 0035112495 scopus 로고    scopus 로고
    • Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal cultures
    • DOI 10.1016/S0197-4580(00)00235-9, PII S0197458000002359
    • Lovell MA, Xie C, Markesbery WR (2001) Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal cultures. Neurobiol Aging 22, 187-194. (Pubitemid 32162967)
    • (2001) Neurobiology of Aging , vol.22 , Issue.2 , pp. 187-194
    • Lovell, M.A.1    Xie, C.2    Markesbery, W.R.3
  • 216
    • 0032968517 scopus 로고    scopus 로고
    • 4-Hydroxynonenal inhibits glutathione peroxidase: Protection by glutathione
    • DOI 10.1016/S0891-5849(98)00335-9, PII S0891584998003359
    • Bosch-Morell F, Flohé L, Maŕin N, Romero FJ (1999) 4-Hydroxynonenal inhibits glutathione peroxidase: protection by glutathione. Free Radic Biol Med 26, 1383-1387. (Pubitemid 29302270)
    • (1999) Free Radical Biology and Medicine , vol.26 , Issue.11-12 , pp. 1383-1387
    • Bosch-Morell, F.1    Flohe, L.2    Marin, N.3    Romero, F.J.4
  • 217
    • 0029764601 scopus 로고    scopus 로고
    • S-nitrosoglutathione is cleaved by the thioredoxin system with liberation of glutathione and redox regulating nitric oxide
    • DOI 10.1074/jbc.271.32.19180
    • Nikitovic D, Holmgren A (1996) S-nitrosoglutathione is cleaved by the thioredoxin system with liberation of glu-tathione and redox regulating nitric oxide. J Biol Chem 271, 19180-19185. (Pubitemid 26271582)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.32 , pp. 19180-19185
    • Nikitovic, D.1    Holmgren, A.2
  • 219
    • 51849150799 scopus 로고    scopus 로고
    • Lipid peroxidation up-regulates BACE1 expression in vivo: A possible early event of amyloidogenesis in Alzheimer's disease
    • Chen L, Na R, Gu M, Richardson A, Ran Q (2008) Lipid peroxidation up-regulates BACE1 expression in vivo: a possible early event of amyloidogenesis in Alzheimer's disease. J Neurochem 107, 197-207.
    • (2008) J Neurochem , vol.107 , pp. 197-207
    • Chen, L.1    Na, R.2    Gu, M.3    Richardson, A.4    Ran, Q.5
  • 220
    • 77954517681 scopus 로고    scopus 로고
    • Reduced reelin expression accelerates Amyloid-beta plaque formation and tau pathology in transgenic Alzheimer's disease mice
    • Kocherhans S, Madhusudan A, Doehner J, Breu KS, Nitsch RM, Fritschy JM, Knuesel I (2010) Reduced reelin expression accelerates Amyloid-beta plaque formation and tau pathology in transgenic Alzheimer's disease mice. J Neu-rosci 30, 9228-9240.
    • (2010) J Neu-rosci , vol.30 , pp. 9228-9240
    • Kocherhans, S.1    Madhusudan, A.2    Doehner, J.3    Breu, K.S.4    Nitsch, R.M.5    Fritschy, J.M.6    Knuesel, I.7
  • 222
    • 70349638299 scopus 로고    scopus 로고
    • Advances in tau-focused drug discovery for Alzheimer's disease and related tauopathies
    • Brunden KR, Trojanowski JQ, Virginia VM (2009) Advances in tau-focused drug discovery for Alzheimer's disease and related tauopathies. Nat Rev Drug Discov 8, 783-793.
    • (2009) Nat Rev Drug Discov , vol.8 , pp. 783-793
    • Brunden, K.R.1    Trojanowski, J.Q.2    Virginia, V.M.3
  • 226
    • 0035075793 scopus 로고    scopus 로고
    • PP2A mRNA expression is quantitatively decreased in Alzheimer's disease hippocampus
    • DOI 10.1006/exnr.2001.7630
    • Vogelsberg-Ragaglia V, Schuck T, Trojanowski JQ, Lee VM (2001) PP2A mRNA expression is quantitatively decreased in Alzheimer's disease hippocampus. Exp Neurol 168, 402-412. (Pubitemid 32289776)
    • (2001) Experimental Neurology , vol.168 , Issue.2 , pp. 402-412
    • Vogelsberg-Ragaglia, V.1    Schuck, T.2    Trojanowski, J.Q.3    Lee, V.M.-Y.4
  • 229
    • 67649392464 scopus 로고    scopus 로고
    • Alzheimer's disease, metal ions and metal homeostatic therapy
    • Zatta P, Drago D, Bolognin S, Sensi SL (2009) Alzheimer's disease, metal ions and metal homeostatic therapy. Trends Pharmacol Sci 30, 346-355.
    • (2009) Trends Pharmacol Sci , vol.30 , pp. 346-355
    • Zatta, P.1    Drago, D.2    Bolognin, S.3    Sensi, S.L.4
  • 232
    • 0026583944 scopus 로고
    • Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity
    • Xanthoudakis S, Curran T (1992) Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity. EMBO J 11, 653-665.
    • (1992) EMBO J , vol.11 , pp. 653-665
    • Xanthoudakis, S.1    Curran, T.2
  • 234
    • 0031172065 scopus 로고    scopus 로고
    • NF-κB: A crucial transcription factor for glial and neuronal cell function
    • DOI 10.1016/S0166-2236(96)01035-1
    • O'neill LA, Kaltschmidt C (1997) NF-kB: a crucial transcription factor for glial and neuronal cell function. Trends Neurosci 20, 252-258. (Pubitemid 27261456)
    • (1997) Trends in Neurosciences , vol.20 , Issue.6 , pp. 252-258
    • O'Neill, L.A.J.1    Kaltschmidt, C.2
  • 235
    • 0030222080 scopus 로고    scopus 로고
    • Induction of neuroprotective κB-dependent transcription by secreted forms of the Alzheimer's β-amyloid precursor
    • DOI 10.1016/0169-328X(96)00036-8
    • Barger SW, Mattson MP (1996) Induction of neuroprotec-tive kappa B-dependent transcription by secreted forms of the Alzheimer's beta-amyloid precursor. Mol Brain Res 40, 116-126. (Pubitemid 26241792)
    • (1996) Molecular Brain Research , vol.40 , Issue.1 , pp. 116-126
    • Barger, S.W.1    Mattson, M.P.2
  • 236
    • 0034727901 scopus 로고    scopus 로고
    • The lipid peroxidation product 4-hydroxy-2,3-nonenal inhibits constitutive and inducible activity of nuclear factor κB in neurons
    • DOI 10.1016/S0169-328X(00)00234-5, PII S0169328X00002345
    • Camandola S, Poli G, Mattson MP (2000) The lipid peroxi-dation product 4-hydroxy-2, 3-nonenal inhibits constitutive and inducible activity of nuclear factor kappa B in neurons. Mol Brain Res 85, 53-60. (Pubitemid 32056236)
    • (2000) Molecular Brain Research , vol.85 , Issue.1-2 , pp. 53-60
    • Camandola, S.1    Poli, G.2    Mattson, M.P.3
  • 237
    • 0028106342 scopus 로고
    • A direct role for protein kinase C and the transcription factor jun/AP-1 in the regulation of the Alzheimer's β-amyloid precursor protein gene
    • Trejo J, Massamiri T, Deng T, Dewji NN, Bayney RM, Brown JH (1994) A direct role for protein kinase C and the transcription factor Jun/AP-1 in the regulation of the Alzheimer's beta-amyloid precursor protein gene. J Biol Chem 269, 21682-21690. (Pubitemid 24274808)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.34 , pp. 21682-21690
    • Trejo, J.1    Massamiri, T.2    Deng, T.3    Dewji, N.N.4    Bayney, R.M.5    Brown, J.H.6
  • 241
    • 33847112418 scopus 로고    scopus 로고
    • The NF-kB regulatory network
    • Brasier A (2006) The NF-kB regulatory network. Cardio-vasc Toxicol 6, 111-130.
    • (2006) Cardio-vasc Toxicol , vol.6 , pp. 111-130
    • Brasier, A.1
  • 242
    • 0026970404 scopus 로고
    • Nuclear factor κβ: An oxidative stress-responsive transcription factor of eukaryotic cells (A review)
    • Schreck R, Albermann K, Baeuerle PA (1992) Nuclear factor kappa B: an oxidative stress-responsive transcription factor of eukaryotic cells (a review). Free Radic Res 17, 221-237. (Pubitemid 23207431)
    • (1992) Free Radical Research Communications , vol.17 , Issue.4 , pp. 221-237
    • Schreck, R.1    Albermann, K.2    Baeuerle, P.A.3
  • 244
    • 0030055822 scopus 로고    scopus 로고
    • Selenium-mediated inhibition of transcription factor NF-kappa B and HIV-1 LTR promoter activity
    • Makropoulos V, Brüning T, Schulze-Osthoff K (1996) Selenium-mediated inhibition of transcription factor NF-kappa B and HIV-1 LTR promoter activity. Arch Toxicol 70, 277-283.
    • (1996) Arch Toxicol , vol.70 , pp. 277-283
    • Makropoulos, V.1    Brüning, T.2    Schulze-Osthoff, K.3
  • 245
    • 0030702951 scopus 로고    scopus 로고
    • Interleukin-1-induced nuclear factor κB activation is inhibited by overexpression of phospholipid hydroperoxide glutathione peroxidase in a human endothelial cell line
    • Brigelius-Flohe R, Friedrichs B, Maurer S, Schultz M, Streicher R (1997) Interleukin-1-induced nuclear factor kappa B activation is inhibited by overexpression of phos-pholipid hydroperoxide glutathione peroxidase in a human endothelial cell line. Biochem J 328, 199-203. (Pubitemid 27499459)
    • (1997) Biochemical Journal , vol.328 , Issue.1 , pp. 199-203
    • Brigelius-Flohe, R.1    Friedrichs, B.2    Maurer, S.3    Schultz, M.4    Streicher, R.5
  • 246
    • 0035476441 scopus 로고    scopus 로고
    • Modulation of the Ras/MAPK signalling pathway by the redox function of selenoproteins in Drosophila melanogaster
    • DOI 10.1006/dbio.2001.0389
    • Morey M, Serras F, Baguñá J, Hafen E, Corominas M (2001) Modulation of the Ras/MAPK signalling pathway by the redox function of selenoproteins in Drosophila melanogaster. Dev Biol 238, 145-156. (Pubitemid 32939292)
    • (2001) Developmental Biology , vol.238 , Issue.1 , pp. 145-156
    • Morey, M.1    Serras, F.2    Bagua, J.3    Hafen, E.4    Corominas, M.5
  • 247
    • 68749107989 scopus 로고    scopus 로고
    • Attenuated expression of SECIS binding protein 2 causes loss of telom-eric reserve without affecting telomerase
    • Squires JE, Davy P, Berry MJ, Allsopp R (2009) Attenuated expression of SECIS binding protein 2 causes loss of telom-eric reserve without affecting telomerase. Exp Gerontol 44, 619-623.
    • (2009) Exp Gerontol , vol.44 , pp. 619-623
    • Squires, J.E.1    Davy, P.2    Berry, M.J.3    Allsopp, R.4
  • 248
    • 6344234789 scopus 로고    scopus 로고
    • Effects of trace elements on the telomere lengths of hepatocytes L-02 and hepatoma cells SMMC-7721
    • DOI 10.1385/BTER:100:3:215
    • Liu Q, Wang H, Hu D, Ding C, Xu H, Tao D (2004) Effects of trace elements on the telomere lengths of hepatocytes L-02 and hepatoma cells SMMC-7721. Biol Trace Elem Res 100, 215-227. (Pubitemid 39390050)
    • (2004) Biological Trace Element Research , vol.100 , Issue.3 , pp. 215-227
    • Liu, Q.1    Wang, H.2    Hu, D.3    Ding, C.4    Xu, H.5    Tao, D.6
  • 249
    • 0036032355 scopus 로고    scopus 로고
    • Effects of lead and selenium on telomere binding protein Rap1 p, telomerase and telomeric DNA in Saccharomyces cerevisiae
    • Cui QH, Tang CC, Huang YG (2002) Effects of lead and selenium on telomere binding protein Rap1 p, telomerase and telomeric DNA in Saccharomyces cerevisiae. Acta Biochim Biophys Sin 34, 240-244.
    • (2002) Acta Biochim Biophys Sin , vol.34 , pp. 240-244
    • Cui, Q.H.1    Tang, C.C.2    Huang, Y.G.3
  • 250
    • 33746812586 scopus 로고    scopus 로고
    • Shorter telomeres are associated with mortality in those with APOE ε4 and dementia
    • DOI 10.1002/ana.20894
    • Honig LS, Schupf N, Lee JH, Tang MX, Mayeux R (2006) Shorter telomeres are associated with mortality in those with APOE epsilon4 and dementia. Ann Neurol 60, 181-187. (Pubitemid 44182393)
    • (2006) Annals of Neurology , vol.60 , Issue.2 , pp. 181-187
    • Honig, L.S.1    Schupf, N.2    Lee, J.H.3    Tang, M.X.4    Mayeux, R.5
  • 251
    • 39749173730 scopus 로고    scopus 로고
    • Telomere length in white blood cells, buccal cells and brain tissue and its variation with ageing and Alzheimer's disease
    • Thomas P, O'Callaghan NJ, Fenech M (2008) Telomere length in white blood cells, buccal cells and brain tissue and its variation with ageing and Alzheimer's disease. Mech Ageing Dev 129, 183-190.
    • (2008) Mech Ageing Dev , vol.129 , pp. 183-190
    • Thomas, P.1    O'Callaghan, N.J.2    Fenech, M.3
  • 254
    • 0036523032 scopus 로고    scopus 로고
    • Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease
    • Kruman II, Kumaravel TS, Lohani A, Pedersen WA, Cutler RG, Kruman Y, Haughey N, Lee J, Evans M, Mattson MP (2002) Folic acid deficiency and homocysteine impair DNArepair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models ofAlzheimer's disease. J Neurosci 22, 1752-1762. (Pubitemid 35386293)
    • (2002) Journal of Neuroscience , vol.22 , Issue.5 , pp. 1752-1762
    • Kruman, I.I.1    Kumaravel, T.S.2    Lohani, A.3    Pedersen, W.A.4    Cutler, R.G.5    Kruman, Y.6    Haughey, N.7    Lee, J.8    Evans, M.9    Mattson, M.P.10
  • 255
    • 33747391975 scopus 로고    scopus 로고
    • Elevated plasma homocysteine levels: Risk factor or risk marker for the development of dementia and Alzheimer's disease?
    • Seshadri S (2006) Elevated plasma homocysteine levels: risk factor or risk marker for the development of dementia and Alzheimer's disease? J Alzheimers Dis 9, 393-398.
    • (2006) J Alzheimers Dis , vol.9 , pp. 393-398
    • Seshadri, S.1
  • 256
    • 0032771346 scopus 로고    scopus 로고
    • Homocysteine metabolism
    • DOI 10.1146/annurev.nutr.19.1.217
    • Selhub J (1999) Homocysteine metabolism. Annu Rev Nutr 19, 217-246. (Pubitemid 29380603)
    • (1999) Annual Review of Nutrition , vol.19 , pp. 217-246
    • Selhub, J.1
  • 257
    • 0036892748 scopus 로고    scopus 로고
    • Multiple aspects of homocysteine neurotoxicity: Glutamate excitotoxicity, kinase hyperactivation and DNA damage
    • DOI 10.1002/jnr.10416
    • Ho PI, Ortiz D, Rogers E, Shea TB (2002) Multiple aspects of homocysteine neurotoxicity: glutamate excitotoxicity, kinase hyperactivation and DNA damage. J Neurosci Res 70, 694-702. (Pubitemid 35397143)
    • (2002) Journal of Neuroscience Research , vol.70 , Issue.5 , pp. 694-702
    • Ho, P.I.1    Ortiz, D.2    Rogers, E.3    Shea, T.B.4
  • 258
    • 0034678050 scopus 로고    scopus 로고
    • Homocysteine accelerates endothelial cell senescence
    • DOI 10.1016/S0014-5793(00)01278-3, PII S0014579300012783
    • Xu D, Neville R, Finkel T (2000) Homocysteine accelerates endothelial cell senescence. FEBS Lett 470, 20-24. (Pubitemid 30155616)
    • (2000) FEBS Letters , vol.470 , Issue.1 , pp. 20-24
    • Xu, D.1    Neville, R.2    Finkel, T.3
  • 259
    • 0037042211 scopus 로고    scopus 로고
    • Protein phosphatase 2A methylation: A link between elevated plasma homocysteine and Alzheimer's Disease
    • DOI 10.1016/S0014-5793(02)02702-3, PII S0014579302027023
    • Vafai SB, Stock JB (2002) Protein phosphatase 2A methy-lation: a link between elevated plasma homocysteine and Alzheimer's disease. FEBS Lett 518, 1-4. (Pubitemid 34454953)
    • (2002) FEBS Letters , vol.518 , Issue.1-3 , pp. 1-4
    • Vafai, S.B.1    Stock, J.B.2
  • 263
    • 67349239451 scopus 로고    scopus 로고
    • Alzheimer's Disease as a neurotransmitter disease
    • Dawbarn D, Shelley A, eds. Oxford. University Press, New York
    • Lai MK, Ramirez MJ, Tsang SW, Francis PT (2007) Alzheimer's Disease as a neurotransmitter disease. In Neu-robiology of Alzheimer's Disease, Dawbarn D, Shelley A, eds. Oxford University Press, New York, pp. 245-283.
    • (2007) Neu-robiology of Alzheimer's Disease , pp. 245-283
    • Lai, M.K.1    Ramirez, M.J.2    Tsang, S.W.3    Francis, P.T.4
  • 264
    • 0042433479 scopus 로고    scopus 로고
    • The cholinergic hypothesis of age and Alzheimer's disease-related cognitive deficits: Recent challenges and their implications for novel drug development
    • DOI 10.1124/jpet.102.041616
    • Terry AV Jr, Buccafusco JJ (2003) The cholinergic hypothesis ofage and Alzheimer's disease-related cognitive deficits: recent challenges and their implications for novel drug development. J Pharmacol Exp Ther 306, 821-827. (Pubitemid 37025286)
    • (2003) Journal of Pharmacology and Experimental Therapeutics , vol.306 , Issue.3 , pp. 821-827
    • Terry Jr., A.V.1    Buccafusco, J.J.2
  • 266
    • 70449623632 scopus 로고    scopus 로고
    • Amyloi-dosis and neurodegenerative diseases: Current treatments and new pharmacological options
    • Tillement JP, Lecanu L, Papadopoulos V (2009) Amyloi-dosis and neurodegenerative diseases: current treatments and new pharmacological options. Pharmacology 85, 1-17.
    • (2009) Pharmacology , vol.85 , pp. 1-17
    • Tillement, J.P.1    Lecanu, L.2    Papadopoulos, V.3
  • 267
    • 0036830947 scopus 로고    scopus 로고
    • Calcium dyshomeostasis and intracel-lular signalling in Alzheimer's disease
    • LaFerla FM (2002) Calcium dyshomeostasis and intracel-lular signalling in Alzheimer's disease. Nat Rev Neurosci 3, 862-872.
    • (2002) Nat Rev Neurosci , vol.3 , pp. 862-872
    • Laferla, F.M.1
  • 268
    • 33947114148 scopus 로고    scopus 로고
    • Altered hippocampus synaptic function in selenoprotein P deficient mice
    • Peters MM, Hill KE, Burk RF, Weeber EJ (2006) Altered hippocampus synaptic function in selenoprotein P deficient mice. Mol Neurodegener 1, 12.
    • (2006) Mol Neurodegener , vol.1 , pp. 12
    • Peters, M.M.1    Hill, K.E.2    Burk, R.F.3    Weeber, E.J.4
  • 269
    • 84984585825 scopus 로고    scopus 로고
    • Diphenyl diselenide and diphenyl ditelluride affect the rat glutamatergic system in vitro and in vivo
    • DOI 10.1016/S0006-8993(01)02165-5, PII S0006899301021655
    • Nogueira CW, Rotta LN, Perry ML, Souza DO, da Rocha JB (2001) Diphenyl diselenide and diphenyl ditelluride affect the rat glutamatergic system in vitro and in vivo. Brain Res 906, 157-163. (Pubitemid 32595550)
    • (2001) Brain Research , vol.906 , Issue.1-2 , pp. 157-163
    • Nogueira, C.W.1    Rotta, L.N.2    Perry, M.L.3    Souza, D.O.4    Teixeira Da Rocha, J.B.5
  • 270
    • 78650844719 scopus 로고    scopus 로고
    • Does inorganic mercury play a role in Alzheimer's disease? A systematic review and an integrated molecular mechanism
    • Mutter J, Curth A, Naumann R, Deth R, Walach H (2010) Does inorganic mercury play a role in Alzheimer's disease? A systematic review and an integrated molecular mechanism. J Alzheimers Dis 22, 357-374.
    • (2010) J Alzheimers Dis , vol.22 , pp. 357-374
    • Mutter, J.1    Curth, A.2    Naumann, R.3    Deth, R.4    Walach, H.5
  • 271
    • 67349190556 scopus 로고    scopus 로고
    • Mercury toxicity and the mitigating role of selenium
    • Berry MJ, Ralston NV (2008) Mercury toxicity and the mitigating role of selenium. Eco Health 5, 456-459.
    • (2008) Eco Health , vol.5 , pp. 456-459
    • Berry, M.J.1    Ralston, N.V.2
  • 272
    • 52149091237 scopus 로고    scopus 로고
    • Selenium and mercury in organisms: Interactions and mechanisms
    • Yang DY, Chen YW, Gunn JM, Belzile N (2008) Selenium and mercury in organisms: interactions and mechanisms. Environ Rev 16, 71-92.
    • (2008) Environ Rev , vol.16 , pp. 71-92
    • Yang, D.Y.1    Chen, Y.W.2    Gunn, J.M.3    Belzile, N.4
  • 273
    • 33747195078 scopus 로고    scopus 로고
    • Mercury: Selenium interactions and health implications
    • Raymond LJ, Ralston NV (2004) Mercury: selenium interactions and health implications. Seychelles Med Dent J 7, 72-77.
    • (2004) Seychelles Med Dent J , vol.7 , pp. 72-77
    • Raymond, L.J.1    Ralston, N.V.2
  • 274
    • 0026149323 scopus 로고
    • The sulphur-mercury (II) system in natural waters
    • Dyrssen D, Wedborg M (1991) The sulphur-mercury (II) system in natural waters. Water Air Soil Pollut 56, 507-519.
    • (1991) Water Air Soil Pollut , vol.56 , pp. 507-519
    • Dyrssen, D.1    Wedborg, M.2
  • 276
    • 0030823798 scopus 로고    scopus 로고
    • Mercury vapor inhalation inhibits binding of GTP to tubulin in rat brain: Similarity to a molecular lesion in Alzheimer Diseased Brain
    • Pendergrass JC, Haley BE, Vimy MJ, Winfield SA, Lorscheider FL (1997) Mercury vapor inhalation inhibits binding of GTP to tubulin rat brain: similarity to a molecular lesion in Alzheimer diseases brain. Neurotoxicology 18, 315-324. (Pubitemid 27392641)
    • (1997) NeuroToxicology , vol.18 , Issue.2 , pp. 315-324
    • Pendergrass, J.C.1    Haley, B.E.2    Vimy, M.J.3    Winfield, S.A.4    Lorscheider, F.L.5
  • 277
    • 0033957486 scopus 로고    scopus 로고
    • Mercury induces cell cytotoxicity and oxidative stress and increases β- amyloid secretion and tau phosphorylation in SHSY5Y neuroblastoma cells
    • DOI 10.1046/j.1471-4159.2000.0740231.x
    • Olivieri G, Brack C, Müller-Spahn F, Stähelin HB, Herrmann M, Renard P, Brockhaus M, Hock C (2000) Mercury induces cell cytotoxicity and oxidative stress and increases-amyloid secretion and tau phosphorylation in SHSY5Y neuroblastoma cells. J Neurochem 74, 231-236. (Pubitemid 30012773)
    • (2000) Journal of Neurochemistry , vol.74 , Issue.1 , pp. 231-236
    • Olivieri, G.1    Brack, Ch.2    Muller-Spahn, F.3    Stahelin, H.B.4    Herrmann, M.5    Renard, P.6    Brockhaus, M.7    Hock, C.8
  • 278
    • 0037055996 scopus 로고    scopus 로고
    • The effects of β-estradiol on SHSY5Y neuroblastoma cells during heavy metal induced oxidative stress, neurotoxicity and β-amyloid secretion
    • DOI 10.1016/S0306-4522(02)00211-7, PII S0306452202002117
    • Olivieri G, Novakovic M, Savaskan E, Meier F, Baysang G, Brockhaus M, Müller-Spahn F (2002) The effects of beta-estradiol on SHSY5Y neuroblastoma cells during heavy metal induced oxidative stress, neurotoxicity and beta-amyloid secretion. Neuroscience 113, 849-855. (Pubitemid 35245254)
    • (2002) Neuroscience , vol.113 , Issue.4 , pp. 849-855
    • Olivieri, G.1    Novakovic, M.2    Savaskan, E.3    Meier, F.4    Baysang, G.5    Brockhaus, M.6    Muller-Spahn, F.7
  • 282
    • 0027979195 scopus 로고
    • Recovery from amyotrophic lateral scoliosis and from allergy after removal of dental amalgam fillings
    • Redhe O, Pleva J (1993) Recovery from amyotrophic lateral sclerosis and from allergy after removal of dental amalgam fillings. Int J Risk Saf Med 4, 229-236. (Pubitemid 24026227)
    • (1994) International Journal of Risk and Safety in Medicine , vol.4 , Issue.3 , pp. 229-236
    • Rehee, O.1    Pleva, J.2
  • 285
    • 23844441923 scopus 로고    scopus 로고
    • More roles for selenoprotein P: Local selenium storage and recycling protein inthe brain
    • Richardson DR (2005) More roles for selenoprotein P: local selenium storage and recycling protein inthe brain.Biochem J 386, e5-e7.
    • (2005) Biochem J , vol.386
    • Richardson, D.R.1
  • 286
    • 73049095378 scopus 로고    scopus 로고
    • Hierarchical regulation of selenoprotein expression and sex-specific effects of selenium
    • Schomburg L, Schweizer U (2009) Hierarchical regulation of selenoprotein expression and sex-specific effects of selenium. Biochim Biophys Acta 1790, 1453-1462.
    • (2009) Biochim Biophys Acta , vol.1790 , pp. 1453-1462
    • Schomburg, L.1    Schweizer, U.2
  • 287
    • 3042693925 scopus 로고    scopus 로고
    • Selenium and brain function: A poorly recognized liaison
    • DOI 10.1016/j.brainresrev.2004.03.004, PII S0165017304000347
    • Schweizer U, Bräuer AU, Köhrle J, Nitsch R, Savaskan NE (2004) Selenium and brain function: a poorly recognized liaison. Brain Res Rev 45, 164-178. (Pubitemid 38802869)
    • (2004) Brain Research Reviews , vol.45 , Issue.3 , pp. 164-178
    • Schweizer, U.1    Brauer, A.U.2    Kohrle, J.3    Nitsch, R.4    Savaskan, N.E.5
  • 288
  • 289
    • 74949117713 scopus 로고    scopus 로고
    • Zinc deficiency reduces neurogenesis accompanied by neuronal apoptosis through caspase-dependent and-independent signaling pathways
    • Gao HL, Zheng W, Xin N, Chi ZH, Wang ZY, Chen J, Wang ZY (2009) Zinc deficiency reduces neurogenesis accompanied by neuronal apoptosis through caspase-dependent and-independent signaling pathways.Neurotox Res 16, 416-425.
    • (2009) Neurotox Res , vol.16 , pp. 416-425
    • Gao, H.L.1    Zheng, W.2    Xin, N.3    Zh, C.4    Wang, Z.Y.5    Chen, J.6    Wang, Z.Y.7
  • 290
    • 0034952716 scopus 로고    scopus 로고
    • The importance of zinc in human nutrition and estimation of the global prevalence of zinc deficiency
    • Recent intervention trials with zinc
    • Brown KH, Wuehler SE, Peerson JM (2001) The importance of zinc in human nutrition and estimation of the global prevalence of zinc deficiency. Food Nutr Bull 22, 113-125. (Pubitemid 32653119)
    • (2001) Food and Nutrition Bulletin , vol.22 , Issue.2 , pp. 113-125
    • Brown, K.H.1    Wuehler, S.E.2    Peerson, J.M.3
  • 292
    • 0016839980 scopus 로고
    • Biochemical function of selenium and its relation to vitamin e
    • Hoekstra W (1975) Biochemical function of selenium and its relation to vitamin E. Fed Broc 11, 2083-2089.
    • (1975) Fed Broc , vol.11 , pp. 2083-2089
    • Hoekstra, W.1
  • 293
    • 0642311543 scopus 로고    scopus 로고
    • The nutritional significance, metabolism and toxicology of selenomethionine
    • DOI 10.1016/S1043-4526(03)47002-2, PII S1043452603470022
    • Schrauzer GN (2003) The nutritional significance, metabolism and toxicology of selenomethionine. Adv Food Nutr Res 47, 73-112. (Pubitemid 137640845)
    • (2003) Advances in Food and Nutrition Research , vol.47 , pp. 73-112
    • Schrauzer, G.N.1
  • 296
    • 0023087564 scopus 로고
    • A global view of human selenium nutrition
    • Levander OA (1987) A global view of human selenium nutrition. Annu Rev Nutr 7, 227-250.
    • (1987) Annu Rev Nutr , vol.7 , pp. 227-250
    • Levander, O.A.1
  • 297
    • 0342467931 scopus 로고    scopus 로고
    • Selenium in global food systems
    • Combs GF Jr (2001) Selenium in global food systems. Br J Nutr 85, 517-547. (Pubitemid 32479141)
    • (2001) British Journal of Nutrition , vol.85 , Issue.5 , pp. 517-547
    • Combs Jr., G.F.1
  • 298
    • 0033924449 scopus 로고    scopus 로고
    • Selenomethionine: A review of its nutritional significance, metabolism and toxicity
    • Schrauzer GN (2000) Selenomethionine: a review of its nutritional significance, metabolismand toxicity.J Nutr130, 1653-1656. (Pubitemid 30451048)
    • (2000) Journal of Nutrition , vol.130 , Issue.7 , pp. 1653-1656
    • Schrauzer, G.N.1
  • 299
    • 0033793205 scopus 로고    scopus 로고
    • Redox modulation of the NMDA receptor
    • Choi YB, Lipton SA (2000) Redox modulation of the NMDA receptor. Cell Mol Life Sci 57, 1535-1541.
    • (2000) Cell Mol Life Sci , vol.57 , pp. 1535-1541
    • Choi, Y.B.1    Lipton, S.A.2


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