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Volumn 13, Issue 10, 2012, Pages 13621-13666

Tanshinones: Sources, pharmacokinetics and anti-cancer activities

Author keywords

Anti cancer; Pharmacokinetic; Sources; Tanshinones

Indexed keywords

ANDROGEN RECEPTOR; ANTINEOPLASTIC AGENT; CRYPTOTANSHINONE; CYCLOPHOSPHAMIDE; DIHYDROTANSHINONE 1; DOXORUBICIN; HERBACEOUS AGENT; MITOMYCIN; PROTEIN P53; SALVIANOLIC ACID B; SOLID LIPID NANOPARTICLE; TANSHINONE; TANSHINONE DERIVATIVE; TANSHINONE I; TANSHINONE IIA; TANSHINONE IIA SULFONATE; TELOMERASE; TERPENOID; UNCLASSIFIED DRUG; ABIETANE DERIVATIVE; ANGIOGENESIS INHIBITOR;

EID: 84870653900     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms131013621     Document Type: Review
Times cited : (213)

References (302)
  • 1
    • 27844511101 scopus 로고    scopus 로고
    • Danshen: An overview of its chemistry, pharmacology, pharmacokinetics, and clinical use
    • Zhou, L.; Zuo, Z.; Chow, M.S. Danshen: An overview of its chemistry, pharmacology, pharmacokinetics, and clinical use. J. Clin. Pharmacol. 2005, 45, 1345-1359.
    • (2005) J. Clin. Pharmacol , vol.45 , pp. 1345-1359
    • Zhou, L.1    Zuo, Z.2    Chow, M.S.3
  • 2
    • 79952035257 scopus 로고    scopus 로고
    • Biosynthesis, total syntheses, and antitumor activity of tanshinones and their analogs as potential therapeutic agents
    • Dong, Y.; Morris-Natschke, S.L.; Lee, K.H. Biosynthesis, total syntheses, and antitumor activity of tanshinones and their analogs as potential therapeutic agents. Nat. Prod. Rep. 2011, 28, 529-542.
    • (2011) Nat. Prod. Rep , vol.28 , pp. 529-542
    • Dong, Y.1    Morris-Natschke, S.L.2    Lee, K.H.3
  • 3
    • 0013189859 scopus 로고
    • On the the chemical composition of Salvia miltiorrhiza (Chinese drug Tan-shen)
    • Nakao, M.; Fukushima, T. On the the chemical composition of Salvia miltiorrhiza (Chinese drug Tan-shen). Yakugaku Zasshi 1934, 54, 844-858.
    • (1934) Yakugaku Zasshi , vol.54 , pp. 844-858
    • Nakao, M.1    Fukushima, T.2
  • 4
    • 33845768814 scopus 로고    scopus 로고
    • New developments in the chemistry and biology of the bioactive constituents of Tanshen
    • Wang, X.; Morris-Natschke, S.L.; Lee, K.H. New developments in the chemistry and biology of the bioactive constituents of Tanshen. Med. Res. Rev. 2007, 27, 133-148.
    • (2007) Med. Res. Rev , vol.27 , pp. 133-148
    • Wang, X.1    Morris-Natschke, S.L.2    Lee, K.H.3
  • 5
    • 38149068306 scopus 로고    scopus 로고
    • Preclinical factors affecting the pharmacokinetic behaviour of tanshinone IIA, an investigational new drug isolated from Salvia miltiorrhiza for the treatment of ischaemic heart diseases
    • Bi, H.C.; Zuo, Z.; Chen, X.; Xu, C.S.; Wen, Y.Y.; Sun, H.Y.; Zhao, L.Z.; Pan, Y.; Deng, Y.; Liu, P.Q.; et al. Preclinical factors affecting the pharmacokinetic behaviour of tanshinone IIA, an investigational new drug isolated from Salvia miltiorrhiza for the treatment of ischaemic heart diseases. Xenobiotica 2008, 38, 185-222.
    • (2008) Xenobiotica , vol.38 , pp. 185-222
    • Bi, H.C.1    Zuo, Z.2    Chen, X.3    Xu, C.S.4    Wen, Y.Y.5    Sun, H.Y.6    Zhao, L.Z.7    Pan, Y.8    Deng, Y.9    Liu, P.Q.10
  • 6
    • 32244445209 scopus 로고    scopus 로고
    • Cytotoxic and aromatic constituents from Salvia miltiorrhiza
    • Don, M.J.; Shen, C.C.; Syu, W.J.; Ding, Y.H.; Sun, C.M. Cytotoxic and aromatic constituents from Salvia miltiorrhiza. Phytochemistry 2006, 67, 497-503.
    • (2006) Phytochemistry , vol.67 , pp. 497-503
    • Don, M.J.1    Shen, C.C.2    Syu, W.J.3    Ding, Y.H.4    Sun, C.M.5
  • 7
    • 2942567865 scopus 로고    scopus 로고
    • Identification of major active constituents in the fingerprint of Salvia miltiorrhiza Bunge developed by high-speed counter-current chromatography
    • Gu, M.; Zhang, G.; Su, Z.; Ouyang, F. Identification of major active constituents in the fingerprint of Salvia miltiorrhiza Bunge developed by high-speed counter-current chromatography. J. Chromatogr. A 2004, 1041, 239-243.
    • (2004) J. Chromatogr. A , vol.1041 , pp. 239-243
    • Gu, M.1    Zhang, G.2    Su, Z.3    Ouyang, F.4
  • 8
    • 33846538002 scopus 로고    scopus 로고
    • Simultaneous determination of seven active components of Fufang Danshen tablet by high performance liquid chromatography
    • Wei, Y.J.; Li, S.L.; Li, P. Simultaneous determination of seven active components of Fufang Danshen tablet by high performance liquid chromatography. Biomed. Chromatogr. 2007, 21, 1-9.
    • (2007) Biomed. Chromatogr , vol.21 , pp. 1-9
    • Wei, Y.J.1    Li, S.L.2    Li, P.3
  • 9
    • 33645840150 scopus 로고    scopus 로고
    • Characterization of tanshinones in the roots of Salvia miltiorrhiza (Dan-shen) by high-performance liquid chromatography with electrospray ionization tandem mass spectrometry
    • Yang, M.; Liu, A.; Guan, S.; Sun, J.; Xu, M.; Guo, D. Characterization of tanshinones in the roots of Salvia miltiorrhiza (Dan-shen) by high-performance liquid chromatography with electrospray ionization tandem mass spectrometry. Rapid Commun. Mass Spectrom. 2006, 20, 1266-1280.
    • (2006) Rapid Commun. Mass Spectrom , vol.20 , pp. 1266-1280
    • Yang, M.1    Liu, A.2    Guan, S.3    Sun, J.4    Xu, M.5    Guo, D.6
  • 10
    • 33645080664 scopus 로고    scopus 로고
    • Simultaneous quantification of six major phenolic acids in the roots of Salvia miltiorrhiza and four related traditional Chinese medicinal preparations by HPLC-DAD method
    • Liu, A.H.; Li, L.; Xu, M.; Lin, Y.H.; Guo, H.Z.; Guo, D.A. Simultaneous quantification of six major phenolic acids in the roots of Salvia miltiorrhiza and four related traditional Chinese medicinal preparations by HPLC-DAD method. J. Pharm. Biomed. Anal. 2006, 41, 48-56.
    • (2006) J. Pharm. Biomed. Anal , vol.41 , pp. 48-56
    • Liu, A.H.1    Li, L.2    Xu, M.3    Lin, Y.H.4    Guo, H.Z.5    Guo, D.A.6
  • 11
    • 33645222408 scopus 로고    scopus 로고
    • Determination of four water-soluble compounds in Salvia miltiorrhiza Bunge by high-performance liquid chromatography with a coulometric electrode array system
    • Ma, L.; Zhang, X.; Guo, H.; Gan, Y. Determination of four water-soluble compounds in Salvia miltiorrhiza Bunge by high-performance liquid chromatography with a coulometric electrode array system. J. Chromatogr. B Anal. Technol. Biomed. Life Sci. 2006, 833, 260-263.
    • (2006) J. Chromatogr. B Anal. Technol. Biomed. Life Sci , vol.833 , pp. 260-263
    • Ma, L.1    Zhang, X.2    Guo, H.3    Gan, Y.4
  • 12
    • 0008205369 scopus 로고
    • Chemical constituents of Salvia miltiorrhiza (Danshen)
    • Kong, D.Y. Chemical constituents of Salvia miltiorrhiza (Danshen). Zhongguo Yiyao Gongye Zazhi 1989, 20, 279-285.
    • (1989) Zhongguo Yiyao Gongye Zazhi , vol.20 , pp. 279-285
    • Kong, D.Y.1
  • 13
    • 84856274682 scopus 로고    scopus 로고
    • Herbal remedies supply a novel prospect for the treatment of atherosclerosis: A review of current mechanism studies
    • Zeng, Y.; Song, J.X.; Shen, X.C. Herbal remedies supply a novel prospect for the treatment of atherosclerosis: A review of current mechanism studies. Phytother. Res. 2012, 26, 159-167.
    • (2012) Phytother. Res , vol.26 , pp. 159-167
    • Zeng, Y.1    Song, J.X.2    Shen, X.C.3
  • 14
    • 84155164808 scopus 로고    scopus 로고
    • Cardiovascular actions and therapeutic potential of tanshinone IIA
    • Gao, S.; Liu, Z.; Li, H.; Little, P.J.; Liu, P.; Xu, S. Cardiovascular actions and therapeutic potential of tanshinone IIA. Atherosclerosis 2012, 220, 3-10.
    • (2012) Atherosclerosis , vol.220 , pp. 3-10
    • Gao, S.1    Liu, Z.2    Li, H.3    Little, P.J.4    Liu, P.5    Xu, S.6
  • 15
    • 79955776388 scopus 로고    scopus 로고
    • Salvianolic acids: Small compounds with multiple mechanisms for cardiovascular protection
    • doi:10.1186/1423-0127-18
    • Ho, J.H.; Hong, C.Y. Salvianolic acids: Small compounds with multiple mechanisms for cardiovascular protection. J. Biomed. Sci. 2011, 18, doi:10.1186/1423-0127-18.
    • (2011) J. Biomed. Sci , pp. 18
    • Ho, J.H.1    Hong, C.Y.2
  • 16
    • 84861231613 scopus 로고    scopus 로고
    • Is danshen (Salvia miltiorrhiza) dripping pill more effective than isosorbide dinitrate in treating angina pectoris? A systematic review of randomized controlled trials
    • Jia, Y.; Huang, F.; Zhang, S.; Leung, S.W. Is danshen (Salvia miltiorrhiza) dripping pill more effective than isosorbide dinitrate in treating angina pectoris? A systematic review of randomized controlled trials. Int. J. Cardiol. 2012, 157, 330-340.
    • (2012) Int. J. Cardiol , vol.157 , pp. 330-340
    • Jia, Y.1    Huang, F.2    Zhang, S.3    Leung, S.W.4
  • 17
    • 1542753421 scopus 로고    scopus 로고
    • Anticancer effect of tanshinone and its mechanisms
    • Yuan, S.L.; Wang, X.J.; Wei, Y.Q. Anticancer effect of tanshinone and its mechanisms. Aizheng 2003, 22, 1363-1366.
    • (2003) Aizheng , vol.22 , pp. 1363-1366
    • Yuan, S.L.1    Wang, X.J.2    Wei, Y.Q.3
  • 20
    • 0023850658 scopus 로고
    • Isolation of an antidermatophytic substrance from the root of Salvia miltiorrhiza
    • Honda, G.; Koezuka, Y.; Tabata, M. Isolation of an antidermatophytic substrance from the root of Salvia miltiorrhiza. Chem. Pharm. Bull. 1988, 36, 408-411.
    • (1988) Chem. Pharm. Bull , vol.36 , pp. 408-411
    • Honda, G.1    Koezuka, Y.2    Tabata, M.3
  • 21
    • 33644822077 scopus 로고    scopus 로고
    • Quality analysis of "whitish" radix Salvia mltiorrhiza in Luanchuan region of Henan province by TLC and HPLC
    • Zhao, R.N.; Xie, P.S.; Yin, W.P.; Lu, P.H.; Yan, Y.Z.; Wang, Z.D. Quality analysis of "whitish" radix Salvia mltiorrhiza in Luanchuan region of Henan province by TLC and HPLC. Chin. Tradit. Herbal. Drugs 2006, 37, 119-122.
    • (2006) Chin. Tradit. Herbal. Drugs , vol.37 , pp. 119-122
    • Zhao, R.N.1    Xie, P.S.2    Yin, W.P.3    Lu, P.H.4    Yan, Y.Z.5    Wang, Z.D.6
  • 22
    • 2042453584 scopus 로고
    • Separation and quantitative determination of seven aqueous depsides in Salvia miltiorrhiza by HPTLC scanning
    • Li, J.; He, L.Y.; Song, W.Z. Separation and quantitative determination of seven aqueous depsides in Salvia miltiorrhiza by HPTLC scanning. Yaoxue Xuebao 1993, 28, 543-547.
    • (1993) Yaoxue Xuebao , vol.28 , pp. 543-547
    • Li, J.1    He, L.Y.2    Song, W.Z.3
  • 23
    • 33646490711 scopus 로고    scopus 로고
    • Fingerprinting of Salvia miltiorrhiza Bunge by thin-layer chromatography scan compared with high speed countercurrent chromatography
    • Gu, M.; Su, Z.; Ouyang, F. Fingerprinting of Salvia miltiorrhiza Bunge by thin-layer chromatography scan compared with high speed countercurrent chromatography. J. Liq. Chromatogr. Relat. Technol. 2006, 29, 1503-1514.
    • (2006) J. Liq. Chromatogr. Relat. Technol , vol.29 , pp. 1503-1514
    • Gu, M.1    Su, Z.2    Ouyang, F.3
  • 24
    • 36048997495 scopus 로고    scopus 로고
    • Improved quality control method for Fufang Danshen preparations through simultaneous determination of phenolic acids, saponins and diterpenoid quinones by HPLC coupled with diode array and evaporative light scattering detectors
    • Wei, Y.J.; Qi, L.W.; Li, P.; Luo, H.W.; Yi, L.; Sheng, L.H. Improved quality control method for Fufang Danshen preparations through simultaneous determination of phenolic acids, saponins and diterpenoid quinones by HPLC coupled with diode array and evaporative light scattering detectors. J. Pharm. Biomed. Anal. 2007, 45, 775-784.
    • (2007) J. Pharm. Biomed. Anal , vol.45 , pp. 775-784
    • Wei, Y.J.1    Qi, L.W.2    Li, P.3    Luo, H.W.4    Yi, L.5    Sheng, L.H.6
  • 25
    • 48049091116 scopus 로고    scopus 로고
    • Simultaneous determination of ten active components in traditional Chinese medicinal products containing both gegen (Pueraria iobata) and danshen (Salvia miltiorrhiza) by high-performance liquid chromatography
    • Chang, Q.; Sun, L.; Zhao, R.H.; Chow, M.S.; Zuo, Z. Simultaneous determination of ten active components in traditional Chinese medicinal products containing both gegen (Pueraria iobata) and danshen (Salvia miltiorrhiza) by high-performance liquid chromatography. Phytochem. Anal. 2008, 19, 368-375.
    • (2008) Phytochem. Anal , vol.19 , pp. 368-375
    • Chang, Q.1    Sun, L.2    Zhao, R.H.3    Chow, M.S.4    Zuo, Z.5
  • 26
    • 34250786764 scopus 로고    scopus 로고
    • Rapid separation and identification of phenolic and diterpenoid constituents from Radix Salvia miltiorrhizae by high-performance liquid chromatography diode-array detection, electrospray ionization time-of-flight mass spectrometry and electrospray ionization quadrupole ion trap mass spectrometry
    • Zhu, Z.; Zhang, H.; Zhao, L.; Dong, X.; Li, X.; Chai, Y.; Zhang, G. Rapid separation and identification of phenolic and diterpenoid constituents from Radix Salvia miltiorrhizae by high-performance liquid chromatography diode-array detection, electrospray ionization time-of-flight mass spectrometry and electrospray ionization quadrupole ion trap mass spectrometry. Rapid Commun. Mass Spectrom. 2007, 21, 1855-1865.
    • (2007) Rapid Commun. Mass Spectrom , vol.21 , pp. 1855-1865
    • Zhu, Z.1    Zhang, H.2    Zhao, L.3    Dong, X.4    Li, X.5    Chai, Y.6    Zhang, G.7
  • 27
    • 65549164870 scopus 로고    scopus 로고
    • Qualitative and quantitative analysis of diterpenoids in Salvia species by liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry
    • Zhou, Y.; Xu, G.; Choi, F.F.; Ding, L.S.; Han, Q.B.; Song, J.Z.; Qiao, C.F.; Zhao, Q.S.; Xu, H.X. Qualitative and quantitative analysis of diterpenoids in Salvia species by liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry. J. Chromatogr. A 2009, 1216, 4847-4858.
    • (2009) J. Chromatogr. A , vol.1216 , pp. 4847-4858
    • Zhou, Y.1    Xu, G.2    Choi, F.F.3    Ding, L.S.4    Han, Q.B.5    Song, J.Z.6    Qiao, C.F.7    Zhao, Q.S.8    Xu, H.X.9
  • 28
    • 0014950995 scopus 로고
    • Countercurrent chromatography: Liquid-liquid partition chromatography without solid support
    • Ito, Y.; Bowman, R.L. Countercurrent chromatography: Liquid-liquid partition chromatography without solid support. Science 1970, 167, 281-283.
    • (1970) Science , vol.167 , pp. 281-283
    • Ito, Y.1    Bowman, R.L.2
  • 29
    • 84946976498 scopus 로고
    • High-speed countercurrent chromatography
    • Ito, Y.; Conway, W.D. High-speed countercurrent chromatography. Crit. Rev. Anal. Chem. 1986, 17, 65-143.
    • (1986) Crit. Rev. Anal. Chem , vol.17 , pp. 65-143
    • Ito, Y.1    Conway, W.D.2
  • 30
    • 51849097663 scopus 로고    scopus 로고
    • Countercurrent separation of natural products
    • Pauli, G.F.; Pro, S.M.; Friesen, J.B. Countercurrent separation of natural products. J. Nat. Prod. 2008, 71, 1489-1508.
    • (2008) J. Nat. Prod , vol.71 , pp. 1489-1508
    • Pauli, G.F.1    Pro, S.M.2    Friesen, J.B.3
  • 31
    • 0034704456 scopus 로고    scopus 로고
    • Separation of tanshinones from Salvia miltiorrhiza Bunge by high-speed counter-current chromatography using stepwise elution
    • Tian, G.; Zhang, Y.; Zhang, T.; Yang, F.; Ito, Y. Separation of tanshinones from Salvia miltiorrhiza Bunge by high-speed counter-current chromatography using stepwise elution. J. Chromatogr. A 2000, 904, 107-111.
    • (2000) J. Chromatogr. A , vol.904 , pp. 107-111
    • Tian, G.1    Zhang, Y.2    Zhang, T.3    Yang, F.4    Ito, Y.5
  • 32
    • 0036470024 scopus 로고    scopus 로고
    • Separation of tanshinones from Salvia miltiorrhiza Bunge by multidimensional counter-current chromatography
    • Tian, G.; Zhang, T.; Zhang, Y.; Ito, Y. Separation of tanshinones from Salvia miltiorrhiza Bunge by multidimensional counter-current chromatography. J. Chromatogr. A 2002, 945, 281-285.
    • (2002) J. Chromatogr. A , vol.945 , pp. 281-285
    • Tian, G.1    Zhang, T.2    Zhang, Y.3    Ito, Y.4
  • 33
    • 0035478823 scopus 로고    scopus 로고
    • The non-mevalonate pathway of isoprenoids: Genes, enzymes and intermediates
    • Rohdich, F.; Kis, K.; Bacher, A.; Eisenreich, W. The non-mevalonate pathway of isoprenoids: Genes, enzymes and intermediates. Curr. Opin. Chem. Biol. 2001, 5, 535-540.
    • (2001) Curr. Opin. Chem. Biol , vol.5 , pp. 535-540
    • Rohdich, F.1    Kis, K.2    Bacher, A.3    Eisenreich, W.4
  • 34
    • 80955181057 scopus 로고    scopus 로고
    • Extraction and preparative purification of tanshinones from Salvia miltiorrhiza Bunge by high-speed counter-current chromatography
    • Sun, A.; Zhang, Y.; Li, A.; Meng, Z.; Liu, R. Extraction and preparative purification of tanshinones from Salvia miltiorrhiza Bunge by high-speed counter-current chromatography. J. Chromatogr. B 2011, 879, 1899-1904.
    • (2011) J. Chromatogr. B , vol.879 , pp. 1899-1904
    • Sun, A.1    Zhang, Y.2    Li, A.3    Meng, Z.4    Liu, R.5
  • 35
    • 84861166372 scopus 로고    scopus 로고
    • Modeling gradient elution in countercurrent chromatography: Efficient separation of tanshinones from Salvia miltiorrhiza Bunge
    • Wu, S.; Wu, D.; Liang, J.; Berthod, A. Modeling gradient elution in countercurrent chromatography: Efficient separation of tanshinones from Salvia miltiorrhiza Bunge. J. Sep. Sci. 2012, 35, 964-976.
    • (2012) J. Sep. Sci , vol.35 , pp. 964-976
    • Wu, S.1    Wu, D.2    Liang, J.3    Berthod, A.4
  • 36
    • 0242405583 scopus 로고    scopus 로고
    • Comparison of high-speed counter-current chromatography and high-performance liquid chromatography on fingerprinting of Chinese traditional medicine
    • Gu, M.; Ouyang, F.; Su, Z. Comparison of high-speed counter-current chromatography and high-performance liquid chromatography on fingerprinting of Chinese traditional medicine. J. Chromatogr. A 2004, 1022, 139-144.
    • (2004) J. Chromatogr. A , vol.1022 , pp. 139-144
    • Gu, M.1    Ouyang, F.2    Su, Z.3
  • 38
    • 0033982773 scopus 로고    scopus 로고
    • Molecular imprinting for drug bioanalysis: A review on the application of imprinted polymers to solid-phase extraction and binding assay
    • Andersson, L.I. Molecular imprinting for drug bioanalysis: A review on the application of imprinted polymers to solid-phase extraction and binding assay. J. Chromatogr. B Biomed. Sci. Appl. 2000, 739, 163-173.
    • (2000) J. Chromatogr. B Biomed. Sci. Appl , vol.739 , pp. 163-173
    • Andersson, L.I.1
  • 39
    • 33845407170 scopus 로고    scopus 로고
    • Molecularly imprinted polymers for the recognition of proteins: The state of the art
    • Bossi, A.; Bonini, F.; Turner, A.P.; Piletsky, S.A. Molecularly imprinted polymers for the recognition of proteins: The state of the art. Biosens. Bioelectron. 2007, 22, 1131-1137.
    • (2007) Biosens. Bioelectron , vol.22 , pp. 1131-1137
    • Bossi, A.1    Bonini, F.2    Turner, A.P.3    Piletsky, S.A.4
  • 41
    • 84863781385 scopus 로고    scopus 로고
    • Rational design of core-shell molecularly imprinted polymer based on computational simulation and Doehlert experimental optimization: Application to the separation of tanshinone IIA from Salvia miltiorrhiza Bunge
    • Jia, X.; Li, H.; Luo, J.; Lu, Q.; Peng, Y.; Shi, L.; Liu, L.; Du, S.; Zhang, G.; Chen, L. Rational design of core-shell molecularly imprinted polymer based on computational simulation and Doehlert experimental optimization: Application to the separation of tanshinone IIA from Salvia miltiorrhiza Bunge. Anal. Bioanal. Chem. 2012, 403, 2691-2703.
    • (2012) Anal. Bioanal. Chem , vol.403 , pp. 2691-2703
    • Jia, X.1    Li, H.2    Luo, J.3    Lu, Q.4    Peng, Y.5    Shi, L.6    Liu, L.7    Du, S.8    Zhang, G.9    Chen, L.10
  • 42
    • 0030605182 scopus 로고    scopus 로고
    • Simultaneous operation of the mevalonate and non-mevalonate pathways in the biosynthesis of isopentenly diphosphate in Streptomyces aeriouvifer
    • Seto, H.; Watanabe, H.; Furihata, K. Simultaneous operation of the mevalonate and non-mevalonate pathways in the biosynthesis of isopentenly diphosphate in Streptomyces aeriouvifer. Tetrahedron Lett. 1996, 37, 7979-7982.
    • (1996) Tetrahedron Lett , vol.37 , pp. 7979-7982
    • Seto, H.1    Watanabe, H.2    Furihata, K.3
  • 43
    • 0030985355 scopus 로고    scopus 로고
    • Terpenoid biosynthesis from 1-deoxy-d-xylulose in higher plants by intramolecular skeletal rearrangement
    • Arigoni, D.; Sagner, S.; Latzel, C.; Eisenreich, W.; Bacher, A.; Zenk, M.H. Terpenoid biosynthesis from 1-deoxy-d-xylulose in higher plants by intramolecular skeletal rearrangement. Proc. Natl. Acad. Sci. USA 1997, 94, 10600-10605.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 10600-10605
    • Arigoni, D.1    Sagner, S.2    Latzel, C.3    Eisenreich, W.4    Bacher, A.5    Zenk, M.H.6
  • 44
    • 0034221342 scopus 로고    scopus 로고
    • Biosynthesis of abscisic acid by the non-mevalonate pathway in plants, and by the mevalonate pathway in Fungi
    • Hirai, N.; Yoshida, R.; Todoroki, Y.; Ohigashi, H. Biosynthesis of abscisic acid by the non-mevalonate pathway in plants, and by the mevalonate pathway in Fungi. Biosci. Biotechnol. Biochem. 2000, 64, 1448-1458.
    • (2000) Biosci. Biotechnol. Biochem , vol.64 , pp. 1448-1458
    • Hirai, N.1    Yoshida, R.2    Todoroki, Y.3    Ohigashi, H.4
  • 45
    • 0032522566 scopus 로고    scopus 로고
    • Mevalonate-derived isopentenyl diphosphate is the biosynthetic precursor of ubiquinone prenyl side chain in tobacco BY-2 cells
    • Disch, A.; Hemmerlin, A.; Bach, T.J.; Rohmer, M. Mevalonate-derived isopentenyl diphosphate is the biosynthetic precursor of ubiquinone prenyl side chain in tobacco BY-2 cells. Biochem. J. 1998, 331, 615-621.
    • (1998) Biochem. J , vol.331 , pp. 615-621
    • Disch, A.1    Hemmerlin, A.2    Bach, T.J.3    Rohmer, M.4
  • 48
    • 77956227486 scopus 로고    scopus 로고
    • Tanshinone biosynthesis in Salvia miltiorrhiza and production in plant tissue cultures
    • Wang, J.W.; Wu, J.Y. Tanshinone biosynthesis in Salvia miltiorrhiza and production in plant tissue cultures. Appl. Microbiol. Biotechnol. 2010, 88, 437-449.
    • (2010) Appl. Microbiol. Biotechnol , vol.88 , pp. 437-449
    • Wang, J.W.1    Wu, J.Y.2
  • 49
    • 0035933854 scopus 로고    scopus 로고
    • 1-Deoxy-d-xylulose-5-phosphate synthase, a limiting enzyme for plastidic isoprenoid biosynthesis in plants
    • Estévez, J.M.; Cantero, A.; Reindl, A.; Reichler, S.; León, P. 1-Deoxy-d-xylulose-5-phosphate synthase, a limiting enzyme for plastidic isoprenoid biosynthesis in plants. J. Biochem. 2001, 276, 22901-22909.
    • (2001) J. Biochem , vol.276 , pp. 22901-22909
    • Estévez, J.M.1    Cantero, A.2    Reindl, A.3    Reichler, S.4    León, P.5
  • 50
    • 0037008188 scopus 로고    scopus 로고
    • Expression and molecular analysis of the Arabidopsis DXR gene encoding 1-Deoxy-d-Xylulose 5-Phosphate reductoisomerase, the first committed enzyme of the 2-C-Methyl-d-Erythritol 4-Phosphate pathway
    • Carretero-Paulet, L.; Ahumada, I.; Cunillera, N.; Rodriguez-Concepción, M.; Ferrer, A.; Boronat, A.; Campos, N. Expression and molecular analysis of the Arabidopsis DXR gene encoding 1-Deoxy-d-Xylulose 5-Phosphate reductoisomerase, the first committed enzyme of the 2-C-Methyl-d-Erythritol 4-Phosphate pathway. Plant Physiol. 2002, 129, 1581-1591.
    • (2002) Plant Physiol , vol.129 , pp. 1581-1591
    • Carretero-Paulet, L.1    Ahumada, I.2    Cunillera, N.3    Rodriguez-Concepción, M.4    Ferrer, A.5    Boronat, A.6    Campos, N.7
  • 51
    • 0033213706 scopus 로고    scopus 로고
    • The discovery of a mevalonate-independent pathway for isoprenoid biosynthesis in bacteria, algae and higher plants
    • Rohmer, M. The discovery of a mevalonate-independent pathway for isoprenoid biosynthesis in bacteria, algae and higher plants. Nat. Prod. Rep. 1999, 16, 565-574.
    • (1999) Nat. Prod. Rep , vol.16 , pp. 565-574
    • Rohmer, M.1
  • 52
    • 0028485650 scopus 로고
    • Molecular structure and enzymatic function of lycopene cyclase from the cyanobacterium Synechococcus sp. strain PCC7942
    • Cunningham, F.X.; Sun, Z.; Chamovitz, D.; Hirschberg, J.; Gantt, E. Molecular structure and enzymatic function of lycopene cyclase from the cyanobacterium Synechococcus sp. strain PCC7942. Plant Cell 1994, 6, 1107-1121.
    • (1994) Plant Cell , vol.6 , pp. 1107-1121
    • Cunningham, F.X.1    Sun, Z.2    Chamovitz, D.3    Hirschberg, J.4    Gantt, E.5
  • 53
    • 0033229957 scopus 로고    scopus 로고
    • Chain-length determination mechanism of isoprenyl diphosphate synthases and implications for molecular evolution
    • Wang, K.; Ohnuma, S. Chain-length determination mechanism of isoprenyl diphosphate synthases and implications for molecular evolution. Trends Biochem. Sci. 1999, 24, 445-451.
    • (1999) Trends Biochem. Sci , vol.24 , pp. 445-451
    • Wang, K.1    Ohnuma, S.2
  • 54
    • 70749152711 scopus 로고    scopus 로고
    • A functional genomics approach to tanshinone biosynthesis provides stereochemical insights
    • Gao, W.; Hillwig, M.L.; Huang, L.; Cui, G.; Wang, X.; Kong, J.; Yang, B.; Peters, R.J. A functional genomics approach to tanshinone biosynthesis provides stereochemical insights. Org. Lett. 2009, 11, 5170-5173.
    • (2009) Org. Lett , vol.11 , pp. 5170-5173
    • Gao, W.1    Hillwig, M.L.2    Huang, L.3    Cui, G.4    Wang, X.5    Kong, J.6    Yang, B.7    Peters, R.J.8
  • 55
    • 0031969630 scopus 로고    scopus 로고
    • Comparative Sstudy of seventeen Salvia plants: Aldose reductase inhibitory activity of water and MeOH extracts and liquid chromatography-mass spectrometry (LC-MS) analysis of water extracts
    • Kasimu, R.; Tanaka, K.; Tezuka, Y.; Gong, Z.N.; Li, J.X.; Basnet, P.; Namba, T.; katota, S. Comparative Sstudy of seventeen Salvia plants: Aldose reductase inhibitory activity of water and MeOH extracts and liquid chromatography-mass spectrometry (LC-MS) analysis of water extracts. Chem. Pharma. Bull. 1998, 46, 500-504.
    • (1998) Chem. Pharma. Bull , vol.46 , pp. 500-504
    • Kasimu, R.1    Tanaka, K.2    Tezuka, Y.3    Gong, Z.N.4    Li, J.X.5    Basnet, P.6    Namba, T.7    Katota, S.8
  • 57
    • 0002026404 scopus 로고
    • Triterpenoids from Salvia przewalskii
    • Wang, N.; Niwa, M.; Luo, H.W. Triterpenoids from Salvia przewalskii. Phytochemistry 1988, 27, 299-301.
    • (1988) Phytochemistry , vol.27 , pp. 299-301
    • Wang, N.1    Niwa, M.2    Luo, H.W.3
  • 58
    • 77950001453 scopus 로고    scopus 로고
    • Distribution of tanshinones in the genus Salvia (family Lamiaceae) from China and its systematic significance
    • Li, M.H.; Peng, Y.; Xiao, P.G. Distribution of tanshinones in the genus Salvia (family Lamiaceae) from China and its systematic significance. J. Syst. Evol. 2010, 48, 118-122.
    • (2010) J. Syst. Evol , vol.48 , pp. 118-122
    • Li, M.H.1    Peng, Y.2    Xiao, P.G.3
  • 59
  • 61
    • 84870716936 scopus 로고    scopus 로고
    • ChemInform abstract: Constituents of roots of Salvia deserta SCHANG. (Xinjiang-Danshen)
    • doi:10.1002/chin.199828287
    • Tezuka, Y.; Kasimu, R.; Li, J.X.; Basnet, P.; Tanaka, K.; Namba, T.; Kadota, S. ChemInform abstract: Constituents of roots of Salvia deserta SCHANG. (Xinjiang-Danshen). ChemInform 1998, 29, doi:10.1002/chin.199828287.
    • (1998) ChemInform , pp. 29
    • Tezuka, Y.1    Kasimu, R.2    Li, J.X.3    Basnet, P.4    Tanaka, K.5    Namba, T.6    Kadota, S.7
  • 62
    • 73949158255 scopus 로고    scopus 로고
    • Analysis of chemical constituents and taxonomic similarity of Salvia species in China using LC/MS
    • Qiao, X.; Zhang, Y.T.; Ye, M.; Wang, B.R.; Han, J.; Guo, D. Analysis of chemical constituents and taxonomic similarity of Salvia species in China using LC/MS. Planta Med. 2009, 75, 1613-1617.
    • (2009) Planta Med , vol.75 , pp. 1613-1617
    • Qiao, X.1    Zhang, Y.T.2    Ye, M.3    Wang, B.R.4    Han, J.5    Guo, D.6
  • 63
    • 0025143165 scopus 로고
    • Structure elucidation and total synthesis of new tanshinones isolated from Salvia miltiorrhiza Bunge (Danshen)
    • Chang, H.M.; Cheng, K.P.; Choang, T.F.; Chow, H.F.; Chui, K.Y.; Hon, P.M.; Tan, F.W.; Yang, Y.; Zhong, Z.P. Structure elucidation and total synthesis of new tanshinones isolated from Salvia miltiorrhiza Bunge (Danshen). J. Org. Chem. 1990, 55, 3537-3543.
    • (1990) J. Org. Chem , vol.55 , pp. 3537-3543
    • Chang, H.M.1    Cheng, K.P.2    Choang, T.F.3    Chow, H.F.4    Chui, K.Y.5    Hon, P.M.6    Tan, F.W.7    Yang, Y.8    Zhong, Z.P.9
  • 65
    • 45449103641 scopus 로고    scopus 로고
    • Antioxidant activity of extracts from leaves and roots of Salvia miltiorrhiza Bunge, S. przewalskii Maxim., and S. verticillata L
    • Matkowski, A.; Zielińska, S.; Oszmiański, J.; Lamer-Zarawska, E. Antioxidant activity of extracts from leaves and roots of Salvia miltiorrhiza Bunge, S. przewalskii Maxim., and S. verticillata L. Bioresour. Technol. 2008, 99, 7892-7896.
    • (2008) Bioresour. Technol , vol.99 , pp. 7892-7896
    • Matkowski, A.1    Zielińska, S.2    Oszmiański, J.3    Lamer-Zarawska, E.4
  • 67
    • 56349130145 scopus 로고    scopus 로고
    • Investigation of Danshen and related medicinal plants in China
    • Li, M.H.; Chen, J.M.; Peng, Y.; Wu, Q.; Xiao, P.G. Investigation of Danshen and related medicinal plants in China. J. Ethnopharmacol. 2008, 120, 419-426.
    • (2008) J. Ethnopharmacol , vol.120 , pp. 419-426
    • Li, M.H.1    Chen, J.M.2    Peng, Y.3    Wu, Q.4    Xiao, P.G.5
  • 68
  • 69
    • 84861580877 scopus 로고    scopus 로고
    • Effects of genotype and environment on active components of Salviae miltiorrhizae by HPLC
    • Sun, P.; He, Y.L.; Zhou, L.L.; Qi, J.J.; Rui, Y.; Li, X.E. Effects of genotype and environment on active components of Salviae miltiorrhizae by HPLC. Asian J. Chem. 2012, 24, 2146-2150.
    • (2012) Asian J. Chem , vol.24 , pp. 2146-2150
    • Sun, P.1    He, Y.L.2    Zhou, L.L.3    Qi, J.J.4    Rui, Y.5    Li, X.E.6
  • 70
    • 77949773623 scopus 로고    scopus 로고
    • The research in production of Danshen in three main cultivations in China
    • Lin, W.; Deng, J.; Lu, M.; Ou, X.; Lin, N.; Yang, G.; Liang, H. The research in production of Danshen in three main cultivations in China. J. Chin. Med. Mater. 2008, 31, 338-340.
    • (2008) J. Chin. Med. Mater , vol.31 , pp. 338-340
    • Lin, W.1    Deng, J.2    Lu, M.3    Ou, X.4    Lin, N.5    Yang, G.6    Liang, H.7
  • 71
    • 77949772779 scopus 로고    scopus 로고
    • Studied of the floral biology, breeding characters of Salvia miltiorrhiza
    • Song, Z.; Wang, J.; Wang, H.; Zhao, F.; Hao, L. Studied of the floral biology, breeding characters of Salvia miltiorrhiza. Acta Hortic. Sin. 2009, 36, 905-910.
    • (2009) Acta Hortic. Sin , vol.36 , pp. 905-910
    • Song, Z.1    Wang, J.2    Wang, H.3    Zhao, F.4    Hao, L.5
  • 72
    • 77956228668 scopus 로고
    • Preliminary investigation of chemical constituents in callus tissue of Danshen
    • Chen, S.; Luo, H.; Yan, S. Preliminary investigation of chemical constituents in callus tissue of Danshen. J. China Pharm. Univ. 1981, 16, 6-8.
    • (1981) J. China Pharm. Univ , vol.16 , pp. 6-8
    • Chen, S.1    Luo, H.2    Yan, S.3
  • 74
    • 10644277954 scopus 로고    scopus 로고
    • Isolation and quantitative analysis of cryptotanshinone, an active quinoid diterpene formed in callus of Salvia miltiorrhiza BUNGE
    • Wu, C.T.; Mulabagal, V.; Nalawade, S.M.; Chen, C.L.; Yang, T.F.; Tsay, H.S. Isolation and quantitative analysis of cryptotanshinone, an active quinoid diterpene formed in callus of Salvia miltiorrhiza BUNGE. Pharm. Bull. 2003, 26, 845-848.
    • (2003) Pharm. Bull , vol.26 , pp. 845-848
    • Wu, C.T.1    Mulabagal, V.2    Nalawade, S.M.3    Chen, C.L.4    Yang, T.F.5    Tsay, H.S.6
  • 75
    • 77956227580 scopus 로고    scopus 로고
    • Clonic reproduction and plant regeneration from blade of Salvia miltiorrhiza Bunge
    • Zhao, J.; Chen, Z.; Wan, J. Clonic reproduction and plant regeneration from blade of Salvia miltiorrhiza Bunge. J. Cent. China Norm. Univ. Nat. Sci. 1999, 33, 108-111.
    • (1999) J. Cent. China Norm. Univ. Nat. Sci , vol.33 , pp. 108-111
    • Zhao, J.1    Chen, Z.2    Wan, J.3
  • 76
    • 49049128854 scopus 로고
    • Production of cryptotanshinone and ferruginol in cultured cells of Salvia miltiorrhiza
    • Tsutomu, N.; Hitoshi, M.; Masao, N.; Hideko, H.; Kaisuke, Y. Production of cryptotanshinone and ferruginol in cultured cells of Salvia miltiorrhiza. Phytochemistry 1983, 22, 721-722.
    • (1983) Phytochemistry , vol.22 , pp. 721-722
    • Tsutomu, N.1    Hitoshi, M.2    Masao, N.3    Hideko, H.4    Kaisuke, Y.5
  • 77
    • 2142716506 scopus 로고
    • Production of ferruginol by cell suspension cultures of Salvia miltiorrhiza
    • Miyasaka, H.; Nasu, M.; Yamamoto, T.; Yoneda, K. Production of ferruginol by cell suspension cultures of Salvia miltiorrhiza. Phytochemistry 1985, 24, 1931-1933.
    • (1985) Phytochemistry , vol.24 , pp. 1931-1933
    • Miyasaka, H.1    Nasu, M.2    Yamamoto, T.3    Yoneda, K.4
  • 78
    • 0347109475 scopus 로고
    • Effect of nutritional factors on cryptotanshinone and ferruginol production by cell suspension cultures of Salvia miltiorrhiza
    • Miyasaka, H.; Nasu, M.; Yamamoto, T.; Shiomi, Y.; Ohno, H.; Endo, Y.; Yoneda, K. Effect of nutritional factors on cryptotanshinone and ferruginol production by cell suspension cultures of Salvia miltiorrhiza. Phytochemistry 1987, 26, 1421-1424.
    • (1987) Phytochemistry , vol.26 , pp. 1421-1424
    • Miyasaka, H.1    Nasu, M.2    Yamamoto, T.3    Shiomi, Y.4    Ohno, H.5    Endo, Y.6    Yoneda, K.7
  • 79
    • 77952890134 scopus 로고    scopus 로고
    • Effects of biotic and abiotic elicitors on cell growth and tanshinone accumulation in Salvia miltiorrhiza cell cultures
    • Zhao, J.L.; Zhou, L.G.; Wu, J.Y. Effects of biotic and abiotic elicitors on cell growth and tanshinone accumulation in Salvia miltiorrhiza cell cultures. Appl. Microbiol. Biotechnol. 2010, 87, 137-144.
    • (2010) Appl. Microbiol. Biotechnol , vol.87 , pp. 137-144
    • Zhao, J.L.1    Zhou, L.G.2    Wu, J.Y.3
  • 80
    • 0001309290 scopus 로고
    • Production of cryptotanshinone and ferruginol by immobilized cultured cells of Salvia miltiorrhiza
    • Miyasaka, H.; Nasu, M.; Yamamoto, T.; Endo, Y.; Yoneda, K. Production of cryptotanshinone and ferruginol by immobilized cultured cells of Salvia miltiorrhiza. Phytochemistry 1986, 25, 1621-1624.
    • (1986) Phytochemistry , vol.25 , pp. 1621-1624
    • Miyasaka, H.1    Nasu, M.2    Yamamoto, T.3    Endo, Y.4    Yoneda, K.5
  • 81
    • 0025662075 scopus 로고
    • Immobilization of callus tissue cells of Salvia miltiorrhiza and the characteristics of their products
    • Yuan, J.; Tao, L.; Xu, J. Immobilization of callus tissue cells of Salvia miltiorrhiza and the characteristics of their products. Chin. J. Biotechnol. 1990, 6, 199-205.
    • (1990) Chin. J. Biotechnol , vol.6 , pp. 199-205
    • Yuan, J.1    Tao, L.2    Xu, J.3
  • 82
    • 0026351570 scopus 로고
    • Tanshinone production in adventitious roots and regenerates of Salvia miltiorrhiza
    • Shimomura, K.; Kitazawa, T.; Okamura, N.; Yagi, A. Tanshinone production in adventitious roots and regenerates of Salvia miltiorrhiza. J. Nat. Prod. 1991, 54, 1583-1587.
    • (1991) J. Nat. Prod , vol.54 , pp. 1583-1587
    • Shimomura, K.1    Kitazawa, T.2    Okamura, N.3    Yagi, A.4
  • 83
    • 77956231418 scopus 로고
    • Genetic engineering in tissue culture of medicinal plants
    • Saito, K. Genetic engineering in tissue culture of medicinal plants. Plant Tissue Cult. Lett. 1993, 10, 1-8.
    • (1993) Plant Tissue Cult. Lett , vol.10 , pp. 1-8
    • Saito, K.1
  • 84
    • 43949174969 scopus 로고
    • Diterpenoid production in hairy root cultures of Salvia miltiorrhiza
    • Zhi, B.H.; Alfermann, A.W. Diterpenoid production in hairy root cultures of Salvia miltiorrhiza. Phytochemistry 1993, 32, 699-703.
    • (1993) Phytochemistry , vol.32 , pp. 699-703
    • Zhi, B.H.1    Alfermann, A.W.2
  • 85
    • 0035793150 scopus 로고    scopus 로고
    • The effect of yeast elicitor on the growth and secondary metabolism of hairy root cultures of Salvia miltiorrhiza
    • Chen, H.; Chena, F.; Chiu, F.C.; Lo, C.M. The effect of yeast elicitor on the growth and secondary metabolism of hairy root cultures of Salvia miltiorrhiza. Enzyme Microb. Technol. 2001, 28, 100-105.
    • (2001) Enzyme Microb. Technol , vol.28 , pp. 100-105
    • Chen, H.1    Chena, F.2    Chiu, F.C.3    Lo, C.M.4
  • 86
    • 10344249948 scopus 로고    scopus 로고
    • + and yeast elicitor
    • + and yeast elicitor. Plant Sci. 2005, 168, 487-491.
    • (2005) Plant Sci , vol.168 , pp. 487-491
    • Ge, X.1    Wu, J.2
  • 87
    • 34247188109 scopus 로고    scopus 로고
    • Effects of methyl jasmonate on accumulation and release of tanshinones in suspension cultures of Salvia miltiorrhiza hairy root
    • Wang, X.; Cui, G.; Huang, L.; Qiu, D. Effects of methyl jasmonate on accumulation and release of tanshinones in suspension cultures of Salvia miltiorrhiza hairy root. Zhongguo Zhongyao Zazhi 2007, 32, 300-302.
    • (2007) Zhongguo Zhongyao Zazhi , vol.32 , pp. 300-302
    • Wang, X.1    Cui, G.2    Huang, L.3    Qiu, D.4
  • 88
    • 79955161144 scopus 로고    scopus 로고
    • Metabolic engineering tanshinone biosynthetic pathway in Salvia miltiorrhiza hairy root cultures
    • Kai, G.; Xu, H.; Zhou, C.; Liao, P.; Xiao, J.; Luo, X.; You, L.; Zhang, L. Metabolic engineering tanshinone biosynthetic pathway in Salvia miltiorrhiza hairy root cultures. Metab. Eng. 2011, 13, 319-327.
    • (2011) Metab. Eng , vol.13 , pp. 319-327
    • Kai, G.1    Xu, H.2    Zhou, C.3    Liao, P.4    Xiao, J.5    Luo, X.6    You, L.7    Zhang, L.8
  • 89
    • 0029444840 scopus 로고
    • Crown gall culture and production of tanshinone in Salvia miltiorrhiza
    • Zhang, Y.; Song, J.; Zhao, B.; Liu, H. Crown gall culture and production of tanshinone in Salvia miltiorrhiza. Chin. J. Biotechnol. 1995, 11, 137-141.
    • (1995) Chin. J. Biotechnol , vol.11 , pp. 137-141
    • Zhang, Y.1    Song, J.2    Zhao, B.3    Liu, H.4
  • 90
    • 0031551915 scopus 로고    scopus 로고
    • Tanshinone production in Ti-transformed Salvia miltiorrhiza cell suspension cultures
    • Chen, H.; Yuan, J.P.; Chen, F.; Zhang, Y.L.; Song, J.Y. Tanshinone production in Ti-transformed Salvia miltiorrhiza cell suspension cultures. J. Biotechnol. 1997, 58, 147-156.
    • (1997) J. Biotechnol , vol.58 , pp. 147-156
    • Chen, H.1    Yuan, J.P.2    Chen, F.3    Zhang, Y.L.4    Song, J.Y.5
  • 91
    • 0034107910 scopus 로고    scopus 로고
    • Effects of yeast elicitor on the growth and secondary metabolism of a high-tanshinone-producing line of the Ti transformed Salvia miltiorrhiza cells in suspension culture
    • Chen, H.; Chen, F. Effects of yeast elicitor on the growth and secondary metabolism of a high-tanshinone-producing line of the Ti transformed Salvia miltiorrhiza cells in suspension culture. Process Biochem. 2000, 35, 837-840.
    • (2000) Process Biochem , vol.35 , pp. 837-840
    • Chen, H.1    Chen, F.2
  • 92
    • 0141834846 scopus 로고    scopus 로고
    • Dynamics of growth and total tanshinones accumulation in crown gall cultures of Salvia miltiorrhiza
    • Song, J.; Qi, J.; Ren, C.; Fu, J.; Zhang, Y. Dynamics of growth and total tanshinones accumulation in crown gall cultures of Salvia miltiorrhiza. Yaoxue Xuebao 2000, 35, 929-931.
    • (2000) Yaoxue Xuebao , vol.35 , pp. 929-931
    • Song, J.1    Qi, J.2    Ren, C.3    Fu, J.4    Zhang, Y.5
  • 93
    • 84857062316 scopus 로고    scopus 로고
    • Tanshinone IIA and tanshinone I production by Trichoderma atroviride D16, an endophytic fungus in Salvia miltiorrhiza
    • Ming, Q.; Han, T.; Li, W.; Zhang, Q.; Zhang, H.; Zheng, C.; Huang, F.; Rahman, K.; Qin, L. Tanshinone IIA and tanshinone I production by Trichoderma atroviride D16, an endophytic fungus in Salvia miltiorrhiza. Phytomedicine 2012, 19, 330-333.
    • (2012) Phytomedicine , vol.19 , pp. 330-333
    • Ming, Q.1    Han, T.2    Li, W.3    Zhang, Q.4    Zhang, H.5    Zheng, C.6    Huang, F.7    Rahman, K.8    Qin, L.9
  • 94
    • 33646774705 scopus 로고    scopus 로고
    • A mechanistic study of the intestinal absorption of cryptotanshinone, the major active Cconstituent of Salvia miltiorrhiza
    • Zhang, J.; Huang, M.; Guan, S.; Bi, H.C.; Pan, Y.; Duan, W.; Chan, S.Y.; Chen, X.; Hong, Y.H.; Bian, J.S.; et al. A mechanistic study of the intestinal absorption of cryptotanshinone, the major active Cconstituent of Salvia miltiorrhiza. J. Pharmacol. Exp. Ther. 2006, 317, 1285-1294.
    • (2006) J. Pharmacol. Exp. Ther , vol.317 , pp. 1285-1294
    • Zhang, J.1    Huang, M.2    Guan, S.3    Bi, H.C.4    Pan, Y.5    Duan, W.6    Chan, S.Y.7    Chen, X.8    Hong, Y.H.9    Bian, J.S.10
  • 95
    • 2342473978 scopus 로고    scopus 로고
    • Determination of tanshinone IIA in rat plasma and the pharmacokinetics by RP-HPLC method
    • Qiao, J.; Hou, P.; Li, Y.; Abliz, Z. Determination of tanshinone IIA in rat plasma and the pharmacokinetics by RP-HPLC method. Yaoxue Xuebao 2003, 38, 368-370.
    • (2003) Yaoxue Xuebao , vol.38 , pp. 368-370
    • Qiao, J.1    Hou, P.2    Li, Y.3    Abliz, Z.4
  • 96
    • 33845254587 scopus 로고    scopus 로고
    • Pharmacokinetics, absorption and tissue distribution of tanshinone IIA solid dispersion
    • Hao, H.; Wang, G.; Cui, N.; Li, J.; Xie, L.; Ding, Z. Pharmacokinetics, absorption and tissue distribution of tanshinone IIA solid dispersion. Planta Med. 2006, 72, 1311-1317.
    • (2006) Planta Med , vol.72 , pp. 1311-1317
    • Hao, H.1    Wang, G.2    Cui, N.3    Li, J.4    Xie, L.5    Ding, Z.6
  • 97
    • 48849099097 scopus 로고    scopus 로고
    • Pharmacokinetic interaction between tanshinones and polyphenolic extracts of Salvia miltinorrhiza Bunge after intravenous administration in rats
    • Guo, Z.J.; Zhang, Y.; Tang, X.; Li, H.; Sun, Q.S. Pharmacokinetic interaction between tanshinones and polyphenolic extracts of Salvia miltinorrhiza Bunge after intravenous administration in rats. Biol. Pharm. Bull. 2008, 31, 1469-1474.
    • (2008) Biol. Pharm. Bull , vol.31 , pp. 1469-1474
    • Guo, Z.J.1    Zhang, Y.2    Tang, X.3    Li, H.4    Sun, Q.S.5
  • 98
    • 34547750321 scopus 로고    scopus 로고
    • Simultaneous determination of danshensu, ferulic acid, cryptotanshinone and tanshinone IIA in rabbit plasma by HPLC and their pharmacokinetic application in danxiongfang
    • Li, X.; Li, X.; Wang, L.; Li, Y.; Xu, Y.; Xue, M. Simultaneous determination of danshensu, ferulic acid, cryptotanshinone and tanshinone IIA in rabbit plasma by HPLC and their pharmacokinetic application in danxiongfang. J. Pharm. Biomed. Anal. 2007, 44, 1106-1112.
    • (2007) J. Pharm. Biomed. Anal , vol.44 , pp. 1106-1112
    • Li, X.1    Li, X.2    Wang, L.3    Li, Y.4    Xu, Y.5    Xue, M.6
  • 99
    • 35148847371 scopus 로고    scopus 로고
    • Pharmacokinetics of cryptotanshinone used alone or combined with danxiongfang in rabbits
    • Li, X.; Wang, L.; Li, Y.; Xu, Y.; Xue, M. Pharmacokinetics of cryptotanshinone used alone or combined with danxiongfang in rabbits. Chin. Pharmacol. Bull. 2007, 23, 1102-1105.
    • (2007) Chin. Pharmacol. Bull , vol.23 , pp. 1102-1105
    • Li, X.1    Wang, L.2    Li, Y.3    Xu, Y.4    Xue, M.5
  • 100
    • 0042228753 scopus 로고    scopus 로고
    • Pharmacokinetics of cryptotanshinone and its metabolite in pigs
    • Xue, M.; Cui, Y.; Wang, H.; Luo, Y.; Zhang, B.; Zhou, Z. Pharmacokinetics of cryptotanshinone and its metabolite in pigs. Acta Pharm. Sin. 1999, 34, 81-84.
    • (1999) Acta Pharm. Sin , vol.34 , pp. 81-84
    • Xue, M.1    Cui, Y.2    Wang, H.3    Luo, Y.4    Zhang, B.5    Zhou, Z.6
  • 101
    • 31344462935 scopus 로고    scopus 로고
    • Simultaneous quantification of cryptotanshinone and its active metabolite tanshinone IIA in plasma by liquid chromatography/tandem mass spectrometry (LC-MS/MS)
    • Hao, H.; Wang, G.; Li, P.; Li, J.; Ding, Z. Simultaneous quantification of cryptotanshinone and its active metabolite tanshinone IIA in plasma by liquid chromatography/tandem mass spectrometry (LC-MS/MS). J. Pharm. Biomed. Anal. 2006, 40, 382-388.
    • (2006) J. Pharm. Biomed. Anal , vol.40 , pp. 382-388
    • Hao, H.1    Wang, G.2    Li, P.3    Li, J.4    Ding, Z.5
  • 102
    • 27644514952 scopus 로고    scopus 로고
    • Determination of cryptotanshinone and its metabolite in rat plasma by liquid chromatography-tandem mass spectrometry
    • Song, M.; Hang, T.J.; Zhang, Z.X.; Du, R.; Chen, J. Determination of cryptotanshinone and its metabolite in rat plasma by liquid chromatography-tandem mass spectrometry. J. Chromatogr. B Anal. Technol. Biomed. Life Sci. 2005, 827, 205-209.
    • (2005) J. Chromatogr. B Anal. Technol. Biomed. Life Sci , vol.827 , pp. 205-209
    • Song, M.1    Hang, T.J.2    Zhang, Z.X.3    Du, R.4    Chen, J.5
  • 103
    • 35748982105 scopus 로고    scopus 로고
    • Effects of the coexisting diterpenoid tanshinones on the pharmacokinetics of cryptotanshinone and tanshinone IIA in rat
    • Song, M.; Hang, T.J.; Zhang, Z.; Chen, H.Y. Effects of the coexisting diterpenoid tanshinones on the pharmacokinetics of cryptotanshinone and tanshinone IIA in rat. Eur. J. Pharm. Sci. 2007, 32, 247-253.
    • (2007) Eur. J. Pharm. Sci , vol.32 , pp. 247-253
    • Song, M.1    Hang, T.J.2    Zhang, Z.3    Chen, H.Y.4
  • 104
    • 26844531763 scopus 로고    scopus 로고
    • Simultaneous determination of tanshinone IIA and cryptotanshinone in rat plasma by liquid chromatography-electrospray ionisation-mass spectrometry
    • Li, J.; Wang, G.; Li, P.; Hao, H. Simultaneous determination of tanshinone IIA and cryptotanshinone in rat plasma by liquid chromatography-electrospray ionisation-mass spectrometry. J. Chromatogr. B Anal. Technol. Biomed. Life Sci. 2005, 826, 26-30.
    • (2005) J. Chromatogr. B Anal. Technol. Biomed. Life Sci , vol.826 , pp. 26-30
    • Li, J.1    Wang, G.2    Li, P.3    Hao, H.4
  • 105
    • 44249104231 scopus 로고    scopus 로고
    • Simultaneous determination of tanshinone I, dihydrotanshinone I, tanshinone IIA and cryptotanshinone in rat plasma by liquid chromatography-tandem mass spectrometry: Application to a pharmacokinetic study of a standardized fraction of Salvia miltiorrhiza, PF2401-SF
    • Park, E.J.; Ji, H.Y.; Kim, N.J.; Song, W.Y.; Kim, Y.H.; Kim, Y.C.; Sohn, D.H.; Lee, H.S. Simultaneous determination of tanshinone I, dihydrotanshinone I, tanshinone IIA and cryptotanshinone in rat plasma by liquid chromatography-tandem mass spectrometry: Application to a pharmacokinetic study of a standardized fraction of Salvia miltiorrhiza, PF2401-SF. Biomed. Chromatogr. 2008, 22, 548-555.
    • (2008) Biomed. Chromatogr , vol.22 , pp. 548-555
    • Park, E.J.1    Ji, H.Y.2    Kim, N.J.3    Song, W.Y.4    Kim, Y.H.5    Kim, Y.C.6    Sohn, D.H.7    Lee, H.S.8
  • 106
    • 77954863532 scopus 로고    scopus 로고
    • Simultaneous determination of danshensu, rosmarinic acid, cryptotanshinone, tanshinone IIA, tanshinone I and dihydrotanshinone I by liquid chromatographic-mass spectrometry and the application to pharmacokinetics in rats
    • Liu, Y.; Li, X.; Li, Y.; Wang, L.; Xue, M. Simultaneous determination of danshensu, rosmarinic acid, cryptotanshinone, tanshinone IIA, tanshinone I and dihydrotanshinone I by liquid chromatographic-mass spectrometry and the application to pharmacokinetics in rats. J. Pharm. Biomed. Anal. 2010, 53, 698-704.
    • (2010) J. Pharm. Biomed. Anal , vol.53 , pp. 698-704
    • Liu, Y.1    Li, X.2    Li, Y.3    Wang, L.4    Xue, M.5
  • 107
    • 84862133432 scopus 로고    scopus 로고
    • Pharmacokinetic comparisons of single herb extract of Fufang Danshen preparation with different combinations of its constituent herbs in rats
    • Yang, S.; Zhang, K.; Lin, X.; Miao, Y.; Meng, L.; Chen, W.; Tang, X. Pharmacokinetic comparisons of single herb extract of Fufang Danshen preparation with different combinations of its constituent herbs in rats. J. Pharm. Biomed. Anal. 2012, 67-68, 77-85.
    • (2012) J. Pharm. Biomed. Anal , vol.67-68 , pp. 77-85
    • Yang, S.1    Zhang, K.2    Lin, X.3    Miao, Y.4    Meng, L.5    Chen, W.6    Tang, X.7
  • 109
    • 79251508628 scopus 로고    scopus 로고
    • Absorption mechanism of tanshinone II A, cryptotanshinone, tanshinone I and tanshinones extract in rat small intestine in vivo
    • Yan, H.; Wu, Q.; Du, S.; Yang, Y.; Zhou, L.; Li, X. Absorption mechanism of tanshinone II A, cryptotanshinone, tanshinone I and tanshinones extract in rat small intestine in vivo. Zhongguo Zhongyao Zazhi 2010, 35, 2917-2922.
    • (2010) Zhongguo Zhongyao Zazhi , vol.35 , pp. 2917-2922
    • Yan, H.1    Wu, Q.2    Du, S.3    Yang, Y.4    Zhou, L.5    Li, X.6
  • 110
    • 53349127298 scopus 로고    scopus 로고
    • Tanshinone I suppresses growth and invasion of human breast cancer cells, MDA-MB-231, through regulation of adhesion molecules
    • Nizamutdinova, I.T.; Lee, G.W.; Lee, J.S.; Cho, M.K.; Son, K.H.; Jeon, S.J.; Kang, S.S.; Kim, Y.S.; Lee, J.H.; Seo, H.G.; et al. Tanshinone I suppresses growth and invasion of human breast cancer cells, MDA-MB-231, through regulation of adhesion molecules. Carcinogenesis 2008, 29, 1885-1892.
    • (2008) Carcinogenesis , vol.29 , pp. 1885-1892
    • Nizamutdinova, I.T.1    Lee, G.W.2    Lee, J.S.3    Cho, M.K.4    Son, K.H.5    Jeon, S.J.6    Kang, S.S.7    Kim, Y.S.8    Lee, J.H.9    Seo, H.G.10
  • 111
    • 0033255368 scopus 로고    scopus 로고
    • Antibacterial activities of cryptotanshinone and dihydrotanshinone I from a medicinal herb, Salvia miltiorrhiza Bunge
    • Lee, D.S.; Lee, S.H.; Noh, J.G.; Hong, S.D. Antibacterial activities of cryptotanshinone and dihydrotanshinone I from a medicinal herb, Salvia miltiorrhiza Bunge. Biosci. Biotechnol. Biochem. 1999, 63, 2236-2239.
    • (1999) Biosci. Biotechnol. Biochem , vol.63 , pp. 2236-2239
    • Lee, D.S.1    Lee, S.H.2    Noh, J.G.3    Hong, S.D.4
  • 112
    • 70349581629 scopus 로고    scopus 로고
    • Effect of sodium tanshinone II A sulfonate on the activity of CYP1A2 in healthy volunteers
    • Chen, Y.; Tu, J.H.; He, Y.J.; Zhang, W.; Wang, G.; Tan, Z.R.; Zhou, G.; Fan, L.; Zhou, H.H. Effect of sodium tanshinone II A sulfonate on the activity of CYP1A2 in healthy volunteers. Xenobiotica 2009, 39, 508-513.
    • (2009) Xenobiotica , vol.39 , pp. 508-513
    • Chen, Y.1    Tu, J.H.2    He, Y.J.3    Zhang, W.4    Wang, G.5    Tan, Z.R.6    Zhou, G.7    Fan, L.8    Zhou, H.H.9
  • 114
    • 0000134154 scopus 로고
    • Antioxidative components of tanshen (Salvia miltiorhiza Bung)
    • Zhang, K.Q.; Bao, Y.; Wu, P.; Rosen, R.T.; Ho, C.T. Antioxidative components of tanshen (Salvia miltiorhiza Bung). J. Agric. Food Chem. 1990, 38, 1194-1197.
    • (1990) J. Agric. Food Chem , vol.38 , pp. 1194-1197
    • Zhang, K.Q.1    Bao, Y.2    Wu, P.3    Rosen, R.T.4    Ho, C.T.5
  • 115
    • 0033825175 scopus 로고    scopus 로고
    • Inhibition of interleukin-12 and interferon-gamma production in immune cells by tanshinones from Salvia miltiorrhiza
    • Kang, B.Y.; Chung, S.W.; Kim, S.H.; Ryu, S.Y.; Kim, T.S. Inhibition of interleukin-12 and interferon-gamma production in immune cells by tanshinones from Salvia miltiorrhiza. Immunopharmacology 2000, 49, 355-361.
    • (2000) Immunopharmacology , vol.49 , pp. 355-361
    • Kang, B.Y.1    Chung, S.W.2    Kim, S.H.3    Ryu, S.Y.4    Kim, T.S.5
  • 116
    • 77956231164 scopus 로고    scopus 로고
    • A novel compound modified from tanshinone inhibits tumor growth in vivo via activation of the intrinsic apoptotic pathway
    • Tian, H.L.; Yu, T.; Xu, N.N.; Feng, C.; Zhou, L.Y.; Luo, H.W.; Chang, D.C.; Le, X.F.; Luo, K.Q. A novel compound modified from tanshinone inhibits tumor growth in vivo via activation of the intrinsic apoptotic pathway. Cancer Lett. 2010, 297, 18-30.
    • (2010) Cancer Lett , vol.297 , pp. 18-30
    • Tian, H.L.1    Yu, T.2    Xu, N.N.3    Feng, C.4    Zhou, L.Y.5    Luo, H.W.6    Chang, D.C.7    Le, X.F.8    Luo, K.Q.9
  • 117
    • 9844253447 scopus 로고
    • Antioxidant activity of quinones extracted from tanshen (Salvia miltiorrhiza Bunge)
    • Weng, X.C.; Gordon, M.H. Antioxidant activity of quinones extracted from tanshen (Salvia miltiorrhiza Bunge). J. Agric. Food Chem. 1992, 40, 1331-1336.
    • (1992) J. Agric. Food Chem , vol.40 , pp. 1331-1336
    • Weng, X.C.1    Gordon, M.H.2
  • 118
    • 24644463195 scopus 로고    scopus 로고
    • Preparation and pharmacokinetic evaluation of Tashinone IIA solid lipid nanoparticles
    • Liu, J.; Zhu, J.; Du, Z.; Qin, B. Preparation and pharmacokinetic evaluation of Tashinone IIA solid lipid nanoparticles. Drug Dev. Ind. Pharm. 2005, 31, 551-556.
    • (2005) Drug Dev. Ind. Pharm , vol.31 , pp. 551-556
    • Liu, J.1    Zhu, J.2    Du, Z.3    Qin, B.4
  • 119
    • 76249133107 scopus 로고    scopus 로고
    • Stealth tanshinone IIA-loaded solid lipid nanoparticles: Effects of poloxamer 188 coating on in vitro phagocytosis and in vivo pharmacokinetics in rats
    • Zhang, W.; Liu, J.; Liu, X.; Chen, Z. Stealth tanshinone IIA-loaded solid lipid nanoparticles: Effects of poloxamer 188 coating on in vitro phagocytosis and in vivo pharmacokinetics in rats. Yaoxue Xuebao 2009, 44, 1421-1428.
    • (2009) Yaoxue Xuebao , vol.44 , pp. 1421-1428
    • Zhang, W.1    Liu, J.2    Liu, X.3    Chen, Z.4
  • 120
    • 56349115456 scopus 로고    scopus 로고
    • Novel polymeric nanoparticles containing tanshinone IIA for the treatment of hepatoma
    • Li, Q.; Wang, Y.; Feng, N.; Fan, Z.; Sun, J.; Nan, Y. Novel polymeric nanoparticles containing tanshinone IIA for the treatment of hepatoma. J. Drug Targeting 2008, 16, 725-732.
    • (2008) J. Drug Targeting , vol.16 , pp. 725-732
    • Li, Q.1    Wang, Y.2    Feng, N.3    Fan, Z.4    Sun, J.5    Nan, Y.6
  • 121
    • 77954817405 scopus 로고    scopus 로고
    • Preparation and enhanced oral bioavailability of cryptotanshinone-loaded solid lipid nanoparticles
    • Hu, L.; Xing, Q.; Meng, J.; Shang, C. Preparation and enhanced oral bioavailability of cryptotanshinone-loaded solid lipid nanoparticles. AAPS PharmSciTech 2010, 11, 582-587.
    • (2010) AAPS PharmSciTech , vol.11 , pp. 582-587
    • Hu, L.1    Xing, Q.2    Meng, J.3    Shang, C.4
  • 122
    • 1942470488 scopus 로고    scopus 로고
    • Cyclodextrins and their uses: A review
    • Del Valle, E.M.M. Cyclodextrins and their uses: A review. Process Biochem. 2004, 39, 1033-1046.
    • (2004) Process Biochem , vol.39 , pp. 1033-1046
    • De Valle, E.M.M.1
  • 123
    • 9544241323 scopus 로고    scopus 로고
    • Preparation and study on the inclusion complexes of two tanshinone compounds with β-cyclodextrin
    • Yuexian, F.; Junfen, L.; Chuan, D. Preparation and study on the inclusion complexes of two tanshinone compounds with β-cyclodextrin. Spectrochim. Acta Part A 2005, 61, 135-140.
    • (2005) Spectrochim. Acta Part A , vol.61 , pp. 135-140
    • Yuexian, F.1    Junfen, L.2    Chuan, D.3
  • 124
    • 59149096511 scopus 로고    scopus 로고
    • Growth inhibition and apoptosis induction by tanshinone I in human colon cancer Colo 205 cells
    • Su, C.C.; Chen, G.W.; Lin, J.G. Growth inhibition and apoptosis induction by tanshinone I in human colon cancer Colo 205 cells. Int. J. Mol. Med. 2008, 22, 613-618.
    • (2008) Int. J. Mol. Med , vol.22 , pp. 613-618
    • Su, C.C.1    Chen, G.W.2    Lin, J.G.3
  • 125
    • 84870716542 scopus 로고    scopus 로고
    • The effect of Tanshinone I on proliferation and apoptosis of human gastric adenocarcinoma cell line SGC-7901
    • Zhou, X.; Jia, M.; Zhang, Y. The effect of Tanshinone I on proliferation and apoptosis of human gastric adenocarcinoma cell line SGC-7901. J. Mod. Oncol. 2011, 19, 23-27.
    • (2011) J. Mod. Oncol , vol.19 , pp. 23-27
    • Zhou, X.1    Jia, M.2    Zhang, Y.3
  • 126
    • 54849187400 scopus 로고    scopus 로고
    • Tanshinone I effectively induces apoptosis in estrogen receptor-positive (MCF-7) and estrogen receptor-negative (MDA-MB-231) breast cancer cells
    • Nizamutdinova, I.T.; Lee, G.W.; Son, K.H.; Jeon, S.J.; Kang, S.S.; Kim, Y.S.; Lee, J.H.; Seo, H.G.; Chang, K.C.; Kim, H.J. Tanshinone I effectively induces apoptosis in estrogen receptor-positive (MCF-7) and estrogen receptor-negative (MDA-MB-231) breast cancer cells. Int. J. Oncol. 2008, 33, 485-491.
    • (2008) Int. J. Oncol , vol.33 , pp. 485-491
    • Nizamutdinova, I.T.1    Lee, G.W.2    Son, K.H.3    Jeon, S.J.4    Kang, S.S.5    Kim, Y.S.6    Lee, J.H.7    Seo, H.G.8    Chang, K.C.9    Kim, H.J.10
  • 127
    • 84859248400 scopus 로고    scopus 로고
    • Tanshinones inhibit the growth of breast cancer cells through epigenetic modification of Aurora A expression and function
    • doi: 10.1371/journal.pone.0033656
    • Gong, Y.; Li, Y.; Abdolmaleky, H.M.; Li, L.; Zhou, J.R. Tanshinones inhibit the growth of breast cancer cells through epigenetic modification of Aurora A expression and function. PLoS One 2012, 7, doi: 10.1371/journal.pone.0033656.
    • (2012) PLoS One , pp. 7
    • Gong, Y.1    Li, Y.2    Abdolmaleky, H.M.3    Li, L.4    Zhou, J.R.5
  • 128
    • 84870702113 scopus 로고    scopus 로고
    • Study on the anti-tumor effect and mechanism of tanshinone I
    • Zheng, G.; Li, Z. Study on the anti-tumor effect and mechanism of tanshinone I. J. Prac. Oncol. 2005, 94, 33-35.
    • (2005) J. Prac. Oncol , vol.94 , pp. 33-35
    • Zheng, G.1    Li, Z.2
  • 129
    • 79959767855 scopus 로고    scopus 로고
    • Bioactive tanshinones in Salvia miltiorrhiza inhibit the growth of prostate cancer cells in vitro and in mice
    • Gong, Y.; Li, Y.; Lu, Y.; Li, L.; Abdolmaleky, H.; Blackburn, G.L.; Zhou, J.R. Bioactive tanshinones in Salvia miltiorrhiza inhibit the growth of prostate cancer cells in vitro and in mice. Int. J. Cancer 2011, 129, 1042-1052.
    • (2011) Int. J. Cancer , vol.129 , pp. 1042-1052
    • Gong, Y.1    Li, Y.2    Lu, Y.3    Li, L.4    Abdolmaleky, H.5    Blackburn, G.L.6    Zhou, J.R.7
  • 130
    • 84879463275 scopus 로고    scopus 로고
    • Bioactive tanshinone I inhibits the growth of lung cancer in part via downregulation of Aurora A function
    • 10.1002/mc.21888
    • Li, Y.; Gong, Y.; Li, L.; Abdolmaleky, H.M.; Zhou, J.R. Bioactive tanshinone I inhibits the growth of lung cancer in part via downregulation of Aurora A function. Mol. Carcinog. 2012, doi:10.1002/mc.21888.
    • (2012) Mol. Carcinog
    • Li, Y.1    Gong, Y.2    Li, L.3    Abdolmaleky, H.M.4    Zhou, J.R.5
  • 131
    • 77956975737 scopus 로고    scopus 로고
    • Inactivation of PI3k/Akt signaling pathway and activation of caspase-3 are involved in tanshinone I-induced apoptosis in myeloid leukemia cells in vitro
    • Liu, J.J.; Liu, W.D.; Yang, H.Z.; Zhang, Y.; Fang, Z.G.; Liu, P.Q.; Lin, D.J.; Xiao, R.Z.; Hu, Y.; Wang, C.Z.; et al. Inactivation of PI3k/Akt signaling pathway and activation of caspase-3 are involved in tanshinone I-induced apoptosis in myeloid leukemia cells in vitro. Ann. Hematol. 2010, 89, 1089-1097.
    • (2010) Ann. Hematol , vol.89 , pp. 1089-1097
    • Liu, J.J.1    Liu, W.D.2    Yang, H.Z.3    Zhang, Y.4    Fang, Z.G.5    Liu, P.Q.6    Lin, D.J.7    Xiao, R.Z.8    Hu, Y.9    Wang, C.Z.10
  • 132
    • 84859903322 scopus 로고    scopus 로고
    • Activation of p53 signaling and inhibition of androgen receptor mediate tanshinone IIA induced G1 arrest in LNCaP prostate cancer cells
    • Won, S.H.; Lee, H.J.; Jeong, S.J.; Lu, J.; Kim, S.H. Activation of p53 signaling and inhibition of androgen receptor mediate tanshinone IIA induced G1 arrest in LNCaP prostate cancer cells. Phytother. Res. 2012, 26, 669-674.
    • (2012) Phytother. Res , vol.26 , pp. 669-674
    • Won, S.H.1    Lee, H.J.2    Jeong, S.J.3    Lu, J.4    Kim, S.H.5
  • 133
    • 78249235878 scopus 로고    scopus 로고
    • Tanshinone IIA induces mitochondria dependent apoptosis in prostate cancer cells in association with an inhibition of phosphoinositide 3-kinase/AKT pathway
    • Won, S.H.; Lee, H.J.; Jeong, S.J.; Lee, E.O.; Jung, D.B.; Shin, J.M.; Kwon, T.R.; Yun, S.M.; Lee, M.H.; Choi, S.H.; et al. Tanshinone IIA induces mitochondria dependent apoptosis in prostate cancer cells in association with an inhibition of phosphoinositide 3-kinase/AKT pathway. Biol. Pharm. Bull. 2010, 33, 1828-1834.
    • (2010) Biol. Pharm. Bull , vol.33 , pp. 1828-1834
    • Won, S.H.1    Lee, H.J.2    Jeong, S.J.3    Lee, E.O.4    Jung, D.B.5    Shin, J.M.6    Kwon, T.R.7    Yun, S.M.8    Lee, M.H.9    Choi, S.H.10
  • 134
    • 53049099464 scopus 로고    scopus 로고
    • Tanshinone IIA inhibits human breast cancer cells through increased Bax to Bcl-xL ratios
    • Su, C.C.; Lin, Y.H. Tanshinone IIA inhibits human breast cancer cells through increased Bax to Bcl-xL ratios. Int. J. Mol. Med. 2008, 22, 357-361.
    • (2008) Int. J. Mol. Med , vol.22 , pp. 357-361
    • Su, C.C.1    Lin, Y.H.2
  • 135
    • 84863281854 scopus 로고    scopus 로고
    • Tanshinone IIA inhibits BT-20 human breast cancer cell proliferation through increasing caspase 12, GADD153 and phospho-p38 protein expression
    • Yan, M.Y.; Chien, S.Y.; Kuo, S.J.; Chen, D.R.; Su, C.C. Tanshinone IIA inhibits BT-20 human breast cancer cell proliferation through increasing caspase 12, GADD153 and phospho-p38 protein expression. Int. J. Mol. Med. 2012, 29, 855-863.
    • (2012) Int. J. Mol. Med , vol.29 , pp. 855-863
    • Yan, M.Y.1    Chien, S.Y.2    Kuo, S.J.3    Chen, D.R.4    Su, C.C.5
  • 136
    • 23244463302 scopus 로고    scopus 로고
    • Potential anticancer activity of tanshinone IIA against human breast cancer
    • Wang, X.; Wei, Y.; Yuan, S.; Liu, G.; Lu, Y.; Zhang, J.; Wang, W. Potential anticancer activity of tanshinone IIA against human breast cancer. Int. J. Cancer 2005, 116, 799-807.
    • (2005) Int. J. Cancer , vol.116 , pp. 799-807
    • Wang, X.1    Wei, Y.2    Yuan, S.3    Liu, G.4    Lu, Y.5    Zhang, J.6    Wang, W.7
  • 137
    • 70350765325 scopus 로고    scopus 로고
    • Experimental study of the anti-cancer mechanism of tanshinone IIA against human breast cancer
    • Lu, Q.; Zhang, P.; Zhang, X.; Chen, J. Experimental study of the anti-cancer mechanism of tanshinone IIA against human breast cancer. Int. J. Mol. Med. 2009, 24, 773-780.
    • (2009) Int. J. Mol. Med , vol.24 , pp. 773-780
    • Lu, Q.1    Zhang, P.2    Zhang, X.3    Chen, J.4
  • 138
    • 76249131776 scopus 로고    scopus 로고
    • A study on the effect of Tanshinone IIA against human breast cancer in vivo
    • Zhang, X.; Zhang, P.; Chen, J.; Lu, Q. A study on the effect of Tanshinone IIA against human breast cancer in vivo. Sichuan Daxue Xuebao Yixueban 2010, 41, 62-67.
    • (2010) Sichuan Daxue Xuebao Yixueban , vol.41 , pp. 62-67
    • Zhang, X.1    Zhang, P.2    Chen, J.3    Lu, Q.4
  • 139
    • 84870691548 scopus 로고    scopus 로고
    • Reversal of the malignant phenotypes by tanshinone IIA in human breast cancer MCF-7 cell lines and its molecular mechanism
    • Du, R.; Zheng, H.; Wang, Y.; Yuan, S. Reversal of the malignant phenotypes by tanshinone IIA in human breast cancer MCF-7 cell lines and its molecular mechanism. West China West China J. Pharm. Sci. 2009, 24, 42-45.
    • (2009) West China West China J. Pharm. Sci , vol.24 , pp. 42-45
    • Du, R.1    Zheng, H.2    Wang, Y.3    Yuan, S.4
  • 140
    • 34249852939 scopus 로고    scopus 로고
    • Growth inhibition and multidrug resistance-reversing effect of Tanshinone IIA on human breast cancer cell with estrogen receptor negative
    • Jing, J.; Zheng, H.; Wang, J.; Lin, P.; Zhang, J.; Xiong, Z.; Wu, Y.; Ren, J.; Yang, H.; Wang, X. Growth inhibition and multidrug resistance-reversing effect of Tanshinone IIA on human breast cancer cell with estrogen receptor negative. Sichuan Daxue Xuebao Yixueban 2007, 38, 391-395.
    • (2007) Sichuan Daxue Xuebao Yixueban , vol.38 , pp. 391-395
    • Jing, J.1    Zheng, H.2    Wang, J.3    Lin, P.4    Zhang, J.5    Xiong, Z.6    Wu, Y.7    Ren, J.8    Yang, H.9    Wang, X.10
  • 141
    • 65449179230 scopus 로고    scopus 로고
    • Tanshinone IIA down-regulates the protein expression of ErbB-2 and up-regulates TNF-alpha in colon cancer cells in vitro and in vivo
    • Su, C.C.; Lin, Y.H. Tanshinone IIA down-regulates the protein expression of ErbB-2 and up-regulates TNF-alpha in colon cancer cells in vitro and in vivo. Int. J. Mol. Med. 2008, 22, 847-851.
    • (2008) Int. J. Mol. Med , vol.22 , pp. 847-851
    • Su, C.C.1    Lin, Y.H.2
  • 142
    • 73649126883 scopus 로고    scopus 로고
    • Tanshinone IIA induces apoptosis in human lung cancer A549 cells through the induction of reactive oxygen species and decreasing the mitochondrial membrane potential
    • Chiu, T.L.; Su, C.C. Tanshinone IIA induces apoptosis in human lung cancer A549 cells through the induction of reactive oxygen species and decreasing the mitochondrial membrane potential. Int. J. Mol. Med. 2010, 25, 231-236.
    • (2010) Int. J. Mol. Med , vol.25 , pp. 231-236
    • Chiu, T.L.1    Su, C.C.2
  • 143
    • 77956671599 scopus 로고    scopus 로고
    • Tanshinone IIA may inhibit the growth of small cell lung cancer H146 cells by up-regulating the Bax/Bcl-2 ratio and decreasing mitochondrial membrane potential
    • Cheng, C.Y.; Su, C.C. Tanshinone IIA may inhibit the growth of small cell lung cancer H146 cells by up-regulating the Bax/Bcl-2 ratio and decreasing mitochondrial membrane potential. Mol. Med. Rep. 2010, 3, 645-650.
    • (2010) Mol. Med. Rep , vol.3 , pp. 645-650
    • Cheng, C.Y.1    Su, C.C.2
  • 144
    • 78651284819 scopus 로고    scopus 로고
    • Effect of tanshinone IIA on proliferation and apoptosis of human lung cancer cell line A549/CDDP
    • Wang, J.; Zhou, X.; Yuan, H.; Huang, X.; Wu, L.; Zhang, F.; Liu, X. Effect of tanshinone IIA on proliferation and apoptosis of human lung cancer cell line A549/CDDP. J. Prac. Oncol. 2010, 25, 684-688.
    • (2010) J. Prac. Oncol , vol.25 , pp. 684-688
    • Wang, J.1    Zhou, X.2    Yuan, H.3    Huang, X.4    Wu, L.5    Zhang, F.6    Liu, X.7
  • 145
    • 79952319217 scopus 로고    scopus 로고
    • Apoptosis inducing effect of Tanshinone IIA onhuman lung adenocarcinoma A549 cells
    • Dai, Z.; Shi, J.; Wu, Q.; Yu, L.; Xu, Q. Apoptosis inducing effect of Tanshinone IIA onhuman lung adenocarcinoma A549 cells. Chin. Pharmacol. Bull. 2010, 26, 111-114.
    • (2010) Chin. Pharmacol. Bull , vol.26 , pp. 111-114
    • Dai, Z.1    Shi, J.2    Wu, Q.3    Yu, L.4    Xu, Q.5
  • 146
    • 84856219184 scopus 로고    scopus 로고
    • Tanshinone IIA activates calcium-dependent apoptosis signaling pathway in human hepatoma cells
    • Dai, Z.K.; Qin, J.K.; Huang, J.E.; Luo, Y.; Xu, Q.; Zhao, H.L. Tanshinone IIA activates calcium-dependent apoptosis signaling pathway in human hepatoma cells. J. Nat. Med. 2012, 66, 192-201.
    • (2012) J. Nat. Med , vol.66 , pp. 192-201
    • Dai, Z.K.1    Qin, J.K.2    Huang, J.E.3    Luo, Y.4    Xu, Q.5    Zhao, H.L.6
  • 147
    • 77956671604 scopus 로고    scopus 로고
    • Tanshinone IIA inhibits Hep-J5 cells by increasing calreticulin, caspase 12 and GADD153 protein expression
    • Cheng, C.Y.; Su, C.C. Tanshinone IIA inhibits Hep-J5 cells by increasing calreticulin, caspase 12 and GADD153 protein expression. Int. J. Mol. Med. 2010, 26, 379-385.
    • (2010) Int. J. Mol. Med , vol.26 , pp. 379-385
    • Cheng, C.Y.1    Su, C.C.2
  • 148
    • 84855236222 scopus 로고    scopus 로고
    • Tanshinone IIA inhibits human hepatocellular carcinoma J5 cell growth by increasing Bax and caspase 3 and decreasing CD31 expression in vivo
    • Chien, S.Y.; Kuo, S.J.; Chen, Y.L.; Chen, D.R.; Cheng, C.; Su, C.C. Tanshinone IIA inhibits human hepatocellular carcinoma J5 cell growth by increasing Bax and caspase 3 and decreasing CD31 expression in vivo. Mol. Med. Rep. 2012, 5, 282-286.
    • (2012) Mol. Med. Rep , vol.5 , pp. 282-286
    • Chien, S.Y.1    Kuo, S.J.2    Chen, Y.L.3    Chen, D.R.4    Cheng, C.5    Su, C.C.6
  • 149
    • 36849061154 scopus 로고    scopus 로고
    • Cytotoxicity of major tanshinones isolated from Danshen (Salvia miltiorrhiza) on HepG2 cells in relation to glutathione perturbation
    • Lee, W.Y.; Chiu, L.C.; Yeung, J.H. Cytotoxicity of major tanshinones isolated from Danshen (Salvia miltiorrhiza) on HepG2 cells in relation to glutathione perturbation. Food Chem. Toxicol. 2008, 46, 328-338.
    • (2008) Food Chem. Toxicol , vol.46 , pp. 328-338
    • Lee, W.Y.1    Chiu, L.C.2    Yeung, J.H.3
  • 150
    • 4043125279 scopus 로고    scopus 로고
    • Growth inhibition and apoptosis induction of tanshinone II-A on human hepatocellular carcinoma cells
    • Yuan, S.L.; Wei, Y.Q.; Wang, X.J.; Xiao, F.; Li, S.F.; Zhang, J. Growth inhibition and apoptosis induction of tanshinone II-A on human hepatocellular carcinoma cells. World J. Gastroenterol. 2004, 10, 2024-2028.
    • (2004) World J. Gastroenterol , vol.10 , pp. 2024-2028
    • Yuan, S.L.1    Wei, Y.Q.2    Wang, X.J.3    Xiao, F.4    Li, S.F.5    Zhang, J.6
  • 151
    • 2142858752 scopus 로고    scopus 로고
    • Effect of tanshinone IIA on the growth behavior of human hepatoma cell line BEL-7402 in vitro and its mechanism
    • Tang, Z.Z.; Tang, Y.; Fu, L.B. Effect of tanshinone IIA on the growth behavior of human hepatoma cell line BEL-7402 in vitro and its mechanism. Diyi Junyi Daxue Xuebao 2003, 23, 595-597, 601.
    • Diyi Junyi Daxue Xuebao 2003, 23 , vol.595-597 , pp. 601
    • Tang, Z.Z.1    Tang, Y.2    Fu, L.B.3
  • 152
    • 77950365786 scopus 로고    scopus 로고
    • Effect of Tanshinone IIA on expression of EGF and EGFR in hepatocellular carcinoma cell line SMMC-7721
    • Zhai, X.; He, S.; Ren, M.; Chen, J.; Wang, Z.; Han, M.; Hou, H. Effect of Tanshinone IIA on expression of EGF and EGFR in hepatocellular carcinoma cell line SMMC-7721. Zhejiang Daxue Xuebao Yixueban 2009, 38, 163-169.
    • (2009) Zhejiang Daxue Xuebao Yixueban , vol.38 , pp. 163-169
    • Zhai, X.1    He, S.2    Ren, M.3    Chen, J.4    Wang, Z.5    Han, M.6    Hou, H.7
  • 154
    • 84870714356 scopus 로고    scopus 로고
    • The effect of three composition of Salviae miltiorrhizae on growth of Bel-7402 and peripheral blood stem cells
    • Li, Q.; Li, C.; Huang, Z.; Luo, Y.; Wei, G.; Mei, G. The effect of three composition of Salviae miltiorrhizae on growth of Bel-7402 and peripheral blood stem cells. Prac. J. Cancer 2001, 16, 467-468.
    • (2001) Prac. J. Cancer , vol.16 , pp. 467-468
    • Li, Q.1    Li, C.2    Huang, Z.3    Luo, Y.4    Wei, G.5    Mei, G.6
  • 155
    • 84855752580 scopus 로고    scopus 로고
    • Tanshinone IIA induces growth inhibition and apoptosis in gastric cancer in vitro and in vivo
    • Chen, J.; Shi, D.Y.; Liu, S.L.; Zhong, L. Tanshinone IIA induces growth inhibition and apoptosis in gastric cancer in vitro and in vivo. Oncol. Rep. 2012, 27, 523-528.
    • (2012) Oncol. Rep , vol.27 , pp. 523-528
    • Chen, J.1    Shi, D.Y.2    Liu, S.L.3    Zhong, L.4
  • 156
    • 38849086189 scopus 로고    scopus 로고
    • Growth-inhibiting and apoptosis-inducing effects of Tanshinone II A on human gastric carcinoma cells
    • Dong, X.; Dong, J.; Peng, G. Growth-inhibiting and apoptosis-inducing effects of Tanshinone II A on human gastric carcinoma cells. J. Huazhong Univ. Sci. Technol. Med. Sci. 2007, 27, 706-709.
    • (2007) J. Huazhong Univ. Sci. Technol. Med. Sci , vol.27 , pp. 706-709
    • Dong, X.1    Dong, J.2    Peng, G.3
  • 157
    • 36048983489 scopus 로고    scopus 로고
    • The effect of Tanshinone IIA on proliferation and apoptosis of human gastric adenocarcinoma cell line SGC-7901
    • Zhou, X.; Song, Z.; Wang, X. The effect of Tanshinone IIA on proliferation and apoptosis of human gastric adenocarcinoma cell line SGC-7901. J. Xi'an Jiaotong Univ. (Med. Sci.) 2007, 28, 511-513, 525.
    • J. Xi'an Jiaotong Univ. (Med. Sci.) 2007, 28 , vol.511-513 , pp. 525
    • Zhou, X.1    Song, Z.2    Wang, X.3
  • 158
    • 84907092128 scopus 로고    scopus 로고
    • Anticancer effect of Tanshinone IIA on human gastric carcinoma MGC-803 cells
    • Dai, Z.; Huang, J.; Luo, W.; Xu, Q. Anticancer effect of Tanshinone IIA on human gastric carcinoma MGC-803 cells. Chin. Pharm. J. 2011, 46, 1491-1495.
    • (2011) Chin. Pharm. J , vol.46 , pp. 1491-1495
    • Dai, Z.1    Huang, J.2    Luo, W.3    Xu, Q.4
  • 159
    • 34248660831 scopus 로고    scopus 로고
    • Apoptosis of SGC7901 gastric cancer cell induced by Tanshinone IIA and the primary mechanisms
    • Chen, J.; Zhong, L.; Qiang, L.; Hua, Z.; Lin, G.; Liu, S. Apoptosis of SGC7901 gastric cancer cell induced by Tanshinone IIA and the primary mechanisms. Fudan Univ. J. Med. Sci. 2007, 34, 57-61.
    • (2007) Fudan Univ. J. Med. Sci , vol.34 , pp. 57-61
    • Chen, J.1    Zhong, L.2    Qiang, L.3    Hua, Z.4    Lin, G.5    Liu, S.6
  • 160
    • 79957715055 scopus 로고    scopus 로고
    • Tanshinone IIA induces apoptosis of pancreatic cancer cells via the SAPK/JNK signal pathway
    • Wang, Y.; Li, Q.; Fan, Z.; Wang, Y.; Qiu, Y.; Jin, B.; Chen, X.; Yin, P. Tanshinone IIA induces apoptosis of pancreatic cancer cells via the SAPK/JNK signal pathway. World Chin. J. Digestol. 2011, 19, 1028-1033.
    • (2011) World Chin. J. Digestol , vol.19 , pp. 1028-1033
    • Wang, Y.1    Li, Q.2    Fan, Z.3    Wang, Y.4    Qiu, Y.5    Jin, B.6    Chen, X.7    Yin, P.8
  • 161
    • 84870652779 scopus 로고    scopus 로고
    • Significance and effect of tanshinone IIA on the expression of surviving in human bile duct carcinoma cell line
    • Qi, W.; Huang, Q.; Wang, C.; Qiu, L.; Yu, J. Significance and effect of tanshinone IIA on the expression of surviving in human bile duct carcinoma cell line. Chin. J. Hepatobiliary Surg. 2008, 16, 452-454.
    • (2008) Chin. J. Hepatobiliary Surg , vol.16 , pp. 452-454
    • Qi, W.1    Huang, Q.2    Wang, C.3    Qiu, L.4    Yu, J.5
  • 162
    • 84863247218 scopus 로고    scopus 로고
    • Tanshinone IIA arrests cell cycle and induces apoptosis in 786-O human renal cell carcinoma cells
    • Wei, X.; Zhou, L.; Hu, L.; Huang, Y. Tanshinone IIA arrests cell cycle and induces apoptosis in 786-O human renal cell carcinoma cells. Oncol. Lett. 2012, 3, 1144-1148.
    • (2012) Oncol. Lett , vol.3 , pp. 1144-1148
    • Wei, X.1    Zhou, L.2    Hu, L.3    Huang, Y.4
  • 163
    • 79551595325 scopus 로고    scopus 로고
    • Tanshinone IIA acts via p38 MAPK to induce apoptosis and the down-regulation of ERCC1 and lung-resistance protein in cisplatin-resistant ovarian cancer cells
    • Jiao, J.W.; Wen, F. Tanshinone IIA acts via p38 MAPK to induce apoptosis and the down-regulation of ERCC1 and lung-resistance protein in cisplatin-resistant ovarian cancer cells. Oncol. Rep. 2011, 25, 781-788.
    • (2011) Oncol. Rep , vol.25 , pp. 781-788
    • Jiao, J.W.1    Wen, F.2
  • 164
    • 84870705877 scopus 로고    scopus 로고
    • The effects of inhibition and inducing apoptosis of Tanshinone II A on human ovarian cancer A2780 cell lines
    • Zhu, M.; Chen, P.; Chen, D.; Shi, X.; Kong, X.; Guo, L.; Zheng, F. The effects of inhibition and inducing apoptosis of Tanshinone II A on human ovarian cancer A2780 cell lines. J. Emerg. Tradit. Chin. Med. 2009, 18, 596-597.
    • (2009) J. Emerg. Tradit. Chin. Med , vol.18 , pp. 596-597
    • Zhu, M.1    Chen, P.2    Chen, D.3    Shi, X.4    Kong, X.5    Guo, L.6    Zheng, F.7
  • 165
    • 84870684772 scopus 로고    scopus 로고
    • The studies of apoptosis effect and its mechanisms of Tanshinone IIA on human ovarian cancer cell
    • Zhuang, Y.; Wang, H.; Du, R.; Zhang, C. The studies of apoptosis effect and its mechanisms of Tanshinone IIA on human ovarian cancer cell. J. Int. Obstet. Gynecol. 2011, 38, 328-331.
    • (2011) J. Int. Obstet. Gynecol , vol.38 , pp. 328-331
    • Zhuang, Y.1    Wang, H.2    Du, R.3    Zhang, C.4
  • 166
    • 84870679233 scopus 로고    scopus 로고
    • Induction of apoptosis by tanshinone IIA in HeLa cells
    • Meng, S.; Lu, X. Induction of apoptosis by tanshinone IIA in HeLa cells. J. Qiqihar Univ. Med. 2011, 32, 175-177.
    • (2011) J. Qiqihar Univ. Med , vol.32 , pp. 175-177
    • Meng, S.1    Lu, X.2
  • 167
    • 80052303169 scopus 로고    scopus 로고
    • Tanshinone IIA induces apoptosis in human nasopharyngeal carcinoma CNE1 cells
    • Zhao, J.; Xu, Q.; Sun, J.; Xu, X. Tanshinone IIA induces apoptosis in human nasopharyngeal carcinoma CNE1 cells. Acad. J. Second Mil. Med. Univ. 2011, 32, 879-883.
    • (2011) Acad. J. Second Mil. Med. Univ , vol.32 , pp. 879-883
    • Zhao, J.1    Xu, Q.2    Sun, J.3    Xu, X.4
  • 168
    • 80053940069 scopus 로고    scopus 로고
    • Apoptosis inducing effect of tanshinone II(A) on human nasopharyngeal carcinoma CNE cells
    • Dai, Z.; Huang, D.; Shi, J.; Yu, L.; Wu, Q.; Xu, Q. Apoptosis inducing effect of tanshinone II(A) on human nasopharyngeal carcinoma CNE cells. Zhongguo Zhongyao Zazhi 2011, 36, 2129-2133.
    • (2011) Zhongguo Zhongyao Zazhi , vol.36 , pp. 2129-2133
    • Dai, Z.1    Huang, D.2    Shi, J.3    Yu, L.4    Wu, Q.5    Xu, Q.6
  • 169
    • 33846965992 scopus 로고    scopus 로고
    • Growth inhibition and induction of apoptosis and differentiation of tanshinone IIA in human glioma cells
    • Wang, J.; Wang, X.; Jiang, S.; Yuan, S.; Lin, P.; Zhang, J.; Lu, Y.; Wang, Q.; Xiong, Z.; Wu, Y.; et al. Growth inhibition and induction of apoptosis and differentiation of tanshinone IIA in human glioma cells. J. Neurooncol. 2007, 82, 11-21.
    • (2007) J. Neurooncol , vol.82 , pp. 11-21
    • Wang, J.1    Wang, X.2    Jiang, S.3    Yuan, S.4    Lin, P.5    Zhang, J.6    Lu, Y.7    Wang, Q.8    Xiong, Z.9    Wu, Y.10
  • 170
    • 84855238447 scopus 로고    scopus 로고
    • Tanshinone IIA induces apoptosis and inhibits the proliferation, migration, and invasion of the osteosarcoma MG-63 cell line in vitro
    • Zhang, Y.; Wei, R.X.; Zhu, X.B.; Cai, L.; Jin, W.; Hu, H. Tanshinone IIA induces apoptosis and inhibits the proliferation, migration, and invasion of the osteosarcoma MG-63 cell line in vitro. Anticancer. Drugs 2012, 23, 212-219.
    • (2012) Anticancer. Drugs , vol.23 , pp. 212-219
    • Zhang, Y.1    Wei, R.X.2    Zhu, X.B.3    Cai, L.4    Jin, W.5    Hu, H.6
  • 171
    • 67449083388 scopus 로고    scopus 로고
    • Tanshinone IIA inhibits leukemia THP-1 cell growth by induction of apoptosis
    • Liu, J.J.; Zhang, Y.; Lin, D.J.; Xiao, R.Z. Tanshinone IIA inhibits leukemia THP-1 cell growth by induction of apoptosis. Oncol. Rep. 2009, 21, 1075-1081.
    • (2009) Oncol. Rep , vol.21 , pp. 1075-1081
    • Liu, J.J.1    Zhang, Y.2    Lin, D.J.3    Xiao, R.Z.4
  • 172
    • 0344197546 scopus 로고    scopus 로고
    • In vitro cytotoxicity of tanshinones isolated from Salvia miltiorrhiza Bunge against P388 lymphocytic leukemia cells
    • Mosaddik, M.A. In vitro cytotoxicity of tanshinones isolated from Salvia miltiorrhiza Bunge against P388 lymphocytic leukemia cells. Phytomedicine 2003, 10, 682-685.
    • (2003) Phytomedicine , vol.10 , pp. 682-685
    • Mosaddik, M.A.1
  • 173
    • 78549263680 scopus 로고    scopus 로고
    • C/EBPbeta and CHOP participate in tanshinone IIA-induced differentiation and apoptosis of acute promyelocytic leukemia cells in vitro
    • Zhang, K.; Li, J.; Meng, W.; Xing, H.; Yang, Y. C/EBPbeta and CHOP participate in tanshinone IIA-induced differentiation and apoptosis of acute promyelocytic leukemia cells in vitro. Int. J. Hematol. 2010, 92, 571-578.
    • (2010) Int. J. Hematol , vol.92 , pp. 571-578
    • Zhang, K.1    Li, J.2    Meng, W.3    Xing, H.4    Yang, Y.5
  • 174
    • 82755173238 scopus 로고    scopus 로고
    • Apoptosis of human leukemic HL-60 cells induced by Tanshinone IIA
    • Huang, R.; Yuan, S.; Song, Y.; Huang, G. Apoptosis of human leukemic HL-60 cells induced by Tanshinone IIA. J. Cancer 1998, 17, 164-166.
    • (1998) J. Cancer , vol.17 , pp. 164-166
    • Huang, R.1    Yuan, S.2    Song, Y.3    Huang, G.4
  • 175
    • 84861883201 scopus 로고    scopus 로고
    • Anti-tumor effect of tanshinone II, tetrandrine, honokiol, curcumin, oridonin and paeonol on leukemia cell lines
    • Shan, D.; Gong, Y.; Guo, Y.; Lin, J.; Zhou, R.; Yang, X. Anti-tumor effect of tanshinone II, tetrandrine, honokiol, curcumin, oridonin and paeonol on leukemia cell lines. Sichuan Daxue Xuebao Yixueban 2012, 43, 362-366.
    • (2012) Sichuan Daxue Xuebao Yixueban , vol.43 , pp. 362-366
    • Shan, D.1    Gong, Y.2    Guo, Y.3    Lin, J.4    Zhou, R.5    Yang, X.6
  • 176
    • 50849129920 scopus 로고    scopus 로고
    • Tanshinone IIA, an isolated compound from Salvia miltiorrhiza Bunge, induces apoptosis in HeLa cells through mitotic arrest
    • Zhou, L.; Chan, W.K.; Xu, N.; Xiao, K.; Luo, H.; Luo, K.Q.; Chang, D.C. Tanshinone IIA, an isolated compound from Salvia miltiorrhiza Bunge, induces apoptosis in HeLa cells through mitotic arrest. Life Sci. 2008, 83, 394-403.
    • (2008) Life Sci , vol.83 , pp. 394-403
    • Zhou, L.1    Chan, W.K.2    Xu, N.3    Xiao, K.4    Luo, H.5    Luo, K.Q.6    Chang, D.C.7
  • 177
    • 84863136847 scopus 로고    scopus 로고
    • Epidermal growth factor induces tumour marker AKR1B10 expression through activator protein-1 signalling in hepatocellular carcinoma cells
    • Liu, Z.; Yan, R.; Al-Salman, A.; Shen, Y.; Bu, Y.; Ma, J.; Luo, D.X.; Huang, C.; Jiang, Y.; Wilber, A.; et al. Epidermal growth factor induces tumour marker AKR1B10 expression through activator protein-1 signalling in hepatocellular carcinoma cells. Biochem. J. 2012, 442, 273-282.
    • (2012) Biochem. J , vol.442 , pp. 273-282
    • Liu, Z.1    Yan, R.2    Al-Salman, A.3    Shen, Y.4    Bu, Y.5    Ma, J.6    Luo, D.X.7    Huang, C.8    Jiang, Y.9    Wilber, A.10
  • 178
    • 77951210369 scopus 로고    scopus 로고
    • Effects of cryptotanshinone on proliferation and apoptosis of Hela cell line of cervical cancer
    • Ye, Y.; Xu, W.; Zhong, W. Effects of cryptotanshinone on proliferation and apoptosis of Hela cell line of cervical cancer. Zhongguo Zhongyao Zazhi 2010, 35, 118-121.
    • (2010) Zhongguo Zhongyao Zazhi , vol.35 , pp. 118-121
    • Ye, Y.1    Xu, W.2    Zhong, W.3
  • 179
    • 84870708400 scopus 로고    scopus 로고
    • The effects of cryptotanshinone on the expression of survivin in human cholangiocarcinoma cell of HCCC-9810
    • Chen, C.; Gong, J.; Miao, H.; Lin, H.; Lin, J. The effects of cryptotanshinone on the expression of survivin in human cholangiocarcinoma cell of HCCC-9810. Guangdong Med. J. 2001, 32, 3028-3031.
    • (2001) Guangdong Med. J. , vol.32 , pp. 3028-3031
    • Chen, C.1    Gong, J.2    Miao, H.3    Lin, H.4    Lin, J.5
  • 181
    • 77955452597 scopus 로고    scopus 로고
    • Cryptotanshinone inhibits cancer cell proliferation by suppressing Mammalian target of rapamycin-mediated cyclin D1 expression and Rb phosphorylation
    • Chen, W.; Luo, Y.; Liu, L.; Zhou, H.; Xu, B.; Han, X.; Shen, T.; Liu, Z.; Lu, Y.; Huang, S. Cryptotanshinone inhibits cancer cell proliferation by suppressing Mammalian target of rapamycin-mediated cyclin D1 expression and Rb phosphorylation. Cancer Prev. Res. 2010, 3, 1015-1025.
    • (2010) Cancer Prev. Res , vol.3 , pp. 1015-1025
    • Chen, W.1    Luo, Y.2    Liu, L.3    Zhou, H.4    Xu, B.5    Han, X.6    Shen, T.7    Liu, Z.8    Lu, Y.9    Huang, S.10
  • 182
    • 84864351010 scopus 로고    scopus 로고
    • Cryptotanshinone induces cell cycle arrest and apoptosis of multidrug resistant human chronic myeloid leukemia cells by inhibiting the activity of eukaryotic initiation factor 4E
    • Ge, Y.; Cheng, R.; Zhou, Y.; Shen, J.; Peng, L.; Xu, X.; Dai, Q.; Liu, P.; Wang, H.; Ma, X.; et al. Cryptotanshinone induces cell cycle arrest and apoptosis of multidrug resistant human chronic myeloid leukemia cells by inhibiting the activity of eukaryotic initiation factor 4E. Mol. Cell. Biochem. 2012, 368, 17-25.
    • (2012) Mol. Cell. Biochem , vol.368 , pp. 17-25
    • Ge, Y.1    Cheng, R.2    Zhou, Y.3    Shen, J.4    Peng, L.5    Xu, X.6    Dai, Q.7    Liu, P.8    Wang, H.9    Ma, X.10
  • 183
    • 58249119435 scopus 로고    scopus 로고
    • Cryptotanshinone inhibits constitutive signal transducer and activator of transcription 3 function through blocking the dimerization in DU145 prostate cancer cells
    • Shin, D.S.; Kim, H.N.; Shin, K.D.; Yoon, Y.J.; Kim, S.J.; Han, D.C.; Kwon, B.M. Cryptotanshinone inhibits constitutive signal transducer and activator of transcription 3 function through blocking the dimerization in DU145 prostate cancer cells. Cancer Res. 2009, 69, 193-202.
    • (2009) Cancer Res , vol.69 , pp. 193-202
    • Shin, D.S.1    Kim, H.N.2    Shin, K.D.3    Yoon, Y.J.4    Kim, S.J.5    Han, D.C.6    Kwon, B.M.7
  • 184
    • 33947574564 scopus 로고    scopus 로고
    • Targeting signal-transducer-and-activator-of-transcription-3 for prevention and therapy of cancer: Modern target but ancient solution
    • Aggarwal, B.B.; Sethi, G.; Ahn, K.S.; Sandur, S.K.; Pandey, M.K.; Kunnumakkara, A.B.; Sung, B.; Ichikawa, H. Targeting signal-transducer-and-activator-of-transcription-3 for prevention and therapy of cancer: modern target but ancient solution. Ann. NY Acad. Sci. 2006, 1091, 151-169.
    • (2006) Ann. NY Acad. Sci , vol.1091 , pp. 151-169
    • Aggarwal, B.B.1    Sethi, G.2    Ahn, K.S.3    Sandur, S.K.4    Pandey, M.K.5    Kunnumakkara, A.B.6    Sung, B.7    Ichikawa, H.8
  • 185
    • 0032726122 scopus 로고    scopus 로고
    • STAT proteins as novel targets for cancer therapy. Signal transducer an activator of transcription
    • Catlett-Falcone, R.; Dalton, W.S.; Jove, R. STAT proteins as novel targets for cancer therapy. Signal transducer an activator of transcription. Curr. Opin. Oncol. 1999, 11, 490-496.
    • (1999) Curr. Opin. Oncol , vol.11 , pp. 490-496
    • Catlett-Falcone, R.1    Dalton, W.S.2    Jove, R.3
  • 186
    • 0034676267 scopus 로고    scopus 로고
    • Induction of p21WAF1/CIP1 and cyclin D1 expression by the Src oncoprotein in mouse fibroblasts: Role of activated STAT3 signaling
    • Sinibaldi, D.; Wharton, W.; Turkson, J.; Bowman, T.; Pledger, W.J.; Jove, R. Induction of p21WAF1/CIP1 and cyclin D1 expression by the Src oncoprotein in mouse fibroblasts: Role of activated STAT3 signaling. Oncogene 2000, 19, 5419-5427.
    • (2000) Oncogene , vol.19 , pp. 5419-5427
    • Sinibaldi, D.1    Wharton, W.2    Turkson, J.3    Bowman, T.4    Pledger, W.J.5    Jove, R.6
  • 187
    • 0037441888 scopus 로고    scopus 로고
    • Inhibition of STAT3 signaling induces apoptosis and decreases survivin expression in primary effusion lymphoma
    • Aoki, Y.; Feldman, G.M.; Tosato, G. Inhibition of STAT3 signaling induces apoptosis and decreases survivin expression in primary effusion lymphoma. Blood 2003, 101, 1535-1542.
    • (2003) Blood , vol.101 , pp. 1535-1542
    • Aoki, Y.1    Feldman, G.M.2    Tosato, G.3
  • 189
    • 74449089539 scopus 로고    scopus 로고
    • Tanshinone IIA inhibits constitutive STAT3 activation, suppresses proliferation, and induces apoptosis in rat C6 glioma cells
    • Tang, C.; Xue, H.L.; Huang, H.B.; Wang, X.G. Tanshinone IIA inhibits constitutive STAT3 activation, suppresses proliferation, and induces apoptosis in rat C6 glioma cells. Neurosci. Lett. 2010, 470, 126-129.
    • (2010) Neurosci. Lett , vol.470 , pp. 126-129
    • Tang, C.1    Xue, H.L.2    Huang, H.B.3    Wang, X.G.4
  • 190
    • 77956945287 scopus 로고    scopus 로고
    • Cryptotanshinone sensitizes DU145 prostate cancer cells to Fas(APO1/CD95)-mediated apoptosis through Bcl-2 and MAPK regulation
    • Park, I.J.; Kim, M.J.; Park, O.J.; Park, M.G.; Choe, W.; Kang, I.; Kim, S.S.; Ha, J. Cryptotanshinone sensitizes DU145 prostate cancer cells to Fas(APO1/CD95)-mediated apoptosis through Bcl-2 and MAPK regulation. Cancer Lett. 2010, 298, 88-98.
    • (2010) Cancer Lett , vol.298 , pp. 88-98
    • Park, I.J.1    Kim, M.J.2    Park, O.J.3    Park, M.G.4    Choe, W.5    Kang, I.6    Kim, S.S.7    Ha, J.8
  • 191
    • 78751695438 scopus 로고    scopus 로고
    • Growth inhibition of tanshinones on SPC-A-1 cell line and their structure-activity relationship
    • Shi, H.; Zhang, Q.; Li, H.; Chu, T.; Jin, H.; Mao, S. Growth inhibition of tanshinones on SPC-A-1 cell line and their structure-activity relationship. Zhongguo Feiai Zazhi 2011, 14, 7-12.
    • (2011) Zhongguo Feiai Zazhi , vol.14 , pp. 7-12
    • Shi, H.1    Zhang, Q.2    Li, H.3    Chu, T.4    Jin, H.5    Mao, S.6
  • 192
    • 70349301394 scopus 로고    scopus 로고
    • Reactive oxygen species-mediated kinase activation by dihydrotanshinone in tanshinones-induced apoptosis in HepG2 cells
    • Lee, W.Y.; Liu, K.W.; Yeung, J.H. Reactive oxygen species-mediated kinase activation by dihydrotanshinone in tanshinones-induced apoptosis in HepG2 cells. Cancer Lett. 2009, 285, 46-57.
    • (2009) Cancer Lett , vol.285 , pp. 46-57
    • Lee, W.Y.1    Liu, K.W.2    Yeung, J.H.3
  • 193
    • 35349017930 scopus 로고    scopus 로고
    • Anti-tumor potential of 15,16-dihydrotanshinone I against breast adenocarcinoma through inducing G1 arrest and apoptosis
    • Tsai, S.L.; Suk, F.M.; Wang, C.I.; Liu, D.Z.; Hou, W.C.; Lin, P.J.; Hung, L.F.; Liang, Y.C. Anti-tumor potential of 15,16-dihydrotanshinone I against breast adenocarcinoma through inducing G1 arrest and apoptosis. Biochem. Pharmacol. 2007, 74, 1575-1586.
    • (2007) Biochem. Pharmacol , vol.74 , pp. 1575-1586
    • Tsai, S.L.1    Suk, F.M.2    Wang, C.I.3    Liu, D.Z.4    Hou, W.C.5    Lin, P.J.6    Hung, L.F.7    Liang, Y.C.8
  • 194
    • 79952171029 scopus 로고    scopus 로고
    • 15,16-Dihydrotanshinone I, a compound of Salvia miltiorrhiza Bunge, induces apoptosis through inducing endoplasmic reticular stress in human prostate carcinoma cells
    • 10.1155/2011/865435
    • Chuang, M.T.; Ho, F.M.; Wu, C.C.; Zhuang, S.Y.; Lin, S.Y.; Suk, F.M.; Liang, Y.C. 15,16-Dihydrotanshinone I, a compound of Salvia miltiorrhiza Bunge, induces apoptosis through inducing endoplasmic reticular stress in human prostate carcinoma cells. Evid. Based Complement. Alternat. Med. 2011, doi:10.1155/2011/865435.
    • (2011) Evid. Based Complement. Alternat. Med
    • Chuang, M.T.1    Ho, F.M.2    Wu, C.C.3    Zhuang, S.Y.4    Lin, S.Y.5    Suk, F.M.6    Liang, Y.C.7
  • 195
    • 84860111877 scopus 로고    scopus 로고
    • Arsenic trioxide for management of acute promyelocytic leukemia: Current evidence on its role in front-line therapy and recurrent disease
    • Breccia, M.; Lo-Coco, F. Arsenic trioxide for management of acute promyelocytic leukemia: Current evidence on its role in front-line therapy and recurrent disease. Expert Opin. Pharmacother. 2012, 13, 1031-1043.
    • (2012) Expert Opin. Pharmacother , vol.13 , pp. 1031-1043
    • Breccia, M.1    Lo-Coco, F.2
  • 196
    • 84255194993 scopus 로고    scopus 로고
    • Current treatment strategy of acute promyelocytic leukemia
    • Mi, J. Current treatment strategy of acute promyelocytic leukemia. Front. Med. 2011, 5, 341-347.
    • (2011) Front. Med , vol.5 , pp. 341-347
    • Mi, J.1
  • 197
    • 62249169964 scopus 로고    scopus 로고
    • Differentiation therapy of acute myeloid leukemia: Past, present and future
    • Petrie, K.; Zelent, A.; Waxman, S. Differentiation therapy of acute myeloid leukemia: Past, present and future. Curr. Opin. Hematol. 2009, 16, 84-91.
    • (2009) Curr. Opin. Hematol , vol.16 , pp. 84-91
    • Petrie, K.1    Zelent, A.2    Waxman, S.3
  • 198
    • 84870695355 scopus 로고    scopus 로고
    • Tanshinone II A induced differentiation of HL-60 cell line in vitro
    • Yuan, S.; Huang, R.; Song, Y.; Wang, X.; Huang, G.; Yang, Y. Tanshinone II A induced differentiation of HL-60 cell line in vitro. J. Pract. Oncol. 1997, 11, 253-256.
    • (1997) J. Pract. Oncol , vol.11 , pp. 253-256
    • Yuan, S.1    Huang, R.2    Song, Y.3    Wang, X.4    Huang, G.5    Yang, Y.6
  • 199
    • 1842869950 scopus 로고    scopus 로고
    • Acute promyelocytic leukemia cell differentiation induced by tanshinone II A and its molecular mechanism
    • Liang, Y.; Yang, Y.; Yuan, S.; Meng, W.; Liu, T.; Jia, Y. Acute promyelocytic leukemia cell differentiation induced by tanshinone II A and its molecular mechanism. Zhonghua Xueyexue Zazhi 2000, 21, 23-26.
    • (2000) Zhonghua Xueyexue Zazhi , vol.21 , pp. 23-26
    • Liang, Y.1    Yang, Y.2    Yuan, S.3    Meng, W.4    Liu, T.5    Jia, Y.6
  • 200
    • 62249160628 scopus 로고    scopus 로고
    • Study of molecular mechanism of tanshinone II A inducing differentiation in acute promyelocytic leukemia NB4 cells
    • Du, R.; Zheng, H.; Wang, Y.P.; Meng, W.T.; Qin, H.; Yuan, S.L. Study of molecular mechanism of tanshinone II A inducing differentiation in acute promyelocytic leukemia NB4 cells. Zhongguo Zhongyao Zazhi 2008, 33, 2954-2958.
    • (2008) Zhongguo Zhongyao Zazhi , vol.33 , pp. 2954-2958
    • Du, R.1    Zheng, H.2    Wang, Y.P.3    Meng, W.T.4    Qin, H.5    Yuan, S.L.6
  • 201
    • 1542463930 scopus 로고    scopus 로고
    • Study on the differentiation of K562 cell-line induced by Tanshinone II A
    • Wu, Y.; Yang, Y.; Meng, W.; Li, Y.; Jia, Y.; Liu, T. Study on the differentiation of K562 cell-line induced by Tanshinone II A. Huaxi Yike Daxue Xuebao 2002, 33, 80-83.
    • (2002) Huaxi Yike Daxue Xuebao , vol.33 , pp. 80-83
    • Wu, Y.1    Yang, Y.2    Meng, W.3    Li, Y.4    Jia, Y.5    Liu, T.6
  • 202
    • 33745545921 scopus 로고    scopus 로고
    • A study on the cell differentiation induced by tanshinone IIA and its molecular mechanism in retinoic acid: Resistant acute promyelocytic leukemia
    • Liang, Y.; Song, W.X.; Wang, J.; Jing, L.P.; Qu, W.; Fu, R.; Wu, X.Z. A study on the cell differentiation induced by tanshinone IIA and its molecular mechanism in retinoic acid: Resistant acute promyelocytic leukemia. Zhonghua Neike Zazhi 2005, 44, 366-369.
    • (2005) Zhonghua Neike Zazhi , vol.44 , pp. 366-369
    • Liang, Y.1    Song, W.X.2    Wang, J.3    Jing, L.P.4    Qu, W.5    Fu, R.6    Wu, X.Z.7
  • 203
    • 0346355634 scopus 로고    scopus 로고
    • Terminal differentiation of human acute promyelocytic leukemia (APL) cells induced by Tanshinone II A in primary culture
    • Liang, Y.; Yang, Y.; Yuan, S.; Liu, T.; Jia, Y.; Xu, C.; Niu, T.; Qin, H.; Qin, P. Terminal differentiation of human acute promyelocytic leukemia (APL) cells induced by Tanshinone II A in primary culture. Huaxi Yike Daxue Xuebao 2000, 31, 207-210.
    • (2000) Huaxi Yike Daxue Xuebao , vol.31 , pp. 207-210
    • Liang, Y.1    Yang, Y.2    Yuan, S.3    Liu, T.4    Jia, Y.5    Xu, C.6    Niu, T.7    Qin, H.8    Qin, P.9
  • 204
    • 9244220073 scopus 로고    scopus 로고
    • Differentiation and apoptosis of NB4 cells synergistically induced by Tanshinone II A and all-trans retinoic acid
    • Liu, Z.G.; Yang, Y.M.; Meng, W.T.; Huang, C.L. Differentiation and apoptosis of NB4 cells synergistically induced by Tanshinone II A and all-trans retinoic acid. Sichuan Daxue Xuebao Yi Xue Ban 2004, 35, 788-791.
    • (2004) Sichuan Daxue Xuebao Yi Xue Ban , vol.35 , pp. 788-791
    • Liu, Z.G.1    Yang, Y.M.2    Meng, W.T.3    Huang, C.L.4
  • 205
    • 0036683653 scopus 로고    scopus 로고
    • CCAAT/enhancer-binding proteins: Structure, function and regulation
    • Ramji, D.P.; Foka, P. CCAAT/enhancer-binding proteins: structure, function and regulation. Biochem. J. 2002, 365, 561-575.
    • (2002) Biochem. J , vol.365 , pp. 561-575
    • Ramji, D.P.1    Foka, P.2
  • 206
    • 0034774852 scopus 로고    scopus 로고
    • Ectopic expression of CCAAT/enhancer binding protein beta (C/EBPbeta) in long-term bone marrow cultures induces granulopoiesis and alters stromal cell function
    • Popernack, P.M.; Truong, L.T.; Kamphuis, M.; Henderson, A.J. Ectopic expression of CCAAT/enhancer binding protein beta (C/EBPbeta) in long-term bone marrow cultures induces granulopoiesis and alters stromal cell function. J. Hematother. Stem Cell Res. 2001, 10, 631-642.
    • (2001) J. Hematother. Stem Cell Res , vol.10 , pp. 631-642
    • Popernack, P.M.1    Truong, L.T.2    Kamphuis, M.3    Henderson, A.J.4
  • 207
    • 0026546365 scopus 로고
    • CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription
    • Ron, D.; Habener, J.F. CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription. Genes Dev. 1992, 6, 439-453.
    • (1992) Genes Dev , vol.6 , pp. 439-453
    • Ron, D.1    Habener, J.F.2
  • 208
    • 0034141568 scopus 로고    scopus 로고
    • TGF-alpha differentially regulates GFAP, vimentin, and nestin gene expression in U-373 MG glioblastoma cells: Correlation with cell shape and motility
    • Zhou, R.; Skalli, O. TGF-alpha differentially regulates GFAP, vimentin, and nestin gene expression in U-373 MG glioblastoma cells: Correlation with cell shape and motility. Exp. Cell Res. 2000, 254, 269-278.
    • (2000) Exp. Cell Res , vol.254 , pp. 269-278
    • Zhou, R.1    Skalli, O.2
  • 209
    • 2942614751 scopus 로고    scopus 로고
    • Differentiation-inducing activity of neomycin in cultured rat glioma cells
    • Cuevas, P.; Diaz-Gonzalez, D.; Dujovny, M. Differentiation-inducing activity of neomycin in cultured rat glioma cells. Neurochem. Res. 2004, 26, 401-403.
    • (2004) Neurochem. Res , vol.26 , pp. 401-403
    • Cuevas, P.1    Diaz-Gonzalez, D.2    Dujovny, M.3
  • 210
    • 0029840238 scopus 로고    scopus 로고
    • Tanshinone-induced differentiation in human cervical carcinoma cell line ME180
    • Huang, G.; Yuan, S.; Zhou, H.; Jiang, Y. Tanshinone-induced differentiation in human cervical carcinoma cell line ME180. Chin. J. Pharmacol. Toxicol. 1996, 10, 285-289.
    • (1996) Chin. J. Pharmacol. Toxicol , vol.10 , pp. 285-289
    • Huang, G.1    Yuan, S.2    Zhou, H.3    Jiang, Y.4
  • 211
    • 70350132289 scopus 로고    scopus 로고
    • The effect of TanshinoneIIA on the morphology and terminal differentiation of MG-63 cell
    • Shi, S.; Wang, G.; Ma, Z.; Shi, J.; Lin, C.; Li, Q. The effect of TanshinoneIIA on the morphology and terminal differentiation of MG-63 cell. Prog. Mod. Biomed. 2008, 8, 801-804.
    • (2008) Prog. Mod. Biomed , vol.8 , pp. 801-804
    • Shi, S.1    Wang, G.2    Ma, Z.3    Shi, J.4    Lin, C.5    Li, Q.6
  • 212
    • 77950931419 scopus 로고    scopus 로고
    • Matrix metalloproteinases: Regulators of the tumor microenvironment
    • Kessenbrock, K.; Plaks, V.; Werb, Z. Matrix metalloproteinases: Regulators of the tumor microenvironment. Cell 2010, 141, 52-67.
    • (2010) Cell , vol.141 , pp. 52-67
    • Kessenbrock, K.1    Plaks, V.2    Werb, Z.3
  • 213
    • 0036984640 scopus 로고    scopus 로고
    • Role of angiogenesis in tumor growth and metastasis
    • Folkman, J. Role of angiogenesis in tumor growth and metastasis. Semin. Oncol. 2002, 29, 15-18.
    • (2002) Semin. Oncol , vol.29 , pp. 15-18
    • Folkman, J.1
  • 214
    • 0034648765 scopus 로고    scopus 로고
    • Angiogenesis in cancer and other diseases
    • Carmeliet, P.; Jain, R.K. Angiogenesis in cancer and other diseases. Nature 2000, 407, 249-257.
    • (2000) Nature , vol.407 , pp. 249-257
    • Carmeliet, P.1    Jain, R.K.2
  • 215
    • 17644404758 scopus 로고    scopus 로고
    • Tanshinone: An inhibitor of proliferation of vascular smooth muscle cells
    • Wang, H.; Gao, X.; Zhang, B. Tanshinone: An inhibitor of proliferation of vascular smooth muscle cells. J. Ethnopharmacol. 2005, 99, 93-98.
    • (2005) J. Ethnopharmacol , vol.99 , pp. 93-98
    • Wang, H.1    Gao, X.2    Zhang, B.3
  • 216
    • 80051695345 scopus 로고    scopus 로고
    • Anti-angiogenic effect of Tanshinone IIA involves inhibition of matrix invasion and modification of MMP-2/TIMP-2 secretion in vascular endothelial cells
    • Tsai, M.Y.; Yang, R.C.; Wu, H.T.; Pang, J.H.; Huang, S.T. Anti-angiogenic effect of Tanshinone IIA involves inhibition of matrix invasion and modification of MMP-2/TIMP-2 secretion in vascular endothelial cells. Cancer Lett. 2011, 310, 198-206.
    • (2011) Cancer Lett , vol.310 , pp. 198-206
    • Tsai, M.Y.1    Yang, R.C.2    Wu, H.T.3    Pang, J.H.4    Huang, S.T.5
  • 217
    • 75649096054 scopus 로고    scopus 로고
    • Anti-migration and anti-angiogenic effects of tanshinone IIA on breast cancer cell MDA-MB-435
    • Xu, C.; Xi, T. Anti-migration and anti-angiogenic effects of tanshinone IIA on breast cancer cell MDA-MB-435. J. Chin. Pharm. Univ. 2009, 40, 565-570.
    • (2009) J. Chin. Pharm. Univ , vol.40 , pp. 565-570
    • Xu, C.1    Xi, T.2
  • 218
    • 84870714472 scopus 로고    scopus 로고
    • Inhibitary effect of Tanshinone IIA on vasculogenic mimicry in human breast cancer cell line MDA-MB-231 in vitro
    • Gao, L.; Xu, C.; He, Y.; Xi, T. Inhibitary effect of Tanshinone IIA on vasculogenic mimicry in human breast cancer cell line MDA-MB-231 in vitro. Pharm. Clin. Res. 2011, 19, 315-317.
    • (2011) Pharm. Clin. Res , vol.19 , pp. 315-317
    • Gao, L.1    Xu, C.2    He, Y.3    Xi, T.4
  • 219
    • 79952021639 scopus 로고    scopus 로고
    • Effect of Tanshinone IIA on vascular endothelial growth factor expression in hepatocellular carcinoma cell line SMMC-7721
    • Fu, H.; He, S.; Xu, J.; Zhao, G.; Wang, Y.; Ren, M. Effect of Tanshinone IIA on vascular endothelial growth factor expression in hepatocellular carcinoma cell line SMMC-7721. J. Xi'an Jiaotong Univ. (Med. Sci.) 2009, 30, 115-118.
    • (2009) J. Xi'an Jiaotong Univ. (Med. Sci.) , vol.30 , pp. 115-118
    • Fu, H.1    He, S.2    Xu, J.3    Zhao, G.4    Wang, Y.5    Ren, M.6
  • 220
    • 84870712061 scopus 로고    scopus 로고
    • Influence of Tanshinone IIA on cell proliferation and vascular endothelial growth factor expression in human bile duct carcinoma cell line HCCC-9810
    • Zhou, J.; Zheng, J.; Xiao, W.; Liu, Y. Influence of Tanshinone IIA on cell proliferation and vascular endothelial growth factor expression in human bile duct carcinoma cell line HCCC-9810. J. Chongqing Med. Univ. 2010, 35, 1798-1801.
    • (2010) J. Chongqing Med. Univ , vol.35 , pp. 1798-1801
    • Zhou, J.1    Zheng, J.2    Xiao, W.3    Liu, Y.4
  • 221
    • 68949149644 scopus 로고    scopus 로고
    • Effects of Tan II A on the proliferation, apoptosis and expression of HIF-1α of human gastric cancer cell line SGC7901 under hypoxia
    • Zong, X.; Feng, Y.; Wang, X.; Xing, G.; Wu, M.; Zhu, Y. Effects of Tan II A on the proliferation, apoptosis and expression of HIF-1α of human gastric cancer cell line SGC7901 under hypoxia. World Chin. J. Digestol. 2009, 17, 642-646.
    • (2009) World Chin. J. Digestol , vol.17 , pp. 642-646
    • Zong, X.1    Feng, Y.2    Wang, X.3    Xing, G.4    Wu, M.5    Zhu, Y.6
  • 222
    • 79952018753 scopus 로고    scopus 로고
    • Effects of Tan IIA on the expression of HIF-1α and c-Myc in gastric cancer SGC-7901 cell under hypoxia
    • Feng, Y.; Zong, X.; Xing, G.; Wu, M.; Zhu, Y. Effects of Tan IIA on the expression of HIF-1α and c-Myc in gastric cancer SGC-7901 cell under hypoxia. Shandong Med. J. 2010, 50, 7-8.
    • (2010) Shandong Med. J , vol.50 , pp. 7-8
    • Feng, Y.1    Zong, X.2    Xing, G.3    Wu, M.4    Zhu, Y.5
  • 223
    • 75349110250 scopus 로고    scopus 로고
    • Tanshinone IIA inhibits angiogenesis in subcutaneous colorectal cancer xenografts in mice
    • Zhou, L.; Liu, X.; Wang, Y.; Fan, Z.; Sun, Y.; Li, Q. Tanshinone IIA inhibits angiogenesis in subcutaneous colorectal cancer xenografts in mice. World Chin. J. Digestol. 2009, 17, 3203-3209.
    • (2009) World Chin. J. Digestol , vol.17 , pp. 3203-3209
    • Zhou, L.1    Liu, X.2    Wang, Y.3    Fan, Z.4    Sun, Y.5    Li, Q.6
  • 224
    • 18744369947 scopus 로고    scopus 로고
    • Cryptotanshinone but not tanshinone IIA inhibits angiogenesis in vitro
    • Hur, J.M.; Shim, J.S.; Jung, H.J.; Kwon, H.J. Cryptotanshinone but not tanshinone IIA inhibits angiogenesis in vitro. Exp. Mol. Med. 2005, 37, 133-137.
    • (2005) Exp. Mol. Med , vol.37 , pp. 133-137
    • Hur, J.M.1    Shim, J.S.2    Jung, H.J.3    Kwon, H.J.4
  • 226
    • 34548098412 scopus 로고    scopus 로고
    • Abietane diterpenes from Salvia miltiorrhiza inhibit the activation of hypoxia-inducible factor-1
    • Dat, N.T.; Jin, X.; Lee, J.H.; Lee, D.; Hong, Y.S.; Lee, K.; Kim, Y.H.; Lee, J.J. Abietane diterpenes from Salvia miltiorrhiza inhibit the activation of hypoxia-inducible factor-1. J. Nat. Prod. 2007, 70, 1093-1097.
    • (2007) J. Nat. Prod , vol.70 , pp. 1093-1097
    • Dat, N.T.1    Jin, X.2    Lee, J.H.3    Lee, D.4    Hong, Y.S.5    Lee, K.6    Kim, Y.H.7    Lee, J.J.8
  • 227
    • 38349057140 scopus 로고    scopus 로고
    • The antiangiogenesis effect of cryptotanshinone on chick embryo chorioallantoic membrane
    • Bian, W.; Xu, Y.; Wang, L.; Chen, F. The antiangiogenesis effect of cryptotanshinone on chick embryo chorioallantoic membrane. J. Chin. Microcirc. 2007, 12, 23-26.
    • (2007) J. Chin. Microcirc , vol.12 , pp. 23-26
    • Bian, W.1    Xu, Y.2    Wang, L.3    Chen, F.4
  • 228
    • 84870667794 scopus 로고    scopus 로고
    • Effects of certain drugs on the expression of antigens on human pulmonary giant cell carcinoma
    • Zhang, P.; Pei, Y.; Qi, X.; Pu, B. Effects of certain drugs on the expression of antigens on human pulmonary giant cell carcinoma. Chin. Tranit. Herbal Drugs 1999, 30, 352-355.
    • (1999) Chin. Tranit. Herbal Drugs , vol.30 , pp. 352-355
    • Zhang, P.1    Pei, Y.2    Qi, X.3    Pu, B.4
  • 229
    • 33845418736 scopus 로고    scopus 로고
    • Induction of apoptosis and inhibition of cell adhesive and invasive effects by tanshinone IIA in acute promyelocytic leukemia cells in vitro
    • Liu, J.J.; Lin, D.J.; Liu, P.Q.; Huang, M.; Li, X.D.; Huang, R.W. Induction of apoptosis and inhibition of cell adhesive and invasive effects by tanshinone IIA in acute promyelocytic leukemia cells in vitro. J. Biomed. Sci. 2006, 13, 813-823.
    • (2006) J. Biomed. Sci , vol.13 , pp. 813-823
    • Liu, J.J.1    Lin, D.J.2    Liu, P.Q.3    Huang, M.4    Li, X.D.5    Huang, R.W.6
  • 231
    • 76349098019 scopus 로고    scopus 로고
    • Tanshinone II-A inhibits invasion and metastasis of human hepatocellular carcinoma cells in vitro and in vivo
    • Xu, Y.; Tian, F.; Li, R.; Liu, Z. Tanshinone II-A inhibits invasion and metastasis of human hepatocellular carcinoma cells in vitro and in vivo. Tumori 2009, 95, 789-795.
    • (2009) Tumori , vol.95 , pp. 789-795
    • Xu, Y.1    Tian, F.2    Li, R.3    Liu, Z.4
  • 232
    • 79952028072 scopus 로고    scopus 로고
    • Inhibitory action of transhinone II A on human gastric cancer cell line MKN-45
    • Ye, Z.; Ye, P.; Yang, Q. Inhibitory action of transhinone II A on human gastric cancer cell line MKN-45. Chin. J. Surg. Integr. Tradit. West. Med. 2009, 15, 294-298.
    • (2009) Chin. J. Surg. Integr. Tradit. West. Med , vol.15 , pp. 294-298
    • Ye, Z.1    Ye, P.2    Yang, Q.3
  • 234
    • 77249083160 scopus 로고    scopus 로고
    • Tanshinone IIA protects against immune-mediated liver injury through activation of T-cell subsets and regulation of cytokines
    • Qin, X.Y.; Li, T.; Yan, L.; Liu, Q.S.; Tian, Y. Tanshinone IIA protects against immune-mediated liver injury through activation of T-cell subsets and regulation of cytokines. Immunopharmacol. Immunotoxicol. 2010, 32, 51-55.
    • (2010) Immunopharmacol. Immunotoxicol , vol.32 , pp. 51-55
    • Qin, X.Y.1    Li, T.2    Yan, L.3    Liu, Q.S.4    Tian, Y.5
  • 235
    • 0020816337 scopus 로고
    • Anti-inflammatory actions of tanshinone
    • Gao, Y.G. Anti-inflammatory actions of tanshinone. Zhong Xiyi Jiehe Zazhi 1983, 3, 300-301.
    • (1983) Zhong Xiyi Jiehe Zazhi , vol.3 , pp. 300-301
    • Gao, Y.G.1
  • 236
    • 0036846568 scopus 로고    scopus 로고
    • Effects of tanshinone I isolated from Salvia miltiorrhiza bunge on arachidonic acid metabolism and in vivo inflammatory responses
    • Kim, S.Y.; Moon, T.C.; Chang, H.W.; Son, K.H.; Kang, S.S.; Kim, H.P. Effects of tanshinone I isolated from Salvia miltiorrhiza bunge on arachidonic acid metabolism and in vivo inflammatory responses. Phytother. Res. 2002, 16, 616-620.
    • (2002) Phytother. Res , vol.16 , pp. 616-620
    • Kim, S.Y.1    Moon, T.C.2    Chang, H.W.3    Son, K.H.4    Kang, S.S.5    Kim, H.P.6
  • 237
    • 0346059348 scopus 로고    scopus 로고
    • Tanshinone IIA from Salvia miltiorrhiza inhibits inducible nitric oxide synthase expression and production of TNF-alpha, IL-1beta and IL-6 in activated RAW 264.7 cells
    • Jang, S.I.; Jeong, S.I.; Kim, K.J.; Kim, H.J.; Yu, H.H.; Park, R.; Kim, H.M.; You, Y.O. Tanshinone IIA from Salvia miltiorrhiza inhibits inducible nitric oxide synthase expression and production of TNF-alpha, IL-1beta and IL-6 in activated RAW 264.7 cells. Planta Med. 2003, 69, 1057-1059.
    • (2003) Planta Med , vol.69 , pp. 1057-1059
    • Jang, S.I.1    Jeong, S.I.2    Kim, K.J.3    Kim, H.J.4    Yu, H.H.5    Park, R.6    Kim, H.M.7    You, Y.O.8
  • 238
    • 33745849998 scopus 로고    scopus 로고
    • The structure and function of telomerase reverse transcriptase
    • Autexier, C.; Lue, N.F. The structure and function of telomerase reverse transcriptase. Annu. Rev. Biochem. 2006, 75, 493-517.
    • (2006) Annu. Rev. Biochem , vol.75 , pp. 493-517
    • Autexier, C.1    Lue, N.F.2
  • 239
    • 85047697807 scopus 로고    scopus 로고
    • TERT regulates cell survival independent of telomerase enzymatic activity
    • Cao, Y.; Li, H.; Deb, S.; Liu, J.P. TERT regulates cell survival independent of telomerase enzymatic activity. Oncogene 2002, 21, 3130-3138.
    • (2002) Oncogene , vol.21 , pp. 3130-3138
    • Cao, Y.1    Li, H.2    Deb, S.3    Liu, J.P.4
  • 240
    • 14844301658 scopus 로고    scopus 로고
    • HTERT antagonizes p53-induced apoptosis independently of telomerase activity
    • Rahman, R.; Latonen, L.; Wiman, K.G. hTERT antagonizes p53-induced apoptosis independently of telomerase activity. Oncogene 2005, 24, 1320-1327.
    • (2005) Oncogene , vol.24 , pp. 1320-1327
    • Rahman, R.1    Latonen, L.2    Wiman, K.G.3
  • 242
    • 2342535980 scopus 로고    scopus 로고
    • Change of telomerase activities before and after the leukemia cell differentiation induced by Tanshinone
    • Qin, P.; Yang, Y.; Qu, Y.; Yuan, S.; Meng, W.; Liang, Y.; Liu, T.; Jia, Y. Change of telomerase activities before and after the leukemia cell differentiation induced by Tanshinone. J. West China Univ. Med. Sci. 2002, 33, 397-400.
    • (2002) J. West China Univ. Med. Sci , vol.33 , pp. 397-400
    • Qin, P.1    Yang, Y.2    Qu, Y.3    Yuan, S.4    Meng, W.5    Liang, Y.6    Liu, T.7    Jia, Y.8
  • 243
    • 84870687693 scopus 로고    scopus 로고
    • Effect of Tanshinone IIA on expression of human telomerase reverse transcriptase in HL-60 cells
    • Li, H.; Liu, X.; Wang, H.; Wang, J.; Qu, Y.; Mu, D. Effect of Tanshinone IIA on expression of human telomerase reverse transcriptase in HL-60 cells. J. Appl. Clin. Pediatr. 2012, 27, 170-172.
    • (2012) J. Appl. Clin. Pediatr , vol.27 , pp. 170-172
    • Li, H.1    Liu, X.2    Wang, H.3    Wang, J.4    Qu, Y.5    Mu, D.6
  • 244
    • 21444433926 scopus 로고    scopus 로고
    • Alteration of activities of telomerase in tanshinone IIA inducing apoptosis of the leukemia cells
    • Song, Y.; Yuan, S.L.; Yang, Y.M.; Wang, X.J.; Huang, G.Q. Alteration of activities of telomerase in tanshinone IIA inducing apoptosis of the leukemia cells. Zhongguo Zhongyao Zazhi 2005, 30, 207-211.
    • (2005) Zhongguo Zhongyao Zazhi , vol.30 , pp. 207-211
    • Song, Y.1    Yuan, S.L.2    Yang, Y.M.3    Wang, X.J.4    Huang, G.Q.5
  • 245
    • 77954771133 scopus 로고    scopus 로고
    • Down-regulation of telomerase activity and activation of caspase-3 are responsible for tanshinone I-induced apoptosis in monocyte leukemia cells in vitro
    • Liu, X.D.; Fan, R.F.; Zhang, Y.; Yang, H.Z.; Fang, Z.G.; Guan, W.B.; Lin, D.J.; Xiao, R.Z.; Huang, R.W.; Huang, H.Q.; et al. Down-regulation of telomerase activity and activation of caspase-3 are responsible for tanshinone I-induced apoptosis in monocyte leukemia cells in vitro. Int. J. Mol. Sci. 2010, 11, 2267-2280.
    • (2010) Int. J. Mol. Sci , vol.11 , pp. 2267-2280
    • Liu, X.D.1    Fan, R.F.2    Zhang, Y.3    Yang, H.Z.4    Fang, Z.G.5    Guan, W.B.6    Lin, D.J.7    Xiao, R.Z.8    Huang, R.W.9    Huang, H.Q.10
  • 246
    • 81255208416 scopus 로고    scopus 로고
    • Ortho-Quinone tanshinones directly inhibit telomerase through an oxidative mechanism mediated by hydrogen peroxide
    • Soares, J.; Keppler, B.R.; Wang, X.; Lee, K.H.; Jarstfer, M.B. ortho-Quinone tanshinones directly inhibit telomerase through an oxidative mechanism mediated by hydrogen peroxide. Bioorg. Med. Chem. Lett. 2011, 21, 7474-7478.
    • (2011) Bioorg. Med. Chem. Lett , vol.21 , pp. 7474-7478
    • Soares, J.1    Keppler, B.R.2    Wang, X.3    Lee, K.H.4    Jarstfer, M.B.5
  • 247
    • 0347724051 scopus 로고    scopus 로고
    • Inhibition of telomerase activity by preventing proper assemblage
    • Keppler, B.R.; Jarstfer, M.B. Inhibition of telomerase activity by preventing proper assemblage. Biochemistry 2004, 43, 334-343.
    • (2004) Biochemistry , vol.43 , pp. 334-343
    • Keppler, B.R.1    Jarstfer, M.B.2
  • 249
    • 33746030307 scopus 로고    scopus 로고
    • The biochemical role of the heat shock protein 90 chaperone complex in establishing human telomerase activity
    • Keppler, B.R.; Grady, A.T.; Jarstfer, M.B. The biochemical role of the heat shock protein 90 chaperone complex in establishing human telomerase activity. J. Biol. Chem. 2006, 281, 19840-19848.
    • (2006) J. Biol. Chem , vol.281 , pp. 19840-19848
    • Keppler, B.R.1    Grady, A.T.2    Jarstfer, M.B.3
  • 250
    • 57349086300 scopus 로고    scopus 로고
    • Tanshinone IIA interacts with DNA by minor groove-binding
    • Zhang, Z.; Zhang, J.; Jin, L.; Song, T.; Wu, G.; Gao, J. Tanshinone IIA interacts with DNA by minor groove-binding. Biol. Pharm. Bull. 2008, 31, 2342-2345.
    • (2008) Biol. Pharm. Bull , vol.31 , pp. 2342-2345
    • Zhang, Z.1    Zhang, J.2    Jin, L.3    Song, T.4    Wu, G.5    Gao, J.6
  • 251
    • 70349567473 scopus 로고    scopus 로고
    • Tanshinone IIA triggers p53 responses and apoptosis by RNA polymerase II upon DNA minor groove binding
    • Zhang, Z.; Gao, J.; Wang, Y.; Song, T.; Zhang, J.; Wu, G.; Zhang, T.; Du, G. Tanshinone IIA triggers p53 responses and apoptosis by RNA polymerase II upon DNA minor groove binding. Biochem. Pharmacol. 2009, 78, 1316-1322.
    • (2009) Biochem. Pharmacol , vol.78 , pp. 1316-1322
    • Zhang, Z.1    Gao, J.2    Wang, Y.3    Song, T.4    Zhang, J.5    Wu, G.6    Zhang, T.7    Du, G.8
  • 252
    • 5044227858 scopus 로고    scopus 로고
    • Transcription and DNA adducts: What happens when the message gets cut off?
    • Scicchitano, D.A.; Olesnicky, E.C.; Dimitri, A. Transcription and DNA adducts: What happens when the message gets cut off? DNA repair (Amst) 2004, 3, 1537-1548.
    • (2004) DNA Repair (Amst) , vol.3 , pp. 1537-1548
    • Scicchitano, D.A.1    Olesnicky, E.C.2    Dimitri, A.3
  • 253
    • 0023263628 scopus 로고
    • Effect of drug-DNA interactions upon transcription initiation at the lac promoter
    • Straney, D.C.; Crothers, D.M. Effect of drug-DNA interactions upon transcription initiation at the lac promoter. Biochemistry 1987, 26, 1987-1995.
    • (1987) Biochemistry , vol.26 , pp. 1987-1995
    • Straney, D.C.1    Crothers, D.M.2
  • 254
    • 0028230037 scopus 로고
    • A DNA minor groove-binding ligand both potentiates and arrests transcription by RNA polymerase II. Elongation factor SII enables readthrough at arrest sites
    • Mote, J.; Ghanouni, P.; Reines, D. A DNA minor groove-binding ligand both potentiates and arrests transcription by RNA polymerase II. Elongation factor SII enables readthrough at arrest sites. J. Mol. Biol. 1994, 236, 725-737.
    • (1994) J. Mol. Biol , vol.236 , pp. 725-737
    • Mote, J.1    Ghanouni, P.2    Reines, D.3
  • 255
    • 65949097927 scopus 로고    scopus 로고
    • DNA double helix unwinding triggers transcription block-dependent apoptosis: A semiquantitative probe of the response of ATM, RNAPII, and p53 to two DNA intercalators
    • Zhang, Z.; Wang, Y.; Song, T.; Gao, J.; Wu, G.; Zhang, J.; Qian, X. DNA double helix unwinding triggers transcription block-dependent apoptosis: A semiquantitative probe of the response of ATM, RNAPII, and p53 to two DNA intercalators. Chem. Res. Toxicol. 2009, 22, 483-491.
    • (2009) Chem. Res. Toxicol , vol.22 , pp. 483-491
    • Zhang, Z.1    Wang, Y.2    Song, T.3    Gao, J.4    Wu, G.5    Zhang, J.6    Qian, X.7
  • 256
    • 0035807072 scopus 로고    scopus 로고
    • Ultraviolet radiation alters the phosphorylation of RNA polymerase II large subunit and accelerates its proteasome-dependent degradation
    • Luo, Z.; Zheng, J.; Lu, Y.; Bregman, D.B. Ultraviolet radiation alters the phosphorylation of RNA polymerase II large subunit and accelerates its proteasome-dependent degradation. Mutat. Res. 2001, 486, 259-274.
    • (2001) Mutat. Res , vol.486 , pp. 259-274
    • Luo, Z.1    Zheng, J.2    Lu, Y.3    Bregman, D.B.4
  • 257
    • 4544259868 scopus 로고    scopus 로고
    • Transcription-Guarding the genome by sensing DNA damage
    • Ljungman, M.; Lane, D.P. Transcription-Guarding the genome by sensing DNA damage. Nat. Rev. Cancer 2004, 4, 727-737.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 727-737
    • Ljungman, M.1    Lane, D.P.2
  • 258
    • 84862826362 scopus 로고    scopus 로고
    • Tanshinones from Chinese medicinal herb Danshen (Salvia miltiorrhiza Bunge) suppress prostate cancer growth and androgen receptor signaling
    • Zhang, Y.; Won, S.H.; Jiang, C.; Lee, H.J.; Jeong, S.J.; Lee, E.O.; Zhang, J.; Ye, M.; Kim, S.H.; Lu, J. Tanshinones from Chinese medicinal herb Danshen (Salvia miltiorrhiza Bunge) suppress prostate cancer growth and androgen receptor signaling. Pharm. Res. 2012, 29, 1595-1608.
    • (2012) Pharm. Res , vol.29 , pp. 1595-1608
    • Zhang, Y.1    Won, S.H.2    Jiang, C.3    Lee, H.J.4    Jeong, S.J.5    Lee, E.O.6    Zhang, J.7    Ye, M.8    Kim, S.H.9    Lu, J.10
  • 259
    • 0019062072 scopus 로고
    • Tanshinone in the treatment of acne (a primary report of 20 cases)
    • Wang, D.B.; Liu, A.S. Tanshinone in the treatment of acne (a primary report of 20 cases). Zhongguo Yixue Kexueyuan Xuebao 1980, 2, 187-188.
    • (1980) Zhongguo Yixue Kexueyuan Xuebao , vol.2 , pp. 187-188
    • Wang, D.B.1    Liu, A.S.2
  • 260
    • 79954525391 scopus 로고    scopus 로고
    • Effects of cryptotanshinone and tanshinone A on proliferation, lipid synthesis and expression of androgen receptor mRNA in human sebocytes in vitro
    • Ju, Q.; Yin, X.; Shi, J.; Xin, Y.; Kang, X.; Chen, Y.; Cui, P.; Cao, Y.; Xia, L. Effects of cryptotanshinone and tanshinone A on proliferation, lipid synthesis and expression of androgen receptor mRNA in human sebocytes in vitro. Chin. J. Dermatol. 2005, 38, 98-101.
    • (2005) Chin. J. Dermatol , vol.38 , pp. 98-101
    • Ju, Q.1    Yin, X.2    Shi, J.3    Xin, Y.4    Kang, X.5    Chen, Y.6    Cui, P.7    Cao, Y.8    Xia, L.9
  • 262
    • 84855350566 scopus 로고    scopus 로고
    • Cryptotanshinone suppresses androgen receptor-mediated growth in androgen dependent and castration resistant prostate cancer cells
    • Xu, D.; Lin, T.H.; Li, S.; Da, J.; Wen, X.Q.; Ding, J.; Chang, C.; Yeh, S. Cryptotanshinone suppresses androgen receptor-mediated growth in androgen dependent and castration resistant prostate cancer cells. Cancer Lett. 2012, 316, 11-22.
    • (2012) Cancer Lett , vol.316 , pp. 11-22
    • Xu, D.1    Lin, T.H.2    Li, S.3    Da, J.4    Wen, X.Q.5    Ding, J.6    Chang, C.7    Yeh, S.8
  • 263
    • 84860335030 scopus 로고    scopus 로고
    • The selective inhibitory effect of a synthetic tanshinone derivative on prostate cancer cells
    • Xu, D.; Lin, T.H.; Zhang, C.; Tsai, Y.C.; Li, S.; Zhang, J.; Yin, M.; Yeh, S.; Chang, C. The selective inhibitory effect of a synthetic tanshinone derivative on prostate cancer cells. Prostate 2012, 72, 803-816.
    • (2012) Prostate , vol.72 , pp. 803-816
    • Xu, D.1    Lin, T.H.2    Zhang, C.3    Tsai, Y.C.4    Li, S.5    Zhang, J.6    Yin, M.7    Yeh, S.8    Chang, C.9
  • 264
    • 84864125118 scopus 로고    scopus 로고
    • Cryptotanshinone down-regulates androgen receptor signaling by modulating lysine-specific demethylase 1 function
    • Wu, C.Y.; Hsieh, C.Y.; Huang, K.E.; Chang, C.; Kang, H.Y. Cryptotanshinone down-regulates androgen receptor signaling by modulating lysine-specific demethylase 1 function. Int. J. Cancer 2011, 131, 1423-1434.
    • (2011) Int. J. Cancer , vol.131 , pp. 1423-1434
    • Wu, C.Y.1    Hsieh, C.Y.2    Huang, K.E.3    Chang, C.4    Kang, H.Y.5
  • 265
    • 84863072889 scopus 로고    scopus 로고
    • Antiandrogenic, maspin induction, and antiprostate cancer activities of tanshinone IIA and its novel derivatives with modification in ring A
    • Liu, W.; Zhou, J.; Geng, G.; Shi, Q.; Sauriol, F.; Wu, J.H. Antiandrogenic, maspin induction, and antiprostate cancer activities of tanshinone IIA and its novel derivatives with modification in ring A. J. Med. Chem. 2012, 55, 971-975.
    • (2012) J. Med. Chem , vol.55 , pp. 971-975
    • Liu, W.1    Zhou, J.2    Geng, G.3    Shi, Q.4    Sauriol, F.5    Wu, J.H.6
  • 266
    • 77955499606 scopus 로고    scopus 로고
    • Effects of cryptotanshinone in lowering androgens synthesis for the prenatally androgenized male rats
    • Li, X.H.; Yang, X.M.; Wu, X.K. Effects of cryptotanshinone in lowering androgens synthesis for the prenatally androgenized male rats. Zhong Xiyi Jiehe Zazhi 2008, 28, 1001-1004.
    • (2008) Zhong Xiyi Jiehe Zazhi , vol.28 , pp. 1001-1004
    • Li, X.H.1    Yang, X.M.2    Wu, X.K.3
  • 267
    • 79954518825 scopus 로고    scopus 로고
    • Cryptotanshinone reverses reproductive and metabolic disturbances in prenatally androgenized rats via regulation of ovarian signaling mechanisms and androgen synthesis
    • Yang, X.; Zhang, Y.; Wu, X.; Bae, C.S.; Hou, L.; Kuang, H.; Wang, Y.; Stener-Victorin, E. Cryptotanshinone reverses reproductive and metabolic disturbances in prenatally androgenized rats via regulation of ovarian signaling mechanisms and androgen synthesis. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2011, 300, R869-R875.
    • (2011) Am. J. Physiol. Regul. Integr. Comp. Physiol , vol.300
    • Yang, X.1    Zhang, Y.2    Wu, X.3    Bae, C.S.4    Hou, L.5    Kuang, H.6    Wang, Y.7    Stener-Victorin, E.8
  • 268
    • 84870662423 scopus 로고    scopus 로고
    • Impact of cryptotanshinone on the reproductivity and metabolism of male mice with Akt2 deletion
    • Zhao, L.L.; Zhang, Y.H.; Wang, N.M.; Wu, X.K.; Hou, L.H. Impact of cryptotanshinone on the reproductivity and metabolism of male mice with Akt2 deletion. Zhonghua Nankexue 2011, 17, 662-668.
    • (2011) Zhonghua Nankexue , vol.17 , pp. 662-668
    • Zhao, L.L.1    Zhang, Y.H.2    Wang, N.M.3    Wu, X.K.4    Hou, L.H.5
  • 269
    • 78249254285 scopus 로고    scopus 로고
    • Activation of CYP3A-mediated testosterone 6beta-hydroxylation by tanshinone IIA and midazolam 1-hydroxylation by cryptotanshinone in human liver microsomes
    • Qiu, F.; Zhang, R.; Wang, G.; Gao, C.; Sun, J.; Jiang, J.; Ma, Y. Activation of CYP3A-mediated testosterone 6beta-hydroxylation by tanshinone IIA and midazolam 1-hydroxylation by cryptotanshinone in human liver microsomes. Xenobiotica 2010, 40, 800-806.
    • (2010) Xenobiotica , vol.40 , pp. 800-806
    • Qiu, F.1    Zhang, R.2    Wang, G.3    Gao, C.4    Sun, J.5    Jiang, J.6    Ma, Y.7
  • 270
    • 79955473621 scopus 로고    scopus 로고
    • Inhibitory effect of tanshinones on rat CYP3A2 and CYP2C11 activity and its structure-activity relationship
    • Wang, X.; Yeung, J.H. Inhibitory effect of tanshinones on rat CYP3A2 and CYP2C11 activity and its structure-activity relationship. Fitoterapia 2011, 82, 539-545.
    • (2011) Fitoterapia , vol.82 , pp. 539-545
    • Wang, X.1    Yeung, J.H.2
  • 271
    • 84870714051 scopus 로고    scopus 로고
    • Effect of Tanshinone II A combined with cisplatin on the growth and p53 protein expression of Hela cells
    • Zhou, A.; Hu, P.; Ren, Q.; Zhou, Y.; Huang, G.; Kong, X.; Guo, L.; Zheng, F. Effect of Tanshinone II A combined with cisplatin on the growth and p53 protein expression of Hela cells. J. Yunyang Med. Coll. 2007, 25, 339-341, 334.
    • J. Yunyang Med. Coll. 2007, 25 , vol.339-341 , pp. 334
    • Zhou, A.1    Hu, P.2    Ren, Q.3    Zhou, Y.4    Huang, G.5    Kong, X.6    Guo, L.7    Zheng, F.8
  • 273
    • 84870723040 scopus 로고    scopus 로고
    • Study on apoptosis and inhibited growth of human cervical carcinoma HeLa cell induced by Tanshinon II A and 5-FU
    • Wang, D.; Tian, Y.; Jiang, Y.; Ren, B.; Fang, Q.; Li, Y. Study on apoptosis and inhibited growth of human cervical carcinoma HeLa cell induced by Tanshinon II A and 5-FU. Chin J. Mod. Med. 2008, 18, 3237-3240.
    • (2008) Chin J. Mod. Med , vol.18 , pp. 3237-3240
    • Wang, D.1    Tian, Y.2    Jiang, Y.3    Ren, B.4    Fang, Q.5    Li, Y.6
  • 274
    • 34547169469 scopus 로고    scopus 로고
    • Effect of Tanshinone IIA combined with oxaliplatin on human hepatocellular carcinoma cell line SMMC-7721
    • Gao, J.; Zheng, S.; Liang, T.; Geng, L.; Wu, L. Effect of Tanshinone IIA combined with oxaliplatin on human hepatocellular carcinoma cell line SMMC-7721. Chin. Pharm. J. 2007, 42, 995-998.
    • (2007) Chin. Pharm. J , vol.42 , pp. 995-998
    • Gao, J.1    Zheng, S.2    Liang, T.3    Geng, L.4    Wu, L.5
  • 275
    • 84870720126 scopus 로고    scopus 로고
    • Effect of tanshinone II A on acquired multi-drug resistance of S180'S tumor and expression of P-gp, LRP and TOPO II in mice
    • He, X.; Zeng, B.; Liu, H. Effect of tanshinone II A on acquired multi-drug resistance of S180'S tumor and expression of P-gp, LRP and TOPO II in mice. J. Tradit. Chin. Med. Univ. Hunan 2010, 30, 16-18.
    • (2010) J. Tradit. Chin. Med. Univ. Hunan , vol.30 , pp. 16-18
    • He, X.1    Zeng, B.2    Liu, H.3
  • 277
    • 84862286997 scopus 로고    scopus 로고
    • Cryptotanshinone induces ER stress-mediated apoptosis in HepG2 and MCF7 cells
    • Park, I.J.; Kim, M.J.; Park, O.J.; Choe, W.; Kang, I.; Kim, S.S.; Ha, J. Cryptotanshinone induces ER stress-mediated apoptosis in HepG2 and MCF7 cells. Apoptosis 2012, 17, 248-257.
    • (2012) Apoptosis , vol.17 , pp. 248-257
    • Park, I.J.1    Kim, M.J.2    Park, O.J.3    Choe, W.4    Kang, I.5    Kim, S.S.6    Ha, J.7
  • 278
    • 84857909648 scopus 로고    scopus 로고
    • Combination treatment with dihydrotanshinone I and irradiation enhances apoptotic effects in human cervical cancer by HPV E6 down-regulation and caspases activation
    • Ye, Y.; Xu, W.; Zhong, W.; Li, Y.; Wang, C. Combination treatment with dihydrotanshinone I and irradiation enhances apoptotic effects in human cervical cancer by HPV E6 down-regulation and caspases activation. Mol. Cell. Biochem. 2012, 363, 191-202.
    • (2012) Mol. Cell. Biochem , vol.363 , pp. 191-202
    • Ye, Y.1    Xu, W.2    Zhong, W.3    Li, Y.4    Wang, C.5
  • 279
    • 33845235429 scopus 로고    scopus 로고
    • Complete remission of acute promyelocytic leukemia resisting all-trans retinoic acid of one case treated by tanshinone II A
    • Yang, Y.M.; Liu, T. Complete remission of acute promyelocytic leukemia resisting all-trans retinoic acid of one case treated by tanshinone II A. Sichuan Daxue Xuebao Yixueban 2006, 37, 965-967.
    • (2006) Sichuan Daxue Xuebao Yixueban , vol.37 , pp. 965-967
    • Yang, Y.M.1    Liu, T.2
  • 280
    • 78649819235 scopus 로고    scopus 로고
    • A successful case of tanshinone II A treatment for relapsed acute promyelocytic leukemia after maintainance therapy of all-trans retinoic acid and arsenic trioxide
    • Yang, L.; Gong, Y.P.; Yang, Y.M.; Luo, S. A successful case of tanshinone II A treatment for relapsed acute promyelocytic leukemia after maintainance therapy of all-trans retinoic acid and arsenic trioxide. Sichuan Daxue Xuebao Yixueban 2010, 41, 1065-1067.
    • (2010) Sichuan Daxue Xuebao Yixueban , vol.41 , pp. 1065-1067
    • Yang, L.1    Gong, Y.P.2    Yang, Y.M.3    Luo, S.4
  • 281
    • 84870689637 scopus 로고    scopus 로고
    • Study of composite Salviae miltiorrhizae injection on acute leukemia
    • Ji, B.; Wang, S.; Jing, B. Study of composite Salviae miltiorrhizae injection on acute leukemia. Mod. J. Integr. Tradit. Chin. West. Med. 2004, 28, 2958-2959.
    • (2004) Mod. J. Integr. Tradit. Chin. West. Med , vol.28 , pp. 2958-2959
    • Ji, B.1    Wang, S.2    Jing, B.3
  • 282
    • 84870724171 scopus 로고    scopus 로고
    • Clinical research on prevention of recurrence by trans-umbilical-portal vein perfusion of FufangDanshen in patients with hepatocellular carcinoma
    • Jiang, D.; Li, Q.; Ding, H.; Huang, J.; Wang, X.; Shi, L. Clinical research on prevention of recurrence by trans-umbilical-portal vein perfusion of FufangDanshen in patients with hepatocellular carcinoma. Pract. J. Cancer 2007, 22, 365-367.
    • (2007) Pract. J. Cancer , vol.22 , pp. 365-367
    • Jiang, D.1    Li, Q.2    Ding, H.3    Huang, J.4    Wang, X.5    Shi, L.6
  • 283
    • 84870714844 scopus 로고    scopus 로고
    • The efficiencies of hepatic artery infusion with the liquid compound of Radix Salvia miltiorrhizae and segmental hepatic artery chemoembolization in HCC
    • Li, Y.; Zhu, J.; Li, Y.; Wang, Y.; Zhang, W. The efficiencies of hepatic artery infusion with the liquid compound of Radix Salvia miltiorrhizae and segmental hepatic artery chemoembolization in HCC. Chin. Imaging J. Integr. Tradit. West. Med. 2006, 4, 352-355.
    • (2006) Chin. Imaging J. Integr. Tradit. West. Med , vol.4 , pp. 352-355
    • Li, Y.1    Zhu, J.2    Li, Y.3    Wang, Y.4    Zhang, W.5
  • 284
    • 84943234751 scopus 로고    scopus 로고
    • Effect of composite Salviae dropping pill combined with chemotherapy in 41 cases with pancreatic carcinoma
    • Chen, X.; Liang, Q.; Li, X.; Zhang, Y.; Li, J.; Liang, Z.; Zhang, Y. Effect of composite Salviae dropping pill combined with chemotherapy in 41 cases with pancreatic carcinoma. J. Oncol. 2005, 13, 49-51.
    • (2005) J. Oncol , vol.13 , pp. 49-51
    • Chen, X.1    Liang, Q.2    Li, X.3    Zhang, Y.4    Li, J.5    Liang, Z.6    Zhang, Y.7
  • 285
    • 36448980441 scopus 로고    scopus 로고
    • The cooperation group of phase II clinical trial of compound huangdai tablet: Phase II clinical trial of compound Huangdai tablet in newly diagnosed acute promyelocytic leukemia
    • Qian, L.; Zhao, Y. The cooperation group of phase II clinical trial of compound huangdai tablet: Phase II clinical trial of compound Huangdai tablet in newly diagnosed acute promyelocytic leukemia. Chin. J. Hematol. 2006, 27, 801-804.
    • (2006) Chin. J. Hematol , vol.27 , pp. 801-804
    • Qian, L.1    Zhao, Y.2
  • 286
    • 44449164173 scopus 로고    scopus 로고
    • The influence on long-term survey of the patients with acute promyelocytic leukemia treated alternatively with compound huangdai tablets and chemotherapy
    • Xiang, Y.; Huang, S.; Guo, A.; Wei, A.; Zhang, L.; Sun, S.; Chen, N.; Cheng, Y.; Wang, D. The influence on long-term survey of the patients with acute promyelocytic leukemia treated alternatively with compound huangdai tablets and chemotherapy. J. Clin. Hematol. 2003, 16, 204-206.
    • (2003) J. Clin. Hematol , vol.16 , pp. 204-206
    • Xiang, Y.1    Huang, S.2    Guo, A.3    Wei, A.4    Zhang, L.5    Sun, S.6    Chen, N.7    Cheng, Y.8    Wang, D.9
  • 287
    • 0001968572 scopus 로고
    • Clincal study on the treatment of acute promyelocytic leukemia mainly with composite indigo naturalis tablets
    • Huang, S.; Guo, A.; Xiang, Y.; Wang, X.; Lin, H.; Fu, L. Clincal study on the treatment of acute promyelocytic leukemia mainly with composite indigo naturalis tablets. Chin. J. Hematol. 1995, 16, 26-28.
    • (1995) Chin. J. Hematol , vol.16 , pp. 26-28
    • Huang, S.1    Guo, A.2    Xiang, Y.3    Wang, X.4    Lin, H.5    Fu, L.6
  • 288
    • 77955040667 scopus 로고
    • The clinical Sstudy of relapsed acute promyelocytic leukemia treated with compound Huangdai tablets
    • Cheng, Y.; Huang, S.; Xing, Y.; Chen, N.; Sun, F.; Guo, A.; Wei, A.; Zhang, L. The clinical Sstudy of relapsed acute promyelocytic leukemia treated with compound Huangdai tablets. J. Emerg. Tradit. Chin. Med. 2007, 16, 1066-1067, 1071.
    • (1071) J. Emerg. Tradit. Chin. Med , vol.2007 , Issue.16 , pp. 1066-1067
    • Cheng, Y.1    Huang, S.2    Xing, Y.3    Chen, N.4    Sun, F.5    Guo, A.6    Wei, A.7    Zhang, L.8
  • 289
    • 46049089210 scopus 로고    scopus 로고
    • Compound realgar and natural indigo tablets in treatment of acute promyelocytic leukemia: A summary of experience in 204 cases
    • Sun, F.; Chen, N.; Cheng, Y. Compound realgar and natural indigo tablets in treatment of acute promyelocytic leukemia: A summary of experience in 204 cases. Zhongxiyi Jiehe Xue Bao 2008, 6, 639-642.
    • (2008) Zhongxiyi Jiehe Xue Bao , vol.6 , pp. 639-642
    • Sun, F.1    Chen, N.2    Cheng, Y.3
  • 290
    • 46049118347 scopus 로고    scopus 로고
    • The analysis of therapeutic efficiency on treating acute promyelocytic leukemia (APL) with compound Huangdai tablets
    • Xiang, Y.; Huang, S.; Guo, A.; Wang, Q.; Zhang, C.; Yan, J.; Chen, A. The analysis of therapeutic efficiency on treating acute promyelocytic leukemia (APL) with compound Huangdai tablets. J. Clin. Hematol. 2000, 13, 11-12.
    • (2000) J. Clin. Hematol , vol.13 , pp. 11-12
    • Xiang, Y.1    Huang, S.2    Guo, A.3    Wang, Q.4    Zhang, C.5    Yan, J.6    Chen, A.7
  • 291
    • 79952563315 scopus 로고    scopus 로고
    • Induction of apoptosis by compound "Huang Dai" tablet In acute promyelocytic leukemia
    • Zhang, C.; Huang, S.; Xiang, Y.; Guo, A. Induction of apoptosis by compound "Huang Dai" tablet In acute promyelocytic leukemia. Med. J. Chin. People's Liberation Army 2003, 28, 556-557.
    • (2003) Med. J. Chin. People's Liberation Army , vol.28 , pp. 556-557
    • Zhang, C.1    Huang, S.2    Xiang, Y.3    Guo, A.4
  • 292
    • 42449161986 scopus 로고    scopus 로고
    • Dissection of mechanisms of Chinese medicinal formula Realgar-Indigo naturalis as an effective treatment for promyelocytic leukemia
    • Wang, L.; Zhou, G.B.; Liu, P.; Song, J.H.; Liang, Y.; Yan, X.J.; Xu, F.; Wang, B.S.; Mao, J.H.; Shen, Z.X.; et al. Dissection of mechanisms of Chinese medicinal formula Realgar-Indigo naturalis as an effective treatment for promyelocytic leukemia. Proc. Natl. Acad. Sci. USA 2008, 105, 4826-4831.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 4826-4831
    • Wang, L.1    Zhou, G.B.2    Liu, P.3    Song, J.H.4    Liang, Y.5    Yan, X.J.6    Xu, F.7    Wang, B.S.8    Mao, J.H.9    Shen, Z.X.10
  • 293
    • 33748524861 scopus 로고    scopus 로고
    • Antitumor agents. 254. Synthesis and biological evaluation of novel neo-tanshinlactone analogues as potent anti-breast cancer agents
    • Wang, X.; Nakagawa-Goto, K.; Bastow, K.F.; Don, M.J.; Lin, Y.L.; Wu, T.S.; Lee, K.H. Antitumor agents. 254. Synthesis and biological evaluation of novel neo-tanshinlactone analogues as potent anti-breast cancer agents. J. Med. Chem. 2006, 49, 5631-5634.
    • (2006) J. Med. Chem , vol.49 , pp. 5631-5634
    • Wang, X.1    Nakagawa-Goto, K.2    Bastow, K.F.3    Don, M.J.4    Lin, Y.L.5    Wu, T.S.6    Lee, K.H.7
  • 294
    • 78149281220 scopus 로고    scopus 로고
    • Neo-tanshinlactone inspired synthesis, in vitro evaluation of novel substituted benzocoumarin derivatives as potent anti-breast cancer agents
    • Sashidhara, K.V.; Rosaiah, J.N.; Kumar, M.; Gara, R.K.; Nayak, L.V.; Srivastava, K.; Bid, H.K.; Konwar, R. Neo-tanshinlactone inspired synthesis, in vitro evaluation of novel substituted benzocoumarin derivatives as potent anti-breast cancer agents. Bioorg. Med. Chem. Lett. 2010, 20, 7127-7131.
    • (2010) Bioorg. Med. Chem. Lett , vol.20 , pp. 7127-7131
    • Sashidhara, K.V.1    Rosaiah, J.N.2    Kumar, M.3    Gara, R.K.4    Nayak, L.V.5    Srivastava, K.6    Bid, H.K.7    Konwar, R.8
  • 295
    • 77949360201 scopus 로고    scopus 로고
    • Antitumor agents. 272. Structure-Activity relationships and in vivo selective anti-breast cancer activity of novel neo-tanshinlactone analogues
    • Dong, Y.; Shi, Q.; Pai, H.C.; Peng, C.Y.; Pan, S.L.; Teng, C.M.; Nakagawa-Goto, K.; Yu, D.; Liu, Y.N.; Wu, P.C.; et al. Antitumor agents. 272. Structure-Activity relationships and in vivo selective anti-breast cancer activity of novel neo-tanshinlactone analogues. J. Med. Chem. 2010, 53, 2299-2308.
    • (2010) J. Med. Chem , vol.53 , pp. 2299-2308
    • Dong, Y.1    Shi, Q.2    Pai, H.C.3    Peng, C.Y.4    Pan, S.L.5    Teng, C.M.6    Nakagawa-Goto, K.7    Yu, D.8    Liu, Y.N.9    Wu, P.C.10
  • 296
    • 79953324693 scopus 로고    scopus 로고
    • Antitumor agents 287. Substituted 4-amino-2H-pyran-2-one (APO) analogs reveal a new scaffold from neo-tanshinlactone with in vitro anticancer activity
    • Dong, Y.; Nakagawa-Goto, K.; Lai, C.Y.; Morris-Natschke, S.L.; Bastow, K.F.; Lee, K.H. Antitumor agents 287. Substituted 4-amino-2H-pyran-2-one (APO) analogs reveal a new scaffold from neo-tanshinlactone with in vitro anticancer activity. Bioorg. Med. Chem. Lett. 2011, 21, 2341-2344.
    • (2011) Bioorg. Med. Chem. Lett , vol.21 , pp. 2341-2344
    • Dong, Y.1    Nakagawa-Goto, K.2    Lai, C.Y.3    Morris-Natschke, S.L.4    Bastow, K.F.5    Lee, K.H.6
  • 297
    • 7444239691 scopus 로고    scopus 로고
    • Antitumor agents. 239. Isolation, structure elucidation, total synthesis, and anti-breast cancer activity of neo-tanshinlactone from Salvia miltiorrhiza
    • Wang, X.; Bastow, K.F.; Sun, C.M.; Lin, Y.L.; Yu, H.J.; Don, M.J.; Wu, T.S.; Nakamura, S.; Lee, K.H. Antitumor agents. 239. Isolation, structure elucidation, total synthesis, and anti-breast cancer activity of neo-tanshinlactone from Salvia miltiorrhiza. J. Med. Chem. 2004, 47, 5816-5819.
    • (2004) J. Med. Chem , vol.47 , pp. 5816-5819
    • Wang, X.1    Bastow, K.F.2    Sun, C.M.3    Lin, Y.L.4    Yu, H.J.5    Don, M.J.6    Wu, T.S.7    Nakamura, S.8    Lee, K.H.9
  • 298
    • 0021391219 scopus 로고
    • Therapeutic effect of sodium tanshinone IIA sulfonate in patients with coronary heart disease
    • Annoymous, A double blind study. Shanghai Cooperative Group for the Study of Tanshinone IIA
    • Annoymous. Therapeutic effect of sodium tanshinone IIA sulfonate in patients with coronary heart disease. A double blind study. Shanghai Cooperative Group for the Study of Tanshinone IIA. J. Tradit. Chin. Med. 1984, 4, 20-24.
    • (1984) J. Tradit. Chin. Med , vol.4 , pp. 20-24
  • 299
    • 0020381779 scopus 로고
    • The therapeutic effect of purified coronary heart II tablets on 112 cases of angina pectoris by double blind method
    • Chen, K. The therapeutic effect of purified coronary heart II tablets on 112 cases of angina pectoris by double blind method. Zhonghua Xinxueguanbing Zazhi 1982, 10, 85-89.
    • (1982) Zhonghua Xinxueguanbing Zazhi , vol.10 , pp. 85-89
    • Chen, K.1
  • 300
    • 0030621735 scopus 로고    scopus 로고
    • Comparative Study of composite Danshen droplet pills and sordi in treatment of patients with chronic stable angina
    • Shi, Y. Comparative Study of composite Danshen droplet pills and sordi in treatment of patients with chronic stable angina. Zhongguo Zhongxiyi Jiehe Zazhi 1997, 17, 23-25.
    • (1997) Zhongguo Zhongxiyi Jiehe Zazhi , vol.17 , pp. 23-25
    • Shi, Y.1
  • 301
    • 80052706331 scopus 로고    scopus 로고
    • Effect of supplementation of Tanshinone IIA and sodium Tanshinone IIA sulfonate on the anticancer effect of epirubicin: An in vitro study
    • 10.1155/2011/841564
    • Chan, S.E.; Lai, H.W.; Su, C.C.; Kuo, S.J.; Chien, S.Y.; Lin, H.Y.; Chen, D.R. Effect of supplementation of Tanshinone IIA and sodium Tanshinone IIA sulfonate on the anticancer effect of epirubicin: An in vitro study. Evid. Based Complement. Alternat. Med. 2011, doi:10.1155/2011/841564.
    • (2011) Evid. Based Complement. Alternat. Med
    • Chan, S.E.1    Lai, H.W.2    Su, C.C.3    Kuo, S.J.4    Chien, S.Y.5    Lin, H.Y.6    Chen, D.R.7
  • 302
    • 33846860595 scopus 로고    scopus 로고
    • A high throughput drug screen based on fluorescence resonance energy transfer (FRET) for anticancer activity of compounds from herbal medicine
    • Tian, H.; Ip, L.; Luo, H.; Chang, D.C.; Luo, K.Q. A high throughput drug screen based on fluorescence resonance energy transfer (FRET) for anticancer activity of compounds from herbal medicine. Br. J. Pharmacol. 2007, 150, 321-334.
    • (2007) Br. J. Pharmacol , vol.150 , pp. 321-334
    • Tian, H.1    Ip, L.2    Luo, H.3    Chang, D.C.4    Luo, K.Q.5


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